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ARTICLE
Open Access

oa

Loss of CYLD promotes splenic marginal zone lymphoma
Athanasios Pseftogas, Jessica Bordini, Silvia Heltai, Ferdinando Bonfiglio, Georgios Gavriilidis, Vasileios Vasileiou, Sofoklis Keisaris, Daniela Belloni, Caterina Taccetti, Pamela Ranghetti, Eleonora Perotta, Michela Frenquelli, Uday Aditya Sarkar, Elisa Albi, Francesca Martini, Emmanuela Sant'Antonio, Fabrizio Mavilia, Fotis Psomopoulos, Manasori Daibata, José Ángel Martínez Climent, George Mosialos, Davide Rossi, Alessandro Campanella, Lydia Scarfò, Kostas Stamatopoulos, Konstantinos Xanthopoulos, Paolo Ghia,

First published: 17 March 2025

Graphical Abstract
ARTICLE
Open Access

oa

Age- and gender-specific molecular characteristics of diffuse large B-cell lymphoma: Results from clinical trials of the DSHNHL/GLA
Katrin S. Kurz, Sophia Steinlein, Markus Kreuz, Marita Ziepert, Annette M. Staiger, Thomas F. E. Barth, Peter Möller, Heinz-Wolfram Bernd, Alfred C. Feller, Julia Richter, Wolfram Klapper, Harald Stein, Sylvia Hartmann, Martin-Leo Hansmann, Lorenz Trümper, Markus Loeffler, Norbert Schmitz, Andreas Rosenwald, German Ott, Heike Horn, DSHNHL/GLA,

First published: 07 March 2025

Graphical Abstract
LETTER
Open Access

oa

Salvage treatment after covalent BTKi failure: An unmet need in clinical practice in Waldenstrom macroglobulinemia
Anna Maria Frustaci, Arianna Zappaterra, Andrea Galitzia, Andrea Visentin, Michele Merli, Rita Rizzi, Isacco Ferrarini, Simone Ferrero, Vanessa Innao, Claudia Baratè, Pierluigi Zinzani, Benedetta Puccini, Francesco Autore, Monica Tani, Angela Ferrari, Gioacchino Catania, Maura Nicolosi, Raffaella Pasquale, Marina Motta, Roberta Murru, Silvia Gambara, Francesca Rezzonico, Marzia Varettoni, Emanuele Cencini, Enrico Lista, Nicolò Danesin, Bianca Maria Granelli, Marina Deodato, Francesco Piazza, Alessandra Tedeschi,

First published: 20 February 2025
ARTICLE
Open Access

oa

Outcomes of patients with relapsed or refractory primary mediastinal B-cell lymphoma treated with anti-CD19 CAR-T cells: CARTHYM, a study from the French national DESCAR-T registry
Jean Galtier, Charles Mesguich, Pierre Sesques, Vivien Dupont, Emmanuel Bachy, Roberta Di Blasi, Catherine Thieblemont, Thomas Gastinne, Guillaume Cartron, Gabriel Brisou, François-Xavier Gros, Justine Decroocq, Franck Morschhauser, Marie-Thérèse Rubio, Laurianne Drieu La Rochelle, Fabien Le Bras, Sylvain Carras, Adrien Chauchet, Jacques-Olivier Bay, Magalie Joris, Mickael Loschi, Aline Tanguy-Schmidt, Alexandra Marquet, Vincent Camus, Steven Le Gouill, Roch Houot, Krimo Bouabdallah,

First published: 18 February 2025

Graphical Abstract

$Outcomes of patients with relapsed or refractory primary mediastinal B-cell lymphoma treated with anti-CD19 CAR-T cells: CARTHYM, a study from the French national DESCAR-T registry$
ARTICLE
Open Access

oa

Single-cell DNA and surface protein characterization of high hyperdiploid acute lymphoblastic leukemia at diagnosis and during treatment
Margo Aertgeerts, Sarah Meyers, Olga Gielen, Jochen Lamote, Barbara Dewaele, Mercedeh Tajdar, Johan Maertens, Jolien De Bie, Kim De Keersmaecker, Nancy Boeckx, Lucienne Michaux, Anne Uyttebroeck, Sofie Demeyer, Heidi Segers, Jan Cools,

