Kawamata, Baran, and Shenvi disclose a solitary iron-catalyzed conceptually distinct platform for constructing quaternary carbons using readily available and structurally diverse redox-active esters (RAEs) and olefins as modular coupling fragments. The heteroselective radical quaternization exhibits appreciable functional group tolerance and enables the synthesis of a palette of quaternary carbon-containing molecules under practical conditions.

The ESR spectra reported in a Research Article by Chao and co-workers are not in agreement with reactive “carbon radicals” claimed to be produced by 730 nm irradiation of the iridium(III) complex Ir4-red. The observed tumor-damaging effects must be induced by other, unidentified reactive intermediates.

Key roles for fluorometallacycles in first row metal complex-catalyzed reactions are summarized and several future prospects identified.

DNA tetrahedral frameworks find diverse applications as functional constituents for operating dynamic networks, directing crystalline assembly, switchable biocatalysis, and medicine uses including sensing, and stimuli responsive drug carriers.

A spontaneous cascade optimization strategy is reported firstly to regulate Zn²⁺ migration-diffusion behavior. A separation-reconstruction layer is constructed on the Zn anode. The soluble components can be separated into the electrolyte for primary optimization, and the poor-soluble components are reconstructed into flower-like arrays for secondary optimization. This strategy realizes the overall improvement of Zn ion battery performance.

A selective catalysis anionic decomposition strategy for Li metal anode is reported by charge-separated TP-COF. The strong adsorption between TP-COF and FSI⁻ lowers the lowest unoccupied molecular orbital (LUMO) energy level of FSI⁻, accelerating the decomposition of FSI⁻ and generating a stable LiF-rich SEI. Consequently, dendrite-free lithium deposition and high-energy-density lithium metal batteries were achieved under realistic conditions.

A HOF-based novel solid-state electrolyte was constructed by taking advantage of the abundant multisite hydrogen bonding and stabilizing π–π stacking interactions in HOF-DAT. Benefiting from the abundant C=O groups in the HOF backbone as ion hopping sites and the flexible hydrogen bonding skeleton of LHOF-DAT SSEs, a fast Li⁺ ion conductivity (2.2×10⁻⁴ S cm⁻¹), a high Li⁺ transference number (0.88), and a wide electrochemical window of 5.05 V were achieved.

The first example of using a molecular mediator in the catalytic oxidation of ammonia to N₂ is reported. An iron electrocatalyst bearing a macrocyclic ligand with four N-heterocyclic carbene (NHC) donors functions at low temperatures (−30 °C) and retains high reactivity even at extremely low loadings (approximately 0.043 mM; 0.004 mol %) of the Fe catalyst.

A rationally selected methyl nonafluorobutyl ether (M3) diluent is introduced into the N,N-dimethylacetamide (DMA)-based electrolyte to construct a localized high concentration electrolyte. The interaction between the DMA solvent and M3 diluent increases the coordination number of Li⁺-anions, facilitating the formation of an anion-derived inorganic-rich solid electrolyte interphase to improve the Li metal stability and consequently realizing stable and high-performance Li−O₂ batteries.

This research article presents two new benign methodologies to access reactive and soluble lignin-based polyamines. The aminated lignin products have potential as renewable building blocks in aromatic polymeric materials or as potential chelating, antibacterial agents, for instance.

Dearomative construction of triply-fused 2D/3D frameworks was achieved from quinolines via nucleophilic addition and borate-mediated photocycloaddition in a chemo-, regio-, diastereo-, and enantioselective manner. The borate complex accelerates the photocycloaddition and suppresses rearomatization in the excited state. Based on mechanistic analysis, further photoinduced cycloadditions affording other types of 2D/3D frameworks from isoquinoline and phenanthrene are also developed.

Electrochemical impedance spectroscopy interpretation is essential for comprehending the electrochemical processes in porous electrodes. This work demonstrates that the high-frequency impedance arc is attributed to the ion transport resistance in pore channels and solid electrolyte interphase, while the mid-frequency capacitive behavior results from a series connection of electrical double layer capacitance and pseudo-capacitance.

