Theodor Förster's name is forever linked to FRET (Förster resonance energy transfer) and while his development of FRET theory is well known and recognized, only few is documented about his scientific career and life from 1933 to 1951. By reviewing documents from different archives, this Viewpoint Article discusses Förster's life and career before, during, and after National Socialism in Germany.

Over the past decade, red-emissive organic molecular crystals have advanced through molecular design (donor-acceptor structures, π-conjugation) and crystal engineering to overcome aggregation-caused quenching and energy gap limitations. Featuring high quantum yields, tunable deep-red/NIR emission, and flexibility, they enable applications in flexible waveguides, lasers, and bio-integrated optoelectronics.

From binary to higher-order organic cocrystals: strategic design principles, precision synthesis, and multifunctional applications. The emergence of ternary and higher-order cocrystalline systems, comprising three or more components, has revolutionized the paradigm of material design by significantly expanding both structural diversity and functional potential. These advanced architectures not only exhibit enhanced design versatility through synergistic molecular engineering but also enable unprecedented modulation of physicochemical properties, thereby introducing novel optoelectronic, mechanical, and stimuli-responsive functionalities.

A review goes to data-driven. An exhaustive literature survey provides an overview of research status on aerogels, a category of highly porous solids with unique physicochemical properties. Statistical/data-driven analysis tells us positive/negative aspects; aerogels have a promising potential to contribute to emerging energy/environmental issues, while they are causing an academic fever with irresponsible exaggerations and a flood of unreliable data.

Cations play a pivotal role in controlling electrocatalytic reaction pathways, selectivity, and kinetics. A deeper mechanistic understanding of cation effects offers opportunities to overcome the activity–selectivity trade-off in electrocatalytic reactions, enabling the rational design of more efficient electrolyte systems.

Design of effective bidirectional electrocatalyst focused on electronic interactions in lithium–sulfur batteries. Development of effective bidirectional catalyst is essential for high-energy density and long-life lithium–sulfur batteries. The catalytic activity of catalyst is directly related to the degree of the interaction between the catalysts and adsorbates. In the review, we introduce the design strategy for catalysts with high catalytic activity focused on the electronic structure and properties of catalysts and reactants.

Targeted protein degradation (TPD) has emerged as a powerful therapeutic approach, with numerous candidates molecules now advancing into clinical development. Recent innovations have incorporated nanoparticles to facilitate and enhance these degradation processes, yielding synergistic effects. This work provides a comprehensive overview of the current landscape of nanoparticle-mediated targeted degradation, outlining recent advances, key challenges, and future opportunities to guide progress in this rapidly evolving field.

An NIR spontaneously blinking fluorophore, Aze-HMSiR, optimized for long-term SMLM imaging of lysosomes is developed. It exhibits superior photostability, pH responsiveness, and minimal phototoxicity. Aze-HMSiR can reveal key lysosomal characteristics, including distribution, size, and lumen pH, in response to various anticancer agents. Such whole-cell lysosome SMLM imaging serves as a valuable indicator for lysosomal functional diagnostics.

Organoautocatalyzed transamination metathesis of cyclic tertiary amines is disclosed as a high-yielding, scalable reaction that proceeds under mild, catalyst-free conditions. It operates via a multi-step domino reaction mechanism, where an in situ-formed pyrrolidinium salt functions as a HBD organoautocatalyst. The reaction opens the door for the efficient synthesis of novel N-substituted DNDHPs of interest in both life and materials sciences.

A simple quinoid building block TTD, featuring small steric hindrance and high electron deficiency, was obtained via a one-step synthesis. Unexpectedly, the TTD-based polymers showed tunable charge carrier polarity from p-type to ambipolar and ultimately to n-type upon thermal annealing, and the n-doped polymers attained remarkable thermoelectric performance with a power factor of 36.7 µW m⁻¹ K⁻².

Self-assembly reactions of [Cp^RFe(η⁵-P₅)] (Cp^R = C₅(CH₃)₅ and C₅(4-EtC₆H₄)₅) with coinage metal salts and white phosphorus afforded an unprecedented novel class of mixed polyphosphorus ligand complexes in which metal ions multiply coordinate intact P₄ tetrahedra. The bulkiness of the used Cp^R ligand and the right choice of the solvent tune the structure and the content of P₄ in the coordination products that can release P₄ upon decomplexation.

