Volume 41, Issue 4 pp. 443-457
Chemistry Authors Up Close

Stretchable Electrochemical Sensors: From Electrode Fabrication to Cell Mechanotransduction Monitoring

Wen-Ting Fan

Wen-Ting Fan

College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei, 430072 China

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Wei-Hua Huang

Corresponding Author

Wei-Hua Huang

College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei, 430072 China

E-mail: [email protected]; [email protected]Search for more papers by this author
Yan-Ling Liu

Corresponding Author

Yan-Ling Liu

College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei, 430072 China

E-mail: [email protected]; [email protected]Search for more papers by this author
First published: 17 October 2022
Citations: 6

Dedicated to Professor Erkang Wang on the Occasion of His 90th Birthday.

Comprehensive Summary

Electrochemical sensing faces huge challenges in characterizing the transient release of biochemical molecules from deformed cells, due to the severely mechanical mismatch between rigid electrodes and soft cells. In recent years, the emergence of stretchable electrochemical sensors has made a breakthrough by complying with the deformation of living cells and simultaneous monitoring of mechanically evoked biochemical signals. This review first summarizes two fundamental strategies for the fabrication of stretchable electrodes from the points of structure and material. Next, recent progresses in construction of functionalized interface to improve the performance of stretchable electrochemical sensors are presented. Then, the application of stretchable electrochemical sensors in real-time monitoring of biomolecules released by mechanically sensitive cells is introduced. Finally, some perspectives and challenges of stretchable electrochemical sensors regarding cell detection are discussed.image

What is the favorite and original chemistry developed in your research group?

The design and construction of electrochemical sensing platform for real-time monitoring of life activities.

What is the most important personality for scientific research?

Innovative spirit, strong curiosity and persistence.

How do you supervise your students?

Encourage students to think much and eager to innovate.

What are your hobbies?

I like music and playing badminton.

Who influences you mostly in your life?

My family and collaborators.

Could you please give us some advices on improving Chinese Journal of Chemistry?

Focusing on the originality of the manuscript.

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