Ning et al., have reported a very interesting and promising electrochemical method of 1,4-NADH regeneration. The only part of this article that seems to be disputable is the reported mass spectrometry data, namely, the lack of specification of the employed LC-MS conditions, sometimes the wrong m/z values assigned to the species claimed to be identified, and the lack of the mass spectra of NADH.

Visible light-driven photochemistry has advanced significantly, offering diverse methodologies in synthetic organic chemistry. Photocatalysis using red and near-infrared (NIR) light is particularly notable due to its lower energy, reduced phototoxicity, minimized side reactions, and deeper penetration into reaction media. This minireview summarizes recent developments in red- and NIR-mediated photocatalysis, emphasizing radical generation and reactive intermediates for organic synthesis. Applications in small-molecule activation, polymer chemistry, and biologically relevant transformations are discussed, highlighting the growing potential of these photochemical processes in fundamental and applied chemistry.

This Minireview offers a comprehensive overview of Type-I photodynamic therapy and outlines two design strategies for Type-I photodynamic agents: thermodynamic modulation through molecular engineering to block Type-II excitation energy transfer, and kinetic optimization of photoinduced electron/hydrogen transfer processes to enhance Type-I pathway.

Porous conductive ion-selective membranes (PCIMs) enable low-resistance, high-selectivity ion transport in sustainable energy devices. This review explores emerging PCIMs with sub-nano/nanometer pores, focusing on ion transport mechanisms, key pore characteristics, and design strategies. It also highlights advances in PCIM applications, including fuel cells, flow batteries, and Li—S batteries. By integrating theory with design principles, this review provides insights for optimizing PCIMs and advancing membrane-based energy technologies.

There are two significant factors necessary for the cathode materials of aqueous Mg-ion energy storage devices as follows: one is the storage mechanism of Mg²⁺ that can achieve enhanced Mg²⁺ diffusion kinetics and bring higher power density; the other is the high structural stability to achieve long lifespan. The tetrahedral vacancy reversible insertion/extraction mechanism by Mn(II) dissolution and optimize the integrity of the spinel framework is a powerful strategy to achieve Mg²⁺ energy storage system with high rate performance and long lifespan.

Resonance Raman spectroscopy (RRS) was used to observe the in situ CO₂ electroreduction process by designing copper electrodes with unique structures. This dynamic observation allowed for the capture of the C─C coupling process, where CH₂ asymmetrically couples with CO to form CH₂CO.

Visible light/pH dual-responsive ultrathin polymersomes (UTPSs) with reversible stimuli-chromic characteristics were fabricated through self-assembly of side-chain-type amphiphilic alternating azocopolymers, displaying reversible shape transitions, repeatable acidochromism from yellow to pink, and fluorochromism performance. The proof-of-concept multilevel-decrypted 2D QR code using dual-responsive UTPSs into patterning lithography proved the potential on multiple information encryption.

A tetrathiafulvalene-based reactive mesogen (TRM) is used to develop a TRM polymer matrix (TPM) with excellent thermal conductivity and interfacial affinity with boron nitride (BN) and expanded graphite (EG). Fabricated TPM composites, which are thermally and chemically stable, can be selectively used for electrical insulation, conduction, and electromagnetic interference (EMI) shielding.

A rare sequence-selective terpolymerisation of elemental sulphur, aromatic thioanhydrides, and epoxides yields dynamic poly(ester-alt-S_x) polymers. Mechanistic insights reveal a lithium-catalysed rate enhancement via ester coordination. The resulting polymers are thermally stable, backbone-editable, and processable into degradable adhesives.

A catalyst composed of Cu₄ clusters and adjacent Cu single atoms anchored on carbon nitride was prepared via a two-step calcination process. The synergistic effect between Cu₄ clusters and Cu single atoms could lower the C─C coupling energy barrier and make it one of the most efficient catalysts for CO₂ to ethanol via photocatalysis.

Hydration-shielding accelerated self-catalytic polymerization (HS-A-RP) method was first developed for implementing the fast preparation of robust polyzwitterionic hydrogels (PZHs) without external energy at low monomer concentration. HS-A-RP shows attractive applications in scalable manufacture of PZHs coatings on diverse substrates, in situ encapsulation of thermally sensitive materials, as well as excellent sand fixation ability.

