• Issue

    Journal of Veterinary Internal Medicine: Volume 39, Issue 4

    July/August 2025
Previous Issue
Export Citation(s)Download PDF(s)

ISSUE INFORMATION

Open Access

Issue Information

  • First Published: 25 May 2025

STANDARD ARTICLE

Small Animal Internal Medicine Neurology

Open Access

The Vertebrate Breed Ontology: Toward Effective Breed Data Standardization

Kathleen R. Mullen,  Imke Tammen,  Nicolas A. Matentzoglu,  Marius Mather,  James P. Balhoff,  Elizabeth Esdaile,  Gregoire Leroy,  Carissa A. Park,  Halie M. Rando,  Nadia T. Saklou,  Tracy L. Webb,  Nicole A. Vasilevsky,  Christopher J. Mungall,  Melissa A. Haendel,  Frank W. Nicholas,  Sabrina Toro, 
  • First Published: 25 May 2025

Equine Immunology

Open Access

Immunological Responses to Tetanus and Influenza Vaccination in Donkeys

Maciej Perzyna,  Jowita Grzędzicka,  Dominika Milczek-Haduch,  Izabela Dąbrowska,  Michał Trela,  Bartosz Pawliński,  Olga Witkowska-Piłaszewicz, 
  • First Published: 25 May 2025

Small Animal Internal Medicine Infectious Disease

Open Access

Ehrlichia, Hepatozoon, and Babesia Coinfection Patterns Among Owned Dogs in Central Thailand

Rungrote Osathanon,  Aeknarin Saechin,  Chalisa Mongkolphan,  Benjaporn Bhusri,  Siriporn Tangsudjai, 
  • First Published: 30 May 2025

Small Animal Internal Medicine Cardiology

Open Access

Influence of Signalment Variables on Body Weight-Normalized Echocardiographic Measurements of Heart Size in 56 169 Adult Unsedated Normal Pure-Bred Cats

Jens Häggström,  Åsa Ohlsson,  Torkel Falk,  Gerhard Wess,  Jana Friederich,  Ulrika Olsson,  Lennart Nilsfors,  Jan-Gerd Kresken,  Kjell Högström,  Niek Beijerink,  Mark Rishniw,  Anna Tidholm,  Ingrid Ljungvall, 
  • First Published: 30 May 2025

Small Animal Internal Medicine Gastroenterology

Open Access

Long-Term Follow-Up After Acute Gastroenteritis Caused by Giardia Infection in Juvenile Dogs

Karla C. Walz,  Jan S. Suchodolski,  Melanie Werner,  Felix Grimm,  Manuela Schnyder,  Yury Zablotski,  Stefan Unterer, 
  • First Published: 31 May 2025

Equine Gastroenterology

Open Access

Blood and Peritoneal Lactate, Ratio and Difference, and Peritoneal Lactate to Total Solids Ratio for Detection of Intestinal Strangulating Obstructions in Horses

Leonardo A. Parra-Moyano,  Alejandro Cedeño,  Shannon Darby,  Jessica P. Johnson,  Diego E. Gomez, 
  • First Published: 31 May 2025

Small Animal Internal Medicine Nephrology/Urology

Open Access

Apoptosis Inhibitor of Macrophages in Cats: A Potential Link Between an Exon 3 Variant Allele and Progression of Naturally Occurring Chronic Kidney Disease

Gabriela C. L. Evangelista,  Julianne K. Hwang,  Liam E. Broughton-Neiswanger,  Emily C. Carlo Reis,  Michael H. Court,  Katrina A. Mealey,  Nicolas F. Villarino, 
  • First Published: 31 May 2025

Small Animal Internal Medicine Cardiology

Open Access

Preoperative Prediction Models for 30-Day All-Cause Mortality After Mitral Valve Repair in Dogs: A Single-Center Retrospective Cohort Study

