Ti₃C₂T_x has shown remarkable photodynamic-photothermal dual effects against methicillin-resistant Staphylococcus aureus. Under two different light sources (460/808 nm wavelength), the reactive oxygen species production and temperature rise exhibit significant differences. These mechanisms refine strategies for targeted antimicrobial treatment using Ti₃C₂T_x two-dimensional nanomaterials.

The recent advances in strong and tough biofibers are summarized, including their materials, spinning methods, strengthening strategies, and various applications. Four natural materials and spinning techniques developed to prepare strong and tough biofibers are introduced. Strategies for enhancing the mechanical performance of biofibers are discussed in detail, along with a discussion of the applications of high-performance biofibers in biomedical engineering.

Transforming into ionic liquids improves the solubility of the active pharmaceutical ingredients. Azelaic acid-ILs were synthesized with Tris, which was miscible with water. Then a novel ILs-based hydrogel of azelaic acid was prepared to treat acne.

Stimuli-responsive biomaterials are used to construct scaffolds seeded with cardiomyocytes to promote cardiac tissue regeneration.

In this study, we developed an enzyme-free dual-target microbial detection method using an aptamer-based target recognition and loop amplification-mediated dual bacterial sensor, which ultimately achieved ultra-sensitive detection of Escherichia coli and Salmonella enteritidis with a wide linear range through the innovative use of an aptamer-based target recognition and single-stranded DNA-mediated loop amplification and fluorescence amplification processes.

Biofilm-related infections in cardiovascular system involve infective endocarditis, prosthetic heart valve endocarditis as well as cardiac device-associated infections. There are still challenges remaining in the treatment of biofilm-related infections in cardiovascular system. The strategies of degrading EPS in biofilm, applications of nanodrug delivery systems for biofilm-related infections, the strategy for targeting drug resistance genes through gene editing technology, the strategy for targeting quorum sensing in biofilm are the promising bioengineering approaches to treat cardiovascular infection. In addition, antibacterial modification and antibiotics releasing graft are also inspiring approaches to prevent infections for cardiovascular devices.

To optimize mesenchymal stem cell (MSC)-based treatment strategy, the active monomer aloe emodin (AE) of rhubarb from a clinically proven Traditional Chinese Medicine formulation for severe acute pancreatitis (SAP) was utilized to pretreat MSCs in combination with interferon gamma (IFN-γ) in a synergistic manner. Umbilical cord mesenchymal stem cells with class II transactivator gene silencing combined with AE and IFN-γ pretreatment effectively alleviated the progression of SAP in mice indicating promising prospects for SAP treatment.

An overview of the synthesis procedure of fluorescent poly (ethylene glycol) (PEG) benzimidazolium-tagged acridine carboxylic acid mixture (PEG-b-ACA) depicting its change in fluorescence emission from green to red and its antibacterial, antifungal, antiviral and anticancer efficacy.