We developed a molecular tethering agent, TTe-TTe, that binds to the octapeptide repeat region of glycosylated PrP^C. TTe-TTe suppresses malignant melanoma proliferation by triggering PrP^C to aggregate on the cell membrane surface, followed by its degradation. This versatile platform technology opens up new avenues for targeted protein degradation in a wide range of therapeutic applications, potentially advancing the field of drug discovery.

Two donor-acceptor 3D COFs synthesized via Schiff base reactions were integrated into perovskite solar cells’ SAMs. Their architecture enabled efficient charge separation, stable interfacial anchoring, and optimized energy alignment, enhancing hole transport and perovskite quality and reduced defect density. This achieving PCEs up to 25.20%, demonstrating COFs' potential in advancing PSC efficiency.

The advantages of peroxide redox chemistry are explored for green hydrogen production. Peroxide redox electrocatalysts enable efficient and selective peroxide production and oxidation, facilitating on-site hydrogen generation while achieving a nearly 50% reduction in applied potential compared to conventional water-splitting methods. An integrated bipolar-ion gradient system further reduces energy requirements to nearly one-third of traditional electrolysis.

We describe a modular and efficient nickel-catalyzed Markovnikov-selective hydroarylation of readily available allylic amines, affording various valuable arylethylamines with exclusive regiocontrol. The use of NHC─Ni catalyst was crucial to achieve high efficiency and selectivity. In particular, with bulky chiral NHC ligands, enantioenriched arylethylamines were prepared in high efficiency with excellent regio- and enantioselectivities.

Traditional charge-carrier-based photocatalysis can be switched to a novel energy transfer route for efficient and selective ¹O₂ generation through amide functionalization to modulate the electronic structure of the photocatalyst, thus providing a promising approach for simultaneous synthesis of H₂O₂ and conversion of a biomass derivative.

Ionic liquids have been proposed as alternatives to molecular solvents. Here, spin probes and spin-labelled ILs are studied by pulse electron paramagnetic resonance, paramagnetic relaxation enhancement NMR, molecular dynamics, and density functional theory, revealing the IL interaction sphere. The results challenge previous interpretations of nitroxide-solvent nanostructuring in ILs.

We report for the first time that the bromide ion, acting as a non-N-ligand in iron complexes with the tridentate N-ligand bis(2-pyridylmethyl)amine (BMPA), which is traditionally used in Fenton chemistry to degrade organic compounds, tames Fenton chemistry and enables chemo-selective, nondegrading oxidation reactions. This discovery of the bromide effect bridges the gap between Fenton chemistry and haloperoxidase-catalyzed halogenation, potentially inspiring further investigation into the “innocent” ligands of iron complexes for new reactivity and applications. The overlooked inorganic anion may be exploited in other catalytic systems.

The co-electrolysis of CO₂ and NO₃⁻ presents a promising route for sustainable urea production. Here, we show that in situ generated CO₂ bubbles within a bi(carbonate) reduction zero-gap electrolyzer can boost urea selectivity by engendering a high density of triple-phase boundaries.

We reported the discovery of confining carbon dots (CDs) into boric acid matrix realizing the precise regulation of color from red to white with delay time increase under white light (WL) excitation. And composites can emit persistent afterglow at high temperatures up to 393 K under WL excitation. Its time-dependent phosphorescence color (TDPC) and high stability lay a solid foundation for higher-order cryptographic and anticounterfeiting.

We show how photo switchable styryl cyanines undergo an extremely efficient photochemical ring-closing reaction upon irradiation. Furthermore, substituents on the ring and the nature of their surroundings can be used to tune their chemistry, kinetics, and photochemical properties. Finally, we demonstrate how these molecules can be used as smart dopants to control proton transport using light in a polymeric matrix.

Single-atom catalysts (SACs) depend on hierarchical coordination environments, yet higher-order shells (>2nd) critically influence electronic structures via long-range charge delocalization. This study pioneers long-range interaction engineering in single-atom catalysts (SACs) for CO₂ electroreduction. By tailoring pyrolysis of NiTPP to preserve Ni-N₄ coordination shell (first and second) while eliminating peripheral π-delocalization, the catalyst achieves a 29-fold CO efficiency boost (85.9% at −1.4 V) and 98.3% selectivity at 500 mA cm⁻².

