• Issue

    ESC Heart Failure: Volume 7, Issue 6

    3259-4491
    December 2020
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Issue Information

Open Access

Issue Information

  • Pages: 3259-3260
  • First Published: 22 December 2020

Editorials

Open Access

Early initiation of SGLT2 inhibitors is important, irrespective of ejection fraction: SOLOIST-WHF in perspective

Subodh Verma,  Stefan D. Anker,  Javed Butler,  Deepak L. Bhatt, 
  • Pages: 3261-3267
  • First Published: 22 December 2020
Open Access

Embracing secondary mitral regurgitation with Carillon: past, present, and future

Mitja Lainscak,  Michael Böhm, 
  • Pages: 3268-3270
  • First Published: 22 December 2020
Open Access

New treatment options to reduce heart failure hospitalization

Zoltán Papp,  Attila Tóth, 
  • Pages: 3271-3273
  • First Published: 03 December 2020
Open Access

The (apparent) sacubitril/valsartan sex interaction in heart failure with preserved ejection fraction: not the result of relaxin effects but of BNP action?!

Thomas Bernd Dschietzig,  Giuseppe M.C. Rosano,  Stefan D. Anker, 
  • Pages: 3274-3277
  • First Published: 15 December 2020
Open Access

Transforming heart failure and cardio-oncology care during COVID-19

Valentina Bracun,  Rudolf A. de Boer, 
  • Pages: 3278-3280
  • First Published: 18 September 2020
Open Access

Secondary mitral regurgitation: reducing the leak, expanding the science

Sam Straw,  Dominik Schlosshan,  Klaus K. Witte, 
  • Pages: 3281-3284
  • First Published: 05 October 2020
Open Access

Cardiovascular prognosis: a new role for ceramides and other cardiometabolites

Jasmine M. F. Wu,  P. Christian Schulze, 
  • Pages: 3285-3287
  • First Published: 11 October 2020

Original Research Articles

Open Access

Relation between plasma ceramides and cardiovascular death in chronic heart failure: A subset analysis of the GISSI-HF trial

Giovanni Targher,  Gianluigi Lunardi,  Alessandro Mantovani,  Jennifer Meessen,  Stefano Bonapace,  Pier Luigi Temporelli,  Enrico Nicolis,  Deborah Novelli,  Antonio Conti,  Luigi Tavazzi,  Aldo Pietro Maggioni,  Roberto Latini, 
  • Pages: 3288-3297
  • First Published: 06 July 2020
Open Access

Efficacy and safety of SGLT2 inhibitors in heart failure: systematic review and meta-analysis

Javed Butler,  Muhammad Shariq Usman,  Muhammad Shahzeb Khan,  Stephen J. Greene,  Tim Friede,  Muthiah Vaduganathan,  Gerasimos Filippatos,  Andrew J. Stewart Coats,  Stefan D. Anker, 
  • Pages: 3298-3309
  • First Published: 22 December 2020

Open Access

The impact of pharmacist/physician care on quality of life in elderly heart failure patients: results of the PHARM-CHF randomized controlled trial

Martin Schulz,  Nina Griese-Mammen,  Pia M. Schumacher,  Stefan D. Anker,  Friedrich Koehler,  Christian Ruckes,  Volker Rettig-Ewen,  Rolf Wachter,  Dietmar Trenk,  Michael Böhm,  Ulrich Laufs, 
  • Pages: 3310-3319
  • First Published: 23 July 2020
Open Access

Effect of insulin on readmission for heart failure following a hospitalization for acute heart failure

Vicente Bertomeu-Gonzalez,  Lorenzo Fácila,  Patricia Palau,  Gema Miñana,  Gonzalo Núñez,  Rafael de la Espriella,  Enrique Santas,  Eduardo Núñez,  Vicent Bodí,  Francisco Javier Chorro,  Alberto Cordero,  Juan Sanchis,  Josep Lupón,  Antoni Bayés-Genís,  Julio Núñez, 
  • Pages: 3320-3328
  • First Published: 13 August 2020
Open Access

Long-term prognosis of patients treated by coronary sinus-based percutaneous annuloplasty: single centre experience

Janusz Lipiecki,  Hicham Fahrat,  Séverine Monzy,  Nicolat Caillot,  Tomasz Siminiak,  Tim Johnson,  Suzanne Vogt,  Matthew A. Stark,  Steven L. Goldberg, 
  • Pages: 3329-3335
  • First Published: 13 October 2020

Open Access

Association of transcatheter direct mitral annuloplasty with acute anatomic, haemodynamic, and clinical outcomes in severe mitral valve regurgitation

Martin Geyer,  Karsten Keller,  Efthymios Sotiriou,  Alexander R. Tamm,  Tobias F. Ruf,  Felix Kreidel,  Andres Beiras-Fernandez,  Tommaso Gori,  Eberhard Schulz,  Thomas Münzel,  Ralph Stephan von Bardeleben, 
  • Pages: 3336-3344
  • First Published: 11 September 2020
Open Access

Cardiopoietic stem cell therapy in ischaemic heart failure: long-term clinical outcomes

Jozef Bartunek,  Andre Terzic,  Beth A. Davison,  Atta Behfar,  Ricardo Sanz-Ruiz,  Wojciech Wojakowski,  Warren Sherman,  Guy R. Heyndrickx,  Marco Metra,  Gerasimos S. Filippatos,  Scott A. Waldman,  John R. Teerlink,  Timothy D. Henry,  Bernard J. Gersh,  Roger Hajjar,  Michal Tendera,  Stefanie Senger,  Gad Cotter,  Thomas J. Povsic,  William Wijns,  for the CHART Program , 
  • Pages: 3345-3354
  • First Published: 23 October 2020
Open Access

Relationship between duration of heart failure, patient characteristics, outcomes, and effect of therapy in PARADIGM-HF

Su E. Yeoh,  Pooja Dewan,  Akshay S. Desai,  Scott D. Solomon,  Jean L. Rouleau,  Marty Lefkowitz,  Adel Rizkala,  Karl Swedberg,  Michael R. Zile,  Pardeep S. Jhund,  Milton Packer,  John J.V. McMurray, 
  • Pages: 3355-3364
  • First Published: 19 October 2020
Open Access

10 year trends in hospitalization rates due to heart failure and related in-hospital mortality in Poland (2010–2019)

Radosław Sierpiński,  Justyna M. Sokolska,  Tomasz Suchocki,  Beata Koń,  Filip Urbański,  Marcin Kruk,  Mateusz Sokolski,  Piotr Ponikowski,  Ewa A. Jankowska, 
  • Pages: 3365-3373
  • First Published: 22 October 2020
Open Access

Lateral left ventricular lead position is superior to posterior position in long-term outcome of patients who underwent cardiac resynchronization therapy

Anett Behon,  Walter Richard Schwertner,  Eperke Dóra Merkel,  Attila Kovács,  Bálint Károly Lakatos,  Endre Zima,  László Gellér,  Valentina Kutyifa,  Annamária Kosztin,  Béla Merkely, 
  • Pages: 3374-3382
  • First Published: 22 October 2020
Open Access

Individual patient data meta-analysis of the effects of the CARILLON® mitral contour system

Francesco Giallauria,  Anna Di Lorenzo,  Alessandro Parlato,  Crescenzo Testa,  Emanuele Bobbio,  Carlo Vigorito,  Andrew J. Stewart Coats, 
  • Pages: 3383-3391
  • First Published: 22 December 2020

Open Access

Ferric carboxymaltose for the treatment of iron-deficient heart failure patients: a systematic review and meta-analysis

Muhammad Shahzeb Khan,  Muhammad Shariq Usman,  Stephan von Haehling,  Wolfram Doehner,  Andrew J. Stewart Coats, 
  • Pages: 3392-3400
  • First Published: 22 December 2020

Short Communications

Open Access

Early benefits of empagliflozin in patients with or without heart failure: findings from EMPA-REG OUTCOME

Pierpaolo Pellicori,  Anne Pernille Ofstad,  David Fitchett,  Cordula Zeller,  Christoph Wanner,  Jyothis George,  Bernard Zinman,  Martina Brueckmann,  JoAnn Lindenfeld, 
  • Pages: 3401-3407
  • First Published: 11 September 2020
Open Access

Distribution, infrastructure, and expertise of heart failure and cardio-oncology clinics in a developing network: temporal evolution and challenges during the coronavirus disease 2019 pandemic

The Taskforce of the Hellenic Heart Failure Clinics Network , 
  • Pages: 3408-3413
  • First Published: 07 October 2020