First published: 11 February 2025

Graphical Abstract
LETTER
Open Access

oa

Chimeric antigen receptor T-cell therapy outcomes in T cell/histiocyte-rich large B-cell lymphoma and subsequent treatment strategies after disease progression: A GELTAMO/GETH study
Mariana Bastos-Oreiro, Gloria Iacoboni, Víctor N. Garcés, Ana C. Caballero, Nuria Martínez, Javier Delgado, Aitana Balaguer, Mi Kwon, Sonia Gonzalez de Villambrosia, Rafael Hernani, Ana Jimenez-Ubieto, Rebeca Bailen, Izaskun Zaberio, Alejandro Martín García-Sancho, Pere Barba,

First published: 04 February 2025
ARTICLE
Open Access

oa

Dynamic evolution of TCF3-PBX1 leukemias at the single-cell level under chemotherapy pressure
Mira Kusterer, Mari Lahnalampi, Minna Voutilainen, Alexandra Brand, Sandra Pennisi, Johana Norona, Gaia Gentile, Heike Herzog, Gabriele Greve, Michael Lübbert, Mikko Sipola, Emma Kaartinen, Roman Sankowski, Marco Prinz, Saskia Killmer, Marilyn S. Lago, Bertram Bengsch, Stepan R. Cysar, Konrad Aumann, Martin Werner, Justus Duyster, Olli Lohi, Merja Heinäniemi, Jesús Duque-Afonso,

First published: 03 February 2025

Graphical Abstract
LETTER
Open Access

oa

Limited stage mantle cell lymphoma: A real-world study of primary treatment and prognosis in Sweden 2006–2018
Alexandra Albertsson-Lindblad, Sara Ekberg, Ingrid Glimelius, Fredrik Ellin, Kristina Sonnevi, Catharina Lewerin, Lena Brandefors, Karin E. Smedby, Mats Jerkeman,

First published: 27 January 2025
ARTICLE
Open Access

oa

Combining SKY92 gene expression profiling and FISH (according to R2-ISS) defines ultra-high-risk Multiple Myeloma
Xiang Zhou, Annika Hofmann, Benedict Engel, Cornelia Vogt, Silvia Nerreter, Yoko Tamamushi, Friederike Schmitt, Maria leberzammer, Emilia Stanojkovska, Marietta Truger, Xianghui Xiao, Christine Riedhammer, Maximilian J. Steinhardt, Mara John, Julia Mersi, Seungbin Han, Umair Munawar, Johannes M. Waldschmidt, Claudia Haferlach, Hermann Einsele, Leo Rasche, K. Martin Kortüm,

First published: 23 January 2025

Graphical Abstract
LETTER
Open Access

oa

Prevalence of type I Gaucher disease in patients with smoldering or multiple myeloma: Results from the prospective, observational CHAGAL study
Sonia Morè, Irene Federici, Alessandra Bossi, Serena Rupoli, Erika Morsia, Valentina M. Manieri, Attilio Olivieri, Maria T. Petrucci, Francesca Fazio, Chiara Lisi, Silvia Sorella, Adele D. Paoli, Francesca Farina, Anna Mele, Rossella De Francesco, Antonino Greco, Francesca Fioritoni, Carmine Liberatore, Tommaso Caravita di Toritto, Attilio Tordi, Angela Rago, Agostina Siniscalchi, Marino Brunori, Nicola Sgherza, Pellegrino Musto, Angela Amendola, Angelo Vacca, Antonio G. Solimando, Assunta Melaccio, Antonio Palma, Lorella M. A. Melillo, Lucia Ciuffreda, Silvia Gentili, Gabriele Buda, Maria L. Del Giudice, Antonietta P. Falcone, Patrizia Tosi, Simona Tomassetti, Francesco Rotondo, Alessandro Gozzetti, Piero Galieni, Miriana Ruggieri, Ferdinando Frigeri, Rosario Bianco, Alessandra Lombardo, Fabio Trastulli, Laura Corvatta, Carmela Zizzo, Giovanni Duro, Massimo Offidani,

