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    2025
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Research Article
Open Access

Molecular and Cellular Insights Into Retinoblastoma: Pathways, Immune Landscape, and Therapeutic Opportunities

Yixu Wang,  Yumeng Quan,  Shuyan Zhou,  Yufei Dang,  Xiaoxia Zhang,  Cheng Pei, 
  • First Published: 22 July 2025
Research Article
Open Access

A Comparative Study of the HbA1c Level in Prediabetic Patients With Lifestyle Modification Versus Oral Hypoglycemic Agents

Raj Kumar Thapa,  Kushal Shrestha,  Kanchan K. C.,  Sirapa Maharjan,  Shashwot Sedhain,  Reshu B. K.,  Sitaram Khadka, 
  • First Published: 21 July 2025
Research Article
Open Access

Study on the Efficacy and Safety of Off-Label Dosing of Rivaroxaban in Chinese Nonvalvular Atrial Fibrillation Patients

Zhe Jiang,  Wenmin Dong,  Xiaoxiao Lu,  Xiaolin Liu,  Jingru Gong, 
  • First Published: 21 July 2025
Research Article
Open Access

Pharmacokinetics/Pharmacodynamics and Therapeutic Drug Monitoring of Ceftazidime/Avibactam in Patients With Gram-Negative Bacterial Infections

Ruiying Han,  Dan Sun,  Ying Zhang,  Baosen Yue,  Taotao Wang, 
  • First Published: 16 July 2025
Research Article
Open Access

Impact of Direct-Acting Antiviral Therapy on Tacrolimus Pharmacokinetics in Hepatitis C Virus Nucleic Acid Testing-Positive Transplant Recipients

Jared Walz,  Glen Leverson,  Lily Stalter,  John Rice,  David Al-Adra,  Joshua J. Wiegel, 
  • First Published: 21 June 2025
Research Article
Open Access

Exploring Opportunities for Improving Pharmacy Services for People With Disabilities: A Qualitative Study

Nasser M. Alorfi,  Ahmed M. Ashour,  Fahad S. Alshehri,  Saad M. Wali,  Maan H. Harbi,  Mohammed M. Aldurdunji,  Shaker T. Alsharif,  Reem Hasaballah Alhasani,  Mohammed S. Alharthi,  Nasser M. Aldekhail, 
  • First Published: 20 June 2025
Research Article
Open Access

Does Unidirectional Buccal Patches Loaded With Lidocaine and Dexmedetomidine Ameliorate Injection Pain in Dental Procedures? A Double-Blinded Randomized Controlled Trial

Elham Panahandeh,  Erfaneh Ghassami,  Milad Etemadi Sh,  Sarah Seyedyousefi,  Jaleh Varshosaz, 
  • First Published: 13 June 2025
Research Article
Open Access

Influence of Rifampicin on the Pharmacokinetics of the Glucokinase Activator Globalagliatin: A Single-Center, Open-Label, Fixed-Sequence Investigation in Healthy Chinese Volunteers

Yaqin Wang,  Ya Liu,  Maodi Xu,  Minhui Wang,  Xiaohu Wang,  Weijin Liu,  Cuilian Jiang,  Lin Tan,  Suoshuan Liu,  Hua Sun,  Haitang Xie, 
  • First Published: 30 May 2025
Research Article
Open Access

Impact of Area Under the Concentration–Time Curve–Based Vancomycin Dosing on Efficacy and Safety in Patients With Methicillin-Resistant Staphylococcus aureus Bacteremia

Amy T. Chang,  Christie Davis,  Megan Cheatham,  Kerri Degenkolb,  Christopher Geik,  Michael B. Kays,  Sharon M. Erdman, 
  • First Published: 28 May 2025
Research Article
Open Access

Polypharmacy and Potential Drug–Drug Interactions in Patients With Atrial Fibrillation

Ying Bai,  Jianqi Wang,  Guangyao Li,  Zhen Zhou, 
  • First Published: 18 May 2025
Research Article
Open Access

Wenjing Zhitong Decoction Alleviates Primary Dysmenorrhea Mediated by Pain Sensitization Via the ERα-BDNF Signaling Pathway

Yajie Qin,  Xiaotian Yang,  Xingran Tang,  Huijin Zhao,  Huifang Zhou, 
  • First Published: 14 May 2025
Research Article
Open Access

Linezolid-Induced Lactic Acidosis: Avoiding Concomitant Use With Metformin and Monitoring Linezolid Trough Concentration

Yao-Jie Chen,  Jing Fu,  Jun-Hui Yu,  Li-Wen Zhang,  Chuang Chen,  Hai-Na Zhang,  Xu-Ben Yu,  Guan-Yang Lin,  Xiu-Hua Zhang, 
  • First Published: 14 April 2025
Research Article
Open Access

Efficacy of Biological or Targeted Synthetic Disease-Modifying Anti-Rheumatic Drugs in Active Psoriatic Arthritis: A Network Meta-Analysis of Randomized Controlled Trials

Siming Gao,  Hui Song, 
  • First Published: 28 March 2025
Research Article
Open Access

Exploring the Therapeutic Effect of Quercetin in Asthma and Pulmonary Fibrosis Overlap Syndrome Post-COVID-19

Baolan Wang,  Zhe Zhang,  Yi Wang,  Rong Zhu,  Xiuqin Zhang, 
  • First Published: 27 March 2025
Research Article
Open Access

