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    2019
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Research Article
Open Access

Human Adipose-Derived Stem Cells Promote Seawater-Immersed Wound Healing by Activating Skin Stem Cells via the EGFR/MEK/ERK Pathway

Jiachao Xiong,  Boyao Ji,  Liujun Wang,  Yazhou Yan,  Zhixiao Liu,  Shuo Fang,  Minjuan Wu,  Yue Wang,  Jianxing Song, 
  • First Published: 31 December 2019
Review Article
Open Access

Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives

Deyun Chen,  Qian Hou,  Lingzhi Zhong,  Yali Zhao,  Meirong Li,  Xiaobing Fu, 
  • First Published: 31 December 2019
Research Article
Open Access

Activator Protein-1 Transcriptional Activity Drives Soluble Micrograft-Mediated Cell Migration and Promotes the Matrix Remodeling Machinery

Martina Balli,  Jonathan Sai-Hong Chui,  Paraskevi Athanasouli,  Willy Antoni Abreu de Oliveira,  Youssef El Laithy,  Maurilio Sampaolesi,  Frederic Lluis, 
  • First Published: 31 December 2019
Research Article
Open Access

The Effect of Blood-Derived Products on the Chondrogenic and Osteogenic Differentiation Potential of Adipose-Derived Mesenchymal Stem Cells Originated from Three Different Locations

Markus Neubauer,  Olga Kuten,  Christoph Stotter,  Karina Kramer,  Andrea De Luna,  Thomas Muellner,  Zsombor Lacza,  Stefan Nehrer, 
  • First Published: 31 December 2019
Research Article
Open Access

Melatonin Reverses the Loss of Stemness Induced by TNF-α in Human Bone Marrow Mesenchymal Stem Cells through Upregulation of YAP Expression

Xudong Wang,  Tongzhou Liang,  Jincheng Qiu,  Xianjian Qiu,  Bo Gao,  Wenjie Gao,  Chengjie Lian,  Taiqiu Chen,  Yuanxin Zhu,  Anjing Liang,  Peiqiang Su,  Yan Peng,  Dongsheng Huang, 
  • First Published: 30 December 2019

Review Article
Open Access

Bone Tissue Regeneration in the Oral and Maxillofacial Region: A Review on the Application of Stem Cells and New Strategies to Improve Vascularization

Vivian Wu,  Marco N. Helder,  Nathalie Bravenboer,  Christiaan M. ten Bruggenkate,  Jianfeng Jin,  Jenneke Klein-Nulend,  Engelbert A. J. M. Schulten, 
  • First Published: 30 December 2019
Research Article
Open Access

GLP-1 Gene-Modified Human Umbilical Cord Mesenchymal Stem Cell Line Improves Blood Glucose Level in Type 2 Diabetic Mice

Ying Chang,  Mingxin Dong,  Yan Wang,  Haotian Yu,  Chengbiao Sun,  Xin Jiang,  Wei Chen,  Xin Wang,  Na Xu,  Wensen Liu,  Ningyi Jin, 
  • First Published: 27 December 2019
Review Article
Open Access

Therapeutic Potential of Mesenchymal Stem Cells and Their Secretome in the Treatment of Glaucoma

C. Randall Harrell,  Crissy Fellabaum,  Aleksandar Arsenijevic,  Bojana Simovic Markovic,  Valentin Djonov,  Vladislav Volarevic, 
  • First Published: 27 December 2019
Research Article
Open Access

Interleukin-1β Enhances Umbilical Cord Mesenchymal Stem Cell Adhesion Ability on Human Umbilical Vein Endothelial Cells via LFA-1/ICAM-1 Interaction

Tsai-Yi Wu,  Ya-Han Liang,  Jiahn-Chun Wu,  Hwai-Shi Wang, 
  • First Published: 27 December 2019
Review Article
Open Access

Bone Marrow-Derived Cell Therapies to Heal Long-Bone Nonunions: A Systematic Review and Meta-Analysis—Which Is the Best Available Treatment?

Silvia Palombella,  Silvia Lopa,  Silvia Gianola,  Luigi Zagra,  Matteo Moretti,  Arianna B. Lovati, 
  • First Published: 27 December 2019
Review Article
Open Access

Regulation and Directing Stem Cell Fate by Tissue Engineering Functional Microenvironments: Scaffold Physical and Chemical Cues

Fei Xing,  Lang Li,  Changchun Zhou,  Cheng Long,  Lina Wu,  Haoyuan Lei,  Qingquan Kong,  Yujiang Fan,  Zhou Xiang,  Xingdong Zhang, 
  • First Published: 27 December 2019
Research Article
Open Access

Human Adipose-Derived Hydrogel Characterization Based on In Vitro ASC Biocompatibility and Differentiation

Omair A. Mohiuddin,  Benjamen T. O’Donnell,  J. Nicholas Poche,  Rida Iftikhar,  Rachel M. Wise,  Jessica M. Motherwell,  Brett Campbell,  Suzana D. Savkovic,  Bruce A. Bunnell,  Daniel J. Hayes,  Jeffrey M. Gimble, 
  • First Published: 27 December 2019
Research Article
Open Access

Insulin Enhances the In Vitro Osteogenic Capacity of Flexor Tendon-Derived Progenitor Cells

Sushmitha S. Durgam,  Nadine N. Altmann,  Haley E. Coughlin,  Audrey Rollins,  Laura D. Hostnik, 
  • First Published: 27 December 2019
Research Article
Open Access

Efficient Differentiation of Mouse Induced Pluripotent Stem Cells into Alveolar Epithelium Type II with a BRD4 Inhibitor

Toru Momozane,  Eriko Fukui,  Soichiro Funaki,  Makoto Fujii,  Yuhei Kinehara,  Emiko Ito,  Shigeru Miyagawa,  Yuko Ohno,  Yoshiki Sawa,  Meinoshin Okumura,  Yasushi Shintani, 
  • First Published: 27 December 2019
Research Article
Open Access

Paracrine Proangiogenic Function of Human Bone Marrow-Derived Mesenchymal Stem Cells Is Not Affected by Chronic Kidney Disease

Femke C. C. van Rhijn-Brouwer,  Bas W. M. van Balkom,  Diana A. Papazova,  Diënty H. M. Hazenbrink,  Anke J. Meijer,  Isaac Brete,  Vidalmar Briceno,  Arjan D. van Zuilen,  Raechel J. Toorop,  Joost O. Fledderus,  Hendrik Gremmels,  Marianne C. Verhaar, 
  • First Published: 23 December 2019
Review Article
Open Access

Autologous Mesenchymal Stem Cell Transplantation in Multiple Sclerosis: A Meta-Analysis

Yang Zhou,  Xin Zhang,  Hang Xue,  Lingling Liu,  Jie Zhu,  Tao Jin, 
  • First Published: 23 December 2019
Editorial
Open Access

Tissue-Derived Stem Cell Research 2019

Ming Li,  Kequan Guo,  Luca Vanella, 
  • First Published: 19 December 2019
Research Article
Open Access

Vernolactone Promotes Apoptosis and Autophagy in Human Teratocarcinomal (NTERA-2) Cancer Stem-Like Cells

Nuwanka K. Abeysinghe,  Ira Thabrew,  Sameera R. Samarakoon,  Meran K. Ediriweera,  Kamani H. Tennekoon,  Varuni P. C. Pathiranage,  Anuka S. Mendis, 
  • First Published: 19 December 2019
Research Article
Open Access

Evaluation of Chitosan Hydrogel for Sustained Delivery of VEGF for Odontogenic Differentiation of Dental Pulp Stem Cells

Si Wu,  Yachuan Zhou,  Yi Yu,  Xin Zhou,  Wei Du,  Mian Wan,  Yi Fan,  Xuedong Zhou,  Xin Xu,  Liwei Zheng, 
  • First Published: 19 December 2019
Research Article
Open Access

In Vivo Magic Angle Magnetic Resonance Imaging for Cell Tracking in Equine Low-Field MRI

Carolin Horstmeier,  Annette B. Ahrberg,  Dagmar Berner,  Janina Burk,  Claudia Gittel,  Aline Hillmann,  Julia Offhaus,  Walter Brehm, 
  • First Published: 17 December 2019
Research Article
Open Access

Efficient One-Step Induction of Human Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSCs) Produces MSC-Derived Neurospheres (MSC-NS) with Unique Transcriptional Profile and Enhanced Neurogenic and Angiogenic Secretomes

Chunyang Peng,  Yajiao Li,  Li Lu,  Jianwen Zhu,  Huiyu Li,  Jingqiong Hu, 
  • First Published: 17 December 2019
Research Article
Open Access

The Human Amniotic Mesenchymal Stem Cells (hAMSCs) Improve the Implant Osseointegration and Bone Regeneration in Maxillary Sinus Floor Elevation in Rabbits

Lu Yin,  Zhi-xuan Zhou,  Ming Shen,  Ning Chen,  Fei Jiang,  Shou-Lin Wang, 
  • First Published: 11 December 2019
Research Article
Open Access

Islet1 and Brn3 Expression Pattern Study in Human Retina and hiPSC-Derived Retinal Organoid

Ziming Luo,  Chaochao Xu,  Kaijing Li,  Bikun Xian,  Yuchun Liu,  Kang Li,  Ying Liu,  Huifeng Rong,  Mingjun Tang,  Dongpeng Hu,  Sijing Yang,  Meifang Ye,  Xiufeng Zhong,  Jian Ge, 
  • First Published: 10 December 2019
Research Article
Open Access

Mesenchymal Stem Cell-Derived Extracellular Vesicles for Corneal Wound Repair

Hongyan Tao,  Xiaoniao Chen,  Hongmei Cao,  Lingyue Zheng,  Qian Li,  Kaiyue Zhang,  Zhibo Han,  Zhong-Chao Han,  Zhikun Guo,  Zongjin Li,  Liqiang Wang, 
  • First Published: 09 December 2019
Research Article
Open Access

Decellularized Human Stromal Lenticules Combine with Corneal Epithelial-Like Cells: A New Resource for Corneal Tissue Engineering

Shuai Qin,  Shuai Zheng,  Bing Qi,  Rui Guo,  Guanghui Hou, 
  • First Published: 07 December 2019
Editorial
Open Access

Improving the Therapeutic Ability of Mesenchymal Stem/Stromal Cells for the Treatment of Conditions Influenced by Immune Cells

Lindolfo da Silva Meirelles,  Marcela F. Bolontrade,  Melissa Medeiros Markoski,  Bruno Dallagiovanna,  Laura Alaniz, 
  • First Published: 06 December 2019
Research Article
Open Access

CD8+γδ T Cells Are More Frequent in CMV Seropositive Bone Marrow Grafts and Display Phenotype of an Adaptive Immune Response

Ahmed Gaballa,  Lucas C. M. Arruda,  Emelie Rådestad,  Michael Uhlin, 
  • First Published: 06 December 2019
Review Article
Open Access

Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases

Yun-xia Zhao,  Shao-rong Chen,  Ping-ping Su,  Feng-huang Huang,  Yan-chuan Shi,  Qi-yang Shi,  Shu Lin, 
  • First Published: 06 December 2019
Research Article
Open Access

Mesenchymal Stem Cells Attract Endothelial Progenitor Cells via a Positive Feedback Loop between CXCR2 and CXCR4

Yingyun Tan,  Linjing Shu,  Peng Xu,  Shi Bai, 
  • First Published: 05 December 2019
Review Article
Open Access

Amino Acid-Mediated Metabolism: A New Power to Influence Properties of Stem Cells

Jilan Liu,  Xianyun Qin,  Dongfeng Pan,  Bin Zhang,  Feng Jin, 
  • First Published: 05 December 2019
Research Article
Open Access

Autologous Microfragmented Adipose Tissue Reduces the Catabolic and Fibrosis Response in an In Vitro Model of Tendon Cell Inflammation

Marco Viganò,  Gaia Lugano,  Carlotta Perucca Orfei,  Alessandra Menon,  Enrico Ragni,  Alessandra Colombini,  Paola De Luca,  Pietro Randelli,  Laura de Girolamo, 
  • First Published: 05 December 2019
Research Article
Open Access

Effects of Ginsenoside Rg1 Regulating Wnt/β-Catenin Signaling on Neural Stem Cells to Delay Brain Senescence

Yue Xiang,  Shun-he Wang,  Lu Wang,  Zi-ling Wang,  Hui Yao,  Lin-bo Chen,  Ya-ping Wang, 
  • First Published: 04 December 2019
Research Article
Open Access

The Effect of Vascular Endothelial Growth Factor on Bone Marrow Mesenchymal Stem Cell Engraftment in Rat Fibrotic Liver upon Transplantation

Ke Yuan,  Chunyou Lai,  Lingling Wei,  Tianhang Feng,  Qinyan Yang,  Tianying Zhang,  Tao Lan,  Yutong Yao,  Guangming Xiang,  Xiaolun Huang, 
  • First Published: 04 December 2019
Research Article
Open Access

Increased Neuronal Differentiation Efficiency in High Cell Density-Derived Induced Pluripotent Stem Cells

Sumitra Srimasorn,  Matthias Kirsch,  Susanne Hallmeyer-Ellgner,  Dirk Lindemann,  Alexander Storch,  Andreas Hermann, 
  • First Published: 04 December 2019
Review Article
Open Access

The Emerging Role of GC-MSCs in the Gastric Cancer Microenvironment: From Tumor to Tumor Immunity

Zhaoji Pan,  Yiqing Tian,  Guoping Niu,  Chengsong Cao, 
  • First Published: 02 December 2019
Research Article
Open Access

Reactivation of Denervated Schwann Cells by Embryonic Spinal Cord Neurons to Promote Axon Regeneration and Remyelination

Xinyu Fang,  Chaofan Zhang,  Chongjing Zhang,  Yuanqing Cai,  Zibo Yu,  Zida Huang,  Wenbo Li,  Wenming Zhang, 
  • First Published: 02 December 2019
Clinical Study
Open Access

A Multicentre Study: The Use of Micrografts in the Reconstruction of Full-Thickness Posttraumatic Skin Defects of the Limbs—A Whole Innovative Concept in Regenerative Surgery

Michele Riccio,  Andrea Marchesini,  Nicola Zingaretti,  Sara Carella,  Letizia Senesi,  Maria Giuseppina Onesti,  Pier Camillo Parodi,  Diego Ribuffo,  Luca Vaienti,  Francesco De Francesco, 
  • First Published: 01 December 2019
Research Article
Open Access

Dual Inhibition of BMP and WNT Signals Promotes Pancreatic Differentiation from Human Pluripotent Stem Cells

Mengtian Tan,  Lai Jiang,  Yinglei Li,  Wei Jiang, 
  • First Published: 01 December 2019
Research Article
Open Access

Systemic Infusion of Expanded CD133+ Cells and Expanded CD133+ Cell-Derived EVs for the Treatment of Ischemic Cardiomyopathy in a Rat Model of AMI

Addeli B. B. Angulski,  Luiz Guilherme A. Capriglione,  Fabiane Barchiki,  Paulo Brofman,  Marco A. Stimamiglio,  Alexandra C. Senegaglia,  Alejandro Correa, 
  • First Published: 01 December 2019
Research Article
Open Access

Mesenchymal Stromal Cells from the Epidermis and Dermis of Psoriasis Patients: Morphology, Immunophenotype, Differentiation Patterns, and Regulation of T Cell Proliferation

M. E. Castro-Manrreza,  L. Bonifaz,  O. Castro-Escamilla,  A. Monroy-García,  A. Cortés-Morales,  E. Hernández-Estévez,  J. Hernández-Cristino,  H. Mayani,  J. J. Montesinos, 
  • First Published: 01 December 2019
Research Article
Open Access

Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cell Line

Graciela Ruiz,  Heriberto A. Valencia-González,  Delia Pérez-Montiel,  Felipe Muñoz,  Rodolfo Ocadiz-Delgado,  Jorge Fernández-Retana,  Carlos Pérez-Plasencia,  Osbaldo Reséndis-Antonio,  Patricio Gariglio,  Alejandro García-Carrancá, 
  • First Published: 01 December 2019
Research Article
Open Access

Palmitic Acid Methyl Ester Induces G2/M Arrest in Human Bone Marrow-Derived Mesenchymal Stem Cells via the p53/p21 Pathway

Jian-Hong Lin,  Pei-Ching Ting,  Wen-Sen Lee,  Hung-Wen Chiu,  Chun-An Chien,  Chin-Hung Liu,  Li-Yi Sun,  Kun-Ta Yang, 
  • First Published: 01 December 2019
Research Article
Open Access

Strategy for the Generation of Engineered Bone Constructs Based on Umbilical Cord Mesenchymal Stromal Cells Expanded with Human Platelet Lysate

Ingrid Silva-Cote,  Mónica Cruz-Barrera,  Mariana Cañas-Arboleda,  Luz Correa-Araujo,  Leidi Méndez,  Joanna Jagielska,  Bernardo Camacho,  Gustavo Salguero, 
  • First Published: 01 December 2019
Research Article
Open Access

Exploring the Most Promising Stem Cell Therapy in Liver Failure: A Systematic Review

Jeanne AdiwinataPawitan, 
  • First Published: 01 December 2019
Research Article
Open Access

Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal Transition

Nanquan Rao,  Xiaotong Wang,  Jing Xie,  Jingzhi Li,  Yue Zhai,  Xiaoxia Li,  Tengjiaozi Fang,  Yuanyuan Wang,  Yuming Zhao,  Lihong Ge, 
  • First Published: 01 December 2019
Research Article
Open Access