This report explores polaron-based charge transport in controllably p-type doped 2D polymers. Substoichiometric injection of holes in 2DP lattices leads to the lowest optical bandgaps and maximal electronic conductivities. Variable-temperature conductivity reveals the existence of hopping-type transport with two distinct Arrhenius regimes, which may be related to in-plane and cross-plane directional electronic transport.

In this work, two benzothioxanthene imide dyes demonstrate excellent photochemical properties. When used as photocatalysts, they work with amine and iodonium salt or sulfonium salt to form different three-component systems for effectively initiating photopolymerization under visible light, through photoredox catalysis processes. The best formulations can be applied for 3D printing and direct laser write. This work offers a strategy for developing novel photosensitive dyes as photocatalysts.

Cation vacancies-rich, 1 nm-thick □-H_xIrO_y nanosheets with both high catalytic activity and high protonic conductivity have been prepared. This bifunction integration enables the fabrication of a low-iridium-loading, low-ionomer-dependent catalyst/ionomer layer for efficient proton exchange membrane water electrolysis.

Dual-functional TiO₂/CdSe/NFPP cathode was designed for photorechargeable sodium batteries. Photogenerated holes from CdSe migrate to NFPP, facilitating efficient sodium deintercalation. The holes-absorbed film-forming agent FEC on NFPP causes a thin NaF-rich cathode electrolyte interphase, which effectively suppresses electron tunneling and electrolyte decomposition. The PRSBs deliver high capacity and conversion efficiency (4.34%).

A composite solid-state electrolyte with multivariate distribution anisotropic structure was developed. Parts of the vermiculite sheets suspended among the PVDF matrix facilitate lithium salts dissociation and form fast Li⁺ transport channels. Other parts of vermiculite sheets tiled on electrolyte surface generate dense and high-modulus Li₂SiO₃-rich solid electrolyte interphase, improving the interfacial kinetics and suppressing the dendrite growth.

A comprehensive understanding of the concurrent capacity and stability enhancement mechanisms attributed to Nb-doping and highlights the significant potential of the synergistic regulation of mechanical and chemical coupling in improving the capacity and lifespan of NRLOs by Nb-doping.

An artificial intelligence platform, namely Uni-Electrolyte, was constructed to design electrolyte molecules for rechargeable batteries. The Uni-Electrolyte includes three parts, i.e., EMolCurator, EMolForger, and EMolNetKnittor, which can design new molecules, predict their retrosynthesis pathways and reaction conditions, and predict the chemical mechanism to produce a solid electrolyte interphase, respectively.

Electrochemically charging colloidal nanocrystals (NCs) enables the study of the intrinsic multi-carrier dynamics in quantum dots (QDs) by in situ ultrafast time-resolved spectroscopy, revealing the spin blockade effect and phonon bottleneck effect for hot electron cooling and allowing mechanism studies of charged QDs in various applications.

The uniformly dispersed Cu single atoms on the In₂O₃ enable efficient photothermal CO₂ conversion through modulating the synergy with induced oxygen vacancies. The catalyst exhibits an optimal reactivity (1108 mmol g_cat⁻¹ h⁻¹ CO with selectivity >99%) at a moderate Cu loading (2.4 wt%).

Human H ferritin (HuHf) is a nanocarrier for anticancer metal drugs. By cryo-EM, a 1.51 Å structure of its adduct with Au(NHC)Cl was solved, showing a novel tetranuclear gold(I) cluster bound to Cys90 and Cys102. Short inter-metal distances indicate aurophilic interactions. This study highlights the power of cryo-EM in examining metal-drug–protein interactions using the strong signal of transition metal ions.

Dendrimer nanogels are designed by emulsion-free method, endowing them with dual-active groups, o-hydroxyl amine, temperature-responsiveness, polyampholyte property, and self-triggered aminolysis. With these unique characters, dendrimer nanogels display high gene transfection and therapeutic efficacies with low side effects, thus solving the dilemma between efficacy and cytotoxicity of conventional cationic colloidal vectorsin gene delivery.

Here we report flexible, two-dimensional polyphthalocyanine-crown-ether frameworks coating on carbon nanotubes, which not only serve as supramolecularly confined catalysts in lithium–sulfur chemistry but also suppress the growth of lithium dendrites. This newly designed catalysts achieve the long-term cycling operation of lithium–sulfur batteries with a tiny capacity decay rate of 0.711‰ per cycle. Our design strategy can be potentially applied to a wider spectrum of electrochemical catalysis.

