Ratiometric sensing with different detection modes (i.e., On/Off mode, On/Constant mode) could provide varied analytical performances. Here, we demonstrated that the analytical feature of ratiometric electrochemical biosensor can be programmed by alternating the binding site of ferrocene to DNA duplex to achieve detections with different modes.

MUTAB-capped semiconductor QDs are highly luminescent yet cytotoxic. HSA adsorption decreases both the photoluminescence and the cytotoxicity.

In this Emerging Topic, we introduce recent advances involving scanning photoelectrochemical microscopy and highlight its potential roles in revealing interfacial electron transfer reactions in microbial hybrid photosynthesis.

Self-powered artificial cells were developed by encapsulating thylakoids, which continuously convert light energy into chemical energy to produce ATP molecules under illumination. The production of ATP supplies energy for the biological enzyme cascade reactions to promote the generation of NADPH. The self-powered artificial cells were demonstrated to generate ATP and NADPH inside GUVs.

This review summarized the recent advance in the applicability of G-quadruplexes (G4s) as antiviral targets, therapeutic agents and diagnostic tools for coronavirus disease 2019 (COVID-19). Meanwhile, some challenges and perspectives were also presented, looking forward to advancing the G4s for COVID-19 therapy and diagnosis.

In this review, three main strategies for achieving single-atom catalysts (SACs) with excellent intrinsic activity in the context of the oxygen reduction reaction (ORR) mechanism are involved including the modulation of coordination environments, the construction of intrinsic defects, and the introduction of dual active sites. And discussions to improve the loading and utilization of active sites are given. This timely review may provide inspiration and reference for the future research of developing advanced SACs for ORR.

The analytical performance of H⁺-selective solid-contact ion-selective electrodes (SCISEs) based on solid contact polyaniline doped with chloride (PANI(Cl)) and poly(3,4-ethylenedioxythiophene) doped with poly(styrene sulfonate) (PEDOT(PSS)) was characterized by a developed coulometric signal transduction method. The exceptional behavior of PANI(Cl) H⁺-SCISEs from coulometric response and impedance spectrum shows that the capacitance estimated from impedance spectrum at low frequency 10 mHz and coulometric signal of PANI(Cl) based SCISEs is influenced by the applied potentials, whereas PEDOT(PSS) solid contact is independent from the chosen applied potentials.

The rising stretchable electrochemical sensors integrated with cell culture, mechanical loading and electrochemical sensing provide a new approach to monitor mechanically evoked biochemical signals from deformed cells. In this review, we summarize recent advances in the fabrication and functionalization of stretchable sensors, and highlight their application in real-time monitoring of cell mechanotransduction.

In this review, we introduce the recent advances in electrochemical mass spectrometry (EC-MS) techniques and their applications in real-time analysis and mechanism studies of reactions in electrochemical sensors, organic electrochemistry, and electrocatalysis. We hope this summary will attract the interest of scientists in related areas, who can cooperate and jointly promote the development of this interdisciplinary area.

An octanuclear palladacycle with B(3)–H bond activations can be obtained through the reaction between methyldithiocarboxyl o-carborane and bis(acetonitrile)dichloropalladium. Three of its substitution reactions have been explored with Pd₈ core remaining unchanged.