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    2025
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Review Article
Open Access

Dual Roles of Prostaglandin E2 (PGE2) in Bone Remodeling and Pain Management: Bridging the Gap in Osteoarthritis Research

Yulian Zhang,  Wenzhi Wu,  Zhuo Chen, 
  • First Published: 26 July 2025
Review Article
Open Access

Drugs Used in the Treatment of Viral Infections for the Prevention of Airway Remodeling in Asthma

Joanna Wieczfinska,  Rafal Pawliczak, 
  • First Published: 24 July 2025
Research Article
Open Access

MicroRNA-429 Inhibits Microglial Inflammation by Targeting IKKβ Through the NF-κB Pathway

Zhongling Ke,  Yanhui Chen,  Xiaoxia Lin,  Jilong Jiang, 
  • First Published: 24 July 2025
Research Article
Open Access

Based on Proteomics Data Revealing the Potential of Traditional Chinese Medicine in Treating Irritable Bowel Syndrome

Yizhan Wu,  Fei Guo,  Xiaoxia Xu,  Ya Liu,  Jiangwei Liu, 
  • First Published: 23 July 2025
Review Article
Open Access

Pharmacological Effects and Pharmacokinetic Profiles of Dehydroandrographolide

Chenggang Xu,  Yu Shen,  Lina Zhang,  Feng Wang,  Shuting Xiang, 
  • First Published: 23 July 2025
Retraction
Open Access

RETRACTION: lncRNA SNHG14 Plays a Role in Sepsis-Induced Acute Kidney Injury by Regulating miR-93

Mediators of Inflammation, 
  • First Published: 21 July 2025

Research Article
Open Access

G Protein-Coupled Receptor 30 Attenuates Neuronal Pyroptosis Induced by Subarachnoid Hemorrhage

Jun Peng,  Xiqi Hu,  Jun He,  Ying Xia, 
  • First Published: 21 July 2025
Research Article
Open Access

Integrating GEO Database, Mendelian Randomization, and Molecular Docking to Identify HLA-C as a Potential Therapeutic Target for Periodontitis

ChengJi Shi,  Xinyi Ou,  LiJuan Huang,  XiaoXu Lei,  ShuHao Xu,  Menglu Ou,  Wei Li,  Xi Zhao, 
  • First Published: 15 July 2025
Research Article
Open Access

The Negative Feedback of the Glutamine/Prostatitis Loop Identified Among 1400 Metabolites and Prostatitis via Mendelian Randomization

Yi Wang,  Hao Ji,  Yingfei Chen,  Bingye Zhu,  Yongming Peng,  Qianwei Xing, 
  • First Published: 15 July 2025
Research Article
Open Access

Association of Albumin–Bilirubin (ALBI) Grade With 28-Day All-Cause Mortality in Patients With Acute Respiratory Distress Syndrome: A Retrospective Analysis of the MIMIC-IV Database

Weixiao Chen,  Qingzhou Chen,  Zhiwei Tang,  Zhibo Li,  Weiyan Chen,  Xuming Xiong,  Deliang Wen,  Zhenhui Zhang, 
  • First Published: 14 July 2025
Research Article
Open Access

The Effects of Probiotic–Prebiotic Use on Acute Inflammatory Parameters in Patients Receiving Pelvic Radiotherapy: A Prospective Multicenter Study

Muge Akmansu,  Sefika Dincer,  Esra Kaytan Saglam,  Zuleyha Akgun,  Hatice Pasaoglu, 
  • First Published: 13 July 2025
Research Article
Open Access

Lymphocyte-to-Monocyte Ratio and All-Cause Mortality in Populations With Abdominal Aortic Calcification: A Prospective Cohort Study

Jingjing Huang,  Chunyong Chen, 
  • First Published: 12 July 2025
Research Article
Open Access

Phytochemical Screening and In Vitro Antioxidant and Anticancer Evaluation of Stem and Leaf Extracts of Cissampelos pareira L.