Shimon Furusato,  Kentaro Kurogochi,  Masashi Mizuno,  Satoru Shinoda,  Reo Tanoshima,  Masami Uechi, 
  • First Published: 01 June 2025

LETTER TO THE EDITOR

Open Access

Letter Regarding “Prognostic Potential of Copper, Zinc, Copper/Zinc Ratio, Cobalamin, and Serum Amyloid A in Cats With Panleukopenia”

Samuel J. Pearce, 
  • First Published: 01 June 2025
Open Access

Response to Letter Regarding “Prognostic Potential of Copper, Zinc, Copper/Zinc Ratio, Cobalamin, and Serum Amyloid A in Cats With Panleukopenia”

Kerim Emre Yanar,  Sümeyye Baysal,  Negis Ulaş,  Mustafa Sinan Aktaş,  Mehmet Özkan Timurkan,  Hakan Aydın, 
  • First Published: 01 June 2025

STANDARD ARTICLE

Food & Fiber Animal Respiratory

Open Access

Thoracic Ultrasonography Findings and Their Association With Respiratory Pathogens in 221 Young Beef Cattle at Fattening Farms: A Cross-Sectional Study

Maud Rouault,  Gilles Foucras,  François Meurens,  Sébastien Assié, 
  • First Published: 01 June 2025

Small Animal Internal Medicine Gastroenterology

Open Access

Comparison of Clinical, Laboratory, and Ultrasonographic Findings in Dogs With Acutely Presenting Clinical Signs and Either Normal or Increased Serum DGGR Lipase Activity

Melanie Sidler,  Daniel Brugger,  Barbara Riond,  Matthias Dennler,  Stefan Unterer,  Peter H. Kook, 
  • First Published: 01 June 2025

Food & Fiber Animal Cardiology

Open Access

Twenty-Four-Hour Electrocardiographic Monitoring for Assessment of Cardiac Arrhythmias in Healthy and Hospitalized Goats

Alyssa Sullivan,  Darcy B. Adin,  Sara B. Speziok,  Dana Haimovitz,  Todd C. Holbrook,  Daniela Luethy, 
  • First Published: 01 June 2025

Small Animal Internal Medicine Respiratory

Open Access

Exercise Restriction Does Not Change Outcome in Dogs After Diagnosis of Acute Non-Compressive Nucleus Pulposus Extrusion, Fibrocartilaginous Embolism, or Hydrated Nucleus Pulposus Extrusion

Katherine Phillips,  Paul Freeman, 
  • First Published: 03 June 2025

Small Animal Internal Medicine Cardiology

Open Access

Retrospective Evaluation of Transcatheter Edge-To-Edge Mitral Valve Repair in Dogs With Myxomatous Mitral Valve Disease

Jeong-Min Lee,  Kyoung-a Youp,  Sun-Tae Lee,  Ah-Ra Lee,  Young-Wook Cho,  Youn-Seo Jung,  Jiwoong Her,  Seung-Keun Lee, 
  • First Published: 03 June 2025

Small Animal Internal Medicine Nephrology/Urology

Open Access

Retrospective Evaluation of Risk Factors and Outcome in Dogs With and Without Fluid Overload During Hospitalization

Alexandra Pfaff,  Emmanuelle M. Butty,  Elizabeth A. Rozanski,  Armelle M. deLaforcade,  Jacqueline N. Hicks,  Noa Berlin, 
  • First Published: 03 June 2025

Small Animal Internal Medicine Genetics

Open Access

Identification of a Novel Mutation in the SERPINE1 Gene Causing Clinical Hyperfibrinolysis in English Springer Spaniel Dogs

Kelley Kilpatrick,  Jonah N. Cullen,  Farah F. Almeer,  LeeAnn Higgins,  Todd Markowski,  Marjory Brooks,  Steven G. Friedenberg,  Molly Racette, 
  • First Published: 05 June 2025

ERRATUM

Open Access

Erratum for “Prognostic Potential of Copper, Zinc, Copper/Zinc Ratio, Cobalamin, and Serum Amyloid A in Cats With Panleukopenia”

