• Issue

    Acute Medicine & Surgery: Volume 12, Issue 1

    January/December 2025

Issue Information

Free Access

Issue Information

  • First Published: 03 January 2025

CASE REPORT

Open Access

A case of glyphosate poisoning with falsely elevated creatinine levels measured by dry chemistry methods

  • First Published: 01 August 2025
A case of glyphosate poisoning with falsely elevated creatinine levels measured by dry chemistry methods

We describe a case of glyphosate poisoning in which creatinine levels were determined to be elevated using dry chemistry. Because the assay uses ammonia to measure creatinine levels, the ammonia generated from the isopropylamine salt in the glyphosate herbicide solution interferes with the assay, resulting in falsely high creatinine levels.

Open Access

Fulminant myocarditis in immune-mediated thrombotic thrombocytopenic purpura: A case report

  • First Published: 16 July 2025

This report describes a case of iTTP complicated by fulminant myocarditis, successfully managed with multidisciplinary treatment, including PE, steroids, and extracorporeal circulation. Recognizing myocarditis as a possible complication in an iTTP case and providing appropriate supportive therapy may contribute to improved prognosis.

ORIGINAL ARTICLE

Open Access

JAPAN Registry of Self-harm and Suicide Attempts: Study protocol and profile in 2022–2023

  • First Published: 13 July 2025
JAPAN Registry of Self-harm and Suicide Attempts: Study protocol and profile in 2022–2023

The JAPAN Registry of Self-harm and Suicide Attempts (JA-RSA) is the first nationwide prospective registry in Japan of patients with self-harm or suicide attempts presenting to critical care medical centers. Here is the study protocol and initial profile of JA-RSA.

CASE REPORT

Open Access

Superior-lateral patella dislocation with rotation along its vertical axis

  • First Published: 11 July 2025
Superior-lateral patella dislocation with rotation along its vertical axis

A modified reduction technique is essential for successful alignment in superior-lateral patellar dislocations with vertical rotation. Flexion of the hip, knee extension, and targeted valgus–varus forces facilitate realignment and clear the lateral femoral condyle.

Open Access

Gastric anisakiasis suspected by point-of-care ultrasound finding in the emergency department

  • First Published: 11 July 2025
Gastric anisakiasis suspected by point-of-care ultrasound finding in the emergency department

Point-of-care-ultrasound revealed the thickened gastric wall, which enabled us to suspect gastric anisakiasis, prompting an emergent upper gastrointestinal endoscopy. An emergency upper gastrointestinal endoscopy revealed the presence of three Anisakis larvae penetrating the gastric mucosa.

ORIGINAL ARTICLE

Open Access

A predictive model of delayed pseudoaneurysm formation in paediatric patients with isolated blunt splenic injury using logistic regression analysis

  • First Published: 11 July 2025
A predictive model of delayed pseudoaneurysm formation in paediatric patients with isolated blunt splenic injury using logistic regression analysis

A predictive model of delayed pseudoaneurysm formation after non-operative management in paediatric patients with isolated blunt splenic injury was constructed, showing moderate discrimination and good calibration. Further improvement using different model creation methods, such as machine learning, may be necessary

CASE REPORT

Open Access

Preoperative interventional radiology in penetrating posterior abdominal trauma with bowel injury: A case report

  • First Published: 07 July 2025
Preoperative interventional radiology in penetrating posterior abdominal trauma with bowel injury: A case report

A 76-year-old man sustained a penetrating posterior abdominal injury from a pruning shear, damaging the descending colon and lumbar arteries. Preoperative IR effectively controlled bleeding, enabling safe and efficient surgery.

ORIGINAL ARTICLE

Open Access

Hydrogen inhalation therapy alone may not alleviate intestinal mucosal damage in NOMI without total-layer necrosis: An experimental swine model study

  • First Published: 04 July 2025
Hydrogen inhalation therapy alone may not alleviate intestinal mucosal damage in NOMI without total-layer necrosis: An experimental swine model study

To our knowledge, this study is the first to investigate the effects of hydrogen inhalation therapy in the swine model of NOMI. Our findings indicate that hydrogen inhalation therapy alone is insufficient treatment for NOMI.

CASE REPORT

Open Access

Bickerstaff brainstem encephalitis developed quickly after COVID-19 infection

  • First Published: 02 July 2025
Bickerstaff brainstem encephalitis developed quickly after COVID-19 infection

Both patients developed central nervous system (CNS) symptoms within a week of COVID-19 onset, indicating that BBE develops immediately after prior infection. This disease should be considered if CNS symptoms appear rapidly after COVID-19.