A novel H₂S donor functionalized molecular machine, ACR-DM-HS, with combination of antibacteria and anti-inflammation to accelerate angiogenesis through membrane disruption, ROS generation, and H₂S releasing was developed for synergistic therapy of multiple resistant bacteria-infected chronic wound, which offers a promising treatment approach for combating bacterial multidrug resistance and tackling chronic wounds.

The spin-orbit (SO) splitting of the superatomic 1P orbitals in thiolate-protected Au₁₃ superatoms were investigated. Cryogenic anion photoelectron spectroscopy and fully relativistic calculation including SO coupling revealed the 1P orbitals of the Au₁₃ and Au@Ag₁₂ superatomic cores undergo SO splitting, while not in the Ag₁₃ core.

l-Citrulline (CIT), with amino acid end groups (─COOH, ─NH₂) and a urea end group (─NH─CO─NH₂), functions as a molecular bridge to modulate the SnO₂/perovskite buried interface. The optimized PSC device (0.07065 cm²) achieved an impressive champion PCE of 25.95%. The solar module with an active area of 23.26 cm² achieved a PCE of 22.70%, which is one of the highest values reported recently using the slot-die coating method. The strategy offers valuable insights to advance the industrialization of large-area devices.

The table of contents (TOC) figure provides a visual overview of the key innovations and findings of this study on high-voltage lithium metal batteries (LMBs). The single-solvent electrolyte composed of 2.3 M lithium salt in tris(2,2,2-trifluoroethyl)phosphate (TFEP), which enables stable LMB operation at ultra-high voltages up to 5.0 V. The electrolyte forms large weakly-solvating nanometric aggregates (n-AGG), which contribute to enhanced oxidative stability and facilitate efficient redox reactions. Notably, the electrolyte exhibits exceptional cycling stability for over 1500 h, effectively suppressing dendrite formation and demonstrating strong compatibility with high-voltage cathodes, such as NCM811 and LiNi_0.5Mn_1.5O₄ (LNMO). The improved thermodynamic and kinetic stability of the electrolyte significantly enhances the high-voltage tolerance and cycling performance of LMBs, offering promising prospects for the development of next-generation energy storage technologies.

Evaluating the synergetic effect of dielectric constant (DC) and binding energy (E_a) of solvents on the interaction between Na⁺ and anion balances stable interfacial chemistry and high ionic conductivity in non-flammable phosphate electrolytes. Developed electrolytes enable high-energy pouch cell achieving a capacity retention of 87.1% after 700 cycles at the current density of 2C.

We disclosed a palladium-catalyzed tandem radical Heck/allylic amination of α-bromoamides with 1,3-butadienes and enynes at room temperature to yield γ-lactams. Unlike previous alkyl Heck reactions, this transformation generates hybrid alkyl Pd(I)-radical and a transposed π-allyl Pd(I)-radical under ambient conditions.

[Au₆Cu₂(C₂C₆H₄X)₆(PPh₂C₆H₄PPh₂)₃]²⁺ (X = NO_2, denoted as NO₂-Au₆Cu₂; X = H, denoted as H-Au₆Cu₂) clusters were synthesized for radiosensitizing studies. The NO₂-Au₆Cu₂ nanoparticles demonstrated significantly enhanced radiosensitization compared to the H-Au₆Cu₂ nanoparticles, attributed to their higher electron affinity, which increases hypoxic cytotoxicity and mimics the oxygen effect by reacting with DNA free radicals.

This study reveals that sulfur doping in FeN₂O₂ single-atom carbon dots induces a proton driving mechanism, significantly enhancing peroxidase-like activity. This mechanism facilitates H₂O dissociation and proton transfer, providing an ample supply of H* for the conversion of H₂O₂ to·OH, as verified through KIE, in situ experiments, and DFT calculations.

Interrupted Dowd–Beckwith (IDB) reaction enables the highly regioselective deconstructive functionalization of cyclic ketones using electricity as the sole oxidant. This strategy transforms complex cyclic ketones into acyclic molecules and has been applied to the asymmetric synthesis of planococcol, citrilol acetate, maconelliol, and its derivatives. Mechanistic studies support an oxidative radical-polar crossover.