Arthid Thim-uam,  Chutamas Thepmalee,  Wittaya Chaiwangyen,  Napapan Kangwan,  Ratchanaporn Chokchaisiri,  Piyawan Nuntaboon,  Angkana Songkrao,  Amnart Onsa-ard, 
  • First Published: 11 July 2025
Research Article
Open Access

HMGB1 Exacerbates Intestinal Barrier Damage by Inducing Ferroptosis Through the TLR4/NF-κB/GPX4 Pathway in Ulcerative Colitis

Nannan Zhu,  Xiaoyuan Ge,  Lixue Zhang,  Xinwen Chen,  Weizhen Xiang,  Qiao Mei, 
  • First Published: 11 July 2025
Research Article
Open Access

Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage Polarization

Jiahui Lin,  Lingling Ke,  Sha Cheng,  Wei Lu,  Yanan Hu,  Xiyi He,  Tingting Luo,  Yuting Liu,  Canxia Xu,  Jian Qi, 
  • First Published: 11 July 2025
Research Article
Open Access

Clinical Significance of Low-Density Granulocytes in Acute Pancreatitis

Jiren Wang,  Xinwen Chen,  Youli Ke,  Nannan Zhu,  Jiejie Zhu,  Hao Ding,  Linlin Pan,  Chenao Zhang,  Xingyu Liu,  Yumei Wu,  Huizhong Gan,  Qiao Mei, 
  • First Published: 11 July 2025
Research Article
Open Access

Development of a Starvation Response–Based Model and Its Application in Prognostic Assessment of Liver Hepatocellular Carcinoma

Xinjun Hu,  Yafeng Liu,  Shujun Zhang,  Kaijie Liu,  Xinyu Gu, 
  • First Published: 07 July 2025
Research Article
Open Access

Evaluation of Gene Expression and the Regulatory Role of microRNAs Related to the Mitogen-Activated Protein Kinase Signaling Pathway in Human Retinal Pigment Epithelial Cells Treated With Lipopolysaccharide A and Tacrolimus

Aleksandra Kiełbasińska,  Katarzyna Krysik,  Dominika Janiszewska-Bil,  Martyna Machaj,  Zuzanna Lelek,  Mariola Szulik,  Patrycja Mickiewicz,  Anita Lyssek-Boroń,  Beniamin Oskar Grabarek, 
  • First Published: 01 July 2025
Research Article
Open Access

Association Between Dietary Inflammatory Index and NAFLD: A Cross-Sectional Study of the National Health and Nutrition Examination Survey

Yuan He,  Yuhang Yang,  Pengfei Cheng,  Wei Zhang,  Jinghan Jia,  Dawei Ye,  Jinxi Wang, 
  • First Published: 01 July 2025
Research Article
Open Access

Association Between Domain-Specific Physical Activity and Novel Inflammatory Biomarkers Among US Adults: Insights From NHANES 2007–2018

Xin-ying Liu,  Kai Yao, 
  • First Published: 24 June 2025
Research Article
Open Access

Prognostic Significance of the Serum Creatinine Level During the Shock Stage in Severe Burn Patients: A 10-Year Retrospective Study

Wei Zhu,  Xiaorong Xie,  Ziqin Shu,  Li Li,  Gaozhong Hu,  Huapei Song, 
  • First Published: 23 June 2025
Research Article
Open Access

Analysis of the Correlation Between MDS Inflammatory Indicators and Clinical Characteristics: A Comprehensive Analysis

ZhongLi Hu,  Lijia Pei,  ZhongTing Hu,  YanLi Yang,  YuXian Wang,  Mengqing Hua,  Ping Zhao, 
  • First Published: 19 June 2025
Research Article
Open Access

WTAP Accelerates Exhaustion of CD8+ T Cells and Progression of Hepatocellular Carcinoma by Promoting m6A Modification and Translation of PD1 mRNA

Rong Li,  Shunle Li,  Hua Li,  Bingli Liu,  Zimu Wang,  Huanqin Lei,  Yuting Li,  Lijuan Jia,  Junhui Li,  Hongwei Lu,  Meng Xu, 
  • First Published: 18 June 2025
Review Article
Open Access

Unraveling the Gut–Liver–Brain Axis: Microbiome, Inflammation, and Emerging Therapeutic Approaches

Hiral Aghara,  Manali Patel,  Prashsti Chadha,  Kirti Parwani,  Ruchi Chaturvedi,  Palash Mandal, 
  • First Published: 18 June 2025
Research Article
Open Access