Pirfenidone Alleviates Intrauterine Infection-Induced Lung Injuries in Neonates by Targeting Transforming Growth Factor Beta 1/Sma- and Mad-Related Protein Signaling Pathway

Wenling Ding,  Renchang Liu,  Chunyou Wu,  Ruobing Shan, 
  • First Published: 26 March 2025
Research Article
Open Access

A Network Pharmacology-Based Strategy for Predicting Anti-Inflammatory Targets of Zao Ren An Shen Capsule in the Treatment of Asthma

Baolan Wang,  Zhe Zhang,  Yi Wang,  Rong Zhu,  Xiuqin Zhang, 
  • First Published: 26 March 2025
Research Article
Open Access

Exploring the Antibiofilm and Antibacterial Potential of Datura stramonium and Prosopis farcta Against Gram-Positive and Gram-Negative Bacteria

Soheila Shahroodian,  Maryam Mirshekar,  Maryam Koupaei,  Shiva Mirkalantari,  Nour Amirmozafari, 
  • First Published: 25 March 2025
Research Article
Open Access

Efficacy and Safety of Intranasal Dexmedetomidine Combined With Oral Chloral Hydrate for Sedation in Neonatal MRI Procedures: A Single-Center Retrospective Study

Wenyan Dong,  Lingdi Zhu,  Linlin Xu,  Zhenkun Yang,  Shuoxiong Wu, 
  • First Published: 24 March 2025
Research Article
Open Access

Impaired Autophagic Flux by Citalopram Inhibits DR5 Degradation and Increases TRAIL-Mediated Apoptosis

K. M. A. Zinnah,  Ali Newaz Munna,  Jae-Won Seol,  Sang-Youel Park, 
  • First Published: 20 March 2025
Research Article
Open Access

SGLT2 Inhibitors Increase Hemoglobin and Hematocrit Levels in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis

Hye Duck Choi,  Seung Woo Lee, 
  • First Published: 19 March 2025
Research Article
Open Access

Population Pharmacokinetics and AUC-Based Dose Optimization of Vancomycin in Chinese Neonates

Caiyan Yang,  Shifeng Wei,  Bo Wang,  Jiayu Yang,  Zhigang Zhao,  Daqing Xu,  Shenghui Mei, 
  • First Published: 12 March 2025
Review Article
Open Access

Proton Pump Inhibitor Use and Its Association With Asthma: A Systematic Review and Meta-Analysis

Ganesh Bushi,  Mahalaqua Nazli Khatib,  Suhas Ballal,  Pooja Bansal,  Balvir S. Tomar,  Ayash Ashraf,  M. Ravi Kumar,  Aashna Sinha,  Pramod Rawat,  Abhay M. Gaidhane,  Sanjit Sah,  Hashem Abu Serhan,  Mahendra Pratap Singh,  Muhammed Shabil, 
  • First Published: 11 March 2025
Research Article
Open Access

Determining the 90% Effective Dose of Remimazolam in Terms of Inhibiting Responses to Upper Gastrointestinal Endoscopy Insertion in Elderly Patients: A Double-Blind Study Utilizing a Biased Coin Up-and-Down Sequential Method

Chaoliang Zhang,  Pengfei Yin,  Lufang Zhang,  Binwei Hu,  Mi Wang,  Xianhui Kang,  Xian Zhao, 
  • First Published: 28 February 2025
Research Article
Open Access

Real-Practice Analysis of Potential Antibiotic Interactions in Patients Treated With Immune Checkpoint Inhibitors: An Observational Study From an Italian Referral Cancer Center

Alberto Russi,  Camilla Saran,  Giulia Zanchetta,  Giorgia Zorzetto,  Giovanna Crivellaro,  Marco Maruzzo,  Giulia Pasello,  Alessio Fabozzi,  Chiara De Toni,  Carola Cenzi,  Elena Berti,  Silvia Cognolato,  Francesca Pipitone,  Alberto Bortolami,  Alice Capogrosso Sansone,  Chiara Salvato,  Francesca Bano,  Ugo Moretti,  Paola De Ambrosis,  Giovanna Scroccaro,  Marina Coppola, 
  • First Published: 28 February 2025
Research Article
Open Access

Analysis of Predictors of Adverse Events and Mortality Risk Associated With IL-6 Inhibitors: A Pharmacovigilance Study Using the FDA Adverse Event Reporting System Database

Meilin Fang,  Jinglin Li,  Boyang Zhuang,  Weijie Liang,  Ling Wang,  Cunze Wang,  Wujin Chen,  Fangqing Cai,  Junshan Ruan,  Zhuiliang Huang,  Yishun Jin, 
  • First Published: 22 January 2025
Research Article
Open Access

Epigenetic Alterations in Renal Clear Cell Carcinoma: A Comprehensive Expression and Clinical Outcome Analysis

Dafei Weng,  Zhenqian Qin,  Xuefeng Yuan,  Xuping Jiang,  Hua Rui, 
  • First Published: 10 January 2025
Research Article
Open Access

Examination of the Association Between Bisphenol-Related Genes and Lung Cancer

Lin Chen,  Min Zhou,  Dingliang Lv,  Shuiwei Qiu, 
  • First Published: 09 January 2025
Research Article
Open Access

Integrative Analysis of PPAR and Immune Pathways in Hepatocellular Carcinoma: Constructing a Prognostic Risk Model Using TCGA Data

Jiao Li,  Yang Chen,  Lei Cao, 
  • First Published: 03 January 2025