REVIEW
Value of Advanced Cardiac CTA in Clinical Assessment of Hypertrophic Cardiomyopathy: A Literature Review and Practical Implications
Rabih Touma,
Anisha R. Pareddy,
Aiden Abidov,
Corresponding Author
Rabih Touma
Department of Medicine/Division of Cardiology, Wayne State University School of Medicine, Detroit, Michigan, USA
Department of Medicine/Division of Cardiology, John D. Dingell VA, Medical Center, Detroit, Michigan, USA
Correspondence: Rabih Touma ([email protected])
Search for more papers by this authorAnisha R. Pareddy
Department of Medicine/Division of Cardiology, Wayne State University School of Medicine, Detroit, Michigan, USA
Department of Medicine/Division of Cardiology, John D. Dingell VA, Medical Center, Detroit, Michigan, USA
Search for more papers by this authorAiden Abidov
Department of Medicine/Division of Cardiology, Wayne State University School of Medicine, Detroit, Michigan, USA
Department of Medicine/Division of Cardiology, John D. Dingell VA, Medical Center, Detroit, Michigan, USA
Search for more papers by this authorRabih Touma,
Anisha R. Pareddy,
Aiden Abidov,
Corresponding Author
Rabih Touma
Department of Medicine/Division of Cardiology, Wayne State University School of Medicine, Detroit, Michigan, USA
Department of Medicine/Division of Cardiology, John D. Dingell VA, Medical Center, Detroit, Michigan, USA
Correspondence: Rabih Touma ([email protected])
Search for more papers by this authorAnisha R. Pareddy
Department of Medicine/Division of Cardiology, Wayne State University School of Medicine, Detroit, Michigan, USA
Department of Medicine/Division of Cardiology, John D. Dingell VA, Medical Center, Detroit, Michigan, USA
Search for more papers by this authorAiden Abidov
Department of Medicine/Division of Cardiology, Wayne State University School of Medicine, Detroit, Michigan, USA
Department of Medicine/Division of Cardiology, John D. Dingell VA, Medical Center, Detroit, Michigan, USA
Search for more papers by this authorFirst published: 18 February 2025
Funding: The authors received no specific funding for this work.
ABSTRACT
Hypertrophic cardiomyopathy (HCM) is a common inherited cardiac anomaly with a potentially unfavorable clinical outcome. The essential role of multimodality imaging in HCM is well recognized by major professional cardiac imaging societies and has been incorporated into the HCM clinical practice guidelines. Appropriate utilization of cardiac imaging tools is cardinal for accurate diagnosis and appropriate management for HCM patients to mitigate their lifelong risk of adverse events. Echocardiography is the imaging modality of choice for clinical diagnosis of HCM. Cardiac magnetic resonance (CMR) and coronary computed tomography angiogram (CCTA) offer complementary practical information for an inclusive evaluation in such patients. CCTA provides a thorough analysis of the cardiac anatomy and function that is paramount in HCM clinical decision-making. This review summarizes the utility of CCTA in the clinical assessment of patients with HCM. It outlines the multi-role of CCTA in HCM, including the quantification of cardiac parameters, myocardial tissue characterization, left ventricular (LV) functional analysis, the definition of cardiac and coronary arteries (CA) anatomy, and the provision of a roadmap for septal reduction therapies (SRT), mitral valve (MV) intervention, and atrial fibrillation (AF) ablation.
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