Inflammatory Markers Mediate the Association Between Cardiovascular Health and Chronic Inflammatory Airway Diseases: A Cross-Sectional Study on the Population Aged 50 Years and Above From NHANES 2013–2018

Zhaoqi Yan,  Xiufan Du,  Jing Zhang, 
  • First Published: 16 June 2025
Research Article
Open Access

Bone Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect Articular Cartilage Through Regulating tRF-Gln-TTG-019/UBL3

Xialin Li,  Zheng Huang,  Min Shu,  Guangxun Hu,  Weihong Yi,  Yang Duan,  Songjia Ni, 
  • First Published: 13 June 2025
Research Article
Open Access

Immune Regulation and ECM-Related Pathway Enrichment Reveal ATP2A3 as a Prognostic Biomarker for Nonspecific Orbital Inflammation: An Integrated Machine Learning and Mendelian Randomization Analysis

Zixuan Wu,  Xi Long,  Kang Tan,  Xiaolei Yao,  Qinghua Peng, 
  • First Published: 13 June 2025
Research Article
Open Access

S100A11 Promotes Acute Pancreatitis by Upregulating Acinar Cell Ferroptosis

Huiyun Zhu,  Hongxin Sun,  Xianzhu Zhou,  Ge Li,  Yun Zhang,  Youhan Zhang,  Jia Gui,  Siying Fei,  Xiaoyang Dong,  Xiaoju Su,  Yan Chen,  Cui Chen,  Yiqi Du, 
  • First Published: 13 June 2025
Research Article
Open Access

CCL2 Inhibitor Bindarit Improve Postoperative Cognitive Function by Attenuating Pericyte Loss-Related Blood–Brain Barrier Disruption and Neuroinflammation

Hui Yuan,  Bo Lu,  Daofan Sun,  Junping Chen,  Xiangming Fang, 
  • First Published: 12 June 2025
Research Article
Open Access

Investigation of the Renal Defensive Influence of Walnut Septa Extract Against Acute Renal Ischemia/Reperfusion Injury

Seda Askin,  Khasiiat Iminova,  Bahri Avci,  Hakan Askin, 
  • First Published: 12 June 2025
Research Article
Open Access

Temporal Effects of Disease Signature Genes and Core Mechanisms in the Hyperacute Phase of Acute Ischemic Stroke: A Bioinformatics Analysis and Experimental Validation

Peng-Li Ding,  Kai-Xin Zhang,  Fang Yao,  Wen-Qiang Cui,  Zhen-Ling Liu,  Yi-Ran Wang,  Xiang-Ying Wang,  Wei Liu,  Heng-Ye Zhao,  Hong-Yun Wu,  Ya-Han Wang,  Xiang-Qing Xu, 
  • First Published: 06 June 2025
Research Article
Open Access

Gut Microbiota-Derived Butyric Acid Alleviates Glucocorticoid-Associated Osteonecrosis of the Femoral Head via Modulating Inflammatory Cytokines in Bone Marrow Mesenchymal Stem Cells

Shuai He,  Hao Chen,  Hongzhong Xi,  Guangquan Sun,  Bin Du,  Xin Liu, 
  • First Published: 05 June 2025
Research Article
Open Access

Integrative Analysis of Shared Pathogenic Genes and Potential Mechanisms in Gardnerella vaginalis and Persistent HPV16 Infection

Ye Li,  Yue Wang,  Xianhua Liu,  Huifeng Xue,  Liying Wang,  Maotong Zhang,  Pengming Sun, 
  • First Published: 05 June 2025
Research Article
Open Access

The Tumor-Associated Neutrophils-Related Signatures Predict Prognosis and Indicate Immune Landscape in Colorectal Carcinoma

Ying Wang,  Yizhen Zhu,  Yuling Zeng,  Shuhui Gao,  Youcai Tang,  Ming Wei, 
  • First Published: 05 June 2025
Research Article
Open Access

Gut Microbiota in Lactose Intolerance: A Mendelian Randomization Study on Microbial Mechanisms and Potential Links to Tumor Inflammatory Microenvironments

Ya Xie,  Qiongjiao Cao,  Zhen Huang,  Xin Zou, 
  • First Published: 05 June 2025
Retraction
Open Access