ORIGINAL ARTICLE

Open Access

Comparison of bathing-related adverse events, including drowning, between hot spring bathing and general bathing: A single-center retrospective study

  • First Published: 23 June 2025
Comparison of bathing-related adverse events, including drowning, between hot spring bathing and general bathing: A single-center retrospective study

A retrospective single-center study investigating the characteristics of bathing-related adverse events found that patients transported from hot springs had a higher frequency of drowning. This study may inform clinical practices and public health policies to reduce the incidence of bathing-related emergencies.

REVIEW ARTICLE

Open Access

Gut dysbiosis and its treatment in patients with critical illness

  • First Published: 03 June 2025
Gut dysbiosis and its treatment in patients with critical illness

After severe injury, such as trauma, operation, burn, infection, shock, and bleeding, systemic inflammation progresses in various organs simultaneously. The gut is considered to have an important role in promoting systemic inflammation through bacterial translocation, intestinal lymphatic mediators, gut immunity, etc.

ORIGINAL ARTICLE

Open Access

Effect of closed negative pressure wound therapy after laparotomy for gastrointestinal perforation: A single-center observational study

  • First Published: 03 June 2025
Effect of closed negative pressure wound therapy after laparotomy for gastrointestinal perforation: A single-center observational study

Laparotomy for gastrointestinal perforation is associated with a high risk of surgical site infection (SSI). The application of closed NPWT in patients undergoing laparotomy for gastrointestinal perforation was associated with a lower incidence of SSI compared with that of standard surgical dressing. Closed NPWT may be an option for the prevention of SSI after gastrointestinal perforation.

Open Access

Current state and challenges of multidisciplinary collaboration by fire defense headquarters in Japan: A nationwide cross-sectional survey

  • First Published: 28 May 2025
Current state and challenges of multidisciplinary collaboration by fire defense headquarters in Japan: A nationwide cross-sectional survey

Of the 529 participating fire defense headquarters, 445 (84.1%) collaborated with long-term care, welfare, and health organizations within the communities, despite facing various challenges. It is essential for fire defense headquarters and community organizations to continue fostering collaboration, addressing challenges, and adopting best practices.

Open Access

Performance of Universal TOR rule for out-of-hospital cardiac arrest in the Pan-Asian Resuscitation Outcomes Study

  • First Published: 22 May 2025
Performance of Universal TOR rule for out-of-hospital cardiac arrest in the Pan-Asian Resuscitation Outcomes Study

Asian countries have a rapidly aging population and as a result, the number of older individuals transported emergently following out-of-hospital cardiac arrest (OHCA) has increased in recent years. The purpose of this study was to evaluate the characteristics and outcomes of OHCA cases in Japan, Korea, Singapore, and Taiwan in relation to the Universal TOR rule.

CASE REPORT

Open Access

Rapidly progressive dementia due to superior sagittal sinus dural arteriovenous fistula: A case report

  • First Published: 21 May 2025
Rapidly progressive dementia due to superior sagittal sinus dural arteriovenous fistula: A case report

This case highlights the importance of considering dural arteriovenous fistula (dAVF) as a differential diagnosis in patients presenting with cognitive decline, particularly when accompanied by progressive neurological symptoms. Our report may help clinicians broaden their differential diagnoses when faced with similar clinical presentations.

Open Access

A case report: Efficacy of thoracic MRA for ischemic stroke due to acute aortic dissection

  • First Published: 19 May 2025
A case report: Efficacy of thoracic MRA for ischemic stroke due to acute aortic dissection

Thoracic MRA is useful for diagnosing acute aortic dissection in patients with stroke.

ORIGINAL ARTICLE

Open Access

Incidence and risk stratification of caller noncompliance with dispatcher instructions for cardiopulmonary resuscitation

  • First Published: 14 May 2025
Incidence and risk stratification of caller noncompliance with dispatcher instructions for cardiopulmonary resuscitation

A model assigning 1 point for each of the following: patient age of ≥65 years, a familial relationship between the caller and the patient, and cardiac arrest in the bathroom, and effectively stratified the probability of caller noncompliance with dispatcher cardiopulmonary resuscitation instructions.

ORIGINAL ARTICLE

Open Access

Outcomes of blunt trauma patients in police versus ground ambulance transport across US trauma centers

  • First Published: 08 May 2025
Outcomes of blunt trauma patients in police versus ground ambulance transport across US trauma centers

This study examined outcomes of adult patients with blunt trauma, comparing police and emergency medical services transport. Survival rates were similar for both modes of transport at each trauma center level. Police involvement should be encouraged in blunt injury transport.