First published: 22 January 2025
ARTICLE
Open Access

oa

Detection of clinically relevant variants in the TP53 gene below 10% allelic frequency: A multicenter study by ERIC, the European Research Initiative on CLL
Sarka Pavlova, Jitka Malcikova, Lenka Radova, Silvia Bonfiglio, Jack B. Cowland, Christian Brieghel, Mette K. Andersen, Maria Karypidou, Bella Biderman, Michael Doubek, Gregory Lazarian, Inmaculada Rapado, Matthijs Vynck, Naomi A. Porret, Martin Andres, Dina Rosenberg, Dvora Sahar, Carolina Martínez-Laperche, Ismael Buño, Andrew Hindley, David Donaldson, Julio B. Sánchez, José A. García-Marco, Alicia Serrano-Alcalá, Blanca Ferrer-Lores, Concepción Fernández-Rodriguez, Beatriz Bellosillo, Stephan Stilgenbauer, Eugen Tausch, Hero Nikdin, Fiona Quinn, Emer Atkinson, Lisette van de Corput, Cafer Yildiz, Cristina Bilbao-Sieyro, Yanira Florido, Christian Thiede, Caroline Schuster, Anastazja Stoj, Sylwia Czekalska, Anastasia Chatzidimitriou, Stamatia Laidou, Audrey Bidet, Charles Dussiau, Friedel Nollet, Giovanna Piras, Maria Monne, Svetlana Smirnova, Eugene Nikitin, Ivan Sloma, Alexis Claudel, Laetitia Largeaud, Loïc Ysebaert, Peter J. M. Valk, Amy Christian, Renata Walewska, David Oscier, Marta Sebastião, Maria Gomes da Silva, Piero Galieni, Mario Angelini, Davide Rossi, Valeria Spina, Sónia Matos, Vânia Martins, Tomasz Stokłosa, Monika Pepek, Panagiotis Baliakas, Rafa Andreu, Irene Luna, Tiina Kahre, Ülle Murumets, Tereza Pikousova, Terezia Kurucova, Sophie Laird, Daniel Ward, Miguel Alcoceba, Ana Balanzategui, Lydia Scarfo, Francesca Gandini, Ettore Zapparoli, Adoración Blanco, Pau Abrisqueta, Ana E. Rodríguez-Vicente, Rocío Benito, Clotilde Bravetti, Frédéric Davi, Paula Gameiro, Joaquin Martinez-Lopez, Bárbara Tazón-Vega, Fanny Baran-Marszak, Zadie Davis, Mark Catherwood, Andrey Sudarikov, Richard Rosenquist, Carsten U. Niemann, Kostas Stamatopoulos, Paolo Ghia, Sarka Pospisilova,

First published: 20 January 2025
ARTICLE
Open Access

oa

Secondary lesions and sensitivity to signaling inhibitors in iAMP21 acute lymphoblastic leukemia
Femke M. Hormann, Anna Østergaard, Stijn van den Broek, Aurélie Boeree, Cesca van de Ven, Gabriele Escherich, Edwin Sonneveld, Judith M. Boer, Monique L. den Boer,

First published: 20 January 2025

Collections: Pediatric Hematology

Graphical Abstract
LETTER
Open Access

oa

Efficacy of anti-PD1 therapy in extranodal NK/T cell lymphoma: A matched cohort analysis from the LYSA
Amira Marouf, Sammara Chaubard, Raphaël Liévin, Jean-Marie Michot, Nicolas Molinari, Julien Rossignol, Doriane Cavalieri, Camille Golfier, Olivier Allangba, Laure Philippe, Benoît Tessoulin, Adrien Chauchet, Bénédicte Deau, Lucie Oberic, Jacques Vargaftig, Aline Moignet, Aline Clavert, Rémy Dulery, Gabriel Brisou, Stéphanie Tardy, Virginie Fataccioli, Roch Houot, René O. Casasnovas, Catherine Thieblemont, Hervé Ghesquières, Sylvain Carras, Steven Le Gouill, Guillaume Cartron, Vincent Ribrag, Morgane Cheminant, Ambroise Marçais, Felipe Suarez, Aurélien Marabelle, Olivier Tournilhac, Gandhi Damaj, Philippe Gaulard, Laurence De Leval, François Lemonnier, Emmanuel Bachy, Sylvie Chevret, Olivier Hermine, Lucile Couronné, Arnaud Jaccard,

First published: 20 January 2025
ARTICLE
Open Access

oa

The CD123 antibody–drug conjugate pivekimab sunirine exerts profound activity in preclinical models of pediatric acute lymphoblastic leukemia
Ben Watts, Christopher M. Smith, Kathryn Evans, Andrew J. Gifford, Sara M. A. Mohamed, Stephen W. Erickson, Eric J. Earley, Steven Neuhauser, Timothy M. Stearns, Vivek M. Philip, Jeffrey H. Chuang, Patrick A. Zweidler-McKay, Sribalaji Lakshmikanthan, Emily L. Jocoy, Carol J. Bult, Beverly A. Teicher, Malcolm A. Smith, Richard B. Lock,