Editorials

Open Access

Clinical problems of patients with cachexia due to chronic illness: a congress report

Sara Hadzibegovic,  Philipp Sikorski,  Sophia K. Potthoff,  Jochen Springer,  Alessia Lena,  Markus S. Anker, 
  • Pages: 3414-3420
  • First Published: 04 October 2020
Open Access

ESC Heart Failure increases its impact factor

Markus S. Anker,  Zoltán Papp,  Gábor Földes,  Stephan von Haehling, 
  • Pages: 3421-3426
  • First Published: 28 October 2020

Reviews

Open Access

Frailty and the risk of all-cause mortality and hospitalization in chronic heart failure: a meta-analysis

Izabella Uchmanowicz,  Christopher S. Lee,  Cristiana Vitale,  Stanisław Manulik,  Quin E. Denfeld,  Bartosz Uchmanowicz,  Joanna Rosińczuk,  Marcin Drozd,  Joanna Jaroch,  Ewa A. Jankowska, 
  • Pages: 3427-3437
  • First Published: 21 September 2020
Open Access

Non-insulin antihyperglycaemic drugs and heart failure: an overview of current evidence from randomized controlled trials

Gianluigi Savarese,  Benedikt Schrage,  Francesco Cosentino,  Lars H. Lund,  Giuseppe M.C. Rosano,  Petar Seferovic,  Javed Butler, 
  • Pages: 3438-3451
  • First Published: 10 September 2020

Open Access

Dying to know: prognosis communication in heart failure

Casey E. Cavanagh,  Lindsey Rosman,  Erica S. Spatz,  Terri Fried,  Parul U. Gandhi,  Richard J. Soucier,  Matthew M. Burg, 
  • Pages: 3452-3463
  • First Published: 24 September 2020
Open Access

Crosstalk between coronavirus disease 2019 and cardiovascular disease and its treatment

Qing Ye,  Dezhao Lu,  Shiqiang Shang,  Junfen Fu,  Fangqi Gong,  Qiang Shu,  Jianhua Mao, 
  • Pages: 3464-3472
  • First Published: 16 September 2020
Open Access

Foetal haemodynamic response to anaemia

Keooudone Thammavong,  Suchaya Luewan,  Phudit Jatavan,  Theera Tongsong, 
  • Pages: 3473-3482
  • First Published: 10 September 2020
Open Access

The overlooked chamber in coronavirus disease 2019

Yunshan Cao,  Min Zhang,  Yanqing Guo,  Yan Zhang, 
  • Pages: 3483-3486
  • First Published: 16 September 2020
Open Access

Effect of sacubitril/valsartan on renal function: a systematic review and meta-analysis of randomized controlled trials

Francesco Spannella,  Federico Giulietti,  Andrea Filipponi,  Riccardo Sarzani, 
  • Pages: 3487-3496
  • First Published: 22 September 2020
Open Access

The role and molecular mechanism of FoxO1 in mediating cardiac hypertrophy

Wei Yu,  Chunjuan Chen,  Jidong Cheng, 
  • Pages: 3497-3504
  • First Published: 22 October 2020
Open Access

Heart failure in the last year: progress and perspective

Daniela Tomasoni,  Marianna Adamo,  Markus S. Anker,  Stephan von Haehling,  Andrew J. S. Coats,  Marco Metra, 
  • Pages: 3505-3530
  • First Published: 05 December 2020

Original Research Articles

Open Access

Clinical effects of cardiac contractility modulation in heart failure with mildly reduced systolic function

Carsten Tschöpe,  Javed Butler,  Dimitrios Farmakis,  Deborah Morley,  Ishu Rao,  Gerasimos Filippatos, 
  • Pages: 3531-3535
  • First Published: 03 December 2020
Open Access

Elevated plasma endothelin-1 is related to low natriuresis, clinical signs of congestion, and poor outcome in acute heart failure

Robert Zymliński,  Radosław Sierpiński,  Marco Metra,  Gad Cotter,  Mateusz Sokolski,  Paweł Siwołowski,  Mateusz Garus,  Piotr Gajewski,  Joanna Tryba,  Maria Samorek,  Ewa A. Jankowska,  Jan Biegus,  Piotr Ponikowski, 
  • Pages: 3536-3544
  • First Published: 16 October 2020
Open Access

Associations of region-specific visceral adiposity with subclinical atrial dysfunction and outcomes of heart failure

Bo-Han Huang,  Shun-Chuan Chang,  Chun-Ho Yun,  Kuo-Tzu Sung,  Yau-Huei Lai,  Chi-In Lo,  Wen-Hung Huang,  Shih-Chieh Chien,  Lawrence Yu-Min Liu,  Ta-Chuan Hung,  Jen-Yuan Kuo,  Jiun-Lu Lin,  Bernard Bulwer,  Charles Jia-Yin Hou,  Ying-Ju Chen,  Cheng-Huang Su,  Hung-I Yeh,  Chung-Lieh Hung, 
  • Pages: 3545-3560
  • First Published: 28 October 2020
Open Access

Association of rs2070600 in advanced glycosylation end-product specific receptor with prognosis of heart failure

Shiyang Li,  Dong Hu,  Senlin Hu,  Yang Sun,  Ying Zhang,  Huihui Li,  Yanghui Chen,  Hao Liu,  Guanglin Cui,  Dao Wen Wang, 
  • Pages: 3561-3572
  • First Published: 10 September 2020
Open Access

The effect of transfusion of blood products on ventricular assist device support outcomes

Supriya Shore,  Thomas C. Hanff,  Jeremy A. Mazurek,  Matthew Seigerman,  Robert Zhang,  Edward W. Grandin,  Esther Vorovich,  Paul Mather,  Caroline Olt,  Jessica Howard,  Joyce Wald,  Michael A. Acker,  Lee R. Goldberg,  Pavan Atluri,  Kenneth B. Margulies,  J. Eduardo Rame,  Edo Y. Birati, 
  • Pages: 3573-3581
  • First Published: 14 October 2020
Open Access

Cost-effectiveness of adding dapagliflozin to standard treatment for heart failure with reduced ejection fraction patients in China

Younan Yao,  Rongcheng Zhang,  Tao An,  Xinke Zhao,  Jian Zhang, 
  • Pages: 3582-3592
  • First Published: 27 October 2020
Open Access

Elevation of high-sensitivity cardiac troponin T and left ventricular remodelling in hypertrophic cardiomyopathy

Toru Kubo,  Yuri Ochi,  Yuichi Baba,  Kenta Sugiura,  Asa Takahashi,  Takayoshi Hirota,  Shigeo Yamanaka,  Naohito Yamasaki,  Yoshinori L. Doi,  Hiroaki Kitaoka, 
  • Pages: 3593-3600
  • First Published: 12 October 2020
Open Access

Atrial fibrillation, anticoagulation management and risk of stroke in the Cardiomyopathy/Myocarditis registry of the EURObservational Research Programme of the European Society of Cardiology

Katarzyna Mizia-Stec,  Alida L.P. Caforio,  Philippe Charron,  Juan R. Gimeno,  Perry Elliott,  Juan Pablo Kaski,  Aldo P. Maggioni,  Luigi Tavazzi,  Angelos G. Rigopoulos,  Cecile Laroche,  Attila Frigy,  Elisabetta Zachara,  Maria Luisa Pena-Pena,  Akinsanya Olusegun-Joseph,  Yigal Pinto,  Simone Sala,  Fabrizio Drago,  Olga Blagova,  Elena Reznik,  Michał Tendera, 
  • Pages: 3601-3609
  • First Published: 17 September 2020
Open Access

Antidepressant treatment in patients following acute coronary syndromes: a systematic review and Bayesian meta-analysis

Romy Sweda,  George C.M. Siontis,  Adriani Nikolakopoulou,  Stephan Windecker,  Thomas Pilgrim, 
  • Pages: 3610-3620
  • First Published: 16 September 2020
Open Access

Swollen heart in COVID-19 patients who progress to critical illness: a perspective from echo-cardiologists

Yingxian Liu,  Jinjie Xie,  Peng Gao,  Ran Tian,  Hao Qian,  Fan Guo,  Xiaowei Yan,  Yanjun Song,  Wei Chen,  Ligang Fang,  Wei Wu,  Shuyang Zhang, 
  • Pages: 3621-3632
  • First Published: 25 September 2020
Open Access

Implementation of sacubitril/valsartan in Sweden: clinical characteristics, titration patterns, and determinants