MicroRNA-28-5p Regulates Liver Cancer Stem Cell Expansion via IGF-1 Pathway

Qing Xia,  Tao Han,  Pinghua Yang,  Ruoyu Wang,  Hengyu Li,  Jin Zhang,  Xinfeng Zhou, 
  • First Published: 01 December 2019
Research Article
Open Access

Structural and Functional Characterization of Deceased Donor Stem Cells: A Viable Alternative to Living Donor Stem Cells

Prakash N. Rao,  Dayanand D. Deo,  Misty A. Marchioni,  Rouzbeh R. Taghizadeh,  Kyle Cetrulo,  Sharyn Sawczak,  Jacob Myrick, 
  • First Published: 25 November 2019
Research Article
Open Access

Pyridoxal-5 ′-Phosphate Promotes Immunomodulatory Function of Adipose-Derived Mesenchymal Stem Cells through Indoleamine 2,3-Dioxygenase-1 and TLR4/NF-κB Pathway

Cong Li,  Jinxian Huang,  Huasu Zhu,  Qing Shi,  Dong Li,  Xiuli Ju, 
  • First Published: 25 November 2019
Research Article
Open Access

Reconstruction of Bone Defect Combined with Massive Loss of Periosteum Using Injectable Human Mesenchymal Stem Cells in Biocompatible Ceramic Scaffolds in a Porcine Animal Model

Chun-Cheng Lin,  Shih-Chieh Lin,  Chao-Ching Chiang,  Ming-Chau Chang,  Oscar Kuang-Sheng Lee, 
  • First Published: 23 November 2019
Research Article
Open Access

Rock Inhibitor Y-27632 Enables Feeder-Free, Unlimited Expansion of Sus scrofa domesticus Swine Airway Stem Cells to Facilitate Respiratory Research

Tina P. Dale,  Emily Borg D’anastasi,  Mohammed Haris,  Nicholas R. Forsyth, 
  • First Published: 23 November 2019
Research Article
Open Access

Strontium Promotes the Proliferation and Osteogenic Differentiation of Human Placental Decidual Basalis- and Bone Marrow-Derived MSCs in a Dose-Dependent Manner

Yi-Zhou Huang,  Cheng-Guang Wu,  Hui-Qi Xie,  Zhao-Yang Li,  Antonietta Silini,  Ornella Parolini,  Yi Wu,  Li Deng,  Yong-Can Huang, 
  • First Published: 22 November 2019
Research Article
Open Access

Novel Cryopreservation Approach Providing Off-the-Shelf Availability of Human Multipotent Mesenchymal Stromal Cells for Clinical Applications

Olena Rogulska,  Olga Tykhvynska,  Olena Revenko,  Viktor Grischuk,  Svitlana Mazur,  Natalia Volkova,  Roman Vasyliev,  Alexander Petrenko,  Yuriy Petrenko, 
  • First Published: 22 November 2019
Research Article
Open Access

Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro

Bishao Sun,  Xing Luo,  Chengfei Yang,  Peilin Liu,  Yang Yang,  Xingyou Dong,  Zhenxing Yang,  Jie Xu,  Yuanyuan Zhang,  Longkun Li, 
  • First Published: 22 November 2019

Review Article
Open Access

Strategies to Enhance Mesenchymal Stem Cell-Based Therapies for Acute Respiratory Distress Syndrome

Jibin Han,  Yanmin Li,  Yuanyuan Li, 
  • First Published: 22 November 2019
Research Article
Open Access

PTPN21 Overexpression Promotes Osteogenic and Adipogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells but Inhibits the Immunosuppressive Function

Huafang Wang,  Xiaohang Ye,  Haowen Xiao,  Ni Zhu,  Cong Wei,  Xiang Sun,  Limengmeng Wang,  Binsheng Wang,  Xiaohong Yu,  Xiaoyu Lai,  Shan Fu,  He Huang, 
  • First Published: 21 November 2019
Research Article
Open Access

Colony Formation, Migratory, and Differentiation Characteristics of Multipotential Stromal Cells (MSCs) from “Clinically Accessible” Human Periosteum Compared to Donor-Matched Bone Marrow MSCs

Heather E. Owston,  Payal Ganguly,  Giuseppe Tronci,  Stephen J. Russell,  Peter V. Giannoudis,  Elena A. Jones, 
  • First Published: 21 November 2019
Research Article
Open Access

Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells

Nihal AlMuraikhi,  Nuha Almasoud,  Sarah Binhamdan,  Ghaydaa Younis,  Dalia Ali,  Muthurangan Manikandan,  Radhakrishnan Vishnubalaji,  Muhammad Atteya,  Abdulaziz Siyal,  Musaad Alfayez,  Abdullah Aldahmash,  Moustapha Kassem,  Nehad M. Alajez, 
  • First Published: 21 November 2019
Clinical Study
Open Access

Preenrichment with Adipose Tissue-Derived Stem Cells Improves Fat Graft Retention in Patients with Contour Deformities of the Face

Muhammad M. Bashir,  Muhammad Sohail,  Fridoon J. Ahmad,  Mahmood S. Choudhery, 
  • First Published: 20 November 2019
Review Article
Open Access

Therapeutic Potential of Human Amniotic Epithelial Cells on Injuries and Disorders in the Central Nervous System

Huiming Xu,  Jiaofei Zhang,  Kam Sze Tsang,  Hao Yang,  Wei-Qiang Gao, 
  • First Published: 20 November 2019
Research Article
Open Access

Comparison of Properties of Stem Cells Isolated from Adipose Tissue and Lipomas in Dogs

Takahiro Teshima,  Akito Matsuoka,  Maika Shiba,  Kazuho Dairaku,  Hirotaka Matsumoto,  Ryohei Suzuki,  Hidekazu Koyama, 
  • First Published: 20 November 2019
Research Article
Open Access

Organotypic Cocultures of Human Pluripotent Stem Cell Derived-Neurons with Mammalian Inner Ear Hair Cells and Cochlear Nucleus Slices

Tomoko Hyakumura,  Stuart McDougall,  Sue Finch,  Karina Needham,  Mirella Dottori,  Bryony A. Nayagam, 
  • First Published: 20 November 2019
Research Article
Open Access

Effects of Stromal Cell-Derived Factor-1α Secreted in Degenerative Intervertebral Disc on Activation and Recruitment of Nucleus Pulposus-Derived Stem Cells

Jinwei Ying,  Zhihua Han,  Shishen Pei,  Linghao Su,  Dike Ruan, 
  • First Published: 19 November 2019
Review Article
Open Access

Adipose Stem Cell-Based Clinical Strategy for Neural Regeneration: A Review of Current Opinion

Yu-hao Wang,  Yu-chen Guo,  Dian-ri Wang,  Ji-yuan Liu,  Jian Pan, 
  • First Published: 19 November 2019
Research Article
Open Access

Increased BMPR1A Expression Enhances the Adipogenic Differentiation of Mesenchymal Stem Cells in Patients with Ankylosing Spondylitis

Zhenhua Liu,  Peng Wang,  Shuizhong Cen,  Liangbin Gao,  Zhongyu Xie,  Xiaohua Wu,  Hongjun Su,  Yanfeng Wu,  Huiyong Shen, 
  • First Published: 18 November 2019
Research Article
Open Access

Reprogrammed Cells Display Distinct Proteomic Signatures Associated with Colony Morphology Variability

Yngvild Bjørlykke,  Anne M. Søviknes,  Laurence Hoareau,  Heidrun Vethe,  Andreas F. Mathisen,  Simona Chera,  Marc Vaudel,  Luiza M. Ghila,  Helge Ræder, 
  • First Published: 18 November 2019
Research Article
Open Access

Adipose-Derived Stem Cell Transplantation Attenuates Inflammation and Promotes Liver Regeneration after Ischemia-Reperfusion and Hemihepatectomy in Swine

Zhihui Jiao,  Yajun Ma,  Xiaoning Liu,  Yansong Ge,  Qianzhen Zhang,  Boyang Liu,  Hongbin Wang, 
  • First Published: 18 November 2019
Research Article
Open Access

Genomics Analysis of Metabolic Pathways of Human Stem Cell-Derived Microglia-Like Cells and the Integrated Cortical Spheroids

Julie Bejoy,  Xuegang Yuan,  Liqing Song,  Thien Hua,  Richard Jeske,  Sébastien Sart,  Qing-Xiang Amy Sang,  Yan Li, 
  • First Published: 18 November 2019
Research Article
Open Access

Shear Stress Promotes Arterial Endothelium-Oriented Differentiation of Mouse-Induced Pluripotent Stem Cells

Yan Huang,  Xiaofang Chen,  Jifei Che,  Qi Zhan,  Jing Ji,  Yubo Fan, 
  • First Published: 15 November 2019
Research Article
Open Access

Effects of Placenta-Derived Mesenchymal Stem Cells on the Particulate Matter-Induced Damages in Human Middle Ear Epithelial Cells

So Young Kim,  Seung Ha Oh,  Jun Ho Lee,  Myung-Whan Suh,  Moo Kyun Park, 
  • First Published: 14 November 2019
Clinical Study
Open Access

In Vivo MRI Tracking of Mesenchymal Stromal Cells Labeled with Ultrasmall Paramagnetic Iron Oxide Particles after Intramyocardial Transplantation in Patients with Chronic Ischemic Heart Disease

Anders Bruun Mathiasen,  Abbas Ali Qayyum,  Erik Jørgensen,  Steffen Helqvist,  Annette Ekblond,  Michael Ng,  Kishore Bhakoo,  Jens Kastrup, 
  • First Published: 14 November 2019
Research Article
Open Access

Intra-Bone Marrow Administration of Mesenchymal Stem/Stromal Cells Is a Promising Approach for Treating Osteoporosis

Hideki Agata,  Yoshinori Sumita,  Tatsuro Hidaka,  Mayumi Iwatake,  Hideaki Kagami,  Izumi Asahina, 
  • First Published: 12 November 2019
Review Article
Open Access

Cancer Stem Cells: Powerful Targets to Improve Current Anticancer Therapeutics

Rayana L. Bighetti-Trevisan,  Lucas O. Sousa,  Rogerio M. Castilho,  Luciana O. Almeida, 
  • First Published: 12 November 2019
Research Article
Open Access

Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering

Dake Hao,  Chuanchao He,  Bowen Ma,  Lee Lankford,  Lizette Reynaga,  Diana L. Farmer,  Fuzheng Guo,  Aijun Wang, 
  • First Published: 12 November 2019
Research Article
Open Access

Improved Isolation of Mesenchymal Stem Cells Based on Interactions between N-Acetylglucosamine-Bearing Polymers and Cell-Surface Vimentin

Hirohiko Ise,  Kumiko Matsunaga,  Marie Shinohara,  Yasuyuki Sakai, 
  • First Published: 11 November 2019
Research Article
Open Access

A Three-Dimensional Culture Model of Reversibly Quiescent Myogenic Cells

Salvatore Aguanno,  Claudia Petrelli,  Sara Di Siena,  Luciana De Angelis,  Manuela Pellegrini,  Fabio Naro, 
  • First Published: 11 November 2019
Research Article
Open Access

CTGF Attenuates Tendon-Derived Stem/Progenitor Cell Aging

Yun-feng Rui,  Min-hao Chen,  Ying-juan Li,  Long-fei Xiao,  Peng Geng,  Pei Wang,  Zheng-yuan Xu,  Xuan-pu Zhang,  Guang-chun Dai, 
  • First Published: 11 November 2019
Research Article
Open Access

miRNAs in Extracellular Vesicles from iPS-Derived Cardiac Progenitor Cells Effectively Reduce Fibrosis and Promote Angiogenesis in Infarcted Heart

Wanling Xuan,  Lei Wang,  Meifeng Xu,  Neal L. Weintraub,  Muhammad Ashraf, 
  • First Published: 11 November 2019
Research Article
Open Access

Prx1-Expressing Progenitor Primary Cilia Mediate Bone Formation in response to Mechanical Loading in Mice

Emily R. Moore,  Julia C. Chen,  Christopher R. Jacobs, 
  • First Published: 11 November 2019
Research Article
Open Access

Serum-Free Culture of Human Mesenchymal Stem Cell Aggregates in Suspension Bioreactors for Tissue Engineering Applications

Leah M. Allen,  John Matyas,  Mark Ungrin,  David A. Hart,  Arindom Sen, 
  • First Published: 07 November 2019
Editorial
Open Access

Stem Cell Derived Organoids in Human Disease and Development

Stefan Liebau,  Holger A. Russ,  Alexander Kleger, 
  • First Published: 07 November 2019
Research Article
Open Access

Mesenchymal Stem Cells Alleviate Moderate-to-Severe Psoriasis by Reducing the Production of Type I Interferon (IFN-I) by Plasmacytoid Dendritic Cells (pDCs)

Maosheng Chen,  Jing Peng,  Qi Xie,  Na Xiao,  Xian Su,  Hua Mei,  Yeping Lu,  Jia Zhou,  Yanni Dai,  Siqi Wang,  Chuang Li,  Ge Lin,  Lamei Cheng, 
  • First Published: 07 November 2019
Research Article
Open Access

Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker

Yannan Hu,  Ning Li,  Liang Liu,  Hao Zhang,  Xiang Xue,  Xin Shao,  Yu Zhang,  Xilong Lang, 
  • First Published: 07 November 2019
Research Article
Open Access

The Manufacture of GMP-Grade Bone Marrow Stromal Cells with Validated In Vivo Bone-Forming Potential in an Orthopedic Clinical Center in Brazil

Rhayra B. Dias,  João A. M. Guimarães,  Marco B. Cury,  Leonardo R. Rocha,  Elaine S. da Costa,  Liebert P. Nogueira,  Camila Hochman-Mendez,  Anneliese Fortuna-Costa,  Anna Karoline F. Silva,  Karin S. Cunha,  Sergio A. L. de Souza,  Maria Eugênia L. Duarte,  Rafaela C. Sartore,  Danielle C. Bonfim, 
  • First Published: 07 November 2019
Research Article
Open Access

Is There a Noninvasive Source of MSCs Isolated with GMP Methods with Better Osteogenic Potential?

Carla C. G. Pinheiro,  Alessander Leyendecker Junior,  Daniela Y. S. Tanikawa,  José Ricardo Muniz Ferreira,  Reza Jarrahy,  Daniela F. Bueno, 
  • First Published: 06 November 2019
Review Article
Open Access

Adipose-Derived Stem Cells in Bone Tissue Engineering: Useful Tools with New Applications

Gabriele Storti,  Maria Giovanna Scioli,  Bong-Sung Kim,  Augusto Orlandi,  Valerio Cervelli, 
  • First Published: 06 November 2019
Research Article
Open Access

Stepwise Adipogenesis of Decellularized Cellular Extracellular Matrix Regulates Adipose Tissue-Derived Stem Cell Migration and Differentiation

Ziang Zhang,  Rongmei Qu,  Tingyu Fan,  Jun Ouyang,  Feng Lu,  Jingxing Dai, 
  • First Published: 06 November 2019
Research Article
Open Access

Adipose-Derived Mesenchymal Stem Cells Promote M2 Macrophage Phenotype through Exosomes

June Seok Heo,  Youjeong Choi,  Hyun Ok Kim, 
  • First Published: 05 November 2019
Research Article
Open Access

Complementary Embryonic and Adult Cell Populations Enhance Myocardial Repair in Rat Myocardial Injury Model

Sergio Li Calzi,  Todd Cook,  Domenico G. Della Rocca,  Juan Zhang,  Vinayak Shenoy,  Yuanqing Yan,  Andrew Espejo,  Anandharajan Rathinasabapathy,  Max H. Jacobsen,  Tatiana Salazar,  George E. Sandusky,  Lynn C. Shaw,  Keith March,  Mohan K. Raizada,  Carl J. Pepine,  Michael J. Katovich,  Maria B. Grant, 
  • First Published: 03 November 2019
Research Article
Open Access

Human Umbilical Cord-Derived Mesenchymal Stem Cell Therapy Ameliorates Nonalcoholic Fatty Liver Disease in Obese Type 2 Diabetic Mice

Bing Li,  Yu Cheng,  Songyan Yu,  Li Zang,  Yaqi Yin,  Jiejie Liu,  Lin Zhang,  Yiming Mu, 
  • First Published: 03 November 2019
Research Article
Open Access

Platelet-Rich Plasma Improves the Wound Healing Potential of Mesenchymal Stem Cells through Paracrine and Metabolism Alterations

Barbara Hersant,  Mounia Sid-Ahmed,  Laura Braud,  Maud Jourdan,  Yasmine Baba-Amer,  Jean-Paul Meningaud,  Anne-Marie Rodriguez, 
  • First Published: 31 October 2019
Research Article
Open Access

The DNMT1/miR-34a Axis Is Involved in the Stemness of Human Osteosarcoma Cells and Derived Stem-Like Cells

Xiao Liang,  Chang Xu,  Wanchun Wang,  Xiang Li, 
  • First Published: 31 October 2019
Research Article
Open Access

FoxO1 Overexpression Ameliorates TNF-α-Induced Oxidative Damage and Promotes Osteogenesis of Human Periodontal Ligament Stem Cells via Antioxidant Defense Activation

Xiaojun Huang,  Huan Chen,  Yunyi Xie,  Zeyuan Cao,  Xuefeng Lin,  Yan Wang, 
  • First Published: 31 October 2019
Research Article
Open Access

Synergistic Effects of Human Platelet-Rich Plasma Combined with Adipose-Derived Stem Cells on Healing in a Mouse Pressure Injury Model

Zhiyuan Liu,  Shune Xiao,  Kerong Tao,  Hai Li,  Wenhu Jin,  Zairong Wei,  Dali Wang,  Chengliang Deng, 
  • First Published: 30 October 2019
Research Article
Open Access

MicroRNA-150 Modulates Adipogenic Differentiation of Adipose-Derived Stem Cells by Targeting Notch3

Xiang Li,  Yu Zhao,  Xiuquan Li,  Qiao Wang,  Qiang Ao,  Xiaohong Wang,  Xiaohong Tian,  Hao Tong,  Deyu Kong,  Shijie Chang,  Shuling Bai,  Jun Fan, 
  • First Published: 30 October 2019
Research Article
Open Access

Isolation and Characterization of Neural Stem Cells from the Rat Inferior Colliculus

Johannes Völker,  Jonas Engert,  Christine Völker,  Linda Bieniussa,  Philipp Schendzielorz,  Rudolf Hagen,  Kristen Rak, 
  • First Published: 29 October 2019
Research Article
Open Access

Broad-Spectrum Antibacterial Effects of Human Adipose-Derived Stromal Cells

Paul Monsarrat,  Philippe Kémoun,  Louis Casteilla,  Valérie Planat-Bénard, 
  • First Published: 29 October 2019
Review Article
Open Access

Autologous Stem Cell Transplantation in Multiple Myeloma with Renal Failure: Friend or Foe?