  • First Published: 06 June 2025

STANDARD ARTICLE

Small Animal Internal Medicine Neurology

Open Access

Brain Atrophy in Dogs With Meningoencephalitis of Unknown Origin

Rita Gonçalves,  Gemma Walmsley,  Thomas W. Maddox, 
  • First Published: 06 June 2025

Equine Endocrinology

Open Access

Markers of Hepatic Insulin Clearance and Their Association With Steatosis in Hyperinsulinaemic Horses

Miranda Dosi,  Laura Scott,  Holly Payne,  Jacqueline Poldy,  John Keen,  Bruce McGorum,  Alexandra Malbon,  Ruth Morgan, 
  • First Published: 06 June 2025

ERRATUM

Open Access

Erratum to “Fatty Acid Analysis and Stability of Selected Edible Oils Used in Homemade Pet Diets”

  • First Published: 06 June 2025

STANDARD ARTICLE

Small Animal Internal Medicine Gastroenterology

Open Access

Treatment of Hypovitaminosis D With Cholecalciferol in Dogs With Protein-Losing Enteropathies: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial

Sara A. Jablonski,  Sarah B. Shropshire,  Victoria E. Watson,  Alison C. Manchester,  Harry Cridge,  Elizabeth M. Lennon,  M. Katherine Tolbert, 
  • First Published: 08 June 2025

Small Animal Internal Medicine Immunology

Open Access

Prevalence of Proteinuria in Dogs With Immune-Mediated Disease

James C. Barton,  Alexander J. German,  Erin M. O'Connell, 
  • First Published: 08 June 2025

Food & Fiber Animal Gastroenterology

Open Access

Changes in Serum Proteomic Profiles at Different Stages of Pregnancy Toxemia in Goats

Murat Uztimür,  Cennet Nur Ünal,  Gürler Akpınar, 
  • First Published: 10 June 2025

CASE REPORT

Small Animal Internal Medicine Neurology

Open Access

Focal Autonomic Seizures Manifesting With Prevailing Signs of Gastrointestinal Disorder in Dogs

Solene Diop,  Elsa Lyon,  Nicolas Van Caenegem,  Catherine Escriou,  Valérie Freiche,  Stéphane Blot, 
  • First Published: 11 June 2025

Small Animal Internal Medicine Endocrinology

Open Access

Hypersomatotropism and Hypercortisolism Caused by a Plurihormonal Pituitary Adenoma in a Dog

Elber A. Soler Arias,  Ricardo Rodas Elvir,  Adrian F. Daly,  Hans S. Kooistra, 
  • First Published: 17 June 2025

STANDARD ARTICLE

Small Animal Internal Medicine Neurology

Open Access

Long-Term Clinical Response to Medical Treatment, Behavioral Therapy, or Their Combination in Cats With Hyperesthesia Syndrome

Claudia Pauciulo,  Stefania Uccheddu,  Andrea Corda,  Federica Biggio,  Daniele Sebastian Corlazzoli,  Marika Menchetti,  Antonella Gallucci, 
  • First Published: 17 June 2025

Equine Immunology

Open Access

Long-Term Humoral Immune Response After West Nile Virus Convalescence in Horses in a Geographic Area of Multiple Orthoflavivirus Co-Circulation

Csenge Hanna Tolnai,  Petra Forgách,  András Marosi,  Orsolya Fehér,  Bettina Paszerbovics,  Miklós Tenk,  Zsombor Wagenhoffer,  Orsolya Kutasi, 
  • First Published: 17 June 2025

Small Animal Internal Medicine Cardiology

Open Access

Long-Term Outcomes of Mitral Valve Repair With Artificial Chordae and Annuloplasty for Myxomatous Mitral Valve Disease in Dogs

