Volume 2019, Issue 1 7274057
Research Article
Open Access

A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of Primary Cultured Cells and Subcultured Cells Using Mouse Adipose-Derived Mesenchymal Stem Cells

Yoshiki Nakashima

Yoshiki Nakashima

Department of Regenerative Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa 903-0215, Japan u-ryukyu.ac.jp

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Saifun Nahar

Saifun Nahar

Department of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus, Okinawa 903-0215, Japan u-ryukyu.ac.jp

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Chika Miyagi-Shiohira

Chika Miyagi-Shiohira

Department of Regenerative Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa 903-0215, Japan u-ryukyu.ac.jp

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Takao Kinjo

Takao Kinjo

Department of Basic Laboratory Sciences, School of Health Sciences in Faculty of Medicine, University of the Ryukyus, Okinawa 903-0215, Japan u-ryukyu.ac.jp

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Naoya Kobayashi

Naoya Kobayashi

Okayama Saidaiji Hospital, Okayama 704-8192, Japan saidaiji-hp.or.jp

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Issei Saitoh

Issei Saitoh

Division of Pediatric Dentistry, Graduate School of Medical and Dental Science, Niigata University, Niigata 951-8514, Japan niigata-u.ac.jp

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Masami Watanabe

Masami Watanabe

Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan okayama-u.ac.jp

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Jiro Fujita

Jiro Fujita

Department of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus, Okinawa 903-0215, Japan u-ryukyu.ac.jp

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Hirofumi Noguchi

Corresponding Author

Hirofumi Noguchi

Department of Regenerative Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa 903-0215, Japan u-ryukyu.ac.jp

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First published: 10 January 2019
Citations: 1
Academic Editor: Katia Mareschi

Abstract

Adipose-derived mesenchymal stem cells (MSC-ATs) are representative cell sources for cell therapy. However, how cell stress resulting from passage influences the MSC-AT protein expression has been unclear. In this study, a protein expression analysis was performed by liquid chromatography with tandem mass spectrometry (LC-MS/MS) using mouse primary cultured cells (P0) and cells passaged three times (P3) as samples. A total of 256 proteins were classified as cellular process-related proteins, while 179 were classified as metabolic process-related proteins in P0. These were considered to be adaptive responses of the cells to an in vitro environment. However, seven proteins of growth were identified (Csf1, App, Adam15, Alcam, Tbl1xr1, Ninj1, and Sbds) in P0. In addition, four proteins of antioxidant activity were also identified (Srxn1, Txndc17, Fam213b, and Apoe) in P0. We identified 1139 proteins expressed in both P0 and P3 cells that had their expression decreased to 69.4% in P3 cells compared with P0 cells, but 1139 proteins are very likely proteins that are derived from MSC-AT. The function of MSC-ATs was maintained after three passages. However, the LC-MS/MS analysis data showed that the protein expression was degraded after three passages. MSC-ATs retained about 70% of their protein expression ability in P3 cells.

1. Introduction

Mesenchymal stromal stem cells (MSCs) are considered to have the ability to differentiate into mesenchymal cells, such as osteoblasts, adipocytes, muscle cells, and chondrocytes [1, 2]. These cells are also expected to have an immunosuppressive effect and are regarded as promising cellular therapeutic agents for immunological diseases resistant to treatment. MSCs have been established from various tissues (umbilical cord blood, placenta, adipose tissue, etc.), among which adipose tissue contains a particularly large amount of cells.

Clinical research and treatment using adipose-derived mesenchymal stem cells (MSC-ATs) [3] is already underway in many medical institutions around the world [4]. The clinical practical application of islet cell transplantation therapy was reported in 2000 in the Edmonton protocol [5] and many subsequent papers [6-10]. The technology of islet transplantation is thought to be useful for the processing of therapeutic cells using MSC-ATs. We recently reported that the University of Wisconsin (UW) [11] organ preservation solution has a better cell survival/proliferation ability than Hank’s balanced salt solution (HBSS) [12]. There is a possibility that the adipose tissue collected through the patient’s skin may be infected with skin bacteria. One method of sterilizing tissues collected from a living body involves immersing and storing such tissue for 16 h using HBSS [13], which also contains antibiotics. After such storage, MSC-ATs can be isolated from adipose tissue. In addition, adipose tissue collected from a patient can be transported to a remote location.

It was recently reported that the stress of long-term culture of cells in vitro also occurs in stem cells, such as induced pluripotent stem (iPS) cells, causing DNA damage and cellular carcinogenesis [14]. Some researchers recommend reducing the number of passages of MSC-ATs to maintain the quality of primary cultured cells. However, MSC-ATs of primary cultured cells are reportedly contaminated with various types of cells, such as blood cells, through the process of cell isolation. This is because the stromal vascular fraction (SVF) [15] obtained when collecting MSC-ATs using centrifugation contains many kinds of cells (e.g., adipocytes, fibroblasts, smooth muscle cells, endothelial cells, blood cells, endothelial progenitor cells, preadipocytes, vascular progenitors, hematopoietic progenitors, and hematopoietic stem cells) [16, 17]. For MSC-ATs isolated from adipocytes collected from patients, the number of cells can be increased by increasing the number of passages. Because this processing can be done outside the body, the patient can thus obtain many of her/his own cells after undergoing only one procedure of fat collection surgery. However, it is also important to maintain the quality of the cells. Therefore, researchers and clinicians have fervently discussed how many passaging operations of clinical MSC-ATs should be performed.

With liquid chromatography (or high-performance liquid chromatography (HPLC)) with tandem mass spectrometry (LC-MS/MS), the components to be analyzed are separated by a liquid chromatograph (LC) and ionized via a dedicated interface (ion source) and the generated ions are then separated by MS. LC-MS/MS is an analytical technique that dissociates and fragments mass ions and detects them with MS [18]. Recently, an online LC-MS/MS system for quantitative proteomics based on data-dependent protein IDs and shotgun-based quantitative proteomics methods was developed [19-23] by connecting the measuring equipment for a protein analysis to a computer and linking to an online protein database. In this way, a comprehensive protein expression analysis can be performed by checking the peptide sequence data of the protein contained in the sample.

A comprehensive expression analysis of the protein expressed by the cell is important for accurately understanding the mechanism underlying the effect of cell therapy accompanying the administration of the culture supernatant of cells and the cells themselves. The present study was performed to identify the functional protein components in mouse MSC-ATs of primary cultured cells (P0) and mMSC-ATs passaged three times (P3) using LC-MS/MS. The proteins specifically contained in primary cultured cells were identified as those expressed only in the SVF derived from AT. By examining the proteins expressed in both P0 and P3 cells, we can identify the proteins expressed by MSC-ATs. Determining the protein component of MSC-ATs that exerts a therapeutic effect is expected to be useful for cell therapy in the future.

2. Materials and Methods

2.1. Reagents

Fetal bovine serum (FBS) was obtained from Biowest (Nuaille, France). DMEM (high glucose) with L-glutamine, phenol red, and sodium pyruvate was obtained from FUJIFILM Wako Pure Chemical Corporation (Osaka, Japan). Plastic dishes were obtained from TPP (Trasadingen, Switzerland). All other materials used were of the highest commercial grade.

2.2. Animal Care

All experimental protocols were in accordance with the guidelines for the care and use of laboratory animals set by Research Laboratory Center, Faculty of Medicine, and the Institute for Animal Experiments, Faculty of Medicine, University of the Ryukyus (Okinawa, Japan). The experimental protocol was approved by the Committee on Animal Experiments of University of the Ryukyus (permit number: A2017101). C57BL/6 male mice (8 weeks of age; Japan SLC, Shizuoka, Japan) were maintained under controlled temperature (23 ± 2°C) and light conditions (lights on from 08:30 to 20:30). Animals were fed standard rodent chow pellets with ad libitum access to water. All efforts were made to minimize the suffering of the animals.

2.3. Isolation of MSC-ATs from Mouse via the Inguinal Pad Fat

AT was obtained from the inguinal pad fat of three 8-week-old mice. The method of isolating MSC-ATs from AT was in accordance with the AT-derived stem cell product standard document (RMRC-A 01: 2015) of Ryukyus Regenerative Medicine Research Center. In brief, these ATs were stored in cold HBSS and washed vigorously using HBSS three times before starting digestion. Next, the tissues were cut into small fragments with a scalpel for enzymatic digestion (2 mg collagenase type IV/ml; HBSS) in 50 ml tubes (rotation speed: 20 × 37°C × 60 min) using the shaker (BioShaker BR-42FM; TAITEC, Saitama, Japan). These tubes were then centrifuged (800g) for 5 minutes. The SVF [24] containing various kinds of cells, including MSC-ATs, was confirmed at the bottom of the tube after centrifugation. The MSC-ATS were collected as a cell pellet and then washed with fresh DMEM containing 10% FBS to remove the enzyme after the digestion. The digested tissue was then incubated in a T25 flask.

All of the mouse studies were approved by the Institutional Animal Care and Use Committee of University of the Ryukyus.

2.4. Preparation of mMSC-ATs

Mouse MSC-ATs were cultured (37°C, 5% CO2) in an uncoated T25 flask (TPP 90026). The passage of cells was performed every 3 to 4 days after reaching 80% confluence following sowing. The cells were then washed with PBS (calcium, magnesium-free), and mouse MSC-ATs were dissociated using a dissociation solution (Trypsin/EDTA (Lonza CC-3232)). Subculturing was carried out by plating on an uncoated T25 flask. DMEM containing 10% FBS was used for the culture medium.

2.5. Flow Cytometry

Cell flow cytometry was performed as described previously [25], using specific antibodies for CD34, CD 44, CD45, and CD90.2.

2.6. Cell Differentiation

Adipogenic and osteogenic differentiations were performed as described previously [25].

2.7. Protein Identification by a Nano-LC-MS/MS Analysis

We used an EzRIPA Lysis kit (ATTO Corporation, Tokyo, Japan) for cell lysis according to the manufacturer’s instructions. A protein solution of 4493 μg/ml (P0) and 3105 μg/ml (P3) was obtained from mADSCs, and 6.0 μg protein was used for sample preparation. Finally, 0.4 μg of protein was used for nano-LC-MS/MS. The comprehensive expression analysis of proteins using LC-MS/MS and data analyses were performed according to the method reported previously [25].

3. Results and Discussion

The application of cell therapy in regenerative medicine is expected to be useful for the treatment of many kinds of diseases. For example, MSC-ATs, which can be collected from AT, have been applied to the treatment of a wide range of diseases in light of the low invasiveness compared with surgery. It is generally recognized that MSC-ATs are stable in quality from P0 cells to P5 cells [26]. As such, many manuals of commercially available MSC-ATs state that the quality is guaranteed for five passages. It was reported that multiple passaging processes reduce both the cell proliferative activity and the cell surface marker expression [27] and induce chromosome abnormalities [15]. In addition, increasing the number of passages also increases the risk of microbial infection of cells. Therefore, the general perception among clinical researchers dealing with therapeutic cells is that MSC-ATs are only useful as therapeutic cells within the first five passages [28].

However, it is easy to imagine that preparing cells collected from a living organism without subculturing may enable the production of therapeutic cells with new and special functions. Therefore, clinicians may try using MSC-ATs isolated from AT without any culturing or P0 MSC-ATs. Close attention must be paid in such cases, as immune rejection can be caused when using therapeutic cells not only for autologous transplantation but also other transplantations as well.

3.1. The Characteristics and Cell Quality of mMSC-ATs (P0)

mMSC-ATs were cultured to 80% confluence using DMEM containing 10% FBS after isolation from AT. The whole medium was exchanged every two days. Microscopy was performed to confirm the absence of abnormalities with regard to the mMSC-AT (P0) size and shape and the culture state (Figure 1(a), left panel). Flow cytometry was performed using markers of mMSC-ATs (CD44, CD90.2), hematopoietic stem cells (CD34), and leukocytes (CD45). CD44 and CD90.2 were expressed in mMSC-ATs, while CD34 and CD45 were not detected (Figure 1(a), right panels). We induced differentiation into adipocytes (Figure 1(b), left panel) and osteoblasts (Figure 1(b), right panel) using mMSC-ATs. Mature adipocytes were stained with Oil Red O, and mature osteoblasts were stained with Alizarin Red S.

Details are in the caption following the image
The phenotype and differentiation potential of mMSC-ATs in culture. The morphological appearance of mMSC-ATs (P0) ((a) left panel; scale bar = 800 μm). The results of flow cytometry of the cell surface markers of mMSC-ATs (P0) ((a) right panels). Representative images of adipocyte ((b) left panel; scale bar = 100 μm) and osteocyte differentiation ((b) right panel; scale bar = 200 μm) of mouse MSC-ATs (P0) cultured in differentiation medium. The morphological appearance of mMSC-ATs (P3) ((c) left panel; scale bar = 800 μm). The results of flow cytometry of the cell surface markers of mMSC-ATs (P3) ((c) right panels). Representative images of adipocyte ((d) left panel; scale bar = 100 μm) and osteocyte differentiation ((d) right panel; scale bar = 200 μm) of mouse MSC-ATs (P3) cultured in differentiation medium.
Details are in the caption following the image
The phenotype and differentiation potential of mMSC-ATs in culture. The morphological appearance of mMSC-ATs (P0) ((a) left panel; scale bar = 800 μm). The results of flow cytometry of the cell surface markers of mMSC-ATs (P0) ((a) right panels). Representative images of adipocyte ((b) left panel; scale bar = 100 μm) and osteocyte differentiation ((b) right panel; scale bar = 200 μm) of mouse MSC-ATs (P0) cultured in differentiation medium. The morphological appearance of mMSC-ATs (P3) ((c) left panel; scale bar = 800 μm). The results of flow cytometry of the cell surface markers of mMSC-ATs (P3) ((c) right panels). Representative images of adipocyte ((d) left panel; scale bar = 100 μm) and osteocyte differentiation ((d) right panel; scale bar = 200 μm) of mouse MSC-ATs (P3) cultured in differentiation medium.
Details are in the caption following the image
The phenotype and differentiation potential of mMSC-ATs in culture. The morphological appearance of mMSC-ATs (P0) ((a) left panel; scale bar = 800 μm). The results of flow cytometry of the cell surface markers of mMSC-ATs (P0) ((a) right panels). Representative images of adipocyte ((b) left panel; scale bar = 100 μm) and osteocyte differentiation ((b) right panel; scale bar = 200 μm) of mouse MSC-ATs (P0) cultured in differentiation medium. The morphological appearance of mMSC-ATs (P3) ((c) left panel; scale bar = 800 μm). The results of flow cytometry of the cell surface markers of mMSC-ATs (P3) ((c) right panels). Representative images of adipocyte ((d) left panel; scale bar = 100 μm) and osteocyte differentiation ((d) right panel; scale bar = 200 μm) of mouse MSC-ATs (P3) cultured in differentiation medium.
Details are in the caption following the image
The phenotype and differentiation potential of mMSC-ATs in culture. The morphological appearance of mMSC-ATs (P0) ((a) left panel; scale bar = 800 μm). The results of flow cytometry of the cell surface markers of mMSC-ATs (P0) ((a) right panels). Representative images of adipocyte ((b) left panel; scale bar = 100 μm) and osteocyte differentiation ((b) right panel; scale bar = 200 μm) of mouse MSC-ATs (P0) cultured in differentiation medium. The morphological appearance of mMSC-ATs (P3) ((c) left panel; scale bar = 800 μm). The results of flow cytometry of the cell surface markers of mMSC-ATs (P3) ((c) right panels). Representative images of adipocyte ((d) left panel; scale bar = 100 μm) and osteocyte differentiation ((d) right panel; scale bar = 200 μm) of mouse MSC-ATs (P3) cultured in differentiation medium.

3.2. The Characteristics and Cell Quality of mMSC-ATs (P3)

mMSC-ATs were cultured to 80% confluence using DMEM containing 10% FBS after isolation from adipose tissue. The whole medium was exchanged every two days. The passage of cells was performed every 3 to 4 days after reaching 80% confluence. Microscopy was performed to confirm the absence of abnormalities with regard to the mMSC-AT (P3) size and shape and the culture state (Figure 1(c), left panel). Flow cytometry was performed using markers of mMSC-ATs (CD44, CD90.2), hematopoietic stem cells (CD34) and leukocytes (CD45). CD44 and CD90.2 were expressed in mMSC-ATs while CD34 and CD45 were not detected (Figure 1(c), right panels). We induced differentiation into adipocytes (Figure 1(d), left panel) and osteoblasts (Figure 1(d), right panel) using mMSC-ATs. Mature adipocytes were stained with Oil Red O, and mature osteoblasts were stained with Alizarin Red S.

A proteome analysis using LC-MS/MS provided evidence supporting the safe application of cell therapy with MSCs and supplied information on the potential application of MSCs in various treatments. A protein analysis indicates the protein components present in the cell component. In this study, mMSC-ATs were used, but when human MSC-ATs are used, this analysis will show the protein components that should be administered to patients.

3.3. A Comprehensive Protein Expression Analysis of mMSC-ATs (P0 and P3)

We performed mMSC-AT isolation according to a protocol similar to that used in clinical studies at the University of the Ryukyus, and isolated mMSC-ATs were subjected to LC-MS/MS after 0 or 3 passages. The presence of a large amount of albumin in the medium reduces the accuracy in protein analyses. Therefore, the protein extracts obtained from the cells after washing with phosphate-buffered saline (PBS) were used in this study.

There were 1785 types of proteins identified from the mMSC-AT (P0) samples (Table 1) and 1825 types of proteins identified from the mMSC-AT (P3) samples (Table 2). Among the 1785 types of proteins in mouse P0 cells, there were 336 types of proteins unique to the primary cultured cells (group P0). A total of 1449 types of proteins in mouse P0 cells were also identified in mouse P3 cells (group P0&P3). Among the 1825 types of proteins in mouse P3 cells, there were 376 types of proteins unique to the cells passaged 3 times (group P3) (Figure 2). Therefore, the 336 types of proteins whose expression was eliminated by passage were deemed likely to have been derived from the different types of cells contained in the SVF.