RETRACTION: Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis

Mediators of Inflammation, 
  • First Published: 29 May 2025

Review Article
Open Access

Trends and Hot Spots of Macrophages Linked to Metabolic Syndrome: A Comprehensive Bibliometric and Visualization Analysis (2014–2024)

Yuan Zhang,  Qiwang He,  Xiaoqian Cong,  Huazhou Qiu,  Chuan Hua, 
  • First Published: 24 May 2025
Research Article
Open Access

IL-13 May Could Enhance the Proliferation and Affect the Differentiation of Nasal Epithelium Basal Cells Through the mTOR/p70S6K1 Pathway in Chronic Rhinosinusitis With Nasal Polyps

Ping Li,  Tao Li,  Jinfeng Luo,  Peng Yu,  Tao Jiang,  Xiangmin Zhou,  Liang Yu,  Aiping Chen,  Yuzhu Wan,  Li Shi, 
  • First Published: 21 May 2025
Research Article
Open Access

Baicalin Modulates Glycolysis via the PKC/Raf/MEK/ERK and PI3K/AKT Signaling Pathways to Attenuate IFN-I-Induced Neutrophil NETosis

Hong Wei,  Dongni Xia,  Li Li,  Linpan Liang,  Lijun Ning,  Cuiliu Gan,  Ying Wu, 
  • First Published: 19 May 2025
Review Article
Open Access

IL-6 and Olfactory Dysfunction: Focus on Changes, Effects, and Mechanisms

Xiao-Yu Song,  Ya-Kui Mou,  Han-Rui Wang,  Yao Wang,  Wan-Chen Liu,  Ting Yang,  Cai-Yu Sun,  Chao Ren,  Xi-Cheng Song, 
  • First Published: 19 May 2025
Research Article
Open Access

The Mechanosensitive PIEZO1 Channel Contributes to the Reaction of RAW264.7 Macrophages to Mechanical Strain

Agnes Schröder,  Hanna Engelhardt,  Andressa Nogueira,  Björn Clausen,  Christian Kirschneck,  Jonathan Jantsch,  Peter Proff,  Kathrin Renner,  Eva Paddenberg-Schubert, 
  • First Published: 18 May 2025
Research Article
Open Access

Detection of the Prognostic Gene CYB5D2 in Cervical Squamous Epithelial Lesions

Yanan Liu,  Guoqiang Zhao,  Yanqing Kong,  Fengyuan Zhou,  Tong Zhang,  Xiaohang Chen,  Haiyan Hu,  Fengxiang Wei, 
  • First Published: 13 May 2025
Review Article
Open Access

Efficacy and Safety of Syk and BTK Inhibitors in Immune Thrombocytopenia: A Comprehensive Review of Emerging Evidence

Amirhossein Heidari,  Amirhossein Shahbazi Mazid,  Mohammad Behroozfar,  Negar Ghotbi,  Fatemeh Fathabadi,  Sara Eghbali,  Nazila Heidari, 
  • First Published: 10 May 2025
Research Article
Open Access

Association of Three Composite Inflammatory and Lipid Metabolism Indicators With Cardiovascular-Kidney-Metabolic Syndrome: A Cross-Sectional Study Based on NHANES 1999–2020

Jiayuan Song,  Ziyi Xu,  Han Yu,  Aimin Li,  Yiying Liu,  Meiying Jin, 
  • First Published: 08 May 2025
Review Article
Open Access

Cross Talk Between Macrophages and Podocytes in Diabetic Nephropathy: Potential Mechanisms and Novel Therapeutics

Siming Yu,  Zehui Han,  Chunsheng Li,  Xinxin Lu,  Yue Li,  Xingxing Yuan,  Dandan Guo, 
  • First Published: 02 May 2025
Review Article
Open Access

Pogostemon cablin Acts as a Key Regulator of NF-κB Signaling and Has a Potent Therapeutic Effect on Intestinal Mucosal Inflammation

Yuqing Deng,  Xin Liang,  Long Zhao,  Xin Zhou,  Jianqin Liu,  Zhi Li,  Shanshan Chen,  Guohui Xiao, 
  • First Published: 28 April 2025
Research Article
Open Access