Kentaro Kurogochi,  Shimon Furusato,  Emi Takahashi,  Miho Tabata,  Masashi Mizuno,  Yasuyuki Nii,  Masami Uechi, 
  • First Published: 17 June 2025

REVIEW

Small Animal Internal Medicine Immunology

Open Access

Immunosenescence and Inflammaging in Dogs and Cats: A Narrative Review

Brennen A. McKenzie, 
  • First Published: 31 May 2025

Small Animal Internal Medicine Neurology

Open Access

Comparison of Dysautonomia Across Species: Current Knowledge and Future Research Opportunities

Callum N. Atkins,  Caroline N. Hahn,  Bruce C. McGorum, 
  • First Published: 17 June 2025

CASE REPORT

Small Animal Internal Medicine Immunology

Open Access

Use of Immunosuppression, Romiplostim, and Splenectomy to Achieve Remission in a British Shorthair Cat With Primary Immune-Mediated Thrombocytopenia

Josh M. Kennils,  Helen E. Wilson, 
  • First Published: 17 June 2025

STANDARD ARTICLE

Small Animal Internal Medicine Endocrinology

Open Access

Frequency, Risk Factors, and Mortality for Diabetes Mellitus in 1 225 130 Cats Under Primary Veterinary Care in the United Kingdom in 2019

Oliver Waite,  Ruth Gostelow,  Emma Wright,  Rosanne E. Jepson,  Dave C. Brodbelt,  Dan G. O'Neill, 
  • First Published: 17 June 2025

Small Animal Internal Medicine Neurology

Open Access

Major Complications Associated With Cerebrospinal Fluid Collection in 11 Dogs: Clinical Presentation and Imaging Characteristics

Cecilia-Gabriella Danciu,  Alana McCarthy,  Abbe Crawford, 
  • First Published: 17 June 2025

Food & Fiber Animal Genetics

Open Access

Prevalence and Whole Genome Sequence Analysis of Mycoplasma bovis Isolates From Bulk Tank Milk of Dairy Farms in Tennessee, USA

Aga E. Gelgie,  Benti D. Gelalcha,  Daniel Christensen,  Trevor Freeman,  Jonathan E. Beever,  Oudessa Kerro Dego, 
  • First Published: 17 June 2025
Open Access

De Novo Missense Variant in Bovine WDR33 Associated With a Complex Syndromic Form of Cleft Palate With Pentalogy of Fallot and Internal Hydrocephalus

Marilena Bolcato,  Giovanni Romito,  Irene M. Häfliger,  Arcangelo Gentile,  Cord Drögemüller,  Joana G. P. Jacinto, 
  • First Published: 17 June 2025

ERRATUM

Open Access

Erratum for "Polypoid Cystitis: A Retrospective Case-Series of 112 Dogs”

  • First Published: 18 June 2025

Open Access

Erratum for “Association of Diet with Treatment Response in Dogs With Chronic Enteropathy: A Retrospective Multicenter Study”

  • First Published: 18 June 2025

STANDARD ARTICLE

Small Animal Internal Medicine Endocrinology

Open Access

Freestyle Libre-Derived Metrics in Assessing Glycemic Control in Diabetic Dogs

Francesca Del Baldo,  Antonio M. Tardo,  Chen Gilor,  Jocelyn Mott,  Caterina Da Vela,  Valeria Pergolese,  Federico Fracassi, 
  • First Published: 18 June 2025

CASE REPORT

Food & Fiber Animal Hematology

Open Access

Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case Report

Carla K. Enriquez,  Alicia E. Long,  Cristobal Navas de Solis,  Perry L. Habecker,  Rose Nolen-Walston, 
  • First Published: 23 June 2025

Small Animal Internal Medicine Respiratory

Open Access

Esophageal Candidiasis in Two Dogs With Megaesophagus: A Case Report

Katie L. Anderson,  Karen M. Tefft, 
  • First Published: 26 June 2025

STANDARD ARTICLE

Small Animal Internal Medicine Neurology

Open Access

Utility of a Modified Penlight-Cover Test for Neurolocalization of Lesions Based on Visual Suppression of Nystagmus in Dogs and Cats With Vestibular Disease