Table 1. Identification of endogenous proteins contained in mMSC-AT_P0 (primary cultured cells).
UniProt/Swiss-Prot ID Description Protein scorea Protein mass (kDa) pIb Num. of matchesc Num. of significant matchesd Num. of sequencese Num. of significant sequencesf Num. of unique sequencesg Sequence coverageh emPAIi
FLNA_MOUSE Filamin-A 2702 281046 5.68 220 138 87 56 81 0.54 1.34
FLNB_MOUSE Filamin-B 1877 277651 5.46 164 94 81 51 73 0.52 1.23
FLNC_MOUSE Filamin-C 1471 290937 5.63 115 68 57 33 11 0.39 0.68
MYH9_MOUSE Myosin-9 2689 226232 5.54 232 114 116 57 100 0.64 2.27
TLN1_MOUSE Talin-1 2390 269653 5.84 147 98 72 53 52 0.49 1.39
IQGA1_MOUSE Ras GTPase-activating-like protein IQGAP1 1740 188624 6.07 97 56 53 33 53 0.47 1.13
CLH1_MOUSE Clathrin heavy chain 1 1668 191435 5.48 114 80 64 49 64 0.6 2.26
CH60_MOUSE 60 kDa heat shock protein, mitochondrial 1558 60917 5.91 75 58 29 22 29 0.66 5.35
DYHC1_MOUSE Cytoplasmic dynein 1 heavy chain 1 1460 531710 6.03 121 67 85 48 85 0.3 0.47
ACTN1_MOUSE Alpha-actinin-1 1455 103004 5.23 99 55 44 29 26 0.63 2.67
ACTN4_MOUSE Alpha-actinin-4 914 104911 5.25 76 36 39 23 21 0.56 1.5
HSP7C_MOUSE Heat shock cognate 71 kDa protein 1427 70827 5.37 147 72 34 26 27 0.72 4.53
GRP78_MOUSE 78 kDa glucose-regulated protein 1101 72377 5.07 114 54 35 23 32 0.64 2.77
GRP75_MOUSE Stress-70 protein, mitochondrial 851 73416 5.81 65 36 22 17 21 0.46 1.79
HS71A_MOUSE Heat shock 70 kDa protein 1A 246 70036 5.53 34 13 12 7 8 0.34 0.52
NSF_MOUSE Vesicle-fusing ATPase 98 82561 6.52 8 4 7 4 7 0.15 0.22
TBB6_MOUSE Tubulin beta-6 chain 517 50058 4.8 59 35 24 17 10 0.79 3.86
VIME_MOUSE Vimentin 1321 53655 5.06 170 69 45 30 45 0.76 9.3
ENPL_MOUSE Endoplasmin 1314 92418 4.74 108 60 44 32 20 0.58 4.09
HS90A_MOUSE Heat shock protein HSP 90-alpha 1047 84735 4.93 93 47 38 22 25 0.56 2.27
ENOA_MOUSE Alpha-enolase 1304 47111 6.37 95 58 23 17 23 0.74 6
FAS_MOUSE Fatty acid synthase 1264 272257 6.13 89 59 61 44 61 0.45 1.03
G3P_MOUSE Glyceraldehyde-3-phosphate dehydrogenase 1238 35787 8.44 94 50 19 13 15 0.76 9.22
KPYM_MOUSE Pyruvate kinase PKM 1232 57808 7.18 98 58 37 30 12 0.74 13.41
ACTBL_MOUSE Beta-actin-like protein 2 361 41977 5.3 52 22 13 5 4 0.51 1.44
TSP1_MOUSE Thrombospondin-1 1160 129564 4.72 117 62 35 17 34 0.36 0.91
ATPA_MOUSE ATP synthase subunit alpha, mitochondrial 1118 59716 9.22 64 44 24 18 16 0.58 3.34
SPB6_MOUSE Serpin B6 1096 42571 5.53 49 36 21 14 21 0.71 4.79
ILEUA_MOUSE Leukocyte elastase inhibitor A 99 42548 5.85 4 4 3 3 3 0.11 0.34
GDN_MOUSE Glia-derived nexin 84 44179 9.85 6 4 5 4 5 0.16 0.46
FINC_MOUSE Fibronectin 1089 272368 5.39 97 52 57 34 57 0.4 0.69
EF2_MOUSE Elongation factor 2 1085 95253 6.41 91 53 47 28 46 0.66 2.42
UBA1_MOUSE Ubiquitin-like modifier-activating enzyme 1 1077 117734 5.43 55 39 26 19 26 0.45 1.11
RINI_MOUSE Ribonuclease inhibitor 991 49784 4.69 48 34 23 17 19 0.81 3.14
PDIA1_MOUSE Protein disulfide-isomerase 965 57023 4.77 91 48 34 21 34 0.62 3.99
ATPB_MOUSE ATP synthase subunit beta, mitochondrial 853 56265 5.19 65 39 28 22 26 0.81 4.5
TCPA_MOUSE T-complex protein 1 subunit alpha 833 60411 5.82 44 25 23 12 23 0.64 2.02
1433Z_MOUSE 14-3-3 protein zeta/delta 831 27754 4.73 46 29 15 11 12 0.6 4.16
1433B_MOUSE 14-3-3 protein beta/alpha 539 28069 4.77 28 19 13 10 3 0.63 3.37
CO1A1_MOUSE Collagen alpha-1(I) chain 825 137948 5.65 141 65 42 24 25 0.53 1.27
HSP74_MOUSE Heat shock 70 kDa protein 4 817 94073 5.15 56 29 26 18 25 0.46 1.22
HS105_MOUSE Heat shock protein 105 kDa 118 96346 5.39 14 6 12 5 11 0.25 0.24
LRP1_MOUSE Prolow-density lipoprotein receptor-related protein 1 815 504411 5.14 75 39 54 26 54 0.22 0.24
WDR1_MOUSE WD repeat-containing protein 1 796 66365 6.11 35 23 18 12 18 0.57 1.13
LDHA_MOUSE L-Lactate dehydrogenase A chain 752 36475 7.62 81 28 19 11 19 0.79 3.92
ANXA1_MOUSE Annexin A1 750 38710 6.97 50 27 21 11 21 0.61 2.26
MOES_MOUSE Moesin 737 67725 6.22 73 32 34 15 23 0.61 2.03
TKT_MOUSE Transketolase 732 67588 7.23 53 32 26 16 26 0.69 2.04
SERPH_MOUSE Serpin H1 731 46504 8.88 56 35 23 16 23 0.68 4.01
SC31A_MOUSE Protein transport protein Sec31A 707 133486 6.3 30 23 15 13 15 0.27 0.55
ALDOA_MOUSE Fructose-bisphosphate aldolase A 674 39331 8.31 56 33 23 15 23 0.83 5.04
VDAC1_MOUSE Voltage-dependent anion-selective channel protein 1 667 32331 8.55 31 23 11 9 11 0.67 2.61
VDAC2_MOUSE Voltage-dependent anion-selective channel protein 2 454 31713 7.44 25 19 10 8 10 0.54 1.84
RPN2_MOUSE Dolichyl-diphosphooligosaccharide–protein glycosyltransferase subunit 2 666 69020 5.54 34 24 19 16 19 0.52 1.63
ASSY_MOUSE Argininosuccinate synthase 660 46555 8.36 54 25 24 12 22 0.75 2.5
SYAC_MOUSE Alanine–tRNA ligase, cytoplasmic 658 106841 5.45 46 25 29 18 29 0.55 1.02
UGGG1_MOUSE UDP-glucose:glycoprotein glucosyltransferase 1 656 176323 5.4 34 20 24 15 24 0.3 0.43
ANXA5_MOUSE Annexin A5 647 35730 4.83 65 34 19 12 18 0.71 4.71
ANXA3_MOUSE Annexin A3 313 36362 5.5 29 16 17 12 16 0.64 2.93
ANXA6_MOUSE Annexin A6 196 75837 5.34 17 11 12 8 12 0.27 0.55
ANX11_MOUSE Annexin A11 53 54045 7.53 4 3 3 2 3 0.11 0.17
CO1A2_MOUSE Collagen alpha-2(I) chain 645 129478 9.27 61 38 29 17 29 0.44 0.85
6PGD_MOUSE 6-Phosphogluconate dehydrogenase, decarboxylating 642 53213 6.81 38 21 19 14 19 0.63 2
SPTN1_MOUSE Spectrin alpha chain, nonerythrocytic 1 639 284422 5.2 61 37 45 25 45 0.32 0.45
AT1A1_MOUSE Sodium/potassium-transporting ATPase subunit alpha-1 619 112910 5.3 47 26 25 15 25 0.34 0.74
GDIB_MOUSE Rab GDP dissociation inhibitor beta 615 50505 5.93 40 22 18 10 13 0.58 1.48
GDIA_MOUSE Rab GDP dissociation inhibitor alpha 274 50489 4.96 25 13 13 9 8 0.49 1.28
EF1G_MOUSE Elongation factor 1-gamma 613 50029 6.31 43 29 21 14 21 0.67 2.48
TCPQ_MOUSE T-complex protein 1 subunit theta 611 59518 5.44 35 19 20 12 20 0.53 1.32
MDHM_MOUSE Malate dehydrogenase, mitochondrial 603 35589 8.93 39 27 16 11 16 0.58 3.55
PDIA4_MOUSE Protein disulfide-isomerase A4 602 71938 5.16 50 29 21 13 21 0.45 1.39
CAP1_MOUSE Adenylyl cyclase-associated protein 1 594 51532 7.16 58 28 24 14 24 0.73 2.1
IMB1_MOUSE Importin subunit beta-1 584 97122 4.68 33 24 24 17 24 0.41 1.08
CAPG_MOUSE Macrophage-capping protein 263 39216 6.73 16 8 6 5 1 0.3 0.7
ESTD_MOUSE S-Formylglutathione hydrolase 576 31299 6.7 50 28 17 12 17 0.87 5.39
CAN2_MOUSE Calpain-2 catalytic subunit 566 79822 4.86 37 28 23 20 20 0.58 2
VATB2_MOUSE V-type proton ATPase subunit B, brain isoform 562 56515 5.57 40 27 20 14 20 0.69 2.03
VPS35_MOUSE Vacuolar protein sorting-associated protein 35 561 91655 5.28 32 21 16 10 16 0.3 0.58
LYAG_MOUSE Lysosomal alpha-glucosidase 561 106180 5.53 34 26 20 16 20 0.37 0.88
ACLY_MOUSE ATP-citrate synthase 559 119651 7.13 34 23 27 18 27 0.39 0.94
FPPS_MOUSE Farnesyl pyrophosphate synthase 554 40556 5.49 31 18 17 10 17 0.61 1.79
COPG1_MOUSE Coatomer subunit gamma-1 553 97450 5.23 35 22 24 18 20 0.46 1.16
IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytoplasmic 552 46644 6.73 35 25 17 10 16 0.57 1.92
VIGLN_MOUSE Vigilin 550 141655 6.43 40 24 27 15 27 0.34 0.56
P4HA1_MOUSE Prolyl 4-hydroxylase subunit alpha-1 546 60872 5.62 33 18 17 12 17 0.5 1.44
CATB_MOUSE Cathepsin B 542 37256 5.57 39 24 13 11 13 0.6 3.26
VINC_MOUSE Vinculin 520 116644 5.77 53 24 33 19 33 0.41 0.98
CNDP2_MOUSE Cytosolic nonspecific dipeptidase 516 52734 5.43 41 23 20 15 20 0.67 2.27
SEPT2_MOUSE Septin-2 515 41499 6.1 22 16 14 9 14 0.56 1.46
DPYL2_MOUSE Dihydropyrimidinase-related protein 2 509 62239 5.95 43 25 25 15 22 0.73 1.73
DPYL3_MOUSE Dihydropyrimidinase-related protein 3 203 61897 6.04 16 9 8 4 5 0.21 0.31
TAGL2_MOUSE Transgelin-2 509 22381 8.39 42 28 14 11 14 0.8 8.1
TCPH_MOUSE T-complex protein 1 subunit eta 501 59614 7.95 34 22 18 15 18 0.53 2.06
FRIL1_MOUSE Ferritin light chain 1 500 20790 5.66 18 15 6 4 6 0.49 1.7
NCPR_MOUSE NADPH–cytochrome P450 reductase 499 76995 5.34 19 15 12 8 12 0.33 0.54
TCPZ_MOUSE T-complex protein 1 subunit zeta 491 57968 6.63 30 18 19 12 19 0.55 1.37
VATA_MOUSE V-type proton ATPase catalytic subunit A 481 68283 5.42 43 23 27 14 27 0.6 1.35
XDH_MOUSE Xanthine dehydrogenase/oxidase 475 146468 7.62 28 23 16 14 16 0.24 0.54
PDC6I_MOUSE Programmed cell death 6-interacting protein 475 95964 6.15 25 17 17 12 17 0.35 0.76
CAND1_MOUSE Cullin-associated NEDD8-dissociated protein 1 473 136245 5.52 26 19 20 14 20 0.33 0.64
COF1_MOUSE Cofilin-1 473 18548 8.22 30 18 11 9 9 0.61 6.37
COF2_MOUSE Cofilin-2 182 18698 7.66 20 10 6 4 4 0.49 1.42
LG3BP_MOUSE Galectin-3-binding protein 471 64450 5 17 12 10 6 9 0.3 0.47
VAT1_MOUSE Synaptic vesicle membrane protein VAT-1 homolog 471 43069 5.95 44 25 21 14 21 0.65 3.69
TCPD_MOUSE T-complex protein 1 subunit delta 467 58030 8.24 35 17 20 9 20 0.59 0.91
AMPN_MOUSE Aminopeptidase N 465 109582 5.62 26 21 17 16 17 0.3 0.84
PPIA_MOUSE Peptidyl-prolyl cis-trans isomerase A 465 17960 7.74 33 21 11 8 11 0.7 11.36
MDHC_MOUSE Malate dehydrogenase, cytoplasmic 464 36488 6.16 21 14 10 6 10 0.52 1.22
G6PI_MOUSE Glucose-6-phosphate isomerase 462 62727 8.14 29 18 15 10 8 0.4 1.08
PDIA3_MOUSE Protein disulfide-isomerase A3 449 56643 5.88 115 29 32 16 32 0.64 2.77
THIO_MOUSE Thioredoxin 445 11668 4.8 24 16 7 6 7 0.78 7.1
RLA0_MOUSE 60S acidic ribosomal protein P0 441 34195 5.91 30 21 14 10 14 0.56 2.8
ESYT1_MOUSE Extended synaptotagmin-1 437 121478 5.63 20 17 13 11 13 0.22 0.46
2AAA_MOUSE Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 437 65281 5 20 14 17 12 17 0.46 1.15
PTBP1_MOUSE Polypyrimidine tract-binding protein 1 437 56443 8.47 22 11 8 5 8 0.36 0.68
AT2A2_MOUSE Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 436 114784 5.23 33 20 20 12 20 0.32 0.55
SPTB2_MOUSE Spectrin beta chain, nonerythrocytic 1 429 274052 5.4 52 21 39 20 39 0.25 0.38
SCOT1_MOUSE Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial 428 55953 8.73 29 20 14 12 14 0.5 1.63
CALR_MOUSE Calreticulin 419 47965 4.33 43 26 19 11 19 0.6 1.84
CKAP4_MOUSE Cytoskeleton-associated protein 4 418 63654 5.46 48 27 25 13 25 0.54 1.86
MYOF_MOUSE Myoferlin 417 233177 5.83 44 17 30 12 30 0.24 0.24
GSTP1_MOUSE Glutathione S-transferase P 1 417 23594 7.68 21 14 9 7 9 0.58 3.82
PLEC_MOUSE Plectin 416 533861 5.74 66 21 52 16 52 0.18 0.13
TCPB_MOUSE T-complex protein 1 subunit beta 414 57441 5.97 27 15 20 13 20 0.56 1.57
KAD1_MOUSE Adenylate kinase isoenzyme 1 410 21526 5.67 15 13 9 8 6 0.64 3.63
PRDX6_MOUSE Peroxiredoxin-6 405 24855 5.71 36 18 16 11 16 0.75 5.23
RL9_MOUSE 60S ribosomal protein L9 401 21868 9.96 12 10 5 4 5 0.48 1.13
UGDH_MOUSE UDP-glucose 6-dehydrogenase 398 54797 7.49 33 18 22 14 22 0.66 1.9
CATD_MOUSE Cathepsin D 389 44925 6.71 35 21 15 9 15 0.55 2.33
NIBL1_MOUSE Niban-like protein 1 388 84765 5.65 23 15 18 13 18 0.36 0.9
TXND5_MOUSE Thioredoxin domain-containing protein 5 386 46386 5.51 17 14 8 5 8 0.32 0.57
TSP2_MOUSE Thrombospondin-2 385 129798 4.61 44 19 22 10 21 0.28 0.38
MAOX_MOUSE NADP-dependent malic enzyme 384 63913 7.16 15 11 14 10 14 0.49 0.92
ARF4_MOUSE ADP-ribosylation factor 4 382 20384 6.59 23 15 11 8 5 0.83 6.52
COPB2_MOUSE Coatomer subunit beta  381 102384 5.17 33 20 24 15 24 0.43 0.85
PRDX1_MOUSE Peroxiredoxin-1 379 22162 8.26 87 35 20 14 19 0.8 15.25
PRDX2_MOUSE Peroxiredoxin-2 316 21765 5.2 16 11 8 7 8 0.45 2.77
PRDX4_MOUSE Peroxiredoxin-4 152 31033 6.67 18 7 11 5 10 0.52 0.95
PLSL_MOUSE Plastin-2 378 70105 5.2 35 21 22 13 20 0.48 1.17
GPNMB_MOUSE Transmembrane glycoprotein NMB 378 63635 7.55 27 16 10 5 10 0.22 0.48
GELS_MOUSE Gelsolin 371 85888 5.83 32 21 17 13 17 0.45 0.98
THIC_MOUSE Acetyl-CoA acetyltransferase, cytosolic 371 41271 7.16 20 12 12 8 12 0.59 1.24
ECHA_MOUSE Trifunctional enzyme subunit alpha, mitochondrial 371 82617 9.24 24 16 16 10 16 0.44 0.66
MYO1C_MOUSE Unconventional myosin-Ic 370 121868 9.41 34 17 29 14 29 0.4 0.62
PDIA6_MOUSE Protein disulfide-isomerase A6 369 48070 5 29 22 14 12 14 0.48 1.83
EIF3L_MOUSE Eukaryotic translation initiation factor 3 subunit L 368 66570 6.01 16 11 7 5 7 0.21 0.37
MVP_MOUSE Major vault protein 365 95865 5.43 30 16 17 10 17 0.35 0.55
HYOU1_MOUSE Hypoxia-upregulated protein 1 362 111112 5.12 18 10 15 8 15 0.27 0.35
FABP5_MOUSE Fatty acid-binding protein, epidermal 361 15127 6.14 35 19 8 6 8 0.66 7.75
IPO5_MOUSE Importin-5 358 123511 4.82 42 28 25 19 25 0.44 1.11
TCPE_MOUSE T-complex protein 1 subunit epsilon 356 59586 5.72 27 17 17 10 17 0.45 1.16
OST48_MOUSE Dolichyl-diphosphooligosaccharide–protein glycosyltransferase 48 kDa subunit 355 48997 5.52 21 13 11 5 11 0.38 0.81
SYRC_MOUSE Arginine–tRNA ligase, cytoplasmic 354 75625 7.48 19 11 14 7 14 0.31 0.56
NB5R3_MOUSE NADH-cytochrome b5 reductase 3 354 34106 8.55 26 18 12 10 12 0.68 2.82
NDKB_MOUSE Nucleoside diphosphate kinase B 353 17352 6.97 30 14 10 4 6 0.74 3.15
NDKA_MOUSE Nucleoside diphosphate kinase A 171 17197 6.84 22 11 7 5 3 0.59 4.32
CO5A1_MOUSE Collagen alpha-1(V) chain 351 183564 4.86 13 11 8 6 8 0.1 0.15
RLA2_MOUSE 60S acidic ribosomal protein P2 348 11644 4.42 13 9 5 5 5 0.7 4.72
AK1A1_MOUSE Alcohol dehydrogenase [NADP(+)] 344 36564 6.9 23 16 16 11 16 0.64 2.92
ALDR_MOUSE Aldose reductase 114 35709 6.71 14 6 7 4 7 0.26 0.59
PCBP2_MOUSE Poly(rC)-binding protein 2 343 38197 6.33 32 17 12 8 2 0.55 1.66
NEDD4_MOUSE E3 ubiquitin-protein ligase NEDD4 343 102642 5.12 29 17 18 11 18 0.33 0.57
UAP1L_MOUSE UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 342 56578 5.27 28 15 19 11 17 0.55 1.25
UAP1_MOUSE UDP-N-acetylhexosamine pyrophosphorylase 87 58572 6.04 4 3 2 2 1 0.06 0.15
CLIC1_MOUSE Chloride intracellular channel protein 1 342 26996 5.09 24 13 14 8 13 0.72 2.41
GSLG1_MOUSE Golgi apparatus protein 1 342 133646 6.45 20 11 16 7 11 0.2 0.28
DNJC3_MOUSE DnaJ homolog subfamily C member 3 341 57428 5.61 9 5 6 3 6 0.29 0.24
FSCN1_MOUSE Fascin 340 54474 6.44 24 10 15 8 15 0.51 0.84
SODM_MOUSE Superoxide dismutase [Mn], mitochondrial 340 24588 8.8 12 9 5 4 5 0.46 0.96
PROF1_MOUSE Profilin-1 339 14948 8.46 65 22 11 7 11 0.78 10.68
MBB1A_MOUSE Myb-binding protein 1A 339 151942 9.08 21 15 15 10 15 0.18 0.32
CISY_MOUSE Citrate synthase, mitochondrial 338 51703 8.72 23 14 16 11 16 0.56 1.63
SAP_MOUSE Prosaposin 338 61381 5.07 45 16 19 10 19 0.49 1.11
ADT1_MOUSE ADP/ATP translocase 1 278 32883 9.73 25 9 16 7 9 0.61 1.42
CPNS1_MOUSE Calpain small subunit 1 337 28445 5.41 14 9 7 5 7 0.41 1.07
UGPA_MOUSE UTP–glucose-1-phosphate uridylyltransferase 335 56944 7.18 14 9 9 6 9 0.3 0.55
NACAM_MOUSE Nascent polypeptide-associated complex subunit alpha, muscle-specific form 330 220364 9.39 20 12 8 3 8 0.06 0.06
DLDH_MOUSE Dihydrolipoyl dehydrogenase, mitochondrial 329 54238 7.99 16 12 10 7 10 0.39 0.71
HNRPF_MOUSE Heterogeneous nuclear ribonucleoprotein F 327 45701 5.31 17 10 10 6 8 0.42 0.73
OAT_MOUSE Ornithine aminotransferase, mitochondrial 326 48324 6.19 25 14 9 6 9 0.4 0.68
DHB12_MOUSE Very-long-chain 3-oxoacyl-CoA reductase 324 34719 9.55 18 13 12 9 12 0.56 1.93
DHE3_MOUSE Glutamate dehydrogenase 1, mitochondrial 323 61298 8.05 36 16 16 9 16 0.44 0.85
CATS_MOUSE Cathepsin S 323 38449 6.51 18 10 12 7 12 0.53 1.13
ITB5_MOUSE Integrin beta-5 322 87851 5.81 18 14 10 7 10 0.25 0.4
CATL1_MOUSE Cathepsin L1 321 37523 6.37 13 10 8 6 8 0.5 1.43
PSMD1_MOUSE 26S proteasome non-ATPase regulatory subunit 1 321 105663 5.25 20 12 15 10 15 0.29 0.49
RPN1_MOUSE Dolichyl-diphosphooligosaccharide–protein glycosyltransferase subunit 1 320 68486 6.02 32 19 19 11 19 0.45 0.96
LYOX_MOUSE Protein-lysine 6-oxidase 319 46671 8.73 20 13 8 5 8 0.37 0.56
AOFA_MOUSE Amine oxidase [flavin-containing] A 319 59564 7.9 19 14 12 7 12 0.39 0.63
PSD12_MOUSE 26S proteasome non-ATPase regulatory subunit 12 315 52861 6.66 22 12 15 7 15 0.43 0.74
COCA1_MOUSE Collagen alpha-1(XII) chain 315 340004 5.47 39 19 24 14 24 0.15 0.19
ALDH2_MOUSE Aldehyde dehydrogenase, mitochondrial 315 56502 7.53 39 20 19 14 19 0.62 2.03
PP1A_MOUSE Serine/threonine-protein phosphatase PP1-alpha catalytic subunit 314 37516 5.94 15 12 10 7 10 0.37 1.17
TPIS_MOUSE Triosephosphate isomerase 312 32171 5.56 36 14 14 9 14 0.64 2.63
GSTM1_MOUSE Glutathione S-transferase Mu 1 311 25953 7.71 32 13 12 6 9 0.61 2.05
GSTM2_MOUSE Glutathione S-transferase Mu 2 195 25700 6.9 17 8 11 6 8 0.6 1.62
MPRI_MOUSE Cation-independent mannose-6-phosphate receptor 309 273639 5.47 30 18 23 16 23 0.18 0.28
CALX_MOUSE Calnexin 307 67236 4.5 23 15 16 9 16 0.37 0.86
EIF3D_MOUSE Eukaryotic translation initiation factor 3 subunit D 305 63948 5.79 11 8 7 5 7 0.25 0.39
TPM4_MOUSE Tropomyosin alpha-4 chain 203 28450 4.65 21 9 11 7 10 0.46 1.77
CATZ_MOUSE Cathepsin Z 303 33974 6.13 11 9 4 4 4 0.26 0.63
GNAI2_MOUSE Guanine nucleotide-binding protein G(i) subunit alpha-2 255 40463 5.28 19 9 11 6 5 0.38 0.85
STOM_MOUSE Erythrocyte band 7 integral membrane protein 300 31355 6.45 18 10 7 5 7 0.38 0.94
ITB1_MOUSE Integrin beta-1 300 88173 5.68 29 17 18 10 18 0.41 0.61
PSA7_MOUSE Proteasome subunit alpha type-7 296 27838 8.59 15 6 8 4 8 0.48 0.81
KCRB_MOUSE Creatine kinase B-type 295 42686 5.4 17 12 10 6 10 0.52 0.79
COPB_MOUSE Coatomer subunit beta 295 106998 5.69 16 11 14 10 14 0.23 0.48
LEG1_MOUSE Galectin-1 294 14856 5.32 28 14 9 6 9 0.75 8.03
ANXA2_MOUSE Annexin A2 293 38652 7.55 24 19 14 11 14 0.49 2.27
XPO2_MOUSE Exportin-2 289 110384 5.52 10 9 6 5 6 0.12 0.26
EF1D_MOUSE Elongation factor 1-delta 289 31274 4.91 22 11 11 7 10 0.5 1.53
EF1B_MOUSE Elongation factor 1-beta 205 24678 4.53 16 9 6 6 5 0.42 1.74
PAI1_MOUSE Plasminogen activator inhibitor 1 288 45141 6.17 20 10 13 7 13 0.49 0.91
APT_MOUSE Adenine phosphoribosyltransferase 287 19712 6.31 10 8 6 5 6 0.51 1.84
AKA12_MOUSE A-kinase anchor protein 12 286 180586 4.39 36 13 22 8 22 0.26 0.2
IMA4_MOUSE Importin subunit alpha-4 85 57737 4.8 7 4 5 3 2 0.22 0.24
SERA_MOUSE D-3-Phosphoglycerate dehydrogenase 283 56549 6.12 21 14 14 9 14 0.34 0.94
SND1_MOUSE Staphylococcal nuclease domain-containing protein 1 282 102025 7.08 25 19 12 10 12 0.26 0.57
ITA5_MOUSE Integrin alpha-5 280 114971 5.65 23 14 13 9 13 0.2 0.44
RRBP1_MOUSE Ribosome-binding protein 1 280 172776 9.35 42 16 28 9 28 0.24 0.24
PSB4_MOUSE Proteasome subunit beta type-4 280 29097 5.47 9 5 7 3 7 0.45 0.53
NUCL_MOUSE Nucleolin 278 76677 4.69 14 11 10 8 10 0.2 0.55
SFXN3_MOUSE Sideroflexin-3 277 35384 9.58 12 7 7 3 7 0.4 0.42
ADK_MOUSE Adenosine kinase 276 40123 5.84 12 11 7 6 7 0.35 0.86
HNRPU_MOUSE Heterogeneous nuclear ribonucleoprotein U 275 87863 5.92 25 15 17 12 17 0.27 0.77
HXK3_MOUSE Hexokinase-3 270 100037 5.63 20 12 13 7 13 0.26 0.34
PGM1_MOUSE Phosphoglucomutase-1 270 61380 6.14 15 11 8 6 8 0.27 0.61
PSB2_MOUSE Proteasome subunit beta type-2 269 22892 6.52 24 14 10 5 10 0.64 1.95
ICAL_MOUSE Calpastatin 269 84871 5.37 10 7 5 4 5 0.15 0.22
CD81_MOUSE CD81 antigen 268 25797 5.54 5 5 2 2 2 0.18 0.62
PPCE_MOUSE Prolyl endopeptidase 267 80700 5.44 17 8 12 5 12 0.31 0.3
PEBP1_MOUSE Phosphatidylethanolamine-binding protein 1 267 20817 5.19 16 11 9 7 9 0.78 2.99
MRC2_MOUSE C-type mannose receptor 2 265 166968 5.65 18 11 14 8 14 0.19 0.22
AP2A2_MOUSE AP-2 complex subunit alpha-2 264 103951 6.51 24 11 16 7 10 0.28 0.33
AP2A1_MOUSE AP-2 complex subunit alpha-1 140 107596 6.63 18 7 17 6 11 0.31 0.26
DDB1_MOUSE DNA damage-binding protein 1 262 126772 5.14 19 11 9 4 9 0.16 0.18
ITAV_MOUSE Integrin alpha-V 262 115287 5.41 28 10 15 5 15 0.18 0.2
CH10_MOUSE 10 kDa heat shock protein, mitochondrial 260 10956 7.93 18 10 5 2 5 0.52 1.09
COMT_MOUSE Catechol O-methyltransferase 258 29467 5.52 8 6 4 2 4 0.29 0.33
DDX3X_MOUSE ATP-dependent RNA helicase DDX3X 257 73056 6.73 21 11 14 8 14 0.36 0.58
PSB7_MOUSE Proteasome subunit beta type-7 257 29872 8.14 8 6 5 3 5 0.32 0.52
PNPH_MOUSE Purine nucleoside phosphorylase 257 32256 5.78 17 10 11 9 11 0.67 2.18
PCNA_MOUSE Proliferating cell nuclear antigen 256 28766 4.66 15 10 9 5 9 0.66 1.06
SYSC_MOUSE Serine–tRNA ligase, cytoplasmic 255 58352 5.95 17 12 13 8 13 0.41 0.77
AATM_MOUSE Aspartate aminotransferase, mitochondrial 255 47381 9.13 32 14 18 10 18 0.54 1.41
RL3_MOUSE 60S ribosomal protein L3 254 46081 10.22 30 20 11 8 11 0.36 1.26
FUMH_MOUSE Fumarate hydratase, mitochondrial 254 54322 9.12 10 8 8 6 8 0.36 0.59
MAP4_MOUSE Microtubule-associated protein 4 254 117357 4.9 24 13 14 8 14 0.23 0.33
MAP1B_MOUSE Microtubule-associated protein 1B 254 270089 4.76 14 8 9 3 9 0.06 0.05
SEC13_MOUSE Protein SEC13 homolog 253 35543 5.15 10 6 4 3 4 0.19 0.42
LAMP1_MOUSE Lysosome-associated membrane glycoprotein 1 253 43837 8.66 23 14 8 4 8 0.35 0.61
FBLN2_MOUSE Fibulin-2 253 131746 4.58 27 12 17 9 17 0.23 0.33
GORS2_MOUSE Golgi reassembly-stacking protein 2 252 47009 4.68 10 8 4 4 4 0.15 0.56
PSB6_MOUSE Proteasome subunit beta type-6 250 25362 4.97 14 10 9 7 9 0.67 2.14
SERC_MOUSE Phosphoserine aminotransferase 249 40447 8.15 26 13 13 8 13 0.55 1.28
ERP29_MOUSE Endoplasmic reticulum resident protein 29 248 28805 5.9 22 13 9 6 9 0.5 1.37
EHD1_MOUSE EH domain-containing protein 1 247 60565 6.35 22 9 15 9 15 0.47 0.86
RCN3_MOUSE Reticulocalbin-3 246 37978 4.74 7 6 4 4 4 0.27 0.55
COPE_MOUSE Coatomer subunit epsilon 245 34545 4.94 10 7 7 6 7 0.38 1.06
PSME1_MOUSE Proteasome activator complex subunit 1 244 28655 5.73 13 12 5 4 5 0.34 0.78
TADBP_MOUSE TAR DNA-binding protein 43 244 44519 6.26 9 9 7 7 7 0.34 0.92
C1QBP_MOUSE Complement component 1 Q subcomponent-binding Protein, mitochondrial 206 30994 4.82 11 7 7 4 1 0.45 0.71
PUR9_MOUSE Bifunctional purine biosynthesis protein PURH 242 64177 6.3 27 14 18 12 13 0.52 1.18
RCN2_MOUSE Reticulocalbin-2 242 37248 4.28 10 8 7 5 7 0.39 0.75
PPIB_MOUSE Peptidyl-prolyl cis-trans isomerase B 241 23699 9.56 20 9 12 4 12 0.54 1.39
PPIC_MOUSE Peptidyl-prolyl cis-trans isomerase C 140 22780 6.96 5 5 4 4 4 0.26 1.07
RLA1_MOUSE 60S acidic ribosomal protein P1 240 11468 4.28 6 6 3 3 3 0.53 1.9
SNAA_MOUSE Alpha-soluble NSF attachment protein 239 33168 5.3 15 11 11 8 11 0.56 1.72
KAD2_MOUSE Adenylate kinase 2, mitochondrial 239 26452 6.96 8 6 5 4 5 0.3 0.87
GDIR1_MOUSE Rho GDP-dissociation inhibitor 1 238 23393 5.12 16 12 10 8 10 0.51 3.1
CNN2_MOUSE Calponin-2 237 33134 7.53 20 7 11 5 4 0.65 0.87
SNX9_MOUSE Sorting nexin-9 236 66504 5.35 17 10 11 6 11 0.36 0.46
CO3A1_MOUSE Collagen alpha-1(III) chain 236 138858 6.11 28 13 12 6 8 0.15 0.23
IMA5_MOUSE Importin subunit alpha-5 195 60144 4.93 8 7 4 3 3 0.18 0.32
AMPL_MOUSE Cytosol aminopeptidase 234 56106 7.62 22 11 13 10 13 0.4 1.1
PABP1_MOUSE Polyadenylate-binding protein 1 233 70626 9.52 19 10 16 8 16 0.32 0.7
SPA3N_MOUSE Serine protease inhibitor A3N 233 46688 5.59 4 4 3 3 3 0.13 0.31
GARS_MOUSE Glycine–tRNA ligase 233 81826 6.24 15 8 12 6 12 0.33 0.36
AP1B1_MOUSE AP-1 complex subunit beta-1 231 103869 5.04 17 11 13 8 9 0.26 0.44
NP1L1_MOUSE Nucleosome assembly protein 1-like 1 231 45317 4.36 19 10 12 6 3 0.5 0.9
MTPN_MOUSE Myotrophin 227 12853 5.27 12 7 6 4 6 0.68 2.55
GRN_MOUSE Granulins 227 63413 6.42 21 15 5 4 5 0.14 0.3
CTNA1_MOUSE Catenin alpha-1 226 100044 5.91 14 10 9 7 9 0.19 0.34
ECHM_MOUSE Enoyl-CoA hydratase, mitochondrial 226 31454 8.76 10 9 6 5 6 0.29 1.21
ITB2_MOUSE Integrin beta-2 226 84970 7.02 15 8 8 5 8 0.17 0.28
LKHA4_MOUSE Leukotriene A-4 hydrolase 226 69007 5.98 13 10 7 6 7 0.21 0.44
MYADM_MOUSE Myeloid-associated differentiation marker 225 35261 8.69 18 10 4 3 4 0.19 0.42
ARC1B_MOUSE Actin-related protein 2/3 complex subunit 1B 224 41037 8.69 12 9 8 6 8 0.38 0.84
COPD_MOUSE Coatomer subunit delta 222 57193 5.89 28 14 12 6 12 0.33 0.55
DUS3_MOUSE Dual specificity protein phosphatase 3 222 20459 6.07 6 4 5 4 5 0.46 1.24
SYEP_MOUSE Bifunctional glutamate/proline–tRNA ligase 222 169972 7.75 29 11 21 8 21 0.24 0.22
SC23A_MOUSE Protein transport protein Sec23A 221 86106 6.64 28 14 18 8 17 0.46 0.55
NDUS1_MOUSE NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 220 79726 5.51 12 6 9 5 9 0.22 0.37
DDX1_MOUSE ATP-dependent RNA helicase DDX1 220 82448 6.8 16 10 9 4 9 0.16 0.22
SYVC_MOUSE Valine–tRNA ligase 220 140127 7.9 26 20 15 13 15 0.24 0.52
RS3A_MOUSE 40S ribosomal protein S3a 219 29866 9.75 31 11 17 9 17 0.55 2.49
PLOD3_MOUSE Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 216 84869 5.81 23 14 14 8 14 0.32 0.48
F10A1_MOUSE Hsc70-interacting protein 216 41630 5.19 10 7 4 3 4 0.15 0.35
LYZ2_MOUSE Lysozyme C-2 214 16678 9.11 15 6 8 4 8 0.63 3.39
MIF_MOUSE Macrophage migration inhibitory factor 214 12496 6.79 12 8 6 4 6 0.6 4.07
DEST_MOUSE Destrin 214 18509 8.14 13 10 10 7 10 0.62 4.9
HCD2_MOUSE 3-Hydroxyacyl-CoA dehydrogenase type-2 214 27402 8.53 11 7 6 4 6 0.39 0.83
DNJA2_MOUSE DnaJ homolog subfamily A member 2 213 45717 6.06 7 7 3 3 3 0.18 0.31
MARCS_MOUSE Myristoylated alanine-rich C-kinase substrate 213 29644 4.34 13 9 3 3 3 0.27 0.52
LICH_MOUSE Lysosomal acid lipase/cholesteryl ester hydrolase 212 45296 8.16 11 10 6 6 6 0.29 0.9
SAE2_MOUSE SUMO-activating enzyme subunit 2 211 70525 5.09 9 8 5 4 5 0.2 0.27
RL6_MOUSE 60S ribosomal protein L6 210 33489 10.69 17 8 10 5 10 0.37 0.86
FKB10_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP10 208 64656 5.38 21 8 12 6 12 0.3 0.47
IPO4_MOUSE Importin-4 208 119198 4.92 15 7 12 6 12 0.19 0.23
RL14_MOUSE 60S ribosomal protein L14 206 23549 11.03 12 6 6 2 6 0.33 0.42
PLD3_MOUSE Phospholipase D3 205 54354 6.07 15 10 9 7 9 0.37 0.85
LRC59_MOUSE Leucine-rich repeat-containing protein 59 205 34856 9.57 15 5 9 3 9 0.35 0.43
NIBAN_MOUSE Protein Niban 204 102585 4.72 15 10 9 6 9 0.17 0.28
CATK_MOUSE Cathepsin K 203 36865 8.61 5 4 4 3 4 0.25 0.4
HMCS1_MOUSE Hydroxymethylglutaryl-CoA synthase, cytoplasmic 201 57532 5.65 17 10 12 6 12 0.39 0.66
GANAB_MOUSE Neutral alpha-glucosidase AB 201 106844 5.67 16 11 12 9 12 0.24 0.42
PSB5_MOUSE Proteasome subunit beta type-5 200 28514 6.52 10 7 7 4 7 0.36 0.79
LEG3_MOUSE Galectin-3 200 27498 8.46 27 10 14 6 14 0.42 1.47
SYNC_MOUSE Asparagine–tRNA ligase, cytoplasmic 197 64238 5.62 19 11 15 9 15 0.41 0.79
DCTN2_MOUSE Dynactin subunit 2 197 44090 5.14 8 5 8 5 8 0.34 0.6
ZYX_MOUSE Zyxin 197 60507 5.99 15 7 7 3 7 0.22 0.23
LTOR3_MOUSE Ragulator complex protein LAMTOR3 195 13544 6.73 7 7 4 4 4 0.63 2.34
S10AB_MOUSE Protein S100-A11 195 11075 5.28 8 6 4 3 4 0.77 3.32
VATL_MOUSE V-type proton ATPase 16 kDa proteolipid subunit 195 15798 9.1 4 3 2 1 2 0.32 0.68
VMA5A_MOUSE von Willebrand factor A domain-containing protein 5A 194 87087 6.15 10 5 9 4 9 0.23 0.21
IBP7_MOUSE Insulin-like growth factor-binding protein 7 194 28951 8.71 16 7 8 3 8 0.46 0.54
EIF3H_MOUSE Eukaryotic translation initiation factor 3 subunit H 192 39807 6.2 8 7 6 5 6 0.34 0.68
FHL2_MOUSE Four and a half LIM domains protein 2 192 32051 7.31 14 6 6 3 6 0.28 0.47
PRS6B_MOUSE 26S proteasome regulatory subunit 6B 192 47379 5.09 9 5 8 4 8 0.4 0.42
ETFA_MOUSE Electron transfer flavoprotein subunit alpha, mitochondrial 190 34988 8.62 17 8 8 5 7 0.47 0.81
CSF1_MOUSE Macrophage colony-stimulating factor 1 190 60611 5.1 9 7 4 3 4 0.13 0.32
P4HA2_MOUSE Prolyl 4-hydroxylase subunit alpha-2 189 60964 5.55 24 10 12 9 12 0.35 0.85
LAMB1_MOUSE Laminin subunit beta-1 188 196961 4.82 17 5 12 3 12 0.12 0.07
TCPG_MOUSE T-complex protein 1 subunit gamma 188 60591 6.28 25 8 17 6 17 0.42 0.51
SQSTM_MOUSE Sequestosome-1 186 48132 5.09 10 7 6 4 6 0.28 0.41
DC1I2_MOUSE Cytoplasmic dynein 1 intermediate chain 2 185 68352 5.16 5 4 4 3 4 0.19 0.2
CATA_MOUSE Catalase 184 59758 7.72 15 6 11 4 11 0.35 0.32
VATC1_MOUSE V-type proton ATPase subunit C 1 183 43860 7.02 8 5 5 3 5 0.25 0.33
ECHB_MOUSE Trifunctional enzyme subunit beta, mitochondrial 183 51353 9.43 10 6 8 5 8 0.32 0.5
STIP1_MOUSE Stress-induced phosphoprotein 1 183 62542 6.4 15 6 11 4 11 0.35 0.31
THY1_MOUSE Thy-1 membrane glycoprotein 182 18069 9.16 14 8 5 2 5 0.49 0.58
PYRG1_MOUSE CTP synthase 1 182 66640 6.14 17 10 11 7 11 0.33 0.65
GSTO1_MOUSE Glutathione S-transferase omega-1 181 27480 6.92 36 11 19 7 19 0.83 1.87
HNRPM_MOUSE Heterogeneous nuclear ribonucleoprotein M 180 77597 8.8 16 8 11 6 11 0.23 0.38
PCOC1_MOUSE Procollagen C-endopeptidase enhancer 1 180 50136 8.73 14 6 9 4 9 0.38 0.39
ATPO_MOUSE ATP synthase subunit O, mitochondrial 180 23349 10 10 7 6 5 6 0.38 1.43
IDH3A_MOUSE Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 179 39613 6.27 9 5 4 1 4 0.15 0.23
POSTN_MOUSE Periostin 179 93085 7.27 15 7 10 4 10 0.25 0.2
HCDH_MOUSE Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial 179 34442 8.76 10 6 6 4 6 0.5 0.62
DHB4_MOUSE Peroxisomal multifunctional enzyme type 2 179 79432 8.76 22 13 13 8 13 0.24 0.52
PTGIS_MOUSE Prostacyclin synthase 178 57011 6.26 21 9 18 8 18 0.53 0.79
TPP1_MOUSE Tripeptidyl-peptidase 1 177 61304 6.1 8 7 6 5 6 0.21 0.5
SAE1_MOUSE SUMO-activating enzyme subunit 1 177 38596 5.24 7 5 5 3 5 0.24 0.38
6PGL_MOUSE 6-Phosphogluconolactonase 177 27237 5.55 9 6 5 2 5 0.35 0.36
SUCB1_MOUSE Succinate–CoA ligase [ADP-forming] subunit beta, mitochondrial 176 50082 6.57 8 5 6 3 6 0.27 0.28
IDI1_MOUSE Isopentenyl-diphosphate delta-isomerase 1 175 26272 5.79 14 5 6 4 6 0.49 0.88
PLIN3_MOUSE Perilipin-3 175 47233 5.45 12 9 10 8 10 0.43 1.02
RL7_MOUSE 60S ribosomal protein L7 174 31400 10.89 19 9 13 5 13 0.46 0.93
RAB1B_MOUSE Ras-related protein Rab-1B 130 22173 5.55 15 7 10 5 4 0.52 1.53
FERM2_MOUSE Fermitin family homolog 2 174 77750 6.26 9 4 6 3 6 0.18 0.18
CAZA2_MOUSE F-actin-capping protein subunit alpha-2 173 32947 5.57 19 10 11 7 4 0.65 1.41
CAZA1_MOUSE F-actin-capping protein subunit alpha-1 61 32919 5.34 9 3 7 3 5 0.44 0.46
EIF3K_MOUSE Eukaryotic translation initiation factor 3 subunit K 173 25070 4.81 10 3 8 2 8 0.61 0.39
G6PD1_MOUSE Glucose-6-phosphate 1-dehydrogenase X 172 59225 6.06 22 11 14 7 14 0.4 0.64
ASAH1_MOUSE Acid ceramidase 172 44641 8.68 10 7 9 6 9 0.3 0.75
ADHX_MOUSE Alcohol dehydrogenase class-3 172 39522 6.97 14 7 9 7 9 0.51 1.09
IF4G1_MOUSE Eukaryotic translation initiation factor 4 gamma 1 172 175967 5.3 16 10 11 7 11 0.11 0.18
IL6RB_MOUSE Interleukin-6 receptor subunit beta 171 102387 5.35 14 8 4 2 4 0.06 0.09
NMT1_MOUSE Glycylpeptide N-tetradecanoyltransferase 1 171 56852 8.04 8 5 6 3 6 0.24 0.25
ANXA4_MOUSE Annexin A4 170 35893 5.43 10 7 8 5 8 0.3 0.78
PCYOX_MOUSE Prenylcysteine oxidase 169 56459 6.44 8 5 7 4 7 0.24 0.34
BASP1_MOUSE Brain acid soluble protein 1 168 22074 4.5 21 9 5 3 5 0.42 0.75
PSMD5_MOUSE 26S proteasome non-ATPase regulatory subunit 5 168 55937 5.13 10 5 7 3 7 0.28 0.25
IPYR_MOUSE Inorganic pyrophosphatase 165 32646 5.37 6 4 4 2 4 0.26 0.29
ISG15_MOUSE Ubiquitin-like protein ISG15 164 17886 7.74 6 5 3 2 3 0.5 0.58
ACO13_MOUSE Acyl-coenzyme A thioesterase 13 164 15173 8.95 8 7 5 5 5 0.56 2.84
CP51A_MOUSE Lanosterol 14-alpha demethylase 164 56739 8.6 12 4 8 3 5 0.3 0.25
IMPA1_MOUSE Inositol monophosphatase 1 163 30416 5.08 13 4 5 2 5 0.21 0.31
P3H1_MOUSE Prolyl 3-hydroxylase 1 162 83598 5.03 12 6 8 4 8 0.22 0.22
SDHA_MOUSE Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 161 72539 7.06 12 9 5 4 5 0.15 0.26
VPS25_MOUSE Vacuolar protein-sorting-associated protein 25 161 20735 5.97 4 4 1 1 1 0.19 0.49
PHB_MOUSE Prohibitin 159 29802 5.57 17 10 11 7 11 0.65 1.65
PSA6_MOUSE Proteasome subunit alpha type-6 158 27355 6.34 14 5 8 3 8 0.52 0.58
TOM40_MOUSE Mitochondrial import receptor subunit TOM40 homolog 156 37871 7.64 10 8 6 4 6 0.32 0.73
UBP5_MOUSE Ubiquitin carboxyl-terminal hydrolase 5 156 95772 4.89 18 10 10 7 10 0.23 0.36
EFTU_MOUSE Elongation factor Tu, mitochondrial 156 49477 7.23 16 5 12 3 11 0.44 0.29
DHB7_MOUSE 3-Keto-steroid reductase 154 37293 6.25 9 5 6 4 6 0.26 0.75
CAVN1_MOUSE Caveolae-associated protein 1 153 43927 5.43 7 6 3 2 3 0.15 0.21
ODPB_MOUSE Pyruvate dehydrogenase E1 component subunit beta, mitochondrial 152 38912 6.41 14 7 6 4 6 0.32 0.53
DNPEP_MOUSE Aspartyl aminopeptidase 152 52174 6.82 18 12 10 7 10 0.41 0.75
PRDX5_MOUSE Peroxiredoxin-5, mitochondrial 151 21884 9.1 20 5 10 4 10 0.54 1.13
ARPC2_MOUSE Actin-related protein 2/3 complex subunit 2 150 34336 6.84 13 4 10 2 10 0.39 0.27
PCKGM_MOUSE Phosphoenolpyruvate carboxykinase [GTP], mitochondrial 150 70482 6.92 4 3 3 2 3 0.08 0.13
GLCM_MOUSE Glucosylceramidase 150 57585 7.64 14 10 10 8 10 0.37 0.78
NB5R1_MOUSE NADH-cytochrome b5 reductase 1 150 34113 8.97 4 3 4 3 4 0.26 0.44
PUR6_MOUSE Multifunctional protein ADE2 149 46976 6.94 11 6 8 5 8 0.37 0.56
LPPRC_MOUSE Leucine-rich PPR motif-containing protein, mitochondrial 149 156516 6.42 18 4 14 4 14 0.16 0.11
SAC1_MOUSE Phosphatidylinositide phosphatase SAC1 148 66901 6.85 9 4 4 2 4 0.12 0.13
GFPT2_MOUSE Glutamine–fructose-6-phosphate aminotransferase [isomerizing] 2 147 76960 6.72 10 4 9 4 9 0.21 0.24
MTAP_MOUSE S-Methyl-5 -thioadenosine phosphorylase 146 31042 6.71 7 4 5 3 5 0.29 0.49
IKIP_MOUSE Inhibitor of nuclear factor kappa-B kinase-interacting protein 146 42505 5.03 13 10 4 2 4 0.29 0.22
ADPGK_MOUSE ADP-dependent glucokinase 146 53869 5.37 9 7 4 3 4 0.15 0.26
MA2A1_MOUSE Alpha-mannosidase 2 145 131548 8.17 12 7 10 6 10 0.15 0.21
SYLC_MOUSE Leucine–tRNA ligase, cytoplasmic 145 134106 6.64 13 6 10 4 10 0.16 0.13
SYIC_MOUSE Isoleucine–tRNA ligase, cytoplasmic 145 144179 6.14 18 8 12 5 12 0.19 0.16
PARVA_MOUSE Alpha-parvin 144 42304 5.69 9 5 5 3 5 0.26 0.34
DYN2_MOUSE Dynamin-2 144 98084 7.02 12 5 9 3 7 0.19 0.14
IMA1_MOUSE Importin subunit alpha-1 144 57892 5.49 13 4 8 3 8 0.27 0.24
CYGB_MOUSE Cytoglobin 144 21452 6.32 8 4 3 2 3 0.33 0.47
ODO1_MOUSE 2-Oxoglutarate dehydrogenase, mitochondrial 143 116375 6.36 34 6 9 4 9 0.14 0.15
MK01_MOUSE Mitogen-activated protein kinase 1 143 41249 6.5 8 5 7 4 7 0.38 0.5
UD17C_MOUSE UDP-glucuronosyltransferase 1-7C 143 59719 8.64 14 5 8 3 8 0.27 0.23
HMOX1_MOUSE Heme oxygenase 1 142 32908 6.08 16 7 10 6 10 0.57 1.13
USO1_MOUSE General vesicular transport factor p115 142 106917 4.85 11 7 10 6 10 0.17 0.26
RTN4_MOUSE Reticulon-4 142 126535 4.47 23 9 10 5 10 0.16 0.18
THIKA_MOUSE 3-Ketoacyl-CoA thiolase A, peroxisomal 141 43926 8.74 14 8 10 5 10 0.47 0.61
MGST1_MOUSE Microsomal glutathione S-transferase 1 141 17540 9.67 6 5 2 2 2 0.22 0.6
HYEP_MOUSE Epoxide hydrolase 1 141 52543 8.43 18 5 14 4 14 0.41 0.37
GUAD_MOUSE Guanine deaminase 141 50981 5.36 6 5 4 3 4 0.24 0.28
LASP1_MOUSE LIM and SH3 domain protein 1 140 29975 6.61 23 7 7 2 7 0.29 0.51
4F2_MOUSE 4F2 cell-surface antigen heavy chain 139 58300 5.62 12 8 7 5 7 0.26 0.43
PPAC_MOUSE Low molecular weight phosphotyrosine protein phosphatase 139 18180 6.3 6 3 4 3 4 0.45 0.97
CD36_MOUSE Platelet glycoprotein 4 139 52664 8.6 6 5 6 5 6 0.19 0.49
ATPG_MOUSE ATP synthase subunit gamma, mitochondrial 139 32865 9.06 9 6 6 3 6 0.3 0.46
AL9A1_MOUSE 4-Trimethylaminobutyraldehyde dehydrogenase 138 53480 6.63 7 6 4 3 4 0.18 0.26
ASPH_MOUSE Aspartyl/asparaginyl beta-hydroxylase 138 82991 4.97 6 4 5 3 5 0.1 0.16
ATPD_MOUSE ATP synthase subunit delta, mitochondrial 138 17589 5.03 14 9 5 2 5 0.63 0.6
IRGM1_MOUSE Immunity-related GTPase family M protein 1 137 46522 8.56 7 5 4 4 4 0.2 0.43
PON3_MOUSE Serum paraoxonase/lactonase 3 137 39326 5.44 9 5 5 4 5 0.26 0.53
UMPS_MOUSE Uridine 5 -monophosphate synthase 137 52259 6.17 7 5 6 4 6 0.23 0.38
CMTD1_MOUSE Catechol O-methyltransferase domain-containing protein 1 137 28943 8.61 7 4 6 3 6 0.51 0.54
SYUG_MOUSE Gamma-synuclein 137 13152 4.68 6 5 3 3 3 0.4 1.54
CLIC4_MOUSE Chloride intracellular channel protein 4 137 28711 5.44 10 7 8 5 7 0.41 1.06
CRIP2_MOUSE Cysteine-rich protein 2 136 22712 8.94 8 5 3 3 3 0.34 1.07
PLOD1_MOUSE Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 136 83542 6.08 12 5 10 4 10 0.2 0.22
CPNE1_MOUSE Copine-1 136 58849 5.4 7 4 5 3 5 0.18 0.24
RL4_MOUSE 60S ribosomal protein L4 136 47124 11.01 40 10 20 9 20 0.45 1.21
RN213_MOUSE E3 ubiquitin-protein ligase RNF213 135 584411 6.35 29 8 22 6 22 0.09 0.04
CD109_MOUSE CD109 antigen 134 161557 5.37 5 5 4 4 4 0.05 0.11
LAMP2_MOUSE Lysosome-associated membrane glycoprotein 2 134 45652 7.05 11 4 7 3 7 0.16 0.31
ARL8A_MOUSE ADP-ribosylation factor-like protein 8A 134 21376 7.63 14 8 6 4 6 0.4 1.16
NCEH1_MOUSE Neutral cholesterol ester hydrolase 1 133 45711 6.56 12 7 7 4 7 0.34 0.44
GNPI1_MOUSE Glucosamine-6-phosphate isomerase 1 133 32528 6.13 8 5 7 4 7 0.36 0.67
NOMO1_MOUSE Nodal modulator 1 133 133336 5.75 13 8 10 7 10 0.19 0.25
RRAS_MOUSE Ras-related protein R-Ras 133 23749 6.32 6 4 4 3 2 0.23 0.68
RCN1_MOUSE Reticulocalbin-1 133 38090 4.7 12 6 6 4 6 0.25 0.55
PFKAP_MOUSE ATP-dependent 6-phosphofructokinase, platelet type 132 85400 6.73 12 4 9 2 9 0.24 0.1
BLVRB_MOUSE Flavin reductase (NADPH) 132 22183 6.49 15 6 9 5 9 0.69 1.53
TMM43_MOUSE Transmembrane protein 43 132 44755 6.85 6 5 6 5 6 0.31 0.59
P5CS_MOUSE Delta-1-pyrroline-5-carboxylate synthase 131 87212 7.18 12 5 9 4 9 0.19 0.21
MATR3_MOUSE Matrin-3 131 94572 5.87 6 4 5 3 5 0.14 0.14
PTGR1_MOUSE Prostaglandin reductase 1 131 35537 8.09 5 5 5 5 5 0.26 0.79
COTL1_MOUSE Coactosin-like protein 131 15934 5.28 10 3 6 2 6 0.55 0.67
ACAD9_MOUSE Acyl-CoA dehydrogenase family member 9, mitochondrial 131 68679 7.16 6 6 3 3 3 0.11 0.2
IFM3_MOUSE Interferon-induced transmembrane protein 3 130 14945 6.89 14 6 3 3 2 0.32 1.98
IFM2_MOUSE Interferon-induced transmembrane protein 2 59 15733 6.81 9 3 3 2 2 0.17 0.68
DHX9_MOUSE ATP-dependent RNA helicase A 130 149381 6.39 17 9 11 5 11 0.13 0.15
SDCB1_MOUSE Syntenin-1 130 32359 6.66 9 4 4 3 4 0.29 0.47
ORN_MOUSE Oligoribonuclease, mitochondrial 129 26722 6.67 8 4 6 3 6 0.38 0.59
ITM2B_MOUSE Integral membrane protein 2B 128 30240 5.14 16 7 7 5 7 0.45 0.99
EIF3I_MOUSE Eukaryotic translation initiation factor 3 subunit I 128 36438 5.38 15 6 9 5 9 0.47 0.77
FIS1_MOUSE Mitochondrial fission 1 protein 128 16998 8.56 5 4 4 3 4 0.31 1.07
SAHH_MOUSE Adenosylhomocysteinase 128 47657 6.08 15 8 11 7 11 0.43 0.84
TFR1_MOUSE Transferrin receptor protein 1 127 85677 6.13 4 4 3 3 3 0.05 0.16
STML2_MOUSE Stomatin-like protein 2, mitochondrial 127 38361 8.95 13 8 9 6 9 0.52 0.91
IF6_MOUSE Eukaryotic translation initiation factor 6 127 26494 4.63 7 6 5 4 5 0.56 1.18
VPP1_MOUSE V-type proton ATPase 116 kDa subunit a isoform 1 126 96404 6.29 10 4 7 3 7 0.13 0.14
PREP_MOUSE Presequence protease, mitochondrial 126 117297 6.76 10 6 10 6 10 0.17 0.24
BIN1_MOUSE Myc box-dependent-interacting protein 1 125 64430 4.95 16 6 10 5 10 0.32 0.38
CSN7A_MOUSE COP9 signalosome complex subunit 7a 125 30206 7.68 8 6 4 3 4 0.26 0.51
SSRD_MOUSE Translocon-associated protein subunit delta 125 18924 5.5 7 6 3 2 3 0.25 0.55
COR1B_MOUSE Coronin-1B 124 53878 5.54 15 7 7 3 7 0.29 0.26
VKOR1_MOUSE Vitamin K epoxide reductase complex subunit 1 124 17756 9.37 6 4 2 2 2 0.19 0.59
FUBP2_MOUSE Far upstream element-binding protein 2 124 76728 6.9 11 4 7 3 7 0.12 0.18
MFGM_MOUSE Lactadherin 122 51208 6.1 22 9 13 7 13 0.45 0.77
