• Issue

    Chemistry & Biodiversity: Volume 21, Issue 6

    June 2024
Previous Issue|Next Issue
Export Citation(s)Download PDF(s)

Covers

Free Access

Front Cover: Unlocking Quercetin's Neuroprotective Potential: A Focus on Bee-Collected Pollen (Chem. Biodiversity 6/2024)

Aleksandar Ž. Kostić,  Dılhun Keriman Arserim-Uçar,  Małgorzata Materska,  Barbara Sawicka,  Dominika Skiba,  Danijel D. Milinčić,  Mirjana B. Pešić,  Piotr Pszczółkowski,  Donya Moradi,  Parisa Ziarati,  Bernadetta Bienia,  Piotr Barbaś,  Mert Sudagıdan,  Preetinder Kaur,  Javad Sharifi-Rad, 
  • First Published: 18 June 2024
Front Cover: Unlocking Quercetin's Neuroprotective Potential: A Focus on Bee-Collected Pollen (Chem. Biodiversity 6/2024) Volume 21 Issue 6, 2024

Front Cover. Quercetin and its derivatives possessed strong activity against neuroinflammation. However, low bioaccessiblity limits their effectiveness. As a part of modern society strong urge to find potent natural sources of these compounds has raised. Among all, bee-collected pollen can be better source of quercetin/derivatives, compared to some usual food stuffs, as it is discussed and presented by Aleksandar Ž. Kostić, Javad Sharifi-Rad, and co-workers in their review article number 10.1002/cbdv.202400114.

Reviews

Unlocking Quercetin's Neuroprotective Potential: A Focus on Bee-Collected Pollen

Aleksandar Ž. Kostić,  Dılhun Keriman Arserim-Uçar,  Małgorzata Materska,  Barbara Sawicka,  Dominika Skiba,  Danijel D. Milinčić,  Mirjana B. Pešić,  Piotr Pszczółkowski,  Donya Moradi,  Parisa Ziarati,  Bernadetta Bienia,  Piotr Barbaś,  Mert Sudagıdan,  Preetinder Kaur,  Javad Sharifi-Rad, 
  • First Published: 22 February 2024
Unlocking Quercetin's Neuroprotective Potential: A Focus on Bee-Collected Pollen

A Review on the Chemical Properties, Plant Sources, Anti-shock Effects, Pharmacokinetics, Toxicity, and Clinical Applications of Anisodamine

Qiurui Xia,  Prof. Raoji Pingcuo,  Ce Yang,  Wei Xiong,  Xiaoyuan Peng,  Jing Xia,  Dr. Wenxiang Wang,  Prof. Meirong Hai, 
  • First Published: 28 February 2024
A Review on the Chemical Properties, Plant Sources, Anti-shock Effects, Pharmacokinetics, Toxicity, and Clinical Applications of Anisodamine

A Review on Traditional Uses, Phytochemistry, Pharmacology and Clinical Application of Tinospora sinensis (Lour.) Merr

Yan Liang,  Shao-Bo Guo,  Chang Xu,  Ying-Ying Su,  Cheng-Yuan Su,  Wei Zhang,  Bin Liu, 
  • First Published: 28 March 2024
A Review on Traditional Uses, Phytochemistry, Pharmacology and Clinical Application of Tinospora sinensis (Lour.) Merr

An Updated Review on Functionalized Graphene as Sensitive Materials in Sensing of Pesticides

Anirudh Pratap Singh Raman,  Gauri Thakur,  Garima Pandey,  Kamlesh Kumari,  Prashant Singh, 
  • First Published: 05 April 2024
An Updated Review on Functionalized Graphene as Sensitive Materials in Sensing of Pesticides

Chitosan and Chitooligosaccharides: Antifungal Potential and Structural Insights

Dr. Mayara Itala Geronimo de Azevedo,  Dr. Pedro Filho Noronha Souza,  Dr. José Edvar Monteiro Júnior,  Prof. Dr. Thalles Barbosa Grangeiro, 
  • First Published: 09 April 2024
Chitosan and Chitooligosaccharides: Antifungal Potential and Structural Insights

Delivery Strategies, Structural Modification, and Pharmacological Mechanisms of Honokiol: A Comprehensive Review

Congying Pan,  Qing Li,  Shuxin Xiong,  Yan Yang,  Yi Yang,  Prof. Chao Huang,  Prof. Zhi-Peng Wang, 
  • First Published: 02 February 2024
Delivery Strategies, Structural Modification, and Pharmacological Mechanisms of Honokiol: A Comprehensive Review

A New Insight Into The Huisgen Reaction: Heterogeneous Copper Catalyzed Azide-Alkyne Cycloaddition for the Synthesis of 1,4-Disubstituted Triazole (From 2018–2023)

Shivani Kasana,  Vaibhav Nigam,  Surbhi Singh,  Balak Das Kurmi,  Preeti Patel, 
  • First Published: 19 April 2024
A New Insight Into The Huisgen Reaction: Heterogeneous Copper Catalyzed Azide-Alkyne Cycloaddition for the Synthesis of 1,4-Disubstituted Triazole (From 2018–2023)

Benzimidazole and Benzoxazole Derivatives Against Alzheimer's Disease

Nagihan Faydalı,  Özlem Temiz Arpacı, 
  • First Published: 17 March 2024
Benzimidazole and Benzoxazole Derivatives Against Alzheimer's Disease

Sulfated Polysaccharides with Anticoagulant Potential: A Review Focusing on Structure-Activity Relationship and Action Mechanism

