MedComm – Biomaterials and Applications is a biomedical materials journal publishing pioneer works in all aspects of the intersection of medicine and materials science. We're interested in the use and the biological effects of materials in medicine practice.

Our content spans materials science, biotechnology, nanotechnology, drug delivery, medicinal chemistry, medical technology, regenerative medicine, diagnostic, theranostics, and biomedical devices.

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Advanced Responsive Hydrogels for Diabetic Wound Healing: Design Principles, Controlled Drug Delivery, Therapeutic Strategies, and Application Prospects

  •  14 July 2025

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Advanced Responsive Hydrogels for Diabetic Wound Healing: Design Principles, Controlled Drug Delivery, Therapeutic Strategies, and Application Prospects Issue 3, 2025

This review highlights pathological features of diabetic wounds, and explores the design principles and therapeutic strategies of smart responsive hydrogels. Importantly, the review evaluates the challenges associated with these technologies and outlines future engineering directions to optimize their clinical adoption. This review aims to contribute to the rational design and practical clinical application of smart hydrogels for chronic wound care.

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Advances of Microneedles for Cancer Diagnosis and Therapy

  •  3 July 2025

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Advances of Microneedles for Cancer Diagnosis and Therapy Issue 3, 2025

Schematic diagram of microneedle for cancer diagnosis and treatment.

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  •  24 June 2025
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Emerging Trends in Injectable Stimuli‐Responsive Hydrogel Microspheres: Design Strategies and Therapeutic Innovations

  •  19 June 2025

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Emerging Trends in Injectable Stimuli-Responsive Hydrogel Microspheres: Design Strategies and Therapeutic Innovations Issue 2, 2025

Hydrogel microspheres (HMs) enhance the properties of traditional hydrogels, offering better injectability and functionality. Advanced fabrication techniques enable precise control over their size and properties. Stimuli-responsive HMs, which react to pH, ROS, and enzymes, allow targeted drug release and tissue repair. This review discusses their materials, fabrication, and applications, with insights into future clinical potential.

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Bioengineered Nanozymes for Orthopedic Degenerative Diseases: From Catalytic Mechanisms to Multimodal Therapy

  •  12 June 2025

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Bioengineered Nanozymes for Orthopedic Degenerative Diseases: From Catalytic Mechanisms to Multimodal Therapy Issue 2, 2025

IDD and OA is caused by various mechanisms, creating a vicious cycle that impairs disc function. Nanozymes and nano-enzyme delivery systems offer innovative therapies by targeting these underlying mechanisms, such as anti-inflammatory therapy, ECM repair, cellular dysfunction and antioxidant therapy, providing a promising approach to restoring tissue homeostasis, improving cellular function, and promoting regeneration.

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The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.

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Recent progress in 3D printing degradable polylactic acid‐based bone repair scaffold for the application of cancellous bone defect

  •  29 July 2022

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Recent progress in 3D printing degradable polylactic acid-based bone repair scaffold for the application of cancellous bone defect Issue 1, 2022

This paper reviews the application of 3D printing biodegradable polylactic acid based materials in cancellous bone repair. Starting from the structure of cancellous bone, and then summarizes the classification of polylactic acid mixed with different types of biodegradable materials to combination with the implementation of 3D printing technology

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Recent advances in smart‐responsive hydrogels for tissue repairing

  •  10 October 2022

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Recent advances in smart-responsive hydrogels for tissue repairing Issue 2, 2022

Smart-responsive hydrogels can sense the small changes in the surrounding microenvironment and enable precise and controllable release of functional molecules. Smart-responsive hydrogels with various response mechanisms have attracted extensive attention in the field of tissue repair. We believe that they can be applied in a wider range of fields including but not limited to tissue repair in the future.

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Biomedical applications and prospects of temperature‐orchestrated photothermal therapy

  •  7 December 2022

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Biomedical applications and prospects of temperature-orchestrated photothermal therapy Issue 2, 2022

Photothermal therapy can be used for the treatment of tumors, tissue defects, and anti-infection, depending on the effects at varying temperatures. In this review, we summarize the recent developments in the application of temperature-dependent photothermal biomaterials, including the temperature ranges of 40–42°C, 43–50°C, and over 50°C. Moreover, the challenges and perspectives of biomaterials in addressing temperature-orchestrated PTT were discussed.

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Recent progress in thermosensitive hydrogels and their applications in drug delivery area

  •  11 August 2023

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Recent progress in thermosensitive hydrogels and their applications in drug delivery area Issue 3, 2023

Review Paper highlighted the background of thermosensitive hydrogels, their properties, and their applications in transdermal, oral, ophthalmic, intravaginal, nasal, rectal, cancer therapy, and cell-loaded drug delivery systems as shown in the preview.

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Nanotechnology connecting copper metabolism and tumor therapy

  •  14 April 2023

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Nanotechnology connecting copper metabolism and tumor therapy Issue 2, 2023

Copper metabolism is emerging as a therapeutic strategy for cancer treatment, and nanotechnology is being used to connect copper and tumor therapy. Copper deficiency and excess accumulation can cause cell damage, and nanotechnology is being used to reduce side effects and enhance therapeutic effects.

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