This minireview provides a summary of the chemistry and mechanisms governing reactive species (RXS) based nanomedicine, focusing on metabolic regulation, the role of nanomedicine in RXS generation and elimination. The challenges and future prospects associated with RXS for disease treatments are further discussed, aiming to facilitate the clinical translation of RXS-based nanomedicine and open new avenues for improved therapeutic interventions.

In contrast to DC electrolysis, alternating current (AC) features polarity reversal and periodic variation, and will provide more chances and potentials for organic synthesis. This minireview delineates the unfolding landscape of recent progress in AC-driven organic transformations and endeavors to dissect disparities between DC and AC electrolytic patterns from their physical principles, reaction features and selectivity control.

Antimicrobial resistance is one of the most serious threats to public health but the problem is compounded by the lack of new drugs with new modes of action in the development pipeline. In this review, we spotlight four emerging antibacterial strategies that take advantages of the unique chemical properties of transition metal complexes, namely Trojan horse, triggered warhead release, “new-to-nature” chemistry, and biomimetic reactions. We further propose that transition metal complexes can replenish this diminishing stockpile of drug candidates by providing compounds with unique properties that are not easily accessible using pure organic scaffolds.

Polyimides have proven to be highly versatile in nearly all areas of rechargeable battery applications, spanning from active electrode materials to separator coatings. This review presents a summary of significant research conducted over the past 15 years, showcasing their potential to pave the way for a new era of effective utilization of these polymers in next-generation batteries.

Photochemical deracemization offers a unique opportunity to directly obtain enantiopure compounds from their racemates. Short-lived intermediates play a key role in the enantioselectivity-determining step. The review covers comprehensively the research performed in the area and discusses current developments.

An s-block Potassium single-atom catalyst (SAC) with a K-N₄ configuration was prepared and used as a highly efficient oxygen reduction reaction (ORR) electrocatalyst. The excellent ORR activity is attributed to K/C atoms acting as dual adsorption sites, which can synergistically optimize the free energy of oxygen-containing intermediates and tune the rate-determining step.

By integrating multivalent nucleic acid aptamers and DNAzyme sequences into long single-stranded DNA and further forming metal-DNA nanocomplexes using rolling circle amplification (RCA) technology, researchers have successfully established a DNA drug delivery platform that combined chemo-dynamic therapy (CDT) and autophagy inhibition therapies. The platform overcame the shortcomings of short-stranded DNA, such as poor stability under physiological conditions, short blood circulation time, and easy clearance by the organism.

The mechanisms of photoinduced charge transport and electron dynamics in conductive 2D metal–organic frameworks (MOFs) and their correlation with photoconductivity are investigated using multiple spectroscopy techniques. A through-space hole transport mechanism through the interlayer sheet π–π interaction is identified, where the photoinduced hole state resides in the HHTP ligand and the electronic state is localized at the metal center.

The E3 ligase CHIP promotes ubiquitination of preformed Tau filaments in vitro and in living cellular models. The structural conformations of the fibrils restrict ubiquitination to specific regions of Tau. Tau seeding activity is not impaired by ubiquitination.

The novel dual-network design strategy is proposed to prepare a high-performance cellulosic composite bioplastic metafilm with exceptional mechanical toughness (23.5 MJ m⁻³), flame retardance, and solvent resistance. Moreover, it has a high maximum usage temperature (245 °C), lower thermal expansion coefficient (15.19 ppm °C⁻¹), good biocompatibility, and natural biodegradation, which is competitive for plastic substitute.

Zn and Co based POP with different Lewis acidity has been developed for controlling water splitting and CO₂ reduction under sunlight. Low-cost option of syngas production with adjustable H₂/CO ratio was demonstrated obtained by skipping the use of any sacrificial electron donors (SEDs), cocatalysts, or photo-sensitizers.

A single-crystalline ortho-alkoxy-benzamide directed hydrogen-bonded crosslinked organic framework (H_COF-50) has been synthesized for BF₃ adsorption and demonstrates a record-high capacity of 14.2 mmol/g. The formed H_COF-50 ⋅ BF₃ complex showed controlled BF₃-releasing for more controlled cationic vinyl ether polymerization.

