Light-Harvesting Artificial Cells for the Generation of ATP and NADPH†
Ziwei Su
State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, Heilongjiang, 150001 China
‡These authors contributed equally to this work.
†Dedicated to Professor Erkang Wang on the Occasion of His 90th Birthday.
Search for more papers by this authorXiangxiang Zhang
State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, Heilongjiang, 150001 China
‡These authors contributed equally to this work.
†Dedicated to Professor Erkang Wang on the Occasion of His 90th Birthday.
Search for more papers by this authorWeichen Wang
State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, Heilongjiang, 150001 China
Search for more papers by this authorMingdong Dong
Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, DK-8000 Denmark
Search for more papers by this authorCorresponding Author
Xiaojun Han
State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, Heilongjiang, 150001 China
E-mail: [email protected]Search for more papers by this authorZiwei Su
State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, Heilongjiang, 150001 China
‡These authors contributed equally to this work.
†Dedicated to Professor Erkang Wang on the Occasion of His 90th Birthday.
Search for more papers by this authorXiangxiang Zhang
State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, Heilongjiang, 150001 China
‡These authors contributed equally to this work.
†Dedicated to Professor Erkang Wang on the Occasion of His 90th Birthday.
Search for more papers by this authorWeichen Wang
State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, Heilongjiang, 150001 China
Search for more papers by this authorMingdong Dong
Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, DK-8000 Denmark
Search for more papers by this authorCorresponding Author
Xiaojun Han
State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, Heilongjiang, 150001 China
E-mail: [email protected]Search for more papers by this authorComprehensive Summary
The bottom-up construction of self-powered artificial cells is significant to understand the energy supply and metabolism of nature cells. Here, we demonstrate an efficient manner to build thylakoid-containing artificial cells, which continuously convert light energy into chemical energy to supply adenosine 5’-triphosphate (ATP) under light illumination. The production of ATP supplies energy to promote the biological enzyme cascade reactions, where glucose is transformed into glucose 6-phosphate (G6P) under the catalysis of hexokinase (HK). G6P was further converted to gluconolactone 6-phosphate (PG) in the presence of 6-phosphate dehydrogenase (G6PDH), meanwhile NADP+ was converted to nicotinamide adenine dinucleotide phosphate (NADPH). The self-powered artificial cells were demonstrated to generate ATP and NADPH successively, which provided a way for building more complicated artificial cells.
Supporting Information
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