The unique cascaded dual-cavity boride nanoreactor is rationally designed as a sulfur host, which achieves controlled catalysis in the heterogeneous catalytic system of lithium-sulfur batteries. The coupling between atoms regulates catalyst activity and suppresses Li₂S passivation. The mechanism and application investigation of nanoreactor provides a guiding strategy for lithium-sulfur batteries.

Ru/In₂O₃-ZrO₂ was found to be active for ethanol production from CO₂ hydrogenation, but ethanol productivity decreased substantially after several hours of reaction due to the excessive reduction of In species. With the addition of steam as a mild oxidant and using porous polymer layers to control In mobility, Ru−In₂O₃ interface sites were stabilized, and ethanol could be produced with superior overall selectivity (70 %, rest CO).

The alkaline HOR performance of ruthenium-based phosphides were explored to investigate the catalytic role of phosphorus. P-species induced orbital overlap and d-band structure regulation would optimally enhance the hydroxyl binding energy under moderate P-content, which increase the proportion of strongly hydrogen-bonded water with improved connectivity of hydrogen-bond network and subsequently boost the HOR kinetics.

A transistor-based DNA molecular computing platform that is capable of simultaneously detecting multiple microRNAs and rapidly providing diagnostic results through built-in logic computing. The platform enables both accurate and efficient diagnosis of cancers, showing great potential in precision medicine and personalized therapy.

A novel double-layer strategy to functionalize separators is proposed, where Co/CoN₄ layer serves as adsorption-catalytic centers for high-order and low-order LiPSs, combined with 2D MXene layer that acts as the second barrier for additional leaked LiPSs, and thus a circulation interface of adsorption-conversion-reactivation of S species has been realized, effectively alleviating the shuttle effect in lithium-sulfur/selenium batteries.

How to achieve rapid and accurate detection of serotonin in organisms is a key question in studying the pathogenesis of psychiatric disorders such as depression. To study the action mechanism of serotonin, we have developed a highly selective molecular probe based on thiol-ene click cascade nucleophilic reactions that enables real-time imaging of brain tissues in depression.

Tensile-strained copper hollow-fiber penetration electrode (Cu HPE) enhances the asymmetric C−C coupling to steer the selectivity and activity of multicarbon (C₂₊) products. A faradaic efficiency of 84.5 % and a partial current density as high as 3.1 A cm⁻² for C₂₊ products, alongside a single-pass carbon efficiency of 81.5 % and stable electrolysis for 240 h were demonstrated in a strong acidic electrolyte (pH=1).

Three paramagnetic one-dimensional assembles were successfully obtained from spherical polyoxometalates and multinuclear platinum complexes. Each assemble has mixed-valent metal oxidation states and unpaired electrons on metal d orbitals, showing semiconducting behaviours, which was 10⁵ times greater than that of the parent polyoxometalates.

By integrating photochemistry within kinetic target-guided synthesis (KTGS) techniques, we significantly accelerated the identification of enzyme inhibitors, demonstrating the potential of KTGS for rapid discovery of bioactive ligands in medicinal chemistry. The chiral linkage gives rise to the formation of enantiomers, which were assessed via a highly stereocontrolled synthesis of both templated ligand enantiomers.

Ultrathin layered solid electrolyte interface (SEI) is in situ constructed by dual reaction strategy, which synergistically utilizes spontaneous electrostatic reaction and electrochemical decomposition via introducing the functional additive CMIM (1-carboxymethyl-3-methylimidazolium chloride). CMIM′s unique molecular structure also enables the disruption of hydrogen bonding, guides uniform Zn²⁺ deposition, and promotes rapid ion transfer to enhance battery stability, thus affording highly reversible queous zinc-ion batteries.

A novel 1,2,5-trifunctionalization of unactivated alkenes is established by merging dipolar cycloaddition with photoredox promoted radical ring-opening remote C(sp³)−H functionalization. This transformation was triggered by XAT followed by a cascade of 1,5-HAT and intermolecular fluorine atom transfer. With this method, a broad spectrum of valuable β-hydroxyl-ϵ-fluoro-nitrile products are synthesized from readily available terminal alkenes.

