We designed a nanohydroxyapatite hydrogel with adjustable modulus of elasticity and encapsulated with OGP. This hydrogel has large porosity and good mechanical strength, which can promote the proliferation and differentiation of BMSC cells in the long term to repair large bone defects.

Schematic illustration of research and application of multifunctional nanogels in biomedical fields.

In this review, we summarize the different biomaterials and their properties for cardiac tissue engineering. Then, we present their applications in cardiac tissue engineering. Moreover, we discuss the challenges, provide the future development and fusion innovation using emerging technologies in cardiac tissue engineering. We expect this review offers some insights into the application of biomaterials in cardiac tissue engineering.

This image summarizes pathogens and therapeutic interventions for pelvic inflammatory disease. We summarize the intrinsic properties of hydrogels and the application methods used in vagina and urinary tract infections.

Functional hydrogels hold significant promise in promoting skin wound healing. They effectively isolate external contaminants, reduce infection risks, maintain wound cleanliness, and aid in promoting cell regeneration and tissue repair, thereby accelerating the healing process. This review outlines the development and classification of wound dressings, focusing on the role of functional hydrogel wound dressings in promoting wound healing.

Tumor immunotherapy uses the body's immune system to fight tumors, with advanced delivery systems being essential for improving efficacy and safety. Metal-organic frameworks, known for their porous structures and stability, present a promising biomedicine solution. Their nanoscale variants facilitate high drug loading, controlled release, and multifunctional strategies for cancer treatment by modulating the tumor microenvironment and reactivating antitumor immunity.

This review represents recent advances in biomimetic nanosystems based on cell membranes for promoting cancer immunotherapy from aspects of their roles in particular stages of the “cancer immunity cycle,” which includes (1) promoting tumor cells to release TAAs through the ICD; (2) increasing APCs presentation; (3) regulating T cells, including enhancing activation and inhibiting exhaustion; 4) modulating the immunosuppressive TME.

Two calcium sulfate hemihydrate powders with different aspect ratios were prepared, and the short rod calcium sulfate powder as solid phase and 1 wt% chitosan solution as liquid phase was the best method to obtain calcium sulfate/chitosan composite bone cement, which had more appropriate setting time, higher compressive strength, slower degradation, and better biocompatibility, and it would have a great potential to be used in bone defect field.