Mass Spectrometry in Drug Metabolism and Disposition: Basic Principles and Applications
About this book
Reviews
"It is a state-of-the-art and mostly comprehensive overview of the field. It will be a valuable source of information for all those who want to start in the fields of drug metabolism and MS, e.g., PhD students, but also senior scientists, etc." (Analytical and Bioanalytical Chemistry, 31 July 2012)
"Overall, Mass Spectrometry in Drug Metabolism and Pharmacokinetics is a valuable and interesting resource for a broad readership, including scientists starting to work in DMPK as well as undergraduate and graduate students getting involved in drug discovery and characterizationby means of MS." (J Am Soc Mass Spectrom, 2011)
"Placing the imaging technology in the context of the principles and applications of drug design, the book can serve as a textbook for either field." (Book New, 1 August 2011)
Author Bios
MINGSHE ZHU, PhD, is a drug metabolism researcher at Bristol-Myers Squibb, where he leads a team that investigates biotransformation in new drug discovery and preclinical drug metabolism and pharmacokinetics in development. His teams have provided key metabolism and disposition information for regulatory approval of Abilify® and NDA submission of Dapagliflozin. Dr. Zhu's research interests include LC/MS technology, optimization of ADME properties, metabolic activation, and regulatory drug metabolism. He has been frequently invited to speak and teach short courses at conferences/workshops and has coauthored over sixty research articles and one book.