A hydrogen-bonded organic framework with lithiophilic sites and hydrogen bond interaction with lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) can accelerate the desolvation process of lithium ion and guide the rapid and uniform deposition of Li⁺.

A molecular communication system has been developed to monitor Zn²⁺ ion transport-mediated chemical-to-optical signal amplification process.

An NMR-based study, combined with computational, calorimetric and in-cell FRET methods, sheds light on the complex recognition mechanism between the intrinsically disordered protein Tau and the SH3 domain of Fyn kinase, highlighting how the multiple binding sites present in Tau make the protein an adaptable recognition surface that can function even when single consensus motifs are eliminated.

We report a cobalt-catalyzed enantioselective double [2 + 2 + 2] cycloaddition between bisalkynyl malononitriles and terminal alkynes. Chiral spirobipyridines bearing ortho- and meta-substituents can be synthesized with the help of chiral bisoxazolinephosphine ligands.

We present a layer-by-layer assembly method to trap enzymes between covalent organic framework (COF) nanosheets instead for the construction of membrane bioreactors. This design boosts mass transfer, shields enzymes from harmful by-products, and enables rapid substrate conversion (complete in 7.95 s)—achieving 1018× higher activity than free enzymes. The reactor maintains stability under continuous use and works with diverse enzymes/COFs, offering a versatile platform for high-performance biocatalysts.

Mechanosensitive conjugated oligoelectrolytes (COEs) with integrated twistable bonds enable real-time imaging of membrane tension in lipid bilayers. Using fluorescence lifetime analysis, COE-BY probes reveal vesicle rigidity changes during endocytosis, providing insights into membrane mechanics at the subcellular level.

The synergistic strategies of the double asymmetric core and symmetric/asymmetric terminal engineering are applied to develop multiple-asymmetric acceptors. By delicately tuning the number and position of peripheral F and Cl atoms, the regioregular triple-asymmetric TASe-2F2Cl-based binary OSCs yield the first-class efficiency of 19.32% and ultralow nonradiative recombination energy loss (ΔE₃) among selenium-substituted acceptors.

Lipid nanoparticles (LNPs) containing an ionizable lipid with a thioamide adjacent to the tertiary amine have a lower pK_a than those containing an analogous lipid with a conventional amide, and exhibit significantly improved mRNA transfection efficiency both in vitro and in vivo.

Although computationally predicted, N₂ activation with an in situ generated low-valent β-diketiminate (BDI) Sr^I precursor did not result in a stable complex. First dinitrogen fixation with Sr was achieved using a heterobimetallic approach. This highly reducing product vigorously reacts with Teflon.

A new strategy accelerates rotary speed in overcrowded alkene-based molecular motors by tuning cycloparaphenylene loop size, preserving core structures. Strain energy variations drive hierarchical acceleration up to 389-fold. This study systematically reveals motor behavior under strain, offering new avenues for engineering light-driven nanomachines.

An innovative group transfer radical cyclopolymerization (GTRCP) method has been developed for the precise synthesis of functionalized cyclic olefin polymers (COPs) using non-conjugated diene monomers. Through rational monomer design, various polar groups are incorporated into the COP backbones. The resulting polymers exhibit high molecular weights, low dispersities, controllable chain sequences, and high structural diversity. The polymer can function as a robust interphase layer, enhancing the reversibility of lithium plating/stripping in anode-free lithium metal batteries.

Polyether monomers coordinate with aluminum ethoxide nanowires via in situ ultraviolet curing, stabilizing the lone pair electrons of ethereal oxygen atoms and suppressing oxidative degradation. This coordination also forms abundant and tight interfaces as the predominant lithium-ion conduction pathways, contributing to ordered lithium-ion fluxes. The composite gel polymer electrolyte facilitates high-performance Li||LiNi_0.6Co_0.2Mn_0.2O₂ cell.

We successfully developed the first BD1-targted covalent inhibitor (TCI), BDS4, by utilizing 2-ethynylbenzaldehyde (EBA). Importantly, BDS4 retained robust activity against fibrosis in cells and animals when compared to the marginal effects of BD2 inhibitor RVX-208. Our developed tool showed clear advantages of long-lasting domain-selective TCI in delineating the district function of BD1 and BD2.

