Highlights

• Adults with diabetes mellitus have a greater risk of fracture, venous thromboembolism, and sepsis than those without diabetes; the use of corticosteroids, even for short durations, increases this risk.
• Vitamin D mitigated the risk of fracture in patients with diabetes who used corticosteroids, and statins decreased the likelihood of hospitalization for sepsis in corticosteroid users with diabetes.
• Corticosteroids should be used with caution in patients with diabetes and mitigating factors should be considered.

Highlights

• Heparan sulfate significantly alleviates the inflammatory reaction and reduces cleaved interleukin (IL)-1β, IL-18, and tumor necrosis factor-α production.
• Suppression of the inflammatory reaction may be mediated via downregulation of the NLR family pyrin domain containing 3 (NLRP3) inflammasome and upregulation of proteinase inhibitor 9 and caspase-12.

Highlights

• The best model of care to retard diabetes kidney disease (DKD) in the clinic is currently underexplored.
• Multidisciplinary endocrinology and nephrology care in the DKD clinic is associated with a lower risk of end-stage renal disease.

Highlights

• Serum fetuin-B concentrations are positively correlated with intrahepatic triglyceride content.
• Fetuin-B was independently associated with an increased risk of insulin resistance in humans.
• The role of fetuin-B links liver fat accumulation to insulin resistance in humans.

Highlights

• This 24-week, Phase 3 double-blind placebo-controlled study assessed the safety and efficacy of dapagliflozin as add-on to insulin, with or without oral antihyperglycemic drugs, in Asian patients with inadequately controlled type 2 diabetes mellitus.
• Study results demonstrate that compared with placebo, dapagliflozin 10 mg as add-on to insulin, with or without oral antihyperglycemic drugs, significantly improved glycemic control and reduced body weight and blood pressure, without increased risk of hypoglycemia.

Highlights

• An automatic bolus calculator with automatic speech recognition may effectively improve postprandial glucose control in patients with type 1 diabetes (T1D).
• The VoiceDiab system may be useful in the treatment of patients with T1D on intensive insulin therapy.