Liangxue Qushi Zhiyang Decoction Inhibits Atopic Dermatitis in Mice via FcγR-Mediated Phagocytosis

Lili Zhang,  Linxian Li,  Zhanxue Sun, 
  • First Published: 27 April 2025
Research Article
Open Access

Mechanistic Insights Into GDFMD-Mediated Inhibition of Liver Fibrosis via miRNA-29b-3p Upregulation in Wilson’s Disease

Peng Huang,  Yuzhe Huang,  Ting Dong,  Han Wang,  Meixia Wang,  Xiang Li,  Wei Dong,  Yulong Yang,  Wei He,  Wenming Yang, 
  • First Published: 26 April 2025
Research Article
Open Access

Exploring the Relationship Between 91 Inflammatory Cytokines and IgA Nephropathy Using a Two-Sample Mendelian Randomization Study and the Gene Expression Omnibus Database

Manyi Wu,  Xingxin Yang,  Mengxiao Zou,  Xiaojing Cai,  Chunyu Pan,  Junhua Li,  Shuwang Ge, 
  • First Published: 26 April 2025
Research Article
Open Access

Influence of Altered Immune-Inflammatory Axis on the Risk of Osteomyelitis and Its Network Interaction Effect in European Population

Yangguang Lu,  Siyao Chen,  Ruotong Yao,  Feng Chen,  Yukai Wang,  Zihui Yuan,  Di Lu,  Haiyong Ren,  Xiang Wang,  Bingyuan Lin,  Qiaofeng Guo,  Kai Huang, 
  • First Published: 24 April 2025
Research Article
Open Access

Circulating Neutrophil-to-Lymphocyte Ratio Predicts Stroke-Associated Infection and Poststroke Fatigue Affecting Long-Term Neurological Outcomes in Stroke Patients

Lei Zuo,  Leiyu Geng,  Yujia Cao,  Xin-yu Zhou,  Wu Di,  Yun Liu,  Zhe Zhong,  Dandan Liu,  Zhengsheng Zhang,  Fuling Yan, 
  • First Published: 22 April 2025
Review Article
Open Access

Cardiac and Digestive Forms of Chagas Disease: An Update on Pathogenesis, Genetics, and Therapeutic Targets

Amanda Farage Frade,  Hélléa Guérin,  Joao Paulo Silva Nunes,  Luiz Felipe Souza e Silva,  Vinicius Moraes de Paiva Roda,  Rafael Pedro Madeira,  Pauline Brochet,  Pauline Andrieux,  Jorge Kalil,  Christophe Chevillard,  Edecio Cunha-Neto, 
  • First Published: 21 April 2025
Research Article
Open Access

Inhibition of the Notch Pathway Alleviates Nab-Paclitaxel-Induced Peripheral Neuropathic Pain in Rats by Suppressing HMGB1/Caveolin-1 Signaling in the Spinal Cord

Xing Wei,  Yaqing Zhou,  Li Ma,  Weimiao Li,  Changyou Shan,  Shuqun Zhang,  Yonglin Zhao, 
  • First Published: 18 April 2025
Research Article
Open Access

Dynamic and Static Effects of the Systemic Inflammatory Response Index on All-Cause Mortality in Individuals With Atherosclerotic Cardiovascular Disease: Evidence From National Health and Nutrition Examination Survey

Chenglin Duan,  Yihang Du,  Jiafan Chen,  Shuqing Shi,  Xiaohan Zhang,  Yuanhui Hu, 
  • First Published: 16 April 2025
Research Article
Open Access

The Association Between Sleep Disorder and Female Infertility: A Mediation Analysis of Inflammatory and Oxidative Markers

Qiaorui Yang,  Jinfu Zhang,  Zhenliang Fan, 
  • First Published: 16 April 2025
Research Article
Open Access

Exploring the Relationship Between Immune Cells and Chronic Kidney Disease by Mendelian Randomization, Colocalization Analysis, and SMR

Huiling Zhu,  Chaofan Qin,  Si Cheng,  Xi Zhang, 
  • First Published: 16 April 2025
Research Article
Open Access

Correlation of the Expression Profile of Peripheral Leukocyte and Liver Tissue Immune Markers With Serum Liver Injury Indices in Children With Biliary Atresia

