Volume 21, Issue 6 e202301923
Research Article

Diterpenoid Alkaloids from Delphinium liangshanense

Yue Liu

Yue Liu

School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 Sichuan, People's Republic of China

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Yi-Dan Zhao

Yi-Dan Zhao

School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 Sichuan, People's Republic of China

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He-Yang Zhong

He-Yang Zhong

School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 Sichuan, People's Republic of China

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Si-Yang Chen

Si-Yang Chen

School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 Sichuan, People's Republic of China

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Shuai Huang

Shuai Huang

School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 Sichuan, People's Republic of China

School of Life Science and Engineering, Yibin Institute of Southwest Jiaotong University, Yibin, 644000 Sichuan, People's Republic of China

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Lin Chen

Lin Chen

School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 Sichuan, People's Republic of China

School of Life Science and Engineering, Yibin Institute of Southwest Jiaotong University, Yibin, 644000 Sichuan, People's Republic of China

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Xian-Li Zhou

Corresponding Author

Xian-Li Zhou

School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 Sichuan, People's Republic of China

Affiliated Hospital of Southwest Jiaotong University & The Third People Hospital of Chengdu, Chengdu, 610031 Sichuan, People's Republic of China

School of Life Science and Engineering, Yibin Institute of Southwest Jiaotong University, Yibin, 644000 Sichuan, People's Republic of China

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First published: 08 January 2024
Citations: 1

Abstract

Two new C19-diterpenoid alkaloids of the lycoctonine-type (liangshanine A and liangshanine B) and nineteen known compounds (3-21) were isolated from the whole plant of Delphinium liangshanense W. T. Wang, and all the compounds were identified by different spectroscopic analyses, such as IR, HR-ESI-MS and NMR. All the compounds were isolated from this plant for the first time and tested for the anti-proliferation effects on MH7 A and SF9 cells to figure their anti-rheumatoid arthritis and anti-insect activity, but none of them showed remarkable activity.

Graphical Abstract

Conflict of interests

The authors declare no conflict of interest.

Data Availability Statement

The detailed data on the results of this study can be found in the supplement to this article.

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