Alice Chan,  Gemma E. Longson,  Edward Ives,  Claire Turner,  Paul Freeman,  Stacey Brady,  Ana Martinez Loro,  Bruno Scalia,  Susana Monforte Monteiro,  Sara Formoso,  Sam Khan,  An E. Vanhaesebrouck, 
  • First Published: 27 June 2025

Small Animal Internal Medicine Gastroenterology

Open Access

Randomized Open-Label Clinical Trial Comparing Prednisolone and Cyclosporine With a Nonrandomized Active Control for Treating Presumed Chronic Pancreatitis in Cats

Yu-An Wu,  Jonathan A. Lidbury,  Samiran Sinha,  Jörg M. Steiner, 
  • First Published: 27 June 2025

Small Animal Internal Medicine Oncology

Open Access

Longitudinal Assessment of QT Apex in Tumor-Bearing Dogs Receiving Doxorubicin Monotherapy

Keita Kitagawa,  Jacob Ryave,  Robert A. Sanders,  Ji-Hyun Lee,  Zhongyue Zhang,  Paulo Vilar Saavedra, 
  • First Published: 26 June 2025

Small Animal Internal Medicine Neurology

Open Access

Case–Control Investigation of Association of Clinician-Determined Variables With Progressive Myelomalacia After Acute Thoracolumbar Disc Extrusion in Dogs

Eileen Donoghue,  Joe Mankin,  Nick Jeffery, 
  • First Published: 27 June 2025

Equine Cardiology

Open Access

Evaluation of Subjective Assessment of Right Heart Size and Function Using Standard 2D-Echocardiographic Recordings in Horses With and Without Pulmonary Hypertension

Julia N. van Spijk,  Hannah K. Junge,  Christina Eberhardt,  Natalie Wolf,  Debora Vogt,  Paula Zscherpe,  Elena Herger,  Manon Straub,  Colin C. Schwarzwald, 
  • First Published: 30 June 2025

Small Animal Internal Medicine Cardiology

Open Access

Myocardial and Renal Renin–Angiotensin System Enzyme Activity in Dogs

Emma C. Weitzhandler,  Marisa K. Ames,  Machelle D. Wilson,  Oliver Domenig, 
  • First Published: 02 July 2025

CASE REPORT

Small Animal Internal Medicine Hepatology

Open Access

Use of a Modified Transhepatic Rendezvous Technique for Stenting of Malignant Biliary Obstruction in 2 Cats

Robin Doherty,  Allyson C. Berent,  Chick Weisse, 
  • First Published: 04 July 2025

STANDARD ARTICLE

Small Animal Internal Medicine Nephrology/Urology

Open Access

Continuous Renal Replacement Therapy: Application of Kidney Disease Improving Global Outcomes Guidelines for Treatment Prescription in Dogs With Acute Kidney Injury and Outcome Prediction

Hilli Raskansky,  Yaron Bruchim,  Ran Nivy, 
  • First Published: 04 July 2025
Open Access

Metabolic Alterations Associated With Rapidly Progressive Chronic Kidney Disease in Cats

Laurens van Mulders,  Ellen vanden Broecke,  Femke Mortier,  Ellen de Paepe,  Lynn Vanhaecke,  Sylvie Daminet, 
  • First Published: 07 July 2025

Small Animal Internal Medicine Other

Open Access

Exploring the Importance of Repeated Health Screening in Healthy Older Dogs

Sofie Marynissen,  Femke Mortier,  Luc Duchateau,  Pascale Smets,  Sylvie Daminet,  Dominique Paepe, 
  • First Published: 07 July 2025

Small Animal Internal Medicine Pharmacology

Open Access

Safety, Efficacy and Doxorubicin Pharmacokinetics During Cannabidiol/Cannabidiolic Acid Rich Hemp Oil Use in Dogs With Lymphoma Undergoing CHOP Chemotherapy

