Highlights

• In Chinese postmenopausal women with type 2 diabetes mellitus, serum follicle-stimulating hormone levels were negatively and independently associated with the prevalence of nonalcoholic fatty liver disease.
• Metabolic conditions, including overweight/obesity, central obesity, hyperuricemia, hypertension, and dyslipidemia did not interact with this association.
• Follicle-stimulating hormone might be a potential independent index for screening and identifying individuals with high risk of non-alcoholic fatty liver disease in postmenopausal women with type 2 diabetes mellitus.

Highlights

• MicroRNAs (miRNAs) are overexpressed in inflammation, insulin resistance, and type 2 diabetes mellitus (T2DM).
• Many types of miRNAs are changed during the T2DM progression.
• miRNAs have a potential role as a biomarker in T2DM diagnosis.

Highlights

• Interventional techniques offer novel therapeutic approaches for metabolic disorders such as obesity and type 2 diabetes mellitus, with advantages such as less invasiveness, fewer potential complications, and lower costs.
• By embolizing specific arteries feeding ghrelin-producing cells, bariatric arterial embolization not only promotes weight loss but also has potential effects on glucometabolism.
• Endovascular denervation targets nerves that regulate metabolic organs to improve glycemic control. The detailed mechanism and long-term effects are under research.
• A new territory named “Interventional Metabology” was proposed to encompass various interventional approaches to treating metabolic disorders.

Highlights

• In people with type 2 diabetes, the risk of all-cause, cardiovascular disease, and cancer mortality increased with higher gamma-glutamyl transferase (GGT) concentrations.
• Stronger effects of GGT levels and all-cause mortality were observed in the group with body mass index <25 kg/m² and those with dyslipidemia.
• GGT could potentially be used to predict the risk of cardiovascular disease and cancer among people with type 2 diabetes.

Highlights

• Vascular complication is one of the most important causes of death in diabetes patients.
• Arterial stiffness plays a key role in the progress of diabetes vascular complication; therefore, the improvement of arterial stiffness could inhibit the process of atherosclerosis and reduce the burden of diabetes vascular complications
• This study first analyzed the potential antiarterial stiffness effect of six first-line antidiabetic drugs, providing new strategies for personalized glucose-lowering therapy.

Highlights

• This study is the first to evaluate the efficacy of the closed-loop system MiniMed 780G in children aged 6 to 17 years with type 1 diabetes previously receiving continuous subcutaneous insulin infusion and intermittent continuous glucose monitoring.
• This shows early results, with improvement in time in range and all hyperglycemia times, from the first 48 hours after system switch and for 6 months of follow-up.
• There was an improvement in the Pittsburgh Sleep Quality Index score at 3 months, although it was not significant compared to the baseline value, with a high percentage of satisfaction with the new system.