A new ionic quinoline-linked COF (iQCOF) was synthesized by combining π-bridge and charge-introduction strategy via a one-pot Povarov reaction. The π-bridge-linked ionic liquid endow iQCOF enhanced charge transfer ability, fast ionic atmosphere dissociation rate, and higher reaction rate. Thereby, it can be regarded as advanced COF-based cathodes with rapid kinetics to achieve high-rate performance and long-term stability.

By incorporating four O─B←N units into naphthalene diimide, the core is transformed from an aromatic form to a quinoidal form, significantly enhancing π-electron delocalization. This results in a reduced bandgap from 3.10 to 0.88 eV and a redshift in absorption from 400 to 1410 nm. The synthesized polycyclic aromatic hydrocarbon exhibits strong SWIR absorption and high transparency in the visible region, developing a colorless anti-counterfeiting application.

The photocatalytic coupling reaction of carbon monoxide and ammonia pays a new pathway for urea synthesis under mild conditions. Herein, we proposed a universal O₂-mediated urea generation pathway via the O₂^•– radicals act as the dominant active species to drive the mild NH₃ oxidation to •NH₂ radicals, which then coupled with CO as the crucial step for urea production.

Electrochemical acetylene hydrodimerization mechanisms are deciphered by correlating the nuclearity of Cu site in Cu-MOFs with catalytic performance. The neighboring Cu dual sites in trinuclear Cu₃-MOF orchestrate three critical steps: acetylene adsorption, C–C coupling of *C₂H₂ and *C₂H₃ intermediates, and 1,3-butadiene desorption, which contribute to the superior electrocatalytic selectivity of 1,3-butadiene.

The dynamically changing hydrogen bonding between the enamine radical cation and cobaloxime controls the enantioselectivity.

Fluorination-assisted interfacial dipole engineering is conducted for inorganic CsPbI₃ PSCs, which could not only form more robust interfacial contact but also beneficial dipole alignment, leading to effective passivation and prominent energy level adjustment with additional charge transport channels, thus substantially suppressing interfacial energy losses. Consequently, the PSCs show an efficiency of up to 22.05% with superior device stability.

Multiplexed quantification of small-molecule binding kinetics to virion-displayed membrane proteins via charge-sensitive, wide-field plasmonic imaging of barcoded nanocomposite oscillators. Virion display maintains native membrane protein environments. Affinity-resolved multistate DNA barcoding efficiently addresses individual nano-oscillators and enables measurement of a library of G protein-coupled receptors on a single chip.

A heterogeneous catalyst Cu/UiO-66-NH₂-A with atomic Cu–O–Zr sites was successfully developed at ambient temperature and pressure, which not only exhibits efficient activation of C═O and H─H bonds but also possesses a fast hydrogen spillover effect. These properties endow this catalyst with superior catalytic activity for the upcycling of waste PET and CO₂ into p-xylene (PX) and ethylene glycol (EG).

C–H functionalization of polyolefins in a solvent-swollen semicrystalline state favored selectivity for blocky microstructures. Blocky microstructures preserved the crystallinity size, percent, and strength of polyolefins in comparison to their random analogues.

Through a strategic combination of sulfo-functionalized ligands and terephthalic acid, UiO-66-based catalysts with tunable Lewis acidity were synthesized, where the specific chemical state of each sulfo group served as a critical regulator of catalytic activity in glucose isomerization. This precise control enabled unambiguous correlation between acid site characteristics and reaction performance.

A novel gasphilic Cu₂O nanoparticle dispersed within the hierarchically porous carbon matrix as a high-efficiency CO₂RR electrocatalyst switches in the reaction pathways from ethanol to ethylene during CO₂RR at ampere-level current, depending on the multiscale microenvironment engineering. The Faradaic efficiency (FE) of ethylene achieved is as high as ∼71% with a partial current density of 513.6 mA cm⁻².

This study reports an unusual phenomenon of pollutant-induced activity enhancement of CuO for H₂O₂ activation and self-accelerated pollutant degradation, contrasting the performance decay of Fe₂O₃ catalyst. CuO can stabilize and activate phenol via ligand-to-metal charge transfer, generating surface-bound phenoxyl radicals to further mediate the H₂O₂ activation and meanwhile yielding low-valent Cu. This offers opportunities for simultaneously addressing the catalyst passivation and redox cycling limitations of heterogeneous Fenton-like catalysis.