Anna Helmin-Basa,  Izabela Kubiszewska,  Joanna B. Trojanek,  Małgorzata Wiese-Szadkowska,  Maria Janowska,  Zbigniew Kułaga,  Joanna Pawłowska,  Jacek Michałkiewicz, 
  • First Published: 16 April 2025
Research Article
Open Access

A Predictive Model for Acute Kidney Injury Based on Leukocyte-Related Indicators in Hepatocellular Carcinoma Patients Admitted to the Intensive Care Unit

Xiulan Peng,  Yahong Cai,  Huan Huang,  Haifeng Fu,  Wei Wu,  Lifeng Hong, 
  • First Published: 16 April 2025
Research Article
Open Access

Immune Landscape Variation in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Circulation Before and After Plasmapheresis by Single-Cell Transcriptome

Youzhou Tang,  Qingtai Cao,  Jishi Liu,  Quan Zhuang, 
  • First Published: 10 April 2025
Research Article
Open Access

Identification of Crohn’s Disease-Related Biomarkers and Pan-Cancer Analysis Based on Machine Learning

Tangyu Yuan,  Jiayin Xing,  Pengtao Liu, 
  • First Published: 04 April 2025
Research Article
Open Access

Causal Associations of Inflammatory Cytokines With Osteosarcopenia: Insights From Mendelian Randomization and Single Cell Analysis

Zugui Wu,  Jiyong Yang,  Yue Zhu,  Jiao Li,  Kang Xu,  Yuanlong Li,  Guoqing Zhong,  Yanfei Xu,  Ying Guo,  Yu Zhang, 
  • First Published: 03 April 2025
Research Article
Open Access

Electroacupuncture Improves Ovarian Function in Rats With Tripterygium Glycoside-Induced Diminished Ovarian Reserve by Promoting the Polarization of M2 Macrophages and Inhibiting Inflammatory Responses

Jia Luo,  Yantong Qin,  Yaoyao Zhu,  Yaoli Yin,  Meihong Shen, 
  • First Published: 31 March 2025
Research Article
Open Access

Mdivi-1 Attenuates Sepsis-Associated Acute Lung Injury by Inhibiting M1 Alveolar Macrophage Polarization and Pyroptosis

Xiaoyu Zhang,  Hui Fan,  Li Su,  Yanni Wang,  Guozhong Chen, 
  • First Published: 30 March 2025
Research Article
Open Access

Heterogeneity of Neutrophils and Immunological Function in Neonatal Sepsis: Analysis of Molecular Subtypes Based on Hypoxia–Glycolysis–Lactylation

Huabin Wang,  Ru Yang,  Nan Chen,  Xiang Li, 
  • First Published: 27 March 2025
Research Article
Open Access

Exploring the Relationship Between Immune Cells and Scoliosis by Mendelian Randomization, Colocalization Analysis, and SMR

Chaofan Qin,  Zhengjian Yan,  Qingshuai Yu,  Mingxin Chen,  Tao Hu,  Xin Wang,  Bo Lei,  Yu Chen,  Ke Ma,  Zhongliang Deng,  Si Cheng, 
  • First Published: 26 March 2025
Research Article
Open Access

Strain-Dependent Differences in Inflammatory/Immune Activity in Cutaneous Wound Tissue Repair in Rats: The Significance of Body Mass/Proneness to Obesity

Jelena B. Kulas,  Aleksandra D. Popov Aleksandrov,  Dusanka D. Popovic,  Anastasija Lj. Malesevic,  Maja M. Cakic Milosevic,  Milena V. Kataranovski,  Ivana I. Mirkov,  Dina M. Tucovic, 
  • First Published: 26 March 2025
Research Article
Open Access

Comparative Analysis of Salivary and Serum Inflammatory Mediator Profiles in Patients With Rheumatoid Arthritis and Periodontitis

Carina Fei,  Kaja Eriksson,  Guozhong Fei,  Luis Fernando Delgado Zambrano,  Shigufta Syed,  Caroline Lindström,  Martina Ericson,  Mehrad Mohammadi,  Georgios Tsilingaridis,  Amel Guenifi,  Rikard Holmdahl,  Leif Jansson,  Tülay Yucel-Lindberg, 
  • First Published: 20 March 2025
Research Article
Open Access