Combining photocatalysis and biocatalysis allows for the repurposing of the ‘ene’-reductase enzyme GluER to achieve the enantioselective synthesis of benzo-fused heterocycles, and various benzoxepinones, chromanone and indanone were specifically afforded in high yields with good to excellent enantioselectivities after protein engineering of GluER.

The first metal–organic frameworks with formally Cu(I)/Cu(III) mixed valency are reported. These bench stable Cu(III)-containing frameworks coordinated by a non-innocent ligand are characterized and investigated for multielectron redox properties, unveiling the redox-active sites at both the copper and organic ligand. This is also the first time that formally Cu(III) species are witnessed in metal–organic extended solids.

Different effects have been shown to control the formation of [2]catenanes with different bridges between pyridine donors. The formation of [2-IL](OTf)₄ is aided by solvophobic effects and [3-IL](OTf)₄ is stabilized by solvophobic effects and π⋅⋅⋅π stacking. The π⋅⋅⋅π stacking between the pyrene groups is essential for the formation of [4-IL](PF₆)₄ and [5-IL](PF₆)₄, where the enhanced stability of [5-IL](PF₆)₄ is based on the more stable Au−C_NHC bonds.

The cationic organo-tantalum catalyst AlS/TaNp₃ (94 %) and AlS/TaNp₂_AlNp (6 %) was synthesized via Np₃Ta=CH^tBu chemisorption on Brønsted acidic sulfated alumina (AlS). The proposed structures are in good agreement with SSNMR, DRIFTS, XANES, EXAFS, and DFT computation. Highly efficient AlS/Ta-mediated hydrogenolysis of diverse pre- and post-consumer polyolefin plastics to lighter alkanes is achieved.

Four novel cinnamoylphloroglucinol dimers were discovered from C. operculatus. Biomimetic syntheses of these and two known dimers were developed through a strategy in which the activation of stable biogenetic building blocks was a crucial step and key features included a unique cascade reaction and a rare inverse-electron-demand Diels–Alder reaction. One of the dimers showed activity against herpes simplex virus type 1 through a new mode of action.

A 980/808 nm NIR programmed in vivo miRNA magnifier is developed by conjugating an activatable DNAzyme walker set to rare-earth nanoparticles, which detects tumors earlier than size-monitoring techniques. The 980-nm excitation-activated DNA nanomachine for miRNA-21 recognition and signal amplification to suppress “false positive” signals, and imaging in the NIR-II region under 808 nm excitation provided deeper penetration and lower background.

Nanosheet-assembled Zr-porphyrin hexagonal prisms exhibit broadband photon harvesting and excellent photocatalytic ability, enabling controlled photosynthesis of ultrahigh molecular weight (M_n>1,500,000) polymers with low dispersity (Đ≈1.5) in an initiator-free, oxygen-tolerant reversible-deactivation radical polymerization system regulated by full-range visible light and natural sunlight.

Amine ligands have been widely used to tailor surface properties of colloidal nanocrystals (NCs) for facilitating their synthesis, performances and processing, but detailed understanding of their interaction has remained a challenge. Here, a strategy based on detecting ¹¹³Cd, ⁷⁷Se and ¹⁵N NMR signatures augmented with DFT modeling was developed. It enables to identify distinct surface sites and the corresponding ligation of amines in CdSe NCs.

The performance of eco-friendly PEA₂SnI₄ perovskite light-emitting diodes (PeLEDs) lags far behind that of lead-based PeLEDs. We demonstrated a ligand engineering strategy that uses GSH as a surface ligand to strongly interact with I⁻ and Sn²⁺ in perovskites, which thus reduces the film crystallization rate and suppresses the oxidation of Sn²⁺ ions. Pure red PeLEDs based on the modified PEA₂SnI₄ achieve a record EQE_max of 9.32 %.

Three-component multiblock 1D supramolecular copolymers with up to 9 blocks have been successfully synthesized by precise control of the pathway complexity of Ir(III) complexes. The segmented structures of the multiblock copolymers could be characterized by both TEM and SEM. These three-component block copolymers with tunable block sequences will advance the development of functional block copolymers.

