• Issue

    Chronic Diseases and Translational Medicine: Volume 8, Issue 4

    i, 245-330
    December 2022

TABLE OF CONTENTS

Open Access

Issue Information

  • Page: i
  • First Published: 19 December 2023

REVIEWS

Open Access

Harnessing natural killer cells to develop next-generation cellular immunotherapy

  • Pages: 245-255
  • First Published: 02 August 2022
Harnessing natural killer cells to develop next-generation cellular immunotherapy

In this review, we highlight the latest progress in the CAR-NK cell-based immunotherapy. We also discuss major roadblocks facing the clinical translation of CAR-NK cell therapy, and present potential strategies to surmount these challenges.

Open Access

New insights into the pathogenesis and management of rheumatoid arthritis

  • Pages: 256-263
  • First Published: 21 September 2022
New insights into the pathogenesis and management of rheumatoid arthritis

In this study, we summarized new insights into the pathogenesis and management of rheumatoid arthritis and associated comorbidities, with a special focus on the 2021 update of the American College of Rheumatology (ACR) guideline for rheumatoid arthritis and key reports presented at the 2021 ACR convergence.

Open Access

Pathophysiology and therapeutic advances in myeloma bone disease

  • Pages: 264-270
  • First Published: 04 July 2022
Pathophysiology and therapeutic advances in myeloma bone disease

Pathophysiology and main treatment options for myeloma bone disease.

Open Access

Epidemiology of biopsy-proven glomerular diseases in Chinese children: A scoping review

  • Pages: 271-280
  • First Published: 28 September 2022
Epidemiology of biopsy-proven glomerular diseases in Chinese children: A scoping review

Composition of major glomerular diseases in different age groups among children in China. Subgroup analysis of age was performed in N = 22,397 pediatric cases.

ORIGINAL ARTICLES

Open Access

Integrated statistical and machine learning analysis provides insight into key influencing symptoms for distinguishing early-onset type 2 diabetes

  • Pages: 281-295
  • First Published: 31 July 2022
Integrated statistical and machine learning analysis provides insight into key influencing symptoms for distinguishing early-onset type 2 diabetes

Workflow schematic of the data set characterization and classification analysis conducted in this study.

Open Access

Countrywide cardiovascular disease prevention and control in 49 countries with different socio-economic status

  • Pages: 296-304
  • First Published: 29 June 2022
Countrywide cardiovascular disease prevention and control in 49 countries with different socio-economic status

Age-standardized cardiovascular disease mortality rate per 100,000 population in countries with different levels of socioeconomic development, both sexes, 2000–2016.

Open Access

Changes in body composition in relation to estimated glomerular filtration rate and physical activity in predialysis chronic kidney disease

  • Pages: 305-313
  • First Published: 17 September 2022
Changes in body composition in relation to estimated glomerular filtration rate and physical activity in predialysis chronic kidney disease

Stage-wise prevalence of body composition abnormalities in predialysis chronic kidney disease.