Cardiovascular Disease

5 August 2019
5 August 2019
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Table of Contents

Free Access

Diabetic outcomes: Cardiovascular outcomes with lipid modification H2D
糖尿病结局:H2D调脂治疗后的心血管结局

Norman E. Lepor, 
Free Access

Predicting, preventing, and managing cardiovascular and chronic kidney disease progression in people with type 2 diabetes: How to improve on traditional strategies
预测、预防与管理2型糖尿病患者的心血管疾病以及慢性肾病的进展:如何改进传统治疗策略

Matthew R. Weir, 
Predicting, preventing, and managing cardiovascular and chronic kidney disease progression in people with type 2 diabetes: How to improve on traditional strategies 预测、预防与管理2型糖尿病患者的心血管疾病以及慢性肾病的进展:如何改进传统治疗策略

Free Access

Cardiologists' approach to managing cardiovascular risk in patients with type 2 diabetes
心脏病专家管理2型糖尿病患者心血管风险的方法

Natalia Rocha,  Sandeep R. Das, 

Resting heart rate is associated with metabolic syndrome and predicted 10-year risk of cardiovascular disease: a cross-sectional study

Xueyan Wu,  Rui Du,  Chunyan Hu,  Di Cheng,  Lina Ma,  Mian Li,  Yu Xu,  Min Xu,  Yuhong Chen,  Donghui Li,  Yufang Bi,  Weiqing Wang,  Guang Ning,  Jieli Lu, 
Highlights

  • Resting heart rate (RHR) is associated with an increased risk of prevalent metabolic syndrome (MetS) and elevated 10-year predicted risk of atherosclerotic cardiovascular diseases.
  • The association between RHR and prevalent MetS was more prominent in individuals without known cardiometabolic risk factors for MetS.

Nocturnal ventricular arrhythmias are associated with the severity of cardiovascular autonomic neuropathy in type 2 diabetes

Chuhui Chen,  Weimin Wang,  Wen Zhou,  Jiewen Jin,  Wei Chen,  Dalong Zhu,  Yan Bi, 
Highlights

  • The incidence of ventricular arrhythmia increased with cardiovascular autonomic neuropathy (CAN) severity at night-time.
  • Nocturnal ventricular arrhythmias caused by CAN may be associated with circadian rhythm of cardiac parasympathetic nervous system damage or abnormal sympathetic reinnervation.
  • In patients with type 2 diabetes, CAN stage was independently associated with the presence of nocturnal ventricular arrhythmias.

Open Access

Detecting pioglitazone use and risk of cardiovascular events using electronic health record data in a large cohort of Chinese patients with type 2 diabetes
基于电子病历记录数据检测中国2型糖尿病患者服用吡格列酮及发生心血管事件的风险

Shumei Miao,  Xiao Dong,  Xin Zhang,  Shenqi Jing,  Xiaoliang Zhang,  Tingyu Xu,  Li Wang,  Xianglin Du,  Hua Xu,  Yun Liu, 
Detecting pioglitazone use and risk of cardiovascular events using electronic health record data in a large cohort of Chinese patients with type 2 diabetes 基于电子病历记录数据检测中国2型糖尿病患者服用吡格列酮及发生心血管事件的风险

Highlights

  • This study demonstrated that applying informatics tools to large electronic health record data could serve as an essential way to robustly and efficiently conduct clinical observational research.
  • The findings also validated, for the first time, the favorable effect of pioglitazone on the risk of myocardial infarction among type 2 diabetes (T2D) patients in China in a cohort of 71 783 T2D patients.

Free Access

Notes from the world congress on insulin resistance, diabetes, and cardiovascular disease
来自胰岛素抵抗、糖尿病与心血管疾病世界大会 (WCIRDC) 的记录

Zachary Bloomgarden,  Yehuda Handelsman, 
Open Access

Higher blood pressure predicts diabetes and enhances long-term risk of cardiovascular disease events in individuals with impaired glucose tolerance: Twenty-three-year follow-up of the Daqing diabetes prevention study

Xiaojue Li,  Jinping Wang,  Xiaoxia Shen,  Yali An,  Qiuhong Gong,  Hui Li,  Bo Zhang,  Ying Shuai,  Yanyan Chen,  Yinghua Hu,  Guangwei Li, 
Higher blood pressure predicts diabetes and enhances long-term risk of cardiovascular disease events in individuals with impaired glucose tolerance: Twenty-three-year follow-up of the Daqing diabetes prevention study 在糖耐量受损人群中高血压预测糖尿病和提高长期心血管事件的发生:大庆糖尿病预防研究23年随访结果

Highlights

  • The results of this paper is a post-hoc analysis of the original Da Qing Prevention Study.
  • The findings showed that hypertension per se not only led to a higher incidence of cardio-cerebral-vascular disease, but also increased the risk of cardiovascular disease events by accelerating the development of diabetes among subjects with impaired glucose tolerance.
  • It suggested that an individualized intervention targeting to control hypertension together with preventing the development of diabetes may favor the reduction of the diabetes-related macro-complications among the impaired glucose tolerance population with hypertension.

