Highlights

• The minor allele G for fetuin B (FETUB) rs4686434 was significantly associated with decreased intrahepatic triglyceride (IHTG) content.
• There was a significant joint effect between FETUB rs4686434 and patatin-like phospholipase domain containing 3 (PNPLA3) rs738409 on IHTG content.

Highlights

• There is clear consensus that population-specific obesity classification should be identified, but body mass index (BMI) cut-off points have not been determined for assessing diabetes risk in Chinese participants.
• This study found that age- and sex-specific BMI cut-off points for assessing Type 2 diabetes mellitus (T2DM) risk, but not a unit cut-off point for the whole population, should be considered in future T2DM risk assessments in a Chinese population.

Highlights

• Fasting blood glucose and HbA1c values do not match in almost 25% of people with type 2 diabetes mellitus (T2DM) in primary care practices.
• Our analysis shows that the odds of having discordant glucose and HbA1c values is related to characteristics of people with T2DM (including age, sex, diabetes duration, body mass index), glucose-lowering drug treatment, comorbidity (liver disease, hypertension, depression), and complications (neuropathy, retinopathy, low estimated glomerular filtration rate).

Highlights

• Despite the advent of newer agents for the management of diabetes, the number of people with diabetes hitting all clinical targets remains small.
• In this review we explore the role that communication plays in defining and achieving shared goals of importance to the health care provider–patient team. This dyad deals with acknowledging the complexity of diabetes management in the context of everyday life, and encourages the person with diabetes to take full ownership of their disease, thereby improving outcomes.

Highlights

• The present study is the first to assess cognitive functioning in a sample of Chinese pediatric patients with type 1 diabetes mellitus (T1DM).
• Greater exposure to hyperglycemia over time was associated with lower visuospatial perception.
• Early exposure to severe hypoglycemia had negative effects on visual memory.

Highlights

• Abnormal glucose regulation, determined by oral glucose tolerance tests, was independently associated with serum aryl hydrocarbon receptor (AhR) concentrations in subjects with no history of diabetes.
• Serum AhR concentrations were negatively associated with β-cell function, independent of several confounders, including insulin resistance.

Highlights

• This study has shown the benefits of pharmacists using the Simpler tool to make consistent, individualized, evidence-based interventions in the clinical management of patients with type 2 diabetes mellitus.
• Qualified pharmacists in community or hospital settings with or without prior formal diabetes training can be trained to use the tool to deliver quality diabetes care.
• The study findings may be generalized to studies that recruit participants with similar inclusion and exclusion criteria and with direct access to a prescriber.

Highlights

• Tin was detected in 86.8% of urine samples, and the median urinary tin concentration was 0.4 μg/L.
• Urinary tin concentration was associated with a higher risk of diabetes.