ORIGINAL ARTICLE

Open Access

Hemostatic technique using cyanoacrylate for fingertip cut injury: A review of 21 cases

  • First Published: 29 April 2025
Hemostatic technique using cyanoacrylate for fingertip cut injury: A review of 21 cases

A woman in her 70s cut the tip of her right thumb with a slicer, resulting in skin loss. Despite compression, hemostasis was not achieved. A cyanoacrylate sealing method was performed to achieve hemostasis. Six days later, the Aron Alpha A® coating detached, and the wound was nearly completely epithelialized.

CASE REPORT

Open Access

Bronchiolitis obliterans due to toxic epidermal necrolysis with structural evaluation using computed tomography bronchography: A case report

  • First Published: 14 April 2025
Bronchiolitis obliterans due to toxic epidermal necrolysis with structural evaluation using computed tomography bronchography: A case report

Awareness of bronchiolitis obliterans development after the acute phase of toxic epidermal necrolysis is crucial. CT bronchography in bronchiolitis obliterans is superior to conventional CT in visualizing bronchial changes and may be a valuable tool for early detection and monitoring of bronchiolitis obliterans in toxic epidermal necrolysis.

ORIGINAL ARTICLE

Open Access

mRNA–miRNA integration analysis of T-cell exhaustion in sepsis from community-acquired pneumonia

  • First Published: 02 April 2025
mRNA–miRNA integration analysis of T-cell exhaustion in sepsis from community-acquired pneumonia

mRNA–miRNA integration analysis in community-acquired pneumonia-associated sepsis revealed immune dysregulation with T-cell exhaustion, highlighting the activation of PD-1/PD-L1 and suppression of Th1 pathways. These findings provide insights into sepsis pathogenesis and potential therapeutic targets.

Open Access

Association of blood carboxyhemoglobin levels with mortality and neurological outcomes in out-of-hospital cardiac arrest

  • First Published: 23 March 2025
Association of blood carboxyhemoglobin levels with mortality and neurological outcomes in out-of-hospital cardiac arrest

Kaplan–Meier curve for survival within 30 days between the COHb 0.0% group and the COHb ≥ 0.1% group. The p value obtained from the log-rank test was 0.002.

Open Access

Early lymphopenia as a predictor of COVID-19 outcomes: A multicenter cohort study

  • First Published: 21 March 2025
Early lymphopenia as a predictor of COVID-19 outcomes: A multicenter cohort study

Lymphopenia immediately after the onset of the disease was associated with poor outcomes in COVID-19 patients. Lymphocyte count trend after onset could reflect the disease progression.

ORIGINAL ARTICLE

Open Access

Efficacy of near-infrared spectroscopy in diagnosing skin and soft tissue infections: A single-center retrospective study

  • First Published: 13 March 2025
Efficacy of near-infrared spectroscopy in diagnosing skin and soft tissue infections: A single-center retrospective study

Near-infrared spectroscopy reflects tissue blood flow and may be possible to distinguish between cellulitis and necrotizing fasciitis.

Open Access

Medical validity and layperson interpretation of emergency visit recommendations by the GPT model: A cross-sectional study

  • First Published: 12 March 2025
Medical validity and layperson interpretation of emergency visit recommendations by the GPT model: A cross-sectional study

In this cross-sectional study, we assessed the medical plausibility of ChatGPT's outputs as evaluated by seven experts and the interpretation of these outputs by 157 laypersons. ChatGPT demonstrated high accuracy in advising regarding emergency visits when evaluated by experts, but laypersons frequently misinterpreted its recommendations.

Open Access

Association between neurological outcomes and prehospital time in patients with out-of-hospital cardiopulmonary arrest

  • First Published: 06 March 2025
Association between neurological outcomes and prehospital time in patients with out-of-hospital cardiopulmonary arrest

The GAM plot showed that the adjusted odds ratio of prehospital time for the good neurological outcome was decreased linearly according to time, and the threshold was approximately 30 min.

Open Access

Difficult-to-transport cases and neurological outcomes of out-of-hospital cardiac arrest: A population-based nationwide study in Japan

  • First Published: 03 March 2025
Difficult-to-transport cases and neurological outcomes of out-of-hospital cardiac arrest: A population-based nationwide study in Japan

A higher proportion of difficult-to-transport cases was associated with poorer neurological outcomes and longer transport times in patients with OHCA.