This work offers a concept for enhancing the electrochemical activation and dehydrogenation of lattice-hydroxyl-groups (M²⁺−O−H⇌M³⁺−O) to produce high-valence Ni³⁺/Co³⁺ active sites for 5-hydroxymethylfurfural oxidation reaction. Notably, the dehydrogenation process is significantly augmented due to the electron-deficient Ni/Co sites and weakened O−H bond strength derived from the robust electron-withdrawing capability of benzoic acid ligands.

Femtosecond infrared spectroscopy is used to study the out-of-equilibrium dynamics of the ultrafast and persistent photoinduced phase transition of the Rb_0.94Mn_0.94Co_0.06[Fe(CN)₆]_0.98 ⋅ 0.2H₂O material, induced at room temperature. The data show that optical excitation creates small CT polarons within 250 fs. Above threshold excitation, a cooperative and macroscopic phase transition occurs on the 100 ps timescale.

The direct amidation of esters is converted from a ball-milled process into a continuous solvent-minimised reactive extrusion protocol capable of delivering 500 grams (1.3 mols) of amide product over a continuous operation for 7 hours. Key to this, was translation of heating profiles used for the ball-milling study directly to the extruder and consideration of the physical form of input substrates.

Selenium is introduced into the halide perovskite framework, for the first time, using the zwitterionic selenocysteamine. The average and local structures of these mixed-anion perovskites help determine the band structures and potential trap states, respectively. Calculations show dispersive bands and direct gaps, which can be further tuned to straddle the ideal values for tandem solar cells using halide alloying and chalcogenide alloying.

To investigate lysine methylation comprehensively, a robust method for Kme1 enrichment was established. Dimethoxyaryl diazonium crosslinked Kme1 with high reactivity and selectivity among tryptic peptides from cell samples. As a result, over 10000 Kme1 sites were identified by proteomic analysis. Furthermore, we found a significant amount of methyl marks that were not S-adenosyl methionine-dependent by isotope labeling experiments.

We report an oxygen independent photoactivatable chemotherapeutic, Ru-TAP-PDC3, that targets mitochondrial guanine quadruplexes. Photoirradiation induces depletion of mitochondrial DNA and mitochondrial dysfunction causing cell death by triggering apoptosis. Importantly, Ru-TAP-PDC3 is negligibly toxic under dark conditions but upon irradiation, significant toxicity is observed.

Structural biomaterials such as spider silk and mussel byssi are fabricated by the chemoresponsive phase separation of biomacromolecules. Inspired by these biofabrication schemes, this work demonstrates that ion-specific interactions between cationic polyelectrolytes and ionic cosolutes offers new opportunities to control the assembly, structure, and dynamic physical properties of soft matter.

A nonflammable binary DEE electrolyte comprising of LiTFSI and solid BdS is reported, which demonstrates enhanced Li metal compatibility while exhibiting high Li⁺ ion migration number, ionic conductivity, and wide electrochemical window for Li metal battery applications.

We report on the synthesis, characterization and reactivity of adducts of tris(pentafluoroethyl)gallium and -indium, M(C₂F₅)₃ (M=Ga, In) with weak donor molecules, particularly of the first structurally characterized thionyl chloride adduct of a main group element Lewis acid. [Ga(C₂F₅)₃(SOCl₂)] is accessible by dehydration of [Ga(C₂F₅)₃(OH₂)₂] with thionyl chloride.

This study presents the first red-light triggered H-abstraction photoinitiators for hypoxic cancer photodynamic therapy. The photoinitiator can initiate red-light-induced H-abstraction with intracellular biomolecules to induce necroptosis and ferroptosis. Moreover, photoinitiator was degraded following H-abstraction, avoiding the long-term phototoxicity. This study provides a crucial molecular strategy for hypoxic tumor therapy.

A series of fully conjugated sp²-c covalent organic framework integrated with multipolar structures and enrichment sites have been prepared for overall photosynthesis of H₂O₂. Benefiting from optimal multipolar structures and functional sites, TACOF-1-COOH facilitated charge transfer and mass movement during the photocatalysis process, leading to highly efficient ORR performance with a H₂O₂ production rate of 3542 μmol g⁻¹ h⁻¹.

