Reviews

Welcome to the American Journal of Transplantation Reviews Page!


2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010

2022

Comprehensive Reviews
Immunosuppressive therapy after solid organ transplantation and the gut microbiota: Bidirectional interactions with clinical consequences

Minireviews
Body composition and the skeletal muscle compartment in liver transplantation: Turning challenges into opportunities
Examining post-donation outcomes in Hispanic/Latinx living kidney donors in the United States: A systematic review
Nanotherapeutics in transplantation: How do we get to clinical implementation?
Imlifidase for the treatment of anti-HLA antibody-mediated processes in kidney transplantation
Preclinical models versus clinical renal ischemia reperfusion injury: A systematic review based on metabolic signatures
Robotic donor hepatectomy: A major breakthrough in living donor liver transplantation

2021

Comprehensive Reviews
Challenges, highlights, and opportunities in cellular transplantation: A white paper of the current landscape
The failing kidney allograft: A review and recommendations for the care and management of a complex group of patients
Pretransplant solid organ malignancy and organ transplant candidacy: A consensus expert opinion statement
Preexisting melanoma and hematological malignancies, prognosis, and timing to solid organ transplantation: A consensus expert opinion statement
Impact of COVID‐19 in solid organ transplant recipients

Minireviews
The potential of ex vivo lung perfusion on improving organ quality and ameliorating ischemia reperfusion injury
“Time is tissue”—A minireview on the importance of donor nephrectomy, donor hepatectomy, and implantation times in kidney and liver transplantation
Microbiota and immunoregulation: A focus on regulatory B lymphocytes and transplantation
The respiratory microbiome after lung transplantation: Reflection or driver of respiratory disease?
Frailty and aging-associated syndromes in lung transplant candidates and recipients
The role of endoscopy in the small intestinal transplant recipient: A review
Normothermic kidney perfusion: An overview of protocols and strategies
Surgical considerations in infant lung transplantation: Challenges and opportunities
Alternative strategies of posttransplant influenza vaccination in adult solid organ transplant recipients

2020

Comprehensive Reviews

A comprehensive review of the impact of tacrolimus intrapatient variability on clinical outcomes in kidney transplantation
Liver transplantation for hepatocellular carcinoma: Management after the transplant

Minireviews

Applications of CRISPR technologies in transplantation

Extracellular vesicles for treatment of solid organ ischemia–reperfusion injury

Cyclosporine and COVID‐19: Risk or favorable?

When tissue is the issue: A histological review of chronic lung allograft dysfunction

Novel therapeutic opportunities afforded by plasma cell biology in transplantation

Lymphatic vessels in solid organ transplantation and immunobiology

Harnessing the microbiota for therapeutic purposes

Role of donor macrophages after heart and lung transplantation

RNA interference therapeutics in organ transplantation: The dawn of a new era

Deciphering the role of eosinophils in solid organ transplantation

Extracellular nucleotide signaling in solid organ transplantation

Outstanding questions in transplantation: Tolerance

A case for the reuse and adaptation of mechanistic computational models to study transplant immunology

Trained immunity in organ transplantation

Non‐HLA donor–recipient mismatches in kidney transplantation—A stone left unturned

 

2019

 

Comprehensive Reviews

Gynecologic cancers and solid organ transplantation

On the elusive TCR specificity of thymic regulatory T cells

Minireviews

A review of behavioral alcohol interventions for transplant candidates and recipients with alcohol‐related liver disease

Erythropoietin, a multifaceted protein with innate and adaptive immune modulatory activity

The “other” mTOR complex: New insights into mTORC2 immunobiology and their implications

Single cell immune profiling in transplantation research

Donor organ intervention before kidney transplantation: Head‐to‐head comparison of therapeutic hypothermia, machine perfusion, and donor dopamine pretreatment. What is the evidence?