AZD0156, an ATM kinase inhibitor in clinical development, shows promising multistage antiplasmodial activity by targeting Plasmodium falciparum phosphatidylinositol 4-kinase (PfPI4Kβ). With an improved specificity profile relative to other PfPI4Kβ inhibitors and moderate efficacy in a P. berghei disease model, AZD0156 is an attractive candidate for medicinal chemistry optimization against malaria.

A site-selective electrostatic co-assembly (SSECA) strategy was developed to fabricate a variety of topological heterostructures (THSs) with unprecedented architectures from two-component systems of organometallic complexes and block copolymers. The THSs are composed of rigid parts of closely stacked organometallic complexes and flexible segments formed from electrostatic co-assembly of BCPs and the complexes originally in the SPs.

A double-lock protected Pt^II nanomedicine has been developed, which performs cascade unlocking of cisplatin (cDDP) via catalytic-redox reactions, thus achieving tumor-specific “on-site” activation of cDDP in the nucleus accompanied with substantial induction of ferroptosis for highly efficient chemo-immunotherapy.

The non-covalent supramolecular and intermolecular charge-transfer (CT) strategy, employing bis-chromophoric pyromellitic diimides (PmDIs) and judicious choice of donors, enabled tunable circularly polarized delayed luminescence in the red region with a high quantum yield of ∼46% and a significant |g_lum| value of up to ∼3.6 × 10⁻².

This work reveals how entropy regulates sulfur utilization and cycling stability in aqueous Zn–S batteries. High-entropy (HES) catalysts enable optimized Zn–S redox pathways and structural integrity, achieving high sulfur utilization and stable cycling. In contrast, low- (LES) and medium-entropy (MES) catalysts show inefficient reactions with by-product formation and Mn/Co leaching, degrading performance. Practical validation demonstrates HES-based pouch cells maintain exceptional stability over 400 cycles at 4 C with merely 0.06% capacity decay per cycle, establishing entropy engineering as a practical design strategy.

The one-step acid-catalyzed condensation of phenacetin and its analogues with paraformaldehyde provides a facile route to hourglass-shaped phenacetin[3]arenes with distinct functionalized rims in good yields. These novel macrocyclic arene show excellent binding properties and offer the potential for chirality sensing.

Photoelectrocatalytic activation of C(sp³)─H bonds in hydrocarbon molecules to produce valuable oxygenates still suffers from the limited generation of reactive species and the weak adsorption of reactants. This study achieved the selective oxidation of toluene using a TiO₂ supported subnanometric PtO_x cluster (PtO_x/TiO₂) photoanode via an electrophilic OH*-mediated pathway. The modification of PtO_x cluster can facilitate toluene adsorption and OH* generation, leading to the high efficiency of toluene oxidation.

Phase transition from melt to most complex liquid crystal (LC) phases is weak 1st order but is preceded by a large heat capacity maximum. In addition, a chiral liquid forms through another transition before that to the LC, despite the compounds being achiral. We investigate these poorly understood phenomena experimentally and develop a statistical theory that fits the experiments remarkably well, giving new insights into the mechanism of self-assembly and pre-assembly.

The spatially controlled occlusion of polymeric nanoparticles into cuprous oxide (Cu₂O) systematically alters lattice distortion, oxygen vacancy content, and catalytic efficiency in the resulting composite crystals, offering a robust framework for the development of advanced functional composite materials.

The material descriptors are first proposed to guide the design and screening of high-energy density p-type organic cathode materials. Triphenylamine and synthesized p-PZA POP proved the rationality of these descriptors. Na||p-PZA POP batteries exhibit a surprisingly high energy density of 524.6 Wh kg⁻¹ at 1 A g⁻¹ and excellent wide-temperature electrochemical performance.

A synthetic protocol was developed to scale up ultramicroporous Zr-MOFs with simple formate, enabling one-step direct separation of C₂H₄ from the binary C₂H₂/C₂H₄ or ternary C₂H₂/CO₂/C₂H₄ gas mixtures with high separation efficiency and cost-saving preparation.

We design a series of halogenated COF nanoemitters via a covalent halogenation predesign strategy. The introduction of halogen atoms facilitates p–π conjugation within COF skeleton, leading to a 49-fold ECL enhancement compared to nonhalogenated COF. Furthermore, the performance of four partially brominated COFs establishes a positive correlation between the degree of Br doping and ECL intensity.

