Volume 21, Issue 6 e202400329
Research Article

Transforming Pharmaceutical Synthesis with Sein-E-B Nanocomposite Photocatalyst through 1,4-NAD(P)H Cofactor Regeneration and C-N Bond Activation

Ravindra K. Shukla

Ravindra K. Shukla

Department of Chemistry and Environmental Science, Madan Mohan Malaviya University of Technology, Gorakhpur, U.P., 273010 India

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Rajesh K. Yadav

Corresponding Author

Rajesh K. Yadav

Department of Chemistry and Environmental Science, Madan Mohan Malaviya University of Technology, Gorakhpur, U.P., 273010 India

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Vitthal L. Gole

Vitthal L. Gole

Department of Chemical Engineering, Madan Mohan Malaviya University of Technology, Gorakhpur, 273010 U.P., India

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Rajat Singhal

Rajat Singhal

Centre for Sustainable Technologies, Indian Institute of Science, Gulmohar Marg, Mathikere, Bengaluru, 560012 India

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Rehana Shahin

Rehana Shahin

Department of Chemistry and Environmental Science, Madan Mohan Malaviya University of Technology, Gorakhpur, U.P., 273010 India

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Shaifali Mishra

Shaifali Mishra

Department of Chemistry and Environmental Science, Madan Mohan Malaviya University of Technology, Gorakhpur, U.P., 273010 India

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Satyam Singh

Satyam Singh

Department of Chemistry and Environmental Science, Madan Mohan Malaviya University of Technology, Gorakhpur, U.P., 273010 India

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Kanchan Sharma

Kanchan Sharma

Department of Chemistry and Environmental Science, Madan Mohan Malaviya University of Technology, Gorakhpur, U.P., 273010 India

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Jin-Ook Baeg

Corresponding Author

Jin-Ook Baeg

Artificial Photosynthesis Research group, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon, 34114 Republic of Korea

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Gamal A. El-Hiti

Gamal A. El-Hiti

Department of Optometry, College of Applied, Medical Sciences, King Saud University, Riyadh, 11433 Saudi Arabia

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Krishna Kumar Yadav

Krishna Kumar Yadav

Faculty of Science and Technology, Madhyanchal Professional University, Ratibad, Bhopal, 462044 India

Environmental and Atmospheric Sciences Research Group, Scientific Research Center, Al-Ayen University, Thi-Qar, Nasiriyah, 64001 Iraq

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Navneet Kumar Gupta

Corresponding Author

Navneet Kumar Gupta

Centre for Sustainable Technologies, Indian Institute of Science, Gulmohar Marg, Mathikere, Bengaluru, 560012 India

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First published: 08 April 2024

Abstract

The need for sunlight chemical renewal and contemporary organic transformation has fostered the advancement of environmentally friendly photocatalytic techniques. For the first time, we report on the novel crafting of a bright future with selenium-infused Eosin-B (Sein-E-B) nanocomposite photocatalysts in this work. The Sein-E-B nanocomposite materials were created using a hydrothermal process for solar chemical regeneration and organic transformation under visible light. The synthesized samples were subjected to UV-DRS-visible spectroscopy, FT-IR, SEM, EDX, EIS and XRD analysis. The energy band gap of the Sein-E-B nanocomposite photocatalyst was measured using UV-DRS, and the result was around 2.06 eV. to investigate the generated Sein-E-B catalytic activity as a nanocomposite for 1,4-NADH/NADPH re-formation and C−N bond activation. This novel photocatalyst offers a promising alternative for the regeneration of solar chemicals and C−N bond creation between pyrrole and aryl halides.

Graphical Abstract

Conflict of interests

The authors declare no conflict of interest.

Data Availability Statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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