The Histone Deacetylase Activator ITSA-1 Improves the Prognosis of Cardiac Arrest Rats by Alleviating Systemic Inflammatory Responses Following Cardiopulmonary Resuscitation

Chenyu Zhang,  Hongyan Wei,  Qiang Zhang,  Haohong Zhan,  Yuanzheng Lu,  Yujie Li,  Bo Li,  Wen Huang,  Feng Nian,  Rong Liu,  Chunlin Hu,  Jie Chen, 
  • First Published: 20 March 2025
Review Article
Open Access

The Chronobiological and Neuroprotective Mechanisms of Resveratrol in Improving Sleep

Wenwen Zhu,  Ailin Gong,  Bin Zhang,  Hanxing Cheng,  Lishan Huang,  Xiao Wu,  Dechou Zhang,  Wenbin Dai,  Sen Li,  Houping Xu, 
  • First Published: 19 March 2025
Research Article
Open Access

Therapeutic Potential of Arginine-Loaded Red Blood Cell Nanovesicles Targeting Obese Asthma

Quoc Quang Luu,  Taejune Kim,  Thi Bich Tra Cao,  Injung Choi,  Seung Yun Yang,  Beum-Soo An,  Dae Youn Hwang,  Youngwoo Choi,  Hae-Sim Park, 
  • First Published: 19 March 2025
Research Article
Open Access

Neutrophil-to-Lymphocyte Ratio as a Potential Predictive Marker for Epileptic Seizures: Unveiling the “V”-Shaped Link

Xianmei Wang,  Yang Zhang,  Yi Ye,  Long Wang,  Yi Xu,  Siying Ren,  Likun Wang,  Guofeng Wu, 
  • First Published: 19 March 2025
Research Article
Open Access

The Association Study Between Cytokines and the Risk for Cerebral Palsy

Baotian Wang,  Fan Wang,  Li Yang,  Junhong Jiang,  Jiulai Tang,  De Wu, 
  • First Published: 17 March 2025
Research Article
Open Access

Faecalibacterium prausnitzii Colonization Attenuates Gut Inflammation and Epithelial Damage in a DSS-Induced Colitis Mice Model

Meng-Chuan Liu,  Yu-An Shu,  Yu-Chin Wang,  Hsiu-Ying Tseng,  Meng-Jia Li,  Yu-Ting Yu,  Hsiu-Chi Cheng,  Pei-Jane Tsai,  Yao-Jong Yang, 
  • First Published: 10 March 2025
Research Article
Open Access

Nomograms Based on Blood-Based Biomarkers for Predicting Prognosis in Locally Advanced Nasopharyngeal Carcinoma Patients

Sisi Wang,  Yuhua Feng,  Jie Ling,  Xiayan Zhao,  Yanming Hu,  Tao Hou,  Yangchun Xie, 
  • First Published: 10 March 2025
Research Article
Open Access

Deciphering the Interplay Among Inflammatory Bowel Disease, Gut Microbiota, and Inflammatory Biomarkers in the Risk of Colorectal Cancer

Chenyu Luo,  Bowen Tian,  Yueyang Zhou,  Jiahui Luo,  Qing Shang,  Si Yu,  Min Dai,  Yue Li,  Hongda Chen, 
  • First Published: 08 March 2025
Research Article
Open Access

1,25-D3 Protects Diabetic Brain Injury Through GLP-1R/PI3K/Akt Pathway by Experimental and Molecular Docking Studies

Ting Song,  Bin Wang,  Yutian Li,  Yingzhe Zhao,  Jian Li,  Yanqiang Wang,  Xiangling Li, 
  • First Published: 07 March 2025
Review Article
Open Access

Unveiling the Role of GRK2: From Immune Regulation to Cancer Therapeutics

Xizhuang Gao,  Dehuai Jing,  Yaowen Zhang,  Fengqin Zhu,  Yonghong Yang,  Guangxi Zhou, 
  • First Published: 05 March 2025
Research Article
Open Access

Interleukins-27 Aggravates Liver Injury by Impairing the Antimicrobial Response of Macrophages via the Promotion of Mitochondrial Dysfunction in the Context of Sepsis

