Chapter 14

Distribution Studies of Drugs and Metabolites in Tissue by Mass Spectrometric Imaging

Richard F. Reich

Richard F. Reich

Department of Chemistry and Medicine University of Florida, Gainesville, Florida, USA

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Daniel P. Magparangalan

Daniel P. Magparangalan

Department of Chemistry and Medicine University of Florida, Gainesville, Florida, USA

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Timothy J. Garrett

Timothy J. Garrett

Department of Chemistry and Medicine University of Florida, Gainesville, Florida, USA

Department of Medicine, University of Florida, Gainesville, Florida, USA

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Richard A. Yost

Richard A. Yost

Department of Chemistry and Medicine University of Florida, Gainesville, Florida, USA

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First published: 14 March 2011
Citations: 1

Summary

This chapter contains sections titled:

  • Introduction

  • Tissue Imaging Techniques

  • Mass Spectrometric Imaging Background

  • MSI Methodology

  • Applications of MSI for Detection of Drug Metabolites in Tissue

  • Conclusions

  • Acknowledgments

  • References

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