Qianfeng Chen,  Mengjiao Zhang,  Yue Liu,  Wei Liu,  Cheng Peng,  Lixue Zheng, 
  • First Published: 10 April 2024
Sulfated Polysaccharides with Anticoagulant Potential: A Review Focusing on Structure-Activity Relationship and Action Mechanism

Baccharoides anthelmintica (L.) Moench: A Review on Ethnomedicinal, Phytochemical, Pharmacological and Toxicological Profile

Vivek Singh Rajpoot,  Assist. Prof. Dr. Kareti Srinivasa Rao, 
  • First Published: 24 April 2024
Baccharoides anthelmintica (L.) Moench: A Review on Ethnomedicinal, Phytochemical, Pharmacological and Toxicological Profile

Open Access

Nα-Aroyl-N-Aryl-Phenylalanine Amides: A Promising Class of Antimycobacterial Agents Targeting the RNA Polymerase

Dr. Rüdiger W. Seidel,  Dr. Richard Goddard,  Markus Lang,  Dr. Adrian Richter, 
  • First Published: 08 April 2024
Nα-Aroyl-N-Aryl-Phenylalanine Amides: A Promising Class of Antimycobacterial Agents Targeting the RNA Polymerase

A Review on Ethnobotany, Phytochemistry and Pharmacological Activities of Euphorbia antiquorum L.

Lunasmrita Saikia,  Jyotirmoy Bhattacharyya,  Saikat Sen,  Partha Pratim Dutta, 
  • First Published: 05 April 2024
A Review on Ethnobotany, Phytochemistry and Pharmacological Activities of Euphorbia antiquorum L.

Plant-Derived Coumarins: A Narrative Review of Their Structural and Biomedical Diversity

Areej Hazem Younes,  Yasser Fakri Mustafa, 
  • First Published: 08 April 2024
Plant-Derived Coumarins: A Narrative Review of Their Structural and Biomedical Diversity

A Review on the Traditional Applications, Phytochemistry, and Pharmacology of the Genus Physochlaina G. Don

Dr. Younas Rasheed Tantray,  Ishrat Jan,  Irshad Mohiuddin,  Preeti Gorla,  Charul Anand,  Jagdish Chandra Arya,  Shahnawaz Ahmad Bhat,  Dr. Vijay Kumar,  Ch. Venkata Narasimhaji,  Shiddamallayya Nagayya,  Rabinarayan Acharya, 
  • First Published: 26 March 2024
A Review on the Traditional Applications, Phytochemistry, and Pharmacology of the Genus Physochlaina G. Don

Chemistry, Biological Activities, and Pharmacological Properties of Gastrodin: Mechanism Insights

Naoual El Menyiy,  Youssef Elouafy,  Rania Moubachir,  Rhizlan Abdnim,  Taoufiq Benali,  Douae Taha,  Asaad Khalid,  Ashraf N. Abdalla,  Siddiqa M. A. Hamza,  Salma Elhadi Ibrahim,  Mohamed El-Shazly,  Gokhan Zengin,  Abdelhakim Bouyahya, 
  • First Published: 04 April 2024
Chemistry, Biological Activities, and Pharmacological Properties of Gastrodin: Mechanism Insights

Advances and Strategies towards Synthesis of Aspidosperma Indole Alkaloids Goniomitine

Cong-Bin Ji, 
  • First Published: 08 April 2024
Advances and Strategies towards Synthesis of Aspidosperma Indole Alkaloids Goniomitine

Research Articles

Identification of an Alepterolic Acid Derivative as a Potent Anti-Breast-Cancer Agent via Inhibition of the Akt/p70S6K Signaling Pathway

Nina Wang,  Lei Zhang,  Junjie Yu,  Kaili Chang,  Minghui Fan,  Prof. Dr. Zi Liu,  Prof. Dr. Liang Ma,  Prof. Dr. Jianguo Cao,  Prof. Dr. Guozheng Huang, 
  • First Published: 22 September 2023
Identification of an Alepterolic Acid Derivative as a Potent Anti-Breast-Cancer Agent via Inhibition of the Akt/p70S6K Signaling Pathway

Antioxidant, Diabetic and Inflammatory Activities of Alpinia calcarata Roscoe Extract

Naorem Manglembi Devi,  Sankaranarayanan Nagarajan,  Chingakham Brajakishor Singh,  Mohammad Mujahid Ali Khan,  Anish Khan,  Nisha Khan,  Mohamed H. Mahmoud,  Hassan Fouad,  AbuZar Ansari, 
  • First Published: 16 September 2023
Antioxidant, Diabetic and Inflammatory Activities of Alpinia calcarata Roscoe Extract

Open Access

Metabolomic Diversity in Microbial Mats Under Different Environmental Conditions: A Tool to Test Microbial Ecosystem Chemical Change

BSc. Jhoselinne Buenrostro-Muñoz,  Dr. Scott A. Jarmusch,  Prof. Valeria Souza,  Dr. Anahí Martínez-Cárdenas,  Dr. Carlos A. Fajardo-Hernández,  MSc. Itzel R. Yeverino,  Prof. Luis E. Eguiarte,  Prof. Mario Figueroa, 
  • First Published: 18 September 2023
Metabolomic Diversity in Microbial Mats Under Different Environmental Conditions: A Tool to Test Microbial Ecosystem Chemical Change

Exploring the Synthetic and Antioxidant Potential of 1,2-Disubstituted Benzimidazoles Using [Et3NH][HSO4] Ionic Liquid Catalyst

