SEMS contributed to comparable outcomes including postoperative complications, mortality, and long-term outcomes, but significantly reduced SSI. These findings support the broader adoption of SEMS in clinical practice, particularly requiring minimized invasiveness and improving patient quality of life are prioritized.

We revealed that subtotal gastrectomy (STG) has its advantage over total gastrectomy on shorter operation time, less complication rates, and lower body weight loss by meta-analysis. Although there are some controversies, STG can be an ideal option for patients with gastric cancer of upper third stomach.

The six autoantibodies (Sui1, p62, RalA, p53, NY-ESO-1 and c-myc) positive group had poor prognosis compared to autoantibody negative group. A panel of autoantibodies against a tumor associated antigen in esophageal cancer patients had an additive effect with SCC-Ag to detect esophageal SCC even in early stage.

Delayed initiation of adjuvant chemotherapy (AC) is associated with significantly poorer postoperative survival in patients with gastric cancer, irrespective of whether preoperative chemotherapy was administered. These findings emphasize the importance of timely AC initiation to improve long-term outcomes in this patient population.

Male gender and pathological lymph node metastasis are independent poor prognostic factors in patients with esophageal cancer who receive upfront treatment followed by surgery and achieved pathological complete response of the primary tumor. Among patients without pathological lymph node metastasis, the upfront chemotherapy group showed significantly better both overall and relapse-free survival than the upfront chemoradiotherapy group.

In this nationwide inpatient database study of 5229 patients aged 70–79 years who underwent esophagectomy for cancer after neoadjuvant chemotherapy, overlap propensity score weighting analysis showed that neoadjuvant docetaxel-based triplet regimen (docetaxel, cisplatin, and 5-fluorouracil) was not associated with a higher incidence of perioperative adverse events (major and respiratory complications, mortality, and 30-day unplanned readmission) compared with the doublet regimen (cisplatin and 5-fluorouracil). Propensity score matching and instrumental variable analyses yielded similar results.

The cutoff value of CRP by sex for poor OS remains unclear. This study aimed to determine the cutoff values of CRP on postoperative day 3 to predict poor OS in men and women with gastric cancer after radical gastrectomy. The high-CRP group has poorer overall survival than the low-CRP group for gastric cancer after gastrectomy. High-CRP was an independent poor prognostic factor for overall survival, regardless of postoperative complications.

This retrospective study investigated risk factors for surgical site infections (SSIs) in right-sided colon cancer surgeries using intracorporeal anastomosis (IA). The results demonstrated that preoperative oral antibiotics (OA) significantly reduced SSI rates, with OA identified as an independent protective factor, suggesting its beneficial role in decreasing postoperative infection risks.

Anastomotic stenosis and late fistula formation frequently emerge as secondary consequences of early AL, and represent significant complications linked to permanent stoma creation, often proving resistant to treatment. Intestinal prolapse is a characteristic anastomotic complication of ISR that can be caused by excessive intestinal mobilization. These findings provide valuable insights into guiding sphincter-sparing surgery for lower rectal cancer and highlight aspects that have not been fully understood until now.

This economic evaluation used a Markov state-transition model to analyze the cost-effectiveness of surveillance strategies recommended by various academic societies. This study found that the surveillance program proposed by the Japanese Society for Cancer of the Colon and Rectum (JSCCR) was the most cost-effective, with an incremental cost-effectiveness ratio of 19 256 USD compared with the next most cost-effective program. These findings suggest that intensive postoperative surveillance as recommended by the JSCCR is acceptable for stage IV colorectal cancer.

We retrospectively compared intracorporeal and extracorporeal anastomosis in patients undergoing laparoscopic colectomy for colon cancer in 46 institutions by using propensity-score matching. Intracorporeal anastomosis showed advantages over extracorporeal anastomosis in terms of blood loss, intraoperative vascular injury, bowel recovery, and length of hospital stay, despite a longer operative time.

Preoperative GPS2 is an independent poor prognostic factor in patients with colorectal cancer and synchronous peritoneal metastases, and surgical resection does not improve prognosis in patients with GPS2. Preoperative GPSs may be used as indicators for surgical resection of synchronous peritoneal metastases.

Blue LED irradiation targeted metabolic coupling between CAFs and colon cancer cells.

This study aimed to clarify whether differences in minimally invasive surgery outcomes are associated with regional and patient characteristics. This study found regional and patient characteristic disparities in minimally invasive surgical outcomes; national policies should be implemented to address these inequities.

Adjuvant completion with early initiation may contribute to the improved survival of patients with pancreatic ductal adenocarcinoma.

Prolonged administration of antimicrobial prophylaxis might not be effective to prevent surgical site infections after distal pancreatectomy compared to intraoperative or up to 24-h administration.

Osteopenic occult vertebral fracture (OVF) was associated with poor long-term outcomes in patients with HCC after hepatic resection. Osteopenic OVF had a poorer prognosis than that of patients with either osteopenia or OVF.

This retrospective study evaluates the prognostic factors in patients undergoing curative hepatic resection for rectal cancer liver metastases. It identifies lateral lymph node metastasis and perineural invasion as significant prognostic factors. Moreover, patients with these factors required nonsurgical treatment in the early postoperative period.

The postoperative nutritional status of patients with familial adenomatous polyposis who underwent pancreas-sparing total duodenectomy was better than that of patients who underwent pancreaticoduodenectomy. This study provides the first direct comparison of postoperative nutritional outcomes between patients with pancreas-sparing total duodenectomy and those with pancreaticoduodenectomy.

The effectiveness of intraperitoneal chemotherapy using paclitaxel (i.p.-PTX) in pancreatic ductal adenocarcinoma (PDAC) patients with peritoneal dissemination remains elusive. This study indicated that the i.p.-PTX therapy may improve survival in selected patients with PDAC, in particular those with occult peritoneal dissemination.

PDAC patients with the radiological severe interface (≥25 contact length and ≥210 degrees circumferential tumor-SMV/PV interface) may help predict poor survival outcomes preoperatively.

This study verified the effective implementation of robotic distal pancreatectomy as the standard approach in our strategic robotic surgical oncology program. Although an institutional learning curve was observed, the robotic surgery program successfully expanded the number of primary operating surgeons while maintaining stable short-term outcomes.

We developed a novel super subtotal gastrectomy (SSTG) technique for upper-third gastric cancer near the esophagogastric junction. This method preserves the gastric fornix, a major site of ghrelin secretion, while maintaining an oral margin beyond the esophageal junction. SSTG offers a potential solution for reducing postoperative complications such as weight loss and appetite reduction.