Hexafluoroisopropanol (HFIP)—a polar alcoholic solvent that has been underutilized in allylboration—enables otherwise challenging (E)-selective crotylboration of enantioenriched quaternary α-silyl crotylboronates with aldehydes. HFIP's strong hydrogen bonding effect increases the Lewis acidity of the boron center and the steric effect of Bpin, resulting in high yields and (E)-selectivity.

Enantioselective immobilization of chiral Co(salen) complexes on the surface of chiral β-ketoenamine-linked COFs enables axial coordination of Co(II) centers with COF linkages, which tautomerize from keto-enamine to enol-imine upon binding. This enantiomeric assembly enhances Co(II) reducibility and allows for inner-sphere electron transfer, leading to remarkable photocatalytic H₂ evolution without additional precious metals.

Tuning the polarity of imine (C═N) bonds in donor–acceptor covalent organic frameworks (COFs) with fluorinated units balances exciton binding and charge separation. A moderate C═N polarity delivers optimal H₂ evolution (14.0 mmol h⁻¹ g⁻¹), offering insights into polarity–performance relationships in COF photocatalysts.

Asymmetric Cu_F-Cu_N motifs were engineered through the in situ isostructural substitution method on F-Cu₃N substrates. Unlike the isolated 3d_z²-2p_z σ bonding between Cu_N and the *C₁ intermediate, Cu_F establishes an additional 3d_xz-2p_z π back bonding interaction. This synergy induces a charge-polarized 2*CHO adsorption configuration, concurrently enhancing coupling kinetics and C₂ selectivity through dipole-dipole interactions.

This work demonstrates the occurrence of electronically asynchronous transition state in oxygen atom transfer (OAT) reaction by Cu^II–NO₂⁻ complexes (1−4) controlled from remote site. OAT reactivity was found to be linearly correlated with  β-LUMO and Cu(II)/(I) redox potentials, which were tuned from remote site substituents. Mechanistic study indicates asynchronous electron transfer mechanism where Cu^II/I reduction precedes nitrite reduction.

2,6-Dimethylpiperidine disuccinimidyl tridecanoate (DPST), an enrichable and quantifiable cross-linker, offers the advantages of membrane permeability and biocompatibility. It enables one-step enrichment of cross-linked peptides via tandem mass tag (TMT) antibody, minimizing sample loss and enabling in vivo cross-linking mass spectrometry (XL-MS) analysis of 1E4 cells. The isotope labeling feature of DPST ensures precise quantification in dynamic environments. With its flexible design supporting various isotope labeling configurations (6/10-plex), DPST holds significant promise for advancing biomedical research.

Triplet-triplet annihilation-based photon up-conversion (TTA-UC) system using an anthracene-based UC emission by assembling multiple chromophores linked to a boron to enhance TTA rate constant. Structural fluctuations driven by vibronic motion induce picosecond intramolecular triplet exciton hopping, expanding the triplet exciton distribution and enhancing intermolecular TTA reactivity.

A new class of supramolecular antimicrobials was developed by forming host-guest inclusion complexes between conjugated oligoelectrolytes (COEs) and cyclodextrins. This supramolecular strategy enhanced COEs' biocompatibility without sacrificing antimicrobial efficacy, offering a new antibiotic design platform to address the typical trade-off between efficacy and selectivity in amphiphilic antimicrobials and combat antimicrobial resistance.

Functional liquid coordination polymers near ambient conditions are prepared by introducing H₃PO₄ as a network modifier. This process disrupts extended coordination networks, producing a stable liquid. Liquid properties are controlled by tuning the ratio of network modifiers, resulting in anhydrous proton conductivity up to 27 mS cm⁻¹ at 353 K and viscosities ranging from 18.8 to 10^5.9 Pa·s at 303 K.

This study presents the condensate formation from engineered amphiphilic-branched peptides in living cells through enzymatic reactions. We describe the rational design and synthesis of DMN-SIPL, a peptide that forms solid-like condensates via liquid–liquid phase separation (LLPS) when triggered by the type-II membrane-associated serine peptidase hepsin.

