By utilization of ion diffusion inside the hydrogel, a novel design is proposed to invasively monitoring flow velocity inside microfluidic chips via streaming potential effect without sensors contacting with the internal liquid. The electrodes shape like a tiny “flow velocity” probe, which can move around to mapping the flow distribution in a chip with the spatial resolution of 1 mm. More details are discussed in the article by Liu et al. on page 571—577.

The activity of Au-CeO₂ catalyst for the water gas shift reaction is susceptible to the aggregation size and electronic state of Au species while understanding the authentic role of the isolated Au atoms was limited. In this work, by in-situ Raman and in-situ DRIFTS, Au atoms were uncovered to be responsible for enhancing the reducibility of the CeO₂ matrix, which improved the H₂O activation ability of catalysts. More details are discussed in the article by Jia et al. on page 636—644.

A high-resolution and non-invasive flow monitoring method in microfluidic chips is realized based on the hydrogel-assisted electrokinetic phenomenon. By sealing one side of the microchannel with a piece of hydrogel film, streaming potential inside the channel can be detected by a free-moving electric probe at outer surface of the hydrogel due to ion diffusion in the hydrogel.

The reductive cross-coupling of diaryl ethers and chlorosilanes with the chelation help of an o-amide auxiliary has been achieved for the first time by iron-catalyzed strong electrophilic C(aryl)—O and Si—Cl bonds cleavage, providing an efficient protocol for the synthesis of a range of functionalized arylsilanes.

A straightforward electrochemical reduction of benzo[b]thiophene 1,1-dioxides with HFIP as the hydrogen donor has been reported in an undivided cell under metal-free conditions. Moreover, the tolerance of various functional groups and scaled-up experiments showed the practicability and potential applications of this methodology.

New terpyridine-based polyoxometalates were synthesized as dual-site catalyst by using one-pot strategy, and had good catalytic performance of sulfide oxidation.

A Ni-catalyzed regiodivergent acylzincation/cyclization cascade reaction of styrene derivatives with alkylzinc reagent and atmospheric CO gas is developed, providing a variety of highly substituted carbocyclic compounds with satisfying yields. The reaction features good functional group tolerance as well as broad substrate scope including both 1,2-disubstituted and terminal alkenes.

The total synthesis of majusculamide D (1) was achieved from commercially available materials. In addition, we synthesized eight analogues. Our preliminary SAR study indicated that the C2−C3 and hydroxyl group at C10 of majusculamide D were essential for the high bioactivity against Panc-1 cells and substitution at C42 and C40 with the opposite methyl groups was well tolerated.

We studied the impact of polymer matrix (polyurethane and poly(methyl acrylate-co-2- ethylhexyl acrylate), respectively) on polymer mechanochromism from ESIPT reactions.

Two bimetallic Cu/Ag-Sb clusters, [Cu₂Sb₁₄]⁴⁻ and [Ag₂Sb₁₄]⁴⁻, comprising intact Sb₇ units, were successfully synthesized and characterized. Quantum chemical calculations reveal that the rhombic Cu₂Sb₂ units within the [Cu₂Sb₁₄]⁴⁻ cluster exhibit σ-antiaromatic properties, and additional bonding analysis demonstrates that Cu∙∙∙Cu or Ag∙∙∙Ag interactions can be characterized as metallophilic interactions.

We developed a series of SMAs with benzo[4,5]thieno[2,3-b]quinoxaline or 1-methylindoline-2,3-dione as new electron-deficient units, namely QW1, QW2, QW3, and QW4. QW1-based device yields the best device performance due to the better molecular packing and aggregation behaviors induced by better molecular planarity and small π∙∙∙π stacking distances.

A metal-free asymmetric hydrogenation of phenanthridines was successfully accomplished by using a chiral monoene-derived borane as a catalyst. A variety of optically active dihydrophenanthridines were furnished in high yields with up to 93% ee. The bulky substituents at one phenyl group was required to enhance the difference between the two sides of the N-ring.

The contribution of the distinct Au sites for the water-gas shift reaction is ambiguous. Based on our investigation results, it is found that both the clustered Au atoms and the isolated Au atoms were active sites for the reaction. However, the sorption behavior of reactant molecules was different upon the two kinds of Au-CeO₂ interface. The clustered Au sites could promote the reaction cycles by boosting CO adsorption, while the isolated Au atoms enhanced the H₂O activation ability via increasing the reducibility of CeO₂.

The main idea described in this paper is Iron catalyzed reductive cross-coupling of diaryl ethers and chlorosilanes via strong electrophilic C(aryl)—O and Si—Cl bonds cleavage. More details are discussed in the article by Liu et al. on page 578—584.

5-Methylcytosine (5mC) is recognized as the most pivotal epigenetic modification in higher eukaryotes, characterized by its dynamic and reversible presence in genomic DNA. The pathways responsible for DNA demethylation are essential, as they have profound functional significance and play key roles in various biological processes. More details about the mechanisms and biological functions of DNA demethylation are discussed in the article by Yuan et al. on page 645—651.