Esophageal Cancer

28 July 2022
28 July 2022

Esophageal Cancer

Open Access

MAGE-C3 promotes cancer metastasis by inducing epithelial-mesenchymal transition and immunosuppression in esophageal squamous cell carcinoma

MAGE-C3 promotes cancer metastasis by inducing epithelial-mesenchymal transition and immunosuppression in esophageal squamous cell carcinoma

Our results identified that MAGE-C3 promotes tumor metastasis not only through the EMT but also by protecting tumors from immunosurveillance

Open Access

Improved esophageal squamous cell carcinoma screening effectiveness by risk-stratified endoscopic screening: evidence from high-risk areas in China

Improved esophageal squamous cell carcinoma screening effectiveness by risk-stratified endoscopic screening: evidence from high-risk areas in China

Universal endoscopy screening is recommended for all aged 40-69 years in high-risk areas of China to control esophageal squamous cell carcinoma (ESCC). This study estimated risk-stratified endoscopic (RSES) strategies based on a previously developed ESCC prediction model in a representative Chinese population from high-risk areas. RSES would be a feasible strategy to optimize the current universal endoscopic screening strategy in high-risk areas by increasing efficiency and decreasing screening costs.

Open Access

Involvement of long non-coding RNAs in the progression of esophageal cancer

Involvement of long non-coding RNAs in the progression of esophageal cancer

LncRNAs play complex and diverse roles in EC by mediating proliferation, cell cycle, apoptosis, invasion, migration, EMT, drug resistance, etc., and are closely related to EC clinicopathology and prognosis.