Highlights

• Recommendations from current guidelines of blood pressure (BP) management differ a great deal, especially BP thresholds for initiation of antihypertensive drug therapy and BP treatment targets in people with and without diabetes.
• High-level evidence from high-quality clinical studies is urgently needed to settle uncertainties on BP management recommendations.

Highlights

• Low 50-g glucose challenge test (50-g GCT) values may be an early indicator for SGA neonates, and physicians should be cautious especially with regard to values less than 89.5 mg/dL.

Highlights

• In this very large cohort of 530 pregnancies in women with type 1 diabetes mellitus, we found that high prepregnancy glycosylated hemoglobin (HbA1c) is a predictor for suboptimal glycemic control during pregnancy and that HbA1c only decreases until midpregnancy and then plateaus.
• In addition, a very high prepregnancy HbA1c is associated with shorter gestational length and lower birthweight z score, which is contrary to the common assumption of poor glycemic control leading to higher birthweight.

Highlights

• The burden of noncommunicable diseases (NCDs) attributable to high fasting plasma glucose (HFPG) has increased significantly since 1990.
• Men and the elderly have a heavier burden of NCDs caused by HFPG.
• A higher burden of HFPG was found to be associated with a lower sociodemographic index.

Highlights

• High luteinizing hormone (LH) levels are positively associated with established type 2 diabetic kidney disease (DKD) among Chinese men and postmenopausal women.
• The positive associations between LH and macroalbuminuria risk were independent of age, diabetes duration, or other metabolic factors.
• The increase of circulating LH may be a promising clinical factor for identifying established DKD.

Highlights

• Type 2 diabetes mellitus is associated with impaired memory but not with verbal fluency.
• The association between diabetes and impaired memory becomes not significant by combining undiagnosed and nondiabetics in the same category.
• Including undiagnosed diabetics and diabetics in the same category attenuates the association between diabetes and impaired memory.

Highlights

• There are ~ 2-fold increased odds of severe coronavirus disease 2019 (COVID-19) and a ~ 2-fold increased risk of odds of mortality in patients with history of diabetes mellitus compared to those without diabetes mellitus.
• Patients with a history of diabetes mellitus should be closely monitored if they get infected with COVID-19.

Results of meta-analysis showing association of diabetes mellitus with severity (Panel A) of disease and mortality (Panel B) in coronavirus disease 2019 (COVID-19) patients

Highlights

• In normoalbuminuric diabetic patients at low cardiovascular risk, the risk of transition from normo- to microalbuminuria is lower in women, despite the nonprotective effects of the angiotensin receptor blocker olmesartan.
• Additional methods of assessment of albuminuria in clinical studies (eg, measurements of albumin and creatinine excretion rate) should be implemented or the actually accepted higher urine albumin creatinine ratio (UACR) cutoff values for microalbuminuria in women reconsidered.