• Issue

    Journal of Thrombosis and Haemostasis: Volume 19, Issue 4

    885-1142
    April 2021
Previous Issue|Next Issue
Export Citation(s)Download PDF(s)

ISSUE INFORMATION

Free Access

Issue Information

  • First Published: 31 March 2021

WHAT THE NEIGHBORS SAY

Free Access

What the neighbors say

  • Pages: 885-886
  • First Published: 31 March 2021

NEIGHBORHOOD WATCH

Free Access

Nanomedicines for hemorrhage control

Massimo F. Cau,  Amy W. Strilchuk,  Christian J. Kastrup, 
  • Pages: 887-891
  • First Published: 10 March 2021

REVIEW ARTICLES

Open Access

Monitoring of anticoagulation in thrombotic antiphospholipid syndrome

Hannah Cohen,  Maria Efthymiou,  Katrien M. J. Devreese, 
  • Pages: 892-908
  • First Published: 16 December 2020
Free Access

Von Willebrand disease type 2N: An update

Omid Seidizadeh,  Flora Peyvandi,  Pier Mannuccio Mannucci, 
  • Pages: 909-916
  • First Published: 26 January 2021

JTH COMMENTARY

Free Access

The carboxyl-terminal region of coagulation serine proteases: A matter of cut and change

Alessio Branchini, 
  • Pages: 917-919
  • First Published: 31 March 2021

HAEMOSTASIS

ORIGINAL ARTICLES

Free Access

Essential role of a carboxyl-terminal α-helix motif in the secretion of coagulation factor XI

Yuri Hayakawa,  Shogo Tamura,  Nobuaki Suzuki,  Koya Odaira,  Mahiru Tokoro,  Fumika Kawashima,  Fumihiko Hayakawa,  Akira Takagi,  Akira Katsumi,  Atsuo Suzuki,  Shuichi Okamoto,  Takeshi Kanematsu,  Tadashi Matsushita,  Tetsuhito Kojima, 
  • Pages: 920-930
  • First Published: 09 January 2021
Free Access

Novel bleeding risk score for patients with atrial fibrillation on oral anticoagulants, including direct oral anticoagulants

Luise Adam,  Martin Feller,  Lamprini Syrogiannouli,  Cinzia Del-Giovane,  Jacques Donzé,  Christine Baumgartner,  Daniel Segna,  Carmen Floriani,  Laurent Roten,  Urs Fischer,  Stefanie Aeschbacher,  Giorgio Moschovitis,  Jürg Schläpfer,  Dipen Shah,  Peter Amman,  Richard Kobza,  Matthias Schwenkglenks,  Michael Kühne,  Leo H. Bonati,  Jürg Beer,  Stefan Osswald,  David Conen,  Drahomir Aujesky,  Nicolas Rodondi, on behalf of the SWISS-AF Investigators , 
  • Pages: 931-940
  • First Published: 27 January 2021
Free Access

Plasminogen-induced foam cell formation by macrophages occurs through a histone 2B (H2B)-PAR1 pathway and requires integrity of clathrin-coated pits

Lahoucine Izem,  Katarzyna Bialkowska,  Elzbieta Pluskota,  Mitali Das,  Riku Das,  Marvin T. Nieman,  Edward F. Plow, 
  • Pages: 941-953
  • First Published: 25 January 2021
Open Access

Characterization of protein unable to bind von Willebrand factor in recombinant factor VIII products

Haarin Chun,  John R. Pettersson,  Svetlana A. Shestopal,  Wells W. Wu,  Ekaterina S. Marakasova,  Philip Olivares,  Stepan S. Surov,  Mikhail V. Ovanesov,  Rong-Fong Shen,  Andrey G. Sarafanov, 
  • Pages: 954-966
  • First Published: 01 February 2021
Free Access

Safety, pharmacokinetics, and pharmacodynamics of a next-generation subcutaneously administered coagulation factor IX variant, dalcinonacog alfa, in previously treated hemophilia B patients

Chur Woo You,  Seung-Beom Hong,  Suyeong Kim,  Ho-Jin Shin,  Jin Seok Kim,  Jung Woo Han,  Soo-Jeong Kim,  Do Young Kim,  Martin Lee,  Howard Levy, 
  • Pages: 967-975
  • First Published: 04 February 2021

BRIEF REPORT

Free Access

Decreased platelet surface phosphatidylserine predicts increased bleeding in patients with severe factor VIII deficiency

Stacy E. Croteau,  Andrew L. Frelinger III,  Anja J. Gerrits,  Alan D. Michelson, 
  • Pages: 976-982
  • First Published: 28 December 2020