Nusrat Sahiba,  Pankaj Teli,  Dr. Priyadarshi Meena,  Dr. Shikha Agarwal, 
  • First Published: 17 September 2023
Exploring the Synthetic and Antioxidant Potential of 1,2-Disubstituted Benzimidazoles Using [Et3NH][HSO4] Ionic Liquid Catalyst

Comparative Studies of Essential Oil Composition and Biological Activities of Callistemon citrinus from Western Himalaya

Sachin Vashisath,  Smita Kapoor,  Vandana Kumari,  Shabana Butt,  Prof. Dr. Dinesh Kumar, 
  • First Published: 20 September 2023
Comparative Studies of Essential Oil Composition and Biological Activities of Callistemon citrinus from Western Himalaya

Open Access

Forgotten Perfumery Plants - Part II: New Insights into the Development of Novel Fragrant Ingredients – Hawthorn Case Study

Dr. Anne-Sophie Bouville,  Kevin da Fonte,  Pascal Portes,  Jean-Charles Lhommet,  Prof. Stéphane Azoulay,  Prof. Xavier Fernandez, 
  • First Published: 10 October 2023
Forgotten Perfumery Plants - Part II: New Insights into the Development of Novel Fragrant Ingredients – Hawthorn Case Study

Essential Oils from Different Parts of Magnolia laevifolia: Chemical Constituents and Insecticidal Activities against Liposcelis bostrychophila

Jia-Wei Zhang,  Yi.-Xi Feng,  Yu Zheng,  Dr. Cheng-Fang Wang,  Dr. Shu-Shan Du, 
  • First Published: 16 September 2023
Essential Oils from Different Parts of Magnolia laevifolia: Chemical Constituents and Insecticidal Activities against Liposcelis bostrychophila

Microalgae Octapeptide IIAVEAGC Alleviates Oxidative Stress and Neurotoxicity in 6-OHDA-Induced SH-SY5Y Cells by Regulating the Nrf2/HO-1and Jak2/Stat3 Pathways

Yi Liu,  Liyuan Lin,  Haiyan Zheng,  Huixue Huang,  Zhong-Ji Qian, 
  • First Published: 09 April 2024
Microalgae Octapeptide IIAVEAGC Alleviates Oxidative Stress and Neurotoxicity in 6-OHDA-Induced SH-SY5Y Cells by Regulating the Nrf2/HO-1and Jak2/Stat3 Pathways

2,5-Thienylene-Strapped [26]Hexaphyrin as Multifunctional Chemosensor for Hg2+, Cu2+, and F− Ions

Dr. Bulti Abdisa Kerayu,  Prof. Chen-Hsiung Hung,  Dr. Anil Kumar Vardhaman,  Dr. Tibebu Alemu Ayanie,  Mr. Busha Jima Geneti, 
  • First Published: 24 February 2024
2,5-Thienylene-Strapped [26]Hexaphyrin as Multifunctional Chemosensor for Hg2+, Cu2+, and F− Ions

Antioxidant and Antimicrobial Potential of 1,8-Naphthyridine Based Scaffolds: Design, Synthesis and in Silico Simulation Studies within Topoisomerase II

Assoc. Prof. Dr. Nadia A. A. Elkanzi,  Assist. Prof. Dr. Hajer Hrichi,  Assist. Prof. Dr. Alaa Muqbil Alsirhani,  Assoc. Prof. Dr. Rania B. Bakr, 
  • First Published: 09 March 2024
Antioxidant and Antimicrobial Potential of 1,8-Naphthyridine Based Scaffolds: Design, Synthesis and in Silico Simulation Studies within Topoisomerase II

Revealing the 1H-NMR Profiling of Six Edible Mushrooms Consumed in the Northeastern Highlands of Puebla, Mexico

Dr. Yesenia Pacheco-Hernández,  Dr. Nemesio Villa-Ruano,  Dr. Edmundo Lozoya-Gloria,  MSc. Estefania de Jesús Terán-Sánchez,  Dr. Elvia Becerra-Martínez, 
  • First Published: 10 April 2024
Revealing the 1H-NMR Profiling of Six Edible Mushrooms Consumed in the Northeastern Highlands of Puebla, Mexico

Investigations of Limeum Indicum Plant for Diabetes Mellitus and Alzheimer's Disease Dual Therapy: Phytochemical, GC-MS Chemical Profiling, Enzyme Inhibition, Molecular Docking and In-Vivo Studies

Ms. Tahira Shamim,  Dr. Hafiz Muhammad Asif,  Dr. Syeda Abida Ejaz,  Mr. Zahid Hussain,  Prof. Dr. Tanveer A. Wani,  Ms. Laila Sumreen,  Dr. Muhammad Abdullah,  Mr. Zubair Ahmed,  Prof. Dr. Jamshed Iqbal,  Prof. Dr. Song Ja Kim,  Dr. Muhammad Kamal Shah, 
  • First Published: 12 April 2024
Investigations of Limeum Indicum Plant for Diabetes Mellitus and Alzheimer's Disease Dual Therapy: Phytochemical, GC-MS Chemical Profiling, Enzyme Inhibition, Molecular Docking and In-Vivo Studies

Carane-3,4-diol Derivatives as Potential Water-Based Herbicides

Yanqun Huang,  Maomao Zhu,  Hongyun Lan,  Daozhan Huang,  Mengna Lan,  Yanning Huang, 
  • First Published: 06 April 2024
Carane-3,4-diol Derivatives as Potential Water-Based Herbicides

A New Rare Halogenated Depside from Lichen and Study of its Anti-Proliferative Activity