PSME2_MOUSE Proteasome activator complex subunit 2 122 27040 5.54 10 6 7 4 7 0.46 0.84
C1TC_MOUSE C-1-tetrahydrofolate synthase, cytoplasmic 122 101136 6.7 12 5 8 3 8 0.12 0.13
RISC_MOUSE Retinoid-inducible serine carboxypeptidase 122 50932 5.48 11 5 8 4 8 0.21 0.39
ETFB_MOUSE Electron transfer flavoprotein subunit beta 122 27606 8.24 16 4 8 2 8 0.43 0.35
PRRC1_MOUSE Protein PRRC1 122 46268 5.62 10 5 8 5 8 0.31 0.57
MAOM_MOUSE NAD-dependent malic enzyme, mitochondrial 121 65757 7.53 6 5 3 3 3 0.15 0.21
SH3L1_MOUSE SH3 domain-binding glutamic acid-rich-like protein 120 12803 4.87 4 3 3 2 3 0.38 0.89
PSB1_MOUSE Proteasome subunit beta type-1 120 26355 7.67 9 5 7 4 7 0.55 0.88
LY6E_MOUSE Lymphocyte antigen 6E 120 13791 6.67 4 3 2 2 2 0.29 1.44
SPRC_MOUSE SPARC 120 34428 4.77 8 5 6 4 6 0.33 0.62
ECI2_MOUSE Enoyl-CoA delta isomerase 2, mitochondrial 119 43240 9.08 9 5 4 1 4 0.16 0.1
AIMP2_MOUSE Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 119 35355 7.7 9 6 5 4 5 0.34 0.6
TOM1_MOUSE Target of Myb protein 1 119 54291 4.83 5 4 5 4 5 0.22 0.36
TALDO_MOUSE Transaldolase 119 37363 6.57 16 5 10 4 10 0.31 0.56
SAMH1_MOUSE Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 118 72604 8.17 8 4 6 2 6 0.17 0.12
LPP_MOUSE Lipoma-preferred partner homolog 118 65848 7.19 11 7 6 4 6 0.22 0.29
STX12_MOUSE Syntaxin-12 118 31176 5.33 9 5 8 4 8 0.45 0.7
CYB5B_MOUSE Cytochrome b5 type B 118 16308 4.79 5 4 4 3 4 0.51 1.13
PDLI1_MOUSE PDZ and LIM domain protein 1 117 35752 6.38 9 4 7 4 7 0.38 0.59
FABP4_MOUSE Fatty acid-binding protein, adipocyte 117 14641 8.53 6 3 5 3 5 0.47 1.31
BACH_MOUSE Cytosolic acyl coenzyme A thioester hydrolase 117 42510 8.9 6 3 5 3 5 0.24 0.34
NSF1C_MOUSE NSFL1 cofactor p47 117 40685 5.04 9 7 2 2 2 0.11 0.23
CMC1_MOUSE Calcium-binding mitochondrial carrier protein Aralar1 117 74523 8.43 8 2 7 2 7 0.18 0.12
S10A1_MOUSE Protein S100-A1 117 10498 4.37 2 2 1 1 1 0.16 0.47
ACDSB_MOUSE Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial 116 47843 8 7 4 4 2 4 0.19 0.19
CO4A1_MOUSE Collagen alpha-1(IV) chain 116 160579 8.51 16 3 8 2 8 0.13 0.08
SPEE_MOUSE Spermidine synthase 116 33973 5.31 10 4 10 4 10 0.65 0.63
EDC4_MOUSE Enhancer of mRNA-decapping protein 4 115 152389 5.51 6 4 3 2 3 0.03 0.06
SGT1_MOUSE Protein SGT1 homolog 115 38135 5.32 4 3 3 2 3 0.16 0.24
SQOR_MOUSE Sulfide:quinone oxidoreductase, mitochondrial 115 50250 9.2 6 4 4 2 4 0.12 0.18
SYWC_MOUSE Tryptophan–tRNA ligase, cytoplasmic 114 54323 6.44 9 5 7 4 7 0.26 0.36
PDXD1_MOUSE Pyridoxal-dependent decarboxylase domain-containing protein 1 114 87281 5.31 12 6 7 4 7 0.18 0.21
BROX_MOUSE BRO1 domain-containing protein BROX 114 46172 7.59 6 4 2 2 2 0.11 0.2
SCFD1_MOUSE Sec1 family domain-containing protein 1 112 72277 5.98 5 2 5 2 5 0.19 0.12
DHPR_MOUSE Dihydropteridine reductase 113 25554 7.67 4 2 2 1 2 0.11 0.18
NDUS3_MOUSE NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 113 30131 6.67 4 3 2 1 2 0.11 0.15
TAGL_MOUSE Transgelin 113 22561 8.85 12 6 8 5 8 0.51 2
PALLD_MOUSE Palladin 113 152037 5.87 11 4 9 3 9 0.11 0.09
RL18_MOUSE 60S ribosomal protein L18 112 21631 11.79 7 6 4 3 4 0.25 0.77
MPCP_MOUSE Phosphate carrier protein, mitochondrial 112 39606 9.36 39 5 9 3 9 0.28 0.37
CYFP1_MOUSE Cytoplasmic FMR1-interacting protein 1 112 145148 6.46 6 3 6 3 6 0.07 0.09
G3BP1_MOUSE Ras GTPase-activating protein-binding protein 1 112 51797 5.41 6 4 6 4 6 0.17 0.38
PYGB_MOUSE Glycogen phosphorylase, brain form 112 96668 6.28 8 3 7 2 7 0.15 0.09
S10A6_MOUSE Protein S100-A6 112 10044 5.3 12 5 6 3 6 0.66 4.05
TCTP_MOUSE Translationally-controlled tumor protein 110 19450 4.76 9 4 5 3 5 0.31 0.89
RL5_MOUSE 60S ribosomal protein L5 110 34379 9.78 12 4 9 3 9 0.43 0.44
SYHC_MOUSE Histidine–tRNA ligase, cytoplasmic 110 57396 5.79 10 5 6 4 6 0.22 0.34
CLPT1_MOUSE Cleft lip and palate transmembrane protein 1 homolog 109 75243 5.88 13 9 5 4 5 0.18 0.25
ACSF2_MOUSE Acyl-CoA synthetase family member 2, mitochondrial 109 67907 8.44 7 4 6 3 6 0.2 0.2
THIL_MOUSE Acetyl-CoA acetyltransferase, mitochondrial 108 44787 8.71 15 9 6 4 6 0.23 0.45
USMG5_MOUSE Upregulated during skeletal muscle growth protein 5 108 6377 9.84 2 2 1 1 1 0.26 0.87
ISC2A_MOUSE Isochorismatase domain-containing protein 2A 108 22403 8.25 2 2 1 1 1 0.09 0.2
HNRPL_MOUSE Heterogeneous nuclear ribonucleoprotein L 107 63923 8.33 14 6 6 2 6 0.24 0.14
PP1R7_MOUSE Protein phosphatase 1 regulatory subunit 7 106 41266 4.85 3 3 2 2 2 0.11 0.22
SE1L1_MOUSE Protein sel-1 homolog 1 106 88285 5.36 4 3 3 2 3 0.1 0.1
CCD47_MOUSE Coiled-coil domain-containing protein 47 106 55808 4.74 6 5 3 2 1 0.14 0.16
HUWE1_MOUSE E3 ubiquitin-protein ligase HUWE1 105 482332 5.1 15 2 13 1 13 0.06 0.01
GDIR2_MOUSE Rho GDP-dissociation inhibitor 2 104 22836 4.97 5 4 4 3 4 0.45 0.72
SGPL1_MOUSE Sphingosine-1-phosphate lyase 1 104 63636 9.2 12 5 8 4 8 0.29 0.3
PLIN4_MOUSE Perilipin-4 104 139328 8.81 7 4 6 3 6 0.07 0.09
UBA6_MOUSE Ubiquitin-like modifier-activating enzyme 6 104 117891 5.75 6 2 5 1 5 0.07 0.04
ARL1_MOUSE ADP-ribosylation factor-like protein 1 104 20398 5.63 8 5 6 3 6 0.57 0.83
G6PE_MOUSE GDH/6PGL endoplasmic bifunctional protein 103 88872 6.44 6 4 5 3 5 0.11 0.15
UBP14_MOUSE Ubiquitin carboxyl-terminal hydrolase 14 103 55966 5.15 8 4 7 3 7 0.25 0.25
FSTL1_MOUSE Follistatin-related protein 1 103 34532 5.58 6 2 5 1 5 0.21 0.13
PGFRB_MOUSE Platelet-derived growth factor receptor beta 103 122728 4.99 10 7 7 4 7 0.12 0.15
CD180_MOUSE CD180 antigen 103 74255 5.55 4 2 3 1 3 0.12 0.06
GLRX1_MOUSE Glutaredoxin-1 103 11863 8.67 4 3 2 1 2 0.49 0.41
GCN1_MOUSE eIF-2-alpha kinase activator GCN1 102 292834 7.14 18 5 16 3 16 0.12 0.04
PLPP3_MOUSE Phospholipid phosphatase 3 102 35193 9.25 6 4 4 2 4 0.23 0.27
NU155_MOUSE Nuclear pore complex protein Nup155 101 155019 5.77 9 4 7 2 7 0.09 0.06
ACADV_MOUSE Very-long-chain-specific acyl-CoA dehydrogenase, mitochondrial 95 70831 8.91 3 2 3 2 3 0.08 0.13
PFD5_MOUSE Prefoldin subunit 5 101 17345 5.93 8 2 5 2 5 0.43 0.61
PSA2_MOUSE Proteasome subunit alpha type-2 101 25910 6.92 9 5 8 5 8 0.52 1.22
ZWINT_MOUSE ZW10 interactor 101 28695 8.56 4 2 3 1 3 0.24 0.33
ERG7_MOUSE Lanosterol synthase 101 83088 5.96 13 4 10 4 10 0.21 0.22
EMC1_MOUSE ER membrane protein complex subunit 1 100 111535 7 12 6 11 5 11 0.19 0.21
PYC_MOUSE Pyruvate carboxylase, mitochondrial 100 129602 6.25 4 2 4 2 4 0.07 0.07
SRPRB_MOUSE Signal recognition particle receptor subunit beta 99 29561 9.34 7 5 4 2 4 0.26 0.32
CD34_MOUSE Hematopoietic progenitor cell antigen CD34 99 40957 5.2 1 1 1 1 1 0.05 0.11
AIFM1_MOUSE Apoptosis-inducing factor 1, mitochondrial 98 66724 9.23 5 3 4 3 4 0.14 0.21
3HIDH_MOUSE 3-Hydroxyisobutyrate dehydrogenase, mitochondrial 98 35417 8.37 6 3 5 2 5 0.31 0.26
ATLA3_MOUSE Atlastin-3 98 60537 5.73 7 5 5 4 5 0.18 0.32
TXTP_MOUSE Tricarboxylate transport protein, mitochondrial 98 33910 9.91 6 2 4 2 4 0.27 0.28
IF1A_MOUSE Eukaryotic translation initiation factor 1A 98 16492 5.07 8 4 3 1 3 0.21 0.28
TRI25_MOUSE E3 ubiquitin/ISG15 ligase TRIM25 98 71680 8.62 9 2 7 2 7 0.21 0.12
QCR1_MOUSE Cytochrome b-c1 complex subunit 1, mitochondrial 97 52818 5.81 11 3 6 2 6 0.26 0.17
ACACA_MOUSE Acetyl-CoA carboxylase 1 96 265088 5.97 11 6 10 5 10 0.11 0.08
DYLT1_MOUSE Dynein light chain Tctex-type 1 95 12475 5 1 1 1 1 1 0.16 0.39
ATOX1_MOUSE Copper transport protein ATOX1 95 7334 6.04 5 3 3 2 3 0.72 4.12
RENBP_MOUSE N-Acylglucosamine 2-epimerase 94 49739 5.69 4 3 3 2 3 0.13 0.18
ROAA_MOUSE Heterogeneous nuclear ribonucleoprotein A/B 94 30812 7.68 15 6 7 5 6 0.29 0.96
GNS_MOUSE N-Acetylglucosamine-6-sulfatase 94 61136 8.52 13 5 8 3 8 0.22 0.23
TMX1_MOUSE Thioredoxin-related transmembrane protein 1 93 31376 5.19 3 3 1 1 1 0.04 0.14
OCAD1_MOUSE OCIA domain-containing protein 1 90 27593 7.66 4 3 3 2 3 0.2 0.35
STS_MOUSE Steryl-sulfatase 93 66549 8.83 2 2 1 1 1 0.03 0.06
TIF1B_MOUSE Transcription intermediary factor 1-beta 93 88791 5.52 11 4 7 4 7 0.12 0.21
LMAN2_MOUSE Vesicular integral-membrane protein VIP36 92 40404 6.46 10 4 8 3 8 0.32 0.36
SH3L3_MOUSE SH3 domain-binding glutamic acid-rich-like protein 3 92 10470 5.02 10 6 4 2 4 0.68 3.72
PTGR3_MOUSE Prostaglandin reductase-3 92 40503 7.01 4 3 4 3 4 0.25 0.36
KIME_MOUSE Mevalonate kinase 91 41851 6.22 5 2 5 2 5 0.3 0.22
PAPS2_MOUSE Bifunctional 3 -phosphoadenosine 5 -phosphosulfate synthase 2 91 70306 7.31 8 3 7 3 7 0.24 0.2
PGRC1_MOUSE Membrane-associated progesterone receptor component 1 91 21681 4.57 8 5 4 3 4 0.4 0.77
FRIH_MOUSE Ferritin heavy chain 90 21053 5.53 16 6 9 4 9 0.73 1.19
THIM_MOUSE 3-Ketoacyl-CoA thiolase, mitochondrial 90 41803 8.33 13 8 8 4 8 0.34 0.49
LGMN_MOUSE Legumain 90 49341 5.92 6 3 5 2 5 0.22 0.18
CD9_MOUSE CD9 antigen 90 25241 6.88 4 3 1 1 1 0.11 0.39
HEBP1_MOUSE Heme-binding protein 1 90 21053 5.18 2 1 2 1 2 0.29 0.22
SCPDL_MOUSE Saccharopine dehydrogenase-like oxidoreductase 90 47099 8.86 4 4 2 2 2 0.13 0.19
TOIP1_MOUSE Torsin-1A-interacting protein 1 90 66740 6.58 2 1 2 1 2 0.04 0.06
ACADL_MOUSE Long-chain specific acyl-CoA dehydrogenase, mitochondrial 89 47877 8.53 15 5 8 4 8 0.35 0.42
PTGES_MOUSE Prostaglandin E synthase 89 17274 9.47 2 2 1 1 1 0.17 0.27
PSA1_MOUSE Proteasome subunit alpha type-1 89 29528 6 11 5 7 4 7 0.32 0.75
DX39A_MOUSE ATP-dependent RNA helicase DDX39A 89 49036 5.46 5 2 5 2 5 0.23 0.19
ATP5H_MOUSE ATP synthase subunit d, mitochondrial 89 18738 5.52 7 4 6 3 6 0.55 0.93
CNPY2_MOUSE Protein canopy homolog 2 88 20754 4.95 8 5 3 2 3 0.28 0.49
AACS_MOUSE Acetoacetyl-CoA synthetase 88 75152 6.25 15 5 11 5 11 0.28 0.32
GNAS1_MOUSE Guanine nucleotide-binding protein G(s) subunit alpha isoforms Xlas 88 121429 4.72 15 5 8 3 7 0.11 0.11
HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain 88 40810 6.28 13 2 8 2 8 0.29 0.23
GNA11_MOUSE Guanine nucleotide-binding protein subunit alpha-11 88 41997 5.7 7 4 5 3 2 0.22 0.35
VATG1_MOUSE V-type proton ATPase subunit G 1 88 13716 7.77 4 3 2 1 2 0.24 0.35
NDUS5_MOUSE NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 87 12639 9.1 1 1 1 1 1 0.11 0.38
SYFB_MOUSE Phenylalanine–tRNA ligase beta subunit 87 65655 6.69 8 3 8 3 8 0.21 0.21
THOP1_MOUSE Thimet oligopeptidase 87 77976 5.72 3 3 2 2 2 0.04 0.11
HSPB1_MOUSE Heat shock protein beta-1 86 23000 6.12 9 2 7 2 7 0.56 0.43
IF2G_MOUSE Eukaryotic translation initiation factor 2 subunit 3, X-linked 86 51033 8.66 15 5 10 5 10 0.3 0.5
PDIA5_MOUSE Protein disulfide-isomerase A5 86 59229 7.25 6 2 5 1 5 0.22 0.15
BAG3_MOUSE BAG family molecular chaperone regulator 3 86 61822 6.78 12 4 7 3 7 0.23 0.22
MRGRF_MOUSE Mas-related G-protein coupled receptor member F 86 38497 9 2 2 1 1 1 0.06 0.11
SET_MOUSE Protein SET 85 33358 4.22 10 3 7 3 7 0.37 0.45
GLTP_MOUSE Glycolipid transfer protein 85 23674 6.9 2 2 2 2 2 0.2 0.42
DPP3_MOUSE Dipeptidyl peptidase 3 85 82846 5.26 6 3 4 1 4 0.12 0.05
CARM1_MOUSE Histone-arginine methyltransferase CARM1 85 65811 6.28 5 3 4 3 4 0.12 0.21
SERC1_MOUSE Serine incorporator 1 85 50475 5.91 3 2 2 1 2 0.06 0.09
DCUP_MOUSE Uroporphyrinogen decarboxylase 85 40666 6.21 4 3 3 2 3 0.21 0.23
KINH_MOUSE Kinesin-1 heavy chain 85 109484 6.06 11 5 8 3 8 0.13 0.12
KANK2_MOUSE KN motif and ankyrin repeat domain-containing protein 2 85 90190 5.38 6 2 3 1 3 0.06 0.05
AGM1_MOUSE Phosphoacetylglucosamine mutase 84 59415 5.8 3 2 3 2 3 0.14 0.15
USP9X_MOUSE Probable ubiquitin carboxyl-terminal hydrolase FAF-X 84 290526 5.57 8 1 5 1 5 0.04 0.01
ADDA_MOUSE Alpha-adducin 84 80596 5.62 6 2 4 1 4 0.11 0.05
FA98B_MOUSE Protein FAM98B 84 45321 8.77 3 2 3 2 3 0.15 0.2
GALK2_MOUSE N-Acetylgalactosamine kinase 84 50470 6.47 10 4 6 3 6 0.38 0.39
UB2V1_MOUSE Ubiquitin-conjugating enzyme E2 variant 1 84 16344 7.74 11 3 6 2 6 0.58 0.65
PPGB_MOUSE Lysosomal protective protein 83 53809 5.56 9 3 8 3 8 0.27 0.26
EIF2A_MOUSE Eukaryotic translation initiation factor 2A 83 64363 9.04 11 6 5 4 5 0.14 0.3
CATH_MOUSE Pro-cathepsin H 83 37146 8.68 4 3 3 3 3 0.21 0.4
CD97_MOUSE CD97 antigen 83 90354 7.38 2 2 1 1 1 0.03 0.05
RDH11_MOUSE Retinol dehydrogenase 11 83 35125 9.1 10 6 5 3 5 0.24 0.43
QCR2_MOUSE Cytochrome b-c1 complex subunit 2, mitochondrial 82 48205 9.26 14 5 7 2 7 0.37 0.19
ITPA_MOUSE Inosine triphosphate pyrophosphatase 82 21883 5.6 5 2 2 1 2 0.15 0.21
TWF1_MOUSE Twinfilin-1 82 40054 6.21 7 4 4 3 4 0.19 0.37
SEPT9_MOUSE Septin-9 82 65534 9.01 16 5 9 3 9 0.23 0.21
PGFS_MOUSE Prostamide/prostaglandin F synthase 81 21656 6.31 2 2 1 1 1 0.15 0.21
ECI1_MOUSE Enoyl-CoA delta isomerase 1, mitochondrial 81 32230 9.12 3 3 2 2 2 0.13 0.29
RPE_MOUSE Ribulose-phosphate 3-epimerase 81 24928 5.2 3 3 2 2 2 0.24 0.39
RL13_MOUSE 60S ribosomal protein L13 80 24290 11.54 18 6 7 4 6 0.32 0.97
RWDD1_MOUSE RWD domain-containing protein 1 80 27768 4.18 4 2 2 1 2 0.23 0.16
CAN1_MOUSE Calpain-1 catalytic subunit 80 82054 5.62 3 2 3 2 3 0.09 0.11
ECM29_MOUSE Proteasome-associated protein ECM29 homolog 80 203573 6.68 10 4 7 4 7 0.08 0.09
ADA_MOUSE Adenosine deaminase 80 39966 5.48 3 2 3 2 3 0.27 0.23
PSMD7_MOUSE 26S proteasome non-ATPase regulatory subunit 7 80 36517 6.29 5 3 5 3 5 0.34 0.41
RAGP1_MOUSE Ran GTPase-activating protein 1 80 63491 4.59 8 5 5 4 5 0.15 0.3
ACON_MOUSE Aconitate hydratase, mitochondrial 79 85410 8.08 10 4 9 4 9 0.2 0.22
NEB2_MOUSE Neurabin-2 79 89466 4.86 5 2 4 2 4 0.13 0.1
IF2B_MOUSE Eukaryotic translation initiation factor 2 subunit 2 79 38068 5.61 6 4 4 3 4 0.18 0.39
NXP20_MOUSE Protein Noxp20 78 60975 4.49 6 3 4 2 4 0.11 0.15
ABCF1_MOUSE ATP-binding cassette sub-family F member 1 78 94887 6.15 9 3 6 3 6 0.11 0.14
HEM3_MOUSE Porphobilinogen deaminase 78 39320 6.41 4 2 3 1 3 0.17 0.11
CSN4_MOUSE COP9 signalosome complex subunit 4 78 46256 5.57 6 4 5 3 5 0.2 0.31
C1TM_MOUSE Monofunctional C1-tetrahydrofolate synthase, mitochondrial 78 105662 6.58 10 2 8 1 8 0.15 0.04
SPRE_MOUSE Sepiapterin reductase 78 27865 5.58 2 2 2 2 2 0.12 0.35
PLCD1_MOUSE 1-Phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 77 85819 5.82 3 2 1 1 1 0.02 0.05
IF2B2_MOUSE Insulin-like growth factor 2 mRNA-binding protein 2 77 65543 7.81 3 2 3 2 3 0.07 0.14
MCAT_MOUSE Mitochondrial carnitine/acylcarnitine carrier protein 77 33005 9.24 6 3 4 2 4 0.31 0.29
GSH0_MOUSE Glutamate–cysteine ligase regulatory subunit 76 30516 5.35 6 2 5 2 5 0.32 0.31
HA1B_MOUSE H-2 class I histocompatibility antigen, K-B alpha chain 76 41276 5.96 6 3 3 3 3 0.14 0.35
AR6P1_MOUSE ADP-ribosylation factor-like protein 6-interacting protein 1 76 23421 9.38 3 2 2 1 2 0.19 0.19
TM9S2_MOUSE Transmembrane 9 superfamily member 2 76 75280 7.21 6 3 5 2 5 0.14 0.12
SFXN1_MOUSE Sideroflexin-1 76 35626 9.35 4 1 4 1 4 0.26 0.12
RS21_MOUSE 40S ribosomal protein S21 76 9136 8.71 7 3 4 1 4 0.54 0.56
IL4RA_MOUSE Interleukin-4 receptor subunit alpha 76 87571 4.97 3 2 2 1 2 0.04 0.05
EIF1_MOUSE Eukaryotic translation initiation factor 1 75 12739 6.89 3 2 2 2 2 0.24 0.89
NUCB1_MOUSE Nucleobindin-1 75 53376 4.99 17 4 11 2 11 0.34 0.17
MMS19_MOUSE MMS19 nucleotide excision repair protein homolog 75 113017 5.81 4 2 3 2 3 0.07 0.08
GCP60_MOUSE Golgi resident protein GCP60 75 60144 5.07 12 5 5 2 5 0.2 0.15
FDFT_MOUSE Squalene synthase 75 48123 5.91 9 3 6 2 6 0.27 0.3
TPD52_MOUSE Tumor protein D52 75 24298 4.69 4 3 3 2 3 0.25 0.4
RBM3_MOUSE RNA-binding protein 3 75 16595 6.84 14 7 5 4 5 0.57 1.68
RBMS1_MOUSE RNA-binding motif, single-stranded-interacting protein 1 75 43963 8.79 3 2 3 2 3 0.21 0.21
NDUAA_MOUSE NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 75 40578 7.63 5 3 5 3 5 0.23 0.36
SRC8_MOUSE Src substrate cortactin 75 61212 5.24 10 2 8 2 8 0.15 0.15
HNRPC_MOUSE Heterogeneous nuclear ribonucleoproteins C1/C2 74 34364 4.92 2 1 2 1 2 0.09 0.13
CP20A_MOUSE Cytochrome P450 20A1 74 52116 6.48 5 3 4 2 4 0.19 0.17
LDLR_MOUSE Low-density lipoprotein receptor 74 94885 4.82 5 2 5 2 5 0.13 0.09
MARC2_MOUSE Mitochondrial amidoxime reducing component 2 73 38170 8.95 2 2 2 2 2 0.15 0.24
ERF3A_MOUSE Eukaryotic peptide chain release factor GTP-binding subunit ERF3A 73 68582 5.12 13 6 9 4 9 0.22 0.28
ALD2_MOUSE Aldose reductase-related protein 2 73 36098 5.97 4 2 4 2 4 0.2 0.26
ADPRH_MOUSE [Protein ADP-ribosylarginine] hydrolase 73 40042 5.46 3 2 3 2 3 0.22 0.23
ATP5I_MOUSE ATP synthase subunit e, mitochondrial 72 8230 9.34 9 4 4 2 4 0.62 1.66
GLU2B_MOUSE Glucosidase 2 subunit beta 72 58756 4.41 12 5 8 4 8 0.24 0.33
ACSL4_MOUSE Long-chain-fatty-acid–CoA ligase 4 72 79026 8.57 12 5 8 3 6 0.19 0.17
PUF60_MOUSE Poly(U)-binding-splicing factor PUF60 72 60211 5.2 6 2 5 1 5 0.24 0.07
PTPA_MOUSE Serine/threonine-protein phosphatase 2A activator 72 36687 5.95 5 2 4 1 4 0.29 0.12
PDXK_MOUSE Pyridoxal kinase 72 34993 5.88 4 2 4 2 4 0.19 0.27
AP1G1_MOUSE AP-1 complex subunit gamma-1 71 91292 6.36 6 4 5 3 5 0.16 0.15
ATG3_MOUSE Ubiquitin-like-conjugating enzyme ATG3 71 35773 4.63 4 2 3 1 3 0.28 0.26
KAP0_MOUSE cAMP-dependent protein kinase type I-alpha regulatory subunit 71 43158 5.27 9 2 8 2 8 0.28 0.21
IF4B_MOUSE Eukaryotic translation initiation factor 4B 71 68799 5.47 8 6 2 2 2 0.07 0.13
NPL4_MOUSE Nuclear protein localization protein 4 homolog 71 67974 6.01 3 1 3 1 3 0.11 0.06
CX6A1_MOUSE Cytochrome c oxidase subunit 6A1, mitochondrial 71 12344 9.97 3 2 2 1 2 0.45 0.39
CDC37_MOUSE Hsp90 co-chaperone Cdc37 71 44565 5.24 6 4 5 3 5 0.21 0.32
AN32A_MOUSE Acidic leucine-rich nuclear phosphoprotein 32 family member A 71 28520 3.99 4 2 4 2 4 0.22 0.34
PA24A_MOUSE Cytosolic phospholipase A2 71 85168 5.28 6 2 6 2 6 0.18 0.1
CO5A2_MOUSE Collagen alpha-2(V) chain 70 144929 6.28 17 7 9 5 9 0.14 0.16
ANXA7_MOUSE Annexin A7 70 49893 5.91 10 3 8 2 8 0.22 0.18
AIF1L_MOUSE Allograft inflammatory factor 1-like 70 17013 6.63 3 2 2 1 2 0.16 0.27
MECR_MOUSE Enoyl-[acyl-carrier-protein] reductase, mitochondrial 70 40317 9.17 3 3 1 1 1 0.09 0.11
MPI_MOUSE Mannose-6-phosphate isomerase 70 46545 5.62 2 1 2 1 2 0.1 0.09
SUCB2_MOUSE Succinate–CoA ligase [GDP-forming] subunit beta, mitochondrial 70 46811 6.58 4 1 4 1 4 0.14 0.09
MMAB_MOUSE Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial 69 26256 9.32 2 1 2 1 2 0.16 0.17
AGAL_MOUSE Alpha-galactosidase A 69 47611 5.44 4 2 4 2 4 0.14 0.19
SP16H_MOUSE FACT complex subunit SPT16 69 119749 5.5 4 1 4 1 4 0.07 0.04
NP1L4_MOUSE Nucleosome assembly protein 1-like 4 69 42653 4.56 9 3 7 3 5 0.32 0.34
UBQL1_MOUSE Ubiquilin-1 69 61937 4.86 10 4 6 3 6 0.24 0.22
RET1_MOUSE Retinol-binding protein 1 69 15836 5.1 4 2 4 2 4 0.44 0.68
ABHEB_MOUSE Protein ABHD14B 69 22437 5.82 2 1 2 1 2 0.1 0.2
HM13_MOUSE Minor histocompatibility antigen H13 69 41721 5.7 4 2 2 1 2 0.1 0.1
GALM_MOUSE Aldose 1-epimerase 68 37775 6.26 4 2 3 2 3 0.13 0.25
AP3B1_MOUSE AP-3 complex subunit beta-1 68 122664 5.49 13 3 9 3 9 0.11 0.11
LEG9_MOUSE Galectin-9 68 40010 9.41 9 3 6 3 6 0.24 0.37
SPART_MOUSE Spartin 68 72610 5.64 3 2 3 2 3 0.09 0.12
ERAP1_MOUSE Endoplasmic reticulum aminopeptidase 1 67 106531 5.82 7 3 5 3 5 0.09 0.12
PIEZ1_MOUSE Piezo-type mechanosensitive ion channel component 1 67 291813 7.41 2 1 2 1 2 0.01 0.01
AL1L2_MOUSE Mitochondrial 10-formyltetrahydrofolate dehydrogenase 67 101526 5.93 8 3 7 3 6 0.13 0.13
PDLI7_MOUSE PDZ and LIM domain protein 7 67 50087 8.82 5 1 5 1 5 0.23 0.09
ADA15_MOUSE Disintegrin and metalloproteinase domain-containing protein 15 67 92604 6.09 5 2 3 1 3 0.09 0.05
PGPI_MOUSE Pyroglutamyl-peptidase 1 66 22919 5.21 4 3 4 3 4 0.43 0.72
ANTR1_MOUSE Anthrax toxin receptor 1 66 62269 7.53 3 1 3 1 3 0.08 0.07
OSTF1_MOUSE Osteoclast-stimulating factor 1 66 23768 5.46 4 2 4 2 4 0.3 0.42
IL1RA_MOUSE Interleukin-1 receptor antagonist protein 66 20261 5.82 3 2 3 2 3 0.42 0.5
CC90B_MOUSE Coiled-coil domain-containing protein 90B, mitochondrial 66 29578 8.54 3 1 3 1 3 0.25 0.15
PON2_MOUSE Serum paraoxonase/arylesterase 2 66 39592 5.49 5 3 3 1 3 0.18 0.11
PGH1_MOUSE Prostaglandin G/H synthase 1 66 68998 6.36 7 5 6 5 6 0.12 0.35
NRADD_MOUSE Death domain-containing membrane protein NRADD 66 24711 4.89 2 2 1 1 1 0.14 0.18
PEA15_MOUSE Astrocytic phosphoprotein PEA-15 66 15045 4.94 9 3 4 3 4 0.45 1.26
B2MG_MOUSE Beta-2-microglobulin 66 13770 8.55 3 2 3 2 3 0.35 0.81
ACADM_MOUSE Medium-chain specific acyl-CoA dehydrogenase, mitochondrial 66 46452 8.6 4 2 4 2 4 0.18 0.2
SCRB2_MOUSE Lysosome membrane protein 2 65 54009 4.99 5 2 5 2 5 0.12 0.17
AATC_MOUSE Aspartate aminotransferase, cytoplasmic 65 46219 6.68 14 3 10 3 10 0.34 0.31
ERO1A_MOUSE ERO1-like protein alpha 65 54050 6.12 6 3 4 2 4 0.14 0.17
PUR8_MOUSE Adenylosuccinate lyase 65 54831 6.9 6 3 5 2 5 0.19 0.16
LSG1_MOUSE Large subunit GTPase 1 homolog 64 73111 6.08 5 2 4 1 4 0.1 0.06
NAGAB_MOUSE Alpha-N-acetylgalactosaminidase 64 47204 6.02 4 2 3 1 3 0.14 0.09
IDHG1_MOUSE Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial 64 42758 9.17 2 1 2 1 2 0.09 0.1
CTGF_MOUSE Connective tissue growth factor 64 37798 8.22 14 6 8 3 8 0.33 0.39
EFTS_MOUSE Elongation factor Ts, mitochondrial 64 35312 6.62 5 3 4 2 4 0.25 0.27
DBNL_MOUSE Drebrin-like protein 64 48670 4.9 5 1 4 1 4 0.13 0.09
TENA_MOUSE Tenascin 64 231659 4.77 11 3 8 2 8 0.09 0.04
SYTC_MOUSE Threonine–tRNA ligase, cytoplasmic 64 83303 7.03 6 4 5 4 5 0.12 0.22
TMM59_MOUSE Transmembrane protein 59 64 36290 4.8 2 1 2 1 2 0.12 0.12
ARK72_MOUSE Aflatoxin B1 aldehyde reductase member 2 63 40586 8.36 2 2 1 1 1 0.1 0.11
PR2C3_MOUSE Prolactin-2C3 63 25322 5.61 9 2 5 1 5 0.55 0.18
AL7A1_MOUSE Alpha-aminoadipic semialdehyde dehydrogenase 62 58824 7.16 5 4 5 4 5 0.15 0.33
STAT1_MOUSE Signal transducer and activator of transcription 1 49 87142 5.42 8 4 6 3 3 0.14 0.15
FMR1_MOUSE Synaptic functional regulator FMR1 62 68947 7.27 7 2 6 2 5 0.17 0.13
EGFR_MOUSE Epidermal growth factor receptor 59 134766 6.46 7 2 7 2 7 0.09 0.06
DCAKD_MOUSE Dephospho-CoA kinase domain-containing protein 61 26459 9.61 4 2 3 1 3 0.2 0.17
TIM13_MOUSE Mitochondrial import inner membrane translocase subunit Tim13 61 10451 8.42 6 2 2 1 2 0.26 0.47
ITAM_MOUSE Integrin alpha-M 61 127400 6.87 4 2 3 1 3 0.04 0.03
ARP10_MOUSE Actin-related protein 10 61 46178 7.54 2 2 2 2 2 0.05 0.2
TMED5_MOUSE Transmembrane emp24 domain-containing protein 5 61 26155 4.81 5 2 4 2 4 0.31 0.37
TRXR1_MOUSE Thioredoxin reductase 1, cytoplasmic 61 67042 7.42 9 6 7 5 7 0.22 0.37
NAGK_MOUSE N-acetyl-D-glucosamine kinase 60 37245 5.43 5 3 3 2 3 0.23 0.25
GAPR1_MOUSE Golgi-associated plant pathogenesis-related protein 1 60 17080 9.54 5 2 3 1 3 0.32 0.27
ODO2_MOUSE Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial 60 48963 9.11 8 2 7 2 7 0.2 0.19
STX7_MOUSE Syntaxin-7 60 29802 5.6 9 4 5 2 5 0.15 0.32
GID8_MOUSE Glucose-induced degradation protein 8 homolog 60 26762 4.92 4 2 3 1 3 0.3 0.17
PGBM_MOUSE Basement membrane-specific heparan sulfate proteoglycan core protein 60 398039 5.88 10 4 8 3 8 0.05 0.04
MDR1A_MOUSE Multidrug resistance protein 1A 60 140558 8.94 4 1 3 1 3 0.04 0.03
CASP1_MOUSE Caspase-1 59 45611 5.73 4 2 3 1 3 0.15 0.1
SYCC_MOUSE Cysteine–tRNA ligase, cytoplasmic 59 94800 6.32 13 3 8 3 8 0.15 0.14
PRRX1_MOUSE Paired mesoderm homeobox protein 1 59 27253 9.48 2 2 1 1 1 0.12 0.16
LY6A_MOUSE Lymphocyte antigen 6A-2/6E-1 59 14367 4.75 4 3 1 1 1 0.16 0.33
AMPD3_MOUSE AMP deaminase 3 59 88596 6.87 4 1 4 1 4 0.08 0.05
NDRG2_MOUSE Protein NDRG2 59 40763 5.23 2 1 2 1 2 0.12 0.11
S39AE_MOUSE Zinc transporter ZIP14 59 53927 5.11 1 1 1 1 1 0.06 0.08
PLPHP_MOUSE Pyridoxal phosphate homeostasis protein 59 30030 8.37 4 4 4 4 4 0.33 0.74
PSMD3_MOUSE 26S proteasome non-ATPase regulatory subunit 3 59 60680 8.48 7 2 6 2 6 0.18 0.15
TRADD_MOUSE Tumor necrosis factor receptor type 1-associated DEATH domain protein 59 34556 5.11 5 1 3 1 3 0.12 0.13
ANM5_MOUSE Protein arginine N-methyltransferase 5 59 72634 5.99 5 3 3 2 3 0.13 0.12
IPO9_MOUSE Importin-9 58 115978 4.71 6 2 4 2 4 0.09 0.07
VPS52_MOUSE Vacuolar protein sorting-associated protein 52 homolog 58 81993 5.65 7 2 3 1 3 0.07 0.05
LRRF1_MOUSE Leucine-rich repeat flightless-interacting protein 1 58 79201 4.75 2 1 2 1 2 0.08 0.05
E41L3_MOUSE Band 4.1-like protein 3 58 103274 5.2 5 2 4 2 4 0.05 0.08
EMIL1_MOUSE EMILIN-1 58 107518 5.21 3 1 3 1 3 0.06 0.04
EEA1_MOUSE Early endosome antigen 1 58 160817 5.59 6 2 5 2 5 0.06 0.05
MESD_MOUSE LRP chaperone MESD 58 25191 6.06 2 2 1 1 1 0.06 0.18
IMPCT_MOUSE Protein IMPACT 57 36253 4.97 3 2 3 2 3 0.15 0.26
GUAA_MOUSE GMP synthase [glutamine-hydrolyzing] 57 76675 6.29 4 2 3 1 3 0.11 0.06
GCSH_MOUSE Glycine cleavage system H protein, mitochondrial 57 18625 4.78 3 3 1 1 1 0.22 0.55
VA0D1_MOUSE V-type proton ATPase subunit d 1 57 40275 4.89 9 4 8 4 8 0.34 0.51
PUR2_MOUSE Trifunctional purine biosynthetic protein adenosine-3 57 107436 6.25 6 3 5 2 5 0.1 0.08
GLOD4_MOUSE Glyoxalase domain-containing protein 4 57 33296 5.28 2 2 2 2 2 0.17 0.28
WDR61_MOUSE WD repeat-containing protein 61 57 33752 5.1 3 2 3 2 3 0.18 0.28
CUL5_MOUSE Cullin-5 57 90916 7.86 10 2 6 1 6 0.17 0.05
NICA_MOUSE Nicastrin 57 78443 5.75 5 2 4 2 4 0.06 0.11
FKB14_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP14 57 24236 5.66 4 2 3 2 3 0.24 0.41
PLEK_MOUSE Pleckstrin 57 39876 8.53 3 2 3 2 3 0.19 0.23
LA_MOUSE Lupus La protein homolog 57 47727 9.77 5 2 5 2 5 0.13 0.19
TPBG_MOUSE Trophoblast glycoprotein 56 46422 6.36 5 2 5 2 5 0.18 0.2
ETHE1_MOUSE Persulfide dioxygenase ETHE1, mitochondrial 56 27721 6.78 2 1 2 1 2 0.23 0.16
UBR4_MOUSE E3 ubiquitin-protein ligase UBR4 56 571927 5.72 20 2 16 2 16 0.07 0.01
ACSA_MOUSE Acetyl-coenzyme A synthetase, cytoplasmic 56 78811 6.19 4 2 3 1 3 0.09 0.05
PSA_MOUSE Puromycin-sensitive aminopeptidase 56 103260 5.61 7 4 6 3 6 0.14 0.13
S10A4_MOUSE Protein S100-A4 56 11714 5.23 4 2 2 1 2 0.23 0.41
P3H3_MOUSE Prolyl 3-hydroxylase 3 55 81650 6.21 3 1 3 1 3 0.08 0.05
LMNA_MOUSE Prelamin-A/C 55 74193 6.54 10 1 5 1 5 0.11 0.06
VAC14_MOUSE Protein VAC14 homolog 54 87992 5.75 5 1 4 1 4 0.09 0.05
PYR1_MOUSE CAD protein 54 243084 6 13 5 11 4 11 0.11 0.07
ABRAL_MOUSE Costars family protein ABRACL 54 9025 5.52 4 1 3 1 3 0.57 0.56
CTND1_MOUSE Catenin delta-1 54 104860 6.41 8 2 8 2 8 0.12 0.08
FKB15_MOUSE FK506-binding protein 15 54 132878 4.98 4 2 3 1 3 0.06 0.03
ECE1_MOUSE Endothelin-converting enzyme 1 54 87017 5.64 5 5 5 5 5 0.17 0.27
AT5F1_MOUSE ATP synthase F(0) complex subunit B1, mitochondrial 54 28930 9.11 8 2 6 2 6 0.27 0.33
LDAH_MOUSE Lipid droplet-associated hydrolase 54 37349 8.5 3 1 2 1 2 0.18 0.12
TNIK_MOUSE Traf2 and NCK-interacting protein kinase 54 150274 6.82 9 2 7 1 7 0.07 0.03
EI2BA_MOUSE Translation initiation factor eIF-2B subunit alpha 54 33795 8.48 4 3 2 1 2 0.1 0.13
VAPA_MOUSE Vesicle-associated membrane protein-associated protein A 53 27837 8.59 9 2 6 2 6 0.36 0.35
DYLT3_MOUSE Dynein light chain Tctex-type 3 53 12949 4.98 1 1 1 1 1 0.29 0.37
ZZEF1_MOUSE Zinc finger ZZ-type and EF-hand domain-containing protein 1 53 328102 5.74 6 2 4 1 4 0.03 0.01
NDRG1_MOUSE Protein NDRG1 53 42981 5.69 5 2 4 2 4 0.21 0.21
PDLI5_MOUSE PDZ and LIM domain protein 5 53 63259 8.61 15 3 7 3 7 0.27 0.22
LIMA1_MOUSE LIM domain and actin-binding protein 1 53 84008 6.18 10 2 7 2 7 0.12 0.1
NPC2_MOUSE Epididymal secretory protein E1 53 16432 7.59 13 3 8 2 8 0.7 0.65
AN32B_MOUSE Acidic leucine-rich nuclear phosphoprotein 32 family member B 53 31060 3.89 2 1 2 1 2 0.11 0.14
ERP44_MOUSE Endoplasmic reticulum resident protein 44 53 46823 5.09 6 2 6 2 6 0.24 0.19
CBR2_MOUSE Carbonyl reductase [NADPH] 2 53 25942 9.1 2 2 2 2 2 0.23 0.38
TNR12_MOUSE Tumor necrosis factor receptor superfamily member 12A 53 13632 8.18 2 1 2 1 2 0.43 0.35
GGT5_MOUSE Glutathione hydrolase 5 proenzyme 53 61635 8.76 3 1 3 1 3 0.13 0.07
AL3A2_MOUSE Fatty aldehyde dehydrogenase 52 53936 8.59 2 2 2 2 2 0.09 0.17
MYDGF_MOUSE Myeloid-derived growth factor 52 17971 6.3 5 2 2 1 2 0.12 0.26
FKBP4_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP4 52 51540 5.54 4 2 3 1 3 0.13 0.08
AL1L1_MOUSE Cytosolic 10-formyltetrahydrofolate dehydrogenase 52 98647 5.64 9 2 7 2 6 0.17 0.09
TCP4_MOUSE Activated RNA polymerase II transcriptional coactivator p15 52 14418 9.6 5 2 3 1 3 0.28 0.33
GLO2_MOUSE Hydroxyacylglutathione hydrolase, mitochondrial 51 34062 7.66 4 2 2 1 2 0.14 0.28
PARK7_MOUSE Protein/nucleic acid deglycase DJ-1 51 20008 6.32 12 5 6 4 6 0.6 1.28
DHSO_MOUSE Sorbitol dehydrogenase 51 38225 6.56 1 1 1 1 1 0.03 0.11
TENS3_MOUSE Tensin-3 51 155491 6.19 6 1 4 1 4 0.07 0.03
RSU1_MOUSE Ras suppressor protein 1 51 31531 8.86 5 1 5 1 5 0.35 0.14
PAK2_MOUSE Serine/threonine-protein kinase PAK 2 49 57894 5.57 5 3 4 2 4 0.14 0.15
HSBP1_MOUSE Heat shock factor-binding protein 1 51 8605 4.11 3 2 2 1 2 0.58 0.59
TMX3_MOUSE Protein disulfide-isomerase TMX3 51 51815 5.02 4 2 4 2 4 0.17 0.17
CREG1_MOUSE Protein CREG1 51 24436 5.96 4 3 3 3 3 0.23 0.66
MRP1_MOUSE Multidrug resistance-associated protein 1 50 171075 7.03 2 1 2 1 2 0.04 0.02
NU4M_MOUSE NADH-ubiquinone oxidoreductase chain 4 50 51847 9.42 4 3 3 2 3 0.11 0.17
TIMP2_MOUSE Metalloproteinase inhibitor 2 50 24312 7.45 6 2 6 2 6 0.5 0.4
NUP93_MOUSE Nuclear pore complex protein Nup93 50 93222 5.5 5 2 5 2 5 0.09 0.09
TGBR3_MOUSE Transforming growth factor beta receptor type 3 50 93769 5.65 7 4 4 2 4 0.1 0.14
RM46_MOUSE 39S ribosomal protein L46, mitochondrial 50 32112 6.93 4 1 3 1 3 0.14 0.14
SRXN1_MOUSE Sulfiredoxin-1 50 14140 7.82 4 1 2 1 2 0.26 0.34
SYQ_MOUSE Glutamine–tRNA ligase 50 87621 6.93 9 2 6 1 6 0.16 0.05
SORCN_MOUSE Sorcin 50 21613 5.32 10 2 4 1 4 0.26 0.21
NDUA2_MOUSE NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 50 10909 10.02 3 2 1 1 1 0.14 0.45
NASP_MOUSE Nuclear autoantigenic sperm protein 50 83903 4.35 4 2 4 2 4 0.1 0.1
A16A1_MOUSE Aldehyde dehydrogenase family 16 member A1 49 84703 5.9 1 1 1 1 1 0.04 0.05
NQO1_MOUSE NAD(P)H dehydrogenase [quinone] 1 49 30940 8.74 12 4 6 2 6 0.36 0.31
NRBP_MOUSE Nuclear receptor-binding protein 49 59828 5.02 1 1 1 1 1 0.06 0.07
NIF3L_MOUSE NIF3-like protein 1 49 41719 6.28 5 2 3 1 3 0.12 0.1
NDUS4_MOUSE NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 49 19772 10 3 1 3 1 2 0.26 0.23
CERS2_MOUSE Ceramide synthase 2 49 44995 8.85 1 1 1 1 1 0.05 0.1
GT251_MOUSE Procollagen galactosyltransferase 1 49 71015 6.83 11 4 9 4 9 0.28 0.27
S23IP_MOUSE SEC23-interacting protein 49 110711 5.63 4 1 3 1 3 0.07 0.04
DDRGK_MOUSE DDRGK domain-containing protein 1 49 35956 5.32 3 1 2 1 2 0.13 0.12
LMAN1_MOUSE Protein ERGIC-53 49 57753 5.92 11 5 7 4 7 0.25 0.34
AHSA1_MOUSE Activator of 90 kDa heat shock protein ATPase homolog 1 49 38093 5.41 5 2 5 2 5 0.27 0.24
HMGCL_MOUSE Hydroxymethylglutaryl-CoA lyase, mitochondrial 48 34217 8.7 3 2 3 2 3 0.2 0.27
PURA2_MOUSE Adenylosuccinate synthetase isozyme 2 48 49990 5.98 6 2 5 2 5 0.16 0.18
SYK_MOUSE Lysine–tRNA ligase 48 67796 5.65 6 1 4 1 4 0.11 0.06
CGAT1_MOUSE Chondroitin sulfate N-acetylgalactosaminyltransferase 1 48 60878 9.03 1 1 1 1 1 0.03 0.07
NSDHL_MOUSE Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating 48 40660 7.71 6 4 4 3 4 0.19 0.36
KTN1_MOUSE Kinectin 48 152498 5.67 11 1 11 1 11 0.12 0.03
BID_MOUSE BH3-interacting domain death agonist 48 21938 4.71 2 2 2 2 2 0.15 0.46
DEGS1_MOUSE Sphingolipid delta(4)-desaturase DES1 45 38216 7.33 2 2 2 2 2 0.1 0.24
EP15R_MOUSE Epidermal growth factor receptor substrate 15-like 1 47 99248 4.86 8 2 6 1 6 0.17 0.04
ARL2_MOUSE ADP-ribosylation factor-like protein 2 47 20851 5.67 1 1 1 1 1 0.14 0.22
NPC1_MOUSE Niemann-Pick C1 protein 47 142791 5.44 5 2 4 2 4 0.06 0.06
WASC2_MOUSE WASH complex subunit 2 47 145224 4.63 4 2 4 2 4 0.05 0.06
NPL_MOUSE N-Acetylneuraminate lyase 47 35108 7.74 3 2 1 1 1 0.09 0.27
CD63_MOUSE CD63 antigen 47 25749 6.69 4 2 4 2 4 0.23 0.38
GLRX3_MOUSE Glutaredoxin-3 47 37754 5.42 12 3 11 3 11 0.6 0.39
DNJB4_MOUSE DnaJ homolog subfamily B member 4 47 37758 8.7 2 1 2 1 2 0.08 0.12
DC1L2_MOUSE Cytoplasmic dynein 1 light intermediate chain 2 46 54185 5.89 7 3 7 3 6 0.25 0.26
ULA1_MOUSE NEDD8-activating enzyme E1 regulatory subunit 46 60236 5.34 6 3 4 2 4 0.16 0.23
SETD3_MOUSE Histone-lysine N-methyltransferase setd3 44 67134 5.47 2 2 2 2 2 0.08 0.13
LXN_MOUSE Latexin 46 25476 5.48 2 1 2 1 2 0.14 0.18
MPEG1_MOUSE Macrophage-expressed gene 1 protein 46 78340 5.64 4 2 3 1 3 0.1 0.05
YKT6_MOUSE Synaptobrevin homolog YKT6 46 22300 5.97 4 1 4 1 4 0.35 0.2
GSHR_MOUSE Glutathione reductase, mitochondrial 46 53629 8.19 8 2 6 1 6 0.19 0.08
CP062_MOUSE UPF0505 protein C16orf62 homolog 46 109007 6.97 3 1 3 1 3 0.06 0.04
SCMC1_MOUSE Calcium-binding mitochondrial carrier protein SCaMC-1 46 52868 7.02 7 2 6 2 6 0.23 0.17
CO4A2_MOUSE Collagen alpha-2(IV) chain 46 167220 8.75 4 1 4 1 4 0.04 0.03
RDH13_MOUSE Retinol dehydrogenase 13 46 36441 9.02 2 1 2 1 2 0.08 0.12
DPP2_MOUSE Dipeptidyl peptidase 2 46 56218 5.17 1 1 1 1 1 0.03 0.08
ATX10_MOUSE Ataxin-10 46 53673 5.12 5 2 4 2 4 0.12 0.17
APMAP_MOUSE Adipocyte plasma membrane-associated protein 45 46405 5.97 2 2 1 1 1 0.07 0.09
EFHD2_MOUSE EF-hand domain-containing protein D2 45 26775 5.01 8 1 3 1 3 0.12 0.17
PEDF_MOUSE Pigment epithelium-derived factor 45 46205 6.48 3 1 2 1 2 0.1 0.09
SODC_MOUSE Superoxide dismutase [Cu-Zn] 45 15933 6.02 9 3 5 2 5 0.39 0.67
S38A2_MOUSE Sodium-coupled neutral amino acid transporter 2 45 55467 8.05 4 2 4 2 4 0.16 0.16
NUP50_MOUSE Nuclear pore complex protein Nup50 45 49455 5.94 3 1 3 1 3 0.16 0.09
CD44_MOUSE CD44 antigen 45 85565 4.82 6 1 5 1 5 0.11 0.05
NDUS8_MOUSE NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 45 24023 5.89 1 1 1 1 1 0.04 0.19
STX2_MOUSE Syntaxin-2 45 33157 5.98 2 1 1 1 1 0.11 0.13
TMED3_MOUSE Transmembrane emp24 domain-containing protein 3 45 25449 5.62 3 2 2 2 2 0.16 0.38
VMP1_MOUSE Vacuole membrane protein 1 45 45931 6.47 1 1 1 1 1 0.07 0.09
PRAF1_MOUSE Prenylated Rab acceptor protein 1 45 20606 7.74 1 1 1 1 1 0.08 0.22
ARMC6_MOUSE Armadillo repeat-containing protein 6 44 50651 5.65 2 1 2 1 2 0.12 0.09
GRHPR_MOUSE Glyoxylate reductase/hydroxypyruvate reductase 44 35306 7.57 3 3 2 2 2 0.16 0.27
CRTAP_MOUSE Cartilage-associated protein 44 46140 5.46 3 3 3 3 3 0.14 0.31
TM14C_MOUSE Transmembrane protein 14C 44 11634 9.7 2 2 2 2 2 0.51 1.01
COX5B_MOUSE Cytochrome c oxidase subunit 5B, mitochondrial 44 13804 8.69 10 4 3 2 3 0.34 0.81
NNRE_MOUSE NAD(P)H-hydrate epimerase 44 30953 7.59 2 2 2 2 2 0.1 0.31
TPR_MOUSE Nucleoprotein TPR 44 273824 4.98 10 1 10 1 10 0.06 0.02
SYFA_MOUSE Phenylalanine–tRNA ligase alpha subunit 44 57563 8.27 3 1 2 1 2 0.05 0.08
E41L2_MOUSE Band 4.1-like protein 2 43 109873 5.31 7 1 7 1 7 0.09 0.04
CBR3_MOUSE Carbonyl reductase [NADPH] 3 43 30934 6.15 4 2 3 2 3 0.19 0.31
NDUB7_MOUSE NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 43 16320 8.35 5 2 2 2 2 0.26 0.65
LRN4L_MOUSE LRRN4 C-terminal-like protein 43 25914 5.15 2 1 2 1 2 0.11 0.17
CSTFT_MOUSE Cleavage stimulation factor subunit 2 tau variant 43 65820 6.78 4 1 3 1 3 0.13 0.07
RFA2_MOUSE Replication protein A 32 kDa subunit 43 29700 5.76 1 1 1 1 1 0.09 0.15
NPS3B_MOUSE Protein NipSnap homolog 3B 43 28290 9.51 2 2 1 1 1 0.1 0.16
HDAC7_MOUSE Histone deacetylase 7 43 101224 7.11 2 1 2 1 2 0.07 0.04
PEX19_MOUSE Peroxisomal biogenesis factor 19 43 32713 4.26 4 1 4 1 4 0.34 0.14
GALK1_MOUSE Galactokinase 43 42268 5.17 7 2 5 2 5 0.21 0.22
DCTN1_MOUSE Dynactin subunit 1 43 141588 5.66 7 2 6 2 6 0.08 0.06
OAS1A_MOUSE 2 -5 -Oligoadenylate synthase 1A 43 42402 8.3 2 1 2 1 2 0.08 0.1
FKBP3_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP3 43 25132 9.29 3 2 3 2 3 0.21 0.39
GIPC1_MOUSE PDZ domain-containing protein GIPC1 43 36107 5.65 3 2 3 2 3 0.17 0.26
EMC3_MOUSE ER membrane protein complex subunit 3 43 29960 6.33 3 1 3 1 3 0.17 0.15
MMSA_MOUSE Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial 43 57878 8.29 2 1 2 1 2 0.06 0.07
PLXB2_MOUSE Plexin-B2 43 206099 5.58 12 1 9 1 9 0.09 0.02
FADS3_MOUSE Fatty acid desaturase 3 42 51436 7 1 1 1 1 1 0.07 0.08
FUND2_MOUSE FUN14 domain-containing protein 2 42 16554 9.71 1 1 1 1 1 0.07 0.28
GPX7_MOUSE Glutathione peroxidase 7 42 21048 8.42 3 1 3 1 3 0.28 0.22
MTX2_MOUSE Metaxin-2 42 29739 5.44 2 1 2 1 2 0.16 0.15
HTR5A_MOUSE HEAT repeat-containing protein 5A 42 219754 6.31 4 1 4 1 4 0.05 0.02
ALG11_MOUSE GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase 42 55234 8.58 3 1 2 1 2 0.09 0.08
DHSD_MOUSE Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial 42 17003 9.3 4 2 2 1 2 0.23 0.27
UBP19_MOUSE Ubiquitin carboxyl-terminal hydrolase 19 42 150454 5.99 3 1 3 1 3 0.04 0.03
OSMR_MOUSE Oncostatin-M-specific receptor subunit beta 42 110160 6.16 3 1 1 1 1 0.04 0.04
PGP_MOUSE Glycerol-3-phosphate phosphatase 42 34519 5.21 3 1 2 1 2 0.2 0.13
DDR2_MOUSE Discoidin domain-containing receptor 2 38 96420 5.31 3 2 2 2 2 0.05 0.09
F162A_MOUSE Protein FAM162A 42 17713 9.9 3 1 3 1 3 0.25 0.26
ACOT9_MOUSE Acyl-coenzyme A thioesterase 9, mitochondrial 41 50528 8.74 8 3 5 2 5 0.16 0.18
UCHL1_MOUSE Ubiquitin carboxyl-terminal hydrolase isozyme L1 41 24822 5.14 4 2 3 1 3 0.22 0.18
TPP2_MOUSE Tripeptidyl-peptidase 2 41 139790 6.13 9 3 7 3 7 0.11 0.09
HEXB_MOUSE Beta-hexosaminidase subunit beta 41 61077 8.29 5 1 3 1 3 0.14 0.07
CDIPT_MOUSE CDP-diacylglycerol–inositol 3-phosphatidyltransferase 41 23583 8.56 2 1 2 1 2 0.21 0.19
GAS6_MOUSE Growth arrest-specific protein 6 41 74561 5.34 5 2 4 1 4 0.09 0.06
PIN1_MOUSE Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 41 18359 8.93 2 1 2 1 2 0.19 0.25
APOE_MOUSE Apolipoprotein E 41 35844 5.56 1 1 1 1 1 0.06 0.12
SGMR1_MOUSE Sigma nonopioid intracellular receptor 1 41 25234 5.56 1 1 1 1 1 0.15 0.18
RTRAF_MOUSE RNA transcription, translation and transport factor protein 41 28135 6.4 4 1 3 1 3 0.21 0.16
TF_MOUSE Tissue factor 41 32914 9.4 5 2 5 2 5 0.26 0.29
ERGI3_MOUSE Endoplasmic reticulum-Golgi intermediate compartment protein 3 40 43181 6.02 3 2 2 1 2 0.17 0.21
LONM_MOUSE Lon protease homolog, mitochondrial 40 105776 6.15 6 1 5 1 5 0.14 0.04
TXD17_MOUSE Thioredoxin domain-containing protein 17 40 14006 4.72 3 1 2 1 2 0.19 0.34
DJC10_MOUSE DnaJ homolog subfamily C member 10 40 90525 6.53 7 2 4 2 4 0.09 0.1
PML_MOUSE Protein PML 40 98180 5.42 4 1 4 1 4 0.09 0.04
NAGA_MOUSE N-Acetylglucosamine-6-phosphate deacetylase 40 43473 5.78 1 1 1 1 1 0.07 0.1
HGH1_MOUSE Protein HGH1 homolog 40 42889 4.66 1 1 1 1 1 0.06 0.1
GLRX5_MOUSE Glutaredoxin-related protein 5, mitochondrial 40 16282 6.1 2 1 2 1 2 0.14 0.29
IPO11_MOUSE Importin-11 40 112344 5.14 3 1 3 1 3 0.07 0.04
T176A_MOUSE Transmembrane protein 176A 40 26579 7.62 3 1 2 1 2 0.16 0.17
S10AD_MOUSE Protein S100-A13 40 11151 5.89 2 1 2 1 2 0.23 0.44
PEX14_MOUSE Peroxisomal membrane protein PEX14 40 41183 5.03 2 1 2 1 2 0.15 0.11
DHRS1_MOUSE Dehydrogenase/reductase SDR family member 1 40 33983 8.66 6 2 5 2 5 0.28 0.28