Michael Fu,  Ola Vedin,  Bodil Svennblad,  Erik Lampa,  Daniel Johansson,  Ulf Dahlström,  Krister Lindmark,  Peter Vasko,  Anna Lundberg,  Madlaina Costa-Scharplatz,  Lars H. Lund, 
  • Pages: 3633-3643
  • First Published: 03 September 2020
Open Access

Clinical characteristics and long-term outcomes of peripartum takotsubo cardiomyopathy and peripartum cardiomyopathy

Dong-Yeon Kim,  So Ree Kim,  Sung-Ji Park,  Jeong-Hun Seo,  Eun Kyoung Kim,  Jeong Hoon Yang,  Sung-A Chang,  Jin-Oh Choi,  Sang-Chol Lee,  Seung Woo Park, 
  • Pages: 3644-3652
  • First Published: 08 September 2020
Open Access

Nationwide trends in incidence, healthcare utilization, and mortality in hospitalized heart failure patients in Taiwan

Tzung-Dau Wang,  Shih-Tsung Huang,  Chen-Yu Wang,  Fang-Ju Lin,  Ho-Min Chen,  Fei-Yuan Hsiao, 
  • Pages: 3653-3666
  • First Published: 13 September 2020
Open Access

Why is the clinical response to cardiac resynchronization better in LBBB patients?

Jiří Kvasnička,  Aleš Havlíček,  Jan Bělohlávek,  Jan Večeřa,  Eva Čermáková, 
  • Pages: 3667-3675
  • First Published: 18 September 2020
Open Access

HEllenic Registry on Myocarditis SyndromES on behalf of Hellenic Heart Failure Association: The HERMES-HF Registry

Stamatis Adamopoulos,  Dimitrios Miliopoulos,  Apostolis Karavidas,  Maria Nikolaou,  George Lazaros,  Angeliki Gkouziouta,  Athanassios Manginas,  George Sevastos,  Haralambos Karvounis,  Theodoros D. Karamitsos,  George Hahalis,  Marianna Leopoulou,  Konstantinos Grigoriou,  Despoina Balta,  Catherine C. Avgeropoulou,  Alexandros Kasiakogias,  Ioannis Mantas,  Nikolaos Daskalopoulos,  Dimitrios Varvarousis,  Fragiskos I. Parthenakis,  Alexandros P. Patrianakos,  Sotirios Patsilinakos,  Stavros Karanikas,  Stavros V. Konstantinides,  Dimitrios N. Tziakas,  Nikolaos Kouvelas,  Paraskevi Ntoliou,  Athanasios J. Manolis,  Pavlos Tsinivizov,  Efstathios K. Iliodromitis,  Agathi-Rosa Vrettou,  Stavros N. Kakouros,  Alexandros Douras,  Nikoleta Mpaka,  Pantelis Makridis,  Eleni Karapatsoudi,  Neofytos Papoulidis,  Antonios Sideris,  John T. Parissis,  Filippos Triposkiadis,  Athanasios Trikas,  Gerasimos Filippatos, 
  • Pages: 3676-3684
  • First Published: 16 September 2020
Open Access

Identification of physiologic treatment targets with favourable haemodynamic consequences in heart failure with preserved ejection fraction

David M. Kaye,  Melissa Byrne,  Justin Mariani,  Shane Nanayakkara,  Daniel Burkhoff, 
  • Pages: 3685-3693
  • First Published: 09 September 2020
Open Access

Left ventricular dysfunction in atrial fibrillation and heart failure risk

Jen-Yuan Kuo,  Sheng-Hsiung Chang,  Kuo-Tzu Sung,  Po-Ching Chi,  Jo-Nan Liao,  Tze-Fan Chao,  Cheng-Huang Su,  Hung-I Yeh,  Chung-Lieh Hung, 
  • Pages: 3694-3706
  • First Published: 15 September 2020
Open Access

Metabolomic signatures of cardiac remodelling and heart failure risk in the community

Charlotte Andersson,  Chunyu Liu,  Susan Cheng,  Thomas J. Wang,  Robert E. Gerszten,  Martin G. Larson,  Ramachandran S. Vasan, 
  • Pages: 3707-3715
  • First Published: 10 September 2020
Open Access

Multi-modality machine learning approach for risk stratification in heart failure with left ventricular ejection fraction ≤ 45%

Gary Tse,  Jiandong Zhou,  Samuel Won Dong Woo,  Ching Ho Ko,  Rachel Wing Chuen Lai,  Tong Liu,  Yingzhi Liu,  Keith Sai Kit Leung,  Andrew Li,  Sharen Lee,  Ka Hou Christien Li,  Ishan Lakhani,  Qingpeng Zhang, 
  • Pages: 3716-3725
  • First Published: 23 October 2020
Open Access

Subclinical cardiac dysfunction in obesity patients is linked to autonomic dysfunction: findings from the CARDIOBESE study

Sanne M. Snelder,  Lotte E. de Groot-de Laat,  L. Ulas Biter,  Manuel Castro Cabezas,  Nadine Pouw,  Erwin Birnie,  Bianca M. Boxma-de Klerk,  René A. Klaassen,  Felix Zijlstra,  Bas M. van Dalen, 
  • Pages: 3726-3737
  • First Published: 09 September 2020
Open Access

Hepatocyte growth factor predicts failure of Fontan circulation

Takuro Kojima,  Moe Taki,  Koichi Toda,  Shota Muraji,  Shigeki Yoshiba,  Toshiki Kobayshi,  Naokata Sumitomo, 
  • Pages: 3738-3744
  • First Published: 10 September 2020
Open Access

Incidence of congestive heart failure in rheumatoid arthritis: a review of literature and meta-regression analysis

Yaser Khalid,  Neethi Dasu,  Ankit Shah,  Keith Brown,  Alan Kaell,  Adam Levine,  Kirti Dasu,  Albert Raminfard, 
  • Pages: 3745-3753
  • First Published: 07 October 2020
Open Access

A 3 year post-intervention follow-up on mortality in advanced heart failure (EVITA vitamin D supplementation trial)

Armin Zittermann,  Jana B. Ernst,  Sylvana Prokop,  Uwe Fuchs,  Heiner K. Berthold,  Ioanna Gouni-Berthold,  Jan F. Gummert,  Stefan Pilz, 
  • Pages: 3754-3761
  • First Published: 11 September 2020
Open Access

Improved 30 day heart failure rehospitalization prediction through the addition of device-measured parameters

Jason R. Brown,  Alvaro Alonso,  Sula Mazimba,  Eduardo N. Warman,  Kenneth C. Bilchick, 
  • Pages: 3762-3771
  • First Published: 13 September 2020
Open Access

Fatal lymphocytic cardiac damage in coronavirus disease 2019 (COVID-19): autopsy reveals a ferroptosis signature

Werner Jacobs,  Martin Lammens,  Annelies Kerckhofs,  Evy Voets,  Emily Van San,  Samya Van Coillie,  Cédric Peleman,  Matthias Mergeay,  Sabriya Sirimsi,  Veerle Matheeussen,  Hilde Jansens,  Ingrid Baar,  Tom Vanden Berghe,  Philippe G. Jorens, 
  • Pages: 3772-3781
  • First Published: 22 September 2020
Open Access

Intensity level and cardiorespiratory responses to Baduanjin exercise in patients with chronic heart failure

Xiankun Chen,  Gaetano Marrone,  Thomas P. Olson,  Cecilia Stålsby Lundborg,  Huiying Zhu,  Zehuai Wen,  Weihui Lu,  Wei Jiang, 
  • Pages: 3782-3791
  • First Published: 09 September 2020
Open Access

Renal function dynamics following co-administration of sacubitril/valsartan and empagliflozin in patients with heart failure and type 2 diabetes

Rafael de la Espriella,  Antoni Bayés-Genís,  Herminio Morillas,  Rafael Bravo,  Verónica Vidal,  Eduardo Núñez,  Enrique Santas,  Gema Miñana,  Juan Sanchis,  Lorenzo Fácila,  Francisco Torres,  Jose Luis Górriz,  Alfonso Valle,  Julio Núñez, 
  • Pages: 3792-3800
  • First Published: 22 September 2020
Open Access

Clinical implication of pulmonary hospitalization in heart failure with preserved ejection fraction: from the TOPCAT

Bin Dong,  Xin He,  Ruicong Xue,  Yili Chen,  Jingjing Zhao,  Wengen Zhu,  Weihao Liang,  Zexuan Wu,  Dexi Wu,  Huiling Huang,  Yuanyuan Zhou,  Yugang Dong,  Chen Liu, 
  • Pages: 3801-3809
  • First Published: 16 September 2020