Yuehua You,  Yuyan Li,  Lin Ye,  Fang Xu,  Jing Fan, 
  • First Published: 26 February 2025
Review Article
Open Access

Progress of ADAM17 in Fibrosis-Related Diseases

Suyan Yan,  Yaqi Zhao,  Yuyu Yang,  Baocheng Liu,  Wei Xu,  Zhenzhen Ma,  Qingrui Yang, 
  • First Published: 26 February 2025
Research Article
Open Access

Aeroallergen Sensitization Patterns and Related Factors in Children With Allergic Rhinitis in Guangzhou

Qingxiang Zeng,  Chao Yang,  Jinyuan Li,  Xiangqian Qiu,  Wenlong Liu, 
  • First Published: 25 February 2025
Research Article
Open Access

Taohong Siwu Decoction Combined With the LncRNA H19/miR-675-5p Axis Repairs Limb Ischemia-Reperfusion Injury Through the Regulation of the Wnt3a/Ca2+ Signaling Pathway

Fuping Zhu,  Hui Liu,  Yinsheng Cao,  Bing Dai,  Hang Wu,  Yutong Zhu,  Wuping Li, 
  • First Published: 23 February 2025
Research Article
Open Access

In Vitro, In Vivo, and In Silico Investigation of Synbiotic-Mediated Activation of PPAR-α Curtails Nonalcoholic Steatohepatitis (NASH) in Wistar Rats by Inhibiting PNPLA3/SREBP1-c Lead Inflammatory Injury of Hepatic Cells

Dixa Sharma,  Dhara Patel,  Palash Mandal, 
  • First Published: 19 February 2025
Research Article
Open Access

Herbal Medicine Extracts Improve Motor Function by Anti-Inflammatory Activity in hSOD1G93A Animal Model

Eun Jin Yang,  Sun Hwa Lee, 
  • First Published: 12 February 2025
Review Article
Open Access

Systematic Review of Interleukin-35 in Endothelial Dysfunction: A New Target for Therapeutic Intervention

Kai Li,  Jie Feng,  Meng Li,  Leilei Han,  Yanqing Wu, 
  • First Published: 12 February 2025
Research Article
Open Access

Selenium Nanoparticles Decorated With Stevioside Potentially Attenuate Fructose Palmitate Induced Lipid Accumulation in HepG2 Cells

Shuai Li,  Hui Yang,  Wenjun Zhou,  Ruoting Wang,  Likang Li,  Changfa Zhang,  Jingyi Zhang,  Yingxin Liu,  Zhi Huang,  Guowei Li, 
  • First Published: 12 February 2025
Research Article
Open Access

Inhibition of SIK1 Alleviates the Pathologies of Psoriasis by Disrupting IL-17 Signaling

Dongxuan Huang,  Huimin Sun,  Lianhui Su,  Fan Yang,  Dongsheng Huang,  Hanchao Gao,  Mengtao Cao, 
  • First Published: 06 February 2025
Research Article
Open Access

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Research Article
Open Access

Elevated Type 2 Inflammatory Factors, Th2/Th1 Balanced Status, and Exosomes as a Marker of Severity in Chronic Actinic Dermatitis

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Research Article
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Trapa natans L. Extract Attenuates Inflammation and Oxidative Damage in Cisplatin-Induced Cardiotoxicity in Rats by Promoting M2 Macrophage Polarization

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METTL3/miR-192-5p/SCD1 Axis Regulates Lipid Metabolism to Affect T Cell Differentiation in Asthma

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Research Article
Open Access

Characteristics of Pediatric Allergic Rhinitis With Different Disease Severity

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Research Article
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Modified Gegen Qinlian Decoction Ameliorates DSS-Induced Colitis in Mice via the Modulation of NF-κB and Nrf2/HO-1 Pathways

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Research Article
Open Access

Gene Expression Signatures of Smoking and Acute Myocardial Infarction: A Blood Transcriptome Analysis

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Research Article
Open Access

Flavonoids of Tetrastigma hemsleyanum Diels et Gilg Against Acute Hepatic Injury by Blocking PI3K/AKT Signaling Pathway

Lingling Li,  Lianghui Zhan,  Xiaojun Wu,  Xuechun Jiang,  Jinbao Pu, 
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