An easily solution-processed parallel planar heterojunction (PPHJ) strategy boosts the efficiency of Sb₂S₃ solar cells up to 8.32 %, by integrating the distinctive structures of Sb₂S₃ layer and the duplexity of CH₃NH₃PbI₃ layer in charge transportation. The PPHJ device consists of the conventional planar heterojunction (PHJ) subcells in a parallel connection, but eliminates the normal complexity in both tandem and parallel tandem PHJ systems.

In this contribution, the synthesis, structure, and reactivity of metal (uranium) diazomethanediide complexes containing bridging and/or terminal isocyanoimido groups (U=NNC) are presented. By a combined experimental and computational study, unique reactivity patterns were identified and this gained knowledge provides the first insights into the reactivity of complexes containing a metal isocyanoimido (M=NNC) fragment.

An electrochemical selenoetherification (e-SE) methodology that enables efficient and selective functionalization of polypeptides is described. e-SE employs mild reaction conditions to facilitate the formation of stable selenoether-linked conjugates through contraction of diselenide bonds. Compatibility with diverse functionalities and complex cargoes is demonstrated through assembly of valuable bioactive polypeptide conjugates.

The chemical modification at precise sites within biomolecules is essential to assist in understanding their function. The incorporation of bio-orthogonal reactive groups provides a strategy for selective tagging, however cross-reactivity is problematic when dual modification is required. Glutathione (GSH) is used to control the reactivity of ynamine and cyclooctyne reagents in sequential (3+2) cycloaddition reactions.

Nickel doping introduces spin-polarized electrons and weakens H−S bonds, resulting in enhanced H₂ production. Moreover, the interfacial Ni−O bond significantly strengthens the built-in electric field (E) and reduces the energy barrier. Benefiting from doping and S-scheme heterojunction engineering, TiO₂/Ni_0.08-Zn_0.2Cd_0.8S quantum dots (QDs) show good charge transfer and separation, leading to improved H₂ production and benzylamine oxidation.

Stepwise metalation of a polynucleating ligand generated heterobimetallic clusters featuring two redox inactive Lewis acids (Zn²⁺) and one transition metal (Ni). Reduction of the [Zn₂Ni] cluster and reaction with a nitrene transfer reagent yielded [K(THF)₃][(^F,tbsL)Zn₂Ni(μ³-NAd)]. Ni K-edge XAS (X-ray absorption spectroscopy) studies support the assignment of the primary redox pair as a divalent nickel coupled to an imidyl ligand.

The 1,2-diethoxyethane (DEE) molecule promotes the moderate Na⁺-DEE coordination, thus leading to the uniform and inorganic-rich solid electrolyte interphase, as proved by the cryogenic electron microscopy characterizations. Consequently, the Na metal anode is highly stable in the NaPF₆/DEE-based electrolyte with a high Coulombic efficiency of 99.9 % and dendrite-free deposition behavior.

A self-standing COF membrane was prepared for ultrafast proton conduction in flow battery. The −SO₃H groups in macromolecule chains offer sites to interact with the precursors of COF and function as long-range ordering growing template to enhance the crystallinity of self-standing COF membrane. Well-defined channels of COF membranes promised high proton conductivity and excellent battery performance.

We developed a strategy called glycan MEtabolic Fluorine LAbeling (glycan MEFLA) for selectively tagging glycans of tumor cells. It allows for efficient and selective labeling of tumor cells by fluorinated monosaccharide-based probes (Ac₄ManNTfe and Ac₄GalNTfa), enabling in vivo visualization of tumor cells and in situ assessment of glycosylation changes via ¹⁹F MRI with high sensitivity and deep penetration.

A Ni−Fe dual-single-atom catalyst (DSAC) with adjacent Ni−N₄ and Fe−N₄ pair sites was developed for concentrating solar-driven photothermal CO₂ reduction. This work demonstrated that constructing an appropriate distance between Ni and Fe atoms via an N-bridged Ni−N−N−Fe configuration was conducive to the main *COOH and *HCO₃ dissociation processes for solar-driven photothermal CO₂ reduction.