MVD1_MOUSE Diphosphomevalonate decarboxylase 40 44044 5.89 3 2 3 2 3 0.19 0.21
VCAM1_MOUSE Vascular cell adhesion protein 1 40 81265 5.21 5 2 3 1 3 0.09 0.05
PRDX3_MOUSE Thioredoxin-dependent peroxide reductase, mitochondrial 40 28109 7.15 7 2 6 2 6 0.39 0.34
PP14B_MOUSE Protein phosphatase 1 regulatory subunit 14B 40 15947 4.74 2 1 2 1 2 0.33 0.29
BPNT1_MOUSE 3 (2 ),5 -Bisphosphate nucleotidase 1 39 33175 5.54 3 1 3 1 3 0.15 0.13
FAF2_MOUSE FAS-associated factor 2 39 52438 5.35 6 1 4 1 4 0.23 0.08
TI8AB_MOUSE Putative mitochondrial import inner membrane translocase subunit Tim8 A-B 39 11276 6.11 4 1 3 1 3 0.39 0.43
GBP2_MOUSE Guanylate-binding protein 2 39 66697 5.56 3 1 3 1 3 0.14 0.06
ABCD3_MOUSE ATP-binding cassette sub-family D member 3 39 75426 9.32 7 2 7 2 7 0.18 0.12
DPP9_MOUSE Dipeptidyl peptidase 9 39 97939 6.18 3 2 2 1 2 0.05 0.04
MSMO1_MOUSE Methylsterol monooxygenase 1 39 34750 7.29 2 1 1 1 1 0.1 0.13
TRNT1_MOUSE CCA tRNA nucleotidyltransferase 1, mitochondrial 39 49864 8.65 3 2 2 1 2 0.07 0.09
RIPK3_MOUSE Receptor-interacting serine/threonine-protein kinase 3 39 53289 7.22 8 3 6 3 6 0.17 0.26
ERGI1_MOUSE Endoplasmic reticulum-Golgi intermediate compartment protein 1 39 32541 6.59 4 2 3 1 3 0.14 0.14
P2RX4_MOUSE P2X purinoceptor 4 38 43410 8.29 2 2 1 1 1 0.07 0.1
FCGRN_MOUSE IgG receptor FcRn large subunit p51 38 40067 5.2 2 2 2 2 2 0.1 0.23
NCF2_MOUSE Neutrophil cytosol factor 2 38 59448 6.18 2 1 2 1 2 0.09 0.07
TOIP2_MOUSE Torsin-1A-interacting protein 2 38 54463 4.75 2 1 2 1 2 0.12 0.08
DHB11_MOUSE Estradiol 17-beta-dehydrogenase 11 38 32860 8.85 2 2 1 1 1 0.06 0.13
SGTA_MOUSE Small glutamine-rich tetratricopeptide repeat-containing protein alpha 38 34301 4.99 4 2 3 2 3 0.12 0.27
HEM2_MOUSE Delta-aminolevulinic acid dehydratase 38 36000 6.32 1 1 1 1 1 0.06 0.12
CX7A2_MOUSE Cytochrome c oxidase subunit 7A2, mitochondrial 38 9285 10.28 3 1 3 1 3 0.53 0.54
PSB8_MOUSE Proteasome subunit beta type-8 38 30241 6.22 4 1 4 1 4 0.19 0.15
DECR_MOUSE 2,4-Dienoyl-CoA reductase, mitochondrial 36 36191 9.1 4 2 4 2 4 0.2 0.26
XPP1_MOUSE Xaa-Pro aminopeptidase 1 37 69547 5.33 3 2 3 2 3 0.09 0.13
SYYC_MOUSE Tyrosine–tRNA ligase, cytoplasmic 37 59068 6.57 6 1 6 1 6 0.16 0.07
FLOT1_MOUSE Flotillin-1 37 47484 6.71 12 2 4 1 4 0.13 0.09
BAP31_MOUSE B cell receptor-associated protein 31 37 27939 8.73 5 1 3 1 3 0.16 0.16
NECP2_MOUSE Adaptin ear-binding coat-associated protein 2 37 28580 7.71 9 4 4 2 4 0.28 0.34
GINM1_MOUSE Glycoprotein integral membrane protein 1 37 36056 5.45 1 1 1 1 1 0.05 0.12
ATG7_MOUSE Ubiquitin-like modifier-activating enzyme ATG7 37 77470 5.97 5 1 5 1 5 0.12 0.06
MA2B2_MOUSE Epididymis-specific alpha-mannosidase 37 115537 6.9 1 1 1 1 1 0.02 0.04
TB182_MOUSE 182 kDa tankyrase-1-binding protein 37 181714 4.8 5 1 4 1 4 0.04 0.02
PICAL_MOUSE Phosphatidylinositol-binding clathrin assembly protein 37 71498 7.71 4 1 4 1 4 0.1 0.06
PELP1_MOUSE Proline-, glutamic acid-, and leucine-rich protein 1 37 117995 4.31 2 1 2 1 2 0.05 0.04
ARHG7_MOUSE Rho guanine nucleotide exchange factor 7 37 96995 6.35 5 1 3 1 3 0.09 0.04
RT11_MOUSE 28S ribosomal protein S11, mitochondrial 37 20196 10.77 2 1 2 1 2 0.18 0.23
ODP2_MOUSE Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial 37 67899 8.81 7 1 5 1 5 0.13 0.06
NT5C_MOUSE 5 (3 )-Deoxyribonucleotidase, cytosolic type 37 23062 5.31 2 1 2 1 2 0.22 0.2
INF2_MOUSE Inverted formin-2 37 138474 5.09 5 1 4 1 4 0.07 0.03
WIPI1_MOUSE WD repeat domain phosphoinositide-interacting protein 1 37 48727 6.03 2 1 2 1 2 0.09 0.09
GPDM_MOUSE Glycerol-3-phosphate dehydrogenase, mitochondrial 37 80902 6.17 7 2 5 2 5 0.11 0.11
ATP8_MOUSE ATP synthase protein 8 36 7761 9.88 2 1 1 1 1 0.15 0.67
BST2_MOUSE Bone marrow stromal antigen 2 36 19140 6.82 2 2 1 1 1 0.05 0.24
DERL2_MOUSE Derlin-2 36 27621 6.73 1 1 1 1 1 0.13 0.16
IF4G2_MOUSE Eukaryotic translation initiation factor 4 gamma 2 36 102041 6.7 6 1 6 1 6 0.1 0.04
FKBP7_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP7 36 24897 5.69 3 2 3 2 3 0.17 0.39
PLP2_MOUSE Proteolipid protein 2 36 16597 6.69 4 3 1 1 1 0.08 0.28
RL29_MOUSE 60S ribosomal protein L29 36 17576 11.84 5 1 5 1 5 0.34 0.26
WASH1_MOUSE WASH complex subunit 1 36 51627 5.33 2 1 2 1 2 0.12 0.08
SIAS_MOUSE Sialic acid synthase 36 39998 6.61 6 1 5 1 5 0.23 0.11
RT28_MOUSE 28S ribosomal protein S28, mitochondrial 36 20508 9.1 1 1 1 1 1 0.13 0.22
FACE1_MOUSE CAAX prenyl protease 1 homolog 36 54699 6.49 2 1 2 1 2 0.09 0.08
MEP50_MOUSE Methylosome protein 50 36 36919 5.09 1 1 1 1 1 0.09 0.12
SCFD2_MOUSE Sec1 family domain-containing protein 2; OS = Mus musculus, GN = Scfd2, PE = 1, SV = 1 36 74703 6.35 4 1 4 1 4 0.11 0.06
PTN9_MOUSE Tyrosine-protein phosphatase nonreceptor type 9; OS = Mus musculus, GN = Ptpn9, PE = 1, SV = 2 36 67927 8.34 3 1 2 1 2 0.07 0.06
MXRA8_MOUSE Matrix remodeling-associated protein 8; OS = Mus musculus, GN = Mxra8, PE = 1, SV = 1 36 49719 6.66 2 1 2 1 2 0.05 0.09
COASY_MOUSE Bifunctional coenzyme A synthase; OS = Mus musculus, GN = Coasy, PE = 1, SV = 2 36 61985 6.61 4 2 3 2 3 0.13 0.14
PFD1_MOUSE Prefoldin subunit 1; OS = Mus musculus, GN = Pfdn1, PE = 1, SV = 1 35 14246 7.93 5 2 2 1 2 0.17 0.33
COX7C_MOUSE Cytochrome c oxidase subunit 7C, mitochondrial; OS = Mus musculus, GN = Cox7c, PE = 1, SV = 1 35 7328 11 2 1 1 1 1 0.33 0.72
ZCCHV_MOUSE Zinc finger CCCH-type antiviral protein 1; OS = Mus musculus, GN = Zc3hav1, PE = 1, SV = 1 35 106619 8.59 4 1 4 1 4 0.11 0.04
ASC_MOUSE Apoptosis-associated speck-like protein containing a CARD; OS = Mus musculus, GN = Pycard, PE = 1, SV = 1 35 21445 5.26 2 1 2 1 2 0.2 0.21
KCY_MOUSE UMP-CMP kinase; OS = Mus musculus, GN = Cmpk1, PE = 1, SV = 1 35 22151 5.68 4 2 4 2 4 0.3 0.45
HINT1_MOUSE Histidine triad nucleotide-binding protein 1; OS = Mus musculus, GN = Hint1, PE = 1, SV = 3 35 13768 6.36 6 1 1 1 1 0.11 0.35
ARSA_MOUSE Arylsulfatase A; OS = Mus musculus, GN = Arsa, PE = 1, SV = 2 35 53714 5.5 2 1 2 1 2 0.15 0.08
MIC13_MOUSE MICOS complex subunit MIC13; OS = Mus musculus, GN = Mic13, PE = 1, SV = 1 35 13365 8.68 2 1 2 1 2 0.27 0.36
NUCB2_MOUSE Nucleobindin-2 OS = Mus musculus, GN = Nucb2, PE = 1, SV = 2 35 50273 5.05 8 2 6 1 6 0.2 0.09
CHMP5_MOUSE Charged multivesicular body protein 5; OS = Mus musculus, GN = Chmp5, PE = 1, SV = 1 35 24560 4.65 5 1 2 1 2 0.2 0.18
HOME3_MOUSE Homer protein homolog 3 OS = Mus musculus GN = Homer3 PE = 1 SV = 2 35 39670 5.33 1 1 1 1 1 0.04 0.11
NHLC3_MOUSE NHL repeat-containing protein 3; OS = Mus musculus, GN = Nhlrc3, PE = 1, SV = 1 34 38171 5.81 1 1 1 1 1 0.03 0.11
CTBP2_MOUSE C-terminal-binding protein 2; OS = Mus musculus, GN = Ctbp2, PE = 1, SV = 2 34 48926 6.47 1 1 1 1 1 0.07 0.09
NU160_MOUSE Nuclear pore complex protein Nup160; OS = Mus musculus, GN = Nup160, PE = 1, SV = 2 34 158130 5.32 5 1 4 1 4 0.04 0.03
RAB34_MOUSE Ras-related protein Rab-34; OS = Mus musculus, GN = Rab34, PE = 1, SV = 2 34 29082 8.55 6 2 4 2 4 0.22 0.33
COMD8_MOUSE COMM domain-containing protein 8; OS = Mus musculus, GN = Commd8, PE = 1, SV = 1 34 20839 5.38 2 1 2 1 2 0.3 0.22
HECD1_MOUSE E3 ubiquitin-protein ligase HECTD1; OS = Mus musculus, GN = Hectd1, PE = 1, SV = 2 34 289905 5.26 12 1 11 1 11 0.08 0.01
LYRIC_MOUSE Protein LYRIC; OS = Mus musculus, GN = Mtdh, PE = 1, SV = 1 34 63808 9.34 5 3 4 3 4 0.2 0.22
S35F6_MOUSE Solute carrier family 35 member F6; OS = Mus musculus, GN = Slc35f6, PE = 1, SV = 1 34 40952 6.65 2 1 2 1 2 0.17 0.11
SBDS_MOUSE Ribosome maturation protein SBDS; OS = Mus musculus, GN = Sbds, PE = 1, SV = 4 34 28762 8.92 2 1 1 1 1 0.09 0.15
RHG01_MOUSE Rho GTPase-activating protein 1; OS = Mus musculus, GN = Arhgap1, PE = 1, SV = 1 34 50379 5.97 5 3 3 3 3 0.12 0.28
FACR1_MOUSE Fatty acyl-CoA reductase 1; OS = Mus musculus, GN = Far1, PE = 1, SV = 1 34 59397 9.26 4 1 2 1 2 0.09 0.07
MPRD_MOUSE Cation-dependent mannose-6-phosphate receptor; OS = Mus musculus, GN = M6pr, PE = 1, SV = 1 33 31152 5.24 3 2 2 1 2 0.13 0.14
PNKP_MOUSE Bifunctional polynucleotide phosphatase/kinase; OS = Mus musculus, GN = Pnkp, PE = 1, SV = 2 33 57188 8.03 9 1 5 1 5 0.15 0.08
DCPS_MOUSE m7GpppX diphosphatase; OS = Mus musculus, GN = Dcps, PE = 1, SV = 1 33 38964 6.02 2 1 2 1 2 0.1 0.11
DHX29_MOUSE ATP-dependent RNA helicase DHX29; OS = Mus musculus, GN = Dhx29, PE = 1, SV = 1 33 153879 8.13 11 2 9 1 9 0.1 0.03
CN37_MOUSE 2 ,3 -Cyclic-nucleotide 3 -phosphodiesterase; OS = Mus musculus, GN = Cnp, PE = 1, SV = 3 33 47094 9.08 1 1 1 1 1 0.07 0.09
TBCB_MOUSE Tubulin-folding cofactor B; OS = Mus musculus, GN = Tbcb, PE = 1, SV = 2 33 27368 5.14 3 1 3 1 3 0.23 0.16
SFPQ_MOUSE Splicing factor, proline- and glutamine-rich; OS = Mus musculus, GN = Sfpq, PE = 1, SV = 1 33 75394 9.45 3 1 2 1 2 0.07 0.06
GLYG_MOUSE Glycogenin-1; OS = Mus musculus, GN = Gyg1, PE = 1, SV = 3 33 37378 5.06 2 1 2 1 2 0.12 0.12
TSPO_MOUSE Translocator protein; OS = Mus musculus, GN = Tspo, PE = 1, SV = 1 33 18829 9.52 2 1 2 1 2 0.3 0.24
CND1_MOUSE Condensin complex subunit 1; OS = Mus musculus, GN = Ncapd2, PE = 1, SV = 2 33 155567 5.98 4 1 3 1 3 0.04 0.03
JIP4_MOUSE C-Jun-amino-terminal kinase-interacting protein 4; OS = Mus musculus, GN = Spag9, PE = 1, SV = 2 33 146129 5.05 6 1 6 1 6 0.08 0.03
NDUB9_MOUSE NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; OS = Mus musculus, GN = Ndufb9, PE = 1, SV = 3 33 21970 7.67 2 2 1 1 1 0.16 0.21
RBGP1_MOUSE Rab GTPase-activating protein 1; OS = Mus musculus, GN = Rabgap1, PE = 1, SV = 1 32 120722 5.14 5 1 3 1 3 0.03 0.04
F13A_MOUSE Coagulation factor XIII A chain; OS = Mus musculus, GN = F13a1, PE = 1, SV = 3 32 83155 5.63 4 3 2 2 2 0.06 0.11
DOCK7_MOUSE Dedicator of cytokinesis protein 7; OS = Mus musculus, GN = Dock7, PE = 1, SV = 3 32 241286 6.25 6 1 6 1 6 0.04 0.02
IC1_MOUSE Plasma protease C1 inhibitor; OS = Mus musculus, GN = Serping1, PE = 1, SV = 3 32 55549 5.87 2 1 2 1 2 0.13 0.08
SRP54_MOUSE Signal recognition particle 54 kDa protein; OS = Mus musculus, GN = Srp54, PE = 1, SV = 2 32 55684 8.87 15 3 10 3 10 0.38 0.25
YIF1B_MOUSE Protein YIF1B; OS = Mus musculus, GN = Yif1b, PE = 1, SV = 2 32 33961 9.19 5 1 2 1 2 0.14 0.13
TPC13_MOUSE Trafficking protein particle complex subunit 13; OS = Mus musculus, GN = Trappc13, PE = 2, SV = 1 32 46446 5.33 3 1 2 1 2 0.12 0.09
MCL1_MOUSE Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; OS = Mus musculus, GN = Mcl1, PE = 1, SV = 3 32 35195 5.88 1 1 1 1 1 0.06 0.13
FPRP_MOUSE Prostaglandin F2 receptor negative regulator; OS = Mus musculus, GN = Ptgfrn, PE = 1, SV = 2 32 98660 6.16 4 1 2 1 2 0.04 0.04
SPT5H_MOUSE Transcription elongation factor SPT5; OS = Mus musculus, GN = Supt5h, PE = 1, SV = 1 32 120589 4.93 4 1 4 1 4 0.06 0.04
GPX8_MOUSE Probable glutathione peroxidase 8; OS = Mus musculus, GN = Gpx8, PE = 1, SV = 1 32 24133 9.42 2 1 2 1 2 0.11 0.19
COR1C_MOUSE Coronin-1C; OS = Mus musculus, GN = Coro1c, PE = 1, SV = 2 32 53087 6.65 6 1 4 1 4 0.18 0.08
T126A_MOUSE Transmembrane protein 126A; OS = Mus musculus, GN = Tmem126a, PE = 1, SV = 1 32 21526 9.45 1 1 1 1 1 0.09 0.21
TBD2B_MOUSE TBC1 domain family member 2B; OS = Mus musculus, GN = Tbc1d2b, PE = 1, SV = 2 32 109881 5.74 3 1 3 1 3 0.05 0.04
NDUA9_MOUSE NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial; OS = Mus musculus, GN = Ndufa9, PE = 1, SV = 2 31 42498 9.75 2 1 2 1 2 0.07 0.1
GLMP_MOUSE Glycosylated lysosomal membrane protein; OS = Mus musculus, GN = Glmp, PE = 1, SV = 1 31 43776 5.73 2 1 2 1 2 0.1 0.1
PEF1_MOUSE Peflin; OS = Mus musculus, GN = Pef1, PE = 1, SV = 1 31 29209 5.89 3 1 2 1 2 0.15 0.15
TGM2_MOUSE Protein-glutamine gamma-glutamyltransferase 2; OS = Mus musculus, GN = Tgm2, PE = 1, SV = 4 31 77012 4.98 3 1 3 1 3 0.05 0.06
STXB3_MOUSE Syntaxin-binding protein 3; OS = Mus musculus, GN = Stxbp3, PE = 1, SV = 1 31 67899 8.28 1 1 1 1 1 0.03 0.06
APEH_MOUSE Acylamino-acid-releasing enzyme; OS = Mus musculus, GN = Apeh, PE = 1, SV = 3 31 81529 5.36 5 2 5 2 5 0.14 0.11
UFSP2_MOUSE Ufm1-specific protease 2; OS = Mus musculus, GN = Ufsp2, PE = 1, SV = 1 31 52482 6.28 1 1 1 1 1 0.05 0.08
CD166_MOUSE CD166 antigen; OS = Mus musculus, GN = Alcam, PE = 1, SV = 3 31 65051 5.85 4 1 3 1 3 0.1 0.07
HIG1A_MOUSE HIG1 domain family member 1A, mitochondrial; OS = Mus musculus, GN = Higd1a, PE = 1, SV = 1 31 10418 9.79 1 1 1 1 1 0.23 0.47
CYTB_MOUSE Cystatin-B; OS = Mus musculus, GN = Cstb, PE = 1, SV = 1 31 11039 6.82 7 2 3 2 3 0.21 1.09
TIMP1_MOUSE Metalloproteinase inhibitor 1; OS = Mus musculus, GN = Timp1, PE = 1, SV = 2 31 22613 9.14 3 1 3 1 3 0.27 0.2
SNP29_MOUSE Synaptosomal-associated protein 29; OS = Mus musculus, GN = Snap29, PE = 1, SV = 1 31 29554 5.23 1 1 1 1 1 0.04 0.15
CDV3_MOUSE Protein CDV3; OS = Mus musculus, GN = Cdv3, PE = 1, SV = 2 30 29711 5.84 2 1 2 1 2 0.22 0.15
FUBP1_MOUSE Far upstream element-binding protein 1; OS = Mus musculus, GN = Fubp1, PE = 1, SV = 1 30 68497 7.74 5 1 4 1 4 0.1 0.06
FEN1_MOUSE Flap endonuclease 1; OS = Mus musculus, GN = Fen1, PE = 1, SV = 1 30 42288 8.54 1 1 1 1 1 0.07 0.1
AAAT_MOUSE Neutral amino acid transporter B(0); OS = Mus musculus, GN = Slc1a5, PE = 1, SV = 2 30 58445 8.14 5 1 4 1 4 0.08 0.07
EMB_MOUSE Embigin; OS = Mus musculus, GN = Emb, PE = 1, SV = 2 30 37041 5.7 1 1 1 1 1 0.03 0.12
S2611_MOUSE Sodium-independent sulfate anion transporter; OS = Mus musculus, GN = Slc26a11, PE = 2, SV = 2 30 64068 7.56 1 1 1 1 1 0.05 0.07
BIEA_MOUSE Biliverdin reductase A; OS = Mus musculus, GN = Blvra, PE = 1, SV = 1 30 33504 6.53 4 1 3 1 3 0.19 0.13
TPD54_MOUSE Tumor protein D54 OS = Mus musculus GN = Tpd52l2 PE = 1 SV = 1 30 24028 5.8 2 1 2 1 2 0.18 0.19
SHIP2_MOUSE Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2; OS = Mus musculus, GN = Inppl1, PE = 1, SV = 1 30 138887 6.11 4 1 4 1 3 0.05 0.03
LTOR5_MOUSE Ragulator complex protein LAMTOR5; OS = Mus musculus, GN = Lamtor5, PE = 1, SV = 1 30 9636 4.69 2 1 2 1 2 0.44 0.52
ZNT7_MOUSE Zinc transporter 7; OS = Mus musculus, GN = Slc30a7, PE = 1, SV = 1 28 41763 6.33 5 2 4 2 4 0.19 0.22
COX6C_MOUSE Cytochrome c oxidase subunit 6C; OS = Mus musculus, GN = Cox6c, PE = 1, SV = 3 30 8464 10.13 2 1 2 1 2 0.33 0.61
DRG2_MOUSE Developmentally-regulated GTP-binding protein 2; OS = Mus musculus, GN = Drg2, PE = 1, SV = 1 29 40692 9.03 2 2 2 2 2 0.16 0.23
DYST_MOUSE Dystonin; OS = Mus musculus, GN = Dst, PE = 1, SV = 2 29 833701 5.2 22 2 22 2 22 0.05 0.01
PSMG1_MOUSE Proteasome assembly chaperone 1; OS = Mus musculus, GN = Psmg1, PE = 1, SV = 1 29 33083 6.05 4 2 2 2 2 0.15 0.29
FBN1_MOUSE Fibrillin-1; OS = Mus musculus, GN = Fbn1, PE = 1, SV = 2 29 312083 4.8 27 1 24 1 24 0.19 0.01
DAG1_MOUSE Dystroglycan; OS = Mus musculus, GN = Dag1, PE = 1, SV = 4 29 96844 8.59 4 1 3 1 3 0.04 0.04
SNX5_MOUSE Sorting nexin-5; OS = Mus musculus, GN = Snx5, PE = 1, SV = 1 29 46768 6.19 5 1 5 1 5 0.17 0.09
TIM8B_MOUSE Mitochondrial import inner membrane translocase subunit Tim8 B; OS = Mus musculus, GN = Timm8b, PE = 1, SV = 1 29 9281 5.02 1 1 1 1 1 0.13 0.54
PLCB3_MOUSE 1-Phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; OS = Mus musculus, GN = Plcb3, PE = 1, SV = 2 29 139400 5.7 6 1 6 1 6 0.09 0.03
RTCB_MOUSE tRNA-splicing ligase RtcB homolog; OS = Mus musculus, GN = Rtcb, PE = 1, SV = 1 28 55214 6.77 5 2 4 2 4 0.19 0.16
TM9S4_MOUSE Transmembrane 9 superfamily member 4; OS = Mus musculus, GN = Tm9sf4, PE = 1, SV = 1 28 74644 6.86 1 1 1 1 1 0.03 0.06
MBOA7_MOUSE Lysophospholipid acyltransferase 7; OS = Mus musculus, GN = Mboat7, PE = 1, SV = 1 28 53400 8.96 2 1 1 1 1 0.05 0.08
ARPC3_MOUSE Actin-related protein 2/3 complex subunit 3; OS = Mus musculus, GN = Arpc3, PE = 1, SV = 3 28 20511 8.78 3 1 3 1 3 0.24 0.22
RL27A_MOUSE 60S ribosomal protein L27a; OS = Mus musculus, GN = Rpl27a, PE = 1, SV = 5 28 16595 11.12 11 2 4 1 4 0.29 0.28
JAK1_MOUSE Tyrosine-protein kinase JAK1; OS = Mus musculus, GN = Jak1, PE = 1, SV = 1 28 133282 7.63 10 2 6 2 6 0.08 0.06
TBL1R_MOUSE F-box-like/WD repeat-containing protein TBL1XR1; OS = Mus musculus, GN = Tbl1xr1, PE = 1, SV = 1 28 55626 5.33 4 1 2 1 2 0.1 0.08
PIPNA_MOUSE Phosphatidylinositol transfer protein alpha isoform; OS = Mus musculus, GN = Pitpna, PE = 1, SV = 2 28 31873 5.97 2 1 2 1 2 0.13 0.14
GLGB_MOUSE 1,4-Alpha-glucan-branching enzyme; OS = Mus musculus, GN = Gbe1, PE = 1, SV = 1 28 80313 5.97 2 2 1 1 1 0.02 0.05
CY24B_MOUSE Cytochrome b-245 heavy chain; OS = Mus musculus, GN = Cybb, PE = 1, SV = 1 27 65262 7.83 1 1 1 1 1 0.05 0.07
SNX7_MOUSE Sorting nexin-7; OS = Mus musculus, GN = Snx7, PE = 1, SV = 1 27 44971 4.99 3 2 2 1 2 0.14 0.1
CSN8_MOUSE COP9 signalosome complex subunit 8; OS = Mus musculus, GN = Cops8, PE = 1, SV = 1 27 23241 5.09 3 1 3 1 3 0.38 0.19
MTNA_MOUSE Methylthioribose-1-phosphate isomerase; OS = Mus musculus, GN = Mri1, PE = 1, SV = 1 27 39386 5.6 3 2 3 2 3 0.25 0.23
SIR2_MOUSE NAD-dependent protein deacetylase sirtuin-2; OS = Mus musculus, GN = Sirt2, PE = 1, SV = 2 27 43228 5.23 1 1 1 1 1 0.06 0.1
QCR7_MOUSE Cytochrome b-c1 complex subunit 7 OS = Mus musculus, GN = Uqcrb, PE = 1, SV = 3 27 13519 9.1 2 1 2 1 2 0.21 0.35
ERBIN_MOUSE Erbin; OS = Mus musculus, GN = Erbin, PE = 1, SV = 3 27 157150 5.46 4 1 4 1 4 0.05 0.03
TTL12_MOUSE Tubulin–tyrosine ligase-like protein 12; OS = Mus musculus, GN = Ttll12, PE = 1, SV = 1 27 73996 5.39 3 1 2 1 2 0.07 0.06
FBLN3_MOUSE EGF-containing fibulin-like extracellular matrix protein 1 27 54916 5.01 4 1 3 1 3 0.1 0.08
PYRD_MOUSE Dihydroorotate dehydrogenase (quinone), mitochondrial 27 42674 9.56 1 1 1 1 1 0.06 0.1
COMD2_MOUSE COMM domain-containing protein 2 26 22834 6.14 3 1 3 1 3 0.28 0.2
CBR1_MOUSE Carbonyl reductase [NADPH] 1 26 30622 8.53 2 1 2 1 2 0.07 0.14
CTL1_MOUSE Choline transporter-like protein 1 26 73018 9.04 4 1 4 1 4 0.06 0.06
CD47_MOUSE Leukocyte surface antigen CD47 26 33076 8.93 2 1 2 1 2 0.14 0.13
DJC24_MOUSE DnaJ homolog subfamily C member 24 26 22066 5.63 2 1 2 1 2 0.17 0.21
ACOD2_MOUSE Acyl-CoA desaturase 2 26 40890 9.14 2 1 2 1 2 0.13 0.11
PROS_MOUSE Vitamin K-dependent protein S 26 74886 5.61 8 1 5 1 5 0.11 0.06
TTYH2_MOUSE Protein tweety homolog 2 26 58969 5.67 2 1 2 1 2 0.05 0.07
IF2P_MOUSE Eukaryotic translation initiation factor 5B 26 137532 5.47 10 2 9 2 9 0.14 0.06
MCA3_MOUSE Eukaryotic translation elongation factor 1 epsilon-1 26 19846 8.6 1 1 1 1 1 0.06 0.23
TM214_MOUSE Transmembrane protein 214 26 76381 9.41 5 1 5 1 5 0.16 0.06
S10AA_MOUSE Protein S100-A10 26 11179 6.27 4 1 1 1 1 0.27 0.44
ARAP1_MOUSE Arf-GAP with Rho-GAP domain, ANK repeat and pH domain-containing protein 1 25 162174 5.81 2 1 2 1 2 0.03 0.03
LMF2_MOUSE Lipase maturation factor 2 25 79947 9.99 1 1 1 1 1 0.02 0.05
OLR1_MOUSE Oxidized low-density lipoprotein receptor 1 25 41617 7.55 2 1 2 1 2 0.09 0.11
UCRI_MOUSE Cytochrome b-c1 complex subunit Rieske, mitochondrial 25 29349 8.91 2 2 1 1 1 0.09 0.15
MPPA_MOUSE Mitochondrial-processing peptidase subunit alpha 25 58242 6.36 2 1 2 1 2 0.06 0.07
ARFG1_MOUSE ADP-ribosylation factor GTPase-activating protein 1 25 45260 5.39 2 1 2 1 2 0.08 0.1
UBP24_MOUSE Ubiquitin carboxyl-terminal hydrolase 24 25 293814 5.82 4 1 4 1 4 0.03 0.01
AIMP1_MOUSE Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 25 33976 8.57 3 1 2 1 2 0.15 0.13
STX17_MOUSE Syntaxin-17 25 33201 6.28 2 1 2 1 2 0.15 0.13
TM165_MOUSE Transmembrane protein 165 25 34768 6.97 7 1 3 1 3 0.25 0.13
ACOT2_MOUSE Acyl-coenzyme A thioesterase 2, mitochondrial 25 49626 6.88 1 1 1 1 1 0.06 0.09
SPD2B_MOUSE SH3 and PX domain-containing protein 2B 25 101454 8.78 3 1 3 1 3 0.07 0.04
VP13C_MOUSE Vacuolar protein sorting-associated protein 13C 25 419824 6.37 10 1 8 1 8 0.04 0.01
LAP2B_MOUSE Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma 25 50342 9.45 7 1 7 1 7 0.24 0.09
T106A_MOUSE Transmembrane protein 106A 25 29091 7.07 5 1 2 1 2 0.16 0.15
NRP2_MOUSE Neuropilin-2 24 104565 5.07 2 1 2 1 2 0.04 0.04
VISTA_MOUSE V-type immunoglobulin domain-containing suppressor of T cell activation 24 33538 7.21 2 1 1 1 1 0.04 0.13
LYPA1_MOUSE Acyl-protein thioesterase 1 24 24671 6.14 2 1 1 1 1 0.17 0.18
RIOK3_MOUSE Serine/threonine-protein kinase RIO3 24 58667 5.47 4 1 3 1 3 0.09 0.07
RFA1_MOUSE Replication protein A 70 kDa DNA-binding subunit 24 68994 8.13 5 1 4 1 4 0.11 0.06
SRRM1_MOUSE Serine/arginine repetitive matrix protein 1 24 106798 11.87 8 1 6 1 6 0.12 0.04
GVIN1_MOUSE Interferon-induced very large GTPase 1 24 280637 6.12 5 1 5 1 5 0.03 0.02
INO1_MOUSE Inositol-3-phosphate synthase 1 24 60893 5.99 3 1 3 1 3 0.1 0.07
ADAS_MOUSE Alkyldihydroxyacetonephosphate synthase, peroxisomal 24 71638 7.25 2 1 2 1 2 0.06 0.06
CASP3_MOUSE Caspase-3 24 31454 6.45 3 1 3 1 3 0.18 0.14
RIDA_MOUSE 2-Iminobutanoate/2-iminopropanoate deaminase 24 14247 8.74 4 2 2 1 2 0.19 0.33
ARFG2_MOUSE ADP-ribosylation factor GTPase-activating protein 2 24 56563 8.36 3 1 3 1 3 0.14 0.08
DHC24_MOUSE Delta(24)-sterol reductase 24 60073 8.42 8 1 7 1 7 0.2 0.07
RT16_MOUSE 28S ribosomal protein S16, mitochondrial 24 15182 9.74 1 1 1 1 1 0.15 0.31
PTH_MOUSE Probable peptidyl-tRNA hydrolase 24 22147 9.92 1 1 1 1 1 0.1 0.2
SWP70_MOUSE Switch-associated protein 70 23 68953 5.78 2 1 2 1 2 0.07 0.06
VWA8_MOUSE von Willebrand factor A domain-containing protein 8 23 213287 6.14 8 1 7 1 7 0.08 0.02
UBXN4_MOUSE UBX domain-containing protein 4 23 56437 6.23 5 1 4 1 4 0.23 0.08
AEBP1_MOUSE Adipocyte enhancer-binding protein 1 23 128284 5.02 6 1 5 1 5 0.09 0.03
GCR_MOUSE Glucocorticoid receptor 23 85998 5.99 8 1 7 1 7 0.1 0.05
IAH1_MOUSE Isoamyl acetate-hydrolyzing esterase 1 homolog 23 27956 5.34 3 1 2 1 2 0.12 0.16
VPS16_MOUSE Vacuolar protein sorting-associated protein 16 homolog 22 94868 6.56 6 2 5 1 5 0.1 0.05
LY6C1_MOUSE Lymphocyte antigen 6C1 22 14183 5.76 2 1 2 1 2 0.29 0.33
BCAT1_MOUSE Branched-chain-amino-acid aminotransferase, cytosolic 22 42764 5.25 3 1 3 1 3 0.12 0.1
E2AK2_MOUSE Interferon-induced, double-stranded RNA-activated protein kinase 22 58243 8.76 1 1 1 1 1 0.05 0.07
FLII_MOUSE Protein flightless-1 homolog 21 144712 5.75 9 1 9 1 9 0.1 0.03
CHCH2_MOUSE Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 21 15651 9.78 2 1 2 1 2 0.24 0.3
TNPO2_MOUSE Transportin-2 21 100391 4.85 7 1 6 1 4 0.14 0.04
UBFD1_MOUSE Ubiquitin domain-containing protein UBFD1 21 40118 8.98 7 1 4 1 4 0.2 0.11
WWOX_MOUSE WW domain-containing oxidoreductase 21 46483 6.54 2 1 2 1 2 0.11 0.09
DYR_MOUSE Dihydrofolate reductase 21 21592 8.56 3 1 2 1 2 0.23 0.21
ARHG1_MOUSE Rho guanine nucleotide exchange factor 1 21 102741 5.43 3 1 3 1 3 0.06 0.04
ATX2L_MOUSE Ataxin-2-like protein 20 110580 8.94 2 1 2 1 2 0.05 0.04
PSD10_MOUSE 26S proteasome non-ATPase regulatory subunit 10 20 25068 5.68 1 1 1 1 1 0.06 0.18
TMF1_MOUSE TATA element modulatory factor 20 121729 4.83 5 2 3 1 3 0.06 0.03
ANFY1_MOUSE Rabankyrin-5 20 128571 5.58 5 2 4 1 4 0.07 0.03
MAGD1_MOUSE Melanoma-associated antigen D1 20 85617 7.01 5 1 4 1 4 0.1 0.05
YIF1A_MOUSE Protein YIF1A 19 32114 9.11 1 1 1 1 1 0.05 0.14
TR10B_MOUSE Tumor necrosis factor receptor superfamily member 10B 19 42138 6.75 4 1 3 1 3 0.13 0.1
QCR8_MOUSE Cytochrome b-c1 complex subunit 8 19 9762 10.26 1 1 1 1 1 0.28 0.51
ATP5J_MOUSE ATP synthase-coupling factor 6, mitochondrial 18 12489 9.36 6 1 4 1 4 0.4 0.38
YAP1_MOUSE Transcriptional coactivator YAP1 18 52351 4.96 1 1 1 1 1 0.05 0.08
PARP9_MOUSE Poly [ADP-ribose] polymerase 9 17 96597 6.68 3 1 3 1 3 0.09 0.04
MTCH2_MOUSE Mitochondrial carrier homolog 2 17 33477 8.59 1 1 1 1 1 0.07 0.13
NXN_MOUSE Nucleoredoxin 17 48314 4.84 1 1 1 1 1 0.06 0.09
  • aProtein score is calculated from the score of the peptide attributed to the protein. bpI is (predicted) isoelectric point. cNumber of matches is spectrum number matched to protein #1. dNumber of significant matches is spectrum number that matches protein and exceeds the identification criteria. eNumber of sequences is number of peptides matched to protein #2. fNumber of significant sequences is number of peptides exceeding the identification criteria matched to proteins. gNumber of unique sequences is a unique #3 number of peptides matched to proteins. hSequence coverage is the ratio of the total number of matched peptide residues to the total length of the protein. iExponentially modified protein abundance index (http://www.matrixscience.com/help/quant_empai_help.html). #1When multiple spectra are matched to the same peptide, the way of counting into one is called "peptide number". #2When multiple spectra are matched to the same peptide, the method of counting is called "spectrum number". #3"Unique" is a peptide that is not matched to other proteins and has been assigned only to the relevant protein.
Table 2. Identification of endogenous proteins contained in mMSC-AT_P3 (cells passaged 3 times).
UniProt/Swiss-Prot ID Description Protein scorea Protein mass (kDa) pIb Num. of matchesc Num. of significant matchesd Num. of sequencese Num. of significant sequencesf Num. of unique sequencesg Sequence coverageh emPAIi
MYH9_MOUSE Myosin-9 3652 226232 5.54 238 130 81 52 74 0.52 1.93
MYH10_MOUSE Myosin-10 793 228855 5.43 66 31 25 13 18 0.19 0.32
SERPH_MOUSE Serpin H1 3042 46504 8.88 217 141 22 21 22 0.59 7.57
G3P_MOUSE Glyceraldehyde-3-phosphate dehydrogenase 3019 35787 8.44 240 131 15 12 9 0.67 8.1
S10AB_MOUSE Protein S100-A11 2948 11075 5.28 127 109 5 4 3 0.66 37.69
CLH1_MOUSE Clathrin heavy chain 1 2893 191435 5.48 163 110 62 45 62 0.57 1.92
ACTN1_MOUSE Alpha-actinin-1 2445 103004 5.23 136 82 42 31 27 0.65 2.98
ACTN4_MOUSE Alpha-actinin-4 1377 104911 5.25 111 60 36 24 21 0.56 1.82
KPYM_MOUSE Pyruvate kinase PKM 2269 57808 7.18 136 93 33 26 14 0.69 7.7
HS90A_MOUSE Heat shock protein HSP 90-alpha 1754 84735 4.93 181 93 28 22 21 0.52 2.79
ENPL_MOUSE Endoplasmin 1610 92418 4.74 101 64 34 24 16 0.48 2.39
TRAP1_MOUSE Heat shock protein 75 kDa, mitochondrial 123 80159 6.25 6 6 4 4 4 0.11 0.23
ENOA_MOUSE Alpha-enolase 2147 47111 6.37 163 78 20 14 7 0.69 4.37
FLNA_MOUSE Filamin-A 2029 281046 5.68 241 136 64 42 61 0.43 0.93
FLNB_MOUSE Filamin-B 1355 277651 5.46 119 68 56 40 52 0.43 0.86
FLNC_MOUSE Filamin-C 351 290937 5.63 66 26 36 16 31 0.24 0.3
GRP75_MOUSE Stress-70 protein, mitochondrial 961 73416 5.81 123 47 16 11 16 0.36 0.98
UBA1_MOUSE Ubiquitin-like modifier-activating enzyme 1 1729 117734 5.43 87 64 29 22 29 0.58 1.52
TLN1_MOUSE Talin-1 1723 269653 5.84 122 71 43 30 32 0.35 0.64
FAS_MOUSE Fatty acid synthase 1679 272257 6.13 109 68 54 36 54 0.42 0.77
EF2_MOUSE Elongation factor 2 1674 95253 6.41 114 76 31 25 31 0.61 2.27
VIME_MOUSE Vimentin 1667 53655 5.06 152 77 37 26 37 0.67 8.53
ASSY_MOUSE Argininosuccinate synthase 1574 46555 8.36 96 68 22 15 18 0.66 6.84
ANXA2_MOUSE Annexin A2 1565 38652 7.55 126 98 14 11 14 0.54 2.27
VDAC1_MOUSE Voltage-dependent anion-selective channel protein 1 1559 32331 8.55 161 108 13 8 13 0.65 2.18
VDAC2_MOUSE Voltage-dependent anion-selective channel protein 2 312 31713 7.44 76 23 8 6 8 0.42 1.19
DYHC1_MOUSE Cytoplasmic dynein 1 heavy chain 1 1401 531710 6.03 112 64 65 36 65 0.26 0.34
CH60_MOUSE 60 kDa heat shock protein, mitochondrial 1376 60917 5.91 76 42 22 18 22 0.54 2.67
PDIA1_MOUSE Protein disulfide-isomerase 1325 57023 4.77 92 45 19 15 19 0.41 1.99
PLEC_MOUSE Plectin 1320 533861 5.74 113 55 74 36 74 0.26 0.33
TKT_MOUSE Transketolase 1319 67588 7.23 83 61 22 20 22 0.62 2.66
TBB6_MOUSE Tubulin beta-6 chain 846 50058 4.8 83 31 19 13 7 0.61 2.48
ANXA5_MOUSE Annexin A5 1219 35730 4.83 83 50 17 14 15 0.67 6.21
CATB_MOUSE Cathepsin B 1206 37256 5.57 37 31 7 5 7 0.45 1.44
GELS_MOUSE Gelsolin 1190 85888 5.83 68 48 19 15 13 0.56 1.29
GELS_HORSE Gelsolin 546 80777 5.58 33 24 9 6 3 0.28 0.51
IMB1_MOUSE Importin subunit beta-1 1155 97122 4.68 71 53 29 22 29 0.61 2.2
FPPS_MOUSE Farnesyl pyrophosphate synthase 1095 40556 5.49 44 31 14 11 14 0.68 2.43
PSMD2_MOUSE 26S proteasome non-ATPase regulatory subunit 2 1057 100139 5.06 51 39 19 15 19 0.44 0.95
TCPA_MOUSE T-complex protein 1 subunit alpha 1055 60411 5.82 44 31 16 11 16 0.54 1.29
ESTD_MOUSE S-Formylglutathione hydrolase 1044 31299 6.7 53 36 15 11 15 0.79 4.6
ATPA_MOUSE ATP synthase subunit alpha, mitochondrial 1041 59716 9.22 59 42 16 14 4 0.49 2.06
IQGA1_MOUSE Ras GTPase-activating-like protein IQGAP1 1034 188624 6.07 67 37 35 19 35 0.36 0.56
WDR1_MOUSE WD repeat-containing protein 1 1014 66365 6.11 64 42 19 15 19 0.65 1.57
TCPE_MOUSE T-complex protein 1 subunit epsilon 1002 59586 5.72 51 33 15 9 15 0.55 1.16
SPB6_MOUSE Serpin B6 988 42571 5.53 46 35 13 11 13 0.56 2.92
ACLY_MOUSE ATP-citrate synthase 961 119651 7.13 64 44 26 20 26 0.42 1.08
LRP1_MOUSE Prolow-density lipoprotein receptor-related protein 1 939 504411 5.14 76 46 37 25 37 0.16 0.27
CAN2_MOUSE Calpain-2 catalytic subunit 937 79822 4.86 55 37 18 15 17 0.53 1.31
ALDOA_MOUSE Fructose-bisphosphate aldolase A 923 39331 8.31 75 49 15 13 15 0.62 3.89
SPTB2_MOUSE Spectrin beta chain, nonerythrocytic 1 900 274052 5.4 74 42 33 21 33 0.24 0.38
LDHA_MOUSE L-Lactate dehydrogenase A chain 888 36475 7.62 64 43 17 12 13 0.68 3.92
LDHB_MOUSE L-Lactate dehydrogenase B chain 144 36549 5.7 9 6 3 3 3 0.19 0.41
1433B_MOUSE 14-3-3 protein beta/alpha 483 28069 4.77 30 19 8 5 4 0.5 1.81
TCPZ_MOUSE T-complex protein 1 subunit zeta 854 57968 6.63 51 37 13 10 13 0.41 1.05
COF1_MOUSE Cofilin-1 795 18548 8.22 57 34 12 9 11 0.68 6.37
COF2_MOUSE Cofilin-2 363 18698 7.66 17 10 5 5 4 0.46 2.01
SYAC_MOUSE Alanine–tRNA ligase, cytoplasmic 785 106841 5.45 46 33 19 13 19 0.35 0.66
PLST_MOUSE Plastin-3 784 70697 5.42 56 35 21 15 21 0.54 1.42
ANXA1_MOUSE Annexin A1 774 38710 6.97 49 30 11 9 11 0.46 1.92
THIO_MOUSE Thioredoxin 767 11668 4.8 33 19 7 3 7 0.78 1.85
PRDX6_MOUSE Peroxiredoxin-6 751 24855 5.71 40 28 11 8 11 0.61 2.78
SPTN1_MOUSE Spectrin alpha chain, nonerythrocytic 1 749 284422 5.2 77 34 42 24 42 0.27 0.42
LEG1_MOUSE Galectin-1 735 14856 5.32 56 36 11 9 11 0.82 26.15
TCPH_MOUSE T-complex protein 1 subunit eta 734 59614 7.95 38 26 16 12 16 0.5 1.48
HNRPF_MOUSE Heterogeneous nuclear ribonucleoprotein F 710 45701 5.31 33 25 9 7 3 0.46 1.27
EF1G_MOUSE Elongation factor 1-gamma 689 50029 6.31 44 28 15 13 15 0.57 1.95
PDIA3_MOUSE Protein disulfide-isomerase A3 682 56643 5.88 64 37 23 16 14 0.54 2.5
TENA_MOUSE Tenascin 679 231659 4.77 33 23 17 11 17 0.16 0.22
ATPB_MOUSE ATP synthase subunit beta, mitochondrial 676 56265 5.19 69 33 23 15 7 0.74 2.27
RCN2_MOUSE Reticulocalbin-2 663 37248 4.28 23 20 9 8 9 0.46 1.44
TCPB_MOUSE T-complex protein 1 subunit beta 654 57441 5.97 32 19 17 12 17 0.49 1.39
LYAG_MOUSE Lysosomal alpha-glucosidase 630 106180 5.53 45 34 16 13 16 0.34 0.81
CKAP4_MOUSE Cytoskeleton-associated protein 4 626 63654 5.46 41 23 14 7 14 0.38 0.58
DPYL2_MOUSE Dihydropyrimidinase-related protein 2 626 62239 5.95 47 26 24 13 21 0.63 1.39
DPYL3_MOUSE Dihydropyrimidinase-related protein 3 602 61897 6.04 26 19 15 8 12 0.57 0.96
ESYT1_MOUSE Extended synaptotagmin-1 621 121478 5.63 25 21 9 7 9 0.19 0.27
NEDD4_MOUSE E3 ubiquitin-protein ligase NEDD4 611 102642 5.12 40 26 17 13 17 0.31 0.77
SYVC_MOUSE Valine–tRNA ligase 604 140127 7.9 37 26 14 9 14 0.24 0.35
GSTO1_MOUSE Glutathione S-transferase omega-1 600 27480 6.92 50 30 13 7 13 0.65 2.87
SEPT2_MOUSE Septin-2 599 41499 6.1 24 19 9 8 8 0.38 1.46
6PGD_MOUSE 6-Phosphogluconate dehydrogenase, decarboxylating 599 53213 6.81 50 32 18 12 18 0.63 2
RPN1_MOUSE Dolichyl-diphosphooligosaccharide–protein glycosyltransferase subunit 1 597 68486 6.02 35 22 15 11 15 0.4 0.96
NUCL_MOUSE Nucleolin 588 76677 4.69 37 22 15 9 15 0.27 0.63
GDIB_MOUSE Rab GDP dissociation inhibitor beta 583 50505 5.93 40 26 13 10 11 0.45 1.48
TPM4_MOUSE Tropomyosin alpha-4 chain 581 28450 4.65 51 29 10 9 10 0.44 3.3
PPCE_MOUSE Prolyl endopeptidase 572 80700 5.44 30 21 12 10 12 0.29 0.68
NCPR_MOUSE NADPH–cytochrome P450 reductase 570 76995 5.34 31 19 13 8 13 0.34 0.54
CISY_MOUSE Citrate synthase, mitochondrial 563 51703 8.72 28 24 12 11 12 0.44 2.09
DDX3X_MOUSE ATP-dependent RNA helicase DDX3X 555 73056 6.73 28 21 12 8 12 0.32 0.58
P5CS_MOUSE Delta-1-pyrroline-5-carboxylate synthase 553 87212 7.18 26 18 10 5 10 0.2 0.27
MBB1A_MOUSE Myb-binding protein 1A 547 151942 9.08 35 21 17 10 17 0.23 0.32
EF1B_MOUSE Elongation factor 1-beta 546 24678 4.53 29 24 9 9 9 0.57 3.53
UGGG1_MOUSE UDP-glucose:glycoprotein glucosyltransferase 1 545 176323 5.4 49 29 23 14 23 0.29 0.46
RPN2_MOUSE Dolichyl-diphosphooligosaccharide–protein glycosyltransferase subunit 2 542 69020 5.54 27 19 12 11 12 0.37 0.94
HS105_MOUSE Heat shock protein 105 kDa 541 96346 5.39 27 17 16 11 15 0.29 0.61
HSP74_MOUSE Heat shock 70 kDa protein 4 440 94073 5.15 26 20 17 16 2 0.3 1.04
PROF1_MOUSE Profilin-1 536 14948 8.46 79 30 8 7 8 0.61 19.18
GANAB_MOUSE Neutral alpha-glucosidase AB 523 106844 5.67 49 27 20 15 20 0.46 0.8
THIC_MOUSE Acetyl-CoA acetyltransferase, cytosolic 523 41271 7.16 30 20 8 6 8 0.5 0.83
ANXA6_MOUSE Annexin A6 518 75837 5.34 39 20 19 10 19 0.4 0.73
P4HA1_MOUSE Prolyl 4-hydroxylase subunit alpha-1 510 60872 5.62 32 26 13 10 13 0.44 1.13
NDKB_MOUSE Nucleoside diphosphate kinase B 508 17352 6.97 31 19 7 4 4 0.63 2.27
KAD1_MOUSE Adenylate kinase isoenzyme 1 499 21526 5.67 26 19 8 5 8 0.57 1.61
SAP_MOUSE Prosaposin 497 61381 5.07 48 30 11 5 11 0.31 0.72
PGH1_MOUSE Prostaglandin G/H synthase 1 491 68998 6.36 29 21 10 8 10 0.21 0.72
HMCS1_MOUSE Hydroxymethylglutaryl-CoA synthase, cytoplasmic 487 57532 5.65 31 22 15 13 15 0.49 1.76
CAP1_MOUSE Adenylyl cyclase-associated protein 1 478 51532 7.16 39 22 11 8 11 0.36 0.91
MK01_MOUSE Mitogen-activated protein kinase 1 474 41249 6.5 21 16 7 5 6 0.44 0.65
ARF4_MOUSE ADP-ribosylation factor 4 470 20384 6.59 35 20 12 8 6 0.8 6.52
2AAA_MOUSE Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 470 65281 5 22 15 14 11 14 0.42 1.02
CPNS1_MOUSE Calpain small subunit 1 469 28445 5.41 24 18 6 5 6 0.39 1.4
FSCN1_MOUSE Fascin 463 54474 6.44 37 22 14 10 14 0.51 1.32
PDIA4_MOUSE Protein disulfide-isomerase A4 461 71938 5.16 32 20 15 10 15 0.39 0.79
TSP1_MOUSE Thrombospondin-1 460 129564 4.72 33 15 16 8 15 0.19 0.29
G6PI_MOUSE Glucose-6-phosphate isomerase 459 62727 8.14 35 17 15 9 15 0.47 1.08
NP1L1_MOUSE Nucleosome assembly protein 1-like 1 458 45317 4.36 30 19 11 9 10 0.47 1.51
ADT1_MOUSE ADP/ATP translocase 1 413 32883 9.73 25 19 11 9 5 0.49 3.01
IPO5_MOUSE Importin-5 449 123511 4.82 38 24 22 13 22 0.37 0.61
RINI_MOUSE Ribonuclease inhibitor 440 49784 4.69 21 16 12 9 12 0.55 1.12
AT1A1_MOUSE Sodium/potassium-transporting ATPase subunit alpha-1 436 112910 5.3 19 15 12 10 12 0.2 0.45
GFPT1_MOUSE Glutamine–fructose-6-phosphate aminotransferase [isomerizing] 1 433 78489 6.39 19 14 11 7 11 0.27 0.45
PSA_MOUSE Puromycin-sensitive aminopeptidase 432 103260 5.61 19 12 7 3 7 0.17 0.13
PDIA6_MOUSE Protein disulfide-isomerase A6 424 48070 5 36 26 14 11 14 0.48 1.59
DEST_MOUSE Destrin 421 18509 8.14 26 14 9 7 9 0.54 4.9
MYOF_MOUSE Myoferlin 421 233177 5.83 29 19 19 13 19 0.15 0.31
ALDH2_MOUSE Aldehyde dehydrogenase, mitochondrial 419 56502 7.53 28 16 10 7 10 0.4 0.8
HNRPU_MOUSE Heterogeneous nuclear ribonucleoprotein U 417 87863 5.92 32 20 13 9 13 0.27 0.53
ANXA4_MOUSE Annexin A4 415 35893 5.43 14 10 8 6 8 0.36 1
PDC6I_MOUSE Programmed cell death 6-interacting protein 414 95964 6.15 25 17 14 8 14 0.28 0.48
MARCS_MOUSE Myristoylated alanine-rich C-kinase substrate 413 29644 4.34 65 43 2 1 2 0.15 0.15
CALU_MOUSE Calumenin 308 37041 4.49 29 16 9 8 3 0.44 1.74
VIGLN_MOUSE Vigilin 410 141655 6.43 32 18 19 10 19 0.24 0.34
FBLN2_MOUSE Fibulin-2 409 131746 4.58 20 15 12 9 12 0.18 0.33
OAT_MOUSE Ornithine aminotransferase, mitochondrial 408 48324 6.19 18 12 9 6 9 0.37 0.68
TPP1_MOUSE Tripeptidyl-peptidase 1 404 61304 6.1 9 8 2 2 2 0.1 0.15
RL9_MOUSE 60S ribosomal protein L9 398 21868 9.96 19 15 7 5 7 0.49 2.1
FLII_MOUSE Protein flightless-1 homolog 397 144712 5.75 27 15 15 8 15 0.28 0.3
UGDH_MOUSE UDP-glucose 6-dehydrogenase 397 54797 7.49 35 21 19 13 19 0.6 1.69
ECHA_MOUSE Trifunctional enzyme subunit alpha, mitochondrial 396 82617 9.24 19 13 9 6 9 0.25 0.35
PUR2_MOUSE Trifunctional purine biosynthetic protein adenosine-3 395 107436 6.25 24 14 10 5 10 0.22 0.31
PPIA_MOUSE Peptidyl-prolyl cis-trans isomerase A 393 17960 7.74 31 21 9 8 9 0.65 8.83
6PGL_MOUSE 6-Phosphogluconolactonase 389 27237 5.55 11 8 5 4 5 0.39 0.84
CAND1_MOUSE Cullin-associated NEDD8-dissociated protein 1 385 136245 5.52 46 27 16 10 16 0.3 0.4
GARS_MOUSE Glycine–tRNA ligase 385 81826 6.24 29 17 15 10 15 0.42 0.67
SND1_MOUSE Staphylococcal nuclease domain-containing protein 1 381 102025 7.08 39 20 20 13 20 0.4 0.78
ESYT2_MOUSE Extended synaptotagmin-2 380 94081 7.63 22 14 9 6 9 0.17 0.31
IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytoplasmic 374 46644 6.73 30 16 17 9 16 0.54 1.23
COPB_MOUSE Coatomer subunit beta 371 106998 5.69 35 19 16 12 16 0.31 0.6
CNPY2_MOUSE Protein canopy homolog 2 371 20754 4.95 5 5 2 2 2 0.19 0.49
MYADM_MOUSE Myeloid-associated differentiation marker 371 35261 8.69 32 7 3 2 3 0.14 0.27
SYIC_MOUSE Isoleucine–tRNA ligase, cytoplasmic 368 144179 6.14 33 17 13 8 13 0.19 0.26
DHE3_MOUSE Glutamate dehydrogenase 1, mitochondrial 366 61298 8.05 26 14 12 8 12 0.28 0.85
CLIC1_MOUSE Chloride intracellular channel protein 1 363 26996 5.09 29 19 10 8 10 0.58 2.98
RCN3_MOUSE Reticulocalbin-3 362 37978 4.74 13 7 4 3 4 0.31 0.39
FINC_MOUSE Fibronectin 361 272368 5.39 31 15 14 8 14 0.11 0.13
ADK_MOUSE Adenosine kinase 360 40123 5.84 18 15 7 6 5 0.4 0.86
DHB4_MOUSE Peroxisomal multifunctional enzyme type 2 359 79432 8.76 12 8 5 2 4 0.11 0.11
CALX_MOUSE Calnexin 357 67236 4.5 32 19 14 10 14 0.38 0.86
RLA0_MOUSE 60S acidic ribosomal protein P0 355 34195 5.91 26 19 11 7 11 0.51 1.64
PYRG2_MOUSE CTP synthase 2 190 65473 6.05 12 7 7 3 6 0.27 0.21
CATZ_MOUSE Cathepsin Z 353 33974 6.13 16 11 3 1 3 0.23 0.28
GNAI2_MOUSE Guanine nucleotide-binding protein G(i) subunit alpha-2 352 40463 5.28 17 11 9 6 9 0.36 0.85
CH10_MOUSE 10 kDa heat shock protein, mitochondrial 352 10956 7.93 30 18 5 2 5 0.39 1.09
VATB2_MOUSE V-type proton ATPase subunit B, brain isoform 350 56515 5.57 20 12 10 7 10 0.41 0.68
MDHM_MOUSE Malate dehydrogenase, mitochondrial 346 35589 8.93 37 17 10 8 10 0.43 1.54
MYL9_MOUSE Myosin regulatory light polypeptide 9 192 19841 4.8 15 7 7 5 4 0.62 1.82
ADHX_MOUSE Alcohol dehydrogenase class-3 341 39522 6.97 11 9 6 5 6 0.4 0.69
APT_MOUSE Adenine phosphoribosyltransferase 338 19712 6.31 20 10 7 5 7 0.56 1.84
IPO4_MOUSE Importin-4 338 119198 4.92 24 17 12 8 12 0.21 0.32
AATM_MOUSE Aspartate aminotransferase, mitochondrial 336 47381 9.13 26 14 11 6 11 0.41 0.69
SC31A_MOUSE Protein transport protein Sec31A 334 133486 6.3 24 18 13 10 13 0.21 0.37