A new strategy to achieve solar-blind UV mechanoluminescent (ML) materials through strategically breaking the molecular conjugation and adjusting the packing mode. DPO3C and DPO4C exhibited solar-blind UV emission with the maxima at ca. 293 nm, with wide-range color-tunable ML emissions from 293 to 741 nm via host–guest doping. This study also paves the way for advancements in bright-field stress visualization.

A boron-modified Zn₃In₂S₆ photocatalyst is engineered, featuring In-B dual-active sites that establish dual-channel carrier transfer pathways and substantially prolong photogenerated carrier lifetimes five-fold. These synergistic effects enable direct one-step 2e⁻ ORR for efficient H₂O₂ production from O₂ in pure water, achieving a record apparent quantum yield of 49.8% at 365 nm among inorganic semiconductor photocatalysts.

Herein, we develop a novel SAM molecular design strategy by introducing fused-ring intramolecular donor–acceptor (D–A) interactions. The designed molecule, JJ32, features a benzo[5,6][1,4]thiazino[2,3-b]quinoxaline skeleton, where strong D–A interactions enhance charge delocalization and downshift the LUMO energy level. This leads to enhanced photostability, redox stability, and intermolecular interactions. Moreover, the improved redox stability benefits the promising polyoxometalate/SAM composite HSL, allowing the JJ32/HPWO-based OSC to reach 19.85% efficiency with improved stability.

Atomically dispersed low-coordination Mo on ultrathin ZnIn₂S₄ nanosheets has been successfully developed for acceptorless dehydrogenation of alcohols. The isolated Mo sites optimize the driving force of photogenerated holes, which greatly accelerates the electron transfer rate of the alkoxy C─H bonds, resulting in the formation of high-concentration alkyl radicals.

A simple and effective composite binder strategy is proposed to establish multiple and highly efficient Li⁺ transport channels within the LiFePO₄ cathode, which significantly improves the Li⁺ transport efficiency and achieves high-performance all-solid-state lithium batteries at high cathode active loading.

Based on the highly efficient Qx series of small molecules, we have synthesized T-Qxs, which are shamrock-shaped giant molecules with high glass transition temperature. The miscibility with the polymer donor PM6 was fine-tuned by modulation of the central and terminal atoms, thereby altering the molecular distortion angle. Organic solar cells (OSCs) based on the fully chlorine-substituted T-Qx-15Cl achieve both high power conversion efficiency (PCE) and high thermal stability.

A novel class of luminescent nematic liquid crystals (N-LCs) exhibiting full-color emission was developed. Through coassembly with chiral dopants, these N-LCs enabled the fabrication of high-brightness full-color and white circularly polarized luminescent (CPL) films with simultaneously enhanced g_lum (up to 0.75) and photoluminescence quantum yield (up to 71%), representing the best performance to date among all intrinsically luminescent CPL materials.

The photocatalytic conversion of CO₂ into higher carbon products demands precise catalyst engineering. In this study, we implemented a dual doping strategy in AgBiP₂S₆ to optimize charge density and enhance active sites for C─C coupling. This approach successfully enabled the synthesis of ethylene through the photoreduction of CO₂, showcasing the effectiveness of the modified catalyst design.

We report an iron-catalyzed radical allylic substitution method that directly functionalizes unprotected allylic alcohols, eliminating the need for prefunctionalization and toxic reagents. Utilizing iron's unique redox and oxophilic properties, this approach offers a step-economic and sustainable pathway to allylic functionalization. This method expands the synthetic toolbox and demonstrates the versatility of outer-sphere mechanisms in radical-based reactions, facilitating the efficient synthesis of diverse molecular architectures.

In this study, we investigated the potential of Li-rich manganese-based oxides as promising cathode materials for next-generation lithium-ion batteries, highlighting the critical challenges posed by low initial coulombic efficiency and irreversible oxygen release. We introduce a novel treatment method using Glyoxal, which facilitates the integration of transition metal 3d and oxygen 2p orbital hybridization, aimed at optimizing the electrochemical performance of LRMO. Our results demonstrate a significant improvement in ICE, increasing from 85.3% to 102.5%. Additionally, the treated LRMO achieves a high specific capacity of 291.2 mAh g⁻¹ at 0.1 C, surpassing untreated samples, and exhibits excellent cycling stability with retention rates of 90.1% after 150 cycles and 76.5% after 250 cycles at 0.5 C.