A gene-editable palladium-based bioorthogonal nanoplatform was developed to improve tumor management, which can polarize macrophages to the anti-tumoral M1 phenotype, reprogram tumor cells to suppress anti-phagocytic signals, and induce the activation of sequestered prodrugs through bioorthogonal catalysis, thereby facilitating macrophage phagocytosis and allowing for more effective tumor treatment.

A novel core–shell reactor partitioning CYP450 and prodrug by ZIF-8 is proposed to improve the efficacy, selectivity, and safety of enzyme-prodrug therapy. Here, cytochrome P450 (CYP450) is immobilized in ZIF-8, and the antitumor drug dacarbazine (DTIC) is coordinated and deposited in its outer layer, leading to a high drug loading capacity of 43.6±0.8 %. This reactor exhibits NADPH-sensitive in situ prodrug activation specificity in tumor cells, which achieves high prodrug conversion efficiency of 36.5±1.5 %.

A polymerizable organic molecule monomer, N-carbamoyl-2-propan-2-ylpent-4-enamide (Apronal), is introduced into the perovskite precursor to form a polymer (P-Apronal) through thermal crosslinking, which can effectively interact with shallow defects, leading to enhance crystallinity and reduced lattice strain, especially inhibiting the migration of I⁻, thus resulting in enhanced long-term stability and performance of devices.

A synthetic approach has been developed to introduce multiple main group heteroatoms at the zigzag edge of the anthracene framework. BN annulation has led to a naphthalene derivative with an NBO bond. A subsequent BO annulation has been used to extend the fused aromatic ring to afford an anthracene derivative featuring an NBOB system. Changing the NBOB to an NBNB system has further increased the chemical diversity.

Configurational entropy (compositional disorder in the anion sublattice) shows a direct correlation with ionic conductivity in lithium argyrodite superionic solid electrolytes.

A fully non-fused ring acceptor, GS60, is synthesized to improve photostability and reduce material costs in Organic Solar Cells. By blending with non-fused ring polymer, PTVT−T, the obtained active layers possess favorable morphology and suppressive charge recombination. Encouragingly, manufactured large-area organic photovoltaic modules exhibit outstanding photostability and power conversion efficiency under various light conditions.

Inspired by pressure cooker principles, we employ high-pressure methods to address challenges in processing high molecular weight polymers. Successfully dissolving HW-D18 in chloroform at 100 °C within pressure vials, heightened vapor pressure elevates boiling point and solubility of chloroform. This enables the creation of blend films with superior properties, ultimately achieving an excellent PCE of 19.65 %, setting a new record for binary OSCs.

A hierarchical porous hyper-crosslinked organometallic polymer containing Ir-abnormal NHC-based single-site molecular catalyst centers was designed and developed for CO₂ hydrogenation-to-formate salt production in water that delivered an extremely high single-run TON of 50816, and excellent reusability with a cumulative TON of 285400 in 10 cycles with just 1.6 % activity loss/cycle.

A highly efficient and stereospecific cross-coupling of propargylic mesylates and Grignard reagents for the synthesis of diverse chiral allenes catalyzed by a recyclable heterogeneous nanocopper catalyst is reported. The synthetic utility of this sustainable methodology was further demonstrated by its application to the asymmetric total synthesis of 5 valuable allenic natural products.

Moving from homoleptic triple helical erbium complexes to heteroleptic adducts boosts the quantum yield of near-infrared to visible molecular-based light-upconversion by three orders of magnitude in solution at room temperature.

The binding of N-heterocyclic olefins to a silicon surface is investigated revealing an adsorption in the ylide form drastically depending on the N-substituents. Large N-substituents lead to upright molecules and ordered monolayers while for small N-substituents a flat-lying geometry is favored. The geometry is found to have a strong influence on the properties of the films, e.g. their work function.

