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ISSUE INFORMATION
ORIGINAL ARTICLE
Evaluation of Right and Left Ventricular Deformation Analysis in İdiopathic Right Bundle Branch Block by Speckle Tracking Echocardiography
- First Published: 28 January 2025

This study aims to examine the right and left ventricular functions in patients with idiopathic right bundle branch block (RBBB) and compare them to those in a healthy control group. Our findings show that idiopathic RBBB significantly affects the longitudinal strain and synchronization of both the left and right ventricles.
Effects of Isoproterenol Administration in Dobutamine Stress Echocardiography
- First Published: 28 January 2025

This study showed that adjunctive isoproterenol in dobutamine stress echocardiography (DSE) with or without atropine increases the number of diagnostic studies with no significant increase in side effects or mortality. The most common side effects of combined infusion were nausea, premature ventricular contractions, hypertension, and hypotension.
Diagnostic Utility of Relative Apical Sparing Index in Cardiac Amyloidosis Subtypes: A Comparative Study of Immunoglobulin Light Chain and Transthyretin Amyloid Cardiomyopathy
- First Published: 28 January 2025
REVIEW
Left Atrial Markers in Diagnosing and Prognosticating Non-Ischemic Cardiomyopathies: Ready for Prime Time?
- First Published: 28 January 2025

The assessment of left atrial size and mechanics, with speckle-tracking echocardiography (STE) or magnetic-resonance feature tracking (CMR-FT), is very informative on preclinical stages of nonischemic cardiomyopathies (NICM), the stage of disease progression and for prognostication. In this article, we highlight the studies that investigated the value of these parameters .
ORIGINAL ARTICLE
Fetal Cardiac Function and Remodeling in In Vitro Fertilization Pregnancies: A Tertiary Center Experience
- First Published: 28 January 2025
CASE IMAGE
Multimodality Imaging of Bilateral Ductus Arteriosus in a Patient With Complex Heterotaxy and a Univentricular Heart
- First Published: 06 February 2025

The images presented show heterotaxy (right atrial isomerism), mitral and pulmonary valve atresia, single ventricle physiology, non-confluent branch pulmonary arteries supplied by ipsilateral ductus, and a large VSD. Non-confluent branch pulmonary arteries which are supplied by bilateral ducts are a rare cardiac anomaly which is illustrated by multimodality imaging in this patient.
COMMENTARY
Valve It Right? Can Transthoracic Imaging Prevent CIED-Induced Tricuspid Regurgitation?
- First Published: 07 February 2025
EDITORIAL
Left Ventricular Myocardial Work Indices Post-TAVR: A New Paradigm for Prognosis in Aortic Stenosis
- First Published: 07 February 2025
CASE IMAGE
Right Ventricular Outflow Tract Hemangioma: A Rare Cause of Obstruction
- First Published: 07 February 2025
ORIGINAL ARTICLE
Increased Afterload in Patients With Acute Reduction in Left Ventricular Ejection Fraction Following Mitral Valve Transcatheter Edge-to-Edge Repair
- First Published: 08 February 2025

Right panels: Linear regression between ΔLVEF and Δtotal SV (upper panel), and ΔEa and Δtotal SV (lower panel). Left panel: Pressure–volume loops before and after TEER according to acute reduction in LVEF. Ea, arterial elastance; LVEF, left ventricular ejection fraction; SV, stroke volume; TEER, transcatheter mitral valve edge-to-edge repair.
INVITED REVIEW
Artificial Intelligence Applications in Cardiac CT Imaging for Ischemic Disease Assessment
- First Published: 10 February 2025

AI algorithms are utilized in various areas of cardiac computed tomography, such as coronary artery calcium (CAC) scoring, coronary stenosis evaluation, atherosclerotic plaque assessment, CT-derived fractional flow reserve (FFRct), myocardial computed tomography perfusion (CTP), and epicardial adipose tissue analysis. Implementing AI in clinical practice can alleviate the radiologists’ workload and improve diagnostic accuracy, risk stratification, and outcome prediction. .
Value of Ultrahigh-Resolution Photon-Counting Detector Computed Tomography in Cardiac Imaging
- First Published: 13 February 2025

Photon-counting detector computed tomography (PCD-CT) represents a big leap forward in non-invasive cardiac assessment over conventional standard resolution energy-integrating detector (EID)-CTs. This new detector technology enables ultrahigh-resolution (UHR) imaging at resolutions of up to 0.2 mm. Additional filtering of electronic noise and photon energy discrimination allow PCD-CT to image patients with a high calcium burden, assess in-stent patency, improve stenosis quantification and accuracy, as well as the visualization of small diameter vessels. .
ORIGINAL ARTICLE
Reference Ranges of Left Ventricular Global Longitudinal Strain by Contemporary Vendor-Neutral Echocardiography Software in Healthy Subjects
- First Published: 14 February 2025
REVIEW
Uncommon Causes of Pulmonary Hypertension With Associated Cardiomyopathy: Computed Tomography and Magnetic Resonance Imaging of Cardiothoracic Manifestations
- First Published: 14 February 2025

Pulmonary hypertension (PH) is a disease characterized by pathologically increased pressure in the pulmonary arteries, possibly associated in specific clinical contexts with cardiomyopathies, pathologies characterized by structural and functional anomalies of the myocardium. The diagnostic work-up of these patients includes the use of computed tomography (CT) and cardiovascular magnetic resonance imaging (CMR), two imaging techniques that provide also information useful for therapeutic management and prognostic evaluation. The aim of this review is to describe the most relevant cardiothoracic findings of uncommon pathologies characterized by associated PH and cardiomyopathy, namely sarcoidosis, systemic sclerosis (SSc), and chronic kidney disease (CKD).
ORIGINAL ARTICLE
Pre-Operative Atrial Deformation Indices Predict Post-Operative Atrial Fibrillation in Patients Undergoing Lung Resection Surgery
- First Published: 14 February 2025