Te−Bi NRs were synthesized through in situ reconstruction of Bi₂Te₄O₁₁ NRs under the CO₂RR condition. The obtained Te−Bi NRs exhibit remarkably high performance in CO₂RR towards formate with high activity, selectivity, and stability across all pH conditions (acidic, neutral, and alkaline).

Hydrogen bonding 2D/2D Z-scheme junction BiOBr@NiFe-LDH with stable interface and abundant atomic-level charge transfer channels is fabricated. Bi⁰ and Ni⁰ in situ formed at the interface and surface of LDH separately act as electron mediator and electron extractor to facilitate the charge migration. The system exhibits a high charge transfer efficiency up to 71.2 %, nearly 10-fold than the BiOBr, optimizing the efficiency of photocatalytic activation of PMS for tetracycline degradation.

A red light-activated nanocatalyst MB@PMOF has been developed to facilitate in situ synthesis of antimicrobials through a photoredox-catalytic click reaction in bacterial infected tissue. This approach enables precise and potent treatment against severe bacterial infections, providing innovative design concepts for a new generation of alternative antibacterial therapies.

An efficient method for para selective C−H borylation of aromatic aldimines and benzylamines has been developed using iridium catalysis. While aromatic aldimines participate in a sterically controlled Lewis acid−base interaction where the in situ generated pinacolborane acts as a transient directing group (DG), interestingly the origin of the para selectivity of benzylamines stems from the sterical demand of the N-substituents.

3D flower-like SnS₂ composite with abundant sulfur vacancies is synthesized under the regulation of functionalized carbon dots, and it is employed as filler to optimize the microenvironment in solid polymer electrolytes. As a result, the constructed composite electrolyte not only exhibits high room temperature ionic conductivity and Li⁺ transference number but also demonstrates significantly improved mechanical properties, providing solid state lithium metal batteries with excellent cycling stability and extended cycle life.

Discover a novel additive-free strategy to create LiF-rich cathode-electrolyte interphase (CEI) through low-temperature formation cycling. Achieving superior battery performance across a wide temperature range, this approach is applicable to various cathode systems, highlighting its versatility and potential for advancing battery technology.

A hetero-superlattice Zn/ZnLi anode containing periodic arrangements of metallic Zn phase and zincophilic ZnLi phase at the nanoscale, is well designed and fabricated via electrochemical lithiation method. The HS−Zn/ZnLi anode can effectively guide Zn ion stripping/deposition evenly during repeatedly stripping/plating processes. Consequently, the HS−Zn/ZnLi anode with hetero-superlattice structure can cycle over 2800 h without a short-circuit at 2 mA cm⁻².

A new strategy for enantiodivergent accessing P(V)-stereogenic molecules via palladium/norbornene cooperative catalysis was established. The enantioselectivity of this protocol was tuned by the polarity of the solvent, thus providing both enantiomers of the P(V)-stereogenic molecules using a single chiral norbornene catalyst.

A multi-component covalent triazine framework denoted as 4C-TA_0.5TF_0.5-CTF) with fine-tuned donor-donor-π-acceptor interaction is demonstrated to establish a rapid lithium-ion transport channel and induce uniform Li deposition.

We found that deactivation of the PtZn/γ-Al₂O₃ catalyst occurred due to reconstruction from PtZn IMA to Pt₃Zn IMA. This deactivation mechanism differs from traditional coke deposition and sintering, as it is driven by the metal support interaction (MSI). Further investigation revealed that surface modification of alumina, such as with K ions, effectively inhibits the reconstruction of PtZn IMA, thereby enhancing the stability of propane dehydrogenation.

2-Alkenylarylimines have been shown to undergo 6π-azaelectrocyclization thermally to generate azabicyclic o-quinodimethanes. These o-quinodimethanes show dual nature as a cyclic diene and a benzylic diradical. The interception of the diradicaloid o-quinodimethanes by H-atom transfer enabled the synthesis of five tetrahydroisoquinoline alkaloids. The cyclic dienes were intercepted by [4+2] cycloaddition to generate bridgehead azabicycles.