The neonatal Fc receptor: Key to homeostasic control of IgG and IgG‐related biopharmaceuticals

 

2018

 

Comprehensive Reviews

Maintaining T cell tolerance of alloantigens: Lessons from animal studies

Plasma cell diseases and organ transplant: A comprehensive review

Comprehensive review of post-organ transplant hematologic cancers

Urologic malignancies in kidney transplantation

Minireviews

The relationship between pathologic lesions of active and chronic antibody‐mediated rejection in renal allografts

Polymer scaffolds for pancreatic islet transplantation — Progress and challenges

Infectious disease risks in xenotransplantation

Engineering therapuetic T cells to suppress alloimmune responses using TCRs, CARs, or BARs 

Visceral transplantation in patients with intestinal‐failure associated liver disease: Evolving indications, graft selection, and outcomes

Biologic mechanisms and clinical consequences of pregnancy alloimmunization

Reproductive health in women following abdominal organ transplant

Review: The transcripts associated with organ allograft rejection

Heterogeneity of memory B cells

Insights on the impact of diet-mediated microbiota alterations on immunity and diseases

Neuro-immune interactions in inflammation and host defense: Implications for transplantation

Innate allorecognition by monocytic cells and its role in graft rejection

Microbial metabolites and graft versus host disease

 

 

2017

 

Comprehensive Reviews

Palliative and end of life care in solid organ transplantation

Mechanical Circulatory Support in the Treatment of Advanced Heart Failure

Comprehensive Review on Colorectal Cancer and Transplant

Skin Cancers in Organ Transplant Recipients

Infection in Organ Transplantation

Chemotherapy and Transplantation: The Role of Immunosuppression in Malignancy and a Review of Antineoplastic Agents in Solid Organ Transplant Recipients

Breast Cancer and Transplantation

Minireviews

The Immunoproteasome: An Old Player With a Novel and Emerging Role in Alloimmunity

Solid Renal Masses in Transplanted Allograft Kidneys: A Closer Look at the Epidemiology and Management

Cutaneous Toxicities From Transplantation-Related Medications

The Resurgence of Xenotransplantation

Prevention of the Osmotic Demyelination Syndrome After Liver Transplantation: A Multidisciplinary Perspective

BET Proteins: An Approach to Future Therapies in Transplantation

Mobile Health in Solid Organ Transplant: The Time Is Now

Complement Polymorphisms in Kidney Transplantation: Critical in Graft Rejection?

Applying Mass Cytometry to the Analysis of Lymphoid Populations in Transplantation

The Therapeutic Potential of T Cell Metabolism

Total Recall: Can We Reshape T Cell Memory by Lymphoablation?

Transplant Infectious Diseases: A Review of the Scientific Registry of Transplant Recipients Published Data

How Spain Reached 40 Deceased Organ Donors per Million Population

Urinary MicroRNA as Biomarker in Renal Transplantation

Implications of Resident Memory T Cells for Transplantation

Long-Term Medical and Psychosocial Outcomes in Living Liver Donors

Long-Term Non–End-Stage Renal Disease Risks After Living Kidney Donation

Treg-Centric View of Immunosuppressive Drugs in Transplantation: A Balancing Act

Peripheral Blood Epstein–Barr Viral Nucleic Acid Surveillance as a Marker for Posttransplant Cancer Risk

Systems Biology in Kidney Transplantation: The Application of Multi-Omics to a Complex Model

Alarmins and Their Receptors as Modulators and Indicators of Alloimmune Responses

The Role of Neutrophils in Transplanted Organs

Induction Therapy for Kidney Transplant Recipients: Do We Still Need Anti-IL2 Receptor Monoclonal Antibodies?

 

 

2016

Comprehensive Reviews

Transplantation and Damage-Associated Molecular Patterns (DAMPs)

DAMP—Induced Allograft and Tumor Rejection: The Circle Is Closing

Unlocking the Potential of Purinergic Signaling in Transplantation

The Cell Biology of Cytomegalovirus: Implications for Transplantation

Functional Immune Anatomy of the Liver—As an Allograft

A2/A2B to B Renal Transplantation: Past, Present, and Future Directions

Minireviews

Micro and Nano Material Carriers for Immunomodulation

Increasing the Use of Kidneys From Unconventional and High-Risk Deceased Donors

Targeting the Notch Pathway to Prevent Rejection

Clinical Implications of Basic Science Discoveries: Microchimerism Finds a Major Role in Reproductive Success; but Does It Also Contribute to Transplant Success?