First published: 17 January 2025

Collections: Pediatric Hematology
ARTICLE
Open Access

oa

Extracellular vesicles from chronic lymphocytic leukemia cells promote leukemia aggressiveness by inducing the differentiation of monocytes into nurse-like cells via an RNA-dependent mechanism
Nathan Dubois, David Van Morckhoven, Laurentijn Tilleman, Filip Van Nieuwerburgh, Dominique Bron, Laurence Lagneaux, Basile Stamatopoulos,

First published: 16 January 2025

Graphical Abstract
LETTER
Open Access

oa

Long-term results of a phase 1/1b study of ibrutinib plus umbralisib for relapsed/refractory chronic lymphocytic leukemia
Christine E. Ryan, Yue Ren, Svitlana Tyekucheva, Jon E. Arnason, Adam M. Boruchov, Caron A. Jacobson, David C. Fisher, Hari Miskin, Peter Sportelli, Jennifer R. Brown, Matthew S. Davids,

First published: 15 January 2025
LETTER
Open Access

oa

Postoperative stage 0 Hodgkin lymphoma. Is surgery alone a curative option?
Audrey Couturier, Alexandra Judet, Mohamed Touati, Thomas Nivet, Pierre Daufresne, Fabien Claves, Eric Durot, Rémy Duléry, Roch Houot, Guillaume Manson,

First published: 15 January 2025
ARTICLE
Open Access

oa

Prognostic significance of immune reconstitution following CD19 CAR T-cell therapy for relapsed/refractory B-cell lymphoma
Sophia Stock, Veit L. Bücklein, Viktoria Blumenberg, Giulia Magno, Alica-Joana Emhardt, Alessandra M. E. Holzem, David M. Cordas dos Santos, Christian Schmidt, Stefanie Grießhammer, Lisa Frölich, Sebastian Kobold, Michael von Bergwelt-Baildon, Kai Rejeski, Marion Subklewe,

First published: 13 January 2025

Graphical Abstract

$Prognostic significance of immune reconstitution following CD19 CAR T-cell therapy for relapsed/refractory B-cell lymphoma$
ARTICLE
Open Access

oa

Proliferating CLL cells express high levels of CXCR4 and CD5
Daniel Friedman, Drshika P. Mehtani, Jennifer B. Vidler, Piers E. M. Patten, Robbert Hoogeboom,

First published: 17 December 2024

Graphical Abstract
ARTICLE
Open Access

oa

Expression profile of Bcl-2 family proteins in newly diagnosed multiple myeloma patients
Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz-Krzeminska, Ignacio J. Cardona-Benavides, Myriam Cuadrado, Isabel Isidro, María-José Calasanz, Manuela Fernandez, Ramón García-Sanz, Noemi Puig, M. Teresa Cedena, Bruno Paiva, Laura Rosiñol, Joaquín Martínez-López, Joan Bladé, Juan J. Lahuerta, Jesús F. San Miguel, María V. Mateos, Luis A. Corchete, Norma C. Gutiérrez, GEM/PETHEMA cooperative study group,

First published: 13 December 2024

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oa Loss of CYLD promotes splenic marginal zone lymphoma

Graphical Abstract

oa Age- and gender-specific molecular characteristics of diffuse large B-cell lymphoma: Results from clinical trials of the DSHNHL/GLA

Graphical Abstract

oa Salvage treatment after covalent BTKi failure: An unmet need in clinical practice in Waldenstrom macroglobulinemia

oa Outcomes of patients with relapsed or refractory primary mediastinal B-cell lymphoma treated with anti-CD19 CAR-T cells: CARTHYM, a study from the French national DESCAR-T registry

Graphical Abstract

oa Single-cell DNA and surface protein characterization of high hyperdiploid acute lymphoblastic leukemia at diagnosis and during treatment

Graphical Abstract

oa Chimeric antigen receptor T-cell therapy outcomes in T cell/histiocyte-rich large B-cell lymphoma and subsequent treatment strategies after disease progression: A GELTAMO/GETH study

oa Dynamic evolution of TCF3-PBX1 leukemias at the single-cell level under chemotherapy pressure