A bottom-up synthesis strategy was used to introduce pore defects into the fully conjugated π-extended helicene. This modification transformed the helicene with original aggregation-caused quenching (ACQ) characteristics into a series of novel helicenes with dual-state emission (DSE) and circularly polarized luminescence (CPL) properties. Consequently, the application range of the helicene in chiral luminescent materials was expanded.

Polycyclic aromatic hydrocarbons (PAHs) with split azulene embedment remain experimentally rare, despite their exceptional properties. Herein, Pery-57 with split azulene is synthesized and exhibits remarkable characteristics like NIR II absorption, p-type transport, and outstanding redox features like diradical character, global antiaromaticity, hydrogen capture. This work stimulates new interest in azulene-like nonalternant PAHs.

The stability of the subnanometer PtIn clusters confined in the sinusoidal 10MR channels of MFI zeolite can be greatly enhanced by the presence of framework In(III) species, resulting into a high activity and stability during the ethane dehydrogenation reaction for more than 1000 h at 650 °C.

A MOF-on-MOF heterostructured electrocatalyst with interfacial dual active sites and build-in electric field is constructed for nitrite reduction reaction, delivering an NH₃ yield of 11.46 mg h⁻¹ cm⁻² and a Faradaic efficiency of 98.4 %.

A novel green solvent, γ-valerolactone (GVL), efficiently facilitates the photocatalytic activation of C−H bonds in benzylic compounds. Mechanistic studies reveal that GVL′s high dielectric constant (ϵ) increases the driving force (−ΔG), and its large refractive index (n) reduces reorganization energy (λ), collectively reducing the reaction barrier (ΔG^≠). This research advances the overlooked solvent effects in semiconductor photocatalysis.

Metal halide perovskites (MHPs) photocatalysts are bi-functionalized with lead sulfide (PbS) and amorphous molybdenum sulfide (MoS_x) co-catalysts on the surface. PbS can passivates the defects of MHPs and MoS_x provides active sites for hydrogen evolution reaction (HER), thus synergistically enhancing the charge transport efficiency and HER catalysis and achieving a superior solar-to-chemical (STC) energy conversion efficiency of 4.63 %.

An N-Methylmethanesulfonamide (NMS) additive is introduced to alter the primary solvent shell of Zn²⁺, chemically adsorb on the metallic Zn surface, and in situ form an N-rich organic and inorganic (ZnS and ZnCO₃) hybrid SEI. These effects suppress the water-induced side reactions and ensure the fast transport kinetic and uniform Zn deposition.

Exciton binding energy (E_b) is recognized as a key physical parameter for efficient charge-carrier generation in opto-electronic devices and organic photocatalysts (OPCs). The correlation between E_b and aggregation is important to achieve a small level of E_b in the solid state. Here, the influence of aggregation behavior on E_b and device/OPC functions were revealed by using two organic semiconductors with different aggregation behaviors.

2-Bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-on (RRx-001) wurde als potentieller Radiosensitizer vorgeschlagen. In dieser Studie untersuchten wir den Zerfall des Moleküls bei Elektronenanlagerung. Die Hauptdissoziationswege des Anions beinhalten eine Freisetzung des Bromatoms oder der NO₂ Gruppe, die um das eingefangene Elektron konkurrieren. Die beobachteten schnellen Reaktionsvorgänge bieten einen alternativen Weg zur Sauerstoffanreicherung von sauerstoffarmen Tumoren an.

Ammoniak ist ein vielversprechender Wasserstoffträger. Die Ammoniak-Oxidationsreaktion (AmOR) wurde durch direkte Nutzung von gasförmigem NH₃ an Gasdiffusionselektroden untersucht. Die selektivste Katalysatorzusammensetzung der verschiedenen Multimetallkatalysatoren war in der Lage, NH₃ hauptsächlich zu NO₂⁻ zu oxidieren und dabei die Bildung von energetisch günstigem N₂ sowie O₂ weitgehend zu vermeiden, während an der Kathode ausschließlich H₂ gebildet wurde.

