This study characterized the short-term transient response of cartilage T₂ to running-induced loading in young healthy female runners. Decreases in cartilage T₂ in femoral, tibial, and patellar cartilage post-run varied over time, and each tissue had unique layer- and region-specific transient responses. These results provide new information and highlight the role of transient analysis in the investigation of cartilage response to biomechanical loading and establish preliminary recommendations for future large-scale studies on the effects of running on knee cartilage.

A longitudinal study of cemented hemiarthroplasty was explored using 9-month-old Sprague–Dawley rats with 0, 2, 6, 12, 26 week end points. Loss of fixation, with a progressive increase in cement–bone gap volume was found in the epiphysis (0.162 mm³/week) of the proximal tibia, but did not progress appreciably in the metaphysis (0.007 mm³/week). Loss of fixation in the rat model mimiced patterns found in human arthroplasty where radiolucencies initiate at the periphery of the implant, under the tibial tray.