Ajoy K. Bauri,  Ines Castro Dionicio,  Eric Salinas Arellano,  Jonathan G. Jeyaraj,  Sabine Foro,  Esperanza J. Carcache de Blanco, 
  • First Published: 15 March 2024
A New Rare Halogenated Depside from Lichen and Study of its Anti-Proliferative Activity

Computational Exploration of Naturally Occurring Flavonoids as TGF-β Inhibitors in Breast Cancer: Insights from Docking and Molecular Dynamics Simulations and In-vitro Cytotoxicity Study

Assoc. Prof. Umang Shah,  Niyati Patel,  Assoc. Prof. Mehul Patel,  Shishir Rohit,  Assoc. Prof. Nilay Solanki,  Assist. Prof. Ashish Patel,  Assist. Prof. Swayamprakash Patel,  Vishwa Patel,  Rajvi Patel,  Assoc. Prof. Rahul D. Jawarkar, 
  • First Published: 16 April 2024
Computational Exploration of Naturally Occurring Flavonoids as TGF-β Inhibitors in Breast Cancer: Insights from Docking and Molecular Dynamics Simulations and In-vitro Cytotoxicity Study

Diterpenoid Alkaloids from Delphinium liangshanense

Yue Liu,  Yi-Dan Zhao,  He-Yang Zhong,  Si-Yang Chen,  Shuai Huang,  Lin Chen,  Xian-Li Zhou, 
  • First Published: 08 January 2024
Diterpenoid Alkaloids from Delphinium liangshanense

Synthesis, Characterization and Evaluation of the Antimicrobial and Herbicidal Activities of Some Transition Metal Ions Complexes with the Tranexamic Acid

Amira A. Mohamed,  Sadeek A. Sadeek,  Nihad G. Rashid,  Hazem S. Elshafie,  Ippolito Camele, 
  • First Published: 29 April 2024
Synthesis, Characterization and Evaluation of the Antimicrobial and Herbicidal Activities of Some Transition Metal Ions Complexes with the Tranexamic Acid

Cytotoxicity and Biological Activities of Geopopolis Extract from the Stingless bee (Melipona scutellaris) in Isolates of Staphylococcus aureus

Maria Gabriella da Silva Albuquerque Borges,  Luanna de Oliveira e Lima,  Ana Caroline Meneses Ferreira Veras,  Rafael Carlos Ferreira,  Danielle da Nóbrega Alves,  Isac Almeida de Medeiros,  Marciane Magnani,  Marianna Vieira Sobral,  Ricardo Dias de Castro,  Saulo Relison Tintino,  Cícera Datiane de Morais Oliveira-Tintino,  Henrique Douglas Melo Coutinho,  Felipe Queiroga Sarmento Guerra,  Daniela Bomfim de Barros,  Maria Betânia Melo de Oliveira, 
  • First Published: 12 April 2024
Cytotoxicity and Biological Activities of Geopopolis Extract from the Stingless bee (Melipona scutellaris) in Isolates of Staphylococcus aureus

One Pot Synthesis and Biological Activity Studies of New Spirooxindoles

M. S. Stu. Amir Reza Omidvar,  Prof. Dr. Sakineh Asghari,  Dr. Leila Ghasempour,  Dr. Mojtaba Mohseni, 
  • First Published: 23 February 2024
One Pot Synthesis and Biological Activity Studies of New Spirooxindoles

Synthesis and Antifungal Activity of Norbornene Carboxamide/sulfonamide Derivatives as Potential Fungicides Targeting Laccase

Zi-Hui Yang,  Yi-Gui Qiu,  Dao-Jun Jin,  Yi-Ming Zheng,  Jia Li,  Wen Gu, 
  • First Published: 14 April 2024
Synthesis and Antifungal Activity of Norbornene Carboxamide/sulfonamide Derivatives as Potential Fungicides Targeting Laccase

Hot Paper

Rosa laevigata Polysaccharides Ameliorate Dextran Sulfate Sodium-Induced Ulcerative Colitis of Beagles through Regulating Gut Microbiota

Song Peng,  Xuanqi Lu,  Fangzhu Lin,  Ningning Mao,  Lin Yu,  Tianyu Zhu,  Jing He,  Yang Yang,  Zhenguang Liu,  Deyun Wang, 
  • First Published: 03 April 2024
Rosa laevigata Polysaccharides Ameliorate Dextran Sulfate Sodium-Induced Ulcerative Colitis of Beagles through Regulating Gut Microbiota

Bioactive Profiling, Antibacterial Efficacy and Computational Modelling of Myrtus Communis Essential Oil (Morocco)

Dr. Mouhcine Hayani,  Dr. Tariq Benabbouha,  Dr. Nidal Naceiri Mrabti,  Dr. Said Eljebri,  Dr. Maryame Sabiri,  Prof. Touriya Zair, 
  • First Published: 30 April 2024
Bioactive Profiling, Antibacterial Efficacy and Computational Modelling of Myrtus Communis Essential Oil (Morocco)

Determination of Bacterial Community Structure of Table Olive via Metagenomic Approach in Şarköy

Samet Ucak, 
  • First Published: 13 April 2024
Determination of Bacterial Community Structure of Table Olive via Metagenomic Approach in Şarköy

Bioactives of Melipona rufiventris Propolis: Exploring its Antimicrobial, Anti-Inflammatory, and Antioxidant Activities