Hongfei Zhong,  Xiaojie Xie,  Gaosi Xu, 
  • First Published: 29 October 2019
Research Article
Open Access

rBMSC/Cav-1F92A Mediates Oxidative Stress in PAH Rat by Regulating SelW/14-3-3η and CA1/Kininogen Signal Transduction

Wan-cheng Yu,  Hai-ying Chen,  Hong-li Yang,  Peng Xia,  Cheng-wei Zou,  Tong-wen Sun,  Le-xin Wang, 
  • First Published: 28 October 2019
Review Article
Open Access

Insights into the Effects of the Dental Stem Cell Secretome on Nerve Regeneration: Towards Cell-Free Treatment

Rohaina Che Man,  Nadiah Sulaiman,  Ruszymah Bt Hj Idrus,  Shahrul Hisham Zainal Ariffin,  Rohaya Megat Abdul Wahab,  Muhammad Dain Yazid, 
  • First Published: 24 October 2019
Research Article
Open Access

Depth-Dependent Cellular Response from Dental Bulk-Fill Resins in Human Dental Pulp Stem Cells

Su-Min Lee,  Soo-Youn Kim,  Jae-Heon Kim,  Soo-Kyung Jun,  Hae-Won Kim,  Jung-Hwan Lee,  Hae-Hyoung Lee, 
  • First Published: 24 October 2019
Research Article
Open Access

Microvesicles Derived from Human Embryonic Neural Stem Cells Inhibit the Apoptosis of HL-1 Cardiomyocytes by Promoting Autophagy and Regulating AKT and mTOR via Transporting HSP-70

Lei Zhang,  Jianyi Gao,  Tianyan Chen,  Xiang Chen,  Xianyan Ji,  Kai Ye,  Jiahong Yu,  Bin Tang,  Yusheng Wei,  Hong Xu,  Jiabo Hu, 
  • First Published: 24 October 2019
Research Article
Open Access

Combining ECM Hydrogels of Cardiac Bioactivity with Stem Cells of High Cardiomyogenic Potential for Myocardial Repair

Rui Bai,  Lei Tian,  Yi Li,  Jiao Zhang,  Yujie Wei,  Zhigeng Jin,  Zhiqiang Liu,  Huiliang Liu, 
  • First Published: 23 October 2019
Research Article
Open Access

Adipose-Derived Stem Cells Are an Efficient Treatment for Fistula-in-ano of Japanese Rabbit

Xiao Qin,  Peng Wang,  Yongming Huang,  Yansen Li,  Min Chao,  Wei Wang, 
  • First Published: 22 October 2019
Research Article
Open Access

miR-129-5p Regulates the Immunomodulatory Functions of Adipose-Derived Stem Cells via Targeting Stat1 Signaling

He-Yang Zhang,  Yu-Han Wang,  Yan Wang,  Yan-Nv Qu,  Xiao-Hui Huang,  Hui-Xin Yang,  Chang-Ming Zhao,  Youdi He,  Si-Wei Li,  Jin Zhou,  Changyong Wang,  Xiao-Xia Jiang, 
  • First Published: 21 October 2019
Research Article
Open Access

Adipose-Derived Mesenchymal Stem Cells Enhance Ovarian Cancer Growth and Metastasis by Increasing Thymosin Beta 4X-Linked Expression

Yijing Chu,  Min You,  Jingjing Zhang,  Guoqiang Gao,  Rendong Han,  Wenqiang Luo,  Tingting Liu,  Jianxin Zuo,  Fuling Wang, 
  • First Published: 20 October 2019
Research Article
Open Access

Static Magnetic Field Induced Neural Stem/Progenitor Cell Early Differentiation and Promotes Maturation

Shih-Yin Ho,  I-Chun Chen,  Yi-Jyun Chen,  Chien-Hsing Lee,  Chao-Ming Fu,  Fei-Chih Liu,  Horng-Huei Liou, 
  • First Published: 16 October 2019
Research Article
Open Access

Serum-Free Culture System for Spontaneous Human Mesenchymal Stem Cell Spheroid Formation

Guoyi Dong,  Shengpeng Wang,  Yuping Ge,  Qiuting Deng,  Qi Cao,  Quanlei Wang,  Zhouchun Shang,  Wenjie OuYang,  Jing Li,  Chao Liu,  Jie Tang,  Weihua Zhao,  Ying Gu, 
  • First Published: 15 October 2019
Research Article
Open Access

Human Umbilical Cord Mesenchymal Stem Cells Attenuate Ocular Hypertension-Induced Retinal Neuroinflammation via Toll-Like Receptor 4 Pathway

Shangli Ji,  Jie Xiao,  Jian Liu,  Shibo Tang, 
  • First Published: 15 October 2019
Research Article
Open Access

Injectable Hydrogel Combined with Nucleus Pulposus-Derived Mesenchymal Stem Cells for the Treatment of Degenerative Intervertebral Disc in Rats

Feng Wang,  Li-ping Nan,  Shi-feng Zhou,  Yang Liu,  Ze-yu Wang,  Jing-cheng Wang,  Xin-min Feng,  Liang Zhang, 
  • First Published: 15 October 2019
Review Article
Open Access

Tendon Stem/Progenitor Cells and Their Interactions with Extracellular Matrix and Mechanical Loading

Chuanxin Zhang,  Jun Zhu,  Yiqin Zhou,  Bhavani P. Thampatty,  James H-C. Wang, 
  • First Published: 13 October 2019
Review Article
Open Access

The Effects of Hypoxia on the Immune-Modulatory Properties of Bone Marrow-Derived Mesenchymal Stromal Cells

Zsolt Fábián, 
  • First Published: 08 October 2019
Research Article
Open Access

Optically Transparent Anionic Nanofibrillar Cellulose Is Cytocompatible with Human Adipose Tissue-Derived Stem Cells and Allows Simple Imaging in 3D

Jonathan J. Sheard,  Mesude Bicer,  Yiming Meng,  Alessia Frigo,  Rocío Martínez Aguilar,  Thomas M. Vallance,  Donata Iandolo,  Darius Widera, 
  • First Published: 07 October 2019
Research Article
Open Access

Healing of Bone Defects in Pig’s Femur Using Mesenchymal Cells Originated from the Sinus Membrane with Different Scaffolds

Rita Bou Assaf,  Kazem Zibara,  Mohammad Fayyad-Kazan,  Fatima Al-Nemer,  Manal Cordahi,  Saad Khairallah,  Bassam Badran,  Antoine Berbéri, 
  • First Published: 30 September 2019
Research Article
Open Access

Mitochondrial Fusion by M1 Promotes Embryoid Body Cardiac Differentiation of Human Pluripotent Stem Cells

Jarmon G. Lees,  Anne M. Kong,  Yi C. Chen,  Priyadharshini Sivakumaran,  Damián Hernández,  Alice Pébay,  Alexandra J. Harvey,  David K. Gardner,  Shiang Y. Lim, 
  • First Published: 19 September 2019
Erratum
Open Access

Erratum to “CFTR Expression Analysis for Subtyping of Human Pancreatic Cancer Organoids”

Alexander Hennig,  Laura Wolf,  Beatrix Jahnke,  Heike Polster,  Therese Seidlitz,  Kristin Werner,  Daniela E. Aust,  Jochen Hampe,  Marius Distler,  Jürgen Weitz,  Daniel E. Stange,  Thilo Welsch, 
  • First Published: 18 September 2019

Research Article
Open Access

Synergistic Improvement in Children with Cerebral Palsy Who Underwent Double-Course Human Wharton’s Jelly Stem Cell Transplantation

Xiaojun Fu,  Rongrong Hua,  Xiaodong Wang,  Peishen Wang,  Long Yi,  Aixue Yu,  Jing Yang,  Yan Li,  Yihua An, 
  • First Published: 17 September 2019
Review Article
Open Access

Molecular Profiles of Cell-to-Cell Variation in the Regenerative Potential of Mesenchymal Stromal Cells

Kim C. O’Connor, 
  • First Published: 17 September 2019
Research Article
Open Access

The Effect of Adipose-Derived Stem Cells on Wound Healing: Comparison of Methods of Application

Hyeonwoo Kim,  Mi Ri Hyun,  Sang Wha Kim, 
  • First Published: 17 September 2019

Research Article
Open Access

Protection of the Peritoneal Membrane by Peritoneal Dialysis Effluent-Derived Mesenchymal Stromal Cells in a Rat Model of Chronic Peritoneal Dialysis

Lan Zhou,  Ming Zong,  Qiunong Guan,  Gerald da Roza,  Hao Wang,  Hualin Qi,  Caigan Du, 
  • First Published: 16 September 2019
Review Article
Open Access

Dental Follicle Cells: Roles in Development and Beyond

Tao Zhou,  Jinhai Pan,  Peiyao Wu,  Ruijie Huang,  Wei Du,  Yachuan Zhou,  Mian Wan,  Yi Fan,  Xin Xu,  Xuedong Zhou,  Liwei Zheng,  Xin Zhou, 
  • First Published: 15 September 2019
Research Article
Open Access

A Retrospective Study on the Use of Dermis Micrografts in Platelet-Rich Fibrin for the Resurfacing of Massive and Chronic Full-Thickness Burns

Alessandro Andreone,  Daan den Hollander, 
  • First Published: 15 September 2019
Research Article
Open Access

Mesenchymal Stem Cells Alleviate DHEA-Induced Polycystic Ovary Syndrome (PCOS) by Inhibiting Inflammation in Mice

Qi Xie,  XingLiang Xiong,  Na Xiao,  Ke He,  Maosheng Chen,  Jing Peng,  Xian Su,  Hua Mei,  Yanni Dai,  Dan Wei,  Ge Lin,  Lamei Cheng, 
  • First Published: 12 September 2019
Review Article
Open Access

Glutamine Metabolism Is Essential for Stemness of Bone Marrow Mesenchymal Stem Cells and Bone Homeostasis

Tao Zhou,  Yuqing Yang,  Qianming Chen,  Liang Xie, 
  • First Published: 12 September 2019
Research Article
Open Access

Comparison of Rapidly Proliferating, Multipotent Aortic Valve-Derived Stromal Cells and Valve Interstitial Cells in the Human Aortic Valve

Yuming Huang,  Kang Xu,  Tingwen Zhou,  Peng Zhu,  Nianguo Dong,  Jiawei Shi, 
  • First Published: 10 September 2019
Research Article
Open Access

Pretreatment with AM1241 Enhances the Analgesic Effect of Intrathecally Administrated Mesenchymal Stem Cells

Junran Xie,  Jinxuan Ren,  Na Liu,  Chengwei Wu,  Dongju Xiao,  Huanyu Luo,  Jingxian Du, 
  • First Published: 10 September 2019
Review Article
Open Access

Interaction between Mesenchymal Stem Cells and Intervertebral Disc Microenvironment: From Cell Therapy to Tissue Engineering

Gianluca Vadalà,  Luca Ambrosio,  Fabrizio Russo,  Rocco Papalia,  Vincenzo Denaro, 
  • First Published: 10 September 2019
Research Article
Open Access

Identification of WNT16 as a Predictable Biomarker for Accelerated Osteogenic Differentiation of Tonsil-Derived Mesenchymal Stem Cells In Vitro

Yu-Hee Kim,  Kyung-Ah Cho,  Hyun-Ji Lee,  Minhwa Park,  Han Su Kim,  Joo-Won Park,  So-Youn Woo,  Kyung-Ha Ryu, 
  • First Published: 10 September 2019
Editorial
Open Access

Mesenchymal Stem Cell Based Regenerative Treatment of the Knee: From Basic Science to Clinics

Johannes Zellner,  Brian Johnstone,  Frank Barry,  Henning Madry, 
  • First Published: 09 September 2019
Research Article
Open Access

MSC-Derived Exosome Promotes M2 Polarization and Enhances Cutaneous Wound Healing

Xiaoning He,  Zhiwei Dong,  Yina Cao,  Han Wang,  Shiyu Liu,  Li Liao,  Yan Jin,  Lin Yuan,  Bei Li, 
  • First Published: 09 September 2019
Research Article
Open Access

Transplantation of Human Urine-Derived Stem Cells Ameliorates Erectile Function and Cavernosal Endothelial Function by Promoting Autophagy of Corpus Cavernosal Endothelial Cells in Diabetic Erectile Dysfunction Rats

Chi Zhang,  Daosheng Luo,  Tingting Li,  Qiyun Yang,  Yun Xie,  Haicheng Chen,  Linyan Lv,  Jiahui Yao,  Cuncan Deng,  Xiaoyan Liang,  Rongpei Wu,  Xiangzhou Sun,  Yuanyuan Zhang,  Chunhua Deng,  Guihua Liu, 
  • First Published: 09 September 2019
Clinical Study
Open Access

The Role of Autologous Dermal Micrografts in Regenerative Surgery: A Clinical Experimental Study

Marco Mario Tresoldi,  Antonio Graziano,  Alberto Malovini,  Angela Faga,  Giovanni Nicoletti, 
  • First Published: 08 September 2019
Research Article
Open Access

Melatonin Rescued Reactive Oxygen Species-Impaired Osteogenesis of Human Bone Marrow Mesenchymal Stem Cells in the Presence of Tumor Necrosis Factor-Alpha

Xianjian Qiu,  Xudong Wang,  Jincheng Qiu,  Yuanxin Zhu,  Tongzhou Liang,  Bo Gao,  Zizhao Wu,  Chengjie Lian,  Yan Peng,  Anjing Liang,  Peiqiang Su,  Dongsheng Huang, 
  • First Published: 05 September 2019
Research Article
Open Access

Designing Microfluidic Devices to Sort Haematopoietic Stem Cells Based on Their Mechanical Properties

Mingming Du,  Dean Kavanagh,  Zhibing Zhang,  Neena Kalia, 
  • First Published: 05 September 2019
Research Article
Open Access

Development of Bifunctional Three-Dimensional Cysts from Chemically Induced Liver Progenitors

Yu Huang,  Yusuke Sakai,  Takanobu Hara,  Takeshi Katsuda,  Takahiro Ochiya,  Tomohiko Adachi,  Masaaki Hidaka,  Wei-Li Gu,  Susumu Eguchi, 
  • First Published: 03 September 2019
Research Article
Open Access

High-Dose Neural Stem/Progenitor Cell Transplantation Increases Engraftment and Neuronal Distribution and Promotes Functional Recovery in Rats after Acutely Severe Spinal Cord Injury

Taoyang Yuan,  Qian Liu,  Jie Kang,  Hua Gao,  Songbai Gui, 
  • First Published: 02 September 2019
Research Article
Open Access

Achilles Tendon Repair by Decellularized and Engineered Xenografts in a Rabbit Model

Marta Bottagisio,  Daniele D’Arrigo,  Giuseppe Talò,  Matilde Bongio,  Marco Ferroni,  Federica Boschetti,  Matteo Moretti,  Arianna B. Lovati, 
  • First Published: 29 August 2019
Research Article
Open Access

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells

Nihal AlMuraikhi,  Dalia Ali,  Radhakrishnan Vishnubalaji,  Muthurangan Manikandan,  Muhammad Atteya,  Abdulaziz Siyal,  Musaad Alfayez,  Abdullah Aldahmash,  Moustapha Kassem,  Nehad M. Alajez, 
  • First Published: 22 August 2019
Research Article
Open Access

Mesenchymal Stromal Cells Are More Effective Than Their Extracellular Vesicles at Reducing Lung Injury Regardless of Acute Respiratory Distress Syndrome Etiology

Johnatas D. Silva,  Ligia L. de Castro,  Cassia L. Braga,  Gisele P. Oliveira,  Stefano A. Trivelin,  Carlos M. Barbosa-Junior,  Marcelo M. Morales,  Claudia C. dos Santos,  Daniel J. Weiss,  Miquéias Lopes-Pacheco,  Fernanda F. Cruz,  Patricia R. M. Rocco, 
  • First Published: 21 August 2019
Research Article
Open Access

Preconditioning of Rat Bone Marrow-Derived Mesenchymal Stromal Cells with Toll-Like Receptor Agonists

