1) Bacille Calmette-Guérin (BCG) revaccination timing is crucial for enhancing immunity, particularly in adolescents and young adults.

2) Prior Mycobacterium tuberculosis or non-tuberculous mycobacteria infections may influence the perceived efficacy of BCG revaccination.

3) Different BCG strains show varied immunogenicity, affecting the vaccine's protective potential.

4) Standardized randomized controlled trial methodologies are essential for robust and comparable BCG revaccination research outcomes.

Intervertebral disk (IVD) degeneration is a common phenomenon that affects patients with increasing prevalence in increasing age.

1. Of the 149 authors of the Clinical Practice Guidelines for Breast Cancer, edition 2022, 115 (77.2%) received personal payments from drug companies from 2016 to 2020.
2. More than 60% of personal payments were not declared by the authors, because of the less transparent COI policy of the Japanese Breast Cancer Society.
3. Nine authors undeclared personal payments summing $594 615 despite being higher than the thresholds.

• Combination therapy's efficacy: It's a vital strategy for treating complex diseases, overcoming drug resistance, and minimizing toxicity.
• Challenge of drug combination: The vast number of potential drug pairs makes exhaustive clinical testing impractical.
• Deep learning in drug combination prediction: Recent advancements use diverse deep learning architectures to predict synergistic drug combinations, addressing key challenges and suggesting future research directions.