Journal of Diabetes

Highlights

• The incidence, prevalence, and DALYs rate of diabetes in China are at relatively high levels, with a severe and rapidly growing burden of disability, particularly prominent among males.
• Interventions should be strengthened for major factors contributing to the diabetes burden, including high fasting plasma glucose, high body mass index, air pollution, and dietary risks.

Highlights

• In middle-aged and elderly adults, poorly managed estimate glucose disposal rate (eGDR) levels are linked to an increased risk of stroke.
• As a result, controlling eGDR levels in stroke prevention measures needs additional focus.
• Furthermore, dynamic tracking of long-term eGDR changes may be able to identify those who are more likely to have a stroke early on, which could make it easier to put more focused preventive measures in place.

Highlights

• The overall prevalence of malnutrition in diabetic patients was 33% (95% CI: 0.25–0.40), and the at-risk prevalence of malnutrition was 44% (95% CI: 0.34–0.54).
• Diabetic patients with malnutrition had significantly lower levels of body mass index, albumin, hemoglobin, triglyceride, and high-density lipoprotein cholesterol, while showing an increase in glycosylated hemoglobin.
• C-reactive protein >10 mg/L, age, duration of diabetes, Wagner grades 3–5, with cardiovascular disease, and using insulin were identified as risk factors for malnutrition in diabetic patients.

Highlights

• This is the first report on health-related quality-of-life (HRQoL) decrements associated with subtypes of diabetes-related cardiovascular-renal complications in the year of occurrence and their residual impacts in subsequent years amongst 19 322 ambulatory Asian patients with type 2 diabetes (T2D) enrolled in the clinic-based Joint Asia Diabetes Evaluation (JADE) Register (2007–2018)
• The largest HRQoL decrements expressed as EuroQol five-dimensional questionnaire utility scores were observed in the year of occurrence of hemorrhagic stroke (−0.230), followed by ischemic stroke (−0.165), peripheral vascular disease (−0.117), lower extremity amputation (−0.093), chronic kidney disease (CKD) G5 without renal replacement therapy (RRT) (−0.079), congestive heart failure (−0.061) and CKD G3–G4 without RRT (−0.042)
• Residual impacts on HRQoL persisted for 2 years after occurrence of CHF or ischemic stroke, and 1 year after hemorrhagic stroke or CKD G3–G4 without RRT
• HRQoL estimates considering residual impacts of diabetes complications would improve accuracy of evaluation of cost-effectiveness of novel diabetes interventions at an individual level in an Asian setting

Highlights

• The study reports a comparative profile on prevalence and incidence of T2DM and its associated risk factors in the younger and the older individuals in 2006 and 2016.
• Prevalence of T2DM increased both in the younger (36%) and older individuals (11%) in a decade's time.
• Incidence rose by 120% in the younger individuals and 150% in the older group.
• Percentage increase in cardiometabolic risk was higher among the younger than in the older individuals.
• Obesity and family history of diabetes were the primary contributing factors for the rising prevalence in both groups.