Open Access

Evaluation of aerosol generation and cooling effects of evaporative plus convective cooling in heat stroke treatment: A simulation study

  • First Published: 28 February 2025
Evaluation of aerosol generation and cooling effects of evaporative plus convective cooling in heat stroke treatment: A simulation study

Heat stroke treatment simulation was conducted using dolls resembling heat stroke patients, and a greater cooling effect was observed with a typical electric fan than with a handheld fan. Because no aerosol was generated from the body surface by evaporation, there was no risk of aerosol-related viral infection.

Open Access

Automated CT image prescription of the gallbladder using deep learning: Development, evaluation, and health promotion

  • First Published: 27 February 2025

Automated CT image prescription of the gallbladder using deep learning: Development, evaluation, and health promotion

The proposed system achieves state-of-the-art performance in the automatic detection and diagnosis of gallbladder conditions in patients requiring cholecystectomy, with robust accuracy and computational efficiency, such as (A) a patient with acute cholecystitis and gallstones and (B) a healthy participant.

LIST OF REVIEWERS

Open Access

AMS Reviewer Summary 2024

  • First Published: 24 February 2025

GUIDELINES

Open Access

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2024

Nobuaki Shime Taka-aki Nakada Tomoaki Yatabe Kazuma Yamakawa Yoshitaka Aoki Shigeaki Inoue Toshiaki Iba Hiroshi Ogura Yusuke Kawai Atsushi Kawaguchi Tatsuya Kawasaki Yutaka Kondo Masaaki Sakuraya Shunsuke Taito Kent Doi Hideki Hashimoto Yoshitaka Hara Tatsuma Fukuda Asako Matsushima Moritoki Egi Shigeki Kushimoto Takehiko Oami Kazuya Kikutani Yuki Kotani Gen Aikawa Makoto Aoki Masayuki Akatsuka Hideki Asai Toshikazu Abe Yu Amemiya Ryo Ishizawa Tadashi Ishihara Tadayoshi Ishimaru Yusuke Itosu Hiroyasu Inoue Hisashi Imahase Haruki Imura Naoya Iwasaki Noritaka Ushio Masatoshi Uchida Michiko Uchi Takeshi Umegaki Yutaka Umemura Akira Endo Marina Oi Akira Ouchi Itsuki Osawa Yoshiyasu Oshima Kohei Ota Takanori Ohno Yohei Okada Hiromu Okano Yoshihito Ogawa Masahiro Kashiura Daisuke Kasugai Ken-ichi Kano Ryo Kamidani Akira Kawauchi Sadatoshi Kawakami Daisuke Kawakami Yusuke Kawamura Kenji Kandori Yuki Kishihara Sho Kimura Kenji Kubo Tomoki Kuribara Hiroyuki Koami Shigeru Koba Takehito Sato Ren Sato Yusuke Sawada Haruka Shida Tadanaga Shimada Motohiro Shimizu Kazushige Shimizu Takuto Shiraishi Toru Shinkai Akihito Tampo Gaku Sugiura Kensuke Sugimoto Hiroshi Sugimoto Tomohiro Suhara Motohiro Sekino Kenji Sonota Mahoko Taito Nozomi Takahashi Jun Takeshita Chikashi Takeda Junko Tatsuno Aiko Tanaka Masanori Tani Atsushi Tanikawa Hao Chen Takumi Tsuchida Yusuke Tsutsumi Takefumi Tsunemitsu Ryo Deguchi Kenichi Tetsuhara Takero Terayama Yuki Togami Takaaki Totoki Yoshinori Tomoda Shunichiro Nakao Hiroki Nagasawa Yasuhisa Nakatani Nobuto Nakanishi Norihiro Nishioka Mitsuaki Nishikimi Satoko Noguchi Suguru Nonami Osamu Nomura Katsuhiko Hashimoto Junji Hatakeyama Yasutaka Hamai Mayu Hikone Ryo Hisamune Tomoya Hirose Ryota Fuke Ryo Fujii Naoki Fujie Jun Fujinaga Yoshihisa Fujinami Sho Fujiwara Hiraku Funakoshi Koichiro Homma Yuto Makino Hiroshi Matsuura Ayaka Matsuoka Tadashi Matsuoka Yosuke Matsumura Akito Mizuno Sohma Miyamoto Yukari Miyoshi Satoshi Murata Teppei Murata Hiromasa Yakushiji Shunsuke Yasuo Kohei Yamada Hiroyuki Yamada Ryo Yamamoto Ryohei Yamamoto Tetsuya Yumoto Yuji Yoshida Shodai Yoshihiro Satoshi Yoshimura Jumpei Yoshimura Hiroshi Yonekura Yuki Wakabayashi Takeshi Wada Shinichi Watanabe Atsuhiro Ijiri Kei Ugata Shuji Uda Ryuta Onodera Masaki Takahashi Satoshi Nakajima Junta Honda Tsuguhiro Matsumoto
  • First Published: 24 February 2025

CASE REPORT

Open Access

Ruptured abdominal aortic aneurysm managed using resuscitative endovascular balloon occlusion of the aorta with a two-stage approach

  • First Published: 21 February 2025
Ruptured abdominal aortic aneurysm managed using resuscitative endovascular balloon occlusion of the aorta with a two-stage approach

Brachial Zone 1 REBOA was initially employed for rAAA resuscitation. Conversion to zone 3 REBOA, partial REBOA, and sufficient blood transfusion mitigated the REBOA-related complications.