Fabiana Evaristo-Mendonça,  Gabriela Sardella-Silva,  Tais Hanae Kasai-Brunswick,  Raquel Maria Pereira Campos,  Pablo Domizi,  Marcelo Felippe Santiago,  Ricardo Augusto de Melo Reis,  Rosalia Mendez-Otero,  Victor Túlio Ribeiro-Resende,  Pedro Moreno Pimentel-Coelho, 
  • First Published: 19 August 2019

Research Article
Open Access

Isolation, Characterization, and Safety Evaluation of Human Skin-Derived Precursors from an Adherent Monolayer Culture System

Ru Dai,  Wei Hua,  Wei Chen,  Lidan Xiong,  Li Li,  Yiming Li, 
  • First Published: 19 August 2019
Review Article
Open Access

Minimally Manipulated Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Systematic Review of Clinical Evidence

B. Di Matteo,  F. Vandenbulcke,  N. D. Vitale,  F. Iacono,  K. Ashmore,  M. Marcacci,  E. Kon, 
  • First Published: 14 August 2019
Research Article
Open Access

Adipose-Derived Stem Cells from Fat Tissue of Breast Cancer Microenvironment Present Altered Adipogenic Differentiation Capabilities

Federica Rey,  Elena Lesma,  Daniela Massihnia,  Emilio Ciusani,  Sara Nava,  Chiara Vasco,  Ghina Al Haj,  Giorgio Ghilardi,  Enrico Opocher,  Alfredo Gorio,  Stephana Carelli,  Anna Maria Di Giulio, 
  • First Published: 14 August 2019
Review Article
Open Access

Human Amnion Epithelial Cell Therapy for Chronic Liver Disease

Neil Andrewartha,  George Yeoh, 
  • First Published: 07 August 2019
Erratum
Open Access

Erratum to “Epithelial-Mesenchymal Transition Promotes the Differentiation Potential of Xenopus tropicalis Immature Sertoli Cells”

Thi Minh Xuan Nguyen,  Marketa Vegrichtova,  Tereza Tlapakova,  Magdalena Krulova,  Vladimir Krylov, 
  • First Published: 06 August 2019

Research Article
Open Access

The Antibiotic Bacitracin Protects Human Intestinal Epithelial Cells and Stem Cell-Derived Intestinal Organoids from Clostridium difficile Toxin TcdB

Ziyu Zhu,  Leonie Schnell,  Bastian Müller,  Martin Müller,  Panagiotis Papatheodorou,  Holger Barth, 
  • First Published: 05 August 2019
Research Article
Open Access

Mesenchymal Stem Cell Therapy Facilitates Donor Lung Preservation by Reducing Oxidative Damage during Ischemia

Natalia Pacienza,  Diego Santa-Cruz,  Ricardo Malvicini,  Oscar Robledo,  Gastón Lemus-Larralde,  Alejandro Bertolotti,  Martín Marcos,  Gustavo Yannarelli, 
  • First Published: 05 August 2019
Review Article
Open Access

Enhancing Mesenchymal Stromal Cell Immunomodulation for Treating Conditions Influenced by the Immune System

Bella S. Guerrouahen,  Heba Sidahmed,  Asma Al Sulaiti,  Moza Al Khulaifi,  Chiara Cugno, 
  • First Published: 05 August 2019
Research Article
Open Access

A High-Throughput Method as a Diagnostic Tool for HIV Detection in Patient-Specific Induced Pluripotent Stem Cells Generated by Different Reprogramming Methods

Daniela Hübscher,  Sabine Rebs,  Luis Haupt,  Thomas Borchert,  Celina Isabell Guessoum,  Franziska Treu,  Steffen Köhne,  Andreas Maus,  Mario Hambrecht,  Samuel Sossalla,  Ralf Dressel,  Angela Uy,  Mark Jakob,  Gerd Hasenfuss,  Katrin Streckfuss-Bömeke, 
  • First Published: 05 August 2019
Research Article
Open Access

The Analysis of In Vivo Aging in Human Bone Marrow Mesenchymal Stromal Cells Using Colony-Forming Unit-Fibroblast Assay and the CD45lowCD271+ Phenotype

Payal Ganguly,  Jehan J. El-Jawhari,  Agata N. Burska,  Frederique Ponchel,  Peter V. Giannoudis,  Elena A. Jones, 
  • First Published: 01 August 2019
Research Article
Open Access

Therapeutic Effects of Intravenous Injection of Fresh and Frozen Thawed HO-1-Overexpressed Ad-MSCs in Dogs with Acute Spinal Cord Injury

Imdad Ullah Khan,  Yongseok Yoon,  Kyeung Uk Choi,  Kwang Rae Jo,  Namyul Kim,  Eunbee Lee,  Wan Hee Kim,  Oh-Kyeong Kweon, 
  • First Published: 01 August 2019
Research Article
Open Access

Local Application of Semaphorin 3A Combined with Adipose-Derived Stem Cell Sheet and Anorganic Bovine Bone Granules Enhances Bone Regeneration in Type 2 Diabetes Mellitus Rats

Xiaoru Xu,  Kaixiu Fang,  Lifeng Wang,  Xiangwei Liu,  Yuchao Zhou,  Yingliang Song, 
  • First Published: 31 July 2019
Research Article
Open Access

The Potential Role of Quorum Sensing in Clonal Growth and Subsequent Expansion of Bone Marrow Stromal Cell Strains in Culture

Maurizio Alimandi,  Luca Pierelli,  Valentina Pino,  Stefano Gentileschi,  Benedetto Sacchetti, 
  • First Published: 31 July 2019
Research Article
Open Access

Bioinformatic Analysis of Transcriptomic Data Reveals Novel Key Genes Regulating Osteogenic Differentiation of Human Adipose Stem Cells

Jinluo Cheng,  Xinyuan Zhao,  Juan Liu,  Li Cui,  Yanfeng Zhu,  Xiaoqing Yuan,  Jianbo Gao,  Yunfeng Du,  Xinmin Yan,  Shen Hu, 
  • First Published: 31 July 2019
Review Article
Open Access

Current Advances in Red Blood Cell Generation Using Stem Cells from Diverse Sources

Yoojin Seo,  Kyung-Hwa Shin,  Hyung Hoi Kim,  Hyung-Sik Kim, 
  • First Published: 29 July 2019
Research Article
Open Access

Dexamethasone Provides Effective Immunosuppression for Improved Survival of Retinal Organoids after Epiretinal Transplantation

Bikun Xian,  Ziming Luo,  Kaijing Li,  Kang Li,  Mingjun Tang,  Runcai Yang,  Shoutao Lu,  Haijun Zhang,  Jian Ge, 
  • First Published: 25 July 2019
Clinical Study
Open Access

Safety and Feasibility of Repeated Intrathecal Allogeneic Bone Marrow-Derived Mesenchymal Stromal Cells in Patients with Neurological Diseases

Kuang Pan,  Lingna Deng,  Peiying Chen,  Qingxia Peng,  Jingrui Pan,  Yanfeng Wu,  Yidong Wang, 
  • First Published: 25 July 2019
Review Article
Open Access

A Review on the Effect of Plant Extract on Mesenchymal Stem Cell Proliferation and Differentiation

Bhuvan Saud,  Rajani Malla,  Kanti Shrestha, 
  • First Published: 24 July 2019
Research Article
Open Access

Bone Marrow-Derived CD44+ Cells Migrate to Tissue-Engineered Constructs via SDF-1/CXCR4-JNK Pathway and Aid Bone Repair

Yanzhu Lu,  Junchao Xing,  Xiaolong Yin,  Xiaobo Zhu,  Aijun Yang,  Jiyue Luo,  Jing Gou,  Shiwu Dong,  Jianzhong Xu,  Tianyong Hou, 
  • First Published: 24 July 2019
Review Article
Open Access

Protein Kinases and Their Inhibitors in Pluripotent Stem Cell Fate Regulation

Jungwoon Lee,  Young-Jun Park,  Haiyoung Jung, 
  • First Published: 24 July 2019
Research Article
Open Access

Mesenchymal Stem Cells Exhibit Both a Proinflammatory and Anti-Inflammatory Effect on Saccular Aneurysm Formation in a Rabbit Model

Michael B. Avery,  Brooke L. Belanger,  Amy Bromley,  Arindom Sen,  Alim P. Mitha, 
  • First Published: 22 July 2019
Research Article
Open Access

Reprogramming of Adult Retinal Müller Glial Cells into Human-Induced Pluripotent Stem Cells as an Efficient Source of Retinal Cells

Amélie Slembrouck-Brec,  Amélie Rodrigues,  Oriane Rabesandratana,  Giuliana Gagliardi,  Céline Nanteau,  Stéphane Fouquet,  Gilles Thuret,  Sacha Reichman,  Gael Orieux,  Olivier Goureau, 
  • First Published: 15 July 2019
Review Article
Open Access

Macrophages Are Key Regulators of Stem Cells during Skeletal Muscle Regeneration and Diseases

Junio Dort,  Paul Fabre,  Thomas Molina,  Nicolas A. Dumont, 
  • First Published: 14 July 2019
Research Article
Open Access

Histone Arginine Methylation-Mediated Epigenetic Regulation of Discoidin Domain Receptor 2 Controls the Senescence of Human Bone Marrow Mesenchymal Stem Cells

Zhenyu Xu,  Wenming Wu,  Fang Shen,  Yue Yu,  Yue Wang,  Charlie Xiang, 
  • First Published: 11 July 2019
Research Article
Open Access

Identification of Aberrantly Expressed Genes during Aging in Rat Nucleus Pulposus Cells

Shi Cheng,  Xiaochuan Li,  Linghan Lin,  Zhiwei Jia,  Yachao Zhao,  Deli Wang,  Dike Ruan,  Yu Zhang, 
  • First Published: 10 July 2019
Research Article
Open Access

Mechanical Stretch Promotes the Osteogenic Differentiation of Bone Mesenchymal Stem Cells Induced by Erythropoietin

Yong-Bin He,  Sheng-Yao Liu,  Song-Yun Deng,  Li-Peng Kuang,  Shao-Yong Xu,  Zhe Li,  Lei Xu,  Wei Liu,  Guo-Xin Ni, 
  • First Published: 07 July 2019
Research Article
Open Access

Gestational Tissue-Derived Human Mesenchymal Stem Cells Use Distinct Combinations of Bioactive Molecules to Suppress the Proliferation of Human Hepatoblastoma and Colorectal Cancer Cells

Nitchapon Paiboon,  Witchayaporn Kamprom,  Sirikul Manochantr,  Chairat Tantrawatpan,  Duangrat Tantikanlayaporn,  Sittiruk Roytrakul,  Pakpoom Kheolamai, 
  • First Published: 04 July 2019
Editorial
Open Access

Heterogeneity of MSC: Origin, Molecular Identities, and Functionality

Xueqing Liu,  Tao Rui,  Sicai Zhang,  Zhaoping Ding, 
  • First Published: 02 July 2019
Research Article
Open Access

Kupffer Cells Promote the Differentiation of Adult Liver Hematopoietic Stem and Progenitor Cells into Lymphocytes via ICAM-1 and LFA-1 Interaction

Deping Meng,  Yuhong Qin,  Nan Lu,  Keke Fang,  Yuan Hu,  Zhigang Tian,  Cai Zhang, 
  • First Published: 01 July 2019
Research Article
Open Access

Atypical Mesenchymal Stromal Cell Responses to Topographic Modifications of Titanium Biomaterials Indicate Cytoskeletal- and Genetic Plasticity-Based Heterogeneity of Cells

Mohammad R. Khan,  Nicola Mordan,  Mohamed Parkar,  Vehid Salih,  Nikolaos Donos,  Peter M. Brett, 
  • First Published: 01 July 2019
Review Article
Open Access

Hyaluronan-Based Grafting Strategies for Liver Stem Cell Therapy and Tracking Methods

Lorenzo Nevi,  Samira Safarikia,  Sabina Di Matteo,  Francesca Biancaniello,  Michele Francesco Chiappetta,  Vincenzo Cardinale, 
  • First Published: 01 July 2019
Research Article
Open Access

Schwann Cell-Like Cells Derived from Human Amniotic Mesenchymal Stem Cells Promote Peripheral Nerve Regeneration through a MicroRNA-214/c-Jun Pathway

Wei Chen,  Shune Xiao,  Zairong Wei,  Chengliang Deng,  Kaiyu Nie,  Dali Wang, 
  • First Published: 01 July 2019
Research Article
Open Access

Promoting Osteogenic Differentiation of Human Adipose-Derived Stem Cells by Altering the Expression of Exosomal miRNA

Shude Yang,  Shu Guo,  Shuang Tong,  Xu Sun, 
  • First Published: 01 July 2019
Review Article
Open Access

Functional Skin Grafts: Where Biomaterials Meet Stem Cells

Amtoj Kaur,  Swati Midha,  Shibashish Giri,  Sujata Mohanty, 
  • First Published: 01 July 2019
Research Article
Open Access

Characterization of the Angiogenic Potential of Human Regulatory Macrophages (Mreg) after Ischemia/Reperfusion Injury In Vitro

Lars Hummitzsch,  Karina Zitta,  Rene Rusch,  Jochen Cremer,  Markus Steinfath,  Justus Gross,  Fred Fandrich,  Rouven Berndt,  Martin Albrecht, 
  • First Published: 25 June 2019
Review Article
Open Access

Autologous Hematopoietic Cell Transplantation in Multiple Sclerosis: Changing Paradigms in the Era of Novel Agents

Maria Gavriilaki,  Ioanna Sakellari,  Eleni Gavriilaki,  Vasilios K. Kimiskidis,  Achilles Anagnostopoulos, 
  • First Published: 24 June 2019
Research Article
Open Access

Characterization of Different Sources of Human MSCs Expanded in Serum-Free Conditions with Quantification of Chondrogenic Induction in 3D

Hugo Fabre,  Maxime Ducret,  Olivier Degoul,  Jonathan Rodriguez,  Emeline Perrier-Groult,  Elisabeth Aubert-Foucher,  Marielle Pasdeloup,  Céline Auxenfans,  Colin McGuckin,  Nico Forraz,  Frédéric Mallein-Gerin, 
  • First Published: 20 June 2019
Editorial
Open Access

Stem Cells and Liver Diseases

Zongyi Hu,  Yuchen Xia,  So Gun Hong,  Emmanuel Thomas,  Dali Li, 
  • First Published: 20 June 2019
Research Article
Open Access

Generation of iPSCs by Nonintegrative RNA-Based Reprogramming Techniques: Benefits of Self-Replicating RNA versus Synthetic mRNA

Heidrun Steinle,  Marbod Weber,  Andreas Behring,  Ulrike Mau-Holzmann,  Christian Schlensak,  Hans Peter Wendel,  Meltem Avci-Adali, 
  • First Published: 19 June 2019
Research Article
Open Access

Chemotherapeutic Stress Induces Transdifferentiation of Glioblastoma Cells to Endothelial Cells and Promotes Vascular Mimicry

Shivani Baisiwala,  Brenda Auffinger,  Seamus P. Caragher,  Jack M. Shireman,  Riasat Ahsan,  Gina Lee,  Tanwir Hasan,  Cheol Park,  Miranda R. Saathoff,  Anne C. Christensen,  Atique U. Ahmed, 
  • First Published: 18 June 2019
Research Article
Open Access

Development of Collagen-Based 3D Matrix for Gastrointestinal Tract-Derived Organoid Culture

Joo Hyun Jee,  Dong Hyeon Lee,  Jisu Ko,  Soojung Hahn,  Sang Yun Jeong,  Han Kyung Kim,  Enoch Park,  Seon Young Choi,  Sukin Jeong,  Joong Woon Lee,  Han-Jun Cho,  Min-Soo Kwon,  Jongman Yoo, 
  • First Published: 13 June 2019
Research Article
Open Access

Detection of Human Microchimerism following Allogeneic Cell Transplantation Using Droplet Digital PCR

Catherine A. Lombard,  Alexandre Fabre,  Jérôme Ambroise,  Joachim Ravau,  Floriane André,  Nawal Jazouli,  Mustapha Najimi,  Xavier Stéphenne,  Françoise Smets,  Jean-Luc Vaerman,  Etienne M. Sokal, 
  • First Published: 12 June 2019
Editorial
Open Access

Metabolic Control of Stemness and Differentiation

Viviana Moresi,  Athanassia Sotiropoulos,  Giuseppina Caretti,  Alexandra Harvey, 
  • First Published: 12 June 2019
Research Article
Open Access

The Role of CDR1as in Proliferation and Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells

Lunyu Yang,  Zhang Bin,  Shi Hui,  Li Rong,  Benshuai You,  Peipei Wu,  Xinye Han,  Hui Qian,  Wenrong Xu, 
  • First Published: 12 June 2019
Review Article
Open Access

The Application of Induced Pluripotent Stem Cells in Pathogenesis Study and Gene Therapy for Vascular Disorders: Current Progress and Future Challenges

Guang-Yin Peng,  Yang Lin,  Jing-Jing Li,  Ying Wang,  Hao-Yue Huang,  Zhen-Ya Shen, 
  • First Published: 12 June 2019
Review Article
Open Access

Stem Cell-Derived Hepatocyte-Like Cells as Model for Viral Hepatitis Research

Jingjing Wang,  Bingqian Qu,  Fang Zhang,  Cindy Zhang,  Wanyan Deng,  Viet Loan Dao Thi,  Yuchen Xia, 
  • First Published: 12 June 2019
Review Article
Open Access