Amanda Tristão Santini,  Rayra Annara Otacílio Pinto,  Josy Goldoni Lazarini,  Daniel Vieira de Morais,  Anna Maria Alves de Piloto Fernandes,  Marcelo Franchin,  Patrícia Lunardelli Negreiros de Carvalho,  Carolina Girotto Pressete,  Pedro Luiz Rosalen,  Severino Matias de Alencar,  Patrícia de Oliveira Carvalho,  Marisa Ionta,  Masaharu Ikegaki, 
  • First Published: 17 April 2024
Bioactives of Melipona rufiventris Propolis: Exploring its Antimicrobial, Anti-Inflammatory, and Antioxidant Activities

Phyto-Fabrication of Moringa Oleifera Peel-Sourced Silver Nanoparticles: A Promising Approach for Combating Hepatic Cancer by Targeting Proinflammatory Cytokines and Mitigating Cytokine Storms

Shahnawaz Sameem,  Vivek Dwivedi,  Vikas Kumar,  Ashish R. Dwivedi,  Assoc. Prof. Dr. Prateek Pathak,  Bhupendra Singh,  Mashooq Ahmad Bhat,  Prof. Dr. Amita Verma, 
  • First Published: 07 April 2024
Phyto-Fabrication of Moringa Oleifera Peel-Sourced Silver Nanoparticles: A Promising Approach for Combating Hepatic Cancer by Targeting Proinflammatory Cytokines and Mitigating Cytokine Storms

Potentialities of Dandelion (Taraxacum Mongolicum Hand.-Mazz.) Flower Extracts on Gastric Protection against Helicobacter Pylori and Characterization of its Bioactive Constituents

Huirong Dong,  Jiasen Qiao,  Shengyao Hou,  Haoqi Ran,  Weihao Sun,  Benfan Lin,  Yanchun Han,  Dr. Chen Yu,  Dr. Yanni Li, 
  • First Published: 03 April 2024
Potentialities of Dandelion (Taraxacum Mongolicum Hand.-Mazz.) Flower Extracts on Gastric Protection against Helicobacter Pylori and Characterization of its Bioactive Constituents

Extraction of Lentinus Edodes Polysaccharides with Ultrasound Enhanced with Deep Eutectic Solvent and Their Structural Characterization and Antioxidant Activity

Jixian Zhang,  Xinglin Zeng,  Guoyan Liu,  Chaoting Wen,  Xin Xu, 
  • First Published: 04 April 2024
Extraction of Lentinus Edodes Polysaccharides with Ultrasound Enhanced with Deep Eutectic Solvent and Their Structural Characterization and Antioxidant Activity

Wound Healing Activity of Topical Herbal Gels Containing Barringtonia acutangula Fruit Extract: In silico and In vivo Studies

Kumari Priyanka,  Rudra Narayan Sahoo,  Ashirbad Nanda,  Satish Kanhar,  Chandan Das,  Abhijit Sahu,  Pradeep Kumar Naik,  Amit Kumar Nayak, 
  • First Published: 30 April 2024
Wound Healing Activity of Topical Herbal Gels Containing Barringtonia acutangula Fruit Extract: In silico and In vivo Studies

Production of Aromatic Hydrocarbons from Co-Hydropyrolysis of Biomass Components and HDPE with Application of Modified HZSM-5 Catalyst

Long Ren,  Yupu Xu,  Wenjun Chen,  Changsen Zhang, 
  • First Published: 28 March 2024
Production of Aromatic Hydrocarbons from Co-Hydropyrolysis of Biomass Components and HDPE with Application of Modified HZSM-5 Catalyst

Impact of Fermentation on the Phytochemical Profile and Bioactivity Characteristics of Aqueous Matricaria recutita L. Root Extracts

Lilo K. Mailänder,  Khadijeh Nosrati Gazafroudi,  Marit Greiß,  Dr. Peter Lorenz,  Sven Nicolay,  Prof. Dr. Carsten Gründemann,  Prof. Dr. Florian C. Stintzing,  Prof. Dr. Rolf Daniels,  Prof. Dr. Dietmar R. Kammerer, 
  • First Published: 02 April 2024
Impact of Fermentation on the Phytochemical Profile and Bioactivity Characteristics of Aqueous Matricaria recutita L. Root Extracts

Ring-Contracted Artemisinin Derivatives as Novel CDK 4/6 Inhibitors: Synthesis and Anti-Breast Cancer Evaluation

Jun-Jie Zhu,  Yi Ai,  Jun-Hui Wu,  Chang-Guang Zeng,  Zhen Cui,  Zheng-Ping Zhang,  Jia-Yi Zhu,  Chang-Qi Wang,  Assoc. Prof. Hang Zhong, 
  • First Published: 15 April 2024
Ring-Contracted Artemisinin Derivatives as Novel CDK 4/6 Inhibitors: Synthesis and Anti-Breast Cancer Evaluation

Construction and Docking Studies of Novel Pyrimido[4,5-b]quinolines as Antimicrobial Agents

Assoc. Prof. Dr. Rania B. Bakr,  Prof. Dr. Islam H. El Azab,  Prof. Dr. Nadia A. A. Elkanzi, 
  • First Published: 03 April 2024
Construction and Docking Studies of Novel Pyrimido[4,5-b]quinolines as Antimicrobial Agents

Identifying Anti-NSCLC Bioactive Compounds in Scutellaria via 2D NMR-Based Metabolomic Analysis of Pharmacologically Classified Crude Extracts