Open Access

Impact of right ventricular contractile reserve during low-load exercise on exercise intolerance in heart failure

Masaki Kinoshita,  Katsuji Inoue,  Haruhiko Higashi,  Yusuke Akazawa,  Yasuhiro Sasaki,  Akira Fujii,  Teruyoshi Uetani,  Shinji Inaba,  Jun Aono,  Takayuki Nagai,  Kazuhisa Nishimura,  Shuntaro Ikeda,  Osamu Yamaguchi, 
  • Pages: 3810-3820
  • First Published: 13 September 2020
Open Access

Relative impact of bleedings over ischaemic events in patients with heart failure: insights from the CARDIONOR registry

Gilles Lemesle,  Sandro Ninni,  Pascal de Groote,  Guillaume Schurtz,  Nicolas Lamblin,  Christophe Bauters, 
  • Pages: 3821-3829
  • First Published: 11 September 2020
Open Access

Distinct clinical phenotypes of congestion in acute heart failure: characteristics, treatment response, and outcomes

Justyna Maria Sokolska,  Mateusz Sokolski,  Robert Zymliński,  Jan Biegus,  Paweł Siwołowski,  Sylwia Nawrocka-Millward,  Katarzyna Swoboda,  Piotr Gajewski,  Ewa Anita Jankowska,  Waldemar Banasiak,  Piotr Ponikowski, 
  • Pages: 3830-3840
  • First Published: 10 September 2020
Open Access

Efficacy and safety of sacubitril-valsartan in heart failure: a meta-analysis of randomized controlled trials

Hongzhou Zhang,  Tieqiu Huang,  Wen Shen,  Xiuxiu Xu,  Pingping Yang,  Dan Zhu,  Haiyang Fang,  Hongbing Wan,  Tao Wu,  Yanqing Wu,  Qinghua Wu, 
  • Pages: 3841-3850
  • First Published: 25 September 2020
Open Access

A case-crossover study on the effect of short-term exposure to moderate levels of air pollution on the risk of heart failure

Ariane Huschmann,  Marius Rasche,  Peter Schlattmann,  Otto W. Witte,  Matthias Schwab,  P. Christian Schulze,  Florian Rakers, 
  • Pages: 3851-3858
  • First Published: 13 September 2020
Open Access

Effect of disease-modifying agents and their association with mortality in multi-morbid patients with heart failure with reduced ejection fraction

Sam Straw,  Melanie McGinlay,  Samuel D. Relton,  Aaron O. Koshy,  John Gierula,  Maria F. Paton,  Michael Drozd,  Judith E Lowry,  Charlotte Cole,  Richard M Cubbon,  Klaus K. Witte,  Mark T. Kearney, 
  • Pages: 3859-3870
  • First Published: 13 September 2020
Open Access

Epidemiology of heart failure: Study of Heart failure in the Australian Primary carE setting (SHAPE)

Danny Liew,  Ralph G. Audehm,  Deepak Haikerwal,  Peter Piazza,  A. Munro Neville,  Kevin Lim,  Richard W. Parsons,  Andrew P. Sindone, 
  • Pages: 3871-3880
  • First Published: 09 September 2020
Open Access

Qishen Yiqi dripping pills for chronic ischaemic heart failure: results of the CACT-IHF randomized clinical trial

Jingyuan Mao,  Jian Zhang,  Carolyn S.P. Lam,  Mingjun Zhu,  Chen Yao,  Shutao Chen,  Zhongyong Liu,  Fengrong Wang,  Yonggang Wang,  Xiaohua Dai,  Tianfu Niu,  Dongqing An,  Yang Miao,  Tao Xu,  Bo Dong,  Xiaofeng Ma,  Fengru Zhang,  Xiaolong Wang,  Ruihong Fan,  Yingqiang Zhao,  Tiemin Jiang,  Yuhui Zhang,  Xianliang Wang,  Yazhu Hou,  Zhiqiang Zhao,  Quan Su,  Junhua Zhang,  Baohe Wang,  Boli Zhang, 
  • Pages: 3881-3890
  • First Published: 21 September 2020
Open Access

MitraClip implantation followed by insertion of a left ventricular assist device in patients with advanced heart failure

Michael M. Kreusser,  Sonja Hamed,  Andreas Weber,  Bastian Schmack,  Martin J. Volz,  Nicolas A. Geis,  Leonie Grossekettler,  Sven T. Pleger,  Arjang Ruhparwar,  Hugo A. Katus,  Philip W. Raake, 
  • Pages: 3891-3900
  • First Published: 26 October 2020
Open Access

Non-severe aortic regurgitation increases short-term mortality in acute heart failure with preserved ejection fraction

Tamila Abdurashidova,  Pierre Monney,  Georgios Tzimas,  Nisha Soborun,  Julien Regamey,  Aurelien Daux,  Nicolas Barras,  Matthias Kirsch,  Martin Müller,  Roger Hullin, 
  • Pages: 3901-3909
  • First Published: 07 October 2020
Open Access

Cost-effectiveness of empagliflozin in the UK in an EMPA-REG OUTCOME subgroup with type 2 diabetes and heart failure

Odette S. Reifsnider,  Anuraag R. Kansal,  Jennifer Franke,  Joseph Lee,  Jyothis T. George,  Martina Brueckmann,  Stefan Kaspers,  Sarah B. Brand,  Anastasia Ustyugova,  Stephan Linden,  Matthew Stargardter,  Nikco Hau, 
  • Pages: 3910-3918
  • First Published: 10 September 2020
Open Access

Heart failure from ATTRwt amyloid cardiomyopathy is associated with poor prognosis

Florian Kocher,  Alex Kaser,  Felix Escher,  Jacob Doerler,  Marc-Michael Zaruba,  Moritz Messner,  Christine Mussner-Seeber,  Agnes Mayr,  Hanno Ulmer,  Stephanie Schneiderbauer-Porod,  Christian Ebner,  Gerhard Poelzl, 
  • Pages: 3919-3928
  • First Published: 01 October 2020
Open Access

Outcomes of diuretics in rheumatic heart disease with compensated chronic heart failure: a retrospective study

Cheng Liu,  Yanxian Lai,  Tianwang Guan,  Yan Shen,  Yichao Pan,  Deping Wu, 
  • Pages: 3929-3941
  • First Published: 17 September 2020
Open Access

Disease progression in cardiac transthyretin amyloidosis is indicated by serial calculation of National Amyloidosis Centre transthyretin amyloidosis stage

Steven Law,  Aviva Petrie,  Liza Chacko,  Oliver C. Cohen,  Sriram Ravichandran,  Janet A. Gilbertson,  Dorota Rowczenio,  Ashutosh Wechalekar,  Ana Martinez-Naharro,  Helen J. Lachmann,  Carol J. Whelan,  David F. Hutt,  Philip N. Hawkins,  Marianna Fontana,  Julian D. Gillmore, 
  • Pages: 3942-3949
  • First Published: 13 September 2020
Open Access

Impact of an extended audit on identifying heart failure patients in general practice: baseline results of the OSCAR-HF pilot study

Miek Smeets,  Bert Vaes,  Bert Aertgeerts,  Willem Raat,  Joris Penders,  Jan Vercammen,  Walter Droogne,  Wilfried Mullens,  Stefan Janssens, 
  • Pages: 3950-3961
  • First Published: 24 September 2020
Open Access

Major bleeding risk with non-vitamin K antagonist oral anticoagulant vs. aspirin in heart failure: network meta-analysis

Wen-Yi Huang,  Jeffrey L. Saver,  Yi-Ling Wu,  Chun-Jen Lin,  Meng Lee,  Bruce Ovbiagele, 
  • Pages: 3962-3970
  • First Published: 13 September 2020
Open Access

Age and shock severity predict mortality in cardiac intensive care unit patients with and without heart failure

Mitchell Padkins,  Thomas Breen,  Nandan Anavekar,  Sean van Diepen,  Timothy D. Henry,  David A. Baran,  Gregory W. Barsness,  Kianoush Kashani,  David R. Holmes Jr,  Jacob C. Jentzer, 
  • Pages: 3971-3982
  • First Published: 10 September 2020
Open Access

Mineralocorticoid receptor antagonism by finerenone is sufficient to improve function in preclinical muscular dystrophy