The Immunomodulatory Potential of Wharton’s Jelly Mesenchymal Stem/Stromal Cells

Fernanda Vieira Paladino,  Juliana de Moraes Rodrigues,  Aline da Silva,  Anna Carla Goldberg, 
  • First Published: 11 June 2019
Research Article
Open Access

IL-10 Gene-Modified Human Amniotic Mesenchymal Stem Cells Augment Regenerative Wound Healing by Multiple Synergistic Effects

Shune Xiao,  Guangtao Huang,  Zairong Wei,  Kaiyu Nie,  Zhiyuan Liu,  Chengliang Deng,  Dali Wang, 
  • First Published: 11 June 2019
Research Article
Open Access

Adipose Tissue-Derived Stem Cells Have the Ability to Differentiate into Alveolar Epithelial Cells and Ameliorate Lung Injury Caused by Elastase-Induced Emphysema in Mice

Eriko Fukui,  Soichiro Funaki,  Kenji Kimura,  Toru Momozane,  Atsuomi Kimura,  Ryota Chijimatsu,  Ryu Kanzaki,  Takashi Kanou,  Naoko Ose,  Masato Minami,  Shigeru Miyagawa,  Yoshiki Sawa,  Meinoshin Okumura,  Yasushi Shintani, 
  • First Published: 10 June 2019
Research Article
Open Access

Fetal Dermal Mesenchymal Stem Cell-Derived Exosomes Accelerate Cutaneous Wound Healing by Activating Notch Signaling

Xiao Wang,  Ya Jiao,  Yi Pan,  Longxiao Zhang,  Hongmin Gong,  Yongjun Qi,  Maoying Wang,  Huiping Gong,  Mingju Shao,  Xinglei Wang,  Duyin Jiang, 
  • First Published: 10 June 2019
Clinical Study
Open Access

Alveolar Differentiation Potency of Human Distal Airway Stem Cells Is Associated with Pulmonary Pathological Conditions

Yujia Wang,  Yi Lu,  Yingchuan Wu,  Yufen Sun,  Yueqing Zhou,  Qiwang Ma,  Yawen Zheng,  Qianwen Yu,  Yujie Cao,  Guangdong Chen,  Ting Zhang,  Xiaotian Dai,  Tao Ren,  Yu Ma,  Wei Zuo, 
  • First Published: 09 June 2019
Editorial
Open Access

Identification and Targeting of Stem Cell-Activated Pathways in Cancer Therapy

Alfredo Budillon,  Steven Curley,  Roberta Fusco,  Rita Mancini, 
  • First Published: 04 June 2019
Review Article
Open Access

New Insights on Properties and Spatial Distributions of Skeletal Stem Cells

Jun-qi Liu,  Qi-wen Li,  Zhen Tan, 
  • First Published: 03 June 2019
Review Article
Open Access

Potential for Isolation of Immortalized Hepatocyte Cell Lines by Liver-Directed In Vivo Gene Delivery of Transposons in Mice

Masahiro Sato,  Issei Saitoh,  Emi Inada,  Shingo Nakamura,  Satoshi Watanabe, 
  • First Published: 02 June 2019
Research Article
Open Access

MAPK p38alpha Kinase Influences Haematopoiesis in Embryonic Stem Cells

Kateřina Štefková,  Markéta Hanáčková,  Jan Kučera,  Katarzyna Anna Radaszkiewicz,  Barbora Ambrůžová,  Lukáš Kubala,  Jiří Pacherník, 
  • First Published: 02 June 2019
Editorial
Open Access

Engineering Cell Systems

Tiago G. Fernandes,  Ricardo P. Baptista,  Howard Kim, 
  • First Published: 02 June 2019
Research Article
Open Access

A Feasibility Study on the Use of Equine Chondrogenic Induced Mesenchymal Stem Cells as a Treatment for Natural Occurring Osteoarthritis in Dogs

Robert Daems,  Lore Van Hecke,  Ilona Schwarzkopf,  Eva Depuydt,  Sarah Y. Broeckx,  Michael David,  Charlotte Beerts,  Peter Vandekerckhove,  Jan H. Spaas, 
  • First Published: 02 June 2019
Research Article
Open Access

Activated B Lymphocyte Inhibited the Osteoblastogenesis of Bone Mesenchymal Stem Cells by Notch Signaling

Mengxue Pan,  Wei Hong,  Ye Yao,  Xiaoxue Gao,  Yi Zhou,  Guoxiang Fu,  Yuanchuang Li,  Qiang Guo,  Xinxin Rao,  Peiyuan Tang,  Shengzhi Chen,  Weifang Jin,  Guoqiang Hua,  Jianjun Gao,  Xiaoya Xu, 
  • First Published: 02 June 2019
Research Article
Open Access

Influence of Lineage-Negative Stem Cell Therapy on Articulatory Functions in ALS Patients

Wioletta Pawlukowska,  Bartłomiej Baumert,  Monika Gołąb-Janowska,  Anna Sobuś,  Agnieszka Wełnicka,  Agnieszka Meller,  Karolina Machowska-Sempruch,  Alicja Zawiślak,  Karolina Łuczkowska,  Sławomir Milczarek,  Bogumiła Osękowska,  Edyta Paczkowska,  Iwona Rotter,  Przemysław Nowacki,  Bogusław Machaliński, 
  • First Published: 02 June 2019
Research Article
Open Access

Protease-Activated Receptor Type 1 Activation Enhances Osteogenic Activity in Human Periodontal Ligament Stem Cells

Emanuel Silva Rovai,  Lucas Macedo Batitucci Ambrósio,  Bruno Nunes de França,  Letícia Rodrigues de Oliveira,  Letícia Miquelitto Gasparoni,  Carla Renata Sipert,  Marinella Holzhausen, 
  • First Published: 02 June 2019
Review Article
Open Access

Emerging Role of Mesenchymal Stromal Cell-Derived Extracellular Vesicles in Pathogenesis of Haematological Malignancies

Juçara Gastaldi Cominal,  Maira da Costa Cacemiro,  Belinda Pinto-Simões,  Hans-Jochem Kolb,  Kelen Cristina Ribeiro Malmegrim,  Fabíola Attié de Castro, 
  • First Published: 02 June 2019
Research Article
Open Access

Human Liver-Derived Stem Cells Improve Fibrosis and Inflammation Associated with Nonalcoholic Steatohepatitis

Stefania Bruno,  Maria Beatriz Herrera Sanchez,  Chiara Pasquino,  Marta Tapparo,  Massimo Cedrino,  Ciro Tetta,  Giovanni Camussi, 
  • First Published: 02 June 2019
Research Article
Open Access

Endometriotic Peritoneal Fluid Promotes Myofibroblast Differentiation of Endometrial Mesenchymal Stem Cells

Zhenzhen Zhang,  Luxuan Suo,  Yabing Chen,  Li Zhu,  Guiping Wan,  Xiaodong Han, 
  • First Published: 02 June 2019
Research Article
Open Access

Exosomes Derived from Mesenchymal Stem Cells Ameliorate Hypoxia/Reoxygenation-Injured ECs via Transferring MicroRNA-126

Qunwen Pan,  Yan Wang,  Qing Lan,  Weiquan Wu,  Zhenxuan Li,  Xiaotang Ma,  Liming Yu, 
  • First Published: 02 June 2019
Review Article
Open Access

Stem cells in Osteoporosis: From Biology to New Therapeutic Approaches

Vasilis Paspaliaris,  George Kolios, 
  • First Published: 02 June 2019
Erratum
Open Access

Erratum to “Mesenchymal Stem Cells Coated by the Extracellular Matrix Promote Wound Healing in Diabetic Rats”

Linghao Wang,  Fang Wang,  Liling Zhao,  Wenjun Yang,  Xinxing Wan,  Chun Yue,  Zhaohui Mo, 
  • First Published: 02 June 2019

Research Article
Open Access

Stem Cells and Platelet-Rich Plasma Enhance the Healing Process of Tendinitis in Mice

Rosangela Alquieri Fedato,  Júlio César Francisco,  Gabriel Sliva,  Lúcia de Noronha,  Márcia Olandoski,  Jose Rocha Faria Neto,  Priscila Elias Ferreira,  Rossana Baggio Simeoni,  Eltyeb Abdelwahid,  Katherine Athayde Teixeira de Carvalho,  Luiz César Guarita-Souza, 
  • First Published: 02 June 2019
Research Article
Open Access

Luteolin-7-glucoside Promotes Human Epidermal Stem Cell Proliferation by Upregulating β-Catenin, c-Myc, and Cyclin Expression

Dapeng Wan,  Yi Fu,  Yingying Le,  Ping Zhang,  Jihui Ju,  Benyuan Wang,  Guangliang Zhang,  Zhaodong Wang,  Hao Su,  Ling Wang,  Ruixing Hou, 
  • First Published: 02 June 2019
Research Article
Open Access

MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo

Karolin Walter,  Kanishka Tiwary,  Marija Trajkovic-Arsic,  Ana Hidalgo-Sastre,  Laura Dierichs,  Sven T. Liffers,  Jiangning Gu,  Johann Gout,  Lucas-Alexander Schulte,  Jan Münch,  Thomas Seufferlein,  Bruno Sainz Jr.,  Jens T. Siveke,  Eva Rodriguez-Aznar,  Patrick C. Hermann, 
  • First Published: 02 June 2019
Research Article
Open Access

Oxygen Regulates Human Pluripotent Stem Cell Metabolic Flux

Jarmon G. Lees,  Timothy S. Cliff,  Amanda Gammilonghi,  James G. Ryall,  Stephen Dalton,  David K. Gardner,  Alexandra J. Harvey, 
  • First Published: 19 May 2019
Research Article
Open Access

Pharmacological Transdifferentiation of Human Nasal Olfactory Stem Cells into Dopaminergic Neurons

Audrey Chabrat,  Emmanuelle Lacassagne,  Rodolphe Billiras,  Sophie Landron,  Amélie Pontisso-Mahout,  Hélène Darville,  Alain Dupront,  Francis Coge,  Esther Schenker,  David Piwnica,  Emmanuel Nivet,  François Féron,  Clotilde Mannoury la Cour, 
  • First Published: 19 May 2019
Research Article
Open Access

Pancreatic Ductal Organoids React Kras Dependent to the Removal of Tumor Suppressive Roadblocks

Lukas Perkhofer,  Melanie Engler,  Johann Gout,  Frank Arnold,  Mareen Morawe,  Markus Breunig,  Thomas Seufferlein,  Alexander Kleger,  Pierre-Olivier Frappart, 
  • First Published: 19 May 2019
Research Article
Open Access

Human Menstrual Blood-Derived Stem Cells Inhibit the Proliferation of HeLa Cells via TGF-β1-Mediated JNK/P21 Signaling Pathways

Qian-Yu Liu,  Feng Ruan,  Jing-Yuan Li,  Li Wei,  Ping Hu,  Hou-Wen Chen,  Quan-Wen Liu, 
  • First Published: 19 May 2019
Research Article
Open Access

Metabolic Phenotyping of Adipose-Derived Stem Cells Reveals a Unique Signature and Intrinsic Differences between Fat Pads

Camille Lefevre,  Baptiste Panthu,  Danielle Naville,  Sylvie Guibert,  Claudie Pinteur,  Bénédicte Elena-Herrmann,  Hubert Vidal,  Gilles J. P. Rautureau,  Anne Mey, 
  • First Published: 14 May 2019
Research Article
Open Access

The Influence of Cell Source and Donor Age on the Tenogenic Potential and Chemokine Secretion of Human Mesenchymal Stromal Cells

Weronika Zarychta-Wiśniewska,  Anna Burdzińska,  Katarzyna Zielniok,  Marta Koblowska,  Kamila Gala,  Piotr Pędzisz,  Roksana Iwanicka- Nowicka,  Anna Fogtman,  Aleksandra Aksamit,  Agnieszka Kulesza,  Aleksandra Zołocińska,  Leszek Pączek, 
  • First Published: 07 May 2019
Review Article
Open Access

Advances in Hepatic Tissue Bioengineering with Decellularized Liver Bioscaffold

Erik Aranha Rossi,  Luiz Fernando Quintanilha,  Carolina Kymie Vasques Nonaka,  Bruno Solano de Freitas Souza, 
  • First Published: 06 May 2019
Review Article
Open Access

Understanding the Journey of Human Hematopoietic Stem Cell Development

Akhilesh Kumar,  Saritha S. D’Souza,  Abir S. Thakur, 
  • First Published: 06 May 2019
Research Article
Open Access

Inhibition of the Notch1 Pathway Promotes the Effects of Nucleus Pulposus Cell-Derived Exosomes on the Differentiation of Mesenchymal Stem Cells into Nucleus Pulposus-Like Cells in Rats

Wei-ren Lan,  Sai Pan,  Hai-yin Li,  Chao Sun,  Xian Chang,  Kang Lu,  Chang-qing Jiang,  Rui Zuo,  Yue Zhou,  Chang-qing Li, 
  • First Published: 06 May 2019
Review Article
Open Access

Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell Reprogramming

James Spyrou,  David K. Gardner,  Alexandra J. Harvey, 
  • First Published: 05 May 2019
Research Article
Open Access

Stem Cell Therapy: A Compassionate Use Program in Perianal Fistula

M. D. Herreros,  D. Garcia-Olmo,  H. Guadalajara,  T. Georgiev-Hristov,  L. Brandariz,  M. Garcia-Arranz, 
  • First Published: 05 May 2019
Research Article
Open Access

Directional Topography Influences Adipose Mesenchymal Stromal Cell Plasticity: Prospects for Tissue Engineering and Fibrosis

Gabriel Romero Liguori,  Qihui Zhou,  Tácia Tavares Aquinas Liguori,  Guilherme Garcia Barros,  Philipp Till Kühn,  Luiz Felipe Pinho Moreira,  Patrick van Rijn,  Martin C. Harmsen, 
  • First Published: 05 May 2019
Research Article
Open Access

Long Noncoding RNA H19 Participates in the Regulation of Adipose-Derived Stem Cells Cartilage Differentiation

Hai-lin Pang,  Qian-qian Zhao,  Yu Ma,  Yong-li Song,  Jie Min,  Jian-rong Lu,  Hang Li,  Da-qing Zhao, 
  • First Published: 05 May 2019
Review Article
Open Access

Employing Endogenous NSCs to Promote Recovery of Spinal Cord Injury

Sumei Liu,  Zhiguo Chen, 
  • First Published: 05 May 2019
Research Article
Open Access

Epithelial-Mesenchymal Transition Promotes the Differentiation Potential of Xenopus tropicalis Immature Sertoli Cells

Thi Minh Xuan Nguyen,  Marketa Vegrichtova,  Tereza Tlapakova,  Magdalena Krulova,  Vladimir Krylov, 
  • First Published: 05 May 2019

Research Article
Open Access

Spontaneously Formed Spheroids from Mouse Compact Bone-Derived Cells Retain Highly Potent Stem Cells with Enhanced Differentiation Capability

Kai Chen,  Xianqi Li,  Ni Li,  Hongwei Dong,  Yiming Zhang,  Michiko Yoshizawa,  Hideaki Kagami, 
  • First Published: 05 May 2019
Review Article
Open Access

Mesenchymal Stem Cells for Liver Regeneration in Liver Failure: From Experimental Models to Clinical Trials

Maria P. de Miguel,  I. Prieto,  A. Moratilla,  J. Arias,  M. A. Aller, 
  • First Published: 02 May 2019
Review Article
Open Access

Recent Updates on Induced Pluripotent Stem Cells in Hematological Disorders

Methichit Wattanapanitch, 
  • First Published: 02 May 2019
Review Article
Open Access

Mesenchymal Stem Cell-Based Therapy of Inflammatory Lung Diseases: Current Understanding and Future Perspectives

C. Randall Harrell,  Ruxana Sadikot,  Jose Pascual,  Crissy Fellabaum,  Marina Gazdic Jankovic,  Nemanja Jovicic,  Valentin Djonov,  Nebojsa Arsenijevic,  Vladislav Volarevic, 
  • First Published: 02 May 2019
Research Article
Open Access

CFTR Expression Analysis for Subtyping of Human Pancreatic Cancer Organoids

Alexander Hennig,  Laura Wolf,  Beatrix Jahnke,  Heike Polster,  Therese Seidlitz,  Kristin Werner,  Daniela E. Aust,  Jochen Hampe,  Marius Distler,  Jürgen Weitz,  Daniel E. Stange,  Thilo Welsch, 
  • First Published: 02 May 2019

Research Article
Open Access

Oct4 Gene Expression in Primary Colorectal Cancer Promotes Liver Metastasis

Shiki Fujino,  Norikatsu Miyoshi, 
  • First Published: 02 May 2019
Research Article
Open Access

Wharton’s Jelly Mesenchymal Stem Cell Administration Improves Quality of Life and Self-Sufficiency in Children with Cerebral Palsy: Results from a Retrospective Study

Dariusz Boruczkowski,  Izabela Zdolińska-Malinowska, 
  • First Published: 02 May 2019
Research Article
Open Access

Prognostic Factors for Clinical Response in Systemic Lupus Erythematosus Patients Treated by Allogeneic Mesenchymal Stem Cells

Lihui Wen,  Myriam Labopin,  Manuela Badoglio,  Dandan Wang,  Lingyun Sun,  Dominique Farge-Bancel, 
  • First Published: 02 May 2019
Research Article
Open Access