THROMBOSIS

ORIGINAL ARTICLES

Free Access

Clinical history of cancer-associated splanchnic vein thrombosis

Emanuele Valeriani,  Marcello Di Nisio,  Nicoletta Riva,  Lucia Maria Caiano,  Ettore Porreca,  Soo-Mee Bang,  Jan Beyer-Westendorf,  Maria Teresa Sartori,  Giovanni Barillari,  Rita Santoro,  Pieter W. Kamphuisen,  Adriano Alatri,  Alessandra Malato,  Gianpaolo Vidili,  Doyeun Oh,  Sam Schulman,  Walter Ageno,  for the International Registry on Splanchnic Vein Thrombosis (IRSVT) study group , 
  • Pages: 983-991
  • First Published: 11 December 2020
Free Access

The timing of venous thromboembolism in ovarian cancer patients: A nationwide Danish cohort study

Henriette Strøm Kahr,  Ole B. Christiansen,  Signe Juul Riddersholm,  Inger L. Gade,  Christian Torp-Pedersen,  Aage Knudsen,  Ole Thorlacius-Ussing, 
  • Pages: 992-1000
  • First Published: 08 January 2021
Free Access

Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low-density lipoprotein receptor-deficient mice

Anh T. P. Ngo,  Kelley R. Jordan,  Paul A. Mueller,  Matthew W. Hagen,  Stéphanie E. Reitsma,  Cristina Puy,  Alexey S. Revenko,  Christina U. Lorentz,  Erik I. Tucker,  Quifang Cheng,  Monica T. Hinds,  Sergio Fazio,  Brett P. Monia,  David Gailani,  András Gruber,  Hagai Tavori,  Owen J. T. McCarty, 
  • Pages: 1001-1017
  • First Published: 09 January 2021
Open Access

Anti-β2-glycoprotein I and anti-prothrombin antibodies cause lupus anticoagulant through different mechanisms of action

Tessa Noordermeer,  Jessica E. Molhoek,  Roger E. G. Schutgens,  Silvie A. E. Sebastian,  Sandra Drost-Verhoef,  Annet C. W. van Wesel,  Philip G. de Groot,  Joost C. M. Meijers,  Rolf T. Urbanus, 
  • Pages: 1018-1028
  • First Published: 09 January 2021
Open Access

Effect of gender-affirming hormone use on coagulation profiles in transmen and transwomen

Luuk J.J. Scheres,  Nienke L.D. Selier,  Nienke M. Nota,  Jeske J.K. van Diemen,  Suzanne C. Cannegieter,  Martin den Heijer, 
  • Pages: 1029-1037
  • First Published: 01 February 2021
Free Access

Clinical characteristics and risk factors for symptomatic venous thromboembolism in hospitalized COVID-19 patients: A multicenter retrospective study

Jun-Ying Li,  Hong-Fei Wang,  Ping Yin,  Di Li,  Di-Le Wang,  Peng Peng,  Wei-Hua Wang,  Lan Wang,  Xiao-Wei Yuan,  Jin-Yuan Xie,  Fan Zhou,  Nian Xiong,  Feng Shao,  Chun-Xiu Wang,  Xiang Tong,  Hao Ye,  Wen-Jun Wan,  Ben-De Liu,  Wen-Zhu Li,  Qian Li,  Liang V. Tang,  Yu Hu,  Gregory Y. H. Lip,  The Thrombo-COVID-19 Collaborative , 
  • Pages: 1038-1048
  • First Published: 03 February 2021
Open Access

Consumptive coagulopathy is associated with a disturbed host response in patients with sepsis

Lonneke A. van Vught,  Fabrice Uhel,  Chao Ding,  Cees van‘t Veer,  Brendon P. Scicluna,  Hessel Peters-Sengers,  Peter M. C. Klein Klouwenberg,  Peter Nürnberg,  Olaf L. Cremer,  Marcus J. Schultz,  Tom van der Poll,  the MARS consortium , 
  • Pages: 1049-1063
  • First Published: 25 January 2021

BRIEF REPORT

Open Access

Prolonged elevation of D-dimer levels in convalescent COVID-19 patients is independent of the acute phase response

Liam Townsend,  Helen Fogarty,  Adam Dyer,  Ignacio Martin-Loeches,  Ciaran Bannan,  Parthiban Nadarajan,  Colm Bergin,  Cliona O’Farrelly,  Niall Conlon,  Nollaig M. Bourke,  Soracha E. Ward,  Mary Byrne,  Kevin Ryan,  Niamh O’Connell,  Jamie M. O’Sullivan,  Cliona Ni Cheallaigh,  James S. O’Donnell, 
  • Pages: 1064-1070
  • First Published: 15 February 2021

PLATELETS

ORIGINAL ARTICLES

Open Access

Biological stratification of clinical disease courses in childhood immune thrombocytopenia