Jeovanna Lowe,  Peter Kolkhof,  Michael J. Haupt,  Kyra K. Peczkowski,  Neha Rastogi,  J. Spencer Hauck,  Feni K. Kadakia,  Jonathan G. Zins,  Pierce C. Ciccone,  Suzanne Smart,  Peter Sandner,  Subha V. Raman,  Paul M.L. Janssen,  Jill A. Rafael-Fortney, 
  • Pages: 3983-3995
  • First Published: 18 September 2020
Open Access

Non-invasive telemonitoring improves outcomes in heart failure with reduced ejection fraction: a study in high-risk patients

Afonso Nunes-Ferreira,  João R. Agostinho,  Joana Rigueira,  Inês Aguiar-Ricardo,  Tatiana Guimarães,  Rafael Santos,  Tiago Rodrigues,  Nelson Cunha,  Pedro Silvério António,  Sara Couto Pereira,  Pedro Morais,  Mónica Mendes Pedro,  Fátima Veiga,  Fausto J. Pinto,  Dulce Brito, 
  • Pages: 3996-4004
  • First Published: 19 September 2020
Open Access

Clinical significance of spleen stiffness in patients with acute decompensated heart failure

Yuki Saito,  Naoki Matsumoto,  Yoshihiro Aizawa,  Daisuke Fukamachi,  Daisuke Kitano,  Toyama Kazuto,  Takehiro Tamaki,  Hidesato Fujito,  Akira Sezai,  Yasuo Okumura, 
  • Pages: 4005-4014
  • First Published: 13 September 2020
Open Access

Safety of transradial and transfemoral left ventricular compared with transfemoral right ventricular endomyocardial biopsy

Sebastian Göbel,  Sören Schwuchow-Thonke,  Thomas Jansen,  Susanne Karbach,  Tilman Emrich,  Tommaso Gori,  Finja Knies,  Eberhard Schulz,  Thomas Münzel,  Karsten Keller,  Philip Wenzel, 
  • Pages: 4015-4023
  • First Published: 19 September 2020
Open Access

Prognostic value of Mini Nutritional Assessment—Short Form with aortic valve stenosis following transcatheter aortic valve implantation

Shunichi Doi,  Kohei Ashikaga,  Keisuke Kida,  Mika Watanabe,  Kihei Yoneyama,  Norio Suzuki,  Shingo Kuwata,  Toshiki Kaihara,  Masashi Koga,  Kazuaki Okuyama,  Ryo Kamijima,  Yasuhiro Tanabe,  Naoya Takeichi,  Satoshi Watanabe,  Masaki Izumo,  Yuki Ishibashi,  Yoshihiro J. Akashi, 
  • Pages: 4024-4031
  • First Published: 10 September 2020
Open Access

Management of catheter ablation in arrhythmia patients during the coronavirus disease 2019 epidemic

Kaige Li,  Mu Qin,  Weifeng Jiang,  Yu Zhang,  Shaohui Wu,  Kai Xu,  Xu Liu, 
  • Pages: 4032-4039
  • First Published: 17 September 2020
Open Access

Reverse electromechanical modelling of diastolic dysfunction in spontaneous hypertensive rat after sacubitril/valsartan therapy

Yen-Ling Sung PhD,  Ting-Tse Lin MD, PhD,  Jhen-Yang Syu MS,  Hung-Jui Hsu MS,  Kai-Yuan Lin MS,  Yen-Bin Liu MD, PhD,  Shien-Fong Lin PhD, 
  • Pages: 4040-4050
  • First Published: 24 September 2020
Open Access

The prevalence, predictors, and prognosis of tricuspid regurgitation in stage B and C heart failure with preserved ejection fraction

Qing-wen Ren,  Xin-li Li,  Johnathan Fang,  Yan Chen,  Mei-Zhen Wu,  Yu-Juan Yu,  Shen-gen Liao,  Hung-Fat Tse,  Kai-Hang Yiu, 
  • Pages: 4051-4060
  • First Published: 23 September 2020
Open Access

Predictive value of heart failure with reduced versus preserved ejection fraction for outcome in pulmonary embolism

Slobodan Obradovic,  Boris Dzudovic,  Bojana Subotic,  Jovan Matijasevic,  Zorica Mladenovic,  Aleksandar Bokan,  Jadranka Trobok,  Sandra Pekovic,  Sonja Salinger-Martinovic,  Ljiljana Jovanovic,  Ljiljana Kos,  Tamara Kovacevic-Preradovic,  Maja Nikolic,  Vladimir Miloradovic,  Ana Kovacevic-Kuzmanovic,  Nenad Zec,  Natasa Markovic-Nikolic,  Ilija Srdanovic,  Zoran Gluvic,  Srdjan Kafedzic,  Sasa Pancevacki,  Aleksandar Neskovic,  Stavros Konstantinides, 
  • Pages: 4061-4070
  • First Published: 16 September 2020

Open Access

Pulmonary artery pressures and outcomes after MitraClip

Yonatan Rashi,  Dan Haberman,  Ivaylo Tonchev,  Alona Peretz,  Anna Turyan Medvedovsky,  Israel Gotsman,  Saar Minha,  Lion Poles,  Sara Shimoni,  Sorel Goland,  Gidon Y. Perlman,  Haim D. Danenberg,  Ronen Beeri,  Mony Shuvy, 
  • Pages: 4071-4079
  • First Published: 21 October 2020
Open Access

Comparison of different prediction models for the indication of implanted cardioverter defibrillator in patients with arrhythmogenic right ventricular cardiomyopathy

Giovanni Donato Aquaro,  Antonio De Luca,  Chiara Cappelletto,  Francesca Raimondi,  Francesco Bianco,  Nicoletta Botto,  Andrea Barison,  Simona Romani,  Pierluigi Lesizza,  Enrico Fabris,  Giancarlo Todiere,  Crysanthos Grigoratos,  Alessandro Pingitore,  Davide Stolfo,  Matteo Dal Ferro,  Marco Merlo,  Gianluca Di Bella,  Gianfranco Sinagra, 
  • Pages: 4080-4088
  • First Published: 23 September 2020
Open Access

Fibroblast-growth-factor-23 in heart failure with preserved ejection fraction: relation to exercise capacity and outcomes

Prathap Kanagala,  Jayanth R. Arnold,  Jamal N. Khan,  Anvesha Singh,  Gaurav S. Gulsin,  Mohamed Eltayeb,  Pankaj Gupta,  Iain B. Squire,  Gerry P. McCann,  Leong L. Ng, 
  • Pages: 4089-4099
  • First Published: 16 September 2020
Open Access

Loss of skeletal muscle mass predicts cardiac death in heart failure with a preserved ejection fraction but not heart failure with a reduced ejection fraction

Koichiro Matsumura,  Wakana Teranaka,  Hiroshi Matsumoto,  Kenichi Fujii,  Satoshi Tsujimoto,  Munemitsu Otagaki,  Shun Morishita,  Kenta Hashimoto,  Hiroki Shibutani,  Yoshihiro Yamamoto,  Ichiro Shiojima, 
  • Pages: 4100-4107
  • First Published: 23 September 2020
Open Access

Risk factors for myocardial injury in patients with coronavirus disease 2019 in China

Qin Fan,  Hongling Zhu,  Jiaxin Zhao,  Lingfang Zhuang,  Hang Zhang,  Hongyang Xie,  Ruiyan Zhang,  Juan F. Granada,  Xiaogang Xiang,  Weiguo Hu,  Xiaoxiang Yan, 
  • Pages: 4108-4117
  • First Published: 02 October 2020
Open Access

Prognostic value of D-dimer in acute myocardial infarction complicated by heart failure with preserved ejection fraction

Xiaoyuan Zhang,  Shanjie Wang,  Liping Sun,  Shaohong Fang,  Bo Yu, 
  • Pages: 4118-4125
  • First Published: 26 October 2020
Open Access

NT-pro-BNP in patients with left ventricular hypertrabeculation/non-compaction

Katharina Rapatz,  Josef Finsterer,  Astrid Voill-Glaninger,  Nastasia Wilfinger-Lutz,  Maria Winkler-Dworak,  Claudia Stöllberger, 
  • Pages: 4126-4133
  • First Published: 23 September 2020
Open Access

Clinical presentation and outcomes of peripartum cardiomyopathy in the Middle East: a cohort from seven Arab countries

