We are the unrivalled scientific journal for chirality research. Chirality publishes original contributions on the role of chirality in chemistry and biochemistry and its biological, chemical, materials, pharmacological, spectroscopic and physical properties.

Our scope encompasses fields such as chemistry (physiochemical, preparative synthetic, and analytical), physics, pharmacology, clinical pharmacology, toxicology, and other biological aspects of chiral molecules.

 

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  • 3Journal Impact Factor
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RESEARCH ARTICLE

Chiral Post-Modification of UiO-66-NH2 on Gas Chromatography Chiral Separation

  •  17 July 2025

Graphical Abstract

Chiral Post-Modification of UiO-66-NH2 on Gas Chromatography Chiral Separation Issue 8, 2025

A particular type of zirconium metal–organic framework (MOF) called chiral UiO-66 was created to serve as a stationary phase in gas chromatography. It successfully achieved high-resolution separation of enantiomers, such as linalool and α-pinene, as well as positional isomers. This MOFs is effective for chiral analysis in the chemical and pharmaceutical industries.

RESEARCH ARTICLE

Chiral Separation and Molecular Simulation of Five Quinolones on a Bonded Amylose[(S)-α-Methylbenzyl Carbamate] Column (CHIRALPAK IH) and the Elucidation of Its Recognition Mechanism

  •  17 July 2025

Graphical Abstract

Chiral Separation and Molecular Simulation of Five Quinolones on a Bonded Amylose[(S)-α-Methylbenzyl Carbamate] Column (CHIRALPAK IH) and the Elucidation of Its Recognition Mechanism Issue 8, 2025

This study revealed that hydrogen bonding, π–π stacking, and hydrophobic interactions are the key interacting forces driving the enantioseparation.

RESEARCH ARTICLE
Open access

Stokes Spectropolarimetry Applied to Measure Circular Birefringence Dispersion of Aqueous Solutions of Sugars

  •  8 July 2025

Graphical Abstract

Stokes Spectropolarimetry Applied to Measure Circular Birefringence Dispersion of Aqueous Solutions of Sugars Issue 7, 2025

This work demonstrates the use of Stokes spectropolarimetry (SSP) to investigate optical rotatory dispersion (ORD), or circular birefringence (CB), of chiral sugar solutions. The results confirm the relationship between concentration and optical rotation, the dependence on wavelength, and the versatility of SSP to characterize optical anisotropies.

RESEARCH ARTICLE

Electrochemiluminescent Chiral Sensor Based on Covalent Organic Frameworks for Discrimination of Phenylalanine Enantiomers

  •  6 July 2025

Graphical Abstract

Electrochemiluminescent Chiral Sensor Based on Covalent Organic Frameworks for Discrimination of Phenylalanine Enantiomers Issue 7, 2025

An electrochemiluminescent chiral sensor based on covalent organic frameworks (CC-MP CCTF) enables sensitive and selective discrimination of phenylalanine enantiomers.

RESEARCH ARTICLE

Automated Evaluation Method for Aggregation‐Induced Circularly Polarized Luminescence of Platinum(II) Complexes With 1,1′‐Bi‐2‐naphthol Derivatives as Ligands

  •  4 July 2025

Graphical Abstract

Automated Evaluation Method for Aggregation-Induced Circularly Polarized Luminescence of Platinum(II) Complexes With 1,1′-Bi-2-naphthol Derivatives as Ligands Issue 7, 2025

An automated high-throughput circularly polarized luminescence (HTCPL) system capable of simultaneously obtaining both circularly polarized luminescence (CPL) and luminescence spectra was used to evaluate the aggregation-induced CPL (AICPL) properties of newly synthesized platinum complexes. This study demonstrates that the HTCPL system effectively reduces human error and improves measurement efficiency in the AICPL evaluation process.

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Open access

Chiral phonons: circularly polarized Raman spectroscopy and ab initio calculations in a chiral crystal tellurium

  • Chirality
  •  338-345
  •  9 March 2023

Graphical Abstract

Chiral phonons: circularly polarized Raman spectroscopy and ab initio calculations in a chiral crystal tellurium Issue 6, 2023

We observed a chiral phonon in chiral unary crystal tellurium using circularly polarized Raman spectroscopy. By comparing the experiment and ab initio calculation, we determined the handedness of tellurium. We also evaluated the chirality of the phonons by a measure having the symmetry same as electric toroidal monopole.

Open access

Chiral stationary phases and applications in gas chromatography

  • Chirality
  •  732-759
  •  22 March 2022

Graphical Abstract

Chiral stationary phases and applications in gas chromatography Issue 5, 2022

This review article focuses on the development of chiral stationary phases for gas chromatography. The fundamental mechanisms of the recognition and separation of enantiomers and the selectors and chiral stationary phases used in chiral gas chromatography are presented. An overview over syntheses and applications of these chiral stationary phases is presented as a practical guidance for enantioselective separation of chiral compound classes and substances by gas chromatography.

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