In this study, we synthesized a dihydrophenazine-based Pd₆L₁₂ coordination cage (Cage 1) with excellent redox activity. It can reversibly transform into its radical cation form (1^12•+) via electrochemical or chemical oxidation/reduction. Both forms' structures were determined by X-ray diffraction. In situ spectroelectrochemical techniques verified their redox reversibility and electrochromic behavior. Cage 1 was also used as a lithium battery cathode, with its redox behavior studied by in situ 2D EPR.

We report an all-in-one electrochemical energy system by coupling the rational conversions from nitrogen-oxysalts and biomass-derived-aldehydes (industrial/agricultural wastes). The poor reaction kinetics are efficaciously optimized by RhCu alloy electrocatalyst with dual-directional H*-modulation properties. So, nitrate and furfural can be simultaneously converted into multiple non-mixed valuable products (NH₃, H₂, etc.) with electricity output.

This work highlights a strategy that leverages site-specific spin state modulation in spinel oxides, which optimizes site-specific functionalities and enhances the overall nonradical oxidation reaction kinetics by 22-fold. XAS, magnetism characterization combined with theoretical calculation unveil the establishment of a QSEI that facilitates spin channel for charge transfer and the RDS desorption with a lower-ICOHP in fine-tuned spin states.

By tuning the rigidity and length of DNA bonds on M-DNAs, we demonstrate a universal strategy for designing 1D porous crystals with tailored geometries and topologies, enabling advanced catalytic applications.

A defect-engineered heteronuclear FeMn dual-atom catalyst on a porous N-doped carbon matrix is synthesized via a customized trinuclear-defect trapping strategy. The defect-mediated coordination strengthens Fe 3d_z² with O 2p orbital hybridization, optimizing adsorption energy toward Sabatier optimality. The catalyst delivers a 0.921 V half-wave potential for alkaline oxygen reduction and excellent Zn-air battery performance.

A dual-locked Pt(IV) prodrug combines a TLR7/8 agonist (IMDQ) with a GGT-responsive moiety. Reduction to Pt(II) triggers GGT-mediated cleavage of axial ligands, releasing IMDQ to activate immunity. TLR7/8 signaling boosts T-cell infiltration into tumors and stimulates tumor-associated macrophages (TAMs) and dendritic cells (DCs). Synergy between platinum chemotherapy and immune activation achieves potent antitumor efficacy.

A Mo/Ce co-doped Ni oxyhydroxide was prepared for the electrochemical oxidation of furfural coupled with hydrogen evolution. Mo promotes the adsorption of furfural while Ce promotes the formation of OOH, and the synergistic effect of Ce and Mo leads to an industrial current density of 1000 mA cm⁻² at only 1.46 V versus RHE.

A woven two-dimensional (2D) covalent organic polymer network (CityU-46) was designed, fabricated, and structurally resolved through single-crystal X-ray diffraction analysis, which revealed a unique, well-defined two-over, two-under interweaving pattern at the molecular level. CityU-46, serving as an artificial organic solid-electrolyte interphase layer on the surface of Li metal anodes, demonstrated excellent electrochemical performance in practical lithium metal cells.

A thermodynamically controlled nucleophilic germylation of stable π bonds was achieved by germyl anion generated in situ via heterolytic cleavage of the Ge─Ge bond in the presence of KO^tBu. This methodology enables unprecedented multiple germylation of alkynes and internally selective germylation of alkenes, affording 1-alkyl-1-germylalkanes, 1,1-digermylalkanes, and 1,1,1-trigermylalkanes.

A photoredox/nickel dual-catalyzed enantioselective decarboxylative acylation of α-hydroxy acid derivatives with carboxylic acids has been developed, enabling efficient access to enantioenriched α-oxygenated ketones. This method exhibits a broad substrate scope, good functional group tolerance, high chemoselectivity, and excellent enantioselectivity.

This investigation demonstrates an efficient synthetic methodology for the fabrication of atomically dispersed cobalt species anchored on carbon nitride substrate, featuring distinctive asymmetric Co─C₂N₃ coordination environments and hierarchical active sites. The unique electronic structure of this single-atom catalyst exhibits strengthened driving force and boosted charge carrier transport properties, manifesting in two-stage reaction kinetics during the photocatalytic degradation of bisphenol A contaminants in wastewater.