Jialuo Chen,  Yanping Li,  Xiu Gu,  Tianren Wu,  Huan Du,  Caihong Bai,  Jiahui Yang,  Kaifeng Hu, 
  • First Published: 05 April 2024
Identifying Anti-NSCLC Bioactive Compounds in Scutellaria via 2D NMR-Based Metabolomic Analysis of Pharmacologically Classified Crude Extracts

Protective Effects of Tunisian Orange Co-Product Extract and Oleuropein-Hesperidin Combination on Bleomycin-Induced Pulmonary Fibrosis in Rats

Ben Abdallah Mariem,  Bahri Sana,  Nahdi Afef,  Mlika Mona,  Hadjkacem Linda,  Jameleddine Saloua,  Boudhrioua Nourhene, 
  • First Published: 12 April 2024
Protective Effects of Tunisian Orange Co-Product Extract and Oleuropein-Hesperidin Combination on Bleomycin-Induced Pulmonary Fibrosis in Rats

Synthesis and Inhibitor Effect Novel Alkoxymethyl Derivatives of Dihetero Cycloalkanes on Carbonic Anhydrase and Acetylcholinesterase

Vagif Farzaliyev,  Adem Ertürk,  Malahat Abbasova,  Oruj Nabiyev,  Dr. Yeliz Demir,  Hatice Kızıltaş,  Afsun Sujayev,  İlhami Gülçin, 
  • First Published: 04 April 2024
Synthesis and Inhibitor Effect Novel Alkoxymethyl Derivatives of Dihetero Cycloalkanes on Carbonic Anhydrase and Acetylcholinesterase

Synthesis, Characterization, Molecular Docking, and Investigation of Antibacterial Properties of New Derivatives of 1-H-Phenanthro [9,10-d] Imidazole

Nosrat O. Mahmoodi,  Anahita Rajabi,  Hadiseh Yazdani Nyaki,  Hossein Taherpour Nahzomi, 
  • First Published: 18 April 2024
Synthesis, Characterization, Molecular Docking, and Investigation of Antibacterial Properties of New Derivatives of 1-H-Phenanthro [9,10-d] Imidazole

Four New Isocoumarins from the Mangrove Fungus Alternaria Malorum with Antimicrobial Activities

Wei Fan,  Prof. Dr. Yiwen Tao,  Canmin Jiang,  Qisen Huang,  Jiacong Li,  Dr. Weijia Ding,  Prof. Dr. Chunyuan Li, 
  • First Published: 06 March 2024
Four New Isocoumarins from the Mangrove Fungus Alternaria Malorum with Antimicrobial Activities

GC-MS AND Chemometric Analysis of the Essential Oils Obtained from Mexican Commercial Chamomilla Recutita Teas

Araceli Pérez-Vásquez,  Araceli Peña-Álvarez,  Prof. Rachel Mata, 
  • First Published: 19 March 2024
GC-MS AND Chemometric Analysis of the Essential Oils Obtained from Mexican Commercial Chamomilla Recutita Teas

Triterpene Glycosides from the Viscera of Sea Cucumber Apostichopus japonicus with Embryotoxicity

Yanfang Liu,  Zhen Lu,  Zhi Yan,  Xiaodong Li,  Xiuli Yin,  Ranran Zhang,  Yaxi Li,  Song Wang,  Ruliang Xie,  Ke Li, 
  • First Published: 08 March 2024
Triterpene Glycosides from the Viscera of Sea Cucumber Apostichopus japonicus with Embryotoxicity

Porphysome Engineered With Specific Protein Binding Sites as a Multimodal Theranostic Nanocarrier for Targeted Protein Delivery

Mrs. Niloofar Ayyari,  Dr. Zahra Vaezi,  Mrs. Zeinab Fotouhi Ashin,  Dr. Elham Karimi,  Mrs. Fatemeh Mohsenzadeh haji,  Dr. Maryam Nikkhah,  Prof. Hossein Naderi-Manesh, 
  • First Published: 14 April 2024
Porphysome Engineered With Specific Protein Binding Sites as a Multimodal Theranostic Nanocarrier for Targeted Protein Delivery

Transforming Pharmaceutical Synthesis with Sein-E-B Nanocomposite Photocatalyst through 1,4-NAD(P)H Cofactor Regeneration and C-N Bond Activation

Ravindra K. Shukla,  Rajesh K. Yadav,  Vitthal L. Gole,  Rajat Singhal,  Rehana Shahin,  Shaifali Mishra,  Satyam Singh,  Kanchan Sharma,  Jin-Ook Baeg,  Gamal A. El-Hiti,  Krishna Kumar Yadav,  Navneet Kumar Gupta, 
  • First Published: 08 April 2024
Transforming Pharmaceutical Synthesis with Sein-E-B Nanocomposite Photocatalyst through 1,4-NAD(P)H Cofactor Regeneration and C-N Bond Activation

Physicochemical Characterization, Antioxidant and Tyrosinase Inhibitory Activities of Coffea Robusta Monofloral Honey from Dak Lak Province, Vietnam

Quang-Vinh Nguyen,  Minh-Trung Nguyen,  Bich Huyen Bui Thi,  Quoc-Quan Mai,  Manh-Dung Doan,  Thi-Huyen Nguyen,  Phuoc-Vinh Nguyen,  Tri-Nhut Pham,  Tam Minh Le, 
  • First Published: 14 May 2024
Physicochemical Characterization, Antioxidant and Tyrosinase Inhibitory Activities of Coffea Robusta Monofloral Honey from Dak Lak Province, Vietnam

Untargeted Metabolomic to Access Chemical Differences Induced by Dual Endophyte Cultures Isolated from Euphorbia Umbellata

