Clinical Case Reports is an open access journal aiming to improve global health outcomes by conveying important best practice messages and sharing clinical knowledge with medical case reports, clinical images, and procedural videos.

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As part of Wiley’s Forward Series, this journal offers a streamlined, faster publication experience with a strong emphasis on integrity. Authors receive practical support to maximize the reach and discoverability of their work.

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The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.

Open access

Fecal microbiota transplantation for rheumatoid arthritis: A case report

  •  906-909
  •  23 December 2020

Graphical Abstract

Fecal microbiota transplantation for rheumatoid arthritis: A case report Issue 2, 2021

No previous case of using fecal microbiota transplantation (FMT) to treat rheumatoid arthritis (RA) has been reported. We report a case of a patient with refractory RA successfully treated with FMT indicating that FMT may have a good therapeutic effect on RA.

Open access

Iron deficiency without anemia – a clinical challenge

  •  1082-1086
  •  17 April 2018

Graphical Abstract

Iron deficiency without anemia – a clinical challenge Issue 6, 2018

One should always consider iron deficiency (without anemia) as the cause of persisting, unexplained unspecific, often severe, symptoms, regardless of the primary underlying disease. The symptoms of iron deficiency may arise from the metabolic systems where many proteins are iron containing. Long-standing iron deficiency may be challenging to treat.

Open access

Esophageal atresia and Beckwith–Wiedemann syndrome in one of the naturally conceived discordant newborn twins: first report

  •  399-401
  •  13 January 2018

Graphical Abstract

Esophageal atresia and Beckwith–Wiedemann syndrome in one of the naturally conceived discordant newborn twins: first report Issue 2, 2018

Recent studies report a high incidence of monozygotic twinning in Beckwith–Wiedemann syndrome. A phenotypical discordance in monozygotic twins is rare. Twinning and Beckwith–Wiedemann syndrome show higher incidence in children born after assisted reproductive techniques. We report on the first observation of esophageal atresia and Beckwith–Wiedemann syndrome in one of the naturally conceived discordant monozygotic twins.

Open access

Alveolar ridge augmentation using the shell technique with allogeneic and autogenous bone plates in a split‐mouth design—A retrospective case report from five patients

  •  947-959
  •  29 December 2021

Graphical Abstract

Alveolar ridge augmentation using the shell technique with allogeneic and autogenous bone plates in a split-mouth design—A retrospective case report from five patients Issue 2, 2021

Atrophic alveolar ridges of five patients were augmented with allografts and autografts on opposite sites, followed by dental implantation. Both augmentation materials led to equivalent bone gains. Allografts did not compromise the clinical outcome.

Open access

Iron deficiency anemia due to excessive green tea drinking

  •  1053-1056
  •  5 October 2016

Graphical Abstract

Iron deficiency anemia due to excessive green tea drinking Issue 11, 2016

Tea interferes with iron absorption and can lead to iron deficiency anemia when consumed in large quantities. The rechallenge effect of green tea on anemia in a middle-aged man emphasizes the potential causal role of this beverage. Lifestyle and dietary habits are important diagnostic considerations in diseases of this type.

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Open access

Suicidal cut‐throat wound during LSD intoxication

Graphical Abstract

Suicidal cut-throat wound during LSD intoxication Issue 11, 2021

Lysergic acid diethylamide (LSD) is a potent hallucinogenic drug affecting the mood and perception of an individual. Although LSD-induced self-inflicted cut-throat wounds and self-harm injuries are extremely rarely reported behaviors, some reports are coming out in recent days that may complicate the depiction of scenarios in forensic psychiatry settings.

Open access

49,XXXXY syndrome: A case study and a systematic review of clinical features among the Iranian population

Graphical Abstract

49,XXXXY syndrome: A case study and a systematic review of clinical features among the Iranian population Issue 9, 2022

There is no association between maternal age and Fraccaro syndrome. Along with classical clinical features of Fraccaro syndrome, our case further presented unusual sexual masturbation behavior. Fraccaro syndrome features in an undiagnosed male should be followed by karyotype analysis and a subsequent appropriate treatment for adequate growth and pubertal development.

Open access

Antimonium crudum in pediatric skin conditions: A classical homeopathic case series

Graphical Abstract

Antimonium crudum in pediatric skin conditions: A classical homeopathic case series Issue 2, 2021

Homeopathic Antimonium crudum may be useful in many pediatric skin conditions if prescribed on symptom similarity. It may especially be helpful in reducing the use of antibiotics and steroids in this age-group if proven to be effective through larger scientific studies.

Open access

Dexamethasone and diclofenac intramuscular mixture injection and risk of death: A case series study

Graphical Abstract

Dexamethasone and diclofenac intramuscular mixture injection and risk of death: A case series study Issue 4, 2021

Dexamethasone and diclofenac are commonly used medications for multiple anti inflammatory and analgesic purposes. Despite the multiple evidences on the synergistic anti inflammatory actions of them, there are no studies on the safety of mixing them in the same syringe for injection. Three patients have died due to cardiovascular events within 24 hours of receiving dexamethasone and diclofenac injection mixture, which we hypothesis that it could be the main reason for their death due to potential drug-drug interaction.

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