MAOX_MOUSE NADP-dependent malic enzyme 329 63913 7.16 35 18 13 10 13 0.47 0.92
NDKA_MOUSE Nucleoside diphosphate kinase A 324 17197 6.84 23 16 5 2 2 0.47 1.05
TAGL2_MOUSE Transgelin-2 323 22381 8.39 18 11 7 6 7 0.49 2.63
PPAC_MOUSE Low molecular weight phosphotyrosine protein phosphatase 323 18180 6.3 9 7 5 3 5 0.44 0.97
P4HA2_MOUSE Prolyl 4-hydroxylase subunit alpha-2 322 60964 5.55 26 19 9 8 9 0.27 0.73
IF4G1_MOUSE Eukaryotic translation initiation factor 4 gamma 1 322 175967 5.3 24 16 11 9 11 0.11 0.27
MRC2_MOUSE C-type mannose receptor 2 321 166968 5.65 32 16 17 9 17 0.21 0.29
DCTN1_MOUSE Dynactin subunit 1 319 141588 5.66 14 10 6 3 6 0.1 0.13
DPYL1_MOUSE Dihydropyrimidinase-related protein 1 317 62129 6.63 9 5 6 2 3 0.17 0.14
MVD1_MOUSE Diphosphomevalonate decarboxylase 315 44044 5.89 11 8 6 5 6 0.34 0.6
PUR9_MOUSE Bifunctional purine biosynthesis protein PURH 315 64177 6.3 19 11 11 7 8 0.31 0.58
SNX9_MOUSE Sorting nexin-9 313 66504 5.35 16 12 8 6 8 0.26 0.46
AR6P1_MOUSE ADP-ribosylation factor-like protein 6-interacting protein 1 312 23421 9.38 6 6 1 1 1 0.14 0.42
XPO2_MOUSE Exportin-2 312 110384 5.52 20 10 12 6 12 0.26 0.26
ANXA3_MOUSE Annexin A3 312 36362 5.5 17 10 6 4 6 0.34 0.58
OST48_MOUSE Dolichyl-diphosphooligosaccharide–protein glycosyltransferase 48 kDa subunit 310 48997 5.52 21 15 9 8 9 0.41 1.34
TCPD_MOUSE T-complex protein 1 subunit delta 310 58030 8.24 15 9 9 6 9 0.29 0.54
PLOD3_MOUSE Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 309 84869 5.81 29 18 17 10 17 0.41 0.64
RL5_MOUSE 60S ribosomal protein L5 308 34379 9.78 14 8 5 4 5 0.33 0.83
CATD_MOUSE Cathepsin D 308 44925 6.71 39 18 10 8 10 0.58 2.04
SC22B_MOUSE Vesicle-trafficking protein SEC22b 307 24725 8.67 18 12 7 4 7 0.6 1.3
PLOD1_MOUSE Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 306 83542 6.08 17 10 10 6 10 0.24 0.42
TCTP_MOUSE Translationally-controlled tumor protein 306 19450 4.76 28 14 6 4 6 0.48 1.89
TCPG_MOUSE T-complex protein 1 subunit gamma 304 60591 6.28 17 12 11 8 11 0.37 0.86
SC23A_MOUSE Protein transport protein Sec23A 303 86106 6.64 10 7 6 3 6 0.16 0.16
SAHH_MOUSE Adenosylhomocysteinase 302 47657 6.08 28 15 11 8 11 0.42 1.01
TCPQ_MOUSE T-complex protein 1 subunit theta 298 59518 5.44 17 8 14 6 14 0.39 0.52
PSMD1_MOUSE 26S proteasome non-ATPase regulatory subunit 1 298 105663 5.25 37 15 15 8 15 0.32 0.37
COCA1_MOUSE Collagen alpha-1(XII) chain 296 340004 5.47 24 7 14 6 14 0.09 0.08
GCN1_MOUSE eIF-2-alpha kinase activator GCN1 295 292834 7.14 22 7 15 4 15 0.1 0.06
USO1_MOUSE General vesicular transport factor p115 295 106917 4.85 20 15 10 5 10 0.22 0.22
UAP1L_MOUSE UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 295 56578 5.27 20 15 7 6 6 0.21 0.56
UAP1_MOUSE UDP-N-acetylhexosamine pyrophosphorylase 93 58572 6.04 10 4 5 2 4 0.12 0.15
PTBP1_MOUSE Polypyrimidine tract-binding protein 1 289 56443 8.47 19 11 9 8 9 0.39 0.81
EIF3A_MOUSE Eukaryotic translation initiation factor 3 subunit A 288 161838 6.38 18 11 10 5 10 0.12 0.14
GSTP1_MOUSE Glutathione S-transferase P 1 286 23594 7.68 31 12 8 5 8 0.74 2.4
SERA_MOUSE D-3-Phosphoglycerate dehydrogenase 279 56549 6.12 15 10 9 7 9 0.32 0.8
GDIR1_MOUSE Rho GDP-dissociation inhibitor 1 279 23393 5.12 29 18 9 6 9 0.42 1.88
VINC_MOUSE Vinculin 278 116644 5.77 27 14 15 10 15 0.26 0.43
PNPH_MOUSE Purine nucleoside phosphorylase 277 32256 5.78 12 8 5 4 5 0.37 0.67
PSMD7_MOUSE 26S proteasome non-ATPase regulatory subunit 7 275 36517 6.29 17 12 8 6 8 0.54 0.98
LRC59_MOUSE Leucine-rich repeat-containing protein 59 274 34856 9.57 14 9 6 2 6 0.32 0.27
UBP14_MOUSE Ubiquitin carboxyl-terminal hydrolase 14 273 55966 5.15 14 11 6 4 6 0.25 0.35
CNN3_MOUSE Calponin-3 272 36406 5.46 20 12 8 6 8 0.45 1.22
SDHA_MOUSE Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 270 72539 7.06 16 11 7 4 7 0.27 0.26
VAT1_MOUSE Synaptic vesicle membrane protein VAT-1 homolog 269 43069 5.95 29 12 10 7 10 0.38 0.97
RLA2_MOUSE 60S acidic ribosomal protein P2 267 11644 4.42 17 10 5 3 5 0.7 1.85
ARLY_MOUSE Argininosuccinate lyase 264 51707 6.48 10 8 5 3 5 0.22 0.38
DDX1_MOUSE ATP-dependent RNA helicase DDX1 263 82448 6.8 18 9 12 6 12 0.29 0.36
PYR1_MOUSE CAD protein 262 243084 6 22 8 14 6 14 0.13 0.11
AATC_MOUSE Aspartate aminotransferase, cytoplasmic 260 46219 6.68 16 7 7 4 7 0.3 0.43
STIP1_MOUSE Stress-induced-phosphoprotein 1 259 62542 6.4 18 8 9 6 9 0.31 0.49
ZYX_MOUSE Zyxin 257 60507 5.99 15 11 5 3 5 0.17 0.32
RL3_MOUSE 60S ribosomal protein L3 257 46081 10.22 18 10 7 5 7 0.25 0.57
CO1A1_MOUSE Collagen alpha-1(I) chain 253 137948 5.65 19 14 9 6 8 0.12 0.24
PCOC1_MOUSE Procollagen C-endopeptidase enhancer 1 253 50136 8.73 11 8 7 4 7 0.33 0.51
RL6_MOUSE 60S ribosomal protein L6 250 33489 10.69 13 9 8 5 8 0.25 0.86
PP1A_MOUSE Serine/threonine-protein phosphatase PP1-alpha catalytic subunit 249 37516 5.94 19 13 8 7 4 0.38 1.17
FUMH_MOUSE Fumarate hydratase, mitochondrial 246 54322 9.12 20 11 8 5 8 0.35 0.59
PCBP2_MOUSE Poly(rC)-binding protein 2 154 38197 6.33 25 11 7 4 5 0.33 0.55
LKHA4_MOUSE Leukotriene A-4 hydrolase 246 69007 5.98 15 10 9 4 9 0.22 0.27
TOM40_MOUSE Mitochondrial import receptor subunit TOM40 homolog 244 37871 7.64 18 10 9 6 9 0.48 0.93
SH3L3_MOUSE SH3 domain-binding glutamic acid-rich-like protein 3 243 10470 5.02 15 10 3 1 3 0.65 1.17
SYNC_MOUSE Asparagine–tRNA ligase, cytoplasmic 242 64238 5.62 22 12 15 6 15 0.38 0.48
PUR6_MOUSE Multifunctional protein ADE2 242 46976 6.94 23 10 10 5 10 0.44 0.7
AL7A1_MOUSE Alpha-aminoadipic semialdehyde dehydrogenase 242 58824 7.16 13 9 6 5 6 0.27 0.43
CP51A_MOUSE Lanosterol 14-alpha demethylase 242 56739 8.6 16 8 9 3 9 0.34 0.25
SYSC_MOUSE Serine–tRNA ligase, cytoplasmic 241 58352 5.95 19 9 10 4 10 0.35 0.33
NDUS1_MOUSE NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 239 79726 5.51 15 10 9 4 9 0.22 0.3
EIF3H_MOUSE Eukaryotic translation initiation factor 3 subunit H 238 39807 6.2 22 14 11 7 11 0.5 1.3
PSB6_MOUSE Proteasome subunit beta type-6 237 25362 4.97 7 7 4 4 4 0.47 0.92
PSA6_MOUSE Proteasome subunit alpha type-6 235 27355 6.34 9 8 3 3 3 0.29 0.58
AMPL_MOUSE Cytosol aminopeptidase 234 56106 7.62 17 9 11 6 11 0.34 0.68
TXND5_MOUSE Thioredoxin domain-containing protein 5 232 46386 5.51 13 7 7 4 7 0.29 0.43
TAGL_MOUSE Transgelin 231 22561 8.85 19 13 8 6 8 0.49 2
AIMP2_MOUSE Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 229 35355 7.7 15 9 6 3 6 0.42 0.42
RET1_MOUSE Retinol-binding protein 1 229 15836 5.1 9 6 4 3 4 0.44 1.17
IPYR_MOUSE Inorganic pyrophosphatase 229 32646 5.37 14 7 7 3 7 0.31 0.46
GSTM2_MOUSE Glutathione S-transferase Mu 2 228 25700 6.9 14 9 7 6 6 0.39 1.62
GSTM1_MOUSE Glutathione S-transferase Mu 1 197 25953 7.71 14 8 5 4 4 0.33 0.89
SYRC_MOUSE Arginine–tRNA ligase, cytoplasmic 228 75625 7.48 23 13 12 7 12 0.24 0.47
WDR61_MOUSE WD repeat-containing protein 61 228 33752 5.1 6 4 3 2 3 0.18 0.28
IMA4_MOUSE Importin subunit alpha-4 178 57737 4.8 10 7 6 4 4 0.32 0.34
RL7_MOUSE 60S ribosomal protein L7 227 31400 10.89 13 7 6 3 5 0.24 0.49
PSME2_MOUSE Proteasome activator complex subunit 2 227 27040 5.54 14 7 5 4 5 0.34 0.84
SCRB2_MOUSE Lysosome membrane protein 2 225 54009 4.99 13 8 6 4 6 0.2 0.36
AT2A2_MOUSE Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 224 114784 5.23 26 12 13 7 13 0.24 0.29
SODM_MOUSE Superoxide dismutase [Mn], mitochondrial 222 24588 8.8 14 8 5 3 5 0.5 0.96
SYLC_MOUSE Leucine–tRNA ligase, cytoplasmic 222 134106 6.64 22 7 13 4 13 0.19 0.13
PTGIS_MOUSE Prostacyclin synthase 222 57011 6.26 28 17 13 9 6 0.52 0.93
PYGB_MOUSE Glycogen phosphorylase, brain form 219 96668 6.28 16 10 9 6 9 0.16 0.3
MPCP_MOUSE Phosphate carrier protein, mitochondrial 218 39606 9.36 15 11 8 5 8 0.32 0.88
LAMP1_MOUSE Lysosome-associated membrane glycoprotein 1 217 43837 8.66 8 7 4 3 4 0.16 0.46
COPA_MOUSE Coatomer subunit alpha 217 138344 7.69 23 11 16 9 16 0.23 0.31
KINH_MOUSE Kinesin-1 heavy chain 216 109484 6.06 13 6 10 4 10 0.19 0.17
LG3BP_MOUSE Galectin-3-binding protein 216 64450 5 12 5 8 5 8 0.29 0.38
PSB4_MOUSE Proteasome subunit beta type-4 215 29097 5.47 5 3 3 2 3 0.23 0.33
IDI1_MOUSE Isopentenyl-diphosphate delta-isomerase 1 215 26272 5.79 19 12 8 7 8 0.54 2.01
CNN2_MOUSE Calponin-2 215 33134 7.53 17 9 9 4 9 0.59 1.12
NAA15_MOUSE N-Alpha-acetyltransferase 15, NatA auxiliary subunit 212 100897 7.68 19 9 9 5 9 0.18 0.23
IF2P_MOUSE Eukaryotic translation initiation factor 5B 212 137532 5.47 16 9 7 4 7 0.14 0.16
LGMN_MOUSE Legumain 211 49341 5.92 10 9 3 3 3 0.17 0.4
DJC10_MOUSE DnaJ homolog subfamily C member 10 210 90525 6.53 15 10 6 3 6 0.13 0.2
PFKAL_MOUSE ATP-dependent 6-phosphofructokinase, liver type 210 85305 6.74 11 8 6 6 6 0.12 0.34
UGPA_MOUSE UTP–glucose-1-phosphate uridylyltransferase 210 56944 7.18 8 6 6 5 6 0.26 0.44
RTN4_MOUSE Reticulon-4 210 126535 4.47 11 9 6 4 6 0.12 0.14
CD34_MOUSE Hematopoietic progenitor cell antigen CD34 208 40957 5.2 3 3 1 1 1 0.05 0.11
TPP2_MOUSE Tripeptidyl-peptidase 2 208 139790 6.13 15 8 9 4 9 0.16 0.13
PCNA_MOUSE Proliferating cell nuclear antigen 208 28766 4.66 15 8 8 6 8 0.63 1.37
TSPO_MOUSE Translocator protein 205 18829 9.52 12 8 4 2 4 0.46 0.92
SNAA_MOUSE Alpha-soluble NSF attachment protein 202 33168 5.3 13 7 7 4 7 0.43 0.65
PDXD1_MOUSE Pyridoxal-dependent decarboxylase domain-containing protein 1 202 87281 5.31 6 4 4 3 4 0.1 0.15
PRDX1_MOUSE Peroxiredoxin-1 202 22162 8.26 43 18 16 7 14 0.69 2.67
DHX9_MOUSE ATP-dependent RNA helicase A 201 149381 6.39 19 12 11 6 11 0.16 0.18
MIC60_MOUSE MICOS complex subunit Mic60 200 83848 6.18 14 8 4 3 4 0.1 0.16
AACS_MOUSE Acetoacetyl-CoA synthetase 199 75152 6.25 24 9 11 7 11 0.36 0.56
SERC_MOUSE Phosphoserine aminotransferase 199 40447 8.15 23 12 11 5 11 0.52 0.85
HYOU1_MOUSE Hypoxia-upregulated protein 1 198 111112 5.12 14 7 9 4 9 0.18 0.21
INF2_MOUSE Inverted formin-2 198 138474 5.09 18 8 10 4 10 0.14 0.13
PSMD6_MOUSE 26S proteasome non-ATPase regulatory subunit 6 197 45507 5.38 4 4 2 2 2 0.1 0.2
AL9A1_MOUSE 4-Trimethylaminobutyraldehyde dehydrogenase 196 53480 6.63 9 6 3 2 3 0.17 0.26
RN213_MOUSE E3 ubiquitin-protein ligase RNF213 196 584411 6.35 23 8 21 7 21 0.07 0.05
CX7A2_MOUSE Cytochrome c oxidase subunit 7A2, mitochondrial 196 9285 10.28 7 6 3 2 3 0.59 1.37
PSB5_MOUSE Proteasome subunit beta type-5 196 28514 6.52 10 8 5 4 5 0.32 0.79
TMX3_MOUSE Protein disulfide-isomerase TMX3 196 51815 5.02 4 4 2 2 2 0.11 0.17
DLDH_MOUSE Dihydrolipoyl dehydrogenase, mitochondrial 195 54238 7.99 16 12 5 4 5 0.21 0.47
AEBP1_MOUSE Adipocyte enhancer-binding protein 1 194 128284 5.02 4 3 2 1 2 0.02 0.03
MP2K1_MOUSE Dual specificity mitogen-activated protein kinase 1 194 43446 6.24 9 5 6 2 5 0.32 0.21
MP2K2_MOUSE Dual specificity mitogen-activated protein kinase 2 191 44374 6.58 5 5 2 2 1 0.12 0.21
STRAP_MOUSE Serine-threonine kinase receptor-associated protein 193 38418 4.99 12 10 6 5 6 0.35 0.72
XPO1_MOUSE Exportin-1 192 123013 5.72 18 10 12 8 12 0.2 0.31
EIF3I_MOUSE Eukaryotic translation initiation factor 3 subunit I 191 36438 5.38 13 8 6 3 6 0.36 0.41
CPNE1_MOUSE Copine-1 190 58849 5.4 11 7 7 4 7 0.3 0.33
EIF3K_MOUSE Eukaryotic translation initiation factor 3 subunit K 189 25070 4.81 7 4 4 3 4 0.33 0.64
MIF_MOUSE Macrophage migration inhibitory factor 189 12496 6.79 13 7 5 3 5 0.63 2.67
CYFP1_MOUSE Cytoplasmic FMR1-interacting protein 1 189 145148 6.46 14 6 10 3 10 0.16 0.09
MYO1C_MOUSE Unconventional myosin-Ic 188 121868 9.41 30 7 18 6 18 0.29 0.23
JAK1_MOUSE Tyrosine-protein kinase JAK1 188 133282 7.63 11 5 6 1 6 0.1 0.03
ARPC2_MOUSE Actin-related protein 2/3 complex subunit 2 188 34336 6.84 14 10 7 4 7 0.41 0.62
CSAD_MOUSE Cysteine sulfinic acid decarboxylase 187 55109 6.17 5 3 3 1 3 0.11 0.08
PA2G4_MOUSE Proliferation-associated protein 2G4 185 43671 6.41 4 4 3 3 3 0.15 0.33
DJB11_MOUSE DnaJ homolog subfamily B member 11 185 40530 5.92 13 7 5 3 5 0.2 0.36
NSDHL_MOUSE Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating 184 40660 7.71 20 8 7 6 7 0.39 0.85
P3H1_MOUSE Prolyl 3-hydroxylase 1 184 83598 5.03 21 11 7 3 7 0.2 0.16
S10AA_MOUSE Protein S100-A10 184 11179 6.27 5 5 2 2 2 0.44 1.06
DHB12_MOUSE Very-long-chain 3-oxoacyl-CoA reductase 182 34719 9.55 15 10 7 5 7 0.45 0.82
SPRC_MOUSE SPARC 182 34428 4.77 11 6 5 3 5 0.25 0.44
DHB7_MOUSE 3-Keto-steroid reductase 179 37293 6.25 5 5 4 4 4 0.21 0.56
MPRD_MOUSE Cation-dependent mannose-6-phosphate receptor 179 31152 5.24 5 4 3 2 3 0.18 0.3
FKB10_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP10 179 64656 5.38 17 7 9 4 9 0.32 0.29
FRIL1_MOUSE Ferritin light chain 1 178 20790 5.66 13 8 4 3 4 0.43 0.81
PGP_MOUSE Glycerol-3-phosphate phosphatase 178 34519 5.21 3 3 1 1 1 0.06 0.13
IMPA1_MOUSE Inositol monophosphatase 1 178 30416 5.08 7 6 3 2 3 0.12 0.31
SYCC_MOUSE Cysteine–tRNA ligase, cytoplasmic 178 94800 6.32 12 5 7 5 7 0.18 0.25
FKBP4_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP4 177 51540 5.54 9 8 3 3 3 0.12 0.27
PPIB_MOUSE Peptidyl-prolyl cis-trans isomerase B 177 23699 9.56 10 5 6 2 6 0.33 0.42
NASP_MOUSE Nuclear autoantigenic sperm protein 177 83903 4.35 10 10 4 4 4 0.14 0.22
MPRI_MOUSE Cation-independent mannose-6-phosphate receptor 177 273639 5.47 14 6 12 4 12 0.1 0.06
NQO1_MOUSE NAD(P)H dehydrogenase [quinone] 1 175 30940 8.74 19 7 5 4 5 0.49 0.71
GCSH_MOUSE Glycine cleavage system H protein, mitochondrial 173 18625 4.78 5 5 1 1 1 0.22 0.55
ITB1_MOUSE Integrin beta-1 173 88173 5.68 22 10 12 6 12 0.29 0.33
CO1A2_MOUSE Collagen alpha-2(I) chain 173 129478 9.27 20 12 10 4 10 0.12 0.14
HNRPM_MOUSE Heterogeneous nuclear ribonucleoprotein M 172 77597 8.8 18 6 11 4 11 0.24 0.24
GHITM_MOUSE Growth hormone-inducible transmembrane protein 172 37250 9.82 5 3 2 1 2 0.09 0.25
TTL12_MOUSE Tubulin–tyrosine ligase-like protein 12 172 73996 5.39 15 7 8 5 8 0.27 0.33
RAB1B_MOUSE Ras-related protein Rab-1B 118 22173 5.55 14 5 7 5 2 0.53 1.53
ACO13_MOUSE Acyl-coenzyme A thioesterase 13 171 15173 8.95 8 7 3 3 3 0.41 1.24
MMP14_MOUSE Matrix metalloproteinase-14 171 65877 8.07 6 5 4 3 4 0.13 0.21
PSA7_MOUSE Proteasome subunit alpha type-7 171 27838 8.59 11 8 6 4 6 0.38 0.81
LEG3_MOUSE Galectin-3 170 27498 8.46 24 11 7 5 7 0.35 1.12
PMVK_MOUSE Phosphomevalonate kinase 169 21902 5.7 2 2 1 1 1 0.1 0.21
TPIS_MOUSE Triosephosphate isomerase 169 32171 5.56 17 7 8 4 8 0.39 0.67
SEPT9_MOUSE Septin-9 168 65534 9.01 11 4 7 3 7 0.22 0.21
UBR4_MOUSE E3 ubiquitin-protein ligase UBR4 167 571927 5.72 24 10 16 6 16 0.07 0.05
GPDM_MOUSE Glycerol-3-phosphate dehydrogenase, mitochondrial 167 80902 6.17 27 10 16 8 16 0.35 0.51
GLCM_MOUSE Glucosylceramidase 166 57585 7.64 28 11 9 6 9 0.39 0.66
LA_MOUSE Lupus La protein homolog 166 47727 9.77 9 7 7 5 7 0.23 0.55
VCAM1_MOUSE Vascular cell adhesion protein 1 166 81265 5.21 7 6 3 3 3 0.07 0.17
AP2A1_MOUSE AP-2 complex subunit alpha-1 165 107596 6.63 18 6 10 5 7 0.19 0.21
HMOX2_MOUSE Heme oxygenase 2 164 35716 5.61 5 2 3 1 3 0.23 0.12
ITAV_MOUSE Integrin alpha-V 164 115287 5.41 15 9 11 7 11 0.16 0.29
ECI1_MOUSE Enoyl-CoA delta isomerase 1, mitochondrial 163 32230 9.12 4 4 2 2 2 0.15 0.29
SYEP_MOUSE Bifunctional glutamate/proline–tRNA ligase 162 169972 7.75 33 10 18 7 18 0.22 0.19
KAD2_MOUSE Adenylate kinase 2, mitochondrial 162 26452 6.96 5 5 2 2 2 0.16 0.37
NOMO1_MOUSE Nodal modulator 1 161 133336 5.75 19 9 11 4 11 0.19 0.13
C1TM_MOUSE Monofunctional C1-tetrahydrofolate synthase, mitochondrial 161 105662 6.58 9 7 4 3 4 0.09 0.13
AKAP2_MOUSE A-kinase anchor protein 2 160 98519 5.13 4 3 3 2 3 0.05 0.09
SFPQ_MOUSE Splicing factor, proline- and glutamine-rich 160 75394 9.45 5 3 2 1 2 0.05 0.06
BACH_MOUSE Cytosolic acyl coenzyme A thioester hydrolase 159 42510 8.9 15 7 9 5 9 0.37 0.63
GLRX1_MOUSE Glutaredoxin-1 159 11863 8.67 7 6 2 1 2 0.47 0.98
DHC24_MOUSE Delta(24)-sterol reductase 159 60073 8.42 16 8 6 4 6 0.23 0.32
NMT1_MOUSE Glycylpeptide N-tetradecanoyltransferase 1 159 56852 8.04 6 5 3 2 3 0.15 0.25
PRDX3_MOUSE Thioredoxin-dependent peroxide reductase, mitochondrial 158 28109 7.15 7 6 4 3 4 0.35 0.56
CAVN1_MOUSE Caveolae-associated protein 1 157 43927 5.43 8 5 4 2 4 0.18 0.21
PALLD_MOUSE Palladin 156 152037 5.87 11 8 7 5 7 0.1 0.15
NPC1_MOUSE Niemann-Pick C1 protein 156 142791 5.44 4 3 2 1 2 0.04 0.03
SRPRB_MOUSE Signal recognition particle receptor subunit beta 156 29561 9.34 4 3 3 2 3 0.16 0.32
PCYOX_MOUSE Prenylcysteine oxidase 156 56459 6.44 10 4 7 3 7 0.27 0.34
TRBM_MOUSE Thrombomodulin 155 61827 4.5 9 8 2 2 2 0.13 0.22
PSB2_MOUSE Proteasome subunit beta type-2 154 22892 6.52 25 11 6 6 6 0.54 1.95
AB1IP_MOUSE Amyloid beta A4 precursor protein-binding family B member 1-interacting protein 154 74272 5.23 13 5 5 2 5 0.14 0.12
AGM1_MOUSE Phosphoacetylglucosamine mutase 154 59415 5.8 8 6 3 2 3 0.13 0.23
APEH_MOUSE Acylamino-acid-releasing enzyme 153 81529 5.36 7 6 5 4 5 0.16 0.23
CATL1_MOUSE Cathepsin L1 153 37523 6.37 12 10 6 4 6 0.44 0.56
ATOX1_MOUSE Copper transport protein ATOX1 151 7334 6.04 8 7 2 1 2 0.53 0.72
ALD2_MOUSE Aldose reductase-related protein 2 151 36098 5.97 11 8 7 5 7 0.36 0.78
PPIC_MOUSE Peptidyl-prolyl cis-trans isomerase C 151 22780 6.96 7 6 4 3 4 0.46 1.07
NRDC_MOUSE Nardilysin 150 132808 4.77 14 6 8 3 8 0.15 0.1
MD2L1_MOUSE Mitotic spindle assembly checkpoint protein MAD2A 150 23583 5.17 6 3 2 1 2 0.17 0.19
BROX_MOUSE BRO1 domain-containing protein BROX 149 46172 7.59 6 4 4 2 4 0.22 0.2
SYTC_MOUSE Threonine–tRNA ligase, cytoplasmic 148 83303 7.03 21 9 13 5 13 0.25 0.29
DNJA1_MOUSE DnaJ homolog subfamily A member 1 148 44839 6.65 14 9 6 4 6 0.31 0.59
NNRE_MOUSE NAD(P)H-hydrate epimerase 147 30953 7.59 11 9 4 3 4 0.3 0.49
CPNE3_MOUSE Copine-3 147 59547 5.52 6 5 3 3 3 0.1 0.23
PTGR1_MOUSE Prostaglandin reductase 1 147 35537 8.09 9 5 4 2 4 0.26 0.42
C1QBP_MOUSE Complement component 1 Q subcomponent-binding protein, mitochondrial 146 30994 4.82 18 8 6 5 6 0.45 0.95
ERG7_MOUSE Lanosterol synthase 145 83088 5.96 13 5 9 3 9 0.23 0.22
PAPS1_MOUSE Bifunctional 3 -phosphoadenosine 5 -phosphosulfate synthase 1 144 70749 6.31 11 4 8 4 8 0.21 0.27
MTPN_MOUSE Myotrophin 143 12853 5.27 11 7 6 3 6 0.62 1.59
VATA_MOUSE V-type proton ATPase catalytic subunit A 143 68283 5.42 16 6 7 3 7 0.25 0.2
ATPG_MOUSE ATP synthase subunit gamma, mitochondrial 143 32865 9.06 7 5 4 2 4 0.26 0.29
DDB1_MOUSE DNA damage-binding protein 1 143 126772 5.14 20 10 11 5 11 0.21 0.18
RL4_MOUSE 60S ribosomal protein L4 143 47124 11.01 16 6 12 5 12 0.37 0.55
NDUB4_MOUSE NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 143 15072 9.89 4 4 1 1 1 0.16 0.31
CRTAP_MOUSE Cartilage-associated protein 143 46140 5.46 12 7 5 4 5 0.2 0.43
TFR1_MOUSE Transferrin receptor protein 1 143 85677 6.13 11 7 3 3 3 0.08 0.16
EI3JA_MOUSE Eukaryotic translation initiation factor 3 subunit J-A 142 29326 4.69 5 3 2 2 2 0.1 0.33
ATLA3_MOUSE Atlastin-3 142 60537 5.73 15 7 10 5 10 0.36 0.41
PUR4_MOUSE Phosphoribosylformylglycinamidine synthase 142 144538 5.43 10 7 8 5 8 0.14 0.16
IPO9_MOUSE Importin-9 142 115978 4.71 16 9 8 5 8 0.2 0.2
PSMD3_MOUSE 26S proteasome non-ATPase regulatory subunit 3 141 60680 8.48 10 8 6 5 6 0.14 0.41
AK1A1_MOUSE Alcohol dehydrogenase [NADP(+)] 141 36564 6.9 5 3 4 2 4 0.27 0.26
DCTN3_MOUSE Dynactin subunit 3 140 20965 5.84 4 3 3 2 3 0.31 0.8
SWP70_MOUSE Switch-associated protein 70 138 68953 5.78 13 7 6 5 6 0.17 0.35
ATPO_MOUSE ATP synthase subunit O, mitochondrial 137 23349 10 7 4 2 2 2 0.17 0.43
UN45A_MOUSE Protein unc-45 homolog A 137 103382 6.01 9 3 7 2 7 0.13 0.08
SCOT1_MOUSE Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial 137 55953 8.73 20 9 10 7 10 0.36 0.68
BCAT1_MOUSE Branched-chain-amino-acid aminotransferase, cytosolic 137 42764 5.25 8 7 3 3 3 0.21 0.48
ASNS_MOUSE Asparagine synthetase [glutamine-hydrolyzing] 137 64241 6.12 16 8 7 4 7 0.19 0.3
PPGB_MOUSE Lysosomal protective protein 136 53809 5.56 7 4 3 2 3 0.1 0.17
PGBM_MOUSE Basement membrane-specific heparan sulfate proteoglycan core protein 136 398039 5.88 25 6 13 2 13 0.07 0.02
CSN7A_MOUSE COP9 signalosome complex subunit 7a 136 30206 7.68 14 7 6 3 6 0.51 0.51
HCD2_MOUSE 3-Hydroxyacyl-CoA dehydrogenase type-2 136 27402 8.53 6 3 4 2 4 0.2 0.35
BZW2_MOUSE Basic leucine zipper and W2 domain-containing protein 2 135 48033 6.26 6 4 3 1 3 0.22 0.19
TOM70_MOUSE Mitochondrial import receptor subunit TOM70 135 67547 7.46 10 7 6 4 4 0.24 0.28
XPP1_MOUSE Xaa-Pro aminopeptidase 1 135 69547 5.33 14 7 7 4 4 0.18 0.27
NXP20_MOUSE Protein Noxp20 135 60975 4.49 6 6 1 1 1 0.07 0.15
PAI1_MOUSE Plasminogen activator inhibitor 1 134 45141 6.17 9 3 7 2 7 0.32 0.2
ROA0_MOUSE Heterogeneous nuclear ribonucleoprotein A0 134 30512 9.35 9 3 4 2 4 0.24 0.31
GORS2_MOUSE Golgi reassembly-stacking protein 2 134 47009 4.68 4 3 3 2 3 0.14 0.19
SMC2_MOUSE Structural maintenance of chromosomes protein 2 131 134156 8.54 8 5 5 2 5 0.06 0.06
RAB21_MOUSE Ras-related protein Rab-21 132 24091 8.11 7 5 5 4 5 0.21 0.99
SAC1_MOUSE Phosphatidylinositide phosphatase SAC1 132 66901 6.85 8 3 5 3 5 0.16 0.21
HSPB1_MOUSE Heat shock protein beta-1 131 23000 6.12 14 9 7 4 7 0.66 1.05
GLU2B_MOUSE Glucosidase 2 subunit beta 131 58756 4.41 9 6 3 2 3 0.12 0.24
IMA1_MOUSE Importin subunit alpha-1 130 57892 5.49 10 5 6 4 6 0.27 0.33
SEC13_MOUSE Protein SEC13 homolog 130 35543 5.15 19 5 4 3 4 0.19 0.42
4F2_MOUSE 4F2 cell-surface antigen heavy chain 130 58300 5.62 5 5 2 2 2 0.1 0.15
CSN4_MOUSE COP9 signalosome complex subunit 4 130 46256 5.57 9 4 6 2 6 0.25 0.2
ROAA_MOUSE Heterogeneous nuclear ribonucleoprotein A/B 129 30812 7.68 11 9 6 6 6 0.2 1.24
ERF3A_MOUSE Eukaryotic peptide chain release factor GTP-binding subunit ERF3A 129 68582 5.12 19 10 9 6 9 0.18 0.44
CUL4A_MOUSE Cullin-4A 128 87697 8.53 4 2 3 2 1 0.07 0.1
CUL4B_MOUSE Cullin-4B 102 110630 8.56 7 3 6 3 4 0.12 0.12
AHSA1_MOUSE Activator of 90 kDa heat shock protein ATPase homolog 1 128 38093 5.41 6 3 4 2 4 0.23 0.24
PDLI1_MOUSE PDZ and LIM domain protein 1 127 35752 6.38 9 5 5 4 5 0.25 0.59
ECHM_MOUSE Enoyl-CoA hydratase, mitochondrial 127 31454 8.76 8 5 5 3 5 0.33 0.49
ITA5_MOUSE Integrin alpha-5 126 114971 5.65 13 6 6 2 6 0.09 0.08
NDUBA_MOUSE NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 126 21010 8.19 6 4 4 3 4 0.31 0.8
RENBP_MOUSE N-Acylglucosamine 2-epimerase 126 49739 5.69 8 5 5 3 5 0.21 0.29
NU155_MOUSE Nuclear pore complex protein Nup155 125 155019 5.77 9 6 5 3 5 0.06 0.08
DDAH1_MOUSE N(G),N(G)-Dimethylarginine dimethylaminohydrolase 1 125 31361 5.64 6 4 5 3 5 0.4 0.49
G6PE_MOUSE GDH/6PGL endoplasmic bifunctional protein 124 88872 6.44 16 3 9 3 9 0.21 0.15
CO5A1_MOUSE Collagen alpha-1(V) chain 124 183564 4.86 7 3 6 2 6 0.09 0.05
PLAP_MOUSE Phospholipase A-2-activating protein 124 87166 5.77 6 2 5 1 5 0.15 0.05
PDLI5_MOUSE PDZ and LIM domain protein 5 123 63259 8.61 15 6 7 3 7 0.21 0.22
NAGAB_MOUSE Alpha-N-acetylgalactosaminidase 122 47204 6.02 7 5 6 4 6 0.23 0.42
PDIA5_MOUSE Protein disulfide-isomerase A5 121 59229 7.25 5 5 4 4 4 0.19 0.33
PSMD5_MOUSE 26S proteasome non-ATPase regulatory subunit 5 121 55937 5.13 12 6 7 4 7 0.26 0.35
FRIH_MOUSE Ferritin heavy chain 120 21053 5.53 9 6 5 3 5 0.48 0.8
OSTF1_MOUSE Osteoclast-stimulating factor 1 119 23768 5.46 6 2 4 1 4 0.19 0.19
PFD5_MOUSE Prefoldin subunit 5 119 17345 5.93 7 4 4 3 4 0.47 1.04
PCKGM_MOUSE Phosphoenolpyruvate carboxykinase [GTP], mitochondrial 119 70482 6.92 16 7 10 7 10 0.26 0.51
SAE2_MOUSE SUMO-activating enzyme subunit 2 119 70525 5.09 8 6 5 4 5 0.21 0.27
NSF_MOUSE Vesicle-fusing ATPase 119 82561 6.52 7 3 7 3 7 0.17 0.16
THY1_MOUSE Thy-1 membrane glycoprotein 118 18069 9.16 9 2 3 1 3 0.25 0.26
RRBP1_MOUSE Ribosome-binding protein 1 117 172776 9.35 12 3 9 3 9 0.1 0.08
CYB5_MOUSE Cytochrome b5 117 15232 4.96 9 4 3 1 3 0.43 1.94
ECI2_MOUSE Enoyl-CoA delta isomerase 2, mitochondrial 117 43240 9.08 4 3 3 2 3 0.13 0.21
TCAF2_MOUSE TRPM8 channel-associated factor 2 117 101532 6.07 5 5 3 3 3 0.06 0.13
RCN1_MOUSE Reticulocalbin-1 117 38090 4.7 9 6 5 3 5 0.27 0.39
ELP1_MOUSE Elongator complex protein 1 117 149489 5.67 9 2 6 1 6 0.09 0.03
NHLC2_MOUSE NHL repeat-containing protein 2 117 78381 5.33 10 6 3 2 3 0.12 0.17
NQO2_MOUSE Ribosyldihydronicotinamide dehydrogenase [quinone] 117 26231 6.54 6 4 4 3 4 0.32 0.61
C1TC_MOUSE C-1-tetrahydrofolate synthase, cytoplasmic 116 101136 6.7 12 7 6 4 6 0.16 0.18
TWF1_MOUSE Twinfilin-1 115 40054 6.21 7 3 7 3 6 0.36 0.37
HPCL1_MOUSE Hippocalcin-like protein 1 115 22324 5.32 5 2 5 2 5 0.43 0.45
PEBP1_MOUSE Phosphatidylethanolamine-binding protein 1 114 20817 5.19 16 6 5 3 5 0.57 0.81
FSTL1_MOUSE Follistatin-related protein 1 114 34532 5.58 1 1 1 1 1 0.06 0.13
TIGAR_MOUSE Fructose-2,6-bisphosphatase TIGAR 114 29172 8.45 3 2 2 1 2 0.16 0.15
HMOX1_MOUSE Heme oxygenase 1 113 32908 6.08 14 6 4 3 4 0.3 0.46
FKB1A_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP1A 112 11915 7.88 10 5 4 3 4 0.66 1.79
GT251_MOUSE Procollagen galactosyltransferase 1 112 71015 6.83 10 5 8 4 8 0.18 0.27
CD81_MOUSE CD81 antigen 111 25797 5.54 5 4 2 2 2 0.18 0.38
IDH3A_MOUSE Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 111 39613 6.27 4 3 3 2 3 0.16 0.23
VMA5A_MOUSE von Willebrand factor A domain-containing protein 5A 111 87087 6.15 6 5 4 3 4 0.09 0.15
LONM_MOUSE Lon protease homolog, mitochondrial 111 105776 6.15 9 4 6 2 6 0.16 0.08
ECHB_MOUSE Trifunctional enzyme subunit beta, mitochondrial 111 51353 9.43 10 2 6 2 6 0.23 0.18
SRPRA_MOUSE Signal recognition particle receptor subunit alpha 110 69579 9.07 6 3 5 2 5 0.12 0.13
EIF3D_MOUSE Eukaryotic translation initiation factor 3 subunit D 109 63948 5.79 8 4 5 2 5 0.2 0.14
CX6A1_MOUSE Cytochrome c oxidase subunit 6A1, mitochondrial 109 12344 9.97 5 4 2 1 2 0.45 0.39
RISC_MOUSE Retinoid-inducible serine carboxypeptidase 108 50932 5.48 16 8 10 6 10 0.3 0.77
PRDX2_MOUSE Peroxiredoxin-2 108 21765 5.2 12 6 6 4 6 0.46 1.13
RL18_MOUSE 60S ribosomal protein L18 108 21631 11.79 2 2 2 2 2 0.14 0.46
PTGR3_MOUSE Prostaglandin reductase-3 108 40503 7.01 6 5 3 3 3 0.23 0.51
PPID_MOUSE Peptidyl-prolyl cis-trans isomerase D 108 40717 7.08 4 2 3 1 3 0.15 0.11
SGTA_MOUSE Small glutamine-rich tetratricopeptide repeat-containing protein alpha 106 34301 4.99 7 6 2 2 2 0.05 0.27
HYEP_MOUSE Epoxide hydrolase 1 106 52543 8.43 28 6 15 3 15 0.43 0.37
RAGP1_MOUSE Ran GTPase-activating protein 1 105 63491 4.59 10 5 8 5 8 0.21 0.39
NCBP1_MOUSE Nuclear cap-binding protein subunit 1 105 91868 6.17 9 3 8 2 8 0.15 0.1
FKBP9_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP9 104 62956 5.03 10 5 6 4 6 0.17 0.3
NB5R3_MOUSE NADH-cytochrome b5 reductase 3 104 34106 8.55 13 5 7 5 7 0.55 0.84
CX6B1_MOUSE Cytochrome c oxidase subunit 6B1 104 10065 8.96 4 3 2 2 2 0.29 1.23
COMT_MOUSE Catechol O-methyltransferase 104 29467 5.52 10 7 4 3 4 0.24 0.53
BIN1_MOUSE Myc box-dependent-interacting protein 1 103 64430 4.95 10 3 7 2 7 0.22 0.14
AN32B_MOUSE Acidic leucine-rich nuclear phosphoprotein 32 family member B 102 31060 3.89 6 3 3 2 3 0.16 0.31
TIF1B_MOUSE Transcription intermediary factor 1-beta 101 88791 5.52 6 4 3 3 3 0.06 0.15
SH3L2_MOUSE SH3 domain-binding glutamic acid-rich-like protein 2 101 12247 5.48 3 3 2 2 2 0.26 0.95
ERO1A_MOUSE ERO1-like protein alpha 101 54050 6.12 8 5 5 4 5 0.15 0.36
LMNA_MOUSE Prelamin-A/C 101 74193 6.54 16 4 11 3 11 0.26 0.18
ODPB_MOUSE Pyruvate dehydrogenase E1 component subunit beta, mitochondrial 101 38912 6.41 6 4 5 4 5 0.29 0.53
MPPA_MOUSE Mitochondrial-processing peptidase subunit alpha 100 58242 6.36 2 1 1 1 1 0.03 0.07
EIF2A_MOUSE Eukaryotic translation initiation factor 2A 100 64363 9.04 8 4 6 3 6 0.2 0.21
GSHR_MOUSE Glutathione reductase, mitochondrial 100 53629 8.19 5 3 3 1 3 0.15 0.08
ADPRH_MOUSE [Protein ADP-ribosylarginine] hydrolase 99 40042 5.46 8 5 3 3 3 0.22 0.37
DDX58_MOUSE Probable ATP-dependent RNA helicase DDX58 99 105908 6.23 9 4 4 2 4 0.09 0.08
AP1M1_MOUSE AP-1 complex subunit mu-1 99 48512 6.82 4 3 2 2 2 0.09 0.19
MVP_MOUSE Major vault protein 98 95865 5.43 11 4 7 3 7 0.18 0.14
COPE_MOUSE Coatomer subunit epsilon 98 34545 4.94 24 6 6 2 6 0.4 0.27
DPP2_MOUSE Dipeptidyl peptidase 2 98 56218 5.17 3 2 2 1 2 0.07 0.08
PURA2_MOUSE Adenylosuccinate synthetase isozyme 2 98 49990 5.98 12 3 7 3 7 0.25 0.28
PGS2_MOUSE Decorin 98 39784 8.87 5 2 3 1 3 0.15 0.11
COPB2_MOUSE Coatomer subunit beta  98 102384 5.17 19 8 12 6 12 0.27 0.28
HCDH_MOUSE Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial 97 34442 8.76 5 3 4 2 4 0.23 0.27
CTBP1_MOUSE C-terminal-binding protein 1 97 47715 6.28 6 3 3 1 3 0.12 0.09
BAG6_MOUSE Large proline-rich protein BAG6 97 120962 5.46 6 2 4 2 4 0.08 0.07
MAP1B_MOUSE Microtubule-associated protein 1B 97 270089 4.76 16 5 13 3 13 0.11 0.05
ATX10_MOUSE Ataxin-10 97 53673 5.12 11 5 5 3 5 0.19 0.26
PRRC1_MOUSE Protein PRRC1 97 46268 5.62 9 4 6 3 6 0.28 0.31
RRAS_MOUSE Ras-related protein R-Ras 97 23749 6.32 4 3 3 2 3 0.22 0.42
CPT1A_MOUSE Carnitine O-palmitoyltransferase 1, liver isoform 97 88195 8.83 4 2 2 2 2 0.09 0.1
SPRE_MOUSE Sepiapterin reductase 97 27865 5.58 3 3 2 2 2 0.22 0.35
NEK7_MOUSE Serine/threonine-protein kinase Nek7 96 34514 8.49 3 2 2 1 2 0.16 0.13
FACE1_MOUSE CAAX prenyl protease 1 homolog 95 54699 6.49 6 2 4 1 4 0.17 0.08
STAM2_MOUSE Signal transducing adapter molecule 2 95 57419 4.94 7 6 3 2 3 0.15 0.24
TMED5_MOUSE Transmembrane emp24 domain-containing protein 5 94 26155 4.81 3 3 1 1 1 0.12 0.17
SYDC_MOUSE Aspartate–tRNA ligase, cytoplasmic 94 57111 6.07 13 3 9 3 9 0.28 0.24
ACADM_MOUSE Medium-chain specific acyl-CoA dehydrogenase, mitochondrial 94 46452 8.6 3 3 2 2 2 0.11 0.2
PDCL3_MOUSE Phosducin-like protein 3 94 27564 4.66 7 5 4 3 4 0.36 0.57
SYWC_MOUSE Tryptophan–tRNA ligase, cytoplasmic 94 54323 6.44 10 4 5 1 5 0.2 0.08
NIBL1_MOUSE Niban-like protein 1 94 84765 5.65 14 8 7 5 7 0.15 0.34
CYB5B_MOUSE Cytochrome b5 type B 94 16308 4.79 3 2 1 1 1 0.23 0.29
TNPO1_MOUSE Transportin-1 93 102291 4.84 17 9 12 6 9 0.28 0.28
SCFD1_MOUSE Sec1 family domain-containing protein 1 93 72277 5.98 8 3 5 3 5 0.19 0.19
PRDX5_MOUSE Peroxiredoxin-5, mitochondrial 93 21884 9.1 13 3 7 3 7 0.48 0.76
PUR8_MOUSE Adenylosuccinate lyase 92 54831 6.9 7 5 6 4 6 0.23 0.36
IAH1_MOUSE Isoamyl acetate-hydrolyzing esterase 1 homolog 92 27956 5.34 3 2 1 1 1 0.07 0.16
VA0D1_MOUSE V-type proton ATPase subunit d 1 91 40275 4.89 5 3 5 3 5 0.33 0.36
CMTD1_MOUSE Catechol O-methyltransferase domain-containing protein 1 91 28943 8.61 2 2 1 1 1 0.1 0.15
AIFM1_MOUSE Apoptosis-inducing factor 1, mitochondrial 90 66724 9.23 4 2 3 2 3 0.1 0.13
MSMO1_MOUSE Methylsterol monooxygenase 1 90 34750 7.29 8 3 5 2 5 0.31 0.43
PON2_MOUSE Serum paraoxonase/arylesterase 2 90 39592 5.49 2 1 2 1 2 0.1 0.11
LTOR3_MOUSE Ragulator complex protein LAMTOR3 90 13544 6.73 4 3 3 2 3 0.4 0.83
ACACA_MOUSE Acetyl-CoA carboxylase 1 90 265088 5.97 12 4 10 3 10 0.09 0.07
PGPI_MOUSE Pyroglutamyl-peptidase 1 90 22919 5.21 4 4 2 2 2 0.21 0.43
CTND1_MOUSE Catenin delta-1 89 104860 6.41 9 6 5 2 5 0.12 0.08
NDUA9_MOUSE NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 89 42498 9.75 6 4 4 2 4 0.16 0.22
PMM2_MOUSE Phosphomannomutase 2 89 27639 6.01 2 2 1 1 1 0.11 0.16
FAAA_MOUSE Fumarylacetoacetase 89 46146 6.7 4 4 3 3 3 0.16 0.31
TCP4_MOUSE Activated RNA polymerase II transcriptional coactivator p15 89 14418 9.6 2 2 1 1 1 0.19 0.33
IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitochondrial 89 50874 8.88 12 4 7 3 6 0.27 0.39
DUS3_MOUSE Dual specificity protein phosphatase 3 89 20459 6.07 2 1 2 1 2 0.19 0.22
LIMA1_MOUSE LIM domain and actin-binding protein 1 88 84008 6.18 6 2 4 1 4 0.09 0.05
MESD_MOUSE LRP chaperone MESD 88 25191 6.06 4 3 3 2 3 0.23 0.39
CYGB_MOUSE Cytoglobin 88 21452 6.32 2 2 1 1 1 0.13 0.21
MA2A1_MOUSE Alpha-mannosidase 2 88 131548 8.17 9 4 8 4 8 0.14 0.14
DPP3_MOUSE Dipeptidyl peptidase 3 88 82846 5.26 11 8 7 5 7 0.22 0.29
NDUC2_MOUSE NADH dehydrogenase [ubiquinone] 1 subunit C2 87 14154 9.24 2 2 1 1 1 0.16 0.33
CNPY4_MOUSE Protein canopy homolog 4 86 28076 4.72 5 3 3 2 3 0.22 0.34
CATH_MOUSE Pro-cathepsin H 86 37146 8.68 3 2 2 1 2 0.14 0.12
PSMD8_MOUSE 26S proteasome non-ATPase regulatory subunit 8 86 39905 9.61 9 3 6 2 6 0.4 0.23
RCC1_MOUSE Regulator of chromosome condensation 86 44903 8.34 5 3 4 2 4 0.19 0.2
ORN_MOUSE Oligoribonuclease, mitochondrial 86 26722 6.67 2 1 2 1 2 0.18 0.17
G6PC3_MOUSE Glucose-6-phosphatase 3 86 38756 8.42 2 2 2 2 2 0.1 0.24
IMA5_MOUSE Importin subunit alpha-5 86 60144 4.93 5 4 2 2 2 0.11 0.15
PSMD4_MOUSE 26S proteasome non-ATPase regulatory subunit 4 86 40678 4.67 7 4 4 2 4 0.17 0.23
GSTT3_MOUSE Glutathione S-transferase theta-3 85 27385 7.63 3 3 1 1 1 0.14 0.16
PSA1_MOUSE Proteasome subunit alpha type-1 85 29528 6 9 6 6 3 6 0.41 0.75
GPNMB_MOUSE Transmembrane glycoprotein NMB 85 63635 7.55 6 4 3 3 3 0.06 0.22
FUBP2_MOUSE Far upstream element-binding protein 2 84 76728 6.9 9 3 6 2 6 0.12 0.12
RS21_MOUSE 40S ribosomal protein S21 84 9136 8.71 6 3 1 1 1 0.17 0.56
ABRAL_MOUSE Costars family protein ABRACL 84 9025 5.52 5 1 2 1 2 0.46 0.56
UMPS_MOUSE Uridine 5 -monophosphate synthase 84 52259 6.17 7 3 3 2 3 0.15 0.17
PSA3_MOUSE Proteasome subunit alpha type-3 84 28387 5.29 3 2 2 1 2 0.11 0.16
HGS_MOUSE Hepatocyte growth factor-regulated tyrosine kinase substrate 83 85961 5.84 10 2 7 2 7 0.17 0.1
RIR1_MOUSE Ribonucleoside-diphosphate reductase large subunit 83 90153 6.27 8 2 6 2 6 0.16 0.1
PGH2_MOUSE Prostaglandin G/H synthase 2 83 68969 7 9 3 6 2 6 0.21 0.13
CSDE1_MOUSE Cold shock domain-containing protein E1 83 88735 5.97 5 1 5 1 5 0.12 0.05
SAE1_MOUSE SUMO-activating enzyme subunit 1 82 38596 5.24 9 6 3 3 3 0.17 0.38
NPS3B_MOUSE Protein NipSnap homolog 3B 82 28290 9.51 3 3 1 1 1 0.11 0.16
TBCD_MOUSE Tubulin-specific chaperone D 82 133236 6.08 5 4 4 3 4 0.08 0.1
COR1C_MOUSE Coronin-1C 82 53087 6.65 7 3 5 3 5 0.17 0.27
SCMC1_MOUSE Calcium-binding mitochondrial carrier protein SCaMC-1 82 52868 7.02 9 4 4 1 4 0.15 0.08
ECM29_MOUSE Proteasome-associated protein ECM29 homolog 82 203573 6.68 21 7 16 6 16 0.18 0.13
LICH_MOUSE Lysosomal acid lipase/cholesteryl ester hydrolase 81 45296 8.16 4 3 3 2 3 0.15 0.2
IMA7_MOUSE Importin subunit alpha-7 81 59926 4.86 9 4 6 4 6 0.29 0.32
CLPT1_MOUSE Cleft lip and palate transmembrane protein 1 homolog 81 75243 5.88 4 1 3 1 3 0.11 0.06
RWDD1_MOUSE RWD domain-containing protein 1 81 27768 4.18 6 4 3 2 3 0.3 0.35
DDX21_MOUSE Nucleolar RNA helicase 2 80 93493 9.19 7 5 3 2 3 0.08 0.09
XPO5_MOUSE Exportin-5 80 136883 5.57 16 8 7 3 7 0.11 0.13
SDCB1_MOUSE Syntenin-1 80 32359 6.66 9 5 4 2 4 0.25 0.29
GLOD4_MOUSE Glyoxalase domain-containing protein 4 80 33296 5.28 8 5 3 2 3 0.19 0.28
PLD3_MOUSE Phospholipase D3 80 54354 6.07 10 4 7 3 7 0.34 0.36
LARP1_MOUSE La-related protein 1 80 121050 8.87 6 3 4 1 4 0.05 0.04
NDUAA_MOUSE NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 80 40578 7.63 2 2 2 2 2 0.09 0.23
EIF3C_MOUSE Eukaryotic translation initiation factor 3 subunit C 80 105465 5.55 14 4 10 3 10 0.18 0.13
GNPI1_MOUSE Glucosamine-6-phosphate isomerase 1 79 32528 6.13 5 3 3 3 3 0.21 0.47
ADDA_MOUSE Alpha-adducin 79 80596 5.62 6 2 4 1 4 0.12 0.05
SEPT5_MOUSE Septin-5 79 42721 6.21 16 5 9 4 9 0.42 0.63
TADBP_MOUSE TAR DNA-binding protein 43 79 44519 6.26 3 3 1 1 1 0.07 0.1
MAP4_MOUSE Microtubule-associated protein 4 79 117357 4.9 7 2 5 1 5 0.09 0.04
RAB9A_MOUSE Ras-related protein Rab-9A 79 22895 5.43 4 4 2 2 2 0.19 0.43
AGAL_MOUSE Alpha-galactosidase A 79 47611 5.44 6 4 5 3 5 0.21 0.3
ULA1_MOUSE NEDD8-activating enzyme E1 regulatory subunit 78 60236 5.34 4 3 3 2 3 0.15 0.15
EI2BA_MOUSE Translation initiation factor eIF-2B subunit alpha 78 33795 8.48 4 2 3 2 3 0.17 0.28
LPPRC_MOUSE Leucine-rich PPR motif-containing protein, mitochondrial 78 156516 6.42 10 6 7 4 7 0.12 0.11
SYK_MOUSE Lysine–tRNA ligase 78 67796 5.65 10 5 6 4 6 0.17 0.28
SWI5_MOUSE DNA repair protein SWI5 homolog 78 10254 4.67 1 1 1 1 1 0.19 0.49
FAM3C_MOUSE Protein FAM3C 77 24737 8.52 5 2 2 1 2 0.13 0.18
BLMH_MOUSE Bleomycin hydrolase 77 52477 6.04 8 3 6 2 6 0.26 0.17
TOIP1_MOUSE Torsin-1A-interacting protein 1 77 66740 6.58 2 2 2 2 2 0.04 0.13
NUDC_MOUSE Nuclear migration protein nudC 77 38334 5.17 2 1 2 1 2 0.06 0.11
GSHB_MOUSE Glutathione synthetase 77 52214 5.56 4 3 3 2 3 0.14 0.17
SPTC2_MOUSE Serine palmitoyltransferase 2 77 62941 8.43 8 4 4 1 4 0.14 0.07
CP20A_MOUSE Cytochrome P450 20A1 77 52116 6.48 4 2 3 1 3 0.13 0.08
USP9X_MOUSE Probable ubiquitin carboxyl-terminal hydrolase FAF-X 76 290526 5.57 19 6 10 3 10 0.08 0.04
ASPH_MOUSE Aspartyl/asparaginyl beta-hydroxylase 75 82991 4.97 9 4 8 4 8 0.17 0.22
ALDR_MOUSE Aldose reductase 76 35709 6.71 4 2 3 1 3 0.19 0.12
MGAT1_MOUSE Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase 76 51658 9.02 6 5 2 2 2 0.12 0.18
ATP5H_MOUSE ATP synthase subunit d, mitochondrial 76 18738 5.52 5 3 4 3 4 0.42 0.93
AT5F1_MOUSE ATP synthase F(0) complex subunit B1, mitochondrial 76 28930 9.11 5 1 5 1 5 0.34 0.15
IF2B_MOUSE Eukaryotic translation initiation factor 2 subunit 2 76 38068 5.61 6 3 4 2 4 0.19 0.24
HEAT3_MOUSE HEAT repeat-containing protein 3 75 74258 4.91 5 3 3 2 3 0.08 0.12
LCLT1_MOUSE Lysocardiolipin acyltransferase 1 75 44371 8.77 2 2 2 2 2 0.14 0.21
MCM6_MOUSE DNA replication licensing factor MCM6 75 92809 5.32 4 3 4 3 4 0.09 0.14
NDUA8_MOUSE NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 75 19979 8.76 3 2 2 1 2 0.23 0.23
POSTN_MOUSE Periostin 75 93085 7.27 11 4 6 2 6 0.18 0.09
ACDSB_MOUSE Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial 74 47843 8 4 1 3 1 3 0.13 0.09
EIF1_MOUSE Eukaryotic translation initiation factor 1 74 12739 6.89 2 1 2 1 2 0.33 0.38
IF1A_MOUSE Eukaryotic translation initiation factor 1A 73 16492 5.07 4 1 4 1 1 0.26 0.28
CHMP5_MOUSE Charged multivesicular body protein 5 73 24560 4.65 2 2 1 1 1 0.12 0.18
S10A4_MOUSE Protein S100-A4 73 11714 5.23 6 5 3 3 3 0.25 1.82
ITM2C_MOUSE Integral membrane protein 2C 73 30463 8.83 2 2 1 1 1 0.08 0.15
MEP50_MOUSE Methylosome protein 50 73 36919 5.09 2 2 1 1 1 0.09 0.12
NDUS8_MOUSE NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 73 24023 5.89 3 3 2 2 2 0.09 0.41
ZFPL1_MOUSE Zinc finger protein-like 1 73 34133 8.57 7 2 3 2 3 0.2 0.27
USMG5_MOUSE Upregulated during skeletal muscle growth protein 5 72 6377 9.84 2 2 1 1 1 0.26 0.87
VATL_MOUSE V-type proton ATPase 16 kDa proteolipid subunit 72 15798 9.1 1 1 1 1 1 0.2 0.3
SFRP1_MOUSE Secreted frizzled-related protein 1 72 35389 9.17 3 2 2 1 2 0.12 0.12
AAAS_MOUSE Aladin 72 59393 6.39 3 3 1 1 1 0.03 0.07
ABD12_MOUSE Monoacylglycerol lipase ABHD12 72 45241 8.9 3 1 2 1 2 0.07 0.1
SYIM_MOUSE Isoleucine–tRNA ligase, mitochondrial 72 112732 6.37 7 5 5 3 5 0.11 0.12
MAPK2_MOUSE MAP kinase-activated protein kinase 2 71 44022 8.77 7 2 5 2 5 0.19 0.21