Mesenchymal Stem Cells Derived and Cultured from Glioblastoma Multiforme Increase Tregs, Downregulate Th17, and Induce the Tolerogenic Phenotype of Monocyte-Derived Cells

Kalina Tumangelova-Yuzeir,  Emanuil Naydenov,  Ekaterina Ivanova-Todorova,  Ekaterina Krasimirova,  Georgi Vasilev,  Sevdalin Nachev,  Dobroslav Kyurkchiev, 
  • First Published: 02 May 2019
Research Article
Open Access

Intradiscal Injection of Induced Pluripotent Stem Cell-Derived Nucleus Pulposus-Like Cell-Seeded Polymeric Microspheres Promotes Rat Disc Regeneration

Kaishun Xia,  Jian Zhu,  Jianming Hua,  Zhe Gong,  Chao Yu,  Xiaopeng Zhou,  Jingkai Wang,  Xianpeng Huang,  Wei Yu,  Liming Li,  Jianqing Gao,  Qixin Chen,  Fangcai Li,  Chengzhen Liang, 
  • First Published: 02 May 2019
Review Article
Open Access

Perspectives for Clinical Translation of Adipose Stromal/Stem Cells

Mimmi Patrikoski,  Bettina Mannerström,  Susanna Miettinen, 
  • First Published: 02 May 2019
Research Article
Open Access

Construction and Evaluation of a Subcutaneous Splenic Injection Port for Serial Intraportal Vein Cell Delivery in Murine Disease Models

Toshio Miki,  Chika Takano,  Irving M. Garcia,  Brendan H. Grubbs, 
  • First Published: 02 May 2019
Research Article
Open Access

Mechanical Stress Modulates the RANKL/OPG System of Periodontal Ligament Stem Cells via α7 nAChR in Human Deciduous Teeth: An In Vitro Study

Yujiang Chen,  Kuan Yang,  Zhifei Zhou,  Lulu Wang,  Yang Du,  Xiaojing Wang, 
  • First Published: 02 May 2019
Research Article
Open Access

Constructing an Isogenic 3D Human Nephrogenic Progenitor Cell Model Composed of Endothelial, Mesenchymal, and SIX2-Positive Renal Progenitor Cells

Lisa Nguyen,  Lucas-Sebastian Spitzhorn,  James Adjaye, 
  • First Published: 02 May 2019
Research Article
Open Access

Exosomes from Human Gingiva-Derived Mesenchymal Stem Cells Combined with Biodegradable Chitin Conduits Promote Rat Sciatic Nerve Regeneration

Feng Rao,  Dianying Zhang,  Tengjiaozi Fang,  Changfeng Lu,  Bo Wang,  Xiao Ding,  Shuai Wei,  Yiran Zhang,  Wei Pi,  Hailin Xu,  Yanhua Wang,  Baoguo Jiang,  Peixun Zhang, 
  • First Published: 02 May 2019
Corrigendum
Open Access

Corrigendum to “Pulsed Electromagnetic Fields Improve Tenogenic Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells: A Potential Strategy for Tendon Repair—An In Vitro Study”

Antonio Marmotti,  Giuseppe Maria Peretti,  Silvia Mattia,  Laura Mangiavini,  Laura de Girolamo,  Marco Viganò,  Stefania Setti,  Davide Edoardo Bonasia,  Davide Blonna,  Enrico Bellato,  Giovanni Ferrero,  Filippo Castoldi, 
  • First Published: 02 May 2019

Review Article
Open Access

Cend1, a Story with Many Tales: From Regulation of Cell Cycle Progression/Exit of Neural Stem Cells to Brain Structure and Function

Maria Gaitanou,  Katerina Segklia,  Rebecca Matsas, 
  • First Published: 02 May 2019
Research Article
Open Access

Intra-Articular Injection of 2 Different Dosages of Autologous and Allogeneic Bone Marrow- and Umbilical Cord-Derived Mesenchymal Stem Cells Triggers a Variable Inflammatory Response of the Fetlock Joint on 12 Sound Experimental Horses

Lélia Bertoni,  Thomas Branly,  Sandrine Jacquet,  Mélanie Desancé,  Loïc Desquilbet,  Pascaline Rivory,  Daniel-Jean Hartmann,  Jean-Marie Denoix,  Fabrice Audigié,  Philippe Galéra,  Magali Demoor, 
  • First Published: 02 May 2019
Research Article
Open Access

Identification of Macrophage Genotype and Key Biological Pathways in Circulating Angiogenic Cell Transcriptome

Bert R. Everaert,  Steven J. Van Laere,  Robrecht Lembrechts,  Vicky Y. Hoymans,  Jean-Pierre Timmermans,  Christiaan J. Vrints, 
  • First Published: 02 May 2019
Review Article
Open Access

The Best for the Most Important: Maintaining a Pristine Proteome in Stem and Progenitor Cells

Bertal H. Aktas,  Berin Upcin,  Erik Henke,  Manju Padmasekar,  Xuebin Qin,  Süleyman Ergün, 
  • First Published: 02 May 2019
Research Article
Open Access

Does the Harvesting Site Influence the Osteogenic Potential of Mesenchymal Stem Cells?

Van Thi Nguyen,  Irene Tessaro,  Antonio Marmotti,  Camilla Sirtori,  Giuseppe M. Peretti,  Laura Mangiavini, 
  • First Published: 02 May 2019
Research Article
Open Access

Medium Perfusion Flow Improves Osteogenic Commitment of Human Stromal Cells

Alice Pasini,  Joseph Lovecchio,  Giulia Ferretti,  Emanuele Giordano, 
  • First Published: 02 May 2019
Research Article
Open Access

Generation and miRNA Characterization of Equine Induced Pluripotent Stem Cells Derived from Fetal and Adult Multipotent Tissues

Laís Vicari de Figueiredo Pessôa,  Pedro Ratto Lisboa Pires,  Maite del Collado,  Naira Caroline Godoy Pieri,  Kaiana Recchia,  Aline Fernanda Souza,  Felipe Perecin,  Juliano Coelho da Silveira,  André Furugen Cesar de Andrade,  Carlos Eduardo Ambrosio,  Fabiana Fernandes Bressan,  Flavio Vieira Meirelles, 
  • First Published: 02 May 2019
Research Article
Open Access

The Anthrax Toxin Receptor 1 (ANTXR1) Is Enriched in Pancreatic Cancer Stem Cells Derived from Primary Tumor Cultures

Sonia Alcalá,  Paola Martinelli,  Patrick C. Hermann,  Christopher Heeschen,  Bruno Sainz Jr., 
  • First Published: 02 May 2019
Research Article
Open Access

CD73 Expression on Mesenchymal Stem Cells Dictates the Reparative Properties via Its Anti-Inflammatory Activity

Kezhe Tan,  Hongtao Zhu,  Jianfang Zhang,  Weili Ouyang,  Jianfeng Tang,  Youming Zhang,  Linlin Qiu,  Xueqing Liu,  Zhaoping Ding,  Xiaoming Deng, 
  • First Published: 02 May 2019
Research Article
Open Access

Downregulation of an Evolutionary Young miR-1290 in an iPSC-Derived Neural Stem Cell Model of Autism Spectrum Disorder

Dalia Moore,  Brittney M. Meays,  Lepakshe S. V. Madduri,  Farah Shahjin,  Subhash Chand,  Meng Niu,  Abrar Albahrani,  Chittibabu Guda,  Gurudutt Pendyala,  Howard S. Fox,  Sowmya V. Yelamanchili, 
  • First Published: 02 May 2019
Review Article
Open Access

Oligodendroglial Lineage Cells in Thyroid Hormone-Deprived Conditions

Min Joung Kim,  Steven Petratos, 
  • First Published: 30 April 2019
Research Article
Open Access

Metformin Delays Satellite Cell Activation and Maintains Quiescence

Theodora Pavlidou,  Milica Marinkovic,  Marco Rosina,  Claudia Fuoco,  Simone Vumbaca,  Cesare Gargioli,  Luisa Castagnoli,  Gianni Cesareni, 
  • First Published: 24 April 2019
Review Article
Open Access

Design Principles for Pluripotent Stem Cell-Derived Organoid Engineering

Teresa P. Silva,  João P. Cotovio,  Evguenia Bekman,  Maria Carmo-Fonseca,  Joaquim M. S. Cabral,  Tiago G. Fernandes, 
  • First Published: 18 April 2019
Research Article
Open Access

A Bioactive Cartilage Graft of IGF1-Transduced Adipose Mesenchymal Stem Cells Embedded in an Alginate/Bovine Cartilage Matrix Tridimensional Scaffold

Nidia K. Moncada-Saucedo,  Iván A. Marino-Martínez,  Jorge Lara-Arias,  Víktor J. Romero-Díaz,  Alberto Camacho,  J. A. Valdés-Franco,  Vanessa Pérez-Silos,  Alejandro García-Ruiz,  Hang Lin,  Rocky S. Tuan,  Rosalío Ramos-Payán,  M. Lara-Banda,  Rocio Ortiz-Lopez,  Augusto Rojas-Martinez,  Lizeth Fuentes-Mera, 
  • First Published: 18 April 2019
Research Article
Open Access

The Different Effects of IFN-β and IFN-γ on the Tumor-Suppressive Activity of Human Amniotic Fluid-Derived Mesenchymal Stem Cells

Jingchun Du,  Anqi Liu,  Rui Zhu,  Chengbo Zhou,  Heng Su,  Guie Xie,  Yingshan Deng,  Xia Xu, 
  • First Published: 15 April 2019
Review Article
Open Access

Challenges and Controversies in Human Mesenchymal Stem Cell Therapy

Barbara Lukomska,  Luiza Stanaszek,  Ewa Zuba-Surma,  Pawel Legosz,  Sylwia Sarzynska,  Katarzyna Drela, 
  • First Published: 09 April 2019
Research Article
Open Access

Preconditioning of Human Dental Pulp Stem Cells with Leukocyte- and Platelet-Rich Fibrin-Derived Factors Does Not Enhance Their Neuroregenerative Effect

Pascal Gervois,  Jessica Ratajczak,  Esther Wolfs,  Tim Vangansewinkel,  Yörg Dillen,  Greet Merckx,  Annelies Bronckaers,  Ivo Lambrichts, 
  • First Published: 08 April 2019
Research Article
Open Access

Metastable Reprogramming State of Single Transcription Factor-Derived Induced Hepatocyte-Like Cells

Seon In Hwang,  Tae Hwan Kwak,  Ji Hyun Kang,  Jonghun Kim,  Hyunseong Lee,  Kee-Pyo Kim,  Kinarm Ko,  Hans R. Schöler,  Dong Wook Han, 
  • First Published: 07 April 2019
Review Article
Open Access

Meta-Analysis and Evidence Base for the Efficacy of Autologous Bone Marrow Mesenchymal Stem Cells in Knee Cartilage Repair: Methodological Guidelines and Quality Assessment

Mohamed E. Awad,  Khaled A. Hussein,  Inas Helwa,  Mohamed F. Abdelsamid,  Alexandra Aguilar-Perez,  Ibrahim Mohsen,  Monte Hunter,  Mark W. Hamrick,  Carlos M. Isales,  Mohammed Elsalanty,  William D. Hill,  Sadanand Fulzele, 
  • First Published: 07 April 2019
Review Article
Open Access

Mitochondrial Dynamics: Biogenesis, Fission, Fusion, and Mitophagy in the Regulation of Stem Cell Behaviors

Wenyan Fu,  Yang Liu,  Hang Yin, 
  • First Published: 07 April 2019
Research Article
Open Access

Neuregulin-1 Fosters Supportive Interactions between Microglia and Neural Stem/Progenitor Cells

Ghazaleh M. Shahriary,  Hardeep Kataria,  Soheila Karimi-Abdolrezaee, 
  • First Published: 07 April 2019
Research Article
Open Access

Mesenchymal Progenitors Derived from Different Locations in Long Bones Display Diverse Characteristics

Weiguang Lu,  Bo Gao,  Jing Fan,  Pengzhen Cheng,  Yaqian Hu,  Qiang Jie,  Zhuojing Luo,  Liu Yang, 
  • First Published: 04 April 2019
Research Article
Open Access

Suppressing MicroRNA-30b by Estrogen Promotes Osteogenesis in Bone Marrow Mesenchymal Stem Cells

Guanqi Liu,  Yeming Lu,  Zhihui Mai,  Runheng Liu,  Zhuli Peng,  Lin Chen,  Zheng Chen,  Ruizhi Wang,  Hong Ai, 
  • First Published: 04 April 2019
Review Article
Open Access

Role of Toll-Like Receptors in Actuating Stem/Progenitor Cell Repair Mechanisms: Different Functions in Different Cells

Fabio Sallustio,  Claudia Curci,  Alessandra Stasi,  Giuseppe De Palma,  Chiara Divella,  Roberto Gramignoli,  Giuseppe Castellano,  Anna Gallone,  Loreto Gesualdo, 
  • First Published: 04 April 2019
Review Article
Open Access

Mechanism of Action of Icariin in Bone Marrow Mesenchymal Stem Cells

Aofei Yang,  Chaochao Yu,  Qilin Lu,  Hao Li,  Zhanghua Li,  Chengjian He, 
  • First Published: 04 April 2019
Research Article
Open Access

Study on the Dynamic Biological Characteristics of Human Bone Marrow Mesenchymal Stem Cell Senescence

Xiongbin Chen,  Lu Wang,  Jiyin Hou,  Jin Li,  Linbo Chen,  Jieyu Xia,  Ziling Wang,  Minghe Xiao,  Yaping Wang, 
  • First Published: 04 April 2019
Research Article
Open Access

An Investigation about Gene Modules Associated with hDPSC Differentiation for Adolescents

Wenjing Xu,  Jianqiang Li,  Juan Li,  Ji-Jiang Yang,  Qing Wang,  Bo Liu,  Weiliang Qiu, 
  • First Published: 04 April 2019
Review Article
Open Access

Phage-Based Artificial Niche: The Recent Progress and Future Opportunities in Stem Cell Therapy

Kshitiz Raj Shrestha,  So Young Yoo, 
  • First Published: 03 April 2019
Research Article
Open Access

Cancer Stem Cells from Tumor Cell Lines Activate the DNA Damage Response Pathway after Ionizing Radiation More Efficiently Than Noncancer Stem Cells

Heriberto Abraham Valencia-González,  Graciela Ruíz,  Elizabeth Ortiz-Sánchez,  Alejandro García-Carrancá, 
  • First Published: 03 April 2019
Research Article
Open Access

Purinergic Signaling Pathway in Human Olfactory Neuronal Precursor Cells

Héctor Solís-Chagoyán,  Edgar Flores-Soto,  Marcela Valdés-Tovar,  Montserrat G. Cercós,  Eduardo Calixto,  Luis M. Montaño,  Carlos Barajas-López,  Bettina Sommer,  Arnoldo Aquino-Gálvez,  Citlali Trueta,  Gloria A. Benítez-King, 
  • First Published: 02 April 2019
Review Article
Open Access

Stimuli-Responsive Graphene Nanohybrids for Biomedical Applications

Dinesh K. Patel,  Yu-Ri Seo,  Ki-Taek Lim, 
  • First Published: 02 April 2019
Research Article
Open Access

In Vitro Cultivation of Limbal Epithelial Stem Cells on Surface-Modified Crosslinked Collagen Scaffolds

Michel Haagdorens,  Vytautas Cėpla,  Eline Melsbach,  Laura Koivusalo,  Heli Skottman,  May Griffith,  Ramūnas Valiokas,  Nadia Zakaria,  Isabel Pintelon,  Marie-José Tassignon, 
  • First Published: 01 April 2019
Research Article
Open Access

Neuronal Transdifferentiation Potential of Human Mesenchymal Stem Cells from Neonatal and Adult Sources by a Small Molecule Cocktail

Lorena V. Cortés-Medina,  Herminia Pasantes-Morales,  Alejandro Aguilera-Castrejon,  Arturo Picones,  Cesar O. Lara-Figueroa,  Enoch Luis,  Juan Jose Montesinos,  Victor A. Cortés-Morales,  M. P. De la Rosa Ruiz,  Erika Hernández-Estévez,  Laura C. Bonifaz,  Marco Antonio Alvarez-Perez,  Gerardo Ramos-Mandujano, 
  • First Published: 01 April 2019
Research Article
Open Access

A Noninvasive Imaging Toolbox Indicates Limited Therapeutic Potential of Conditionally Activated Macrophages in a Mouse Model of Multiple Organ Dysfunction

Jack Sharkey,  Lorenzo Ressel,  Nathalie Brillant,  Lauren Scarfe,  Bettina Wilm,  B. Kevin Park,  Patricia Murray, 
  • First Published: 01 April 2019
Research Article
Open Access

Induced Pluripotent Stem Cell Derivation and Ex Vivo Gene Correction Using a Mucopolysaccharidosis Type 1 Disease Mouse Model

Toshio Miki,  Ludivina Vazquez,  Lisa Yanuaria,  Omar Lopez,  Irving M. Garcia,  Kazuo Ohashi,  Natalie S. Rodriguez, 
  • First Published: 01 April 2019
Research Article
Open Access

Effect of YAP on an Immortalized Periodontal Ligament Stem Cell Line

Xiyan Chen,  Qi Wang,  Ke Gu,  Aonan Li,  Xucheng Fu,  Ying Wang,  Weiting Gu,  Yong Wen, 
  • First Published: 01 April 2019
Research Article
Open Access