In situ KPFM reveals charge-transfer mechanism in CdS/BiOBr S-scheme heterojunctions. Upon light illumination, the Fermi level (E_f) of n-type semiconductors rises, generating a built-in electric field that drives photogenerated carrier separation. Electrons accumulate on CdS, lowering its surface photovoltage (SPV), while holes accumulate on BiOBr, elevating its SPV above that of the bare semiconductors, highlighting efficient charge separation.

In this work, we report the synthesis of two robust, mesoporous metal-organic cages or polyhedra (MOCs/MOPs) using an isoreticular expansion approach. Among them, the largest mesoporous MOP captures up to 0.47 g_water·g_MOP⁻¹, displaying an S-shaped water sorption isotherm with a hysteresis loop.

A feasible asymmetric ligand substitution strategy is developed to break symmetric sites on metal-organic frameworks (MOFs). The obtained defective MIL-101 (D-MIL-101) as a nanozyme featured with asymmetric Fe^3-δ/Fe³⁺ sites exhibits high performance for photocatalytic depolymerization of polyester plastics.

A platinum-mediated assembly has been used to synthesize a phenylene cage with a diameter of 2.0 nm. The strained nanocage exhibits intense blue emission and piezofluorochromism, with the fluorescence shifted from blue to yellow–green under pressure.

This manuscript describes the development of proteomimetic molecular glues. We show that crosslinked helix dimers can be designed to recognize two different proteins. We converted a Ras ligand into a Ras degrader by epitope grafting, an MDM2 E3 ligase binding domain solvent-exposed surface of the dimeric scaffold.

Through steric modification of PTZ dyes, we developed a nonconjugated structural distortion strategy that enhances ISC efficiency and prolongs triplet-state lifetime via optimized spin–orbit coupling. The optimized photosensitizer HNBS achieves oxygen-independent tumor ablation at ultralow doses while inducing pyroptosis-mediated immunogenic cell death for synergistic photoimmunotherapy.

A universal p-type heterointerface between SAMs and perovskite was constructed using the heterocyclic dipolar compound imidazole hydroiodide (ImHI), enabling effective hole extraction from perovskite to SAMs and significantly reducing charge recombination. As a result, the optimized solar cells reached 26.05% and demonstrated excellent stability.

By precisely controlling Al³⁺ concentration in SrCl₂ molten salt through the addition of miscible AlCl₃, the anisotropic SrTiO₃ single crystals with well-defined {100}, {111}, and {110} facets can be sequentially synthesized, achieving the optimal remarkable hydrogen evolution rate of 2621.85 µmol·h⁻¹ and apparent quantum yield value of 50.5% at 350 nm for stoichiometric photocatalytic overall water splitting.

Atomic-level investigation of V(V) solvation transformation from [VO₂(H₂O)₃]⁺ to VO(OH)₃ via a four-step mechanism is presented, with the second deprotonation as the rate-determining step. This insight enables V(V) stabilization via proton and anion coordination, and a mixed-acid electrolyte was developed with exceptional stability at 50 °C for VFB.

In alkaline seawater, ruthenium clusters in nitrogen-doped molybdenum carbide (Ru@NMoC) act as highly efficient catalysts to promote the hydrogen evolution reaction (HER). Theoretical calculations and X-ray absorption spectroscopy reveal that nitrogen doping induces electron redistribution around the Ru clusters, optimizing their electronic structure. This enhances the adsorption and desorption of intermediates, accelerating the HER kinetics.

We developed a palladium-catalyzed system for P(III)-directed C─H activation of aminophosphines and cyclization with alkynes facilitated by deprotonative isomerization, using phosphonium salts as key additives. These salts lower energy barriers, regenerate the catalyst, and protect the P(III) group, enabling stereospecific synthesis of chiral phosphacycles.

We report a rigid SAM (PhPAPy), designed to leverage the structural tunability of SAMs for achieving uniform substrate coverage with a single molecule. The high-quality HTL based on PhPAPy effectively minimizes direct perovskite–electrode contact, reduces defect density, and suppresses nonradiative recombination at the buried interface. The champion device achieved a certified reverse-scan PCE of 26.74% while maintaining T₉₅ = 2000 h long-term stability (ISOS-L-2).