BIEA_MOUSE Biliverdin reductase A 71 33504 6.53 6 5 4 4 4 0.25 0.64
AP3D1_MOUSE AP-3 complex subunit delta-1 71 134996 7.04 4 3 3 2 3 0.04 0.06
ALG5_MOUSE Dolichyl-phosphate beta-glucosyltransferase 71 36767 8.83 4 2 2 2 2 0.12 0.25
CD99_MOUSE CD99 antigen 71 16772 5.14 2 2 1 1 1 0.27 0.28
SYQ_MOUSE Glutamine–tRNA ligase 70 87621 6.93 8 2 5 2 5 0.12 0.1
TCEA1_MOUSE Transcription elongation factor A protein 1 70 33859 8.64 5 5 1 1 1 0.09 0.13
XDH_MOUSE Xanthine dehydrogenase/oxidase 70 146468 7.62 14 6 6 3 6 0.1 0.12
ANXA7_MOUSE Annexin A7 70 49893 5.91 5 2 5 2 5 0.16 0.18
IPYR2_MOUSE Inorganic pyrophosphatase 2, mitochondrial 70 38090 6.51 8 3 5 2 5 0.16 0.24
CY1_MOUSE Cytochrome c1, heme protein, mitochondrial 70 35305 9.24 2 1 2 1 2 0.12 0.12
NP1L4_MOUSE Nucleosome assembly protein 1-like 4 70 42653 4.56 6 3 5 3 4 0.24 0.34
NU133_MOUSE Nuclear pore complex protein Nup133 70 128539 5.06 5 2 5 2 5 0.09 0.07
SIAS_MOUSE Sialic acid synthase 70 39998 6.61 2 1 1 1 1 0.1 0.11
ETFA_MOUSE Electron transfer flavoprotein subunit alpha, mitochondrial 69 34988 8.62 10 5 5 3 5 0.33 0.43
GALM_MOUSE Aldose 1-epimerase 69 37775 6.26 3 1 2 1 2 0.12 0.12
ABCF1_MOUSE ATP-binding cassette sub-family F member 1 69 94887 6.15 3 2 2 1 2 0.06 0.05
T176B_MOUSE Transmembrane protein 176B 68 28349 8.03 2 1 2 1 2 0.22 0.16
ICAL_MOUSE Calpastatin 68 84871 5.37 6 3 4 2 4 0.1 0.1
THIM_MOUSE 3-Ketoacyl-CoA thiolase, mitochondrial 68 41803 8.33 3 1 3 1 3 0.13 0.1
CAPR1_MOUSE Caprin-1 67 78121 5.14 7 2 5 2 5 0.11 0.11
PTPA_MOUSE Serine/threonine-protein phosphatase 2A activator 67 36687 5.95 2 2 2 2 2 0.11 0.25
ATP5L_MOUSE ATP synthase subunit g, mitochondrial 67 11417 9.74 3 2 2 1 2 0.32 0.43
UBA6_MOUSE Ubiquitin-like modifier-activating enzyme 6 67 117891 5.75 7 1 6 1 6 0.11 0.04
VASP_MOUSE Vasodilator-stimulated phosphoprotein 67 39642 8.69 5 2 3 2 3 0.08 0.23
E41L2_MOUSE Band 4.1-like protein 2 67 109873 5.31 8 4 5 3 5 0.07 0.12
GLRX3_MOUSE Glutaredoxin-3 67 37754 5.42 16 7 8 6 8 0.46 0.94
TRXR1_MOUSE Thioredoxin reductase 1, cytoplasmic 66 67042 7.42 12 4 6 2 6 0.19 0.13
IASPP_MOUSE RelA-associated inhibitor 66 88921 6.39 3 1 3 1 3 0.1 0.05
NUP85_MOUSE Nuclear pore complex protein Nup85 66 74728 5.37 6 3 4 1 4 0.09 0.06
DDX18_MOUSE ATP-dependent RNA helicase DDX18 66 74134 9.54 6 4 3 2 3 0.07 0.12
NEUL_MOUSE Neurolysin, mitochondrial 66 80378 6.01 10 4 7 2 7 0.18 0.11
MLEC_MOUSE Malectin 66 32322 5.73 8 3 6 2 6 0.37 0.47
GPC4_MOUSE Glypican-4 65 62546 5.96 3 1 3 1 3 0.13 0.07
KIME_MOUSE Mevalonate kinase 65 41851 6.22 4 3 2 1 2 0.14 0.1
EIF3L_MOUSE Eukaryotic translation initiation factor 3 subunit L 65 66570 6.01 5 3 4 2 4 0.13 0.13
G3BP1_MOUSE Ras GTPase-activating protein-binding protein 1 65 51797 5.41 10 3 9 3 9 0.31 0.27
CTNB1_MOUSE Catenin beta-1 64 85416 5.53 10 3 5 2 5 0.13 0.1
ACADL_MOUSE Long-chain specific acyl-CoA dehydrogenase, mitochondrial 64 47877 8.53 10 3 5 3 3 0.17 0.3
HXK1_MOUSE Hexokinase-1 64 108234 6.37 7 3 6 3 6 0.09 0.12
TF_MOUSE Tissue factor 64 32914 9.4 2 2 1 1 1 0.09 0.13
MYEF2_MOUSE Myelin expression factor 2 64 63254 8.96 3 1 3 1 3 0.05 0.07
ANM5_MOUSE Protein arginine N-methyltransferase 5 64 72634 5.99 16 3 7 1 7 0.25 0.12
MED11_MOUSE Mediator of RNA polymerase II transcription subunit 11 63 13123 5.71 3 3 1 1 1 0.21 0.86
HEAT6_MOUSE HEAT repeat-containing protein 6 63 128840 6.88 5 3 3 1 3 0.06 0.03
NAMPT_MOUSE Nicotinamide phosphoribosyltransferase 63 55413 6.69 3 2 2 2 2 0.09 0.16
MYO9B_MOUSE Unconventional myosin-Ixb 63 238685 8.82 3 1 3 1 3 0.03 0.02
AL1L2_MOUSE Mitochondrial 10-formyltetrahydrofolate dehydrogenase 63 101526 5.93 5 1 4 1 4 0.08 0.04
HSBP1_MOUSE Heat shock factor-binding protein 1 63 8605 4.11 2 1 1 1 1 0.25 0.59
MYG1_MOUSE UPF0160 protein MYG1, mitochondrial 63 42696 6.54 1 1 1 1 1 0.04 0.1
RBM3_MOUSE RNA-binding protein 3 62 16595 6.84 11 4 4 2 4 0.46 0.64
SLIT3_MOUSE Slit homolog 3 protein 62 167617 7.95 13 2 7 2 7 0.11 0.05
PPM1B_MOUSE Protein phosphatase 1B 62 42768 5.04 3 1 2 1 2 0.11 0.1
DPEP1_MOUSE Dipeptidase 1 62 45693 5.9 4 1 3 1 3 0.23 0.1
F10A1_MOUSE Hsc70-interacting protein 62 41630 5.19 6 3 3 2 3 0.12 0.22
MCFD2_MOUSE Multiple coagulation factor deficiency protein 2 homolog 62 16158 4.55 1 1 1 1 1 0.17 0.29
RM12_MOUSE 39S ribosomal protein L12, mitochondrial 62 21695 9.34 8 2 3 1 3 0.2 0.46
FDFT_MOUSE Squalene synthase 61 48123 5.91 5 2 2 2 2 0.06 0.19
LGUL_MOUSE Lactoylglutathione lyase 61 20796 5.24 8 3 4 1 4 0.33 0.22
CDK4_MOUSE Cyclin-dependent kinase 4 54 33729 6.16 6 2 5 2 5 0.31 0.28
CDC37_MOUSE Hsp90 co-chaperone Cdc37 61 44565 5.24 4 2 3 2 2 0.13 0.21
CDK1_MOUSE Cyclin-dependent kinase 1 61 34085 8.39 10 6 5 3 5 0.27 0.44
LETM1_MOUSE Mitochondrial proton/calcium exchanger protein 61 82937 6.16 7 1 6 1 6 0.15 0.05
PGM1_MOUSE Phosphoglucomutase-1 60 61380 6.14 6 3 6 3 6 0.29 0.23
LAMP2_MOUSE Lysosome-associated membrane glycoprotein 2 60 45652 7.05 12 4 8 3 8 0.25 0.31
PKD2_MOUSE Polycystin-2 60 108914 5.47 4 1 4 1 4 0.08 0.04
UCHL1_MOUSE Ubiquitin carboxyl-terminal hydrolase isozyme L1 60 24822 5.14 7 4 5 3 5 0.38 0.65
COPD_MOUSE Coatomer subunit delta 60 57193 5.89 18 4 12 3 12 0.34 0.24
IRGM1_MOUSE Immunity-related GTPase family M protein 1 60 46522 8.56 4 3 2 1 2 0.13 0.09
AKA12_MOUSE A-kinase anchor protein 12 60 180586 4.39 11 2 5 2 5 0.05 0.05
MP2K4_MOUSE Dual specificity mitogen-activated protein kinase 4 60 44085 8.28 5 2 5 2 5 0.27 0.21
NCLN_MOUSE Nicalin 59 62868 6.03 3 2 2 2 2 0.06 0.14
LMF2_MOUSE Lipase maturation factor 2 58 79947 9.99 4 3 2 2 2 0.06 0.11
FHL1_MOUSE Four and a half LIM domains protein 1 59 31867 8.76 6 3 3 2 3 0.17 0.3
ARHG7_MOUSE Rho guanine nucleotide exchange factor 7 59 96995 6.35 2 1 2 1 2 0.04 0.04
PP14B_MOUSE Protein phosphatase 1 regulatory subunit 14B 59 15947 4.74 10 6 2 2 2 0.29 0.67
MANF_MOUSE Mesencephalic astrocyte-derived neurotrophic factor 59 20361 8.34 12 4 3 3 3 0.21 0.84
ACOT2_MOUSE Acyl-coenzyme A thioesterase 2, mitochondrial 59 49626 6.88 4 3 2 2 2 0.08 0.18
S23IP_MOUSE SEC23-interacting protein 59 110711 5.63 11 6 6 3 6 0.14 0.12
ERP29_MOUSE Endoplasmic reticulum resident protein 29 58 28805 5.9 7 3 2 2 2 0.14 0.33
CO6A1_MOUSE Collagen alpha-1(VI) chain 58 108422 5.2 5 2 4 1 4 0.1 0.04
DBNL_MOUSE Drebrin-like protein 58 48670 4.9 4 2 2 1 2 0.1 0.09
SCPDL_MOUSE Saccharopine dehydrogenase-like oxidoreductase 58 47099 8.86 6 3 3 1 3 0.2 0.09
PP1R7_MOUSE Protein phosphatase 1 regulatory subunit 7 58 41266 4.85 5 3 2 1 2 0.14 0.22
MGST1_MOUSE Microsomal glutathione S-transferase 1 58 17540 9.67 2 1 1 1 1 0.21 0.26
MON2_MOUSE Protein MON2 homolog 58 188958 5.77 6 2 5 2 5 0.08 0.05
PARK7_MOUSE Protein/nucleic acid deglycase DJ-1 57 20008 6.32 3 2 3 2 3 0.27 0.51
WASC4_MOUSE WASH complex subunit 4 57 136283 6.99 5 2 5 2 5 0.09 0.06
AKAP1_MOUSE A-kinase anchor protein 1, mitochondrial 57 92137 4.91 2 1 2 1 2 0.03 0.05
MALD1_MOUSE MARVEL domain-containing protein 1 57 19074 9.77 5 3 2 1 2 0.21 0.24
SPEE_MOUSE Spermidine synthase 57 33973 5.31 7 3 5 3 5 0.3 0.44
RFIP5_MOUSE Rab11 family-interacting protein 5 57 69510 9.17 5 3 2 1 2 0.04 0.06
EXOC1_MOUSE Exocyst complex component 1 57 101825 6.09 6 3 5 2 5 0.13 0.09
DOCK7_MOUSE Dedicator of cytokinesis protein 7 56 241286 6.25 15 2 8 2 8 0.08 0.04
NDUA4_MOUSE Cytochrome c oxidase subunit NDUFA4 56 9321 9.52 4 2 2 1 2 0.46 0.54
TGFI1_MOUSE Transforming growth factor beta-1-induced transcript 1 protein 56 50068 6.28 8 4 3 2 3 0.18 0.18
HUWE1_MOUSE E3 ubiquitin-protein ligase HUWE1 56 482332 5.1 10 2 9 1 9 0.04 0.01
LBR_MOUSE Lamin-B receptor 56 71395 9.43 4 1 4 1 4 0.09 0.06
MARC2_MOUSE Mitochondrial amidoxime reducing component 2 56 38170 8.95 4 2 3 2 3 0.18 0.24
CMC1_MOUSE Calcium-binding mitochondrial carrier protein Aralar1 56 74523 8.43 4 3 2 2 2 0.05 0.12
BAX_MOUSE Apoptosis regulator BAX 56 21381 4.86 1 1 1 1 1 0.07 0.21
BASP1_MOUSE Brain acid soluble protein 1 56 22074 4.5 14 2 1 1 1 0.14 0.21
HINT1_MOUSE Histidine triad nucleotide-binding protein 1 56 13768 6.36 4 1 4 1 4 0.6 0.35
SCYL1_MOUSE N-terminal kinase-like protein 56 89104 6.03 2 1 2 1 2 0.06 0.05
QCR2_MOUSE Cytochrome b-c1 complex subunit 2, mitochondrial 55 48205 9.26 2 1 2 1 2 0.08 0.09
TMF1_MOUSE TATA element modulatory factor 55 121729 4.83 4 1 4 1 4 0.07 0.03
RENT1_MOUSE Regulator of nonsense transcripts 1 55 123889 6.18 7 2 6 2 6 0.13 0.07
IKIP_MOUSE Inhibitor of nuclear factor kappa-B kinase-interacting protein 55 42505 5.03 6 4 4 3 4 0.19 0.34
HPRT_MOUSE Hypoxanthine-guanine phosphoribosyltransferase 53 24555 6.21 6 4 3 3 2 0.32 0.66
ISC2A_MOUSE Isochorismatase domain-containing protein 2A 55 22403 8.25 1 1 1 1 1 0.13 0.2
NU4M_MOUSE NADH-ubiquinone oxidoreductase chain 4 55 51847 9.42 3 1 2 1 2 0.04 0.08
CTL2_MOUSE Choline transporter-like protein 2 55 80057 9.06 5 4 1 1 1 0.02 0.05
JIP4_MOUSE C-Jun-amino-terminal kinase-interacting protein 4 54 146129 5.05 8 2 6 2 6 0.09 0.06
5NT3B_MOUSE 7-Methylguanosine phosphate-specific 5 -nucleotidase 54 34403 5.82 1 1 1 1 1 0.07 0.13
LAP2A_MOUSE Lamina-associated polypeptide 2, isoforms alpha/zeta 54 75122 8.29 4 1 2 1 2 0.05 0.06
EM55_MOUSE 55 kDa erythrocyte membrane protein 54 52194 6.72 6 3 4 3 4 0.16 0.27
KAP0_MOUSE cAMP-dependent protein kinase type I-alpha regulatory subunit 54 43158 5.27 5 2 3 1 3 0.15 0.1
GDIR2_MOUSE Rho GDP-dissociation inhibitor 2 54 22836 4.97 7 4 4 3 4 0.26 0.72
NDUS2_MOUSE NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 54 52592 6.52 4 1 3 1 3 0.14 0.08
SYHC_MOUSE Histidine–tRNA ligase, cytoplasmic 53 57396 5.79 4 3 4 3 4 0.17 0.24
IVD_MOUSE Isovaleryl-CoA dehydrogenase, mitochondrial 54 46296 8.53 10 2 4 2 4 0.26 0.2
DHRS1_MOUSE Dehydrogenase/reductase SDR family member 1 54 33983 8.66 1 1 1 1 1 0.06 0.13
SRP68_MOUSE Signal recognition particle subunit SRP68 53 70530 8.77 5 1 5 1 5 0.13 0.06
PREP_MOUSE Presequence protease, mitochondrial 53 117297 6.76 6 4 6 4 6 0.13 0.15
GUAA_MOUSE GMP synthase [glutamine-hydrolyzing] 53 76675 6.29 3 2 2 1 2 0.09 0.06
NT5C_MOUSE 5 (3 )-Deoxyribonucleotidase, cytosolic type 53 23062 5.31 2 1 2 1 2 0.2 0.2
DNMT1_MOUSE DNA (cytosine-5)-methyltransferase 1 53 183074 7.92 6 1 6 1 6 0.08 0.02
GALK1_MOUSE Galactokinase 53 42268 5.17 2 1 2 1 2 0.07 0.1
PSD12_MOUSE 26S proteasome non-ATPase regulatory subunit 12 53 52861 6.66 11 3 8 3 8 0.25 0.27
GLMP_MOUSE Glycosylated lysosomal membrane protein 52 43776 5.73 4 1 3 1 3 0.18 0.1
UD17C_MOUSE UDP-glucuronosyltransferase 1-7C 52 59719 8.64 6 3 5 3 5 0.18 0.23
DHPR_MOUSE Dihydropteridine reductase 52 25554 7.67 3 1 2 1 2 0.19 0.18
NAA25_MOUSE N-Alpha-acetyltransferase 25, NatB auxiliary subunit 52 111637 6.1 2 1 2 1 2 0.04 0.04
LDAH_MOUSE Lipid droplet-associated hydrolase 52 37349 8.5 4 2 3 1 3 0.22 0.12
TR10B_MOUSE Tumor necrosis factor receptor superfamily member 10B 52 42138 6.75 1 1 1 1 1 0.06 0.1
BAG2_MOUSE BAG family molecular chaperone regulator 2 52 23459 6.01 7 1 5 1 5 0.38 0.19
DNPEP_MOUSE Aspartyl aminopeptidase 52 52174 6.82 10 4 3 1 3 0.19 0.17
ODO2_MOUSE Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial 52 48963 9.11 4 2 2 1 2 0.07 0.09
TBCB_MOUSE Tubulin-folding cofactor B 52 27368 5.14 2 2 1 1 1 0.08 0.16
PNKP_MOUSE Bifunctional polynucleotide phosphatase/kinase 51 57188 8.03 1 1 1 1 1 0.04 0.08
ASAH1_MOUSE Acid ceramidase 51 44641 8.68 10 4 6 3 6 0.24 0.32
VATE1_MOUSE V-type proton ATPase subunit E 1 51 26141 8.44 4 2 3 1 3 0.3 0.17
ITPA_MOUSE Inosine triphosphate pyrophosphatase 51 21883 5.6 4 1 2 1 2 0.15 0.21
MCM2_MOUSE DNA replication licensing factor MCM2 51 102013 5.49 6 2 4 1 4 0.09 0.04
B2MG_MOUSE Beta-2-microglobulin 50 13770 8.55 2 1 2 1 2 0.31 0.35
MRCKB_MOUSE Serine/threonine-protein kinase MRCK beta 50 194630 6.05 8 5 5 2 5 0.06 0.04
TCOF_MOUSE Treacle protein 50 134921 9.35 3 2 2 1 2 0.04 0.03
ACOT9_MOUSE Acyl-coenzyme A thioesterase 9, mitochondrial 50 50528 8.74 8 3 5 2 5 0.23 0.18
RRP1_MOUSE Ribosomal RNA processing protein 1 homolog A 50 54743 5.04 1 1 1 1 1 0.05 0.08
CHRD1_MOUSE Cysteine and histidine-rich domain-containing protein 1 50 37327 8.13 4 1 3 1 3 0.18 0.12
HMGCL_MOUSE Hydroxymethylglutaryl-CoA lyase, mitochondrial 50 34217 8.7 5 2 4 2 4 0.18 0.27
ANFY1_MOUSE Rabankyrin-5 49 128571 5.58 6 3 6 3 6 0.11 0.1
MOGS_MOUSE Mannosyl-oligosaccharide glucosidase 49 91774 9.06 7 4 4 3 4 0.1 0.15
SAMH1_MOUSE Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 49 72604 8.17 7 3 6 3 6 0.18 0.19
MPRIP_MOUSE Myosin phosphatase Rho-interacting protein 49 116337 5.9 6 1 4 1 4 0.07 0.04
G6PD1_MOUSE Glucose-6-phosphate 1-dehydrogenase X 49 59225 6.06 17 4 9 2 9 0.32 0.15
ATP5I_MOUSE ATP synthase subunit e, mitochondrial 49 8230 9.34 2 1 1 1 1 0.18 0.63
RL14_MOUSE 60S ribosomal protein L14 49 23549 11.03 4 1 4 1 4 0.23 0.19
FABP4_MOUSE Fatty acid-binding protein, adipocyte 49 14641 8.53 2 1 2 1 2 0.27 0.32
MCM7_MOUSE DNA replication licensing factor MCM7 49 81160 5.98 6 2 6 2 6 0.16 0.11
S2611_MOUSE Sodium-independent sulfate anion transporter 49 64068 7.56 4 3 2 1 2 0.08 0.07
UBQL1_MOUSE Ubiquilin-1 49 61937 4.86 10 4 4 2 4 0.13 0.14
GSH0_MOUSE Glutamate–cysteine ligase regulatory subunit 49 30516 5.35 2 1 2 1 2 0.17 0.15
PDK3_MOUSE [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 49 47893 8.89 1 1 1 1 1 0.04 0.09
P3H3_MOUSE Prolyl 3-hydroxylase 3 48 81650 6.21 7 2 5 1 5 0.14 0.05
ARP10_MOUSE Actin-related protein 10 48 46178 7.54 4 2 4 2 4 0.2 0.2
ARL2_MOUSE ADP-ribosylation factor-like protein 2 48 20851 5.67 4 2 1 1 1 0.14 0.22
LAMA5_MOUSE Laminin subunit alpha-5 48 403792 6.28 6 1 3 1 3 0.02 0.01
IFI5B_MOUSE Interferon-activable protein 205-B 48 46948 8.2 11 2 8 2 8 0.27 0.19
NXN_MOUSE Nucleoredoxin 48 48314 4.84 2 1 2 1 2 0.12 0.09
TTC27_MOUSE Tetratricopeptide repeat protein 27 47 96369 5.56 9 3 4 2 4 0.11 0.09
GPAA1_MOUSE Glycosylphosphatidylinositol anchor attachment 1 protein 47 67905 8.61 2 1 2 1 2 0.08 0.06
CP062_MOUSE UPF0505 protein C16orf62 homolog 47 109007 6.97 7 1 5 1 5 0.08 0.04
CNOT1_MOUSE CCR4-NOT transcription complex subunit 1 47 266637 6.65 8 2 8 2 8 0.07 0.03
NDUS3_MOUSE NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 47 30131 6.67 4 1 3 1 3 0.18 0.15
CGNL1_MOUSE Cingulin-like protein 1 47 148140 5.6 5 1 5 1 5 0.06 0.03
MCES_MOUSE mRNA cap guanine-N7 methyltransferase 47 53258 6.12 4 2 3 1 3 0.09 0.08
EXOC7_MOUSE Exocyst complex component 7 47 79910 6.51 6 2 4 1 4 0.14 0.05
GOGA3_MOUSE Golgin subfamily A member 3 47 167118 5.29 7 1 7 1 7 0.1 0.03
IR3IP_MOUSE Immediate early response 3-interacting protein 1 47 9011 7.96 2 1 2 1 2 0.32 0.56
CIP4_MOUSE Cdc42-interacting protein 4 47 68447 5.66 1 1 1 1 1 0.02 0.06
GALT2_MOUSE Polypeptide N-acetylgalactosaminyltransferase 2 46 64473 8.8 9 1 6 1 6 0.17 0.07
CD9_MOUSE CD9 antigen 46 25241 6.88 5 4 2 1 2 0.26 0.18
NOP58_MOUSE Nucleolar protein 58 46 60305 8.53 4 1 3 1 3 0.11 0.07
NIPS2_MOUSE Protein NipSnap homolog 2 46 32912 9.31 4 2 2 2 2 0.15 0.29
AMPB_MOUSE Aminopeptidase B 45 72370 5.22 7 3 6 3 6 0.22 0.19
NB5R1_MOUSE NADH-cytochrome b5 reductase 1 45 34113 8.97 4 1 3 1 3 0.15 0.13
VPP2_MOUSE V-type proton ATPase 116 kDa subunit a isoform 2 45 98081 6.2 3 1 2 1 2 0.05 0.04
IMPCT_MOUSE Protein IMPACT 45 36253 4.97 9 2 4 2 4 0.24 0.26
MARE3_MOUSE Microtubule-associated protein RP/EB family member 3 45 31946 5.33 2 1 2 1 2 0.17 0.14
TMM43_MOUSE Transmembrane protein 43 45 44755 6.85 3 2 3 2 3 0.14 0.2
FA98B_MOUSE Protein FAM98B 45 45321 8.77 4 1 3 1 3 0.19 0.1
ERP44_MOUSE Endoplasmic reticulum resident protein 44 44 46823 5.09 2 1 2 1 2 0.1 0.09
TSP2_MOUSE Thrombospondin-2 44 129798 4.61 9 2 6 2 5 0.1 0.07
HEM2_MOUSE Delta-aminolevulinic acid dehydratase 44 36000 6.32 11 7 3 1 3 0.2 0.12
UROK_MOUSE Urokinase-type plasminogen activator 44 48236 8.53 5 1 3 1 3 0.17 0.09
IF4G2_MOUSE Eukaryotic translation initiation factor 4 gamma 2 44 102041 6.7 10 5 7 3 7 0.14 0.13
RSU1_MOUSE Ras suppressor protein 1 44 31531 8.86 10 2 5 1 5 0.39 0.14
ITB5_MOUSE Integrin beta-5 44 87851 5.81 8 3 8 3 8 0.22 0.15
SEP10_MOUSE Septin-10 44 52388 6.17 8 2 5 1 5 0.15 0.08
EMC1_MOUSE ER membrane protein complex subunit 1 44 111535 7 11 3 7 3 7 0.15 0.12
A16L1_MOUSE Autophagy-related protein 16-1 43 68130 5.96 6 1 2 1 2 0.06 0.06
MINP1_MOUSE Multiple inositol polyphosphate phosphatase 1 43 54503 7.21 3 2 2 1 2 0.09 0.08
MTAP_MOUSE S-Methyl-5 -thioadenosine phosphorylase 43 31042 6.71 6 3 3 2 3 0.22 0.31
EMAL2_MOUSE Echinoderm microtubule-associated protein-like 2 43 70689 5.83 5 2 2 1 2 0.07 0.06
ACADV_MOUSE Very-long-chain-specific acyl-CoA dehydrogenase, mitochondrial 43 70831 8.91 9 1 6 1 6 0.19 0.06
AOFB_MOUSE Amine oxidase [flavin-containing] B 43 58520 8.52 7 2 5 2 5 0.16 0.15
NRADD_MOUSE Death domain-containing membrane protein NRADD 43 24711 4.89 3 3 1 1 1 0.14 0.4
DHSD_MOUSE Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial 43 17003 9.3 1 1 1 1 1 0.16 0.27
CSN9_MOUSE COP9 signalosome complex subunit 9 43 6193 3.6 1 1 1 1 1 0.35 0.89
VP13C_MOUSE Vacuolar protein sorting-associated protein 13C 43 419824 6.37 8 1 8 1 8 0.05 0.01
EMAL1_MOUSE Echinoderm microtubule-associated protein-like 1 43 89624 6.56 10 2 8 2 8 0.21 0.1
TIP_MOUSE T cell immunomodulatory protein 42 67422 5.4 6 1 2 1 2 0.09 0.06
CLU_MOUSE Clustered mitochondria protein homolog 42 147975 5.69 2 2 2 2 2 0.03 0.06
PSME1_MOUSE Proteasome activator complex subunit 1 40 28655 5.73 5 3 4 3 4 0.26 0.54
MFGM_MOUSE Lactadherin 42 51208 6.1 8 3 6 3 6 0.19 0.28
E41L3_MOUSE Band 4.1-like protein 3 42 103274 5.2 1 1 1 1 1 0.01 0.04
LMAN2_MOUSE Vesicular integral-membrane protein VIP36 42 40404 6.46 6 2 5 2 5 0.23 0.23
PPM1F_MOUSE Protein phosphatase 1F 42 49580 5.16 6 3 5 3 5 0.28 0.29
SERC3_MOUSE Serine incorporator 3 42 52588 6.95 1 1 1 1 1 0.06 0.08
ARHG1_MOUSE Rho guanine nucleotide exchange factor 1 42 102741 5.43 6 2 6 2 6 0.11 0.08
RS27A_MOUSE Ubiquitin-40S ribosomal protein S27a 34 17939 9.68 7 2 2 2 2 0.22 0.58
MANEA_MOUSE Glycoprotein endo-alpha-1,2-mannosidase 42 53149 8.66 1 1 1 1 1 0.03 0.08
MYO1B_MOUSE Unconventional myosin-Ib 41 128483 9.32 3 1 2 1 2 0.04 0.03
PTCD3_MOUSE Pentatricopeptide repeat domain-containing protein 3, mitochondrial 41 77747 5.61 4 2 3 1 3 0.08 0.06
COG2_MOUSE Conserved oligomeric Golgi complex subunit 2 41 81988 5.84 2 1 2 1 2 0.09 0.05
KTN1_MOUSE Kinectin 41 152498 5.67 7 2 7 2 7 0.1 0.06
ARXS1_MOUSE Adipocyte-related X-chromosome expressed sequence 1 41 20134 9.6 2 1 2 1 2 0.14 0.23
RAB23_MOUSE Ras-related protein Rab-23 41 26662 6.36 4 1 4 1 4 0.41 0.17
SMRC1_MOUSE SWI/SNF complex subunit SMARCC1 41 122813 5.5 5 1 5 1 4 0.08 0.03
HGNAT_MOUSE Heparan-alpha-glucosaminide N-acetyltransferase 41 72458 8.58 2 2 1 1 1 0.05 0.06
GGCT_MOUSE Gamma-glutamylcyclotransferase 41 21152 5.52 3 1 3 1 3 0.31 0.21
PLPP1_MOUSE Phospholipid phosphatase 1 41 31871 6.54 6 3 3 2 3 0.16 0.3
RFOX2_MOUSE RNA binding protein fox-1 homolog 2 40 47301 6.1 3 1 3 1 3 0.1 0.09
DPP9_MOUSE Dipeptidyl peptidase 9 40 97939 6.18 3 1 3 1 3 0.03 0.04
CD63_MOUSE CD63 antigen 40 25749 6.69 3 2 1 1 1 0.05 0.17
ARFG1_MOUSE ADP-ribosylation factor GTPase-activating protein 1 40 45260 5.39 2 1 2 1 2 0.11 0.1
NOP16_MOUSE Nucleolar protein 16 40 21126 9.91 1 1 1 1 1 0.1 0.22
SNRPA_MOUSE U1 small nuclear ribonucleoprotein A 40 31814 9.81 3 1 3 1 3 0.18 0.14
KIF1C_MOUSE Kinesin-like protein KIF1C 40 122358 6.62 6 1 5 1 5 0.1 0.03
LRC40_MOUSE Leucine-rich repeat-containing protein 40 40 68033 6.43 3 1 3 1 3 0.1 0.06
MAOM_MOUSE NAD-dependent malic enzyme, mitochondrial 40 65757 7.53 2 2 2 2 2 0.08 0.14
LAMB1_MOUSE Laminin subunit beta-1 40 196961 4.82 13 2 6 1 6 0.08 0.02
GTR1_MOUSE Solute carrier family 2, facilitated glucose transporter member 1 40 53949 9.05 5 3 4 2 4 0.13 0.17
CKAP5_MOUSE Cytoskeleton-associated protein 5 40 225492 8.17 11 2 9 2 9 0.08 0.04
LYAR_MOUSE Cell growth-regulating nucleolar protein 40 43708 9.52 4 1 3 1 3 0.1 0.1
SAAL1_MOUSE Protein SAAL1 40 52735 4.4 4 1 4 1 4 0.2 0.08
WDR12_MOUSE Ribosome biogenesis protein WDR12 40 47317 5.36 2 1 1 1 1 0.08 0.09
TBC15_MOUSE TBC1 domain family member 15 39 76478 5.15 2 2 1 1 1 0.04 0.06
PGLT1_MOUSE Protein O-glucosyltransferase 1 39 46350 9.04 2 2 2 2 2 0.11 0.2
ACOD2_MOUSE Acyl-CoA desaturase 2 39 40890 9.14 2 1 2 1 2 0.12 0.11
ARHG2_MOUSE Rho guanine nucleotide exchange factor 2 39 111905 6.89 3 2 2 1 2 0.06 0.04
NFKB2_MOUSE Nuclear factor NF-kappa-B p100 subunit 39 96772 5.93 4 3 2 2 2 0.06 0.09
NU188_MOUSE Nucleoporin NUP188 homolog 39 196570 6.56 5 1 4 1 4 0.05 0.02
MCA3_MOUSE Eukaryotic translation elongation factor 1 epsilon-1 39 19846 8.6 4 2 3 1 3 0.33 0.23
STING_MOUSE Stimulator of interferon genes protein 39 42802 7.12 6 3 4 2 4 0.23 0.21
5NT3A_MOUSE Cytosolic 5 -nucleotidase 3A 39 37228 6.21 2 1 2 1 2 0.15 0.12
NDUV3_MOUSE NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 39 11806 9.34 3 2 2 1 2 0.32 0.41
MTX1_MOUSE Metaxin-1 39 35601 5.82 2 2 1 1 1 0.04 0.12
EMC3_MOUSE ER membrane protein complex subunit 3 39 29960 6.33 4 3 2 1 2 0.16 0.15
TULP3_MOUSE Tubby-related protein 3 38 51199 5.88 3 1 2 1 2 0.12 0.08
SEC63_MOUSE Translocation protein SEC63 homolog 38 87815 5.28 8 3 5 3 5 0.09 0.15
TFAM_MOUSE Transcription factor A, mitochondrial 38 27970 9.71 1 1 1 1 1 0.06 0.16
TMX4_MOUSE Thioredoxin-related transmembrane protein 4 38 37108 4.3 2 1 1 1 1 0.05 0.12
SP16H_MOUSE FACT complex subunit SPT16 38 119749 5.5 7 3 4 2 4 0.08 0.07
ACADS_MOUSE Short-chain specific acyl-CoA dehydrogenase, mitochondrial 38 44861 8.68 2 2 1 1 1 0.08 0.1
HEXB_MOUSE Beta-hexosaminidase subunit beta 38 61077 8.29 4 2 2 1 2 0.11 0.07
GBP2_MOUSE Guanylate-binding protein 2 38 66697 5.56 2 2 1 1 1 0.04 0.06
SK2L2_MOUSE Superkiller viralicidic activity 2-like 2 37 117561 6.01 10 2 8 1 8 0.16 0.04
PFKAP_MOUSE ATP-dependent 6-phosphofructokinase, platelet type 37 85400 6.73 9 1 8 1 8 0.18 0.05
T2FB_MOUSE General transcription factor IIF subunit 2 37 28364 9.23 3 1 2 1 2 0.11 0.16
SAM50_MOUSE Sorting and assembly machinery component 50 homolog 37 51831 6.34 3 1 3 1 3 0.12 0.08
XRCC6_MOUSE X-ray repair cross-complementing protein 6 37 69441 6.35 1 1 1 1 1 0.03 0.06
KBL_MOUSE 2-Amino-3-ketobutyrate coenzyme A ligase, mitochondrial 37 44902 6.92 1 1 1 1 1 0.06 0.1
PRI2_MOUSE DNA primase large subunit 37 58372 8.47 3 1 3 1 3 0.13 0.07
TGM2_MOUSE Protein-glutamine gamma-glutamyltransferase 2 37 77012 4.98 2 2 2 2 2 0.07 0.11
SPART_MOUSE Spartin 37 72610 5.64 4 1 3 1 3 0.12 0.06
SRRM1_MOUSE Serine/arginine repetitive matrix protein 1 37 106798 11.87 4 1 2 1 2 0.04 0.04
CSPG4_MOUSE Chondroitin sulfate proteoglycan 4 37 252153 5.23 8 2 7 2 7 0.07 0.03
DHX29_MOUSE ATP-dependent RNA helicase DHX29 36 153879 8.13 3 1 3 1 3 0.03 0.03
DECR_MOUSE 2,4-Dienoyl-CoA reductase, mitochondrial 36 36191 9.1 6 2 5 1 5 0.22 0.12
CHKB_MOUSE Choline/ethanolamine kinase 36 45097 5.3 3 1 2 1 2 0.12 0.1
RLA1_MOUSE 60S acidic ribosomal protein P1 36 11468 4.28 2 2 1 1 1 0.14 0.43
MBD3_MOUSE Methyl-CpG-binding domain protein 3 36 32148 5.64 3 1 2 1 2 0.11 0.14
IF6_MOUSE Eukaryotic translation initiation factor 6 36 26494 4.63 2 1 2 1 2 0.26 0.17
NISCH_MOUSE Nischarin 36 174903 5.05 3 2 3 2 3 0.04 0.05
CD44_MOUSE CD44 antigen 36 85565 4.82 4 3 2 2 2 0.05 0.1
NPM3_MOUSE Nucleoplasmin-3 36 19011 4.71 1 1 1 1 1 0.19 0.24
SNX2_MOUSE Sorting nexin-2 35 58435 5.04 2 1 2 1 2 0.1 0.07
MRP1_MOUSE Multidrug resistance-associated protein 1 35 171075 7.03 5 1 5 1 5 0.07 0.02
SERB_MOUSE Phosphoserine phosphatase 35 25080 5.81 4 2 3 2 3 0.24 0.39
SMYD5_MOUSE SET and MYND domain-containing protein 5 35 47065 5.09 2 1 1 1 1 0.06 0.09
PGFRB_MOUSE Platelet-derived growth factor receptor beta 35 122728 4.99 8 2 6 2 6 0.09 0.07
APAF_MOUSE Apoptotic protease-activating factor 1 35 140913 5.98 6 1 3 1 3 0.04 0.03
PLS3_MOUSE Phospholipid scramblase 3 35 31782 5.97 6 2 3 2 3 0.11 0.3
NMRL1_MOUSE NmrA-like family domain-containing protein 1 35 34355 6.37 3 1 2 1 2 0.15 0.13
EHD2_MOUSE EH domain-containing protein 2 35 61136 6.08 10 3 6 3 6 0.21 0.23
CRKL_MOUSE Crk-like protein 34 33809 6.26 9 2 4 1 4 0.23 0.13
EI2BB_MOUSE Translation initiation factor eIF-2B subunit beta 34 38873 5.82 4 2 3 1 3 0.22 0.11
BLVRB_MOUSE Flavin reductase (NADPH) 34 22183 6.49 7 1 4 1 4 0.38 0.2
SRSF6_MOUSE Serine/arginine-rich splicing factor 6 34 39002 11.46 2 1 1 1 1 0.07 0.11
TRI47_MOUSE Tripartite motif-containing protein 47 34 69868 6 2 2 1 1 1 0.05 0.06
ICLN_MOUSE Methylosome subunit pICln 34 26005 3.98 2 1 2 1 2 0.15 0.17
GNS_MOUSE N-Acetylglucosamine-6-sulfatase 34 61136 8.52 16 2 9 2 9 0.35 0.15
PLBL2_MOUSE Putative phospholipase B-like 2 34 66247 5.77 5 1 4 1 4 0.12 0.07
TBCA_MOUSE Tubulin-specific chaperone A 34 12750 5.24 3 1 2 1 2 0.37 0.38
SGPL1_MOUSE Sphingosine-1-phosphate lyase 1 34 63636 9.2 6 1 5 1 5 0.11 0.07
T126A_MOUSE Transmembrane protein 126A 34 21526 9.45 2 1 2 1 2 0.17 0.21
DHR11_MOUSE Dehydrogenase/reductase SDR family member 11 34 28256 5.91 3 2 2 1 2 0.17 0.16
KTAP2_MOUSE Keratinocyte-associated protein 2 34 14665 9.67 3 1 1 1 1 0.2 0.32
LAMC1_MOUSE Laminin subunit gamma-1 33 177185 5.08 3 1 3 1 3 0.04 0.02
3HIDH_MOUSE 3-Hydroxyisobutyrate dehydrogenase, mitochondrial 33 35417 8.37 3 1 2 1 2 0.19 0.12
BGAL_MOUSE Beta-galactosidase 33 73074 7.15 2 1 2 1 2 0.06 0.06
FKBP8_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP8 33 43501 5.08 2 1 2 1 2 0.11 0.1
CASP3_MOUSE Caspase-3 33 31454 6.45 4 1 3 1 3 0.24 0.14
RT33_MOUSE 28S ribosomal protein S33, mitochondrial 33 12452 10.25 1 1 1 1 1 0.2 0.39
ATX2L_MOUSE Ataxin-2-like protein 33 110580 8.94 3 1 3 1 3 0.07 0.04
SELB_MOUSE Selenocysteine-specific elongation factor 33 63498 8.58 2 1 2 1 2 0.09 0.07
TRI16_MOUSE Tripartite motif-containing protein 16 33 62903 5.57 2 1 2 1 2 0.06 0.07
ARSA_MOUSE Arylsulfatase A 33 53714 5.5 3 1 2 1 2 0.1 0.08
BL1S6_MOUSE Biogenesis of lysosome-related organelles complex 1 subunit 6 33 19670 5.91 2 1 1 1 1 0.11 0.23
ECH1_MOUSE Delta(3,5)-delta(2,4)-dienoyl-CoA isomerase, mitochondrial 33 36095 7.6 4 1 4 1 4 0.31 0.12
DIAP3_MOUSE Protein diaphanous homolog 3 32 133601 7.53 3 1 3 1 3 0.05 0.03
ERG1_MOUSE Squalene monooxygenase 32 63730 8.67 5 1 2 1 2 0.1 0.07
DDX46_MOUSE Probable ATP-dependent RNA helicase DDX46 32 117376 9.3 4 1 3 1 3 0.05 0.04
M4K4_MOUSE Mitogen-activated protein kinase 4 32 140515 7.1 7 1 7 1 7 0.1 0.03
ABCD3_MOUSE ATP-binding cassette sub-family D member 3 32 75426 9.32 9 1 7 1 7 0.13 0.06
PSMG1_MOUSE Proteasome assembly chaperone 1 32 33083 6.05 4 2 2 1 2 0.12 0.29
FRDA_MOUSE Frataxin, mitochondrial 32 22910 7.81 1 1 1 1 1 0.08 0.2
THOP1_MOUSE Thimet oligopeptidase 32 77976 5.72 3 2 2 1 2 0.06 0.06
CREL2_MOUSE Cysteine-rich with EGF-like domain protein 2 32 38194 4.49 3 1 2 1 2 0.05 0.11
SSRD_MOUSE Translocon-associated protein subunit delta 32 18924 5.5 4 1 4 1 4 0.31 0.24
I2BP2_MOUSE Interferon regulatory factor 2-binding protein 2 32 59255 9 6 1 5 1 5 0.18 0.07
RL29_MOUSE 60S ribosomal protein L29 31 17576 11.84 2 1 2 1 2 0.17 0.26
B4GT1_MOUSE Beta-1,4-galactosyltransferase 1 31 44383 9.45 3 1 2 1 2 0.07 0.1
HTR5A_MOUSE HEAT repeat-containing protein 5A 31 219754 6.31 6 1 5 1 5 0.06 0.02
SYFB_MOUSE Phenylalanine–tRNA ligase beta subunit 31 65655 6.69 4 2 3 1 3 0.09 0.07
BAG5_MOUSE BAG family molecular chaperone regulator 5 31 50911 5.75 3 1 3 1 3 0.14 0.09
HSPB8_MOUSE Heat shock protein beta-8 31 21520 4.92 1 1 1 1 1 0.13 0.21
SNX7_MOUSE Sorting nexin-7 31 44971 4.99 4 2 2 2 2 0.12 0.2
TMTC3_MOUSE Transmembrane and TPR repeat-containing protein 3 31 104131 8.75 5 2 4 1 4 0.06 0.04
NNMT_MOUSE Nicotinamide N-methyltransferase 31 29579 5.3 4 3 2 2 2 0.16 0.32
WIPI1_MOUSE WD repeat domain phosphoinositide-interacting protein 1 30 48727 6.03 3 2 2 1 2 0.13 0.09
K1468_MOUSE LisH domain and HEAT repeat-containing protein KIAA1468 30 134502 5.2 7 1 5 1 5 0.09 0.03
FKBP3_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP3 30 25132 9.29 6 2 6 2 6 0.42 0.39
FHL2_MOUSE Four and a half LIM domains protein 2 30 32051 7.31 2 1 2 1 2 0.15 0.14
ARI4B_MOUSE AT-rich interactive domain-containing protein 4B 30 147553 4.98 4 1 3 1 3 0.03 0.03
ANX11_MOUSE Annexin A11 29 54045 7.53 2 1 1 1 1 0.05 0.08
RM48_MOUSE 39S ribosomal protein L48, mitochondrial 29 23938 9.45 3 1 1 1 1 0.13 0.19
SEN34_MOUSE tRNA-splicing endonuclease subunit Sen34 29 34176 6.56 2 1 2 1 2 0.13 0.13
HP1B3_MOUSE Heterochromatin protein 1-binding protein 3 29 60829 9.71 5 2 4 2 4 0.16 0.15
COX8A_MOUSE Cytochrome c oxidase subunit 8A, mitochondrial 29 7643 9.74 3 1 1 1 1 0.49 0.69
LSM7_MOUSE U6 snRNA-associated Sm-like protein LSm7 29 11629 5.1 4 2 1 1 1 0.24 0.42
CND1_MOUSE Condensin complex subunit 1 29 155567 5.98 2 1 2 1 2 0.03 0.03
ARSB_MOUSE Arylsulfatase B 29 59609 6.78 2 1 1 1 1 0.05 0.07
RBP2_MOUSE E3 SUMO-protein ligase RanBP2 29 340907 5.82 7 1 7 1 7 0.04 0.01
SRPK1_MOUSE SRSF protein kinase 1 29 73043 5.82 2 1 1 1 1 0.02 0.06
VAC14_MOUSE Protein VAC14 homolog 29 87992 5.75 3 2 2 1 2 0.05 0.05
UBR2_MOUSE E3 ubiquitin-protein ligase UBR2 29 199026 5.9 8 1 5 1 5 0.06 0.02
NCEH1_MOUSE Neutral cholesterol ester hydrolase 1 29 45711 6.56 3 1 1 1 1 0.07 0.1
LMAN1_MOUSE Protein ERGIC-53 29 57753 5.92 7 2 5 2 5 0.21 0.16
DREB_MOUSE Drebrin 29 77239 4.45 2 1 2 1 2 0.06 0.06
AURKB_MOUSE Aurora kinase B 29 39360 9.47 1 1 1 1 1 0.05 0.11
STOM_MOUSE Erythrocyte band 7 integral membrane protein 29 31355 6.45 2 1 2 1 2 0.17 0.14
SETD3_MOUSE Histone-lysine N-methyltransferase setd3 29 67134 5.47 4 2 2 2 2 0.08 0.13
DAAM1_MOUSE Disheveled-associated activator of morphogenesis 1 29 123293 7.12 6 1 5 1 5 0.08 0.03
IF2B2_MOUSE Insulin-like growth factor 2 mRNA-binding protein 2 28 65543 7.81 5 1 4 1 4 0.1 0.07
GSDMD_MOUSE Gasdermin-D 28 53204 5.03 4 2 3 2 3 0.17 0.17
ACON_MOUSE Aconitate hydratase, mitochondrial 28 85410 8.08 8 2 5 2 5 0.12 0.1
IF4B_MOUSE Eukaryotic translation initiation factor 4B 28 68799 5.47 3 1 2 1 2 0.09 0.06
XRCC5_MOUSE X-ray repair cross-complementing protein 5 28 83004 5.04 5 1 5 1 5 0.16 0.05
GALE_MOUSE UDP-glucose 4-epimerase 28 38200 6.27 5 2 2 1 2 0.14 0.11
SYMPK_MOUSE Symplekin 28 142194 5.76 11 1 6 1 6 0.07 0.03
NAA10_MOUSE N-Alpha-acetyltransferase 10 28 26503 5.41 8 3 3 1 3 0.28 0.37
GALD1_MOUSE Glutamine amidotransferase-like class 1 domain-containing protein 1 28 23263 6.58 1 1 1 1 1 0.09 0.19
ZO1_MOUSE Tight junction protein ZO-1 28 194622 6.17 6 1 6 1 6 0.07 0.02
PIGS_MOUSE GPI transamidase component PIG-S 27 61671 6.45 5 2 3 1 3 0.13 0.07
NRP1_MOUSE Neuropilin-1 27 102935 5.6 3 1 3 1 3 0.07 0.04
LEMD2_MOUSE LEM domain-containing protein 2 27 57471 9.18 1 1 1 1 1 0.05 0.08
RTCA_MOUSE RNA 3 -terminal phosphate cyclase 27 39229 8.06 4 1 2 1 2 0.13 0.11
SULF1_MOUSE Extracellular sulfatase Sulf-1 27 100858 9.17 4 1 3 1 3 0.04 0.04
UFC1_MOUSE Ubiquitin-fold modifier-conjugating enzyme 1 27 19469 6.9 5 1 3 1 3 0.28 0.24
IMPA3_MOUSE Inositol monophosphatase 3 27 38592 6.03 2 1 2 1 2 0.14 0.11
RINT1_MOUSE RAD50-interacting protein 1 27 90036 5.02 5 1 4 1 4 0.06 0.05
KCY_MOUSE UMP-CMP kinase 26 22151 5.68 4 1 4 1 4 0.28 0.2
TRIP6_MOUSE Thyroid receptor-interacting protein 6 26 50901 7.03 4 1 2 1 2 0.09 0.09
PLXB2_MOUSE Plexin-B2 26 206099 5.58 7 1 6 1 6 0.07 0.02
UFL1_MOUSE E3 UFM1-protein ligase 1 26 89464 6.24 4 1 3 1 3 0.1 0.05
SMRC2_MOUSE SWI/SNF complex subunit SMARCC2 26 132522 5.41 4 1 4 1 3 0.07 0.03
PPOX_MOUSE Protoporphyrinogen oxidase 26 50839 9.07 1 1 1 1 1 0.06 0.09
PDLI7_MOUSE PDZ and LIM domain protein 7 26 50087 8.82 1 1 1 1 1 0.07 0.09
CLN3_MOUSE Battenin 26 47627 5.25 1 1 1 1 1 0.05 0.09
TRM61_MOUSE tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A 26 31619 6.3 1 1 1 1 1 0.07 0.14
TBRG4_MOUSE Protein TBRG4 26 71468 8.55 2 1 2 1 2 0.04 0.06
AN13A_MOUSE Ankyrin repeat domain-containing protein 13A 26 67136 4.99 1 1 1 1 1 0.03 0.06
TMED3_MOUSE Transmembrane emp24 domain-containing protein 3 26 25449 5.62 2 1 2 1 2 0.16 0.18
NPL4_MOUSE Nuclear protein localization protein 4 homolog 26 67974 6.01 4 1 4 1 4 0.13 0.06
SAP18_MOUSE Histone deacetylase complex subunit SAP18 26 17584 9.38 2 1 2 1 2 0.24 0.26
SUMF2_MOUSE Sulfatase-modifying factor 2 26 34715 6.61 1 1 1 1 1 0.06 0.13
SYMC_MOUSE Methionine–tRNA ligase, cytoplasmic 25 101366 6.78 10 1 8 1 8 0.15 0.04
NOL6_MOUSE Nucleolar protein 6 25 129146 6.33 3 1 3 1 3 0.07 0.03
CRIP2_MOUSE Cysteine-rich protein 2 25 22712 8.94 4 1 4 1 4 0.39 0.2
GSKIP_MOUSE GSK3B-interacting protein 25 15632 4.3 3 1 1 1 1 0.17 0.3
STAR5_MOUSE StAR-related lipid transfer protein 5 25 23907 5.97 3 1 3 1 3 0.18 0.19
LARP4_MOUSE La-related protein 4 25 79713 6.02 2 1 2 1 2 0.06 0.05
OFUT1_MOUSE GDP-fucose protein O-fucosyltransferase 1 25 44660 8.67 1 1 1 1 1 0.05 0.1
RHG10_MOUSE Rho GTPase-activating protein 10 25 89309 6.75 6 1 4 1 4 0.1 0.05
SRA1_MOUSE Steroid receptor RNA activator 1 25 25541 6.01 2 1 2 1 2 0.17 0.18
COR1B_MOUSE Coronin-1B 25 53878 5.54 9 1 6 1 6 0.18 0.08
NIF3L_MOUSE NIF3-like protein 1 25 41719 6.28 4 2 1 1 1 0.05 0.1
LYOX_MOUSE Protein-lysine 6-oxidase 25 46671 8.73 3 1 1 1 1 0.08 0.09
GSH1_MOUSE Glutamate–cysteine ligase catalytic subunit 25 72525 5.59 8 2 3 1 3 0.09 0.06
GIT2_MOUSE ARF GTPase-activating protein GIT2 25 78717 7.64 5 1 5 1 5 0.12 0.05
BL1S2_MOUSE Biogenesis of lysosome-related organelles complex 1 subunit 2 24 16289 4.82 3 2 1 1 1 0.19 0.29
IBP7_MOUSE Insulin-like growth factor-binding protein 7 24 28951 8.71 1 1 1 1 1 0.07 0.15
PLIN3_MOUSE Perilipin-3 24 47233 5.45 8 2 4 2 4 0.24 0.19
TM9S2_MOUSE Transmembrane 9 superfamily member 2 24 75280 7.21 5 2 2 1 2 0.09 0.06
CAP2_MOUSE Adenylyl cyclase-associated protein 2 24 52829 6 3 1 2 1 2 0.06 0.08
LPP_MOUSE Lipoma-preferred partner homolog 24 65848 7.19 7 1 5 1 5 0.17 0.07
STXB3_MOUSE Syntaxin-binding protein 3 24 67899 8.28 5 1 3 1 3 0.12 0.06
EDC4_MOUSE Enhancer of mRNA-decapping protein 4 23 152389 5.51 5 1 4 1 4 0.06 0.03
CO6A2_MOUSE Collagen alpha-2(VI) chain 23 110266 6.01 2 1 2 1 2 0.04 0.04
ATG4B_MOUSE Cysteine protease ATG4B 23 44347 4.93 1 1 1 1 1 0.04 0.1
GGPPS_MOUSE Geranylgeranyl pyrophosphate synthase 23 34685 6.03 2 1 1 1 1 0.09 0.13
TT39B_MOUSE Tetratricopeptide repeat protein 39B 23 70248 6.22 3 1 2 1 2 0.06 0.06
VPS11_MOUSE Vacuolar protein sorting-associated protein 11 homolog 22 107650 6.54 3 1 2 1 2 0.05 0.04
KANK2_MOUSE KN motif and ankyrin repeat domain-containing protein 2 22 90190 5.38 2 1 2 1 2 0.06 0.05
ANO6_MOUSE Anoctamin-6 22 106186 6.34 2 1 1 1 1 0.01 0.04
ACAD8_MOUSE Isobutyryl-CoA dehydrogenase, mitochondrial 22 44990 8.46 1 1 1 1 1 0.06 0.1
BASI_MOUSE Basigin 22 42418 5.56 3 1 1 1 1 0.04 0.1
RO60_MOUSE 60 kDa SS-A/Ro ribonucleoprotein 22 60085 8.11 4 1 3 1 3 0.09 0.07
AHSA2_MOUSE Activator of 90 kDa heat shock protein ATPase homolog 2 22 37624 6.1 2 1 2 1 2 0.11 0.12
CND2_MOUSE Condensin complex subunit 2 21 82251 4.81 2 1 2 1 2 0.05 0.05
TM214_MOUSE Transmembrane protein 214 21 76381 9.41 3 1 2 1 2 0.06 0.06
MPC1_MOUSE Mitochondrial pyruvate carrier 1 21 12446 9.67 3 1 1 1 1 0.19 0.39
PIGT_MOUSE GPI transamidase component PIG-T 21 65663 8.68 1 1 1 1 1 0.03 0.07
UBP4_MOUSE Ubiquitin carboxyl-terminal hydrolase 4 21 108274 5.42 6 2 3 1 3 0.09 0.04
DNLI1_MOUSE DNA ligase 1 21 102226 6.43 1 1 1 1 1 0.02 0.04
FUCO_MOUSE Tissue alpha-L-fucosidase 20 52247 6.47 1 1 1 1 1 0.04 0.08
CEBPZ_MOUSE CCAAT/enhancer-binding protein zeta 20 120187 5.53 5 1 3 1 3 0.08 0.04
E2AK2_MOUSE Interferon-induced, double-stranded RNA-activated protein kinase 20 58243 8.76 4 1 3 1 3 0.12 0.07
AFG31_MOUSE AFG3-like protein 1 20 86992 9 1 1 1 1 1 0.02 0.05
RICTR_MOUSE Rapamycin-insensitive companion of mTOR 20 191449 6.8 9 1 5 1 5 0.05 0.02
NOC4L_MOUSE Nucleolar complex protein 4 homolog 19 58638 6.29 3 1 1 1 1 0.04 0.07
SOAT1_MOUSE Sterol O-acyltransferase 1 19 63757 9.15 6 1 4 1 4 0.15 0.07
SH3G1_MOUSE Endophilin-A2 19 41492 5.53 2 1 1 1 1 0.04 0.11
ILVBL_MOUSE Acetolactate synthase-like protein 19 68113 8.96 2 1 2 1 2 0.09 0.06
LASP1_MOUSE LIM and SH3 domain protein 1 19 29975 6.61 6 1 5 1 5 0.19 0.15
NUMA1_MOUSE Nuclear mitotic apparatus protein 1 18 235487 5.68 10 1 10 1 10 0.08 0.02
DPP8_MOUSE Dipeptidyl peptidase 8 18 102121 5.51 3 1 2 1 2 0.04 0.04
MTX2_MOUSE Metaxin-2 18 29739 5.44 1 1 1 1 1 0.11 0.15
RM15_MOUSE 39S ribosomal protein L15, mitochondrial 18 33521 10.08 2 1 2 1 2 0.1 0.13
PM34_MOUSE Peroxisomal membrane protein PMP34 17 34391 10.11 1 1 1 1 1 0.07 0.13
PPP5_MOUSE Serine/threonine-protein phosphatase 5 17 56840 5.83 4 1 4 1 4 0.17 0.08
DOK1_MOUSE Docking protein 1 16 52419 6.16 4 1 3 1 3 0.14 0.08
LEG9_MOUSE Galectin-9 16 40010 9.41 3 1 1 1 1 0.06 0.11
PGM2_MOUSE Phosphoglucomutase-2 16 68704 5.78 2 1 2 1 2 0.08 0.06
HSP7E_MOUSE Heat shock 70 kDa protein 14 16 54616 5.63 4 1 4 1 4 0.17 0.08
PUM2_MOUSE Pumilio homolog 2 15 114243 6.61 3 1 3 1 3 0.08 0.04
  • aProtein score is calculated from the score of the peptide attributed to the protein. bpI is (predicted) isoelectric point. cNumber of matches is spectrum number matched to protein#1. dNumber of significant matches is spectrum number that matches protein and exceeds the identification criteria. eNumber of sequences is number of peptides matched to protein#2. fNumber of significant sequences is number of peptides exceeding the identification criteria matched to proteins. gNumber of unique sequences is a unique#3 number of peptides matched to proteins. hSequence coverage is the ratio of the total number of matched peptide residues to the total length of the protein. iExponentially modified protein abundance index (http://www.matrixscience.com/help/quant_empai_help.html). #1When multiple spectra are matched to the same peptide, the way of counting into one is called "peptide number". #2When multiple spectra are matched to the same peptide, the method of counting is called "spectrum number". #3"Unique" is a peptide that is not matched to other proteins and has been assigned only to the relevant protein.
Details are in the caption following the image
Venn diagram of proteins detected on LC-MS/MS. There were 1785 types of proteins identified from the mouse primary cultured cell (P0) sample and 1825 types of proteins identified from samples of cells passaged 3 times (P3). Among the 1785 types of proteins in mouse P0 cells, there were 336 types of proteins unique to the primary cultured cells (group P0). A total of 1449 types of proteins in mouse P0 cells were also identified in mouse P3 cells (group P0&P3). Among the 1825 types of proteins in mouse P3 cells, there were 376 types of proteins unique to the cells passaged 3 times (group P3).