Die direkte Editierung des heterozyklischen Gerüsts pharmazeutischer Leitstrukturen erfordert in der Regel überstöchiometrische Mengen kostspieliger hypervalenter Iod(III)-Reagenzien. Wir berichten hier über die elektrochemische Stickstoffinsertion in Indole, die durch die Sauerstoff-Reduktionsreaktion (ORR) ermöglicht wird. Dies führt zur Bildung von biologisch aktiven Chinazolinen.

Wir berichten über die Synthese hoch elektrophiler fluorierter Dialkylchloroniumsalze [Cl(CH₂CF₃)₂][M(OTeF₅)_n] (M=Sb, n=6; M=Al, n=4), die in der Lage sind, schwache Nucleophile zu alkylieren, während ihre hohe Affinität zu Hydridionen die Aktivierung linearer Alkane ermöglicht, was zur Bildung verzweigter Carbokationen führt.

The bismuth cation [BiMe₂(SbF₆)] reacts with [Pt(PCy₃)₂] to give heterobimetallic [(PCy₃)₂Pt→BiMe₂(SbF₆)] (1). Compound 1 and related species show the first unsupported M→Bi donor–acceptor interactions (M=transition metal), establishing [BiMe₂]⁺ as an effective and robust Z-type ligand, and experience pronounced spin-orbit coupling. 1 activates H₂, triggering a sequence of reactions that furnish the umpolung of Pt→Bi to Bi→Pt dative bonding.

A stable π-extended nanographene radical (NR1) is synthesized and isolated in the crystalline form. NR1 exhibits a distinctive four-stage amphoteric redox behavior, demonstrating that π-extension could serve as a viable approach to unlock the multistage redox ability of delocalized organic radicals.

Introduction of proton relays close to the catalytic metal center boosts hydrogen photosynthesis with cobalt(II) TPMA complexes leading to a 4-fold increase in quantum efficiency and up to a 22-fold gain in turnover number.

UV/Vis spectroscopy is coupled with a packed bed flow reactor to extract quantitative kinetic data, simultaneously monitoring both the catalyst redox state and the gas-phase dynamics during the Selective Catalytic Reduction of NO_x with NH₃ over Cu-CHA. This work highlights the accessibility of kinetic studies directly from operando UV/Vis spectroscopy paving the way for elucidating the structure–activity relation under kinetically relevant conditions.

Polyoxometalates (POMs) can serve as an effective stabilizing ligand for metal nanoclusters to impart distinctive structures and properties. We report the synthesis of a surface-exposed Au−Ag alloy nanocluster within a ring-shaped POM through reaction of an Ag nanocluster with Au ions (Au⁺). The resulting Au−Ag alloy nanocluster demonstrated remarkably enhanced visible-light-responsive photocatalytic activity in the aerobic oxidation reactions and stability compared to the parent Ag nanocluster.

An electroenzyme-coupled system has been constructed for continuous biosynthesis of valuable chemicals with high production rates and turnover frequencies. In the system, formate is obtained from electroreduction of CO₂ with good faradic efficiency at high current density and utilized for NADH regeneration with high selectivity. As a temporary energy carrier, formate ensures efficient energy transfer from electricity to chemical production.

With customized designs of the deposition layer on the BiVO₄ photoanode, two PEC systems were developed for highly efficient catalytic C−N and C−P bond formation. The modified BiVO₄@Al₂O₃ demonstrated substantial performances for important yet challenging coupling between amides and xanthenes under aerobic conditions, whereas BiVO₄@Ni₁Co₇Pi manifested its versatility in C−P coupling between aryl bromides and diphenylphosphine oxide, facilitated by a Ni-catalyzed cycle under ultralow potentials.

A sterically demanding, electrophilic [2.2]isoindolinophanyl-based carbene (iPC) acts as a potent π-chromophore and participates in metal-to-ligand charge-transfer (CT) transitions in [RhCl(CO)₂(iPC)] and intra-ligand-“through-space”-CT transitions in [Au(iPC)₂]OTf (5). The steric demand of the iPC leads to ultralong-lived green phosphorescence (τ=185 μs) of 5 in solution, which in combination with the large accessible π surface area has been exploited for energy transfer (EnT) photocatalysis.