Amar M. Salam,  Mohamed Badie Ahmed,  Kadhim Sulaiman,  Rajvir Singh,  Mohammed Alhashemi,  Alison S. Carr,  Alawi A. Alsheikh-Ali,  Khalid F. AlHabib,  Ibrahim Al-Zakwani,  Prashanth Panduranga,  Nidal Asaad,  Abdulla Shehab,  Wael AlMahmeed,  Jassim Al Suwaidi, 
  • Pages: 4134-4138
  • First Published: 23 September 2020
Open Access

Prediction of chronic heart failure and chronic obstructive pulmonary disease in a general population: the Tromsø study

Hasse Melbye,  Michael Stylidis,  Juan Carlos Aviles Solis,  Maria Averina,  Henrik Schirmer, 
  • Pages: 4139-4150
  • First Published: 07 October 2020
Open Access

Proteomic exploration of common pathophysiological pathways in diabetes and cardiovascular disease

John Molvin,  Amra Jujić,  Olle Melander,  Manan Pareek,  Lennart Råstam,  Ulf Lindblad,  Bledar Daka,  Margrét Leósdóttir,  Peter M. Nilsson,  Michael H. Olsen,  Martin Magnusson, 
  • Pages: 4151-4158
  • First Published: 13 October 2020
Open Access

Overexpression of endothelial β3-adrenergic receptor induces diastolic dysfunction in rats

Justine Dhot,  Marine Ferron,  Valentine Prat,  Antoine Persello,  David Roul,  David Stévant,  Damien Guijarro,  Nicolas Piriou,  Virginie Aillerie,  Angélique Erraud,  Gilles Toumaniantz,  Morteza Erfanian,  Angela Tesse,  Amandine Grabherr,  Laurent Tesson,  Séverine Menoret,  Ignacio Anegon,  Jean-Noël Trochu,  Marja Steenman,  Michel De Waard,  Bertrand Rozec,  Benjamin Lauzier,  Chantal Gauthier, 
  • Pages: 4159-4171
  • First Published: 09 October 2020
Open Access

Efficacy of exogenous atrial natriuretic peptide in patients with heart failure with preserved ejection fraction: deficiency of atrial natriuretic peptide and replacement therapy

Shingo Matsumoto,  Gaku Nakazawa,  Yohei Ohno,  Mai Ishihara,  Katsuaki Sakai,  Norihito Nakamura,  Tsutomu Murakami,  Makoto Natsumeda,  Takayuki Kabuki,  Atsushi Shibata,  Keisuke Kida,  Masaaki Konishi,  Shunsuke Ishii,  Takanori Ikeda,  Yuji Ikari, 
  • Pages: 4172-4181
  • First Published: 10 October 2020
Open Access

Reduction in heart failure hospitalization rate during coronavirus disease 19 pandemic outbreak

Paolo Severino,  Andrea D'Amato,  Andrea Saglietto,  Fabrizio D'Ascenzo,  Claudia Marini,  Marco Schiavone,  Nicolò Ghionzoli,  Filippo Pirrotta,  Francesca Troiano,  Margherita Cannillo,  Marco Mennuni,  Andrea Rognoni,  Francesco Rametta,  Alessandro Galluzzo,  Gianluca Agnes,  Fabio Infusino,  Mariateresa Pucci,  Carlo Lavalle,  Luca Cacciotti,  Paul J. Mather,  Walter Grosso Marra,  Fabrizio Ugo,  Giovanni Forleo,  Maurizio Viecca,  Nuccia Morici,  Giuseppe Patti,  Gaetano M. De Ferrari,  Alberto Palazzuoli,  Massimo Mancone,  Francesco Fedele, 
  • Pages: 4182-4188
  • First Published: 23 October 2020
Open Access

Echocardiographic abnormalities and predictors of mortality in hospitalized COVID-19 patients: the ECHOVID-19 study

Mats Christian Højbjerg Lassen,  Kristoffer Grundtvig Skaarup,  Jannie Nørgaard Lind,  Alia Saed Alhakak,  Morten Sengeløv,  Anne Bjerg Nielsen,  Caroline Espersen,  Kirstine Ravnkilde,  Raphael Hauser,  Liv Borum Schöps,  Eva Holt,  Niklas Dyrby Johansen,  Daniel Modin,  Kasper Djernæs,  Claus Graff,  Henning Bundgaard,  Christian Hassager,  Reza Jabbari,  Jørn Carlsen,  Anne-Mette Lebech,  Ole Kirk,  Uffe Bodtger,  Matias Greve Lindholm,  Gowsini Joseph,  Lothar Wiese,  Frank Vinholt Schiødt,  Ole Peter Kristiansen,  Emil Schwarz Walsted,  Olav Wendelboe Nielsen,  Birgitte Lindegaard Madsen,  Niels Tønder,  Thomas Benfield,  Klaus Nielsen Jeschke,  Charlotte Suppli Ulrik,  Filip Krag Knop,  Morten Lamberts,  Pradeesh Sivapalan,  Gunnar Gislason,  Jacob Louis Marott,  Rasmus Møgelvang,  Gorm Jensen,  Peter Schnohr,  Peter Søgaard,  Scott D. Solomon,  Kasper Iversen,  Jens Ulrik Stæhr Jensen,  Morten Schou,  Tor Biering-Sørensen, 
  • Pages: 4189-4197
  • First Published: 22 October 2020
Open Access

Influence of decompensated heart failure on cardiac acoustic biomarkers: impact on early readmissions

Julia W. Erath,  Piotr Wanczura,  Jerzy Wranicz,  Axel Linke,  Ursula Rohrer,  Daniel Scherr, 
  • Pages: 4198-4205
  • First Published: 16 October 2020
Open Access

Exploring correlates of improved depression symptoms and quality of life following tai chi exercise for patients with heart failure

Christina M. Luberto,  Charles A. Coey,  Roger B. Davis,  Peter M. Wayne,  Sydney Crute,  Gloria Y. Yeh, 
  • Pages: 4206-4212
  • First Published: 09 October 2020
Open Access

Optimal timing of echocardiography for heart failure inpatients in Japanese institutions: OPTIMAL Study

Hidekazu Tanaka,  Yosuke Nabeshima,  Tetsuji Kitano,  Sakura Nagumo,  Miki Tsujiuchi,  Mio Ebato,  Hiroyuki Mataki,  Masanori Takada,  Taichi Hayashi,  Daisuke Sato,  Yoko Miyasaka,  Keiko Araki,  Noriaki Iwahashi,  Masaaki Takeuchi,  Satoshi Nakatani,  OPTIMAL investigators , 
  • Pages: 4213-4221
  • First Published: 02 October 2020
Open Access

Short-term changes in left and right systolic function following ferric carboxymaltose: a substudy of the Myocardial-IRON trial

Enrique Santas,  Gema Miñana,  Ingrid Cardells,  Patricia Palau,  Pau Llàcer,  Lorenzo Fácila,  Luis Almenar,  Maria P. López-Lereu,  Jose V. Monmeneu,  Juan Sanchis,  Alicia M. Maceira,  Antoni Bayés-Genís,  Julio Núñez,  Myocardial-IRON Investigators , 
  • Pages: 4222-4230
  • First Published: 11 October 2020
Open Access

Endothelial dysfunction and the risk of heart failure in a community-based study: the Multi-Ethnic Study of Atherosclerosis

Johan Ärnlöv,  Yingying Sang,  Shoshana H. Ballew,  Dhananjay Vaidya,  Erin D. Michos,  David R. Jacobs Jr,  Joao Lima,  Michael G. Shlipak,  Alain G. Bertoni,  Josef Coresh,  Michael Blaha,  Wendy S. Post,  Kunihiro Matsushita, 
  • Pages: 4231-4240
  • First Published: 20 October 2020
Open Access

Accuracy of Doppler blood pressure measurement in HeartMate 3 ventricular assist device patients

Song Li,  Jennifer A. Beckman,  Nathan G. Welch,  Richard K. Cheng,  Sunny W. Rockom,  Wayne C. Levy,  Kevin D. O'Brien,  Todd F. Dardas,  Shin Lin,  Peter J. Leary,  James Kirkpatrick,  James M. McCabe,  Jason Bjelkengren,  Fanette Chassagne,  Alberto Aliseda,  Daniel Zimpfer,  Claudius Mahr, 
  • Pages: 4241-4246
  • First Published: 01 October 2020
Open Access

Critical appraisal of the instantaneous end-diastolic pulmonary arterial wedge pressures

Aristomenis Manouras,  Lars H. Lund,  László Gellér,  Anikó Ilona Nagy,  Jonas Johnson, 
  • Pages: 4247-4255
  • First Published: 06 October 2020
Open Access