A Potential Antitumor Effect of Dendritic Cells Fused with Cancer Stem Cells in Hepatocellular Carcinoma

Ye-Bin Pang,  Jian He,  Bi-Yu Cui,  Sheng Xu,  Xi-Lei Li,  Man-Ya Wu,  Rong Liang,  Yan Feng,  Xing Guo,  Xue-Hui Zhang,  Xiao-Ling Luo, 
  • First Published: 01 April 2019
Research Article
Open Access

Mobilization of Transplanted Bone Marrow Mesenchymal Stem Cells by Erythropoietin Facilitates the Reconstruction of Segmental Bone Defect

Jun Li,  Zeyu Huang,  Bohua Li,  Zhengdong Zhang,  Lei Liu, 
  • First Published: 01 April 2019
Research Article
Open Access

Acute Leukemia Induces Senescence and Impaired Osteogenic Differentiation in Mesenchymal Stem Cells Endowing Leukemic Cells with Functional Advantages

Ximena Bonilla,  Natalia-Del Pilar Vanegas,  Jean Paul Vernot, 
  • First Published: 01 April 2019
Review Article
Open Access

The Emerging Role of Mesenchymal Stem Cells in Vascular Calcification

Changming Xie,  Liu Ouyang,  Jie Chen,  Huanji Zhang,  Pei Luo,  Jingfeng Wang,  Hui Huang, 
  • First Published: 01 April 2019
Research Article
Open Access

Genome-Wide Mapping of Bivalent Histone Modifications in Hepatic Stem/Progenitor Cells

Kengo Kanayama,  Tetsuhiro Chiba,  Motohiko Oshima,  Hiroaki Kanzaki,  Shuhei Koide,  Atsunori Saraya,  Satoru Miyagi,  Naoya Mimura,  Yuko Kusakabe,  Tomoko Saito,  Sadahisa Ogasawara,  Eiichiro Suzuki,  Yoshihiko Ooka,  Hitoshi Maruyama,  Atsushi Iwama,  Naoya Kato, 
  • First Published: 01 April 2019
Research Article
Open Access

Expression of Potential Dermal Progenitor Cell Markers in the Tumour and Stroma of Skin Adnexal Malignant and Benign Tumours

Sven R. Quist,  Maximilian Eckardt,  André Kriesche,  Harald P. Gollnick, 
  • First Published: 01 April 2019
Research Article
Open Access

Improved Efficiency of Cardiomyocyte-Like Cell Differentiation from Rat Adipose Tissue-Derived Mesenchymal Stem Cells with a Directed Differentiation Protocol

Blanca Rebeca Ibarra-Ibarra,  Martha Franco,  Araceli Paez,  Elvira Varela López,  Felipe Massó, 
  • First Published: 01 April 2019
Research Article
Open Access

Structural and Mechanistic Bases of Nuclear Calcium Signaling in Human Pluripotent Stem Cell-Derived Ventricular Cardiomyocytes

Sen Li,  Wendy Keung,  Heping Cheng,  Ronald A. Li, 
  • First Published: 01 April 2019
Corrigendum
Open Access

Corrigendum to “Mouse Mesenchymal Progenitor Cells Expressing Adipogenic and Osteogenic Transcription Factors Suppress the Macrophage Inflammatory Response”

Natalie Fernandez,  Heather Renna,  Lauren McHugh,  Katie Mazalkova,  William Crugnola,  Jodi F. Evans, 
  • First Published: 01 April 2019

Research Article
Open Access

In Vitro Effect of Estradiol and Progesterone on Ovine Amniotic Epithelial Cells

Annunziata Mauro,  Hashimita Sanyal,  Angelo Canciello,  Paolo Berardinelli,  Valentina Russo,  Nicola Bernabò,  Luca Valbonetti,  Barbara Barboni, 
  • First Published: 27 March 2019
Research Article
Open Access

The Conditioned Medium of Calcined Tooth Powder Promotes the Osteogenic and Odontogenic Differentiation of Human Dental Pulp Stem Cells via MAPK Signaling Pathways

Jintao Wu,  Na Li,  Yuan Fan,  Yanqiu Wang,  Yongchun Gu,  Zehan Li,  Yin Pan,  Gobin Romila,  Zuomin Zhou,  Jinhua Yu, 
  • First Published: 19 March 2019
Review Article
Open Access

Intestinal Organoids as a Novel Complementary Model to Dissect Inflammatory Bowel Disease

L. Schulte,  M. Hohwieler,  M. Müller,  J. Klaus, 
  • First Published: 19 March 2019
Research Article
Open Access

Exosomes from Human Umbilical Cord Mesenchymal Stem Cells Reduce Damage from Oxidative Stress and the Epithelial-Mesenchymal Transition in Renal Epithelial Cells Exposed to Oxalate and Calcium Oxalate Monohydrate

Dian Li,  Dan Zhang,  Bo Tang,  Yue Zhou,  Wenhao Guo,  Qing Kang,  Zhang Wang,  Lianju Shen,  Guanghui Wei,  Dawei He, 
  • First Published: 19 March 2019
Research Article
Open Access

Cancer Stem Cell Marker Endoglin (CD105) Induces Epithelial Mesenchymal Transition (EMT) but Not Metastasis in Clear Cell Renal Cell Carcinoma

Junhui Hu,  Wei Guan,  Libin Yan,  Zhangqun Ye,  Lily Wu,  Hua Xu, 
  • First Published: 19 March 2019
Research Article
Open Access

Rat Hippocampal Neural Stem Cell Modulation Using PDGF, VEGF, PDGF/VEGF, and BDNF

Neus Gomila Pelegri,  Catherine A. Gorrie,  Jerran Santos, 
  • First Published: 18 March 2019
Research Article
Open Access

Equine Adipose-Derived Mesenchymal Stromal Cells Release Extracellular Vesicles Enclosing Different Subsets of Small RNAs

Stefano Capomaccio,  Katia Cappelli,  Cinzia Bazzucchi,  Mauro Coletti,  Rodolfo Gialletti,  Franco Moriconi,  Fabrizio Passamonti,  Marco Pepe,  Stefano Petrini,  Samanta Mecocci,  Maurizio Silvestrelli,  Luisa Pascucci, 
  • First Published: 18 March 2019
Research Article
Open Access

Effects of Delta-Like Noncanonical Notch Ligand 1 Expression of Human Fetal Liver Hepatoblasts on Hematopoietic Progenitors

Jörg C. Gerlach,  Robert L. Thompson,  Bruno Gridelli,  Eva Schmelzer, 
  • First Published: 18 March 2019
Research Article
Open Access

Metformin Inhibits the Expression of Biomarkers of Fibrosis of EPCs In Vitro

Fei Han,  Jie Shu,  Shunjun Wang,  Can-e Tang,  Fanyan Luo, 
  • First Published: 18 March 2019
Research Article
Open Access

Isolation and Characterization of an Adult Stem Cell Population from Human Epidural Fat

Nedaa Al-Jezani,  Roger Cho,  Anand O. Masson,  Brian Lenehan,  Roman Krawetz,  Frank G. Lyons, 
  • First Published: 17 March 2019
Research Article
Open Access

Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibit Endometrial Cancer Cell Proliferation and Migration through Delivery of Exogenous miR-302a

Xin Li,  Li li Liu,  Ju lei Yao,  Kai Wang,  Hao Ai, 
  • First Published: 14 March 2019
Research Article
Open Access

Noninvasive Monitoring of Allogeneic Stem Cell Delivery with Dual-Modality Imaging-Visible Microcapsules in a Rabbit Model of Peripheral Arterial Disease

Yingli Fu,  Clifford R. Weiss,  Dorota A. Kedziorek,  Yibin Xie,  Ellen Tully,  Steven M. Shea,  Meiyappan Solaiyappan,  Tina Ehtiati,  Kathleen Gabrielson,  Frank H. Wacker,  Jeff W. M. Bulte,  Dara L. Kraitchman, 
  • First Published: 14 March 2019
Research Article
Open Access

Identification and Characterization of the OCT4 Upstream Regulatory Region in Sus scrofa

Seung-Hun Kim,  Kwang-Hwan Choi,  Dong-Kyung Lee,  Mingyun Lee,  Jae Yeon Hwang,  Chang-Kyu Lee, 
  • First Published: 12 March 2019
Research Article
Open Access

Notch Inhibition Promotes Differentiation of Liver Progenitor Cells into Hepatocytes via sox9b Repression in Zebrafish

Jacquelyn O. Russell,  Sungjin Ko,  Satdarshan P. Monga,  Donghun Shin, 
  • First Published: 12 March 2019
Corrigendum
Open Access

Corrigendum to “Impact and Challenges of Mesenchymal Stem Cells in Medicine: An Overview of the Current Knowledge”

Farid Menaa,  Somayeh Shahrokhi,  V. Prasad Shastri, 
  • First Published: 10 March 2019

Review Article
Open Access

Mesenchymal Stem Cells: A Potential Therapeutic Approach for Amyotrophic Lateral Sclerosis?

Agnese Gugliandolo,  Placido Bramanti,  Emanuela Mazzon, 
  • First Published: 10 March 2019
Review Article
Open Access

One-Carbon Metabolism Links Nutrition Intake to Embryonic Development via Epigenetic Mechanisms

Si Wu,  Jun Zhang,  Feifei Li,  Wei Du,  Xin Zhou,  Mian Wan,  Yi Fan,  Xin Xu,  Xuedong Zhou,  Liwei Zheng,  Yachuan Zhou, 
  • First Published: 10 March 2019
Research Article
Open Access

Potential Research Tool of Stem Cells from Human Exfoliated Deciduous Teeth: Lentiviral Bmi-1 Immortalization with EGFP Marker

Siqi Yao,  Lingping Tan,  Huan Chen,  Xiaojun Huang,  Wei Zhao,  Yan Wang, 
  • First Published: 10 March 2019
Corrigendum
Open Access

Corrigendum to “Comparison of the Proliferation and Differentiation Potential of Human Urine-, Placenta Decidua Basalis-, and Bone Marrow-Derived Stem Cells”

Chengguang Wu,  Long Chen,  Yi-zhou Huang,  Yongcan Huang,  Ornella Parolini,  Qing Zhong,  Xiaobin Tian,  Li Deng, 
  • First Published: 10 March 2019

Research Article
Open Access

Ex Vivo Expansion of Murine MSC Impairs Transcription Factor-Induced Differentiation into Pancreatic β-Cells

Dario Gerace,  Rosetta Martiniello-Wilks,  Rosaline Habib,  Binhai Ren,  Najah Therese Nassif,  Bronwyn Anne O’Brien,  Ann Margaret Simpson, 
  • First Published: 10 March 2019
Editorial
Open Access

Current Status and Perspectives of Human Mesenchymal Stem Cell Therapy

Jane Ru Choi,  Kar Wey Yong,  Hui Yin Nam, 
  • First Published: 07 March 2019
Research Article
Open Access

Cord Blood Banking: Antenatal Care Provider’s Roles and Responsibilities

Vishal Gupta,  Lipisha Agarwal,  Priya Ballal,  Deeksha Pandey, 
  • First Published: 07 March 2019
Research Article
Open Access

The Genetic Landscape of Human Glioblastoma and Matched Primary Cancer Stem Cells Reveals Intratumour Similarity and Intertumour Heterogeneity

Chiara Pesenti,  Stefania Elena Navone,  Laura Guarnaccia,  Andrea Terrasi,  Jole Costanza,  Rosamaria Silipigni,  Silvana Guarneri,  Nicola Fusco,  Laura Fontana,  Marco Locatelli,  Paolo Rampini,  Rolando Campanella,  Silvia Tabano,  Monica Miozzo,  Giovanni Marfia, 
  • First Published: 07 March 2019
Research Article
Open Access

Morphological and Molecular Analysis of In Vitro Tubular Structures from Bovine Yolk Sac-Derived MSCs

Celina A. F. Mançanares,  Vanessa Cristina de Oliveira,  Lilian J. Oliveira,  Maria A. Miglino,  Flávio Vieira Meirelles,  Carlos E. Ambrósio, 
  • First Published: 06 March 2019
Editorial
Open Access

Mesenchymal Stem Cells: Characteristics, Function, and Application

Zhongjun Li,  Xingbin Hu,  Jiang F. Zhong, 
  • First Published: 06 March 2019
Research Article
Open Access

Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients

Tadashi Takaki,  Azusa Inagaki,  Kazuhisa Chonabayashi,  Keiji Inoue,  Kenji Miki,  Seiko Ohno,  Takeru Makiyama,  Minoru Horie,  Yoshinori Yoshida, 
  • First Published: 06 March 2019

Review Article
Open Access

Experimental Strategies of Mesenchymal Stem Cell Propagation: Adverse Events and Potential Risk of Functional Changes

Katarzyna Drela,  Luiza Stanaszek,  Adam Nowakowski,  Zuzanna Kuczynska,  Barbara Lukomska, 
  • First Published: 06 March 2019
Research Article
Open Access

Different Responses to Drug Safety Screening Targets between Human Neonatal and Infantile Heart Tissue and Cardiac Bodies Derived from Human-Induced Pluripotent Stem Cells

Jan Trieschmann,  Moritz Haustein,  Annette Köster,  Jürgen Hescheler,  Konrad Brockmeier,  Gerardus Bennink,  Tobias Hannes, 
  • First Published: 06 March 2019
Editorial
Open Access

Stem Cells in Cancer Progression and Therapy

Hua Tan,  Weijun Su,  Xing-Ding Zhang, 
  • First Published: 05 March 2019
Research Article
Open Access

Potential Role of the Resident Mesenchymal Stem-Like Cells in Renal Fibrogenesis after Ureteral Obstruction

Yong-Hua Peng,  Jie Xiao,  Chen Yan,  Lan Luo,  Tao-Sheng Li, 
  • First Published: 05 March 2019
Corrigendum
Open Access

Corrigendum to “Immune Suppressive Effects of Tonsil-Derived Mesenchymal Stem Cells on Mouse Bone-Marrow-Derived Dendritic Cells”

Minhwa Park,  Yu-Hee Kim,  Jung-Hwa Ryu,  So-Youn Woo,  Kyung-Ha Ryu, 
  • First Published: 05 March 2019

Research Article
Open Access

Phenotypic Analysis of BrdU Label-Retaining Cells during the Maturation of Conducting Airway Epithelium in a Porcine Lung

Yuanyuan Jia,  Xuehong You,  Ningxia Ma,  Hui Li,  Guopan Liu,  Ying Wang,  Jing Xue,  Juan Shi,  Jun Wei,  Yong Li,  Jiali Yang,  Xiaoming Liu, 
  • First Published: 27 February 2019
Review Article
Open Access

Stem Cell-Derived Extracellular Vesicles as Immunomodulatory Therapeutics

Yoojin Seo,  Hyung-Sik Kim,  In-Sun Hong, 
  • First Published: 26 February 2019
Research Article
Open Access

NOTCH Signaling Is Activated through Mechanical Strain in Human Bone Marrow-Derived Mesenchymal Stromal Cells

Fani Ziouti,  Regina Ebert,  Maximilian Rummler,  Melanie Krug,  Sigrid Müller-Deubert,  Martin Lüdemann,  Franz Jakob,  Bettina M. Willie,  Franziska Jundt, 
  • First Published: 26 February 2019
Research Article
Open Access

Effect of Chitosan Nanoparticle-Loaded Thymus serpyllum on Hydrogen Peroxide-Induced Bone Marrow Stromal Cell Damage

Salma Baig,  Ainnul Hamidah Syahadah Azizan,  Hanumantha Rao Balaji Raghavendran,  Elango Natarajan,  Sangeetha Naveen,  Malliga Raman Murali,  Hui Yin Nam,  Tunku Kamarul, 
  • First Published: 26 February 2019
Research Article
Open Access

Epsins Regulate Mouse Embryonic Stem Cell Exit from Pluripotency and Neural Commitment by Controlling Notch Activation

Marina Cardano,  Jacopo Zasso,  Luca Ruggiero,  Giuseppina Di Giacomo,  Matteo Marcatili,  Ottavio Cremona,  Luciano Conti, 
  • First Published: 25 February 2019
Review Article
Open Access

Pancreatic Progenitors and Organoids as a Prerequisite to Model Pancreatic Diseases and Cancer

Meike Hohwieler,  Martin Müller,  Pierre-Olivier Frappart,  Sandra Heller, 
  • First Published: 25 February 2019
Research Article
Open Access

The Biguanides Metformin and Buformin in Combination with 2-Deoxy-glucose or WZB-117 Inhibit the Viability of Highly Resistant Human Lung Cancer Cells

Juan Sebastian Yakisich,  Neelam Azad,  Vivek Kaushik,  Anand K. V. Iyer, 
  • First Published: 21 February 2019
Research Article
Open Access

Uniaxial Cyclic Tensile Stretching at 8% Strain Exclusively Promotes Tenogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stromal Cells

Hui Yin Nam,  Belinda Pingguan-Murphy,  Azlina Amir Abbas,  Azhar Mahmood Merican,  Tunku Kamarul, 
  • First Published: 21 February 2019
Research Article
Open Access

Characterization and Optimization of the Seeding Process of Adipose Stem Cells on the Polycaprolactone Scaffolds

Agata Kurzyk,  Barbara Ostrowska,  Wojciech Święszkowski,  Zygmunt Pojda, 
  • First Published: 20 February 2019
Research Article
Open Access

