The cover image is based on the Case Report Cancrum oris and hemiparesis in a young female patient—a case report by Zilefac Brian Ngokwe et al., https://doi.org/10.1002/ccr3.9111

Squamous metaplasia of the eccrine ducts.

Elamipretide mechanism of action: Restoration of physiologically normal energetics.

Hypertrophic scar on the cornea in patient with Hurler syndrome.

CT scan of the patients lungs showing active lupus pneumonitis.

Segment of a glomerulus with four capillary loops showing podocytes with complete foot processes effacement, swollen cytoplasm and condensed cytoplasmic filaments over the underlying basement membrane (arrows), consistent with a minimal change type lesion. Electron-dense deposits are not observed, and the glomerular basement membranes appear normal (uranyl acetate-lead citrate, original magnification ×7,200).

Immune-related adverse events such as myositis and sclerosing cholangitis are rare, but can occur with immune checkpoint inhibitors. The figure shows the co-occurrence of these conditions.

Sagittal US scans of the left (A) and right (B) kidneys at 21 weeks and 6 days of gestation showing bilateral hyperechogenic nondifferentiated kidneys of normal size.

Skin-colored papules at the front of the scalp and forehead.

Dynamic Contrast-enhanced MR Lymphangiography prior to treatment with trametinib. (A) Coronal T2 weighted image, with arrows indicating the subcutaneous edema and arrow heads indicating the pleural fluid. (B) Coronal T2 weighted MR image after intranodal contrast injection. The arrows indicate the dermal backflow of the lymphatic contrast. There is no contrast enhancement of the thoracic duct.

Macroscopic examination of the resected specimen reveals cystic lesion in the head of the pancreas. (Arrow: cyst wall).

Transthoracic echocardiography showing a ruptured sinus of Valsalva of the right coronary cusp leading to the Left to Right shunt.