• Issue

    Echocardiography: Volume 42, Issue 3

    March 2025

ISSUE INFORMATION

Free Access

Issue Information

  • First Published: 04 March 2025

REVIEW

Open Access

Functional Mitral Valve Regurgitation, Pathophysiology, Leaflet ReModeling, and the Role of Imaging

  • First Published: 25 February 2025
Functional Mitral Valve Regurgitation, Pathophysiology, Leaflet ReModeling, and the Role of Imaging

Functional mitral regurgitation (FMR) is a complex left ventricle (LV) and left atrium (LA) disorder with a multifactorial etiology. Regional and global LV dysfunction, extent and location of fibrotic myocardium and annulus enlargement are the leading causes of valve regurgitation. Echocardiography and CMR have a critical role in the comprehensive assessment of FMR.

INVITED REVIEW

Diagnostic and Prognostic Value of RV Strain Defined as RV/LV Ratio on Chest CT in Acute Pulmonary Embolism: A Systematic Review

  • First Published: 03 March 2025
Diagnostic and Prognostic Value of RV Strain Defined as RV/LV Ratio on Chest CT in Acute Pulmonary Embolism: A Systematic Review

The objective of the study was to conduct a comprehensive review of the diagnostic and prognostic value of CT RV/LV ratio to provide a practical, reproducible, and evidence-based cutoff and measurement methodology to identify RV dysfunction (“strain”) in acute PE.

REVIEW

Multimodality Imaging and Immune-Related Adverse Events During Immune Checkpoint Inhibitors Treatment: Where Do We Stand?

  • First Published: 03 March 2025
Multimodality Imaging and Immune-Related Adverse Events During Immune Checkpoint Inhibitors Treatment: Where Do We Stand?

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy, significantly improving survivals across various malignancies, but may be associated with various types of immune-related adverse events (irAEs). Multimodality imaging, including transthoracic echocardiography, cardiac CT, cardiovascular magnetic resonance, and nuclear cardiology are fundamental diagnostic tools for the early detection of cardiotoxicity and monitoring.

INVITED REVIEW

Advancements in Computed Tomography Angiography for Pulmonary Embolism Assessment

  • First Published: 03 March 2025
Advancements in Computed Tomography Angiography for Pulmonary Embolism Assessment

Advancements in computed tomography pulmonary angiography (CTPA): Innovations in spectral CT-derived reconstruction algorithms and integration of artificial intelligence (AI) and radiomics for enhanced diagnosis and risk stratification of pulmonary embolism.

CASE IMAGE

Total Anomalous Pulmonary Venous Drainage Caused by Malposition of Septum Primum in Adults

  • First Published: 03 March 2025
Total Anomalous Pulmonary Venous Drainage Caused by Malposition of Septum Primum in Adults

• MSP has primarily been reported in fetuses or children, with only one case of adult MSP with PAPVD previously reported in 2022.

The case we report is about an adult with TAPVD which caused by MSP. There are no similar reports so far. .

ORIGINAL ARTICLE

Open Access

Myocardial Dysfunction and Risk of Long COVID in Patients Recovered From Mild and Moderate COVID-19

  • First Published: 03 March 2025
Myocardial Dysfunction and Risk of Long COVID in Patients Recovered From Mild and Moderate COVID-19

Patients who recovered from COVID-19 and presented to our hospital for echocardiography due to cardiovascular symptoms during the Omicron surge were retrospectively reviewed. Myocardial strains of 546 such recovered patients, both pre- and post-infection, were compared with those of COVID-19-free controls. Results indicated that post-infection, left ventricular global longitudinal strain (LVGLS) stayed constant, yet left atrial strain (LAS) and regional left ventricular longitudinal strain (LVLS) declined. After a 1-year follow-up, 16.48% of patients had persistent cardiovascular symptoms, which were linked to LA strain and basal inferoseptal LVLS.

ORIGINAL ARTICLE

Open Access

Echocardiographic Parameters of Right Ventricular Size and Function Associated With Right Heart Failure After Durable Left Ventricular Assist Device Implantation—A Systematic Review and Meta-Analysis

  • First Published: 04 March 2025

Echocardiographic Parameters of Right Ventricular Size and Function Associated With Right Heart Failure After Durable Left Ventricular Assist Device Implantation—A Systematic Review and Meta-Analysis

TTE parameters of baseline RV function should not be used in patients with LVADs due to device-related changes in physiology. TAPSE and RVEDD are promising prognostic markers in screening for development of RV failure after LVAD implantation.

LIST OF REVIEWERS

Open Access

Top reviewers 2024 echo

  • First Published: 06 March 2025

ORIGINAL ARTICLE

Predicting the Need for Pulmonary Venous Reintervention in Total Anomalous Pulmonary Venous Connection: The Role of Preoperative Echocardiographic Metrics

  • First Published: 06 March 2025
Predicting the Need for Pulmonary Venous Reintervention in Total Anomalous Pulmonary Venous Connection: The Role of Preoperative Echocardiographic Metrics

In patients with total anomalous pulmonary venous connection (TAPVC), preoperative echocardiographic metrics were collected and used to calculate the pulmonary venous variability index (PVVI). PVVI ≤ 0.5 was the only measure predictive of catheter-based or surgical pulmonary venous reintervention after initial repair; however, this association was lost when single ventricle status and TAPVC subtype were incorporated into multivariate analysis .

CASE IMAGE

Right Aortic Arch With Kommerell Diverticulum and a Rare Type of Isolated Left Subclavian Artery

  • First Published: 10 March 2025
Right Aortic Arch With Kommerell Diverticulum and a Rare Type of Isolated Left Subclavian Artery

We reported a 10-year-old boy with a rare type isolated left subclavian artery. The patient's left subclavian artery evolved from stenosis to atresia, resulting in the subclavian steal syndrome.