The amount of protein quantified in this paper is a theoretical value estimated based on the emPAI function of the Scaffold software program. The ratio of the number of measured peptides to the number of theoretical peptides is linearly related to the logarithm of the protein concentration, and the number obtained by subtracting 1 from the index of the peptide number ratio was defined as the emPAI. The larger the emPAI value, the greater the amount of protein. We recently published a paper on the correlation between different emPAI values (>0, >1, >2, >3, >5, and >10) and the results of protein expression analyses. The results showed that, for an emPAI value > 10, the presence of protein can be detected with a high probability, even if the number of samples is n = 1 [25]. Proteins quantified using emPAI were listed from the top in the tables showing the GO analysis results (Tables 1 and 2) in descending order of concentration. Since the data of this study were derived from a single protein expression analysis obtained from mMSC-ATs of three mice, the data reliability must be carefully considered.

3.4. The Biological Processes, Cellular Components, and Molecular Function of Proteins Identified from mMSC-ATs (P0)

The biological processes of proteins were analyzed using the Mascot software program with the SwissProt 2017 database.

3.4.1. Biological Processes

Antiviral protein was detected as a protein component of mMSC-ATs (P0) (rich in components of SVF). Isg15, Npc2, Ripk3, Fmr1, Dag1, Vps16, Gas6, Stmn1, Vapb, Tri25, Eea1, Asc, Ifm2, Bst2, Apoe, Ltor5, Oas1a, and Nect2 were detected as factors related to the viral process (Figure 3).

Details are in the caption following the image
The biological processes, cellular components, and molecular function of the mouse primary cultured cell (P0) proteins (as determined by GO). The PCA of proteome dynamics based on the protein information generated by high-resolution mass spectrometry. The ordinate indicates the biological function, cellular component, and molecular function of the protein. The abscissa indicates the number of identified proteins. The names of the proteins classified in Table 3 are listed by their detailed molecular functions.

Stml2 (CD4-positive, alpha-beta T cell activation), CD36, CD180 (B cell proliferation), CD47 (opsonization), and CD166 (adaptive immune response) were detected as factors related to the CD cell surface markers related to the immune system. Cats, Ha1b, Erap1, Mdr1a, Psb8, and Ha11 were detected as factors related to the MHC class antigen and thereby related to the immune system. Csf1 (osteoclast differentiation), CD109 (osteoclast fusion), and Rab35 (antigen processing and presentation) were detected as factors related to the bone immune system. Isg15, Tri25, Ifm2, Bst2, Oas1a, and Asc were detected as factors related to the antiviral immune system. Tgbr3, Plek (hematopoietic progenitor cell differentiation), Ripk3 (T cell differentiation in thymus), Gas6 (macrophage cytokine production), Sfxn1 (erythrocyte differentiation), Ada (T cell activation, B cell differentiation), Itam (activated T cell proliferation), Pfd1 (B cell activation), Sbds (leukocyte chemotaxis), Aimp1 (leukocyte migration), Armc6 (hematopoietic progenitor cell differentiation), Glrx5 (hemopoiesis), Hdac7 (B cell activation, B cell differentiation), Psn1 (T cell activation), Ada10 (monocyte activation), and Tpd52 (B cell differentiation) were detected as factors related to hematopoiesis. A4, Ada15, Ptms (immune system process), Fcgrn (antigen processing and presentation), Il4ra, Ilf2, Ic1 (complement activation), Olr1, and Snp23 (histamine secretion by mast cell) were detected as factors related to the immune response. Stat1 was detected as an interferon-related immune response factor. Those proteins were detected as factors related to the immune system process (Figure 3).

Csf1 (mammary duct terminal end bud growth), Tgbr3 (cardiac muscle cell proliferation), A4 (synaptic growth at neuromuscular junction), Ada15 (tissue regeneration), CD166 (axon extension involved in axon guidance, neuron projection extension), Tbl1r (multicellular organism growth), Ninj1 (tissue regeneration), and Sbds (inner cell mass cell proliferation) were detected as factors related to growth in biological processes (Figure 3).

3.4.2. Cellular Components

Stml2 (T cell receptor complex), Stx7 (immunological synapse), Ha1b (MHC class I protein complex), Ha11 (MHC class I protein complex), CD166 (T cell receptor complex), At2b1 (apical plasma membrane), Gna11 (heterotrimeric G-protein complex), Home3 (postsynaptic membrane), Ampn, Rdh11, Nsf1c, Bag3, Csf1, Vatc1, Necp2, CD109, CD36, Ece1, Tgbr3, A4, Ripk3, Gdn, Erln2, Aaat, Suca, Snp23, Prio, Ly6a, Plp2, Plek, Tpbg, Fmr1, Plin4, Ldlr, Pdc10, Dag1, Rap2a, Vatg1, Pp2ba, Rab35, Il1ap, Eea1, Fcgrn, Ada, Cdv3, Erap1, Ifm2, Bst2, CD180, Il4ra, Itam, Osmr, P2rx4, Serc1, Tradd, CD97, Rab4b, Rab8a, Sucb2, Apoe, Bap31, Cdipt, Cn37, Crk, Dnjb4, Ggt5, Mdr1a, Piez1, Praf1, Psn1, S39ae, Stx2, Tnr12, Vmp1, Fen1, CD47, Olr1, Pygl, Wwox, Ctl1, Ly6c1, Nect2, and Ttyh2 (plasma membrane) were detected as factors related to growth in the plasma membrane of the cellular component (Figure 3).

3.4.3. Molecular Functions

SRXN1 (antioxidant activity), TXD17 (peroxidase activity), PGFS (thioredoxin peroxidase activity), and APOE (antioxidant activity) are proteins that are expressed on the plasma membrane. These proteins have been reported to be factors related to both growth and the antioxidant activity according to a classification of the molecular functions (Figure 3). The proteins of mMSC-ATs (P0) are listed in Table 3 with their molecular functions described in detail.

