The cover image is based on the article Resident training in interventional pathology: Ultrasound-guided fine-needle aspiration and rapid on site evaluation—5 years of teaching experience in a single university hospital by Torres-Rivas et al., https://doi.org/10.1111/cyt.13355

The image shows an ultrasound-guided fine needle aspiration on the left and the corresponding cytological image of the obtained sample on the right, illustrating the correlation between the procedure and its microscopic results.

Unleash your potential: Inside interventional pathology. From behind-the-scenes specialists to frontline innovators, interventional pathologists are reshaping patient care. They wield skills like fine needle aspiration, core needle biopsy, and Point-of-Care Ultrasound, enhancing precision and outcomes.

Interventional cytopathologist procedure from the FNA to the molecular result.

This paper delves into decade-long experience of interventional cytopathologists focusing on recent endeavours to ensure adequate samples not only for microscopic diagnosis but also for molecular testing, integrating next-generation sequencing technology into clinical practice.

Revolutionising diagnostic pathology: The One-Stop Model this study showcases a One-Stop Interventional Pathology approach, where pathologists handle sample collection and diagnosis in a single visit. #OneStopDiagnosis #InterventionalPathology.

This study demonstrates that adopting the ‘one nodule–one puncture–one slide’ strategy for thyroid fine-needle aspiration biopsy enhances procedural efficiency in digital workflows, leading to cost savings without compromising diagnostic accuracy.

Residency training in next generation of interventional pathologists: Ultrasound-guided fine-needle aspiration/core needle biopsy and rapid on site evaluation (U-ROSE)—Teaching experience.

The following study reveals a deficient practical training in fine needle aspiration cytology among cytopathologists through a questionnaire carried out using social media networks at an international level and how simulation-based methodologies are positioned as a standard in medical education, preserving patient safety.

This study highlights the critical role of cytotechnologists (CTs) and biomedical scientists (BMSs) in interventional cytopathology. Their contributions significantly improve diagnostic efficiency and patient outcomes, from pre-procedural steps to real-time decision-making.

Interventional cytopathologists need to know about ultrasound physics and instrumentation to produce an image that faithfully recreates the lesion discovered by the sonographer and diagnosed by the radiologist. A deep quantitative understanding of physics is not required. Knowledge of the basics of ultrasound and their clinical implications will help the interventionalist create a clear target for biopsy.

We can safely manage patients on antithrombotic therapy in the interventional pathology practice with this practical algorithm based on the new Antithrombotic Therapy Management Guidelines.

This new algorithm helps ensure safe care for patients on antithrombotic therapy undergoing interventional pathology procedures. #interventionalpathology.

This study identifies key challenges in Fine Needle Aspiration Cytology (FNAC) practice, including diagnostic inefficiencies and interprofessional gaps. Using a mixed-methods approach, it highlights the need for an interprofessional training module to enhance competencies, improve patient-centred care, and strengthen collaboration among healthcare professionals in FNAC procedures.

Validation study on the use of axillary ultrasound (AUS) combined with touch imprint cytology (TIC) of sentinel lymph nodes as an effective, low-cost alternative for axillary staging in cT2–3 N0 breast cancer in resource-limited settings.

This study highlights the impact of cold ischemic time on nucleic acid quality in cytology samples. RNA integrity is particularly sensitive to pre-fixation delays, emphasising the need for standardised protocols to optimise molecular testing reliability in clinical cytopathology.

B72.3 is a carcinoma marker with an acceptable performance but relatively low sensitivity. With its specificity, B72.3 may find use in an immunocytochemical panel for excluding benign mesothelial processes.

TFF1, TFF3, FOXA1, CA XII and TRPS1 are sensitive breast carcinoma markers. FOXA1 is the most sensitive, and TRPS1 is the most specific of these 5 markers. The expression of TFF1 in breast carcinoma effusions may be informative of survival.

This article reports a rare case of metastatic clear cell renal cell carcinoma presenting as a parotid gland mass, clinically and cytologically mimicking a primary salivary gland neoplasm. It underscores the diagnostic value of integrating cytological evaluation with clinical history and immunocytochemical profiling.