On Patients Who Purchase Organ Transplants Abroad

Protecting the Kidney in Liver Transplant Candidates: Practice-Based Recommendations From the American Society of Transplantation Liver and Intestine Community of Practice

Protecting the Kidney in Liver Transplant Recipients: Practice-Based Recommendations From the American Society of Transplantation Liver and Intestine Community of Practice

Systematic Review and Meta-Analysis of the Impact of Computed Tomography–Assessed Skeletal Muscle Mass on Outcome in Patients Awaiting or Undergoing Liver Transplantation

Aryl Hydrocarbon Receptor–Dependent Pathways in Immune Regulation

Immune Exhaustion and Transplantation

Survival Analysis in the Presence of Competing Risks: The Example of Waitlisted Kidney Transplant Candidates

Liver-Regenerative Transplantation: Regrow and Reset

The “ABC” of Virus-Specific T Cell Immunity in Solid Organ Transplantation

The Revised (2013) Banff Classification for Antibody-Mediated Rejection of Renal Allografts: Update, Difficulties, and Future Considerations

Environmental Exposures—The Missing Link in Immune Responses After Transplantation

The Emerging Role of DNA Methylation in Kidney Transplantation: A Perspective

The Role of Lymphoid Neogenesis in Allografts

Obesity-Associated Adipose Tissue Inflammation and Transplantation

Natural Killer Cells and Liver Transplantation: Orchestrators of Rejection or Tolerance?

An Update on Heart Transplantation in Human Immunodeficiency Virus–Infected Patients

Humanized Mouse Models for Transplant Immunology

BK Polyomavirus Infection and Renourinary Tumorigenesis

 

 

2015

Comprehensive Reviews

Regulatory T Cells in Kidney Transplantation: New Directions?

Anatomical Variation and Its Management in Transplantation

Renal Allograft Fibrosis: Biology and Therapeutic Targets

A Complete Treatment of Adult Living Donor Liver Transplantation: A Review of Surgical Technique and Current Challenges to Expand Indication of Patients

Innate Lymphoid Cells in Graft-Versus-Host Disease

Minireviews

Cell-Free DNA: An Upcoming Biomarker in Transplantation

Pharmacokinetics and Toxicity of Tacrolimus Early After Heart and Lung Transplantation

Challenges and Clinical Decision-Making in HIV-to-HIV Transplantation: Insights From the HIV Literature

Blood Vessels in Allotransplantation

Tempering Allorecognition to Induce Transplant Tolerance With Chemically Modified Apoptotic Donor Cells

Emerging Issues With Diagnosis and Management of Fungal Infections in Solid Organ Transplant Recipients

HLA Epitopes as Viewed by Antibodies: What Is it All About?

A Mine Is a Terrible Thing to Waste: High Content, Single Cell Technologies for Comprehensive Immune Analysis

Proposed Management Algorithm for Severe Hypoxemia After Liver Transplantation in the Hepatopulmonary Syndrome

Evolving Perspectives of mTOR Complexes in Immunity and Transplantation

Rotavirus in Organ Transplantation: Drug-Virus-Host Interactions

The Putative Role of Mast Cells in Lung Transplantation

Minireviews—Clinical Implications of Basic Science Discoveries 

Clinical Implications of Basic Science Discoveries: Immune Homeostasis and the Microbiome—Dietary and Therapeutic Modulation and Implications for Transplantation

Clinical Implications of Basic Science Discoveries: Nociceptive Neurons as Targets to Control Immunity—Potential Relevance for Transplantation

Clinical Implications of Basic Science Discoveries: Induced Pluripotent Stem Cell Therapy in Transplantation—A Potential Role for Immunologic Tolerance

Clinical Implications of Basic Science Discoveries: Janus Resurrected—Two Faces of B Cell and Plasma Cell Biology

 

 

2014

 

Comprehensive Reviews

Hepatitis C Virus Infection and Kidney Transplantation in 2014: What's New?

HLA Antibody Detection With Solid Phase Assays: Great Expectations or Expectations Too Great?