Table 3. Identification of endogenous proteins contained in mMSC-AT_P0 only, not in mMSC-AT_P3.
Exclusive P0 group
UniProt/Swiss-Prot ID Description Molecular function
FABP5_MOUSE Fatty acid-binding protein, epidermal Fatty acid binding, transporter activity
AMPN_MOUSE Aminopeptidase N Metal ion binding, metalloaminopeptidase activity, metallopeptidase activity, peptide binding, zinc ion binding
AOFA_MOUSE Amine oxidase [flavin-containing] A Oxidoreductase activity, primary amine oxidase activity, protein binding
HXK3_MOUSE Hexokinase-3 ATP binding, fructokinase activity, glucokinase activity, glucose binding, kinase activity, mannokinase activity, nucleotide binding
CTGF_MOUSE Connective tissue growth factor Fibronectin binding, growth factor activity, heparin binding, insulin-like growth factor binding, integrin binding, protein C-terminus binding
THIL_MOUSE Acetyl-CoA acetyltransferase, mitochondrial Acetyl-CoA C-acetyltransferase activity, carbon-carbon lyase activity, coenzyme binding, enzyme binding, ligase activity, forming carbon-carbon bonds, metal ion binding, protein homodimerization activity, transferase activity, transferring acyl groups
ATPD_MOUSE ATP synthase subunit delta, mitochondrial ATPase activity, hydrogen ion transmembrane transporter activity, proton-transporting ATP synthase activity, rotational mechanism
CATS_MOUSE Cathepsin S Collagen binding, cysteine-type endopeptidase activity, cysteine-type peptidase activity, fibronectin binding, hydrolase activity, laminin binding, proteoglycan binding
CYR61_MOUSE Protein CYR61 Extracellular matrix binding, growth factor binding, heparin binding, insulin-like growth factor binding, integrin binding
ETFB_MOUSE Electron transfer flavoprotein subunit beta Electron carrier activity
SFXN3_MOUSE Sideroflexin-3 Ion transmembrane transporter activity, molecular function
STML2_MOUSE Stomatin-like protein 2, mitochondrial GTPase binding, cardiolipin binding, lipid binding
RDH11_MOUSE Retinol dehydrogenase 11 NADP-retinol dehydrogenase activity, retinol dehydrogenase activity
NSF1C_MOUSE NSFL1 cofactor p47 ATPase binding, lipid binding, phospholipid binding, ubiquitin binding
BAG3_MOUSE BAG family molecular chaperone regulator 3 Adenyl-nucleotide exchange factor activity, cadherin binding involved in cell-cell adhesion, chaperone binding, protein complex binding
CSF1_MOUSE Macrophage colony-stimulating factor 1 Cytokine activity, growth factor activity, macrophage colony-stimulating factor receptor binding, protein homodimerization activity
LYZ2_MOUSE Lysozyme C-2 Hydrolase activity, identical protein binding, lysozyme activity
VATC1_MOUSE V-type proton ATPase subunit C 1 Hydrogen-exporting ATPase activity, phosphorylative mechanism
UBP2L_MOUSE Ubiquitin-associated protein 2-like RNA binding
RL28_MOUSE 60S ribosomal protein L28 RNA binding, structural constituent of ribosome
ACSL4_MOUSE Long-chain-fatty-acid–CoA ligase 4 ATP binding, arachidonate-CoA ligase activity, decanoate–CoA ligase activity, ligase activity, long-chain fatty acid-CoA ligase activity, nucleotide binding, very-long-chain fatty acid-CoA ligase activity
THIKA_MOUSE 3-Ketoacyl-CoA thiolase A, peroxisomal Acetate CoA-transferase activity, acetyl-CoA C-acetyltransferase activity, acetyl-CoA C-acyltransferase activity, palmitoyl-CoA oxidase activity
FA49B_MOUSE Protein FAM49B Protein binding
CO5A2_MOUSE Collagen alpha-2(V) chain SMAD binding, extracellular matrix structural constituent, metal ion binding
DCTN2_MOUSE Dynactin subunit 2 Motor activity, spectrin binding
SUCB1_MOUSE Succinate–CoA ligase [ADP-forming] subunit beta, mitochondrial ATP binding, ligase activity, metal ion binding, nucleotide binding, succinate-CoA ligase (ADP-forming) activity
SYUG_MOUSE Gamma-synuclein Protein binding
GUAD_MOUSE Guanine deaminase Guanine deaminase activity, hydrolase activity, metal ion binding, zinc ion binding
ISG15_MOUSE Ubiquitin-like protein ISG15 Protein binding, protein tag
STK24_MOUSE Serine/threonine-protein kinase 24 ATP binding, cadherin binding involved in cell-cell adhesion, metal ion binding, nucleotide binding, signal transducer, downstream of receptor, with serine/threonine kinase activity, transferase activity
STX7_MOUSE Syntaxin-7 SNAP receptor activity, chloride channel inhibitor activity, syntaxin binding
EFHD2_MOUSE EF-hand domain-containing protein D2 Cadherin binding involved in cell-cell adhesion, calcium ion binding, metal ion binding
NECP2_MOUSE Adaptin ear-binding coat-associated protein 2 Molecular function
ATP5J_MOUSE ATP synthase-coupling factor 6, mitochondrial ATPase activity, hydrogen ion transmembrane transporter activity
ERH_MOUSE Enhancer of rudimentary homolog RNA binding, methyl-CpG binding
HAP28_MOUSE 28 kDa heat- and acid-stable phosphoprotein RNA binding, platelet-derived growth factor binding
TOM20_MOUSE Mitochondrial import receptor subunit TOM20 homolog P-P-bond-hydrolysis-driven protein transmembrane transporter activity, mitochondrion targeting sequence binding, protein channel activity, unfolded protein binding
CD109_MOUSE CD109 antigen Serine-type endopeptidase inhibitor activity, transforming growth factor beta binding
CD36_MOUSE Platelet glycoprotein 4 High-density lipoprotein particle binding, lipid binding, lipoteichoic acid receptor activity, low-density lipoprotein particle binding, low-density lipoprotein receptor activity, protein binding
ECE1_MOUSE Endothelin-converting enzyme 1 Metal ion binding, metalloendopeptidase activity, metallopeptidase activity, protein homodimerization activity
STX12_MOUSE Syntaxin-12 SNAP receptor activity, SNARE binding, protein binding
TOM1_MOUSE Target of Myb protein 1 Clathrin binding
CO3A1_MOUSE Collagen alpha-1(III) chain SMAD binding, extracellular matrix structural constituent, integrin binding, metal ion binding, platelet-derived growth factor binding
NPC2_MOUSE Epididymal secretory protein E1 Cholesterol binding, enzyme binding
HA1B_MOUSE H-2 class I histocompatibility antigen, K-B alpha chain RNA binding, beta-2-microglobulin binding, peptide antigen binding, receptor binding
VKOR1_MOUSE Vitamin K epoxide reductase complex subunit 1 Oxidoreductase activity, quinone binding, vitamin-K-epoxide reductase (warfarin-sensitive) activity
CUL3_MOUSE Cullin-3 POZ domain binding, cyclin binding, protein binding, protein heterodimerization activity, protein homodimerization activity, ubiquitin protein ligase activity, ubiquitin protein ligase binding
HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain RNA binding, beta-2-microglobulin binding, peptide antigen binding, protein binding
ACAD9_MOUSE Acyl-CoA dehydrogenase family member 9, mitochondrial Acyl-CoA dehydrogenase activity, electron carrier activity, fatty-acyl-CoA binding, flavin adenine dinucleotide binding, oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
TGBR3_MOUSE Transforming growth factor beta receptor type 3 PDZ domain binding, SMAD binding, coreceptor activity, glycosaminoglycan binding, protein binding, transforming growth factor beta binding, transforming growth factor beta receptor activity, type III, transforming growth factor beta-activated receptor activity, type II transforming growth factor beta receptor binding
A4_MOUSE Amyloid-beta A4 protein DNA binding, PTB domain binding, enzyme binding, growth factor receptor binding, heparin binding, identical protein binding, peptidase activator activity, peptidase inhibitor activity, serine-type endopeptidase inhibitor activity, transition metal ion binding
RBMS2_MOUSE RNA-binding motif, single-stranded-interacting protein 2 RNA binding, nucleotide binding
PAPS2_MOUSE Bifunctional 3 -phosphoadenosine 5 -phosphosulfate synthase 2 ATP binding, adenylylsulfate kinase activity, catalytic activity, nucleotide binding, nucleotidyltransferase activity, sulfate adenylyltransferase (ATP) activity
SPA3N_MOUSE Serine protease inhibitor A3N Peptidase inhibitor activity, serine-type endopeptidase inhibitor activity
DDX17_MOUSE Probable ATP-dependent RNA helicase DDX17 ATP binding, ATP-dependent RNA helicase activity, RNA binding, estrogen receptor binding, nucleotide binding, transcription coactivator activity
RIPK3_MOUSE Receptor-interacting serine/threonine-protein kinase 3 ATP binding, NF-kappaB-inducing kinase activity, identical protein binding, nucleotide binding, protein complex binding
MCAT_MOUSE Mitochondrial carnitine/acylcarnitine carrier protein Acyl carnitine transmembrane transporter activity
GDN_MOUSE Glia-derived nexin Glycosaminoglycan binding, heparin binding, receptor binding, serine-type endopeptidase inhibitor activity
ERLN2_MOUSE Erlin-2 Cholesterol binding, protein binding, ubiquitin protein ligase binding
ARPC5_MOUSE Actin-related protein 2/3 complex subunit 5 Actin filament binding, structural constituent of cytoskeleton
AAAT_MOUSE Neutral amino acid transporter B(0) Neutral amino acid transmembrane transporter activity, symporter activity
NAGK_MOUSE N-Acetyl-D-glucosamine kinase ATP binding, N-acetylglucosamine kinase activity, N-acylmannosamine kinase activity, kinase activity, nucleotide binding
STAT1_MOUSE Signal transducer and activator of transcription 1 DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter sequence-specific DNA binding, cadherin binding involved in cell-cell adhesion, double-stranded DNA binding, enzyme binding, nuclear hormone receptor binding, protein homodimerization activity, signal transducer activity, transcription factor activity, RNA polymerase II core promoter sequence-specific, transcription factor activity, sequence-specific DNA binding, tumor necrosis factor receptor binding
CCD47_MOUSE Coiled-coil domain-containing protein 47 RNA binding, calcium ion binding
NDUB7_MOUSE NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NADH dehydrogenase (ubiquinone) activity
F13A_MOUSE Coagulation factor XIII A chain Metal ion binding, protein-glutamine gamma-glutamyltransferase activity
SUCA_MOUSE Succinate–CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial GTP binding, RNA binding, cofactor binding, ligase activity, nucleotide binding, succinate-CoA ligase (ADP-forming) activity, succinate-CoA ligase (GDP-forming) activity
FACR1_MOUSE Fatty acyl-CoA reductase 1 Fatty-acyl-CoA reductase (alcohol-forming) activity, long-chain-fatty-acyl-CoA reductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
EFTS_MOUSE Elongation factor Ts, mitochondrial RNA binding, translation elongation factor activity
TM165_MOUSE Transmembrane protein 165 Molecular function
ADA15_MOUSE Disintegrin and metalloproteinase domain-containing protein 15 SH3 domain binding, integrin binding, metal ion binding, metalloendopeptidase activity, metallopeptidase activity, peptidase activity, protein binding
SNP23_MOUSE Synaptosomal-associated protein 23 SNAP receptor activity, syntaxin binding
PRIO_MOUSE Major prion protein ATP-dependent protein binding, chaperone binding, copper ion binding, identical protein binding, ion channel binding, lamin binding, microtubule binding
LY6A_MOUSE Lymphocyte antigen 6A-2/6E-1
PLP2_MOUSE Proteolipid protein 2 Chemokine binding
TSNAX_MOUSE Translin-associated protein X A2A adenosine receptor binding, RNA binding, metal ion binding, protein complex binding, sequence-specific DNA binding, single-stranded DNA binding
T106A_MOUSE Transmembrane protein 106A Molecular function
UBFD1_MOUSE Ubiquitin domain-containing protein UBFD1 RNA binding, cadherin binding involved in cell-cell adhesion
PLEK_MOUSE Pleckstrin Phosphatidylinositol-3,4-bisphosphate binding, protein homodimerization activity, protein kinase C binding
TPBG_MOUSE Trophoblast glycoprotein
ILEUA_MOUSE Leukocyte elastase inhibitor A Serine-type endopeptidase inhibitor activity
TIMP2_MOUSE Metalloproteinase inhibitor 2 Enzyme activator activity, integrin binding, metal ion binding, metalloendopeptidase inhibitor activity, peptidase inhibitor activity, protease binding
FMR1_MOUSE Synaptic functional regulator FMR1 G-quadruplex RNA binding, RNA stem-loop binding, RNA strand annealing activity, chromatin binding, dynein complex binding, ion channel binding, mRNA 3 -UTR binding, mRNA 5 -UTR binding, methylated histone binding, miRNA binding, microtubule binding, poly(G) binding, poly(U) RNA binding, protein heterodimerization activity, protein homodimerization activity, ribosome binding, sequence-specific mRNA binding, siRNA binding, translation initiation factor binding, translation repressor activity
DCUP_MOUSE Uroporphyrinogen decarboxylase Carboxy-lyase activity, uroporphyrinogen decarboxylase activity
PLIN4_MOUSE Perilipin-4
RHEB_MOUSE GTP-binding protein Rheb GTP binding, metal ion binding, nucleotide binding, protein kinase binding
TPD52_MOUSE Tumor protein D52 Calcium ion binding, protein binding, protein heterodimerization activity, protein homodimerization activity
LDLR_MOUSE Low-density lipoprotein receptor Calcium ion binding, glycoprotein binding, identical protein binding, low-density lipoprotein particle binding, low-density lipoprotein receptor activity, protease binding, very-low-density lipoprotein particle receptor activity
PDC10_MOUSE Programmed cell death protein 10 Protein N-terminus binding, protein homodimerization activity, protein kinase binding
UFM1_MOUSE Ubiquitin-fold modifier 1 Molecular function
SRXN1_MOUSE Sulfiredoxin-1 ATP binding, antioxidant activity, nucleotide binding, oxidoreductase activity, oxidoreductase activity, acting on a sulfur group of donors, sulfiredoxin activity
GAPR1_MOUSE Golgi-associated plant pathogenesis-related protein 1 Protein homodimerization activity
CSN5_MOUSE COP9 signalosome complex subunit 5 Hydrolase activity, metal ion binding, metallopeptidase activity, protein binding, thiol-dependent ubiquitin-specific protease activity, transcription coactivator activity
OCAD1_MOUSE OCIA domain-containing protein 1 Molecular function
DCAKD_MOUSE Dephospho-CoA kinase domain-containing protein ATP binding, dephospho-CoA kinase activity, nucleotide binding
CD166_MOUSE CD166 antigen Protein binding
ATG3_MOUSE Ubiquitin-like-conjugating enzyme ATG3 Atg12 transferase activity, Atg8 ligase activity, enzyme binding, ligase activity, ubiquitin-like protein transferase activity
DAG1_MOUSE Dystroglycan SH2 domain binding, actin binding, alpha-actinin binding, calcium ion binding, dystroglycan binding, protein binding, protein complex binding, structural constituent of muscle, tubulin binding, vinculin binding
RAP2A_MOUSE Ras-related protein Rap-2a GTP binding, GTPase activity, nucleotide binding, protein binding
MPEG1_MOUSE Macrophage-expressed gene 1 protein
RBX1_MOUSE E3 ubiquitin-protein ligase RBX1 NEDD8 transferase activity, cullin family protein binding, eukaryotic initiation factor 4E binding, ligase activity, protein complex binding, ubiquitin protein ligase activity, ubiquitin protein ligase binding, ubiquitin-ubiquitin ligase activity, zinc ion binding
VPS16_MOUSE Vacuolar protein sorting-associated protein 16 homolog Actin binding
PKHO2_MOUSE Pleckstrin homology domain-containing family O member 2 Molecular function
GAS6_MOUSE Growth arrest-specific protein 6 Binding, bridging, calcium ion binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, phosphatidylserine binding, protein tyrosine kinase activator activity, receptor agonist activity, receptor binding, receptor tyrosine kinase binding, voltage-gated calcium channel activity
GMPPA_MOUSE Mannose-1-phosphate guanyltransferase alpha Nucleotidyltransferase activity, transferase activity
COMD4_MOUSE COMM domain-containing protein 4 Molecular function
MECR_MOUSE Enoyl-[acyl-carrier-protein] reductase, mitochondrial Ligand-dependent nuclear receptor binding, oxidoreductase activity, trans-2-enoyl-CoA reductase (NADPH) activity, zinc ion binding
PTMS_MOUSE Parathymosin Zinc ion binding
RMD3_MOUSE Regulator of microtubule dynamics protein 3 Molecular function
SRSF1_MOUSE Serine/arginine-rich splicing factor 1 RNA binding, RS domain binding, mRNA binding, nucleotide binding, protein kinase B binding
TMCO1_MOUSE Calcium load-activated calcium channel Calcium channel activity
TMX1_MOUSE Thioredoxin-related transmembrane protein 1 Disulfide oxidoreductase activity, protein disulfide isomerase activity
VATG1_MOUSE V-type proton ATPase subunit G 1 ATPase activity, ATPase binding, hydrogen-exporting ATPase activity, phosphorylative mechanism, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
STMN1_MOUSE Stathmin Protein binding, tubulin binding
H14_MOUSE Histone H1.4 DNA binding, RNA binding, chromatin DNA binding, protein binding
PROS_MOUSE Vitamin K-dependent protein S Calcium ion binding
PP2BA_MOUSE Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Calcium-dependent protein serine/threonine phosphatase activity, calmodulin binding, calmodulin-dependent protein phosphatase activity, drug binding, enzyme binding, hydrolase activity, metal ion binding, protein dimerization activity, protein heterodimerization activity
VAPB_MOUSE Vesicle-associated membrane protein-associated protein B FFAT motif binding, beta-tubulin binding, cadherin binding involved in cell-cell adhesion, enzyme binding, microtubule binding, protein heterodimerization activity, protein homodimerization activity
TBL1R_MOUSE F-box-like/WD repeat-containing protein TBL1XR1 DNA binding, beta-catenin binding, histone binding, protein N-terminus binding, protein binding, transcription corepressor activity, transcription regulatory region DNA binding
RAB35_MOUSE Ras-related protein Rab-35 GDP binding, GTP binding, GTPase activity, nucleotide binding, phosphatidylinositol-4,5-bisphosphate binding, protein binding
BID_MOUSE BH3-interacting domain death agonist Protein heterodimerization activity, ubiquitin protein ligase binding
GLTP_MOUSE Glycolipid transfer protein Glycolipid binding, glycolipid transporter activity
IL1RA_MOUSE Interleukin-1 receptor antagonist protein Cytokine activity, interleukin-1 Type I receptor antagonist activity, interleukin-1 Type II receptor antagonist activity, interleukin-1, Type I receptor binding, interleukin-1, Type II receptor binding
PDXK_MOUSE Pyridoxal kinase ATP binding, kinase activity, lithium ion binding, magnesium ion binding, nucleotide binding, potassium ion binding, protein homodimerization activity, pyridoxal kinase activity, pyridoxal phosphate binding, sodium ion binding, zinc ion binding
TRI25_MOUSE E3 ubiquitin/ISG15 ligase TRIM25 RNA binding, acid-amino acid ligase activity, cadherin binding involved in cell-cell adhesion, ligase activity, metal ion binding, ubiquitin protein ligase activity involved in ERAD pathway, ubiquitin-protein transferase activity, zinc ion binding
VATD_MOUSE V-type proton ATPase subunit D ATPase activity, coupled to transmembrane movement of substances
IL1AP_MOUSE Interleukin-1 receptor accessory protein Interleukin-1 receptor activity, interleukin-33 receptor activity, protein tyrosine kinase binding, signal transducer activity
SFXN1_MOUSE Sideroflexin-1 Ion transmembrane transporter activity
EEA1_MOUSE Early endosome antigen 1 1-Phosphatidylinositol binding, GTP-dependent protein binding, metal ion binding, protein homodimerization activity
CBR2_MOUSE Carbonyl reductase [NADPH] 2 Carbonyl reductase (NADPH) activity, oxidoreductase activity, protein binding, protein self-association
FKB14_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP14 FK506 binding, calcium ion binding, isomerase activity, peptidyl-prolyl cis-trans isomerase activity
DEGS1_MOUSE Sphingolipid delta(4)-desaturase DES1 Sphingolipid delta-4 desaturase activity
FCGRN_MOUSE IgG receptor FcRn large subunit p51 IgG binding, IgG receptor activity, antigen binding, beta-2-microglobulin binding, peptide antigen binding
ACSF2_MOUSE Acyl-CoA synthetase family member 2, mitochondrial ATP binding, ligase activity, molecular function, nucleotide binding
ADA_MOUSE Adenosine deaminase Adenosine deaminase activity, deaminase activity, hydrolase activity, purine nucleoside binding, zinc ion binding
ASC_MOUSE Apoptosis-associated speck-like protein containing a CARD BMP receptor binding, Pyrin domain binding, cysteine-type endopeptidase activity involved in apoptotic process, enzyme binding, interleukin-6 receptor binding, ion channel binding, myosin I binding, peptidase activator activity involved in apoptotic process, protease binding, protein dimerization activity, protein homodimerization activity, tropomyosin binding
TXD17_MOUSE Thioredoxin domain-containing protein 17 Peroxidase activity, protein-disulfide reductase activity
MXRA8_MOUSE Matrix remodeling-associated protein 8 Molecular function
COX6C_MOUSE Cytochrome c oxidase subunit 6C Cytochrome c oxidase activity, molecular function
COASY_MOUSE Bifunctional coenzyme A synthase ATP binding, dephospho-CoA kinase activity, nucleotide binding, pantetheine-phosphate adenylyltransferase activity, transferase activity
CHCH2_MOUSE Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 Sequence-specific DNA binding, transcription factor binding
SHOC2_MOUSE Leucine-rich repeat protein SHOC-2 Protein phosphatase 1 binding, protein phosphatase binding
CDV3_MOUSE Protein CDV3 Molecular function
ERAP1_MOUSE Endoplasmic reticulum aminopeptidase 1 Endopeptidase activity, interleukin-6 receptor binding, metalloaminopeptidase activity, metalloexopeptidase activity, peptide binding, zinc ion binding
AL3A2_MOUSE Fatty aldehyde dehydrogenase 3-Chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase [NAD(P)+] activity, long-chain-alcohol oxidase activity
ABHEB_MOUSE Protein ABHD14B Hydrolase activity
GLYG_MOUSE Glycogenin-1 Glycogenin glucosyltransferase activity, metal ion binding, transferase activity, transferase activity, transferring glycosyl groups
BPNT1_MOUSE 3 (2 ),5 -Bisphosphate nucleotidase 1 3 (2 ),5 -Bisphosphate nucleotidase activity, hydrolase activity, magnesium ion binding, metal ion binding
IFM2_MOUSE Interferon-induced transmembrane protein 2 Molecular function
PFD6_MOUSE Prefoldin subunit 6 Chaperone binding, unfolded protein binding
COMD8_MOUSE COMM domain-containing protein 8 Molecular function
S10AD_MOUSE Protein S100-A13 RAGE receptor binding, calcium ion binding, copper ion binding, fibroblast growth factor binding, lipid binding, metal ion binding, protein homodimerization activity, zinc ion binding
T176A_MOUSE Transmembrane protein 176A Protein binding
SPD2B_MOUSE SH3 and PX domain-containing protein 2B SH2 domain binding, phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4-phosphate binding, phosphatidylinositol-5-phosphate binding, superoxide-generating NADPH oxidase activator activity
RM46_MOUSE 39S ribosomal protein L46, mitochondrial Hydrolase activity, structural constituent of ribosome
ADAS_MOUSE Alkyldihydroxyacetonephosphate synthase, peroxisomal FAD binding, alkylglycerone-phosphate synthase activity, flavin adenine dinucleotide binding, oxidoreductase activity, acting on CH-OH group of donors
APMAP_MOUSE Adipocyte plasma membrane-associated protein Arylesterase activity, hydrolase activity, acting on ester bonds, strictosidine synthase activity
ARK72_MOUSE Aflatoxin B1 aldehyde reductase member 2 Oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, phenanthrene-9,10-epoxide hydrolase activity
BST2_MOUSE Bone marrow stromal antigen 2 RNA binding, metalloendopeptidase inhibitor activity, protein homodimerization activity, signal transducer activity
CASP1_MOUSE Caspase-1 Cysteine-type endopeptidase activity, cysteine-type endopeptidase activity involved in apoptotic process, cysteine-type peptidase activity, protein binding
CD180_MOUSE CD180 antigen Receptor activity
CK054_MOUSE Ester hydrolase C11orf54 homolog Hydrolase activity, acting on ester bonds, metal ion binding, zinc ion binding
COX7C_MOUSE Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase activity
CPSF7_MOUSE Cleavage and polyadenylation specificity factor subunit 7 RNA binding, nucleotide binding
DCAF8_MOUSE DDB1- and CUL4-associated factor 8 Molecular function
DHB11_MOUSE Estradiol 17-beta-dehydrogenase 11 Estradiol 17-beta-dehydrogenase activity, steroid dehydrogenase activity
ERGI1_MOUSE Endoplasmic reticulum-Golgi intermediate compartment protein 1 Molecular function
ERGI3_MOUSE Endoplasmic reticulum-Golgi intermediate compartment protein 3 Molecular function
FKB15_MOUSE FK506-binding protein 15 Actin binding, peptidyl-prolyl cis-trans isomerase activity
GSTA1_MOUSE Glutathione S-transferase A1 Glutathione transferase activity, transferase activity
IL4RA_MOUSE Interleukin-4 receptor subunit alpha Cytokine receptor activity, protein binding
ILF2_MOUSE Interleukin enhancer-binding factor 2 ATP binding, DNA binding, RNA binding, double-stranded RNA binding, transferase activity
ITAM_MOUSE Integrin alpha-M Glycoprotein binding, heparan sulfate proteoglycan binding, heparin binding, metal ion binding, opsonin binding
LSG1_MOUSE Large subunit GTPase 1 homolog GTP binding, GTPase activity, nucleotide binding
NDUA2_MOUSE NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase (ubiquinone) activity
NINJ1_MOUSE Ninjurin-1
OSMR_MOUSE Oncostatin-M-specific receptor subunit beta Cytokine binding, cytokine receptor activity, growth factor binding, oncostatin-M receptor activity
P2RX4_MOUSE P2X purinoceptor 4 ATP binding, cadherin binding, extracellular ATP-gated cation channel activity, ion channel activity, purinergic nucleotide receptor activity
PFD1_MOUSE Prefoldin subunit 1 Protein binding involved in protein folding, unfolded protein binding
PGFS_MOUSE Prostamide/prostaglandin F synthase Prostaglandin-F synthase activity, thioredoxin peroxidase activity
PR2C2_MOUSE Prolactin-2C2 Growth factor activity, hormone activity
PRRX1_MOUSE Paired mesoderm homeobox protein 1 DNA binding, HMG box domain binding, RNA polymerase II transcription coactivator activity, sequence-specific DNA binding
RL35_MOUSE 60S ribosomal protein L35 RNA binding, mRNA binding, structural constituent of ribosome
S10A1_MOUSE Protein S100-A1 ATPase binding, S100 protein binding, calcium ion binding, protein homodimerization activity
SBDS_MOUSE Ribosome maturation protein SBDS Microtubule binding, rRNA binding, ribosome binding
SDF2_MOUSE Stromal cell-derived factor 2 Dolichyl-phosphate-mannose-protein mannosyltransferase activity
SERC1_MOUSE Serine incorporator 1 L-Serine transmembrane transporter activity
TIAR_MOUSE Nucleolysin TIAR AU-rich element binding, RNA binding, nucleotide binding
TRADD_MOUSE Tumor necrosis factor receptor type 1-associated DEATH domain protein Binding, bridging, death domain binding, identical protein binding, kinase binding, protein complex binding, signal transducer activity, tumor necrosis factor receptor binding
TRNT1_MOUSE CCA tRNA nucleotidyltransferase 1, mitochondrial ATP binding, ATP:3 -cytidine-cytidine-tRNA adenylyltransferase activity, CTP:3 -cytidine-tRNA cytidylyltransferase activity, CTP:tRNA cytidylyltransferase activity, nucleotide binding, tRNA binding, tRNA nucleotidyltransferase activity
VPS52_MOUSE Vacuolar protein sorting-associated protein 52 homolog Syntaxin binding
ZFYV1_MOUSE Zinc finger FYVE domain-containing protein 1 1-Phosphatidylinositol binding, metal ion binding, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding
ZWINT_MOUSE ZW10 interactor Protein N-terminus binding, protein binding
FBLN3_MOUSE EGF-containing fibulin-like extracellular matrix protein 1 Calcium ion binding, epidermal growth factor receptor binding, epidermal growth factor-activated receptor activity, growth factor activity
NDUB9_MOUSE NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NADH dehydrogenase (ubiquinone) activity
MIC10_MOUSE MICOS complex subunit Mic10 Molecular function
NPL_MOUSE N-Acetylneuraminate lyase N-Acetylneuraminate lyase activity, lyase activity
UCRI_MOUSE Cytochrome b-c1 complex subunit Rieske, mitochondrial 2 iron, 2 sulfur cluster binding, metal ion binding, oxidoreductase activity, acting on diphenols and related substances as donors, protein complex binding, ubiquinol-cytochrome c reductase activity
CD97_MOUSE CD97 antigen G-protein coupled receptor activity, calcium ion binding, signal transducer activity
WDR26_MOUSE WD repeat-containing protein 26 Molecular function
XIRP2_MOUSE Xin actin-binding repeat-containing protein 2 Actin binding, alpha-actinin binding, protein binding, zinc ion binding
DYR_MOUSE Dihydrofolate reductase NADP binding, NADPH binding, dihydrofolate reductase activity, dihydrofolic acid binding, folic acid binding, mRNA binding, methotrexate binding, oxidoreductase activity
AIMP1_MOUSE Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 GTPase binding, cytokine activity, protein homodimerization activity, tRNA binding
SYTC2_MOUSE Probable threonine–tRNA ligase 2, cytoplasmic ATP binding, RNA binding, nucleotide binding, threonine-tRNA ligase activity
RAB4B_MOUSE Ras-related protein Rab-4B GTP binding, nucleotide binding
RAB8A_MOUSE Ras-related protein Rab-8A GDP binding, GTP binding, GTPase activity, Rab GTPase binding, myosin V binding, nucleotide binding, protein binding, protein kinase binding
AT2B1_MOUSE Plasma membrane calcium-transporting ATPase 1 ATP binding, PDZ domain binding, calcium-transporting ATPase activity, calmodulin binding, hydrolase activity, metal ion binding, nucleotide binding
GNA11_MOUSE Guanine nucleotide-binding protein subunit alpha-11 G-protein beta/gamma-subunit complex binding, GTP binding, GTPase activity, alkylglycerophosphoethanolamine phosphodiesterase activity, guanyl nucleotide binding, metal ion binding, signal transducer activity, type 2A serotonin receptor binding
SUCB2_MOUSE Succinate–CoA ligase [GDP-forming] subunit beta, mitochondrial ATP binding, GDP binding, GTP binding, ligase activity, metal ion binding, nucleotide binding, protein heterodimerization activity, succinate-CoA ligase (GDP-forming) activity, succinate-semialdehyde dehydrogenase (NAD+) activity
GIPC1_MOUSE PDZ domain-containing protein GIPC1 GTPase activator activity, PDZ domain binding, actin binding, cadherin binding involved in cell-cell adhesion, myosin binding, protein homodimerization activity, receptor binding
ACPM_MOUSE Acyl carrier protein, mitochondrial Molecular function
ALG11_MOUSE GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity, transferase activity, transferase activity, transferring glycosyl groups
AN32E_MOUSE Acidic leucine-rich nuclear phosphoprotein 32 family member E Histone binding, phosphatase inhibitor activity
APOE_MOUSE Apolipoprotein E Antioxidant activity, beta-amyloid binding, cholesterol binding, cholesterol transporter activity, heparin binding, lipid transporter activity, lipoprotein particle binding, low-density lipoprotein particle receptor binding, metal chelating activity, phosphatidylcholine-sterol O-acyltransferase activator activity, phospholipid binding, protein binding, protein homodimerization activity, tau protein binding, very-low-density lipoprotein particle receptor binding
ARMC6_MOUSE Armadillo repeat-containing protein 6 Molecular function
BAP31_MOUSE B cell receptor-associated protein 31 MHC class I protein binding, protein complex binding
CC90B_MOUSE Coiled-coil domain-containing protein 90B, mitochondrial Molecular function
CCD22_MOUSE Coiled-coil domain-containing protein 22 Cullin family protein binding, protein binding
CDIPT_MOUSE CDP-diacylglycerol–inositol 3-phosphatidyltransferase CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity, alcohol binding, carbohydrate binding, diacylglycerol binding, manganese ion binding
CGAT1_MOUSE Chondroitin sulfate N-acetylgalactosaminyltransferase 1 Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity, glucuronosyltransferase activity, glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity, metal ion binding, peptidoglycan glycosyltransferase activity
CN37_MOUSE 2 ,3 -Cyclic-nucleotide 3 -phosphodiesterase 2 ,3 -Cyclic-nucleotide 3 -phosphodiesterase activity, RNA binding, cyclic nucleotide binding, hydrolase activity
CO4A2_MOUSE Collagen alpha-2(IV) chain Extracellular matrix structural constituent
CPSF6_MOUSE Cleavage and polyadenylation specificity factor subunit 6 RNA binding, mRNA binding, nucleotide binding
CRK_MOUSE Adapter molecule crk SH2 domain binding, SH3/SH2 adaptor activity, enzyme binding, ephrin receptor binding, protein binding, bridging, protein phosphorylated amino acid binding
CTBP2_MOUSE C-terminal-binding protein 2 NAD binding, chromatin binding, oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, protein homodimerization activity, retinoic acid receptor binding, transcription coactivator activity, transcription corepressor activity
DAD1_MOUSE Dolichyl-diphosphooligosaccharide–protein glycosyltransferase subunit DAD1 Dolichyl-diphosphooligosaccharide-protein glycotransferase activity, transferase activity, transferring glycosyl groups
DERL2_MOUSE Derlin-2 Molecular function
DHSO_MOUSE Sorbitol dehydrogenase D-Xylulose reductase activity, L-iditol 2-dehydrogenase activity, NAD binding, identical protein binding, zinc ion binding
DNJB4_MOUSE DnaJ homolog subfamily B member 4 Chaperone binding, unfolded protein binding
DYLT1_MOUSE Dynein light chain Tctex-type 1 G-protein beta-subunit binding, GTP-dependent protein binding, identical protein binding, motor activity
DYLT3_MOUSE Dynein light chain Tctex-type 3 Identical protein binding, motor activity
EFL1_MOUSE Elongation factor-like GTPase 1 GTP binding, GTPase activity, nucleotide binding, ribosome binding
EH1L1_MOUSE EH domain-binding protein 1-like protein 1 Molecular function
EMC8_MOUSE ER membrane protein complex subunit 8 Molecular function
ETHE1_MOUSE Persulfide dioxygenase ETHE1, mitochondrial Dioxygenase activity, iron ion binding, metal ion binding, sulfur dioxygenase activity
FKB11_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP11 FK506 binding, isomerase activity, peptidyl-prolyl cis-trans isomerase activity
FNTB_MOUSE Protein farnesyltransferase subunit beta Drug binding, farnesyltranstransferase activity, isoprenoid binding, peptide binding, protein farnesyltransferase activity, zinc ion binding
FUND2_MOUSE FUN14 domain-containing protein 2 Molecular function
GGA1_MOUSE ADP-ribosylation factor-binding protein GGA1
GGT5_MOUSE Glutathione hydrolase 5 proenzyme Gamma-glutamyltransferase activity, glutathione hydrolase activity
GINM1_MOUSE Glycoprotein integral membrane protein 1 Molecular function
GLRX5_MOUSE Glutaredoxin-related protein 5, mitochondrial 2 iron, 2 sulfur cluster binding, electron carrier activity, metal ion binding, protein disulfide oxidoreductase activity
HDAC7_MOUSE Histone deacetylase 7 14-3-3 protein binding, NAD-dependent histone deacetylase activity (H3-K14 specific), activating transcription factor binding, chromatin binding, metal ion binding, protein kinase C binding, protein kinase binding, repressing transcription factor binding, transcription corepressor activity
HEBP1_MOUSE Heme-binding protein 1 Heme binding
HIG1A_MOUSE HIG1 domain family member 1A, mitochondrial Molecular function
HOME3_MOUSE Homer protein homolog 3 G-protein coupled glutamate receptor binding, protein C-terminus binding, protein domain specific binding
HRG1_MOUSE Heme transporter HRG1 Heme transporter activity, molecular function
HS2ST_MOUSE Heparan sulfate 2-O-sulfotransferase 1 Heparan sulfate 2-O-sulfotransferase activity, transferase activity
IC1_MOUSE Plasma protease C1 inhibitor Peptidase inhibitor activity, serine-type endopeptidase inhibitor activity
IDHG1_MOUSE Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial ATP binding, NAD binding, isocitrate dehydrogenase (NAD+) activity, magnesium ion binding, oxidoreductase activity
LRN4L_MOUSE LRRN4 C-terminal-like protein Molecular function
LTOR5_MOUSE Ragulator complex protein LAMTOR5 Guanyl-nucleotide exchange factor activity, protein complex scaffold
LXN_MOUSE Latexin Enzyme inhibitor activity, heparin binding, metalloendopeptidase inhibitor activity
MA2B2_MOUSE Epididymis-specific alpha-mannosidase Alpha-mannosidase activity, carbohydrate binding, hydrolase activity, mannosidase activity, zinc ion binding
MDR1A_MOUSE Multidrug resistance protein 1A ATP binding, ATPase activity, coupled, ATPase activity, coupled to transmembrane movement of substances, ceramide-translocating ATPase activity, nucleotide binding, phosphatidylcholine-translocating ATPase activity, phosphatidylethanolamine-translocating ATPase activity, xenobiotic-transporting ATPase activity
MIC13_MOUSE MICOS complex subunit MIC13 Molecular function
MMAB_MOUSE Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial ATP binding, cob(I)yrinic acid a,c-diamide adenosyltransferase activity, nucleotide binding, transferase activity
MMSA_MOUSE Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial RNA binding, aldehyde dehydrogenase (NAD) activity, malonate-semialdehyde dehydrogenase (acetylating) activity, methylmalonate-semialdehyde dehydrogenase (acylating) activity, oxidoreductase activity
MPI_MOUSE Mannose-6-phosphate isomerase Isomerase activity, mannose-6-phosphate isomerase activity, zinc ion binding
NAGA_MOUSE N-Acetylglucosamine-6-phosphate deacetylase N-Acetylglucosamine-6-phosphate deacetylase activity, hydrolase activity, metal ion binding
NDUS4_MOUSE NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NADH dehydrogenase (ubiquinone) activity
NDUS5_MOUSE NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 Molecular function
NHLC3_MOUSE NHL repeat-containing protein 3 Molecular function
NU160_MOUSE Nuclear pore complex protein Nup160 Nucleocytoplasmic transporter activity
NUP50_MOUSE Nuclear pore complex protein Nup50 Ran GTPase binding
OAS1A_MOUSE 2 -5 -Oligoadenylate synthase 1A 2 -5 -Oligoadenylate synthetase activity, ATP binding, double-stranded RNA binding, metal ion binding, nucleotide binding, protein binding, transferase activity
PEDF_MOUSE Pigment epithelium-derived factor Serine-type endopeptidase inhibitor activity
PEX14_MOUSE Peroxisomal membrane protein PEX14 Beta-tubulin binding, microtubule binding, protein N-terminus binding, receptor binding, transcription corepressor activity
PEX19_MOUSE Peroxisomal biogenesis factor 19 ATPase binding, peroxisome membrane class-1 targeting sequence binding, protein N-terminus binding, protein binding
PIEZ1_MOUSE Piezo-type mechanosensitive ion channel component 1 Cation channel activity, mechanically-gated ion channel activity
PRAF1_MOUSE Prenylated Rab acceptor protein 1 Identical protein binding, proline-rich region binding, protein C-terminus binding
PRAF2_MOUSE PRA1 family protein 2 Molecular function
PREB_MOUSE Prolactin regulatory element-binding protein ARF guanyl-nucleotide exchange factor activity, DNA binding, GTPase binding, Rab guanyl-nucleotide exchange factor activity, Sar guanyl-nucleotide exchange factor activity, transcription factor activity, sequence-specific DNA binding
PSN1_MOUSE Presenilin-1 PDZ domain binding, aspartic-type endopeptidase activity, beta-catenin binding, cadherin binding, calcium channel activity, endopeptidase activity
RAB31_MOUSE Ras-related protein Rab-31 GDP binding, GTP binding, nucleotide binding
RDH13_MOUSE Retinol dehydrogenase 13 Oxidoreductase activity
RT11_MOUSE 28S ribosomal protein S11, mitochondrial mRNA 5 -UTR binding, small ribosomal subunit rRNA binding, structural constituent of ribosome
S2546_MOUSE Solute carrier family 25 member 46 Molecular function
S35F6_MOUSE Solute carrier family 35 member F6 Molecular function
S39AE_MOUSE Zinc transporter ZIP14 Ferrous iron transmembrane transporter activity, metal ion transmembrane transporter activity, zinc ion transmembrane transporter activity
SCFD2_MOUSE Sec1 family domain-containing protein 2 Molecular function
SSRP1_MOUSE FACT complex subunit SSRP1 DNA binding, RNA binding, chromatin binding
STX2_MOUSE Syntaxin-2 SNAP receptor activity, SNARE binding, calcium-dependent protein binding, protein dimerization activity
SYVN1_MOUSE E3 ubiquitin-protein ligase synoviolin ATPase binding, chaperone binding, ligase activity, ubiquitin protein ligase activity, ubiquitin protein ligase activity involved in ERAD pathway, ubiquitin-specific protease binding, unfolded protein binding, zinc ion binding
TENS3_MOUSE Tensin-3 Molecular function
TI8AB_MOUSE Putative mitochondrial import inner membrane translocase subunit Tim8 A-B Metal ion binding
TMX2_MOUSE Thioredoxin-related transmembrane protein 2 Molecular function
TNR12_MOUSE Tumor necrosis factor receptor superfamily member 12A Protein binding
TOIP2_MOUSE Torsin-1A-interacting protein 2 ATPase activator activity, ATPase binding
TOM5_MOUSE Mitochondrial import receptor subunit TOM5 homolog Protein transporter activity
TPC13_MOUSE Trafficking protein particle complex subunit 13 Molecular function
UBP19_MOUSE Ubiquitin carboxyl-terminal hydrolase 19 Hsp90 protein binding, Lys48-specific deubiquitinase activity, metal ion binding, thiol-dependent ubiquitin-specific protease activity, ubiquitin protein ligase binding
UFSP2_MOUSE Ufm1-specific protease 2 UFM1 hydrolase activity, cysteine-type peptidase activity, thiolester hydrolase activity
VMP1_MOUSE Vacuole membrane protein 1 Molecular function
TIMP1_MOUSE Metalloproteinase inhibitor 1 Cytokine activity, growth factor activity, metal ion binding, metalloendopeptidase inhibitor activity, protease binding
TM9S4_MOUSE Transmembrane 9 superfamily member 4 Molecular function
PSB8_MOUSE Proteasome subunit beta type-8 Endopeptidase activity, peptidase activity, threonine-type endopeptidase activity
QCR7_MOUSE Cytochrome b-c1 complex subunit 7 Ubiquinol-cytochrome c reductase activity
ADA10_MOUSE Disintegrin and metalloproteinase domain-containing protein 10 SH2 domain binding, SH3 domain binding, hydrolase activity, metal ion binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, protein homodimerization activity, protein kinase binding
KCT2_MOUSE Keratinocyte-associated transmembrane protein 2 Molecular function
NDRG2_MOUSE Protein NDRG2
YIF1B_MOUSE Protein YIF1B Molecular function
TIM8B_MOUSE Mitochondrial import inner membrane translocase subunit Tim8 B Metal ion binding
DJC24_MOUSE DnaJ homolog subfamily C member 24 ATPase activator activity, ferrous iron binding, zinc ion binding
VWA8_MOUSE von Willebrand factor A domain-containing protein 8 ATP binding, ATPase activity, nucleotide binding
FEN1_MOUSE Flap endonuclease 1 5 -3  exonuclease activity, 5 -flap endonuclease activity, DNA binding, RNA-DNA hybrid ribonuclease activity, catalytic activity, exonuclease activity, flap endonuclease activity, magnesium ion binding, manganese ion binding
TPD54_MOUSE Tumor protein D54 RNA binding
MCL1_MOUSE Induced myeloid leukemia cell differentiation protein Mcl-1 homolog BH3 domain binding, protein heterodimerization activity, protein homodimerization activity
PCBP4_MOUSE Poly(rC)-binding protein 4 DNA binding, RNA binding, mRNA 3  -UTR binding
GCR_MOUSE Glucocorticoid receptor RNA polymerase II core promoter proximal region sequence-specific DNA binding, glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity, lipid binding, metal ion binding, protein complex binding, protein dimerization activity, sequence-specific DNA binding, steroid hormone binding, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding, zinc ion binding
RT16_MOUSE 28S ribosomal protein S16, mitochondrial Structural constituent of ribosome
CD47_MOUSE Leukocyte surface antigen CD47 Protein binding, thrombospondin receptor activity
UBP24_MOUSE Ubiquitin carboxyl-terminal hydrolase 24 Peptidase activity, thiol-dependent ubiquitinyl hydrolase activity
ROMO1_MOUSE Reactive oxygen species modulator 1 Molecular function
GOT1B_MOUSE Vesicle transport protein GOT1B Signal transducer activity
OLR1_MOUSE Oxidized low-density lipoprotein receptor 1 Carbohydrate binding, low-density lipoprotein receptor activity
SRSF2_MOUSE Serine/arginine-rich splicing factor 2 RNA binding, nucleotide binding, pre-mRNA binding, protein kinase C binding
COMD2_MOUSE COMM domain-containing protein 2 Molecular function
PYGL_MOUSE Glycogen phosphorylase, liver form AMP binding, ATP binding, bile acid binding, carbohydrate binding, catalytic activity, drug binding, glycogen phosphorylase activity, nucleotide binding, protein homodimerization activity, purine nucleobase binding, pyridoxal phosphate binding, vitamin binding
NCF2_MOUSE Neutrophil cytosol factor 2 Rac GTPase binding, protein C-terminus binding, superoxide-generating NADPH oxidase activity
YIF1A_MOUSE Protein YIF1A Molecular function
PEPL1_MOUSE Probable aminopeptidase NPEPL1 Aminopeptidase activity, manganese ion binding, metalloexopeptidase activity
WWOX_MOUSE WW domain-containing oxidoreductase RNA polymerase II transcription coactivator activity, enzyme binding, oxidoreductase activity
PTH_MOUSE Probable peptidyl-tRNA hydrolase RNA binding, aminoacyl-tRNA hydrolase activity
PYRD_MOUSE Dihydroorotate dehydrogenase (quinone), mitochondrial FMN binding, dihydroorotate dehydrogenase activity, drug binding, ubiquinone binding
CTL1_MOUSE Choline transporter-like protein 1 Choline transmembrane transporter activity
LY6C1_MOUSE Lymphocyte antigen 6C1
OTU6B_MOUSE OTU domain-containing protein 6B Thiol-dependent ubiquitinyl hydrolase activity
NECT2_MOUSE Nectin-2 Cell adhesion molecule binding, identical protein binding, protein heterodimerization activity, protein homodimerization activity, receptor activity, receptor binding
TTYH2_MOUSE Protein tweety homolog 2 Chloride channel activity, molecular function
LMOD1_MOUSE Leiomodin-1 Actin binding, tropomyosin binding
UD16_MOUSE UDP-glucuronosyltransferase 1-6 Glucuronosyltransferase activity, protein heterodimerization activity, protein homodimerization activity, transferase activity, transferring hexosyl groups
MYL6B_MOUSE Myosin light chain 6B Calcium ion binding, motor activity, structural constituent of muscle

3.5. Relationship of the Quantitative Value (Normalized emPAI) per Housekeeping Gene of mMSC-ATs (P0 and P3)

The quantitative values of the proteins expressed in both mMSC-ATs (P0) and mMSC-ATs (P3) were represented with a scatter plot (y-axis = P3, x-axis = P0). The average quantitative value of P3-expressed proteins decreased to 69.4% compared to P0-expressed proteins (Atp5f1, B2m, Hprt1, Rplp1, Ppia, Rps18, Pgk1, Tfrc, Ywhaz, and Gapdh; Supplementary Figure 1). The quantitative values of Tubb5, Flnb, Tln1, Col1a1, Iqgap1, Hspa5, Flnc, Thbs1, Fn1, Prdx1, Rnh1, Col1a2, Vcl, Lcp1, and Fabp5 were higher at P0 than at P3. The quantitative value of Act2, Serponh1, Hsp90ab1, Hsp90aa1, Actbl2, Vdac1, S100a11, Anxa2, S100a6, Pgam1, argininosuccinate synthase (Ass1, which is regulated by hypoxia-inducible factor 1α (Hif1α)), Plec, Kpnb1, Gsn, Marcks, Eif5a, and Tpm4 was higher at P3 than at P0 (Figure 4).

Details are in the caption following the image
A scatter plot of the quantitative value (normalized emPAI) per housekeeping gene. A scatter plot showing correlation (R2 = 0.6102; gray band indicates “R2 = 1”) between the quantitative value of the mouse primary cultured cells (P0) and cells passaged 3 times (P3) (n = 1139). The dotted line is the regression line. The two lines indicate the 95% confidence interval. Each dot shows the abbreviated name of the protein.

We previously examined the protein components expressed by human MSC-ATs (hMSC-ATs) cultured in the clinical medium not containing FBS and hMSC-ATs cultured in DMEM containing FBS [25]. Based on the results of the protein expression analysis, the expression of TLN1, FLNC, and ASS1 was higher in hMSC-ATs cultured in DMEM containing FBS than in those cultured in the clinical culture medium. Therefore, the increased expression of Tln1, Flnc, and Ass1 protein at P3 compared with P0 is not caused by FBS. Regarding the change in the expression of Ass1, the activation level of Hif1α was considered to be higher at P0 than at P3, because the oxygen concentration is lower in vivo than in vitro [29, 30]. Therefore, the results of this study reflect not only the effect of cell division frequency but also the influence of oxygen concentration. When cultured cells are planted in a living body in a low-oxygen environment, the hypoxic response may be activated. Therefore, in order to interpret the results of this study more accurately, we must obtain data on the protein expression of MSCs cultured under hypoxic and high-oxygen conditions.

4. Conclusions

The functions of proteins classified by the GO analysis were quantified using the LC-MS/MS measurement system for the amount of proteins and components contained in primary cultured cells of mMSC-ATs and cells passaged three times. The ability of mMSC-ATs to differentiate into expression markers of cells, fat, and osteoblasts did not change, even after three passages. However, the protein expression decreased to 69.4%. The proteins whose expression levels decreased after three passages included Ass1 among the Hif-related proteins. Furthermore, it was revealed that 336 kinds of proteins are specifically expressed in primary cultured MSC-ATs. In conclusion, MSC-ATs used as therapeutic cells retained their cell properties after three passages but showed a decreased protein expression on LC-MS/MS.

Conflicts of Interest

The authors declare no conflicts of interest in association with the present study.

Authors’ Contributions

YN, SN, CS, and HN were assigned for the study design and study conducts. YN, SN, CS, TK, and HN were assigned for data collection, data analysis, and data interpretation. TK, NK, IS, MW, and JF were assigned for the provision of materials. YN, SN, and HN drafted the manuscript. YN, SN, and HN revised the content of the manuscript. All authors approved the final version of the manuscript. YN takes responsibility for the integrity of all of the data analyses.

Acknowledgments

We thank Naomi Kakazu (University of the Ryukyus) for clerical assistance and Saki Uema, Yuka Onishi, Maki Higa, Yuki Kawahira, and Saori Adaniya (University of the Ryukyus) for providing technical support. This work was supported by the Research Laboratory Center, Faculty of Medicine, and the Institute for Animal Experiments, Faculty of Medicine, University of the Ryukyus. This work was supported in part by the Japan Society for the Promotion of Science (JSPS; KAKENHI Grant numbers JP16H05404, JP16K10435, and JP18K08545), Japan Agency for Medical Research and Development, the Naito Foundation, and Okinawa Science and Technology Promotion Center (OSTC).

    Data Availability

    The data used to support the findings of this study are available from the corresponding author upon request.

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