European Journal of Immunology: Vol 42, No 7

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European Journal of Immunology

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European Journal of Immunology: Volume 42, Issue 7

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Cover Picture

Cover Picture: Eur. J. Immunol. 7'12

Editorial Board

Editorial Board: Eur. J. Immunol. 7'12

Contents

Contents: Eur. J. Immunol. 7'12

Forum

In this issue: Eur. J. Immunol. 7'12

Czech Immunological Society (CIS): Immunological “enthusiasm” that began in the 1950s and 60s

Highlights-Review

Thymocyte death by neglect: Contribution of engulfing macrophages

Human γδ T-cell responses in infection and immunotherapy: Common mechanisms, common mediators?

Commentaries

Would eating carrots protect your liver? A new role involving NKT cells for retinoic acid in hepatitis

Two SHIPs passing in the middle of the immune system

Frontline

Retinoic acid alleviates Con A-induced hepatitis and differentially regulates effector production in NKT cells

Cellular immune response

Lack of T cells in Act1-deficient mice results in elevated IgM-specific autoantibodies but reduced lupus-like disease

Avidity determines T-cell reactivity in abacavir hypersensitivity

Intra-islet proliferation of cytotoxic T lymphocytes contributes to insulitis progression

Complement regulates conventional DC-mediated NK-cell activation by inducing TGF-β1 in Gr-1+ myeloid cells

DC-derived TSLP promotes Th2 polarization in LPS-primed allergic airway inflammation

Immunity to infection

Unlike CD4+ T-cell help, CD28 costimulation is necessary for effective primary CD8+ T-cell influenza-specific immunity

CD4+ T-cell immunity after pandemic influenza vaccination cross-reacts with seasonal antigens and functionally differs from active influenza infection

Freeze-thaw lysates of Plasmodium falciparum-infected red blood cells induce differentiation of functionally competent regulatory T cells from memory T cells

Immunomodulation

Plasma-derived MHC class II+ exosomes from tumor-bearing mice suppress tumor antigen-specific immune responses

Lineage extrinsic and intrinsic control of immunoregulatory cell numbers by SHIP

Notch activation on effector T cells increases their sensitivity to Treg cell-mediated suppression through upregulation of TGF-βRII expression

IL-33 attenuates EAE by suppressing IL-17 and IFN-γ production and inducing alternatively activated macrophages

Correction(s) for this article

Corrections

Innate immunity

Enhanced FcαRI-mediated neutrophil migration towards tumour colonies in the presence of endothelial cells

NK cells are strongly activated by Lassa and Mopeia virus-infected human macrophages in vitro but do not mediate virus suppression

Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor

Molecular immunology

RNAi screen for kinases and phosphatases that play a role in antigen presentation by dendritic cells

AP-1 is involved in ICOS gene expression downstream of TCR/CD28 and cytokine receptor signaling

Deletion of the ST2 proximal promoter disrupts fibroblast-specific expression but does not reduce the amount of soluble ST2 in circulation

Clinical immunology

Evidence for BCR-ABL-dependent dysfunctions of iNKT cells from chronic myeloid leukemia patients

Phenotypic and functional characteristics of CD4+CD39+ FOXP3+ and CD4+CD39+FOXP3neg T-cell subsets in cancer patients

Invariant natural killer T cells are not affected by lysosomal storage in patients with Niemann-Pick disease type C

Defining a functionally distinct subset of human memory CD4+ T cells that are CD25POS and FOXP3NEG

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Complement regulates conventional DC-mediated NK-cell activation by inducing TGF-β1 in Gr-1⁺ myeloid cells

Unlike CD4⁺ T-cell help, CD28 costimulation is necessary for effective primary CD8⁺ T-cell influenza-specific immunity

CD4⁺ T-cell immunity after pandemic influenza vaccination cross-reacts with seasonal antigens and functionally differs from active influenza infection

Plasma-derived MHC class II⁺ exosomes from tumor-bearing mice suppress tumor antigen-specific immune responses

Phenotypic and functional characteristics of CD4⁺CD39⁺ FOXP3⁺ and CD4⁺CD39⁺FOXP3^neg T-cell subsets in cancer patients

Defining a functionally distinct subset of human memory CD4⁺ T cells that are CD25^POS and FOXP3^NEG