Big Data in Organ Transplantation: Registries and Administrative Claims

The Microbiota, the Immune System and the Allograft

Harnessing Regulatory T Cells for Clinical Use in Transplantation: The End of the Beginning

Diagnosis and Management of Antibody-Mediated Rejection: Current Status and Novel Approaches

Minireviews

Braking Bad: Novel Mechanisms of CTLA-4 Inhibition of T Cell Responses

Building New Hearts: A Review of Trends in Cardiac Tissue Engineering

CD28 Negative T Cells: Is Their Loss Our Gain?

Toward a Better Liver Graft Allocation That Accounts for Candidates With and Without Hepatocellular Carcinoma

Evaluation of Solid Organ Transplant Candidates for Coronary Artery Disease

The Current State of Intestine Transplantation: Indications, Techniques, Outcomes and Challenges

Understanding the CD28/CTLA-4 (CD152) Pathway and Its Implications for Costimulatory Blockade

Autophagy: Basic Principles and Relevance to Transplant Immunity

The Role of Hypoxia-Inducible Factors in Organ Donation and Transplantation: The Current Perspective and Future Opportunities

Death-Defining Immune Responses After Apoptosis

New Cell-Signaling Pathways for Controlling Cytomegalovirus Replication

Vitamin D in Renal Transplantation – from Biological Mechanisms to Clinical Benefits

Directly Acting Antivirals (DAAs) for the Treatment of Chronic Hepatitis C Virus Infection in Liver Transplant Patients: “A Flood of Opportunity”

Transplantation Genetics: Current Status and Prospects

The Purinergic System in Allotransplantation

Emerging Functions of Autophagy in Kidney Transplantation

 

 

2013

Comprehensive Reviews

Biliary Complications After Liver Transplantation: Old Problems and New Challenges

Minireviews

Emerging Role of Gasotransmitters in Renal Transplantation

Necroptosis in Immunity and Ischemia-Reperfusion Injury

Biological Implications of Extracellular Adenosine in Hepatic Ischemia and Reperfusion Injury

Osteoimmunology and Its Implications for Transplantation

Mycophenolate Fetal Toxicity and Risk Evaluation and Mitigation Strategies

Qualitative Research in Organ Transplantation: Recent Contributions to Clinical Care and Policy

Plasmacytoid Dendritic Cells: No Longer an Enigma and Now Key to Transplant Tolerance?

A Thematic Analysis of Quality of Life in Lung Transplant: The Existing Evidence and Implications for Future Directions

LIGHT/HVEM/LTßR Interaction as a Target for the Modulation of the Allogeneic Immune Response in Transplantation

Bronchoalveolar Lavage as a Tool to Predict, Diagnose and Understand Bronchiolitis Obliterans Syndrome

Recent Progress in the Pathophysiology and Treatment of FSGS Recurrence

MicroRNAs as Biomarkers in Solid Organ Transplantation

Disruptions in the Supply of Medications Used in Transplantation: Implications and Management Strategies for the Transplant Clinician

 

 

2012

Comprehensive Reviews

The Future of Heart Transplantation

Role of the PD-1 Pathway in the Immune Response

T Cell Autoreactivity in the Transplant Milieu

Lymphodepletion and Homeostatic Proliferation: Implications for Transplantation

Advances in Direct T-Cell Alloreactivity: Function, Avidity, Biophysics and Structure

Minireviews

Liver Defatting: An Alternative Approach to Enable Steatotic Liver Transplantation

The Nephroprotective Properties of Recombinant Human Erythropoietin in Kidney Transplantation: Experimental Facts and Clinical Proofs

New Insights on Molecular Mechanisms of Renal Aging

The Role of Costimulatory Molecules in Directing the Functional Differentiation of Alloreactive T Helper Cells

Calcineurin Inhibitor Sparing With Mycophenolate Mofetil in Liver Transplantion: A Systematic Review of Randomized Controlled Trials

Informed Consent for Living Donation: A Review of Key Empirical Studies, Ethical Challenges and Future Research

Hepatitis E Virus: What Transplant Physicians Should Know

Dyslipidemia and Its Therapeutic Challenges in Renal Transplantation

Can the Government Ban Organ Sale? Recent Court Challenges and the Future of US Law on Selling Human Organs and Other Tissue

CD28-Specific Immunomodulating Antibodies: What Can Be Learned From Experimental Models?