A recyclable “polyiodide reservoir”, engineered by the nitrogen-active site densities within covalent organic cages, is proposed as the iodine host. The resulting zinc–iodine battery demonstrates a capacity retention of 90.1% after 4000 cycles at 5 C and maintains 85.4% of its initial capacity after three reuse cycles.

Utilizing “host−guest recognition followed by click polymerization” strategy, a Type I-B main-chain polyrotaxane (PR), featuring multiple wheels and stoppers along the polymer backbone, was efficiently synthesized. The first-ever Type I-B main-chain PR network (PRN) was then constructed to unveil the structure−property relationships of the PR. The special topological structures and dynamic characteristics of the PR skeleton provided multiple energy dissipation pathways, effectively toughening and strengthening the PRN.

Structural shaping of a highly reactive chiral Mn-oxo species translates into exceptionally enantioselective C─H oxidation catalyst of cyclohexyl 1,3-meso diethers (up to >99% ee) leading to polyfunctionalized cyclohexanes.

The first catalytic asymmetric (4 + 4) and (4 + 4 + m) cycloadditions of 2-indolylacetates have been established via asymmetric organocatalysis, providing a useful protocol for constructing enantioenriched indole-fused medium- and large-sized rings. The biological evaluation of selected chiral indole products discovered several compounds with some extent of antitumor activity, indicating their potential applications in medicinal chemistry.

Supramolecular chalcogen-bonded liquid crystal elastomers incorporating Se⋯N interactions exhibit distinct shape memory and actuation properties. Stronger Se⋯N ChBs enable programmable one-way and two-way SME, while weaker S⋯N ChBs fail to induce actuation. Solid-state NMR, Raman spectroscopy, and DFT reveal the molecular interactions governing ChB-driven mechanical responses.

A synergistic photocatalysis–electrocatalysis system addresses the I₃⁻ light shielding in HI splitting and achieves efficient H₂ generation and energy-saving benzylamine oxidative upgrading. The Re_0.5Mo_0.5S₂-modified MAPbI₃ photocatalyst generates 875.4 µmol of H₂ in 4 h, and the electrocatalytic I₃⁻ reduction coupled with benzylamine oxidation can operate at a low potential of 0.44 V for 10 mA cm⁻².

The functionality of crystalline organic frameworks incorporating dative B←N and reversible B─O bonds (BNOFs) is engineered by introducing diverse dangling groups. Notably, the carboxyl-functionalized BNOF-5 exhibits superior reversible NH₃ adsorption compared with their less- or nonfunctionalized counterparts. Combining high surface areas, low cost, and exceptional sustainability, these functionalized frameworks represent a promising platform for advanced applications.

Surface hydroxyl modification on noble-metal-free photocatalysts enhances CH₄ chemisorption, reducing the energy barrier for C─C coupling and effectively suppressing over-oxidation to CO₂, thereby achieving approximately 97% selectivity over a 200-h flow operation.

A multifunctional interfacial layer of layered-spinel heterogeneous structure and oxygen vacancies was formed on the surface of LRMOs, which improved the structural stability and the reversibility of anion redox reaction. The treated cathode features high initial capacity of 314.5 mAh g⁻¹ with a coulombic efficiency of 88.3%. When cycling at 1 C, the cathode shows a high capacity retention of 87.9% with a small voltage decay of 1.26 mV per cycle.

A paired electrolysis system for simultaneous glycolic acid production was constructed through combining anodic oxidation of polyethylene terephthalate hydrolysate and cathodic reduction of biomass-derived oxalic acid, which was enabled by the rational design of a CO-tolerant PdBi alloy anode and an earth-abundant TiO₂ cathode.

A molecularly woven artificial solid electrolyte interphase (SEI) was constructed by coating woven polymer crystals onto the Li metal anode. The mechanical stability of these woven polymer crystals, combined with their intrinsic Li-ion channels, enables the resulting lithium-metal batteries to be dendrite-free and long-life.

A unique regulation mechanism of reactive oxygen was proposed for selectively photocatalytic conversion of methane to methanol under mild conditions. This new mechanism addresses the contradiction between activity and selectivity faced with the traditional uncontrolled generation of reactive oxygen species by regulating the interaction between active centers and key intermediate.