We prepared two imine macrocycles, SPAZ and STAZ, as analogues of 1,4-pyrazine and 1,3,5-triazine, respectively. SPAZ and STAZ exhibit Brønsted basicity with pK_a values of 0.97 and 3.27, respectively. Notably, we elucidate their unprecedented valence tautomerism between “super-Kekulé” benzenoid/quinoidal structures and a “super-sextet” transient structure, facilitated by aza[30]annulene pathways.

The confined BO_x@SiO₂ with highly dispersed BO_x species was synthesized by the in situ transformation of BN@SiO₂, which showed a remarkable activity of a unique C₃H₈ conversion uprush increasing from 5.3% at 410 °C to 28.4% at 424.6 °C for oxidative dehydrogenation of propane. The key for the efficient C₃H₈ activation was the increased amount of tri-coordinated B─OH derived from the dispersion of molten BO_x species within spatially confined SiO₂.

The controlled synthesis of noble metal-free CuNi alloy nanostructures with unconventional hcp/fcc heterophase has been successfully achieved. Notably, hcp/fcc CuNi nanoalloys demonstrate much superior catalytic performance toward ammonia electrosynthesis from nitrate than the common fcc CuNi counterparts. Mechanism studies reveal that the hcp/fcc CuNi alloys facilitate the formation of K⁺–H₂O, enhance the interfacial water dissociation, and create high *H coverage, thereby boosting the ammonia synthesis.

The Zn-doped Fe₂O₃ catalysts with Zn–O_V–Fe sites can promote the conversion of CO₂-to-*CO and the coupling of *NO + *CO and thus improve the urea electrosynthesis. It exhibits an outstanding urea faradaic efficiency of 62.4% with a production rate of 7.48 mg h⁻¹ mg_cat⁻¹.

The Cu₆Sn₅ alloy was developed as a high-performance, noble-metal-free electrocatalyst for the anodic formaldehyde oxidative dehydrogenation (FOD) reaction. When paired with the cathodic hydrogen evolution reaction (HER), it enables a formaldehyde-assisted water electrolyzer, facilitating energy-efficient bipolar hydrogen production and the generation of value-added formate.

We develop a unique strategy of information encryption/decryption based on stimuli-responsive luminescence of 2D hybrid organic–inorganic perovskites via delicate organic-cation engineering. The facile triple-key implementation working in multiple switching modes (featuring high contrast and quick response) allows us to achieve high security and readout efficiency, opening a new door to information security based on optical encryption.

FrazP2, a cytochrome P450, catalyzes cyclohexane ring formation in forazoline A, a marine-derived antifungal from Actinomadura sp. WMMB-499. Structural and mechanistic studies have uncovered a radical-mediated cyclization, unlocking opportunities to engineer P450s for the generation of novel antifungal forazoline analogues.

Second-sphere coordination regulation strategy is employed by atomically tailoring the metal–metal coordination of the secondary building unit (SBU), with efforts to trigger more orbital interactions with guest molecules. Amorphous metal-organic framework (a-MOF) is chosen to transform rigid trinuclear nodes into flexible dinuclear motifs. Such architecture with clear and unique second-sphere interaction can open spatial proximity to access the guest molecule and optimize s–π^* overlap by enabling orbital reorientation.

A metal-free and Markovnikov-type process for divergent hydroboration/multiboration of terminal alkynes has been achieved, enabling the transformation of diverse aryl and alkyl alkynes into valuable but previously inaccessible α-alkenylboronate, 2,2-diborylalkane, 1,2,2-triborylalkane, and 1,2-diborylalkane with excellent regio- and chemoselectivities by simply modulating the proton additive and solvent.

Atomically dispersed Cu–Ag sites on the catalyst surface promote the *OH cleavage of *COCOH toward *COO, thereby enhancing the selectivity of C₂₊ oxygenates from CO electroreduction. CO electrolysis over the optimized CuAg catalyst achieves a Faradaic efficiency of 71.4% for C₂₊ oxygenates at a current density of 2.5 A cm⁻² in alkaline membrane electrode assembly electrolyzer.