Reduced left atrial strain metrics are more specific and sensitive than conventional demographics and standard echocardiography in predicting post-operative atrial fibrillation. Preoperative LA imaging might aid with identifying patients undergoing lung resection who are high-risk and benefit from prophylactic therapy.
INVITED REVIEW
Advanced Computed Tomography and Magnetic Resonance Imaging in Ischemic and Nonischemic Cardiomyopathies
- First Published: 14 February 2025

(1) Coronary CTA multiplanar reformat showing severe stenosis by a noncalcified plaque in the right coronary artery (RCA). (2) Cardiac MRI (CMR) short-axis and four-chamber views of the left ventricle (LV) show midwall linear late gadolinium enhancement (LGE) in the LV septum corresponding to FDG-avid uptake on cardiac PET CT. (3) CMR in a young woman with shortness of breath shows LGE in mass-like hypertrophic cardiomyopathy (arrow), previously undiagnosed. Coronary CTA and CMR are vital and complementary tools in the diagnosis, risk stratification, prognosis, and therapeutic decision making of ischemic and nonischemic cardiomyopathies.
CT and MR Imaging of Cardiomyopathies in Clinical Practice–An Approach After an Abnormal Echocardiogram or Electrocardiogram
- First Published: 18 February 2025

The main roles of different cardiac MR sequences and cardiac CT in the approach to cardiomyopathies in clinical practice. AFD, Anderson–Fabry disease; ARVC, arrhythmogenic right ventricular cardiomyopathy; CMR, cardiac magnetic resonance; DCM, dilated cardiomyopathy; ECV, extracellular volume; HCM, hypertrophic cardiomyopathy; MACE, major adverse cardiovascular events; STIR, short Tau inversion recovery.
REVIEW
Acute Myocarditis and Inflammatory Cardiomyopathies: Insights From Cardiac Magnetic Resonance Findings
- First Published: 18 February 2025

The pathogenesis and progression of myocardial inflammation involve a multiphase process driven by genetic, epigenetic, autoimmune, and environmental factors. Inflammation establishes a self-perpetuating “vicious cycle”, causing progressive myocardial damage. In AM, direct causative agents and indirect autoimmune mechanisms are reflected in T2 and T1 criteria of the LLC. While most patients recover fully, some develop localized fibrotic scarring or diffuse fibrotic replacement, evidenced by subepicardial/mid-wall LGE or increased native T1 mapping and ECV values. In a minority, inflammation may persist or recur, leading to progressive fibrotic scarring. Finally, chronic inflammatory processes can result in progression toward DCM. AM, acute myocarditis; DCM, dilated cardiomyopathy; ECV, extra-cellular volume; I-CMP, inflammatory cardiomyopathy; LGE, late gadolinium enhancement; LLC, Lake-Louise criteria.
INVITED REVIEW
Myocardial Characterization on CT: Late Iodine Enhancement and Extracellular Volume
- First Published: 18 February 2025

In the recent years, cardiac computed tomography (CCT) emerged as a valuable alternative to cardiac magnetic resonance (CMR) for the characterization of myocardial fibrosis, particularly focal and interstitial type enabling CCT to complement or substitute CMR in specific clinical scenarios. This review highlights the key technical aspects and the clinical scenarios where myocardial characterization in CT is beneficial.
REVIEW
Value of Advanced Cardiac CTA in Clinical Assessment of Hypertrophic Cardiomyopathy: A Literature Review and Practical Implications
- First Published: 18 February 2025

Cardiac CTA (CCTA) has great value in the clinical evaluation of hypertrophic cardiomyopathy (HCM), a genetic cardiac disease that can potentially cause sudden cardiac death. CCTA should be used as a primary imaging tool in HCM assessment given its multifaceted role, including in-depth evaluation of the cardiac function and anatomy in addition to its utility in preplanning before HCM-related therapeutic intervention. Abbreviations: AO = aorta, IVS = interventricular septum, LA = left atrium, LAD = left anterior descending artery, LCX = left circumflex, LV = left ventricle, RCV = right ventricle.
COMMENTARY
Myocardial Work and Dynamic Exercise Stress: Opening a New Window Into Diagnosis of Hypertensive Heart Disease
- First Published: 19 February 2025
ORIGINAL ARTICLE
Left Ventricular Outflow Indices in Chronic Systolic Heart Failure: Thresholds and Prognostic Value
- First Published: 19 February 2025

In patients with heart failure and LVEF < 50%, left ventricular outflow tract-velocity time integral (LVOT-VTI) had the best reproducibility compared to other parameters describing forward flow. The parameter was also associated with cardiovascular mortality in multivariate Cox analysis. The combination of impaired LVOT-VTI with TAPSE/PASP showed the worst survival.
COMMENTARY
“Better Is the Enemy of Good”: The Deleterious Effects of Supra-Normal Left Ventricular Ejection Fraction
- First Published: 19 February 2025
ORIGINAL ARTICLE
Clinical Outcomes of Intracardiac Echocardiography-Guided Radiofrequency Catheter Ablation for Atrial Fibrillation: A Retrospective Study
- First Published: 21 February 2025