Amandine Lejeune,  Sandra Bechtel,  Rowan Milner,  Lana Fagman,  Francisco A. Leal Yepes,  Joseph J. Wakshlag, 
  • First Published: 07 July 2025

CASE REPORT

Small Animal Internal Medicine Genetics

Open Access

A CNTNAP1 Missense Variant Associated With Laryngeal Paralysis and Polyneuropathy in Young Great Dane Dogs

G. Diane Shelton,  Missy C. Carpentier,  Y. Michael Kimura,  Ling T. Guo,  Katie M. Minor, 
  • First Published: 07 July 2025

STANDARD ARTICLE

Small Animal Internal Medicine Pharmacology

Open Access

An e-Reporting Tool for Facilitating Submission of Veterinary Adverse Drug Reaction Reports

Heather Davies,  Steven Smyth,  Gina Pinchbeck,  Munir Pirmohamed,  Roy Savory,  P. J. Noble,  David Killick, 
  • First Published: 12 July 2025

Food & Fiber Animal Pharmacology

Open Access

Pharmacokinetics of Orally Administered Phenazopyridine in Goats With Obstructive Urolithiasis

Sienna L. Mitman,  Danielle A. Mzyk,  Blanca E. Camacho,  R. McAlister Council-Troche,  Jennifer Davis,  Derek M. Foster,  Jennifer Halleran, 
  • First Published: 26 June 2025

Equine Cardiology

Open Access

Orthodromic Atrioventricular Reentry Bradycardia and Tachycardia Caused by an Accessory Pathway in Horses

Eva Buschmann,  Charlotte Easton-Jones,  Glenn Van Steenkiste,  Hans De Wilde,  Veronica Roberts,  Mary Durando,  Annelies Decloedt,  Celia Marr,  Gunther van Loon, 
  • First Published: 17 July 2025

Small Animal Internal Medicine Neurology

Open Access

Longitudinal Assessment and Cost–Benefit Analysis of Prophylactic Fenestration in Chondrodystrophic Dogs With Follow-Up Magnetic Resonance Imaging

Daniel Low,  Vasileios Vallios,  Tomas Basto,  Marios Charalambous, 
  • First Published: 18 July 2025

CASE REPORT

Small Animal Internal Medicine Pharmacology

Open Access

Adverse Drug–Drug Interaction Between Phenobarbital and Fluconazole in Two Dogs

Maria Jaramillo,  Alejandra Mondino,  Michael Court,  Melissa J. Lewis,  Natasha J. Olby,  Karen R. Muñana, 
  • First Published: 19 July 2025

STANDARD ARTICLE

Small Animal Internal Medicine Nephrology/Urology

Open Access

Clinical and Pathologic Characterization of Proteinuric Kidney Disease in Australian and New Zealand Dogs

Lucy Kopecny,  Joanna D. White, 
  • First Published: 21 July 2025

CASE REPORT

Small Animal Internal Medicine Neurology

Open Access

Neurolymphomatosis of T-Cell Origin in a Dog

Marie-Kerstin Müller,  Michaela Irmscher,  Nadja Goldbach,  Alexander F. H. Haake,  Olivia Kershaw,  Penelope A. Baloi, 
  • First Published: 24 July 2025

ERRATUM

Open Access

Erratum for “Long-Term Outcomes of Mitral Valve Repair With Artificial Chordae and Annuloplasty for Myxomatous Mitral Valve Disease in Dogs”

  • First Published: 24 July 2025

Open Access

Erratum for “Prevalence of a Novel Immunogenic Feline Erythrocyte Antigen (FEA 6) and Expression Patterns Between FEAs”

  • First Published: 24 July 2025

Open Access

Erratum for “Feline Blood Donation: Description and Adverse Reactions From 29 201 Donation Events Between 2019 and 2023”

  • First Published: 25 July 2025