Linking of metabolomic biomarkers with cardiometabolic health in Chinese population
中国人群代谢组学标记物与心血管代谢健康的关联研究

Liang Sun,  Huaixing Li,  Xu Lin, 
Linking of metabolomic biomarkers with cardiometabolic health in Chinese population 中国人群代谢组学标记物与心血管代谢健康的关联研究

Highlights

  • Given the increased prevalence of and higher susceptibility to cardiometabolic diseases in the Chinese population, understanding the roles of genetic and non-genetic factors in the pathogenesis of diseases, identifying novel biomarkers for disease prediction, and eventually developing more effective intervention strategies are urgently needed.
  • “Omics”-based technologies, especially newly emerged metabolomics, have shown great potential in discovering novel biomarkers for precision health. However, there are still many challenges to be overcome.

Free Access

European Society of Cardiology 2018

Martin J. Kurian,  Peter J. Rentzepis,  Ann M. Carracher,  Kelly L. Close, 

Cardiovascular, cancer and mortality events after bariatric surgery in people with and without pre-existing diabetes: A nationwide study
既往存在或者不存在糖尿病的患者接受减肥手术 (bariatric surgery) 后的心血管、癌症以及死亡事件:一项全国性的研究

Nafeesa N. Dhalwani,  Francesco Zaccardi,  Hina Waheed,  Jemma Mytton,  Dimitris Papamargaritis,  David R. Webb,  Felicity Evison,  Richard Lilford,  Melanie J. Davies,  Kamlesh Khunti, 
Cardiovascular, cancer and mortality events after bariatric surgery in people with and without pre-existing diabetes: A nationwide study 既往存在或者不存在糖尿病的患者接受减肥手术 (bariatric surgery) 后的心血管、癌症以及死亡事件:一项全国性的研究

Highlights

  • Patients with diabetes carry a residual risk of cardiovascular, cancer, and mortality events after bariatric surgery: compared with patients without diabetes, the risk is 26%, 21%, 42%, and 61% higher for all-cause mortality, cancer, heart failure, and stroke, respectively, and double for myocardial infarction.
  • The risk of death after bariatric surgery remains higher in patients without diabetes than in subjects of same age from the general population.

Crossing family histories of diabetes and cardiovascular disease leads to unexpected outcomes in diabetic offspring
糖尿病与心血管疾病交叉家族史可使糖尿病后代出现意料之外的结果

Michel P. Hermans,  Sylvie A. Ahn,  Michel F. Rousseau, 

Highlights

  • Common family histories of diabetes mellitus and early onset coronary heart disease predispose to increased microvascular or macrovascular risk, respectively, in diabetic offspring.
  • Crossing these histories does not randomly redistribute vascular risk, because patients with dual familial burden see their macrovascular phenotype mitigated by having parental diabetes.
  • Hyperinsulinemia, dysfunctional high-density lipoproteins and lipoprotein[a] emerge from this analysis as potential mediators of inherited macrovascular risk.

Free Access

Myocardial considerations in type 2 diabetes: 2018: 2型糖尿病患者的心肌问题:2018年

Robert Chilton,  Charles Lin,  Kelly M. Gallegos,  Son Pham, 
Free Access

World congress on insulin resistance, diabetes and cardiovascular disease: 胰岛素抵抗、糖尿病以及心血管疾病世界大会

Zachary Bloomgarden,  Yehuda Handelsman, 
Free Access

Implications of cardiovascular outcome trials with injectable antidiabetic agents: 注射用抗糖尿病药物心血管转归试验的意义

Richard E. Pratley, 
Free Access

Medication-based versus target-based lipid management: 在血脂管理中以药物为基础还是以目标为基础

Sergio Fazio,  Michael D. Shapiro, 
Free Access

Childhood nutrition and cardiovascular disease risk: People in training for a plant-centered diet: 儿童营养与心血管疾病风险:以植物为中心的饮食培训

David R. Jacobs Jr,  Tian Hu, 
Open Access

Improving outcomes in patients with type 2 diabetes mellitus and chronic heart failure: New hope: 改善2型糖尿病合并慢性心力衰竭患者的预后:新的希望

Mark Kearney, 
Free Access

What and when is diabetes? A devil's advocate perspective on contemporary controversies in diabetes criteria and classification: 什么是糖尿病,  何时诊断糖尿病?对当代糖尿病标准和分类争议的看法

Paul Zimmet,  K. George Alberti, 
Free Access

Quantitative path to deep phenotyping: Possible importance of reduced hepatic insulin degradation to type 2 diabetes mellitus pathogenesis: 深度表型的定量途径:对于2型糖尿病发病机制来说减少肝脏胰岛素降解可能具有意义

Richard N. Bergman,  Francesca Piccinini,  Isaac Asare Bediako,  Morvarid Kabir,  Cathryn Kolka,  David Polidori,  Marilyn Ader,