Structural interpretation and molecular dynamics simulations reveal how molecular moieties and interaction networks influence the π–π stacking structures and conformational states of lignin during dissolution and aggregation: laterally shifted in deep eutectic solvents, offset-stacked in tetrahydrofuran, and stretched in dimethyl sulfoxide.

Light-responsive supramolecular (SM) materials are attractive for many applications but are difficult to achieve. Here, we report a systems approach that involves blending a hydrogen-bonded SM network with a photoacid generator. The resulting material displays significant softening upon UV irradiation and functions as an efficient debonding-on-demand adhesive.

An ionic conductive elastomeric electrolyte rich in high-density hydrogen bond network was constructed through the cross-linked encapsulation of PA molecules with PVA chains during solvent evaporation. Unlike the conventional hydrogel electrolytes, elastomeric electrolytes (ZICE-4) demonstrate the fast Zn²⁺ ion transport, uniform Zn²⁺ flux, high volumetric adaptability, and wide working temperature range.

Both hydrogen-bond acceptor basicity (β) and the energy level gap between the lowest unoccupied and the highest occupied molecular orbital (HOMO-LUMO gap) of solvents are identified as the top two parameters impacting CE by machine learning. A regression model is further proposed to estimate the CE based on β and HOMO-LUMO gap, which provides a reliable interpretable quantitative model for rational electrolyte design.

MgF₂ coating with high coating integrity is in situ constructed on Si nanoparticles. During electrochemical cycling, the MgF₂ layer undergoes in situ conversion into LiF and Mg, thereby forming a robust solid electrolyte interphase (SEI) with high mechanical adaptability, excellent electronic insulation, and high ionic conductivity. This unique transformed SEI layer effectively mitigates mechanical degradation and interfacial side reactions, contributing to significantly enhanced electrochemical properties of the Si anode.

By engineering the intermediate layer of lanthanide nanoparticles, we achieve switchable NIR-II emissions, enabling high-resolution vascular imaging at 1525 nm and deep bioorthogonal liver tumor imaging at 1064 nm. This will provide reference for designing imaging probes to adapt to fluorescence imaging in different scenes.

A green interfacial polymerization platform that can eliminate side reactions was designed to precisely regulate the preparation of narrow pore size polyamide membranes through a dynamic 3D hydrogen bonding network. In addition, the platform has unprecedented universality, and the membranes produced have an order of magnitude higher selectivity for NaCl/Na₂SO₄, as well as excellent permeability.

We presented the rational design and synthesis of two β-ketoenamine-linked COFs engineered with high-density nitrogen/oxygen active sites for selective gold recovery. Their comprehensive gold recovery performance is among the best in the COF field, with the third highest adsorption capacity, ultrafast adsorption kinetics, and near-perfect selectivity, resulting from the synergistic effect of redox interactions, electrostatic interactions, coordination bonds, and hydrogen bonding.

The first application of a neutral anion receptor as a “single-molecule carrier” for targeted delivery of phosphonate drugs into living cells through anion coordination.

A feasible ether-based electrolyte incorporating methylmagnesium chloride as a Lewis-basic additive is proposed to regulate interfacial chemistry. This electrolyte plays a crucial role in promoting a robust solid-electrolyte interphase formation and enhancing Li deposition, achieved through the bifunctional effects of anion-additive interactions. The designed electrolyte contributes to the superior cycling stability of Li metal anodes.

This manuscript demonstrates the copolymerization of Se/CO/OX to yield the well-defined poly(selenocarbonate) that can be easily converted into the poly(selenoether) via the O/Se exchange reaction.

A direct synthesis strategy was used to prepare branched Pd₁Co₂P_x nanostructures with rich Pd─Co─P interface sites, demonstrating their efficacy as cathode catalysts for lithium–oxygen batteries (LOBs). The Pd─Co─P interfaces can direct the two-dimensional growth of Li₂O₂, thereby facilitating the formation of more easily decomposable film-like Li₂O₂ products, which enhances the stability of LOB cycling.

In a model Mukaiyama aldol reaction with unbiased substrates, high enantioselectivity was achieved with a modifiable bidentate iodine(I)-based halogen bonding organocatalyst. The crucial role of halogen bonding was confirmed by the low performance of the corresponding hydrogen bond donor and via DFT calculations.