Pathophysiological role of fatty acid-binding protein 4 in Asian patients with heart failure and preserved ejection fraction

Tomonari Harada,  Hiroaki Sunaga,  Hidemi Sorimachi,  Kuniko Yoshida,  Toshimitsu Kato,  Koji Kurosawa,  Takashi Nagasaka,  Norimichi Koitabashi,  Tatsuya Iso,  Masahiko Kurabayashi,  Masaru Obokata, 
  • Pages: 4256-4266
  • First Published: 02 November 2020
Open Access

Nitrates in combination with hydralazine in cardiorenal syndrome: a randomized controlled proof-of-concept study

Shir Lynn Lim,  Mihir Gandhi,  Kai Lee Woo,  Horng Ruey Chua,  Yoke Ching Lim,  David K.L. Sim,  Sheldon S.G. Lee,  Yee Leong Teoh,  Arthur Mark Richards,  Carolyn S.P. Lam, 
  • Pages: 4267-4276
  • First Published: 04 November 2020
Open Access

Prediction of worsening heart failure events and all-cause mortality using an individualized risk stratification strategy

Michael R. Zile,  Jodi Koehler,  Shantanu Sarkar,  Javed Butler, 
  • Pages: 4277-4289
  • First Published: 28 October 2020

Perspective

Open Access

Being responsible for someone else: a shared duty for parents and heart failure specialists during the COVID-19 pandemic

Massimo Mapelli, 
  • Pages: 4290-4292
  • First Published: 07 October 2020

Case Reports

Open Access

Safe application of extensive radiotherapy to a cardiac resynchronization device

Christiana Schernthaner,  Michael Kopp,  Karin Dagn,  Lukas Rettenbacher,  Lukas Weiss,  Damian Meyersburg,  Mathias-Christoph Brandt,  Uta C. Hoppe,  Bernhard Strohmer, 
  • Pages: 4293-4296
  • First Published: 11 October 2020
Open Access

Takotsubo syndrome as a complication in a critically ill COVID-19 patient

Maurizio Bottiroli,  Daniele De Caria,  Oriana Belli,  Angelo Calini,  Patrizia Andreoni,  Antonio Siragusa,  Antonella Moreo,  Enrico Ammirati,  Michele Mondino,  Roberto Fumagalli, 
  • Pages: 4297-4300
  • First Published: 04 September 2020
Open Access

The De Winter-like electrocardiogram pattern in inferior and lateral leads associated with left circumflex coronary artery occlusion

Qingxing Chen,  Tian Zou,  Yang Pang,  Yunlong Ling,  Wenqing Zhu, 
  • Pages: 4301-4304
  • First Published: 14 September 2020
Open Access

Isolated atrial amyloidosis suspected by electrophysiological voltage mapping and diagnosed by 99mTc-DPD scintigraphy

Doreen Schöppenthau,  Imke Schatka,  Alexander Berger,  Burkert Pieske,  Kathrin Hahn,  Fabian Knebel,  Felix Kleefeld,  Tobias Alexander,  Jin-Hong Gerds-Li,  Daniel Messroghli, 
  • Pages: 4305-4310
  • First Published: 04 October 2020
Open Access

Takotsubo syndrome in the same heart before and after heart transplantation

Masaki Tsuji,  Eisuke Amiya,  Chie Bujo,  Hisataka Maki,  Junichi Ishida,  Masaru Hatano,  Minoru Ono,  Issei Komuro, 
  • Pages: 4311-4314
  • First Published: 10 September 2020
Open Access

Cardiac involvement with anti-mitochondrial antibody-positive myositis mimicking cardiac sarcoidosis

Takahide Kadosaka,  Shingo Tsujinaga,  Hiroyuki Iwano,  Kiwamu Kamiya,  Azusa Nagai,  Yoshifumi Mizuguchi,  Ko Motoi,  Kazunori Omote,  Toshiyuki Nagai,  Ichiro Yabe,  Toshihisa Anzai, 
  • Pages: 4315-4319
  • First Published: 11 September 2020
Open Access

Edge-to-edge tricuspid valve repair for severe tricuspid regurgitation 20 years after cardiac transplantation

Naoki Misumida,  D. Eric Steidley,  Mackram F. Eleid, 
  • Pages: 4320-4325
  • First Published: 18 September 2020
Open Access

A combination of quinidine/mexiletine reduces arrhythmia in dilated cardiomyopathy in two patients with R814W SCN5A mutation

Joanna Zakrzewska-Koperska,  Zofia T. Bilińska,  Grażyna T. Truszkowska,  Maria Franaszczyk,  Waldemar Elikowski,  Grzegorz Warmiński,  Katarzyna Kalin,  Piotr Urbanek,  Robert Bodalski,  Michał Orczykowski,  Łukasz Szumowski,  Rafał Płoski,  Maria Bilińska, 
  • Pages: 4326-4335
  • First Published: 20 October 2020
Open Access

A valuable cardiac magnetic resonance investigation after MINOCA/takotsubo Syndrome: a case report

Snehasis Pradhan,  Nedall Zalloum,  Gresa Kciku,  Hans-Joachim Trappe, 
  • Pages: 4336-4342
  • First Published: 23 September 2020
Open Access

A rare case of severe right heart failure due to pulmonary artery lymphomatoid granulomatosis

Hongling Su,  Rong Wei,  Yichao Duan,  Zhaoxia Guo,  Aqian Wang,  Na Jiang,  Wanpeng Li,  Yan Zhu,  Yanqing Guo,  Min Zhang,  Yan Zhang,  Yunshan Cao, 
  • Pages: 4343-4347
  • First Published: 10 September 2020
Open Access

Balloon aortic valvuloplasty for urgent treatment of severe aortic stenosis during coronavirus disease 2019 pandemic: a case report

Tiziana Attisano,  Angelo Silverio,  Michele Bellino,  Carlo Tumscitz,  Fabio Felice Tarantino,  Andrea Santarelli,  Cesare Baldi,  Rodolfo Citro,  Gennaro Galasso, 
  • Pages: 4348-4352
  • First Published: 19 September 2020
Open Access

De Winter syndrome as an emergency electrocardiogram sign of ST-elevation myocardial infarction: a case report

Jianwei Yan,  Qian Wang,  Zhiliang Zhang,  Guoxiang Shi,  Jinghai Hua,  Ru Ying,  Ting Kang,  Zhenzhong Zheng,  Zeqi Zheng,  Xiaoping Peng,  Jianbing Zhu, 
  • Pages: 4353-4356
  • First Published: 26 September 2020
Open Access

Myocarditis and intramural coronary vasculitis in polyarteritis nodosa: an unusual treatable form of heart failure

Cristina Chimenti,  Maria Alfarano,  Federica Toto,  Francesca Fanisio,  Romina Verardo,  Nicola Galea,  Luciano Agati,  Andrea Frustaci, 
  • Pages: 4357-4360
  • First Published: 23 October 2020
Open Access

A rise in left atrial pressure detected by the V-LAP™ system for patients with heart failure during the coronavirus disease 2019 pandemic

Leor Perl,  Binyamin Ben Avraham,  Hana Vaknin-Assa,  Tuvia Ben Gal,  Ran Kornowski, 
  • Pages: 4361-4366
  • First Published: 23 September 2020
Open Access

Fulminant myocarditis in a patient with coronavirus disease 2019 and rapid myocardial recovery following treatment

Hawkins C. Gay,  Arjun Sinha,  Eriberto Michel,  Anthony B. Mozer,  Ashley Budd,  Matthew J. Feinstein,  Keith H. Benzuly,  Abbas Al-Qamari,  Amit A. Pawale,  Esther E. Vorovich, 
  • Pages: 4367-4370
  • First Published: 15 October 2020
Open Access

Delayed acute myocarditis and COVID-19-related multisystem inflammatory syndrome

Martin Nicol,  Lea Cacoub,  Mathilde Baudet,  Yoram Nahmani,  Patrice Cacoub,  Alain Cohen-Solal,  Patrick Henry,  Homa Adle-Biassette,  Damien Logeart, 
  • Pages: 4371-4376
  • First Published: 26 October 2020

Short Communications

Open Access

Heart failure hospitalizations and costs in ICD/CRT-D recipients following replacement or upgrade: the DECODE registry

Valerio Zacà,  Maria Lucia Narducci,  Matteo Ziacchi,  Serafina Valente,  Gemma Pelargonio,  Corrado Tomasi,  Alberto Bandini,  Gianluca Zingarini,  Vittorio Calzolari,  Attilio Del Rosso,  Giulio Boggian,  Paolo Sabbatani,  Massimo Vincenzo Bonfantino,  Maurizio Malacrida,  Mauro Biffi, 
  • Pages: 4377-4383
  • First Published: 04 September 2020
Open Access