Two formamidinium (FA)-based semiconductor spacers, namely TTFA and BTFA, respectively, were successfully developed for two-dimensional (2D) Ruddlesden-Popper perovskite solar cells. The nucleation and crystallization kinetics of 2D perovskite films were systematically investigated and understood using in situ optical microscopy and in situ grazing incidence wide-angle X-ray scattering measurements. The device based on (TTFA)₂MA_n−1PbnI_3n+1 (n=5) achieved a record efficiency of 19.41 %.

A reductive cross-electrophile coupling of allylic carbonates under Ni-catalysis provides access to unique 1,5-dienes featuring a quaternary stereogenic center under high chemo-, regio-, diastereo- and enantio-control. Mechanistic studies align well with a catalytic cycle based on a Ni(0)/Ni(II) couple with a crucial role for divalent Zn boosting the overall kinetics and selectivity while favoring a key bimetallic C−C bond formation.

We developed a facile in situ strategy to precisely control DNA aptamer valences on the surface of luminescent gold nanoparticles (AuNPs) with emission in the second near-infrared window and further demonstrated that not only the tumor-targeting efficiencies but also the subcellular transport of AuNPs show precise valence dependence.

The oxidation of closed-[7]helicenes with [bis(trifluoroacetoxy)iodo]benzene gave the corresponding dimers connected at the β-positions of the pyrrole units through a remarkably elongated C−C bond of about 1.60 Å. Homolytic bond dissociation took place upon UV irradiation to reform its monomeric form. The interconversion between monomeric and dimeric forms is associated with a turn-on of circularly polarized luminescence.

Supramolecular colloids based on polyoxometalates functionalized with boronic acids are modified with Pt particles to yield high-performance hydrogenation catalysts. Mechanistic studies reveal that the systems operate by a hydrogen spillover mechanism, enabling efficient hydrogenation of olefins to alkanes and nitroarenes to amines under mild conditions.

A single chiral emitter can induce the reversal of the cholesteric helix direction at a macroscopic level through a concentration-dependent effect at the molecular scale. This exceptional capacity endows the system with the extraordinary ability to seamlessly toggle the sign of circularly polarized luminescence, thus bestowing unparalleled mastery over the upconversion/downshift processes associated with the donor and acceptor moieties.

We report a label-free approach for imaging immune synapses of T cells by electrochemiluminescence microscopy, which allows us to discriminate specific T cell receptor (TCR)/peptide-loaded major histocompatibility complex (pMHC) recognition, as well as the role of auxiliary molecules (costimulatory and adhesion molecules). The results would be useful in the development of tumour vaccines and adoptive T cell transfer immunotherapy.

Photo-driven quasi-topological transformation exposing active nitrogen cation sites in a 1,10-phenanthroline-5,6-dione-based triazine-cored COF power continuous and stable charge separation/transfer, broaden visible-light adsorption, and provide strong Lewis acid sites for promoting O₂ adsorption. The optimal catalyst showed a high H₂O₂ yield rate of 11965 μmol g⁻¹ h⁻¹ under visible light irradiation.

Through in situ tannic acid (TA) molecule regulating the reconstruction of a Cu-based material, CO₂ reduction to C₂H₄ products with a Faraday efficiency (FE) of 63.6 % over 497.2 mA cm⁻² was achieved. The excellent performance can be attributed to TA induced adaptive Cu^δ+/Cu⁰ interface is beneficial to lower the energy barrier of C−C coupling, as well as the key COH intermediate stabilized through the hydrogen bond by the hydroxyl group in TA.

A practical electrochemical Ni-catalytic system has been developed for selective (hetero)arylation, alkenylation and alkynylation of cysteine-containing peptides. The high functional group compatibility and application to the synthesis of cyclic peptides either by cyclization or stapling demonstrate the potential protocol's utility in medicinal chemistry and chemical biology.

Upon doping bromine into zero-dimensional Cs₃Bi₂I₉ (space group P6₃/mmc), the crystal structure transforms into a two-dimensional layer structure as the bromine content reaches Cs₃Bi₂I₈Br. At this optimized composition the Cs₃Bi₂I₈Br single crystal has an outstanding detection performance in terms of record sensitivity for 100 keV hard X-rays, ultralow detection limit, and excellent imaging capability at 75 °C.