David E. Schmidt,  Katja M. J. Heitink-Pollé,  Bart Mertens,  Leendert Porcelijn,  Rick Kapur,  C. Ellen van der Schoot,  Gestur Vidarsson,  Johanna G. van der Bom,  Marrie C. A. Bruin,  Masja de Haas, 
  • Pages: 1071-1081
  • First Published: 01 January 2021
Free Access

Platelet α-granule cargo packaging and release are affected by the luminal proteoglycan, serglycin

Harry Chanzu,  Joshua Lykins,  Subershan Wigna-Kumar,  Smita Joshi,  Irina Pokrovskaya,  Brian Storrie,  Gunnar Pejler,  Jeremy P. Wood,  Sidney W. Whiteheart, 
  • Pages: 1082-1095
  • First Published: 15 January 2021

BRIEF REPORT

Free Access

A comparative study of platelet factor 4-enhanced platelet activation assays for the diagnosis of heparin-induced thrombocytopenia

Julian G. Rubino,  Donald M. Arnold,  Theodore E. Warkentin,  James W. Smith,  John G. Kelton,  Ishac Nazy, 
  • Pages: 1096-1102
  • First Published: 02 January 2021

VASCULAR BIOLOGY

ORIGINAL ARTICLE

Open Access

PAR1 regulation of CXCL1 expression and neutrophil recruitment to the lung in mice infected with influenza A virus

Silvio Antoniak,  Kohei Tatsumi,  Clare M. Schmedes,  Grant J. Egnatz,  Alyson C. Auriemma,  Vanthana Bharathi,  Tracy Stokol,  Melinda A. Beck,  John H. Griffin,  Joseph S. Palumbo,  Nigel Mackman, 
  • Pages: 1103-1111
  • First Published: 21 December 2020

ISTH SSC COMMUNICATIONS

Free Access

Definition of haemostatic effectiveness in interventions used to treat major bleeding: Communication from the ISTH SSC Subcommittee on Control of Anticoagulation

Nakisa Khorsand,  Jan Beyer-Westendorf,  Ravi Sarode,  Sam Schulman,  Karina Meijer, 
  • Pages: 1112-1115
  • First Published: 31 March 2021
Open Access

The concept of rebalanced hemostasis in patients with liver disease: Communication from the ISTH SSC working group on hemostatic management of patients with liver disease

Ton Lisman,  Virginia Hernandez-Gea,  Maria Magnusson,  Lara Roberts,  Simon Stanworth,  Jecko Thachil,  Armando Tripodi, 
  • Pages: 1116-1122
  • First Published: 31 March 2021
Open Access

International pediatric thrombosis network to advance pediatric thrombosis research: Communication from the ISTH SSC subcommittee on pediatric and neonatal thrombosis and hemostasis

C. Heleen van Ommen,  Manuela Albisetti,  Mohir Bhatt,  Marianne Bonduel,  Brian Branchford,  Elizabeth Chalmers,  Anthony Chan,  Neil A. Goldenberg,  Susanne Holzhauer,  Paul Monagle,  Ulrike Nowak-Göttl,  Shoshana Revel-Vilk,  Gabriela Sciuccatie,  Nongnuch Sirachainan,  Christoph Male,  for the Subcommittee on Pediatric, Neonatal Thrombosis, Hemostasis , 
  • Pages: 1123-1129
  • First Published: 31 March 2021

LETTERS TO THE EDITOR

Free Access

Thrombotic thrombocytopenic purpura (TTP) response following COVID-19 infection: Implications for the ADAMTS-13–von Willebrand factor axis

Satish Maharaj,  Ruobing Xue,  Adam Rojan, 
  • Pages: 1130-1132
  • First Published: 31 December 2020
Free Access

Thrombotic thrombocytopenic purpura as the initial presentation of COVID-19

Marie-Claude Beaulieu,  Danny Sebastien Mettelus,  Benjamin Rioux-Massé,  Michèle Mahone, 
  • Pages: 1132-1134
  • First Published: 31 December 2020
Free Access

Comment on the article by Toorop et al.: “The relationship between DOAC levels and clinical outcomes: The measures tell the tale”

Enrico Brunetti,  Mario Bo, 
  • Pages: 1134-1136
  • First Published: 31 March 2021
Free Access

The relationship between DOAC levels and clinical outcomes: The measures tell the tale–Response from original authors Lijfering et al

Myrthe M. A. Toorop,  Luuk J. J. Scheres,  Willem M. Lijfering, 
  • Pages: 1136-1138
  • First Published: 31 March 2021
Free Access

Making treatment decisions in hemophilia based on available safety data

Mike Makris,  Cedric Hermans, 
  • Pages: 1138-1139
  • First Published: 31 March 2021

ANNOUNCEMENTS

Free Access

ISTH News and Updates: Join the ISTH Today

  • Pages: 1140-1142
  • First Published: 31 March 2021