An oxidative ring contraction strategy was employed to accomplish the first total synthesis of baphicacanthcusine A. Rapid construction of a key seven-membered-ring intermediate set the stage for a series of diastereoselective oxidations to access the skeleton of the natural product. Selective C−H oxidation gave rise to baphicacanthcusine A in 11 steps from 3,3’-biindole.

Fluorescent probe for discovering the critical roles of CYP2D6 in natural systems: A fluorescent probe for CYP2D6 is designed using a tailored molecular strategy. The probe quantitatively detects and images CYP2D6 activity in various living systems, thereby providing a robust tool for exploration of the biological functions of CYP2D6 in the pathogenesis of diseases and detailed investigation of CYP2D6-induced MBI.

Chiral 1T−MoS₂ nanosheets were produced via hydrothermal synthesis in the presence of tartaric acid as a chiral ligand to control mirror symmetry breaking. This novel chiral inorganic nanomaterial exhibits a chiral morphology as well as remarkably high chiroptical activity, with a g-factor of up to 0.01. The optimization of the synthetic conditions and the material's formation mechanism revealed critical details on the transfer of chirality.

Be positive! A novel Ni superoxide dismutase mimic was engineered, taking advantage of the versatility of the Amino Terminal Cu^II- and Ni^II-binding (ATCUN) motif to introduce positive charges around the Ni^II center. This strategy yielded the most potent synthetic NiSOD mimic reported to date, in terms of catalytic efficacy and stability.

Polymerized N-heterocyclic carbenes (NHC) are used to covalently immobilize Au and Ag atoms to yield bimetallic random copolymers. Reduction of such polymers results in the formation of polyNHC-capped alloy and core–shell AuAg bimetallic nanoparticles whose structures are governed by the relative metal content in their corresponding metallopolymers. The application of these nanomaterials in electrocatalytic oxygen reduction reaction is demonstrated.

A schematic of monoethylene glycol (MEG) adsorption measurements using a permeable membrane and a Type 3 porous liquid showing selective adsorption due to inclusion into the pores of the dispersed porous solid.

A general and selective alkylation method without using strong acids, bases, or metals is reported. This method, which is mechanistically related to the Arbuzov-Michalis reaction, employes a combination of phosphinites/phosphites and ethyl acrylate as effective alkylating agents, achieving chemo- and site-selective modification of complex natural products and pharmaceutical agents.

A highly efficient biocatalytic route for the atroposelective synthesis of biaryls by dynamic kinetic resolution (DKR) was developed. This DKR approach features a transient aza-acetal bridge-promoted racemization followed by an engineered imine reductase (IRED)-catalyzed stereoselective reduction to generate the axial chirality, providing various biaryls in high yield with excellent enantioselectivity (up to >99 : 1 er).

A novel dehydration-assisted functionalization (DAF) enables rapid ligand exchange and dense surface modification of quantum dots (QDs) and quantum rods (QRs). This study highlights DAF's role in preparing chiral QRs, engineering QD surface charge, utilizing QR aggregates, and conjugating DNA onto cadmium-free InP/ZnS QDs. DAF provides a versatile solution for diverse QD and QR functionalization applications.

Sulfurized two-dimensional metal–organic framework (2D-MOF) promises high capacity Mg²⁺ storage. On the one hand, the 2D nature of the material enables fast and reversible Mg²⁺ diffusion. On the other hand, the S functional groups serve as reversible redox centers to host Mg²⁺.

Dilithiumtetraalkinylpalladate, die in situ aus Palladiumsalzen und Lithiumalkinylen gebildet werden, fördern effektiv die Kopplung von nicht aktivierten Arylchloriden mit verschiedenen Nukleophilen unter Bildung von C−C- oder C−N-Bindungen. Die Anwendbarkeit des Protokolls wurde durch die Synthese von 49 Molekülen, einschließlich pharmazeutisch relevanter Verbindungen, nachgewiesen. Die Lithiumalkinyle wirken als sehr elektronenreiche Liganden, die unter den basischen Reaktionsbedingungen weitgehend inert zu sein scheinen.