Chapter 9
Common Liquid Chromatography–Mass Spectrometry (LC–MS) Methodology for Metabolite Identification
Lin Xu,
Lewis J. Klunk,
Chandra Prakash,
Lin Xu
Department of Drug Metabolism and Pharmacokinetics, Biogen Idec, Cambridge, Massachusetts, USA
Search for more papers by this authorLewis J. Klunk
Department of Drug Metabolism and Pharmacokinetics, Biogen Idec, Cambridge, Massachusetts, USA
Search for more papers by this authorChandra Prakash
Department of Drug Metabolism and Pharmacokinetics, Biogen Idec, Cambridge, Massachusetts, USA
Search for more papers by this authorLin Xu,
Lewis J. Klunk,
Chandra Prakash,
Lin Xu
Department of Drug Metabolism and Pharmacokinetics, Biogen Idec, Cambridge, Massachusetts, USA
Search for more papers by this authorLewis J. Klunk
Department of Drug Metabolism and Pharmacokinetics, Biogen Idec, Cambridge, Massachusetts, USA
Search for more papers by this authorChandra Prakash
Department of Drug Metabolism and Pharmacokinetics, Biogen Idec, Cambridge, Massachusetts, USA
Search for more papers by this authorBook Editor(s):Mike S. Lee, Mingshe Zhu,
Mingshe Zhu
Department of Biotransformation, Bristol-Myers Squibb Research and Development, Princeton, New Jersey, USA
Search for more papers by this authorSeries Editor(s): Mike S. Lee,
Summary
This chapter contains sections titled:
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Introduction
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Strategies for Metabolite Identification
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In Silico Tools
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Conclusions and Future Trends
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Acknowledgment
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References
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