Graphical Abstract

oa Limited stage mantle cell lymphoma: A real-world study of primary treatment and prognosis in Sweden 2006–2018

oa Combining SKY92 gene expression profiling and FISH (according to R2-ISS) defines ultra-high-risk Multiple Myeloma

Graphical Abstract

oa Prevalence of type I Gaucher disease in patients with smoldering or multiple myeloma: Results from the prospective, observational CHAGAL study

oa Detection of clinically relevant variants in the TP53 gene below 10% allelic frequency: A multicenter study by ERIC, the European Research Initiative on CLL

oa Secondary lesions and sensitivity to signaling inhibitors in iAMP21 acute lymphoblastic leukemia

Graphical Abstract

oa Efficacy of anti-PD1 therapy in extranodal NK/T cell lymphoma: A matched cohort analysis from the LYSA

oa The CD123 antibody–drug conjugate pivekimab sunirine exerts profound activity in preclinical models of pediatric acute lymphoblastic leukemia

oa Extracellular vesicles from chronic lymphocytic leukemia cells promote leukemia aggressiveness by inducing the differentiation of monocytes into nurse-like cells via an RNA-dependent mechanism

Graphical Abstract

oa Long-term results of a phase 1/1b study of ibrutinib plus umbralisib for relapsed/refractory chronic lymphocytic leukemia

oa Postoperative stage 0 Hodgkin lymphoma. Is surgery alone a curative option?

oa Prognostic significance of immune reconstitution following CD19 CAR T-cell therapy for relapsed/refractory B-cell lymphoma

Graphical Abstract

oa Proliferating CLL cells express high levels of CXCR4 and CD5

Graphical Abstract

oa Expression profile of Bcl-2 family proteins in newly diagnosed multiple myeloma patients

Graphical Abstract

oa

Loss of CYLD promotes splenic marginal zone lymphoma

oa

Age- and gender-specific molecular characteristics of diffuse large B-cell lymphoma: Results from clinical trials of the DSHNHL/GLA

oa

Salvage treatment after covalent BTKi failure: An unmet need in clinical practice in Waldenstrom macroglobulinemia

oa

Outcomes of patients with relapsed or refractory primary mediastinal B-cell lymphoma treated with anti-CD19 CAR-T cells: CARTHYM, a study from the French national DESCAR-T registry

oa

Single-cell DNA and surface protein characterization of high hyperdiploid acute lymphoblastic leukemia at diagnosis and during treatment

oa

Chimeric antigen receptor T-cell therapy outcomes in T cell/histiocyte-rich large B-cell lymphoma and subsequent treatment strategies after disease progression: A GELTAMO/GETH study

oa

Dynamic evolution of TCF3-PBX1 leukemias at the single-cell level under chemotherapy pressure

oa

Limited stage mantle cell lymphoma: A real-world study of primary treatment and prognosis in Sweden 2006–2018

oa

Combining SKY92 gene expression profiling and FISH (according to R2-ISS) defines ultra-high-risk Multiple Myeloma

oa

Prevalence of type I Gaucher disease in patients with smoldering or multiple myeloma: Results from the prospective, observational CHAGAL study

oa

Detection of clinically relevant variants in the TP53 gene below 10% allelic frequency: A multicenter study by ERIC, the European Research Initiative on CLL

oa

Secondary lesions and sensitivity to signaling inhibitors in iAMP21 acute lymphoblastic leukemia

oa

Efficacy of anti-PD1 therapy in extranodal NK/T cell lymphoma: A matched cohort analysis from the LYSA

oa

The CD123 antibody–drug conjugate pivekimab sunirine exerts profound activity in preclinical models of pediatric acute lymphoblastic leukemia

oa

Extracellular vesicles from chronic lymphocytic leukemia cells promote leukemia aggressiveness by inducing the differentiation of monocytes into nurse-like cells via an RNA-dependent mechanism

oa

Long-term results of a phase 1/1b study of ibrutinib plus umbralisib for relapsed/refractory chronic lymphocytic leukemia

oa

Postoperative stage 0 Hodgkin lymphoma. Is surgery alone a curative option?

oa

Prognostic significance of immune reconstitution following CD19 CAR T-cell therapy for relapsed/refractory B-cell lymphoma

oa

Proliferating CLL cells express high levels of CXCR4 and CD5

oa

Expression profile of Bcl-2 family proteins in newly diagnosed multiple myeloma patients