Perspective Articles

Research perspectives: The 2013 AAOS/ORS research symposium on Bone Quality and Fracture Prevention
Eve Donnelly, Joseph M. Lane and Adele L. Boskey

Improving outcomes for posterolateral knee injuries
Robert F. LaPrade, Chad J. Griffith, Benjamin R. Coobs, Andrew G. Geeslin, Steinar Johansen and Lars Engebretsen

Biology of anterior cruciate ligament injury and repair: Kappa delta ann doner vaughn award paper 2013
Martha Meaney Murray and Braden C. Fleming

microRNAs and cartilage
Gary Gibson and Hiroshi Asahara

An overview of underlying causes and animal models for the study of age-related degenerative disorders of the spine and synovial joints
Nam Vo, Laura J. Niedernhofer, Luigi Aurelio Nasto, Lloydine Jacobs, Paul D. Robbins, James Kang and Christopher H. Evans

Prognosis and predictors of ACL reconstructions using the MOON cohort: A model for comparative effectiveness studies
Kurt P. Spindler, Richard D. Parker, Jack T. Andrish, Christopher C. Kaeding, Rick W. Wright, Robert G. Marx, Eric C. McCarty, Annunziato Amendola, Warren R. Dunn, Laura J. Huston, Frank E. Harrell Jr. and MOON Group

Current insights on the regenerative potential of the periosteum: Molecular, cellular, and endogenous engineering approaches
Céline Colnot, Xinping Zhang and Melissa L. Knothe Tate

Grand challenge competition to predict in vivo knee loads
Benjamin J. Fregly, Thor F. Besier, David G. Lloyd, Scott L. Delp, Scott A. Banks, Marcus G. Pandy and Darryl D. D'Lima

PDGF in bone formation and regeneration: New insights into a novel mechanism involving
MSCs Arnold I. Caplan, Diego Correa

Optimizing the osteogenic potential of adult stem cells for skeletal regeneration
Jung Yul Lim, Alayna E. Loiselle, Jeong Soon Lee, Yue Zhang, Joshua D. Salvi, Henry J. Donahue

Post-traumatic osteoarthritis: Improved understanding and opportunities for early intervention
Donald D. Anderson, Susan Chubinskaya,Farshid Guilak, James A. Martin, Theodore R. Oegema, Steven A. Olson, Joseph A. Buckwalter

Don’t Hedge Your Bets: Hedgehog Signaling as a Central Mediator of Endochondral Bone Development and Cartilage Diseases
Jason S. Rockel and Benjamin A. Alman

Post‐traumatic Osteoarthritis: Improved Understanding and Opportunities for Early Intervention
Chubinskaya, Farshid Guilak, James A. Martin, Theodore R. Oegema, Steven A. Olson and Joseph A. Buckwalter

Nanobiomaterial applications in orthopedic
Elizabeth M. Christenson, Kristi S. Anseth, Jeroen J.J.P. van den Beucken, Casey K. Chan, Batur Ercan, John A. Jansen, Cato T. Laurencin, Wan-Ju Li, Ramalingam Murugan, Lakshmi S. Nair, Seeram Ramakrishna, Rocky S. Tuan, Thomas J. Webster and Antonios G. Mikos

From Streaming Potentials to Shear Stress: 25 Years of Bone Cell Mechanotransduction
Ryan C. Riddle and Henry J. Donahue

Optimizing the Osteogenic Potential of Adult Stem Cells for Skeletal Regeneration
Jung Yul Lim, Alayna E. Loiselle, Jeong Soon Lee, Yue Zhang, Joshua D. Salvi and Henry J. Donahue

Grand challenge competition to predict in vivo knee loads
Benjamin J. Fregly, Thor F. Besier, David G. Lloyd, Scott L. Delp, Scott A. Banks, Marcus G. Pandy and Darryl D. D'Lima