ORIGINAL ARTICLE

Feasibility Study of Applying the Modified Hahn Nomenclature for Tricuspid Valve Leaflet Classification in Transthoracic Echocardiography Using the Subxiphoid Short-Axis View

  • First Published: 11 March 2025
Feasibility Study of Applying the Modified Hahn Nomenclature for Tricuspid Valve Leaflet Classification in Transthoracic Echocardiography Using the Subxiphoid Short-Axis View

By applying the adapted Hahn tricuspid valve nomenclature, we explored whether the subxiphoid short-axis view (SSAV) can effectively apply this classification.

CASE IMAGE

Multimodality Imaging Approach for a Transient Ischemic Stroke as a First Manifestation of Papillary Fibroelastoma

  • First Published: 11 March 2025
Multimodality Imaging Approach for a Transient Ischemic Stroke as a First Manifestation of Papillary Fibroelastoma

Take home messages

1. Despite being considered a benign tumor, the high reported incidence of embolic events increasingly warrants surgical resection, regardless of size, especially in patients with a history of cardiovascular risk factors.

2. Multimodal imaging evaluation plays a crucial role in distinguishing intracardiac masses, relying on the physician's ability to discern characteristic findings. Proper assessment leads to appropriate management decisions based on suggestive findings.

CASE IMAGE

Hydrops Fetalis Secondary to Left Ventricle Diastolic Collapse Caused by Giant Rhabdomyoma: Utility of 4D STIC and Fetal Heart Quantification Techniques

  • First Published: 11 March 2025
Hydrops Fetalis Secondary to Left Ventricle Diastolic Collapse Caused by Giant Rhabdomyoma: Utility of 4D STIC and Fetal Heart Quantification Techniques

This case image illustrates the utility of fetal HQ and 4D STIC echocardiography in a 24-week gestation fetus in understanding the hemodynamics responsible for the fetal heart failure due to LV rhabdomyoma.

ORIGINAL ARTICLE

A New Method Using the Four-Chamber View to Identify Fetuses With Subsequently Confirmed Postnatal Aortic Coarctation

  • First Published: 12 March 2025
A New Method Using the Four-Chamber View to Identify Fetuses With Subsequently Confirmed Postnatal Aortic Coarctation

From a study of 54 fetuses with Coarctation of the Aorta and 54 with a false-positive diagnosis of Coarctation of the Aorta we developed a calculator that only required 8 end-diastolic measurements from the 4-chamber view to predict Coarctation of the Aorta with a Sensitivity of 98.15% and specificity of 98.15%.

Changes in Left Ventricular Function Assessed by 3D Echocardiography During Severe Central Hypovolemia in Healthy Humans

  • First Published: 12 March 2025
Changes in Left Ventricular Function Assessed by 3D Echocardiography During Severe Central Hypovolemia in Healthy Humans

The purpose of the present study was to clarify the changes of left ventricular twisting and untwisting motions during severe central hypovolemia using 3D echocardiography. The present findings by three-dimensional (3D) echocardiography indicate that in healthy humans, LV twist/untwist function is enhanced during severe central hypovolemia. On the other hand, conventional echocardiographic indices for LV contractility, diastolic relaxation, and myocardial strain deteriorated. In particular, E/e’ paradoxically increased during severe central hypovolemia. These findings suggest that to accurately assess hemodynamic conditions, measurement of twist/untwist function may be useful in addition to conventional echocardiographic indices.

Right Atrial Function and Right Ventricular Diastolic Function and Their Relation With Exercise Capacity in OSAS

  • First Published: 16 March 2025

Right Atrial Function and Right Ventricular Diastolic Function and Their Relation With Exercise Capacity in OSAS

We found that patients with OSAS exhibit reduced right ventricular diastolic function and right atrial reservoir strain (RARS). Additionally, the TV E/e′ (Figure A) and RARS (Figure B) are correlated with peak VO2 in these patients, suggesting that the decline in exercise capacity in OSAS patients is related to RV diastolic function and RA function.

Open Access

To Each Imaging Modality, Their Own MAD

  • First Published: 19 March 2025

To Each Imaging Modality, Their Own MAD

Mitral annular disjunction (MAD) of limited extent is common on CMR and more than two thirds of patients showing MAD on CMR did not have MAD on TTE. Methodological discrepancies impact MAD assessment .

Impaired Left Atrial Reservoir Strain Causes Exercise-Induced Pulmonary Hypertension in Patients With Preserved Left Ventricular Ejection Fraction

  • First Published: 20 March 2025

Impaired Left Atrial Reservoir Strain Causes Exercise-Induced Pulmonary Hypertension in Patients With Preserved Left Ventricular Ejection Fraction

Left atrial (LA) reservoir strain at rest is independently associated with exercise-induced pulmonary hypertension (EIPH) and has an important factor in predicting patients with EIPH. Patients with LA reservoir strain ≤21% have an increased risk of heart failure (HF) events.

Evaluation of Segmental Myocardial Work and Exercise Tolerance in Hypertension Patients With Left Ventricular Remodeling Through Stress Echocardiography

  • First Published: 21 March 2025
Evaluation of Segmental Myocardial Work and Exercise Tolerance in Hypertension Patients With Left Ventricular Remodeling Through Stress Echocardiography

MW parameters reflect the contractile force under hemodynamic overload, offering a more compelling perspective for evaluating cardiac function, including segments value. GWI-rest and ΔGWI provide powerful incremental value in independent associations with exercise capacity.