• Issue

    Reproductive Medicine and Biology: Volume 17, Issue 2

    105-216
    April 2018

ISSUE INFORMATION

Open Access

Issue Information

  • Pages: 105-106
  • First Published: 16 April 2018

REVIEW ARTICLES

Open Access

Generation of germ cells from pluripotent stem cells in mammals

  • Pages: 107-114
  • First Published: 10 December 2017
Generation of germ cells from pluripotent stem cells in mammals

Mammalian PGC development in vivo and in vitro, have been studied primarily using the mouse model as a template to study PGCs specification in other mammals including humans, porcine and bovine.The growing body of published works reveal similarities as well as differences in PGCs establishment in and between mouse and human

ORIGINAL ARTICLES

Open Access

Effectiveness of high-dose i.v. immunoglobulin therapy for pregnant women with aspirin–heparin-resistant secondary antiphospholipid syndrome

  • Pages: 149-154
  • First Published: 01 January 2018
Effectiveness of high-dose i.v. immunoglobulin therapy for pregnant women with aspirin–heparin-resistant secondary antiphospholipid syndrome

High dose intravenous immunoglobulin (HIVIg) therapy (20 g/day, 5 days) was performed in eight pregnancies from five women with antiphospholipid syndrome (APS) who had a history of pregnancy failure despite receiving low dose aspirin plus unfractionated heparin therapy. Five of the eight pregnancies ended in live birth. HIVIg therapy might be beneficial as an immune modifier for pregnant women with APS.

Open Access

Decreased carbonyl reductase 1 expression promotes tumor growth via epithelial mesenchymal transition in uterine cervical squamous cell carcinomas

  • Pages: 173-181
  • First Published: 25 January 2018
Decreased carbonyl reductase 1 expression promotes tumor growth via epithelial mesenchymal transition in uterine cervical squamous cell carcinomas

Decreased CBR1 expression promotes tumor growth via epithelial mesenchymal transition in uterine cervical squamous cell carcinomas.

Open Access

Association of genetic variants of PD1 with recurrent pregnancy loss

  • Pages: 195-202
  • First Published: 23 March 2018
Association of genetic variants of PD1 with recurrent pregnancy loss

Variations of the PD1 gene were confirmed to be risk factors for RPL. However, no predictive effect of the PD1 risk allele on subsequent pregnancy outcome have been identified.

CASE REPORT

Open Access

Microdissection testicular sperm extraction in five Japanese patients with non-mosaic Klinefelter's syndrome

  • Pages: 209-216
  • First Published: 08 March 2018
Microdissection testicular sperm extraction in five Japanese patients with non-mosaic Klinefelter's syndrome

For non-mosaic Klinefelter syndrome with azoospermia, Micro-TESE is an effective sperm collection method.

In addition, in this study, we experienced a case with partial deletion of Azoospermia factor b in a nonmosaic Kleinfelter syndrome.

Even in Klinefelter's syndrome it is important to search for the Azoospermia factor microdeletion for prediction of sperm acquisition.