Amanda Santos Gusmão,  João Carlos Silva Conceição,  Stefane Moreira de Queiros Santos,  Cecilia Lima Sampaio Pereira,  Douglas Siqueira de Almeida Chaves,  Karen de Jesus Nicácio,  Daniela Aparecida Chagas-Paula,  Eliane de Oliveira Silva, 
  • First Published: 16 April 2024
Untargeted Metabolomic to Access Chemical Differences Induced by Dual Endophyte Cultures Isolated from Euphorbia Umbellata

Open Access

The First Comprehensive Chemical Profiling of Vachellia gummifera (Willd.) Kyal. & Boatwr., a Plant with Medicinal Value

Musa Kisiriko,  Clarice Noleto-Dias,  Gabin T. M. Bitchagno,  Imane Naboulsi,  Maria Anastasiadi,  Leon A. Terry,  Mansour Sobeh,  Michael H. Beale,  Jane L. Ward, 
  • First Published: 19 March 2024
The First Comprehensive Chemical Profiling of Vachellia gummifera (Willd.) Kyal. & Boatwr., a Plant with Medicinal Value

Flavonoids From the Aerial Parts of Sophora tonkinensis and Their Potential Anti-Inflammatory Activities

Qing-Qing Yang,  Yan-Fei Yang,  Xuan-Qin Chen,  Rong-Tao Li,  Zhi-Jun Zhang, 
  • First Published: 18 April 2024
Flavonoids From the Aerial Parts of Sophora tonkinensis and Their Potential Anti-Inflammatory Activities

Synthesis, Structural Characterization, and Biological Activities of 1,3,4- Thiadiazole Derivatives Containing Sulfonylpiperazine Structures

You-hua Liu,  Fa-li Wang,  Xiao-li Ren,  Chang-kun Li,  Lin-hong Jin,  Xia Zhou, 
  • First Published: 05 March 2024
Synthesis, Structural Characterization, and Biological Activities of 1,3,4- Thiadiazole Derivatives Containing Sulfonylpiperazine Structures

Phytochemical Profile, Antioxidant, Enzyme Inhibition, Acute Toxicity, In Silico Molecular Docking and Dynamic Analysis of Apis Mellifera Propolis as Antidiabetic Supplement

Putri Hawa Syaifie,  Delfritama Ibadillah,  Muhammad Miftah Jauhar,  Rikania Reninta,  Sri Ningsih,  Donny Ramadhan,  Adzani Gaisani Arda,  Dhecella Winy Cintya Ningrum,  Nofa Mardia Ningsih Kaswati,  Nurul Taufiqu Rochman,  Etik Mardliyati, 
  • First Published: 07 April 2024
Phytochemical Profile, Antioxidant, Enzyme Inhibition, Acute Toxicity, In Silico Molecular Docking and Dynamic Analysis of Apis Mellifera Propolis as Antidiabetic Supplement

Exploration of Some Heterocyclic Compounds Containing Trifluoromethylpyridine Scaffold as Insecticides Toward Aphis gossypii Insects

Mohamed A. Gad,  Moustafa M. S. Bakry,  Eman F. M. Tolba,  Abeer M. Alkhaibari,  Abadi M. Mashlawi,  Marwa A. Thabet,  Elham A. Al-Taifi,  Etify A. Bakhite, 
  • First Published: 31 March 2024
Exploration of Some Heterocyclic Compounds Containing Trifluoromethylpyridine Scaffold as Insecticides Toward Aphis gossypii Insects

Open Access

Design, Synthesis and Biological Evaluation of Novel Gypsogenin Derivatives as Potential Anticancer and Antimicrobial Agents

Safiye Emirdağ,  Nafia Gökçe Ulusoy,  Mehran Aksel, 
  • First Published: 09 April 2024
Design, Synthesis and Biological Evaluation of Novel Gypsogenin Derivatives as Potential Anticancer and Antimicrobial Agents

Synthesis, Biological and Molecular Docking Studies of Thiazole-Thiadiazole derivatives as potential Anti-Tuberculosis Agents

A. Prof. Samin A. Shaikh,  Dr. Shivaji R. Labhade,  Dr. Raju R. Kale,  A. Prof. Prajakta Y. Pachorkar,  Dr. Rohan J. Meshram,  R. Scholar. Kamlesh S. Jain,  A. Prof. Hrishikesh S. Labhade,  Dr. Deepak R. Boraste,  Dr. Rahul A. More,  Dr. Santosh S. Chobe,  R. Scholar. Debopriya Ballabh,  Dr. Satish N. Wakchaure, 
  • First Published: 03 May 2024
Synthesis, Biological and Molecular Docking Studies of Thiazole-Thiadiazole derivatives as potential Anti-Tuberculosis Agents

Chemical Constituents from the deep-sea-derived Fungus Aureobasidium melanogenum LUO5

Hao-Yu Dong,  Yuan Wang,  Xiao-Yu Zhang,  Meng Zhang,  Long-He Yang,  Zheng-Biao Zou,  You Li,  Ming-Min Xie,  Xian-Wen Yang,  Bin Wang, 
  • First Published: 12 April 2024
Chemical Constituents from the deep-sea-derived Fungus Aureobasidium melanogenum LUO5

Two Undescribed Germacrane-Type Sesquiterpenoids from Salvia cavaleriei var. simplicifolia Stib. and Their Anti-Alzheimer's Disease Activity

