The purpose of our study is to investigate the active compounds, target genes, pathways, and mechanisms of rhubarb in the treatment of papillary thyroid carcinoma (PTC) using network pharmacology and bioinformatics approaches. Study offers insights into rhubarb's pharmacology and potential in PTC treatment.

Raman spectroscopy in combination with principal component analysis-linear discriminant analysis succeeded in tracking liver fibrosis progression, assessing drug efficacy, and providing several potential biomarkers, including cytochrome C. Raman imaging further provided quantitative and spatial distribution of collagen and cytochrome C in situ. This could yield significant molecular information for quantitatively linking pathological assessment and the mechanism of drug action.

It is not sufficient to evaluate cryoprotectants (CPAs) only based on red blood cell (RBC) recovery. Their protective effects need to be estimated further by considering the safety and effectiveness. The safety of CPAs is defined as the degree of damage to RBCs, while the effectiveness is demonstrated by the properties of thawed RBCs.

A total of 6975 physicians and myopic patients from 161 medical institutions in China were surveyed. High myopia prevalence was 11.3% (22.59% of which had pathological myopia). A total of 48.7% of physicians believed patients had misconceptions about high/pathological myopia. A total of 61.4% of outpatients lacked access to specialized staff for patient education. Patients' online ophthalmology information preferences varied, influenced by factors such as family background, medical history, and myopia cognition.

In this perspective, we provide a summary of previous studies focusing on the intersection of epigenetic modifications, diet metabolism, and aging in inflammatory bowel disease (IBD). We explore the connection between relevant alterations in epigenetic modifications associated with aging and diet metabolism with the inflammatory response and microbial homeostasis in IBD. Furthermore, we propose several potential therapeutic targets and strategies based on the pathogenesis of IBD (by Figdraw, https://www.figdraw.com).

Multiple preclinical experiments and clinical trials have shown that oncolytic viruses (OVs) exhibit good antitumor activity in treating gliomas. This article summarizes the crucial clinical progress of various OVs in the treatment of glioma, the challenges faced by OVs in the treatment of glioma, and looks forward to the future development prospects of OVs.