Renal Comorbidity After Solid Organ and Stem Cell Transplantation

A Need for Biomarkers of Operational Tolerance in Liver and Kidney Transplantation

The Molecular Legacy of Apoptosis in Transplantation

With Respect to Elderly Patients: Finding Kidneys in the Context of New Allocation Concepts

Nonhuman Primate Transplant Models Finally Evolve: Detailed Immunogenetic Analysis Creates New Models and Strengthens the Old

New-Onset Diabetes After Kidney Transplantation—Changes and Challenges

Current Status of Organ Transplantation in Japan

Diabetes Mellitus Following Liver Transplantation in Patients With Hepatitis C Virus: Risks and Consequences

Is Prevention the Best Treatment? CMV After Lung Transplantation

Transplant Accommodation—Are the Lessons Learned from Xenotransplantation Pertinent for Clinical Allotransplantation?

Bioartificial Lung Engineering

Microvesicles as Novel Biomarkers and Therapeutic Targets in Transplantation Medicine

Hepatic Transplant and HCV: A New Playground for an Old Virus

Digital Transplantation Pathology: Combining Whole Slide Imaging, Multiplex Staining and Automated Image Analysis

Donor Age-Specific Injury and Immune Responses

 

 

2011

Comprehensive Reviews

Delayed Graft Function in the Kidney Transplant

Major Challenges Limiting Liver Transplantation in the United States

Minireviews

Matchmaking the B-Cell Signature of Tolerance to Regulatory B Cells

Bone Marrow-Derived Cell Transplantation Therapy for Myocardial Infarction: Lessons Learned and Future Questions

The Emerging Role of the TIM Molecules in Transplantation

Blood Transfusions in Organ Transplant Patients: Mechanisms of Sensitization and Implications for Prevention

Liver Ischemia and Reperfusion Injury: New Insights into Mechanisms of Innate—Adaptive Immune-Mediated Tissue Inflammation

Surveillance Protocol Kidney Transplant Biopsies: Their Evolving Role in Clinical Practice

Targeting B Cells and Antibody in Transplantation

The Emerging Role of Brazil in Clinical Trial Conduct for Transplantation

An Update on Donor-Derived Disease Transmission in Organ Transplantation

Epstein–Barr Virus-Related Post-Transplant Lymphoproliferative Disorders: Pathogenetic Insights for Targeted Therapy

Paradoxical Aspects of Rapamycin Immunobiology in Transplantation

Crosstalk between Complement and Toll-like Receptor Activation in Relation to Donor Brain Death and Renal Ischemia-Reperfusion Injury

Clinical Aspects of Intravenous Immunoglobulin Use in Solid Organ Transplant Recipients

 

 

2010

Retroviral Restriction Factors and Infectious Risk in Xenotransplantation

Thrombotic Microangiopathy After Kidney Transplantation

The International Normalized Ratio (INR) in the MELD Score: Problems and Solutions

Natural Killer Cells and the Immune Response in Solid Organ Transplantation

Valganciclovir: Recent Progress 

Recent Progress and New Perspectives in Studying T Cell Responses to Allografts

T Cell-mediated Rejection of Kidney Transplants: A Personal Viewpoint 

Antibody-Mediated Rejection: Emergence of Animal Models to Answer Clinical Questions 

Evolving Paradigms That Determine the Fate of an Allograft 

Phenotypic Expression of Recurrent Disease After Liver Transplantation 

Donor Intervention and Organ Preservation: Where Is the Science and What Are the Obstacles?

MicroRNAs as Immune Regulators: Implications for Transplantation

Recurrent Primary Biliary Cirrhosis After Liver Transplantation

Renal Transplantation Across HLA and ABO Antibody Barriers: Integrating Paired Donation into Desensitization Protocols

Donor Screening for Human T-cell Lymphotrophic Virus 1/2: Changing Paradigms for Changing Testing Capacity  

Tolerogenic Dendritic Cells: All Present and Correct? 

Metabolic Syndrome and Solid-Organ Transplantation