Qian Wu,  Li Liu,  Yu-Bin Lu,  Le-Le Guo,  Mi-Na Yang,  Hui-Jie Li,  Chun-Min Liu,  Li-Jia Ye,  Zhan-Xin Zhang,  Yong-Liang Shao,  Dong-Qing Fei, 
  • First Published: 27 March 2024
Two Undescribed Germacrane-Type Sesquiterpenoids from Salvia cavaleriei var. simplicifolia Stib. and Their Anti-Alzheimer's Disease Activity

New Antibacterial 1,3,4-Thiadiazole Derivatives With Pyridine Moiety

Nesrin Şener,  Aiman Emhemad Omeran Aldwib, 
  • First Published: 12 April 2024
New Antibacterial 1,3,4-Thiadiazole Derivatives With Pyridine Moiety

Two New Phenylpropanoid Compounds from Lilium Brownii and Their Anti-monoamine Oxidase Activity

Chengcheng Hui,  Shuaibo He,  Mengshan Ji,  Yuhang Zhang,  Haibo Wang,  Xiaowei Wang,  Tao Guo, 
  • First Published: 18 April 2024
Two New Phenylpropanoid Compounds from Lilium Brownii and Their Anti-monoamine Oxidase Activity

Active Constituents with Tyrosinase Inhibitory Activities from Waste Tobacco Leaves

Mei Zhang,  Jia-Yu Sun,  Hong-Mao Qiu,  Peng Zhang,  Lu-Lu Deng,  Jiang Li,  Xiao-Jiang Hao,  Xian-Kun Su,  Shu-Zhen Mu, 
  • First Published: 12 April 2024
Active Constituents with Tyrosinase Inhibitory Activities from Waste Tobacco Leaves

Anti-inflammatory Steroids from the South China Sea Sponge Spongia officinalis

Jiao Liu,  Zi-Yi Liu,  Yan Fu,  Yu-Cheng Gu,  Song-Wei Li,  Hai-Yan Zhang,  Yue-Wei Guo, 
  • First Published: 04 April 2024
Anti-inflammatory Steroids from the South China Sea Sponge Spongia officinalis

Diaporchalasins A–E, New Cytochalasins from the Endophytic Fungus Diaporthe sp. BMX12 Isolated from Aquilaria sinensis

Li Yang,  Qi Wang,  Qing-Yun Ma,  Qing-Yi Xie,  Cui-Juan Gai,  You-Gen Wu,  Hao-Fu Dai,  You-Xing Zhao, 
  • First Published: 11 April 2024
Diaporchalasins A–E, New Cytochalasins from the Endophytic Fungus Diaporthe sp. BMX12 Isolated from Aquilaria sinensis

Synergistic Inhibitions of Gram-Negative Bacteria by Combination Treatment with Ciprofloxacin and a Novel Glucolipid

Liyuan Yang,  Qingqing Zhang,  Deng Yu,  Weiming Zhu,  Yi Wang, 
  • First Published: 17 April 2024
Synergistic Inhibitions of Gram-Negative Bacteria by Combination Treatment with Ciprofloxacin and a Novel Glucolipid

New Hydroxyphenylacetic Acids and α-Pyrone Derivative from the Deep-Sea Cold Seep Sediment-Derived Fungus Penicillium corylophilum CS-682

Chi-Sheng Zhu,  Xiao-Ming Li,  Sui-Qun Yang,  Yi-Wei Liu,  Bin-Gui Wang,  Xin Li, 
  • First Published: 27 March 2024
New Hydroxyphenylacetic Acids and α-Pyrone Derivative from the Deep-Sea Cold Seep Sediment-Derived Fungus Penicillium corylophilum CS-682

Unveiling the Biomedical Applications of Novel Coumarins Isolated From Capsicum Annuum L. Seeds by a Multivariate Extraction Technique

Areej Hazem Younes,  Yasser Fakri Mustafa, 
  • First Published: 15 April 2024
Unveiling the Biomedical Applications of Novel Coumarins Isolated From Capsicum Annuum L. Seeds by a Multivariate Extraction Technique

Exploring Steroidal Saponin Composition and Morphometric Characteristics of Rhizomes from Trillium govanianum Wall. ex D. Don: Inference for Medicinal Properties and Genetic Stock Improvement

Surendra Singh Bisht,  Rajendra K. Meena,  Maneesh S. Bhandari,  Prithvi Pal Singh,  Upendra Sharma,  Aman Bisht,  Praveen K. Verma, 
  • First Published: 23 April 2024
Exploring Steroidal Saponin Composition and Morphometric Characteristics of Rhizomes from Trillium govanianum Wall. ex D. Don: Inference for Medicinal Properties and Genetic Stock Improvement

Synthesis and Antifungal Activity of Coumarin Derivatives Containing Hydrazone Moiety

Zibo Zhang,  Dongxian Geng,  Zhou Yang,  Prof. Le Pan,  Prof. Lu Jin, 
  • First Published: 08 April 2024
Synthesis and Antifungal Activity of Coumarin Derivatives Containing Hydrazone Moiety

Metabolomic Profiling and DNA-Fingerprinting of Newly Recorded White-Flowered Populations of Salvia lanigera Poir. in Egypt

Mai M. Farid,  Mona M. Marzouk,  Viktoria Ivanova,  Paraskev Nedialkov,  Mona O. El Shabrawy,  Salwa A. Kawashty,  Mahmoud M. Sakr,  Sameh R. Hussein,  Antoaneta Trendafilova, 
  • First Published: 29 April 2024
Metabolomic Profiling and DNA-Fingerprinting of Newly Recorded White-Flowered Populations of Salvia lanigera Poir. in Egypt