Dual emissions containing equalized thermally activated delayed fluorescence and phosphorescence are achieved by a copper iodide complex QtBCzTTPPCuI, which exhibits ∼100% photoluminescence quantum efficiencies and record-high twofold increased external quantum efficiencies of ∼30% among pure-yellow spin-coated organic light-emitting diodes, owing to the contributions of high-lying ligand-centered charge transfer excited states to intersystem crossing.

Three distinctive asymmetric 1,6-enyne cyclization strategies, namely, hydrocyanative cyclization, cyclization/Heck reaction, and cyclization/Heck/hydrocyanation, have been developed, providing a modular synthetic platform for various chiral γ-lactams bearing a quaternary stereogenic center. Furthermore, preliminary mechanistic studies, including DFT calculations, are also conducted.

Substituted allenes without a directing group underwent chromium-catalyzed chemo-, stereo-, and regioselective semihydrogenation with an (alkyl)(amino)carbene-phosphine ligand and a chlorosilane additive. The silylchromium complex formed in situ promotes semihydrogenation through a pathway involving sila-metalation of the allene and β-silyl elimination, with the silyl group acting as a noninnocent ligand to give E-alkene products selectively.

This work represents the first research that employs a combination of solid-state NMR spectroscopy and DFT calculations to clearly elucidate the contribution of electronic structure to the distinct hydrogenation reactivity of bent and linear bimetallic nitrides.

In the NH₃-SCR reaction over V₂O₅-WO₃/TiO₂ catalyst, WO₃ not only serves as an acidic promoter and structural regulator, but also plays a redox role. The WO₃ directly participates in the oxidative activation of NH₃, and hence explicitly exerts a redox effect by forming V–W dinuclear sites with V₂O₅.

It is found that the zinc stripping process is more prone to cause severe side reactions than the deposition process, resulting in the formation of dendrites and “dead zinc.” In this regard, a dynamic molecular protection strategy is proposed to regulate the zinc stripping and deposition processes simultaneously, achieving long-lasting protection of the zinc anodes.

A photo-triggered CRISPR/Cas12a machinery for gene editing is introduced. The machinery is applied for endogenous DNA methyltransferase 1 (DNMT1) gene editing and for in vitro disruption of the hepatocyte growth factor (HGF) gene. The machinery is used for in vivo knockout and disruption of the HGF gene in HepG2 tumors, resulting in effective apoptosis and necrosis of the tumor tissues.

This study introduces an innovative approach to designing self-blown foams by leveraging the irreversible and self-catalyzed transesterification of alkylester which release alcohol gas as blowing agents. The morphology and thermo-mechanical properties of these foams can be precisely tailored by modifying the precursor structure. Remarkably, they can be reprocessed as rigid resins through reversible self-catalyzed transesterification reactions.

A Turing-structured COF membrane with externally striped and internally cavitated architectures is created via the modulation based on metal-polyphenol chemistry. The resulting COF membrane exhibits simultaneously enhanced water permeation and molecular sieving properties, demonstrating its great potential in the separation of high-value pharmaceuticals.

Efficient acidic H₂O₂ electrosynthesis was achieved on F-CNTs with Faradaic efficiency of 95.6% at 1.0 A cm⁻². F-doping regulated the electronic structure, enhanced nanoconfinement effect and oxygen mass transfer of CNTs, leading to a local alkaline microenvironment and promoted *OOH generation for acidic H₂O₂ electrosynthesis.

Targeting Amyloid-β (Aβ) aggregation requires a peptide-based approach that accounts for the structural heterogeneity of Aβ. Here, we employ topological reprogramming via disulfide bonds to stabilize antiparallel β-sheets within the dimeric peptide. This strategy overcomes limitations of linear peptides by creating structured complexes that resist aggregation, offering a novel tactic for tackling AD-related protein aggregation.

Here, we describe the reductive C(sp³)─O bond silylation of ethers with chlorosilanes and magnesium reductants by cooperative rhodium and indium catalysis. This methodology allows the incorporation of silyl moieties into the C(sp³)─O bond of various unactivated cyclic and acyclic alkyl ethers using chlorotriorganosilanes. Not only the mixture of rhodium complex with indium reagent but also rhodium nanoparticles supported on indium oxide showed high catalytic activity, indicating a remarkable cooperative effect by the two metals. Notably, in both cases, the generation of rhodium/indium heterobimetallic alloy nanoparticles was revealed by mechanistic studies including XRD, XAS, and TEM imaging.