Long-Lasting Anti-Inflammatory Activity of Human Microfragmented Adipose Tissue

Sara Nava,  Valeria Sordi,  Luisa Pascucci,  Carlo Tremolada,  Emilio Ciusani,  Offer Zeira,  Moris Cadei,  Gianni Soldati,  Augusto Pessina,  Eugenio Parati,  Mark Slevin,  Giulio Alessandri, 
  • First Published: 19 February 2019
Review Article
Open Access

Remodelling and Improvements in Organoid Technology to Study Liver Carcinogenesis in a Dish

Umesh Tharehalli,  Michael Svinarenko,  André Lechel, 
  • First Published: 19 February 2019
Research Article
Open Access

Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis

Roman G. Vasyliev,  Olga S. Gubar,  Inna M. Gordiienko,  Larisa S. Litvinova,  Anzhela E. Rodnichenko,  Valeria V. Shupletsova,  Alona V. Zlatska,  Kristina A. Yurova,  Natalia M. Todosenko,  Veronika E. Khadzhynova,  Mariia V. Shulha,  Svitlana N. Novikova,  Dmytro O. Zubov, 
  • First Published: 19 February 2019
Research Article
Open Access

Comparison of Immunosuppressive and Angiogenic Properties of Human Amnion-Derived Mesenchymal Stem Cells between 2D and 3D Culture Systems

Vitale Miceli,  Mariangela Pampalone,  Serena Vella,  Anna Paola Carreca,  Giandomenico Amico,  Pier Giulio Conaldi, 
  • First Published: 18 February 2019
Research Article
Open Access

Obesity-Induced Methylation of Osteopontin Contributes to Adipogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells

Min Tang,  Rui Chen,  Hao Wang,  Guowei Sun,  Fan Yin,  Beibei Liang,  Yang Yang,  Gaowa Sharen,  Huafeng Wei,  Xuyu Zhou,  Gang Huang,  Jian Zhao, 
  • First Published: 17 February 2019
Research Article
Open Access

Insulin-Like Growth Factor Binding Protein-6 Promotes the Differentiation of Placental Mesenchymal Stem Cells into Skeletal Muscle Independent of Insulin-Like Growth Factor Receptor-1 and Insulin Receptor

Doaa Aboalola,  Victor K. M. Han, 
  • First Published: 17 February 2019
Research Article
Open Access

Differentiation of Stem Cells from Human Exfoliated Deciduous Teeth into Retinal Photoreceptor-Like Cells and Their Sustainability In Vivo

Xiaoxia Li,  Jing Xie,  Yue Zhai,  Tengjiaozi Fang,  Nanquan Rao,  Shuang Hu,  Liping Yang,  Yuming Zhao,  Yixiang Wang,  Lihong Ge, 
  • First Published: 14 February 2019
Review Article
Open Access

Unchain My Heart: Integrins at the Basis of iPSC Cardiomyocyte Differentiation

Rosaria Santoro,  Gianluca Lorenzo Perrucci,  Aoife Gowran,  Giulio Pompilio, 
  • First Published: 13 February 2019
Research Article
Open Access

Influence of Adipose Tissue-Derived Stem Cells on the Burn Wound Healing Process

Claudio Luciano Franck,  Alexandra Cristina Senegaglia,  Lidiane Maria Boldrini Leite,  Sérgio Adriane Bezerra de Moura,  Nathália Forti Francisco,  Jurandir Marcondes Ribas Filho, 
  • First Published: 11 February 2019
Research Article
Open Access

Coculture of hWJMSCs and pACs in Oriented Scaffold Enhances Hyaline Cartilage Regeneration In Vitro

Yu Zhang,  Shuyun Liu,  Weimin Guo,  Chunxiang Hao,  Mingjie Wang,  Xu Li,  Xueliang Zhang,  Mingxue Chen,  Zehao Wang,  Xiang Sui,  Jiang Peng,  Yu Wang,  Shibi Lu,  Quanyi Guo, 
  • First Published: 07 February 2019
Research Article
Open Access

α2-HS Glycoprotein in Plasma Extracellular Vesicles Inhibits the Osteogenic Differentiation of Human Mesenchymal Stromal Cells In Vitro

Xiaohua Wu,  Mengjun Ma,  Peng Wang,  Zhongyu Xie,  Shan Wang,  Hongjun Su,  Wen Deng,  Pei Feng,  Chunyan Su,  Jiewen Yang,  Jinteng Li,  Su’an Tang,  Yanfeng Wu,  Huiyong Shen, 
  • First Published: 07 February 2019
Review Article
Open Access

Mitochondrial Role in Stemness and Differentiation of Hematopoietic Stem Cells

Luena Papa,  Mansour Djedaini,  Ronald Hoffman, 
  • First Published: 06 February 2019
Research Article
Open Access

Scalable Culture Strategies for the Expansion of Patient-Derived Cancer Stem Cell Lines

Ana Teresa Serra,  Margarida Serra,  Ana Carina Silva,  Tamara Brckalo,  Anita Seshire,  Catarina Brito,  Michael Wolf,  Paula M. Alves, 
  • First Published: 06 February 2019
Research Article
Open Access

CXCR4-Overexpressing Umbilical Cord Mesenchymal Stem Cells Enhance Protection against Radiation-Induced Lung Injury

Chunyang Zhang,  Yan Zhu,  Ji Wang,  Lisheng Hou,  Wei Li,  Huaijie An, 
  • First Published: 05 February 2019
Research Article
Open Access

Characteristics of Intestinal Microecology during Mesenchymal Stem Cell-Based Therapy for Mouse Acute Liver Injury

Xiaotian Dong,  Xudong Feng,  Jingqi Liu,  Yanping Xu,  Qiaoling Pan,  Zongxin Ling,  Jiong Yu,  Jinfeng Yang,  Lanjuan Li,  Hongcui Cao, 
  • First Published: 05 February 2019
Research Article
Open Access

Developing a Novel and Convenient Model for Investigating Sweat Gland Morphogenesis from Epidermal Stem Cells

Tian Hu,  Yongde Xu,  Bin Yao,  Xiaobing Fu,  Sha Huang, 
  • First Published: 04 February 2019
Clinical Study
Open Access

Combination Treatments of Plasma Exchange and Umbilical Cord-Derived Mesenchymal Stem Cell Transplantation for Patients with Hepatitis B Virus-Related Acute-on-Chronic Liver Failure: A Clinical Trial in China

Wen-xiong Xu,  Hong-liang He,  Shun-wen Pan,  Yuan-li Chen,  Mei-ling Zhang,  Shu Zhu,  Zhi-liang Gao,  Liang Peng,  Jian-guo Li, 
  • First Published: 04 February 2019
Research Article
Open Access

The Role of RNA Polymerase II Contiguity and Long-Range Interactions in the Regulation of Gene Expression in Human Pluripotent Stem Cells

Livia Eiselleova,  Viktor Lukjanov,  Simon Farkas,  David Svoboda,  Karel Stepka,  Irena Koutna, 
  • First Published: 03 February 2019
Research Article
Open Access

Mesenchymal Stem Cells Coated by the Extracellular Matrix Promote Wound Healing in Diabetic Rats

Linhao Wang,  Fang Wang,  Liling Zhao,  Wenjun Yang,  Xinxing Wan,  Chun Yue,  Zhaohui Mo, 
  • First Published: 28 January 2019

Research Article
Open Access

Wnt-GSK3β/β-Catenin Regulates the Differentiation of Dental Pulp Stem Cells into Bladder Smooth Muscle Cells

Wenkai Jiang,  Diya Wang,  Amr Alraies,  Qian Liu,  Bangfu Zhu,  Alastair J. Sloan,  Longxing Ni,  Bing Song, 
  • First Published: 28 January 2019
Review Article
Open Access

Intestinal Epithelial Organoids as Tools to Study Epigenetics in Gut Health and Disease

Judith Kraiczy,  Matthias Zilbauer, 
  • First Published: 27 January 2019
Research Article
Open Access

Angiogenic Properties of Menstrual Stem Cells Are Impaired in Women with a History of Preeclampsia

Manuel Varas-Godoy,  Stephanie Acuña-Gallardo,  Sebastian Venegas-Duarte,  Charlotte Hill,  Albano Caceres-Verschae,  Ornella Realini,  Lara J. Monteiro,  Gabriela Zavala,  Maroun Khoury,  Roberto Romero,  Gregory Rice,  Sebastian E. Illanes, 
  • First Published: 27 January 2019
Review Article
Open Access

Cell Therapy for Retinal Dystrophies: From Cell Suspension Formulation to Complex Retinal Tissue Bioengineering

Karim Ben M’Barek,  Christelle Monville, 
  • First Published: 23 January 2019
Research Article
Open Access

Fine Tuning of Hepatocyte Differentiation from Human Embryonic Stem Cells: Growth Factor vs. Small Molecule-Based Approaches

Divya S. Varghese,  Thilina Thejinda Alawathugoda,  Suraiya A. Ansari, 
  • First Published: 22 January 2019
Research Article
Open Access

Laminin as a Potent Substrate for Large-Scale Expansion of Human Induced Pluripotent Stem Cells in a Closed Cell Expansion System

Fernanda C. Paccola Mesquita,  Camila Hochman-Mendez,  Jacquelynn Morrissey,  Luiz C. Sampaio,  Doris A. Taylor, 
  • First Published: 22 January 2019
Research Article
Open Access

Human Embryonic Stem Cells Acquire Responsiveness to TRAIL upon Exposure to Cisplatin

Lucie Pešková,  Vladimír Vinarský,  Tomáš Bárta,  Aleš Hampl, 
  • First Published: 21 January 2019
Review Article
Open Access

Digit Tip Injuries: Current Treatment and Future Regenerative Paradigms

Travis J. Miller,  Peter L. Deptula,  Gregory M. Buncke,  Zeshaan N. Maan, 
  • First Published: 21 January 2019
Research Article
Open Access

Clinically Relevant Solution for the Hypothermic Storage and Transportation of Human Multipotent Mesenchymal Stromal Cells

Yuriy Petrenko,  Milada Chudickova,  Irena Vackova,  Tomas Groh,  Eliska Kosnarova,  Jitka Cejkova,  Karolina Turnovcova,  Alexander Petrenko,  Eva Sykova,  Sarka Kubinova, 
  • First Published: 20 January 2019
Research Article
Open Access

Comparative AAV-eGFP Transgene Expression Using Vector Serotypes 1–9, 7m8, and 8b in Human Pluripotent Stem Cells, RPEs, and Human and Rat Cortical Neurons

Thu T. Duong,  James Lim,  Vidyullatha Vasireddy,  Tyler Papp,  Hung Nguyen,  Lanfranco Leo,  Jieyan Pan,  Shangzhen Zhou,  H. Isaac Chen,  Jean Bennett,  Jason A. Mills, 
  • First Published: 17 January 2019
Research Article
Open Access

The Late Osteoblast/Preosteocyte Cell Line MLO-A5 Displays Mesenchymal Lineage Plasticity In Vitro and In Vivo

Dongqing Yang,  Stan Gronthos,  Sandra Isenmann,  Howard A. Morris,  Gerald J. Atkins, 
  • First Published: 17 January 2019
Research Article
Open Access

Osteoarthritic Synovial Fluid Modulates Cell Phenotype and Metabolic Behavior In Vitro

Eduardo Branco de Sousa,  Gilson Costa dos Santos Junior,  Ramon Pinheiro Aguiar,  Rafaela da Costa Sartore,  Ana Carolina Leal de Oliveira,  Fabio Ceneviva Lacerda Almeida,  Vivaldo Moura Neto,  Diego Pinheiro Aguiar, 
  • First Published: 15 January 2019
Research Article
Open Access

Serum-Free Manufacturing of Mesenchymal Stem Cell Tissue Rings Using Human-Induced Pluripotent Stem Cells

Tackla S. Winston,  Kantaphon Suddhapas,  Chenyan Wang,  Rafael Ramos,  Pranav Soman,  Zhen Ma, 
  • First Published: 15 January 2019
Review Article
Open Access

Head to Knee: Cranial Neural Crest-Derived Cells as Promising Candidates for Human Cartilage Repair

Ihsène Taïhi,  Ali Nassif,  Juliane Isaac,  Benjamin Philippe Fournier,  François Ferré, 
  • First Published: 15 January 2019
Research Article
Open Access

Oral Plaque from Type 2 Diabetic Patients Reduces the Clonogenic Capacity of Dental Pulp-Derived Mesenchymal Stem Cells

Antonella Bordin,  Francesca Pagano,  Eleonora Scaccia,  Matteo Saccucci,  Iole Vozza,  Noemi Incerti,  Antonella Polimeni,  Elena Cavarretta,  Isotta Chimenti,  Elena De Falco, 
  • First Published: 14 January 2019
Review Article
Open Access

Aldehyde Dehydrogenases: Not Just Markers, but Functional Regulators of Stem Cells

Giuseppe Vassalli, 
  • First Published: 13 January 2019
Research Article
Open Access

Titanium Surface Properties Influence the Biological Activity and FasL Expression of Craniofacial Stromal Cells

Enrico Conserva,  Alessandra Pisciotta,  Francesco Borghi,  Milena Nasi,  Simone Pecorini,  Laura Bertoni,  Anto de Pol,  Ugo Consolo,  Gianluca Carnevale, 
  • First Published: 13 January 2019
Review Article
Open Access

Mesenchymal Stem Cells in Renal Fibrosis: The Flame of Cytotherapy

Quan Zhuang,  Ruoyu Ma,  Yanshuang Yin,  Tianhao Lan,  Meng Yu,  Yingzi Ming, 
  • First Published: 13 January 2019
Research Article
Open Access

Environmental Benzopyrene Attenuates Stemness of Placenta-Derived Mesenchymal Stem Cells via Aryl Hydrocarbon Receptor

June Seok Heo,  Ja-Yun Lim,  Sangshin Pyo,  Dae Wui Yoon,  Dongsook Lee,  Wen Xiu Ren,  Seung Gwan Lee,  Gi Jin Kim,  Jinkwan Kim, 
  • First Published: 13 January 2019
Review Article
Open Access

Immunomodulatory Functions of Mesenchymal Stem Cells in Tissue Engineering

Haojiang Li,  Shi Shen,  Haitao Fu,  Zhenyong Wang,  Xu Li,  Xiang Sui,  Mei Yuan,  Shuyun Liu,  Guiqin Wang,  Quanyi Guo, 
  • First Published: 13 January 2019
Research Article
Open Access

A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of Primary Cultured Cells and Subcultured Cells Using Mouse Adipose-Derived Mesenchymal Stem Cells

Yoshiki Nakashima,  Saifun Nahar,  Chika Miyagi-Shiohira,  Takao Kinjo,  Naoya Kobayashi,  Issei Saitoh,  Masami Watanabe,  Jiro Fujita,  Hirofumi Noguchi, 
  • First Published: 10 January 2019
Research Article
Open Access

Geranylgeraniol (GGOH) as a Mevalonate Pathway Activator in the Rescue of Bone Cells Treated with Zoledronic Acid: An In Vitro Study

Riham M. Fliefel,  Saleh A. Entekhabi,  Michael Ehrenfeld,  Sven Otto, 
  • First Published: 09 January 2019
Research Article
Open Access

Amifostine Suppresses the Side Effects of Radiation on BMSCs by Promoting Cell Proliferation and Reducing ROS Production

Bo Huang,  Tao He,  Qianqian Yao,  Liang Zhang,  Yang Yao,  Hua Tang,  Ping Gong, 
  • First Published: 09 January 2019
Review Article
Open Access

Stem Cells and Cellular Origins of Mammary Gland: Updates in Rationale, Controversies, and Cancer Relevance

Jiaojiao Zhou,  Qishan Chen,  Yiheng Zou,  Shu Zheng,  Yiding Chen, 
  • First Published: 08 January 2019
Review Article
Open Access

Multiscale Stem Cell Technologies for Osteonecrosis of the Femoral Head

Yi Wang,  Xibo Ma,  Wei Chai,  Jie Tian, 
  • First Published: 08 January 2019
Review Article
Open Access

Notch3 Targeting: A Novel Weapon against Ovarian Cancer Stem Cells

Simona Ceccarelli,  Francesca Megiorni,  Diana Bellavia,  Cinzia Marchese,  Isabella Screpanti,  Saula Checquolo, 
  • First Published: 06 January 2019
Editorial
Open Access

Stem/Progenitor Cells in Cardiopulmonary Health, Disease, and Treatment

Fatemeh Sharifpanah,  Hossein A. Ghofrani,  Suk Ying Tsang,  Heinrich Sauer, 
  • First Published: 06 January 2019
Research Article
Open Access

Skeletal Muscle Resident Progenitor Cells Coexpress Mesenchymal and Myogenic Markers and Are Not Affected by Chronic Heart Failure-Induced Dysregulations

R. I. Dmitrieva,  T. A. Lelyavina,  M. Y. Komarova,  V. L. Galenko,  O. A. Ivanova,  P. A. Tikanova,  N. V. Khromova,  A. S. Golovkin,  M. A. Bortsova,  A. Sergushichev,  M. Yu. Sitnikova,  A. A. Kostareva, 
  • First Published: 03 January 2019
Research Article
Open Access

Pretreatment with G-CSF Could Enhance the Antifibrotic Effect of BM-MSCs on Pulmonary Fibrosis

Feiyan Zhao,  Wei Liu,  Shaojie Yue,  Lei Yang,  Qingzhong Hua,  Yan Zhou,  Haipeng Cheng,  Ziqiang Luo,  Siyuan Tang, 
  • First Published: 03 January 2019