Open Access

Jesaconitine monitoring in a case of severe aconitum poisoning with torsade de pointes treated via extracorporeal membrane oxygenation

  • First Published: 20 February 2025
Jesaconitine monitoring in a case of severe aconitum poisoning with torsade de pointes treated via extracorporeal membrane oxygenation

A male in his 20s with suicidal aconite root ingestion developed refractory TdP, requiring ECMO. His arrhythmia resolved as jesaconitine levels decreased below 1 ng/mL. This case highlights the correlation between jesaconitine concentration and clinical symptoms, suggesting its potential use in guiding treatment for severe Aconitum poisoning.

CASE REPORT

Open Access

Traumatic internal carotid artery aneurysm distant from facial bone fractures treated with a flow diverter stent: A case report

  • First Published: 24 January 2025
Traumatic internal carotid artery aneurysm distant from facial bone fractures treated with a flow diverter stent: A case report

A 20-year-old woman with a traumatic internal carotid artery aneurysm, distant from facial fractures, was successfully treated with a flow diverter stent, resulting in aneurysm occlusion and improved neurological symptoms. Early screening for cerebrovascular injury is critical in severe head trauma cases.

ORIGINAL ARTICLE

Open Access

Factors influencing the delivery of automated external defibrillators by lay rescuers to the scene of out-of-hospital cardiac arrests in schools

  • First Published: 24 January 2025
Factors influencing the delivery of automated external defibrillators by lay rescuers to the scene of out-of-hospital cardiac arrests in schools

We investigated factors affecting whether lay rescuers bring AEDs to nontraumatic OHCAs in Japanese schools. From 2008 to 2021, overall AED delivery rates improved significantly, but incidents involving female students and those occurring during non-sport activities still show lower AED delivery rates. Further efforts are necessary to address these disparities.

Open Access

Impact of COVID-19 on resuscitation after hospital arrival for patients with out-of-hospital cardiac arrest: An interrupted time series analysis

  • First Published: 24 January 2025
Impact of COVID-19 on resuscitation after hospital arrival for patients with out-of-hospital cardiac arrest: An interrupted time series analysis

The COVID-19 pandemic had little impact on the duration of CPR after hospital arrival; however, there was a significant decrease in intubation for patients with OHCA after hospital arrival.

CASE REPORT

Open Access

Inadvertent insertion of dialysis catheter into subclavian artery treated with a covered stent: A case report

  • First Published: 16 January 2025
Inadvertent insertion of dialysis catheter into subclavian artery treated with a covered stent: A case report

This report describes a subclavian artery injury caused by inadvertent cannulation of a dialysis catheter, successfully treated with GORE VIABAHN stentgraft using pull-through technique. Covered stents offer an effective solution for major vessel injuries requiring immediate hemostasis, particularly when direct surgery is complicated by underlying medical or anatomical conditions.

Open Access

Warfarin overdose successfully treated using prophylactic vitamin K infusion without severe coagulopathy: A case report

  • First Published: 09 January 2025
Warfarin overdose successfully treated using prophylactic vitamin K infusion without severe coagulopathy: A case report

Prophylactic vitamin K2 infusion successfully managed a warfarin overdose in a non-warfarin-dependent patient, preventing severe coagulopathy and hemorrhage despite the high initial warfarin concentration. This case suggests that early VK administration may be effective in avoiding complications in similar overdose scenarios.

ORIGINAL ARTICLE

Open Access

Hypothermia-associated acute pancreatitis: A multicenter prospective observational study

  • First Published: 03 January 2025
Hypothermia-associated acute pancreatitis: A multicenter prospective observational study

This study comprised a post hoc analysis of data from a multicenter prospective observational study (ICE-CRASH study). The incidence of acute pancreatitis was 3.8% in patients with accidental hypothermia ≤32°C. Patients who developed pancreatitis appeared to have been influenced by alcohol consumption. No strong predictors of pancreatitis were identified.