Aqueous electrolytes using Zn(BF₄)₂ as the salt and THF as the diluent are developed to improve the low-temperature performance of Zn-metal batteries. THF promotes the anion-cation aggregation and disrupts H-bond network, resulting in ZnF₂-rich solid-electrolyte interphase and facilitating the desolvation process at low temperatures.

A synergistic nitrogen binding site is constructed using adjacent open Cr(III) and F in a metal-organic framework (MOF). It gives benchmark N₂/O₂ selectivity and the highest high-purity oxygen productivity reported to date.

Cyclic azasilole derivatives undergo ring-opening with ¹⁸F^– anions under mild conditions and with high radiochemical yield. They represent a novel class of Silicon Fluoride Acceptor systems (CycloSiFA) and hold great potential for convenient kit-like labelling procedures in different medicinal applications.

The effect of the oxygen reduction reaction in accelerated stress tests using a Pt@HGS model catalyst on the catalyst degradation is investigated using RDE, IL-STEM grid and single entity electrochemical measurements. We demonstrate the importance of considering the modulation of the local pH when performing accelerated stress tests.

The promising anti-diabetic and anti-cancer drug V^IVO(acetylacetonato)₂ in the presence of lysozyme undergoes ligand exchange, partial or complete oxidation of V^IV to V^V to give two polyoxidovanadates (POVs): [V₄O₁₂]⁴⁻ and the unprecedented [V₂₀O₅₄(NO₃)]ⁿ⁻, based on the unusual [V₁₈O₄₆(NO₃)]ⁿ⁻ cage. They are stabilized by non-covalent or covalent interactions with the protein.

The de-novo rational design of short peptide motifs that assemble into fluorescent condensates with sequence-dependent phase behavior is investigated. Integrating experiments and molecular dynamics (MD) simulations, the role of sidechain solvation, n-π* interactions, and hydrogen bonding are highlighted through systematic sequence variations on an identical peptide backbone scaffold.

A dinuclear Zn complex showing anomalous visible-light absorption using Zn orbitals is developed. Key to the success of the low-energy absorption is the short distance between coordinatively unsaturated Zn centers, which enables the Zn−Zn orbital interactions to dramatically decrease the energy gap of the complex. Such Zn−Zn interactions facilitate untapped photo-functions of a group 12 Zn metal.

Enhancing CO₂ electroreduction in acidic media is reported via anchoring potassium ions near the Cu electrode decorated with an 18-Crown-6 molecule. This strategy could simultaneously favor *CO intermediate stabilization and protonation to improve the CH₄ selectivity and CO₂ utilization efficiency.

We report nanoarchitectonics of end-on conjugated metallopolymers by surface-initiated one-by-one electrochemical addition and assembly of bifunctional monomers with electroactive oxidation and reduction units under alternative positive and negative potentials. Rapid electrosynthesis can be potentially automated as an electrochemically assisted assembly or printing technique while reducing batch-to-batch variability.

A one-pot strategy for the stereospecific conversion of boronic esters into enones has been developed using methoxyallene as a commercially available, three-carbon building block. The methodology is suitable for primary, secondary, and tertiary boronic esters and has been applied to a 14-step total synthesis of the polyketide 10-deoxymethynolide.

HYPNOESYS (Hyperpolarized NOE System) has recently emerged as a promising approach to enhance the sensitivity of NMR spectroscopy in the solution state. We show that 2D NMR spectra can be obtained from HYPNOESYS-polarized samples, using single-scan acquisition methods, paving the way to a sensitive, information-rich and affordable analytical method.

A palladium-catalyzed skeletal rearrangement of 2-(2-allylarylsilyl)aryl triflates has been developed to give tetrahydrophenanthrosiloles via 1,5-C−Pd/C−Si bond exchange. The reaction pathways can be switched by tuning the reaction conditions to give fused dihydrodibenzosilepin derivatives from the same starting materials. The inspection of the reaction conditions revealed the importance of carboxylates in promoting the C−Pd/C−Si bond exchange.

