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Scientific Perspectives
Scientific Perspectives are written by experts and they outline contemporary scientific best practice in the chemical sciences. For more details, please see the introductory editorial.
Taxonomy of Chemical Bondings: Opportunities and Challenges
- Angewandte Chemie International Edition
-  22 May 2025
Graphical Abstract

The recent focus on supramolecular and nanosized systems produced a major increase in the types of observed noncovalent interactions and in the diversity of terms used to designate them. A hierarchical categorization (taxonomy) of terms used to designate electrophile···nucleophile interactions is proposed here. Core elements of this classification are some recent IUPAC definitions referring to the electrophile.
Guideline for Analysis and Prevention of Contamination Catalysis
- Angewandte Chemie International Edition
-  30 April 2025
Graphical Abstract

Ongoing efforts to discover new catalysts in coupling reactions have provided an effective toolkit for chemists over the last decades. However, metal impurities often lead to costly misinterpretations and reproducibility issues. Our guideline provides a practical roadmap for identifying true catalysts, eliminating impurity-driven errors, and ensuring reliable research outcomes. Designed primarily for handling trace metal challenges, this framework sets a new standard for robust, impurity-free catalyst discovery.
Magnetically Induced Catalysis: Definition, Advances, and Potential
- Angewandte Chemie International Edition
-  18 April 2025
Graphical Abstract

In this scientific perspective, we intend to provide a coherent framework for the field of magnetocatalysis by highlighting opportunities associated with the use of magnetic fields to activate catalysts. A particular focus will be placed on magnetically induced catalysis, providing an overview on current advances and identifying scientific and technical challenges on the path toward a widespread use of this technology in research and industry.
Chemical Process Development in the Pharmaceutical Industry in Europe—Insights and Perspectives from Industry Scientists
- Angewandte Chemie International Edition
-  27 March 2025
Graphical Abstract

What are the tasks of chemical process development in the pharmaceutical industry? What are trends and challenges? This Scientific Perspective written by members of the European pharmaceutical industry introduces key concepts of drug development and key drivers for the future of chemical process development.
Revisiting Photocatalytic CO2 Reduction to Methanol: A Perspective Focusing on Metal-Organic Frameworks
- Angewandte Chemie International Edition
-  21 February 2025
Graphical Abstract

Photocatalytic CO2 reduction to CH3OH, particularly using metal-organic framework (MOF) photocatalyst, has received considerable attention due to its long-term potential to harness sunlight for converting CO2 into this valuable fuel. This Perspective outlines the best practices that to provide robust and convincing evidence that CO2 is the source of CH3OH in the photocatalytic reactions.