A genetic association study of heart failure: more evidence for the role of BAG3 in idiopathic dilated cardiomyopathy

Simon de Denus,  Fannie Mottet,  Sandra Korol,  Yassamin Feroz Zada,  Sylvie Provost,  Ian Mongrain,  Géraldine Asselin,  Essaïd Oussaïd,  David Busseuil,  Guillaume Lettre,  John Rioux,  Normand Racine,  Eileen O'Meara,  Michel White,  Jean Rouleau,  Jean Claude Tardif,  Marie-Pierre Dubé, 
  • Pages: 4384-4389
  • First Published: 01 September 2020
Open Access

Impact of body mass index on surgical coronary revascularization for ischaemic heart failure: insights from STICHES

Nicholas S. Hendren,  Lin Zhong,  Ian J. Neeland,  Katherine C. Michelis,  Mark H. Drazner,  W.H. Wilson Tang,  Ambarish Pandey,  Justin L. Grodin, 
  • Pages: 4390-4393
  • First Published: 13 September 2020
Open Access

Assessment of major mental disorders in a German peripartum cardiomyopathy cohort

Tobias J. Pfeffer,  Julian Herrmann,  Dominik Berliner,  Tobias König,  Lotta Winter,  Melanie Ricke-Hoch,  Evgeni Ponimaskin,  Sven Schuchardt,  Thomas Thum,  Denise Hilfiker-Kleiner,  Johann Bauersachs,  Kai G. Kahl, 
  • Pages: 4394-4398
  • First Published: 10 September 2020
Open Access

Relative contribution of risk factors/co-morbidities to heart failure pathogenesis: interaction with ejection fraction

Grigorios Giamouzis,  Andrew Xanthopoulos,  Michail Papamichalis,  Artemis-Nantia Chroub-Papavaiou,  Aikaterini Pantziou,  Anthi Simou,  Apostolos Dimos,  Angeliki Bourazana,  John Skoularigis,  Filippos Triposkiadis, 
  • Pages: 4399-4403
  • First Published: 19 September 2020
Open Access

The role of sacubitril/valsartan in the management of cardiac resynchronization therapy non-responders: a retrospective analysis

Kyeong-Hyeon Chun,  Jaewon Oh,  Hee Tae Yu,  Chan Joo Lee,  Tae-Hoon Kim,  Jae Sun Uhm,  Hui-Nam Pak,  Moon-Hyoung Lee,  Boyoung Joung,  Seok-Min Kang, 
  • Pages: 4404-4407
  • First Published: 11 September 2020
Open Access

Surface electrocardiographic characteristics in coronavirus disease 2019: repolarization abnormalities associated with cardiac involvement

Liang Chen,  Yi Feng,  Jia Tang,  Wei Hu,  Ping Zhao,  Xiaoxiao Guo,  Ninghao Huang,  Yuwei Gu,  Linjie Hu,  Firat Duru,  Chenglong Xiong,  Mingquan Chen, 
  • Pages: 4408-4415
  • First Published: 08 September 2020
Open Access

In-hospital mortality in heart failure in Germany during the Covid-19 pandemic

Andreas Bollmann,  Sven Hohenstein,  Sebastian König,  Andreas Meier-Hellmann,  Ralf Kuhlen,  Gerhard Hindricks, 
  • Pages: 4416-4419
  • First Published: 11 September 2020
Open Access

Impact of lockdown on patients with congestive heart failure during the coronavirus disease 2019 pandemic

Frédéric Chagué,  Mathieu Boulin,  Jean-Christophe Eicher,  Florence Bichat,  Maïlis Saint Jalmes,  Amélie Cransac-Miet,  Agnès Soudry-Faure,  Nicolas Danchin,  Yves Cottin,  Marianne Zeller, 
  • Pages: 4420-4423
  • First Published: 30 September 2020
Open Access

Bedside chest ultrasound to distinguish heart failure from pneumonia-related dyspnoea in older COVID-19 patients

Arthur Hacquin,  Sophie Putot,  Jérémy Barben,  Frédéric Chagué,  Marianne Zeller,  Yves Cottin,  Patrick Manckoundia,  Alain Putot, 
  • Pages: 4424-4428
  • First Published: 13 October 2020
Open Access

Empagliflozin inhibits Na+/H+ exchanger activity in human atrial cardiomyocytes

Maximilian Trum,  Johannes Riechel,  Simon Lebek,  Steffen Pabel,  Samuel T. Sossalla,  Stephan Hirt,  Michael Arzt,  Lars S. Maier,  Stefan Wagner, 
  • Pages: 4429-4437
  • First Published: 18 September 2020
Open Access

Regional protein expression changes within the left ventricle in a mouse model of dyssynchronous and resynchronized heart failure

Hugo Nordin,  Ryo Nakagawa,  Marita Wallin,  John Pernow,  David A. Kass,  Marcus Ståhlberg, 
  • Pages: 4438-4442
  • First Published: 27 October 2020
Open Access

The effect of concomitant COVID-19 infection on outcomes in patients hospitalized with heart failure

Nikhil Chatrath,  Nandita Kaza,  Punam A. Pabari,  Kevin Fox,  Jamil Mayet,  Carys Barton,  Graham D. Cole,  Carla M. Plymen, 
  • Pages: 4443-4447
  • First Published: 11 October 2020

Study Designs

Open Access

Study design of Heart failure Events reduction with Remote Monitoring and eHealth Support (HERMeS)

Sergi Yun,  Cristina Enjuanes,  Esther Calero,  Encarnación Hidalgo,  Marta Cobo,  Pau Llàcer,  José Manuel García-Pinilla,  Álvaro González-Franco,  Julio Núñez,  José Luis Morales-Rull,  Paola Beltrán,  Cristina Delso,  Román Freixa-Pamias,  Pedro Moliner,  Xavier Corbella,  Josep Comín-Colet,  the HERMeS trial investigators group , 
  • Pages: 4448-4457
  • First Published: 17 September 2020
Open Access

Mechanisms of Diuretic Resistance Study: design and rationale

Zachary L. Cox,  James Fleming,  Juan Ivey-Miranda,  Matthew Griffin,  Devin Mahoney,  Keyanna Jackson,  Daniel Z. Hodson,  Daniel Thomas Jr,  Nicole Gomez,  Veena S. Rao,  Jeffrey M. Testani, 
  • Pages: 4458-4464
  • First Published: 06 September 2020
Open Access

Efficacy of early initiation of ivabradine treatment in patients with acute heart failure: rationale and design of SHIFT-AHF trial

Yang Su,  Teng Ma,  Zeyu Wang,  Bin Dong,  Chenhui Tai,  Hao Wang,  Fenglei Zhang,  Chunxi Yan,  Wei Chen,  Yawei Xu,  Lei Ye,  Gee Jun Tye,  Sang-Bing Ong,  Jian Zhang,  Dachun Xu, 
  • Pages: 4465-4471
  • First Published: 18 September 2020
Open Access

How do SYMPtoms and management tasks in chronic heart failure imPACT a person's life (SYMPACT)? Protocol for a mixed-methods study

Rosalynn C. Austin,  Lisette Schoonhoven,  Alison Richardson,  Paul R. Kalra,  Carl R. May, 
  • Pages: 4472-4477
  • First Published: 17 September 2020
Open Access

Stratified Treatment of Heart Failure with preserved Ejection Fraction: rationale and design of the STADIA-HFpEF trial

Mariëlle Scheffer,  Annet Driessen-Waaijer,  Nazha Hamdani,  Jochem W.D. Landzaat,  Nini H. Jonkman,  Walter J. Paulus,  Loek van Heerebeek, 
  • Pages: 4478-4487
  • First Published: 19 October 2020

Letters to the Editor

Open Access

Sarcolipin acts as a bridge between diabetes and heart failure

Peng Zhong,  Jianye Peng, 
  • Page: 4488
  • First Published: 10 September 2020
Open Access

Crosstalk between the liver and heart: revisited for prevention and treatment

Atsushi Tanaka,  Koichi Node, 
  • Pages: 4489-4490
  • First Published: 01 October 2020
Open Access

Optimal echocardiographic ramp testing during left ventricular assist device supports

Teruhiko Imamura, 
  • Page: 4491
  • First Published: 15 October 2020