Synergic interactions between nitrite anion and the thiocarbonyl functionality in various biologically relevant stable organosulfur motifs are shown to result in the formation of sulfane sulfur (S⁰) as well as NO gas. Spectroscopic investigations unequivocally suggest the involvement of metastable (per)thionitrite (SNO⁻/SSNO⁻) species.

A sudden operating temperature change (T pulse) results in a faster capacity fade of graphite|LiNi_0.8Mn_0.1Co_0.1O₂ (Gr|NMC811) pouch full cells. Comprehensive post-mortem analyses unveil that the T pulse mainly causes a deterioration of cathode-electrolyte interphase architecture and chemistry, which in turn accelerates anode-electrolyte interphase degradation due to aggregated chemical crossover from the cathode during long-term cycling.

The novel strontium nitridoborate hydride Sr₆N[BN₂]₂H₃ was obtained by a solid-state synthesis, extending the family of multinary hydrides. Single-crystal X-ray and neutron powder diffraction data revealed the crystal structure containing nitridoborate, nitride and hydride anions. Impedance spectroscopy shows hydride ion conductivity and MAS NMR as well as vibrational spectroscopy corroborate the structural analysis of our compound.

The first neutral and anionic square planar (sp) Pd(0) (ate) complexes are synthesized and fully characterized. Such species, which have been proposed as intermediates in Pd-catalyzed cross coupling reactions, are stabilized using a Si(IV) based Lewis acidic ambiphilic Z-type ligand, which causes a strong Pd−Si Z-type interaction as confirmed by DFT derived methods.

A breakthrough in room-temperature phosphorescence (RTP) emission performance was realized in a poly(vinylidene fluoride) (PVDF) matrix with a low glass transition temperature. Polymorph-dependent RTP emission in the PVDF matrix endows a 2.45 GHz microwave stimulus responsiveness to the material.

Tip-enhanced Raman spectroscopy (TERS) is used to map polyadenosine (polyA)-induced tau fibrils with nanoscale spatial resolution. It proves that polyA lies on the surface of the fibril core β-sheets but remains wrapped by the random-coiled fuzzy coat. TERS also shows the colocalization of positively charged amino acids with the anionic polyA cofactor, which is an important step to clarify the role of RNA cofactors in the fibril formation.

Single-scan ultraselective experiments, based on the GEMSTONE (gradient-enhanced multiplet-selective targeted-observation NMR experiment) element, are a powerful approach to extract detailed information from complex NMR spectra. We describe an approach allowing to dramatically reduce signal losses due to translational diffusion, for applications to structure elucidation and mixture analysis.

Negligible changes of flexible spacers enable remarkable change of supramolecular chirality and anisotropic topology in azobenzene polymer assemblies. The phase transition from amorphous to LC phase can cause the chiroptical inversion in supramolecular assemblies, leading to two types of chiral arrangements with opposite helicity.

Octadecahedron BiVO₄, which was obtained by facet engineering, was employed as a photochemical sensing material for the selective detection of H₂S at an ultralow concentration due to its larger proportion of (110) and (011) facets as well as the formation of the additional (111) facets. The insights into the interaction between H₂S and BiVO₄ under photoactivation were investigated.

A water-soluble tetrahedral Fe₄L₆ metal-organic cage has been successfully used to separate propane and propylene under ambient conditions. Mixed gases of C₃H₆ and C₃H₈ were captured by Fe₄L₆ at the gas-liquid interface in a U-shaped glass tube. Governed by the guest binding affinity, C₃H₆ is released first after transport of the gases to the receiving arm of the tube.

A new approach to the enantiocontrolled synthesis of α-amino ketone derivatives is disclosed by employing a nickel-catalyzed decarboxylative acylation strategy. Starting from readily available acyl chlorides and α-amino acids-derived redox-active esters, the reaction exhibits broad substrate scope, easy scalability, and is applied to dramatically simplify the synthesis of several known structures.

The origin of yellow-green room temperature phosphorescence (RTP) of triphenylamine from commercial sources has been clarified for the first time, which inspires a general and convenient approach to construct bicomponent host/guest organic RTP materials, that is, doping naphthyl substituted analogues into the host molecule.